CELLEGY PHARMACEUTICALS INC
DEF 14A, 2000-04-12
PHARMACEUTICAL PREPARATIONS
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                                  SCHEDULE 14A
                                 (Rule 14a-101)

                     INFORMATION REQUIRED IN PROXY STATEMENT
                            SCHEDULE 14A INFORMATION

           PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES
                     EXCHANGE ACT OF 1934 (AMENDMENT NO. __)

Filed by the Registrant                       [X]
Filed by a party other than the Registrant    [ ]

Check the appropriate box:
[ ]  Preliminary Proxy Statement           [ ]  Confidential, for Use of the
[X]  Definitive Proxy Statement                 Commission Only (as permitted by
[ ]  Definitive Additional Materials            Rule 14a-6(e)(2))
[ ]  Soliciting Material Pursuant to
     Rule 14a-11(c) or Rule 14a-12

                          Cellegy Pharmaceuticals, Inc.
           ----------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)

           ----------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of filing fee (Check the appropriate box):

[X]     No fee required.
[ ]     Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

(1)     Title of each class of securities to which transactions applies:

(2)     Aggregate number of securities to which transactions applies:

(3)     Per unit  price  or  other  underlying  value  of  transaction  computed
        pursuant  to  Exchange  Act Rule 0-11 (set forth the amount on which the
        filing fee is calculated and state how it was determined):

(4)     Proposed maximum aggregate value of transaction:

(5)     Total fee paid:

        [ ]      Fee paid previously with preliminary materials.

        [ ]      Check  box if any  part of the fee is  offset  as  provided  by
                 Exchange Act Rule  0-11(a)(2) and identify the filing for which
                 the offsetting fee was paid  previously.  Identify the previous
                 filing  by  registration  statement  number,  or  the  Form  or
                 Schedule and the date of its filing.

(1)     Amount previously paid:

(2)     Form, Schedule or Registration Statement No.:

(3)     Filing party:

(4)     Date filed:

<PAGE>

                          CELLEGY PHARMACEUTICALS, INC.

                      349 Oyster Point Boulevard, Suite 200
                      South San Francisco, California 94080

                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                           To Be Held on May 31, 2000

To the Shareholders:

     The  Annual  Meeting  of  Shareholders  of  Cellegy  Pharmaceuticals,  Inc.
("Cellegy")  will  be  held  at 349 Oyster Point Boulevard, Suite 200, South San
Francisco,  California  on May 31, 2000, at 8:30 a.m., P.D.T., for the following
purposes:

       1. To  elect  seven  members of the Board of Directors to serve until the
          next annual meeting of shareholders;

       2. To approve an amendment to Cellegy's  1995 Equity  Incentive Plan (the
          "Plan") to increase by 1,000,000 shares,  to 3,450,000,  the number of
          shares of Cellegy common stock available for issuance  pursuant to the
          Plan;

       3. To approve an amendment to Cellegy's 1995 Directors' Stock Option Plan
          (the "Directors' Plan") to increase by 100,000 shares, to 250,000, the
          number  of shares of  Cellegy  common  stock  available  for  issuance
          pursuant to the Directors' Plan.

       4. To   ratify  the  appointment  of  Ernst  &  Young  LLP  as  Cellegy's
          independent auditors for the 2000 fiscal year; and

       5. To  transact  such  other  business  as  may  properly come before the
          meeting or any adjournments thereof.

     The  foregoing  items of  business  are more fully  described  in the Proxy
Statement accompanying this notice.

     Only  shareholders of record at the close of business on April 10, 2000 are
entitled  to notice of, and to vote at, the  meeting  and any  adjournments  and
postponements thereof.

     You are cordially invited to attend the meeting in person.

                                     By Order of the Board of Directors


                                     /S/ K. Michael Forrest

                                     K. Michael Forrest
                                     President and Chief Executive Officer

South San Francisco, California
April 14, 2000


- --------------------------------------------------------------------------------
  WHETHER  OR NOT YOU PLAN TO ATTEND  THE  MEETING,  PLEASE  SIGN AND RETURN THE
  ACCOMPANYING  PROXY CARD AS SOON AS POSSIBLE IN THE ENCLOSED  POSTAGE  PREPAID
  ENVELOPE. THANK YOU FOR ACTING PROMPTLY.
- --------------------------------------------------------------------------------

<PAGE>

                          CELLEGY PHARMACEUTICALS, INC.

                      349 Oyster Point Boulevard, Suite 200
                      South San Francisco, California 94080

                                 (650) 616-2200

                              ---------------------

                         Annual Meeting of Shareholders
                                 PROXY STATEMENT

                              ---------------------

                                 April 14, 2000

To the Shareholders:

     The enclosed  proxy is  solicited on behalf of the Board of Directors  (the
"Board") of Cellegy Pharmaceuticals, Inc., a California corporation ("Cellegy"),
for use at Cellegy's  annual meeting of shareholders  and any  adjournments  and
postponements (the "Annual Meeting") to be held at 8:30 a.m., P.D.T., on May 31,
2000, at 349 Oyster Point Boulevard, Suite 200, South San Francisco, California.
Only  shareholders  of record on the close of  business  on April 10,  2000 (the
"Record Date") are entitled to notice of, and to vote at, the Annual Meeting. On
the  Record  Date,  12,078,118  shares of common  stock,  no par value  ("common
stock"),  were  outstanding  and  entitled  to vote.  A  majority  of the shares
outstanding on the Record Date will  constitute a quorum for the  transaction of
business.  This Proxy  Statement,  our Annual  Report to  Shareholders,  and the
accompanying  form of proxy were first mailed to  shareholders on or about April
14, 2000.

                   VOTING RIGHTS AND SOLICITATION OF PROXIES

     Holders of common  stock are  entitled to one vote for each share of common
stock  held,  except that in the  election of  directors  each  shareholder  has
cumulative  voting rights as described below. The authorized number of directors
currently is seven. For the election of directors,  any shareholder may exercise
cumulative voting rights, which enable the shareholder to cast a number of votes
equal to the number of shares held  multiplied  by the number of directors to be
elected  by the  class of stock  held.  All such  votes may be cast for a single
nominee or may be distributed  among any or all of the nominees.  Proxies cannot
be voted for a greater number of persons than the number of nominees  named.  In
order to be entitled to cumulate  votes,  a shareholder  must give notice at the
Annual Meeting,  prior to voting,  of the  shareholder's  intention to do so. In
addition,  no  shareholder  will be entitled  to cumulate  votes for a candidate
unless that candidate's name has been placed in nomination before the voting. If
one shareholder gives such a notice,  all shareholders may cumulate their votes.
In such an event,  the proxy holder may allocate  among the Board of  Directors'
nominees the votes  required by proxies in the proxy  holder's sole  discretion.
Shareholders  are  requested,  by  means  of the  accompanying  proxy,  to grant
discretionary authority to the proxy holders to cumulate votes.

     In the  event  that a  broker  indicates  on a proxy  that it does not have
discretionary  authority as to certain  shares to vote on a  particular  matter,
those shares will be counted for purposes of determining the presence or absence
of a quorum for the  transaction of business but will not be considered  present
and voting with respect to that matter.

     Directors  will be  elected  by a  plurality  of the votes of the shares of
common stock present in person or represented by proxy at the Annual Meeting and
entitled to vote on the election of directors. Proposals Nos. 2, 3 and 4 require
for  approval  the  affirmative  vote of the  majority of shares of common stock
present in person or  represented by proxy at the Annual Meeting and entitled to
vote on such proposals. For purposes of such Proposals, (i) the aggregate number
of  votes  entitled  to be  cast  by  all  shareholders  present  in  person  or
represented  by proxy at the Annual  Meeting,  whether those  shareholders  vote
"for,"  "against,"  "abstain"  or give no  instructions,  will  be  counted  for
purposes of determining the minimum

                                        1

<PAGE>

number of  affirmative  votes  required to approve the proposal,  (ii) the total
number of shares cast "for"  Proposal  Nos.  2, 3 and 4 or  returning a properly
signed  proxy  but  giving no  instructions  will be  counted  for  purposes  of
determining   whether  sufficient   affirmative  votes  have  been  cast,  (iii)
abstentions  will be treated as shares that are present and  entitled to vote on
the proposal and will have the same effect as a vote against the  proposal,  and
(iv) broker  non-votes  will not be counted as present or voting with respect to
such proposals.

     In the  event  that  sufficient  votes in favor  of the  proposals  are not
received by the date of the Annual  Meeting,  the  persons  named as proxies may
propose  one or more  adjournments  of the  Annual  Meeting  to  permit  further
solicitations  of proxies.  Any such  adjournment  would require the affirmative
vote of the majority of the outstanding  shares present in person or represented
by proxy at the Annual Meeting.

     We will bear the cost of  preparing,  assembling,  printing and mailing the
Proxy  Statement,  the Notice of Annual Meeting of Shareholders and the enclosed
form of proxy, as well as the cost of soliciting  proxies relating to the Annual
Meeting.  Following  the  original  mailing of the proxies and other  soliciting
materials, Cellegy will request that the brokers, custodians, nominees and other
record  holders  forward copies of the proxy and other  soliciting  materials to
persons for whom they hold shares of common stock and request  authority for the
exercise of  proxies.  In such  cases,  upon the request of the record  holders,
Cellegy will reimburse such holders for their reasonable expenses.  The original
solicitation of proxies by mail may be  supplemented by telephone,  telegram and
personal solicitation by directors, officers and employees of Cellegy.

                             REVOCABILITY OF PROXIES

     Any  shareholder  giving  a  proxy  in the  form  accompanying  this  Proxy
Statement  has the power to  revoke  the proxy  before  its use.  A proxy can be
revoked (i) by an instrument of revocation  delivered  before the Annual Meeting
to the Secretary of Cellegy at the principal  executive offices,  (ii) by a duly
executed  proxy  bearing a later date or time than the date or time of the proxy
being revoked, or (iii) by voting in person at the Annual Meeting.  Please note,
however,  that if a shareholder's shares are held of record by a broker, bank or
other nominee and that  shareholder  wishes to vote at the Annual  Meeting,  the
shareholder  must bring to the Annual Meeting a letter from the broker,  bank or
other nominee confirming that shareholder's  beneficial ownership of the shares.
Attendance at the Annual Meeting will not by itself revoke a proxy.

                                        2

<PAGE>

                                PROPOSAL NO. 1

                              ELECTION OF DIRECTORS

Nominees

     Seven  directors  are to be elected  to the Board at the Annual  Meeting to
serve until the next Annual  Meeting and until their  respective  successors are
elected  and  qualified  or until the  death,  resignation,  or  removal  of the
director.  Each of the  nominees is  currently  a director  of  Cellegy.  If any
nominee is unable or unwilling to serve as a director,  the proxies may be voted
for such substitute nominee as the proxy holder may determine.  The Board has no
reason  to  believe  that any of the  persons  named  below  will be  unable  or
unwilling  to serve as a director if  elected.  Proxies  received  will be voted
"FOR" the  election of the  nominees  named below  unless the proxy is marked in
such a manner as to withhold authority so to vote.

     The names of the nominees and certain  information about them are set forth
below:

<TABLE>
<CAPTION>
                                                              Principal                   Director
                Name                     Age                  Occupation                   Since
- --------------------------------------   -----   --------------------------------------   ----------
<S>                                       <C>    <C>                                        <C>
K. Michael Forrest  ..................    56     President, Chief Executive Officer,        1996
                                                   and Director of Cellegy

Carl R. Thornfeldt, M.D.  ............    48     Medical Director and Chairman of           1989
                                                   the Board of Cellegy

Jack L. Bowman(2)   ..................    67     Former Group Chairman, Johnson &           1996
                                                   Johnson

Tobi B. Klar, M.D.  ..................    45     Dermatologist and Associate Clinical       1995
                                                   Professor in Dermatology, Albert
                                                   Einstein Medical Center

Ronald J. Saldarini, Ph.D.(3)   ......    60     Former President, Wyeth Lederle            1999
                                                   Vaccines

Alan A. Steigrod(2)    ...............    62     Managing Director, Newport                 1996
                                                   HealthCare Ventures

Larry J. Wells(3)   ..................    57     President, Wells Investment Group          1989
<FN>
- ------------

(2) Member of the Compensation Committee.

(3) Member of the Audit Committee.
</FN>
</TABLE>

     Directors  hold office until the next Annual  Meeting of  shareholders  and
until their  respective  successors  have been elected and qualified.  Executive
officers are chosen by and serve at the  discretion  of the Board of  Directors,
subject to any written employment agreements with Cellegy.

     K.  Michael  Forrest. Mr.  Forrest became President, CEO, and a director in
December  1996. From January 1996 to November 1996, he served as a biotechnology
consultant  for  Cellegy.  From  November  1994  to  December 1995, he served as
President  and  CEO  of  Mercator Genetics, a public biotechnology company. From
March  1991  to  June  1994,  he  served  as  President and CEO of Transkaryotic
Therapies,  Inc., a public biotechnology company. From 1968 to 1991, Mr. Forrest
held  a  series  of  positions with Pfizer, Inc. and senior management positions
with  American  Cyanamid,  including  Vice President of Lederle U.S. and Lederle
International.  He  is  currently  a  director  of  AlphaGene  Inc.,  a  private
functional   genomics  company,  and  INEX  Pharmaceuticals,  a  public  company
developing anti-cancer products.

     Carl  R.  Thornfeldt,  M.D. Dr.  Thornfeldt  is a co-founder of Cellegy, as
well  as  a  physician,  board  certified  in dermatology. He has been Cellegy's
Medical  Director  since  our inception and has been Chairman of the Board since
1994.  Dr. Thornfeldt also served as acting CEO from July 1996 to December 1996.
Since  1983, Dr. Thornfeldt has maintained a private dermatology practice and is
an  Assistant  Clinical  Professor  in  Dermatology  at the University of Oregon
Health  Sciences  Center.  He  currently  is  also  a consultant to Cellegy. Dr.
Thornfeldt  received  his  M.D.  from  the  University of Oregon Health Sciences
Center.  He completed his dermatology residency at the University of California,
San Diego.

                                        3

<PAGE>

     Jack  L.  Bowman. Mr.  Bowman  became  a  director  in December 1996. He is
currently  a  consultant  to  various  pharmaceutical and biotechnology industry
groups.  From  August  1987  to  January  1994, he was Company Group Chairman at
Johnson  &  Johnson,  where  he  managed  much  of  its  global  diagnostic  and
pharmaceutical  businesses.  Before  then,  Mr.  Bowman held executive positions
with   CIBA-Geigy  and  American  Cyanamid,  where  he  had  responsibility  for
worldwide  pharmaceutical, medical device, and consumer product divisions. He is
currently  a  director  of  NeoRx  Corp.,  CytRx Corp., Cell Therapeutics, Inc.,
Targeted Genetics, Inc. and Osiris Therapeutics.

     Tobi  B. Klar, M.D. Dr. Klar became a director of Cellegy in June 1995. She
is  a  physician,  board  certified  in  dermatology.  Since  1986, Dr. Klar has
maintained  a  private  dermatology practice and has served as Co-Chairperson of
the  Department  of  Dermatology  at  New  Rochelle Hospital Medical Center, New
Rochelle,  New  York,  and Associate Clinical Professor in dermatology at Albert
Einstein  Medical  Center in New York City. Dr. Klar holds a M.D. from the State
University of New York.

     Ronald J. Saldarini,  Ph.D. Dr.  Saldarini  became a director in July 1999,
after  retiring from American Home  Products.  From 1994 until July 1999, he was
President of Wyeth Lederle Vaccines. He was also President of the Lederle-Praxis
Biologics Division from 1989 to 1994, and Vice President,  Lederle Laboratories,
both part of American  Cyanamid  Company,  prior to its  acquisition by American
Home Products in 1994. Dr.  Saldarini has been a member of the National  Vaccine
Advisory Committee,  the National Advisory Commission on Childhood Vaccines, and
was a National Institutes of Health postdoctoral fellow at UCLA's Brain Research
Institute.  He  received  his Ph.D.  in  Physiology  and  Biochemistry  from the
University  of  Kansas,  and a  B.A.  in  Biochemistry  and  Zoology  from  Drew
University.

     Alan  A.  Steigrod. Mr.  Steigrod  became  a  director  in July 1996. Since
January  1996  he  has  been  Managing  Director of Newport HealthCare Ventures,
which  invests  in  and  advises biopharmaceutical companies. From March 1993 to
November  1995,  he  served as President and CEO of Cortex Pharmaceuticals, Inc.
From  February  1991  to February 1993, he worked as a biotechnology consultant.
From  March  1981 through February 1991, Mr. Steigrod held a series of executive
positions  with Glaxo, Inc., serving as Chairman of Glaxo's operating committee,
as  well  as  on  its  Board  of  Directors. Prior to Glaxo, Mr. Steigrod held a
number  of  senior  management positions with Boehringer Ingelheim, Ltd. and Eli
Lilly & Co. He is currently a director of Sepracor Inc. and NeoRx Corporation.

     Larry  J.  Wells. Mr.  Wells  became a director of Cellegy in 1989. For the
past  seventeen  years, he has been a venture capitalist. He is the President of
Wells  Investment  Group,  the  General  Partner  of  Daystar  Partners, and the
founder  of  Sundance  Venture Partners, L.P., a venture capital fund. Mr. Wells
is a director of Identix, Isonics Corp., Wings America and Legacy Brands.

Board of Directors Meetings and Committees

     During the fiscal year ended December 31, 1999 ("fiscal  1999"),  the Board
held eight meetings,  including telephone conference meetings.  Each nominee who
was a director  during  fiscal 1999 attended at least 75% of the number of Board
meetings,  and the total number of meetings held by all committees on which such
director  served that were held during fiscal 1999,  during the time such person
was a director.

     Standing  committees  of  the  Board  include  an  Audit  Committee  and  a
Compensation  Committee.  The Board does not have a  nominating  committee  or a
committee performing similar functions.

     Mr.  Wells  and  Dr.  Saldarini  are  the  current  members  of  the  Audit
Committee.  The  Audit  Committee  met one time during 1999. The Audit Committee
reviews  our  accounting  practices, internal control systems and meets with our
outside  auditors  concerning  the  scope  and terms of their engagement and the
results of their audits.

     Messrs.  Bowman and  Steigrod are the current  members of the  Compensation
Committee.  The  Compensation  Committee met three times during 1999,  including
telephonic  meetings,  and acted by  written  consent  twice.  The  Compensation
Committee  recommends  compensation  for officers and employees of Cellegy,  and
grants options and stock awards under our employee benefit plans.

                                        4

<PAGE>

Director Compensation

     Directors  employed  by  Cellegy  did not  receive  any  monetary  fees for
services performed for Cellegy during 1999. Outside directors are reimbursed for
their travel expenses related to Board meetings. In addition, they receive a fee
of $1,250 for each Board meeting  attended in person.  Also,  outside  directors
receive $500 for each committee meeting attended in person.

     Non-employee  directors of Cellegy are eligible to  participate in the 1995
Directors' Stock Option Plan (the "Directors'  Plan"). A total of 150,000 shares
of common stock are reserved for issuance to eligible  directors pursuant to the
Directors'   Plan.  The  Directors'  Plan  is  currently   administered  by  the
Compensation  Committee of the Board. On the date on which an eligible  director
is elected,  the director is granted a non-qualified stock option (normally with
a term of ten years) (an "Initial Option") to acquire 30,000 shares. Thereafter,
on the first business day after our annual meeting of shareholders,  an eligible
director will be granted a ten-year option (an "Annual Option") to acquire 8,000
shares.  The exercise  price of all such options is the fair market value of the
shares on the grant date. Initial Options generally are exercisable  immediately
with respect to 25% of the shares subject to the option,  and become exercisable
with  respect to the  remaining  shares  subject  to the option  upon the first,
second,  third and fourth anniversaries of the grant date. Annual Options become
exercisable with respect to 33.3% of the shares on each of the first, second and
third anniversary of the grant date. During fiscal 1999, Annual Options of 8,000
shares at an exercise  price of $5.00 per share were  granted to each of Jack L.
Bowman, Tobi B. Klar, M.D., Alan A. Steigrod and Larry J. Wells.

                 THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE
                  ELECTION OF EACH OF THE NOMINATED DIRECTORS.

                                 PROPOSAL NO. 2

             APPROVAL OF AMENDMENTS TO 1995 EQUITY INCENTIVE PLAN

General

     Shareholders  are being asked to approve an  amendment  to  Cellegy's  1995
Equity  Incentive  Plan (the  "Plan") to increase the number of shares of common
stock  reserved for issuance  thereunder  by 1,000,000  shares,  from  2,450,000
shares  to  3,450,000  shares.  The Board of  Directors  approved  the  proposed
amendment on February 29, 2000.  The Board  believes  that adding  shares to the
Plan is in the best  interests  of Cellegy as it will permit  Cellegy to attract
and retain key employees by providing them with  appropriate  equity  incentives
and thereby help to align their interests with those of Cellegy's  shareholders.
If a quorum is present, the affirmative vote of the holders of a majority of the
shares of common stock present or  represented at the Annual Meeting is required
for approval of the amendment to the Plan.

     The Plan was  approved by the Board and  Cellegy's  shareholders  effective
August 1995. The Board and the shareholders  approved  amendments to the Plan in
1997 and 1998 to increase the number of shares issuable under the Plan. The Plan
provides for awards of stock options, restricted stock, and stock bonuses. As of
March 31,  2000,  Cellegy  had thirty  employees,  all of whom were  eligible to
receive and currently  have awards under the Plan.  During 1999,  Cellegy issued
options  to acquire a total of 905,100  shares  under the Plan.  As of March 31,
2000,  209,737  shares were  available for future options and other awards under
the Plan.  On March 31,  2000,  the market  price of the common stock was $7.06.
Employees  and  officers  of Cellegy  have an  interest  in the  approval of the
proposed amendments to the Plan by virtue of their eligibility to receive awards
under the Plan.  Cellegy  will mail,  without  charge,  to each person to whom a
proxy  statement  is  delivered,  upon request of such person and by first class
mail within one business day of receipt of such request, a copy of the Plan. Any
such request should be directed as follows: Secretary,  Cellegy Pharmaceuticals,
Inc., 349 Oyster Point  Boulevard,  Suite 200,  South San Francisco,  California
94088; telephone number (650) 616-2200.

                THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE
                     APPROVAL OF THE AMENDMENT TO THE PLAN.

                                        5

<PAGE>

Summary of the Plan

     Administration.  The Plan is administered  by the Board,  and the Board has
delegated  administration to the Compensation  Committee (the  "Administrator").
The  Administrator  acts as the manager of the Plan,  and as such has the power,
subject  to the terms and  restrictions  set  forth in the Plan,  to select  the
persons  ("Participants")  to  receive  options  granted  pursuant  to the  Plan
("Options") or other awards under the Plan (collectively,  "Awards"), to fix the
number  of  shares  that  each  Participant  may  acquire,  to set the terms and
conditions of each Award (including any vesting or exercisability  provisions or
limitations  regarding  any Award  and/or  the shares of common  stock  relating
thereto,  and the  waiver,  amendment,  extension  or  acceleration  of any such
provisions  or  limitations),  to reduce the exercise  price of any Award to the
then  current  fair market  value if the fair market  value of the common  stock
covered by such Award shall have declined  since the date the Award was granted,
and to determine all other matters  relating to the Plan,  subject to applicable
law.  Determinations  made by the  Administrator  are final and  binding  on all
parties. The Administrator may delegate non-discretionary  administrative duties
to such  employees  of  Cellegy  as it  deems  proper.  The Plan at  present  is
administered by the Compensation Committee of the Board.

     Eligibility.  Every person who at the date on which an Award was granted to
the person (the "Grant  Date") is an  employee  of Cellegy or any  Affiliate  is
eligible to receive Awards,  including options that are intended to be incentive
stock options  ("ISOs") within the meaning of the Internal Revenue Code of 1986,
as amended (the  "Code").  Every person who at the Grant Date is a consultant to
Cellegy or any Affiliate,  or any person who is a director of Cellegy but not an
employee,  is  eligible  to  receive  Awards,  including  non-qualified  options
("NQOs"),  but is not eligible to receive  ISOs.  The term  "Affiliate"  means a
"parent corporation" or a "subsidiary  corporation" as defined in the applicable
provisions of the Code.

     Securities Subject to the Plan. As proposed to be amended, the total number
of shares that are reserved and available for issuance  pursuant to the exercise
of Awards  under the Plan is  3,450,000  shares.  If Proposal No. 2 amending the
Plan is approved,  then a total of 1,209,737 shares will be available for future
issuance  under the Plan.  The shares  covered by the  portion of any grant that
expires  unexercised under the Plan will become available again for grants under
the Plan.  The number of shares  reserved for issuance under the Plan is subject
to adjustment in accordance with the provisions for adjustment in the Plan.

     Granting  of  Options.  No Options  may be granted  under the Plan after 10
years  from the date the Board  initially  adopted  the Plan,  unless an earlier
expiration  date is specified by the  Administrator  at the Grant Date.  Options
generally expire 10 years from its Grant Date, except that an ISO granted to any
ten percent  shareholder  expires  five years from its Grant Date.  The exercise
price of an ISO or an NQO shall be determined in accordance  with the applicable
provisions of the Plan and the Code,  and for ISOs is at least equal to the fair
market value of the stock covered by the ISO at the Grant Date (110% of the fair
market value for ISOs granted to a ten percent shareholder).

     Each  Award  will be  evidenced  by a  written  agreement  (in the  case of
Options, referred to as the "Option Agreement," and in the case of other Awards,
referred  to as the  "Award  Agreement"),  in a form  satisfactory  to  Cellegy,
executed by Cellegy and the Participant to whom the Award is granted. Provisions
of Award  Agreements need not be the same for each  Participant.  Awards may, in
the sole discretion of the Administrator,  be exercisable  entirely at the Grant
Date or at such times and in such amounts as the Administrator may specify.

     Corporate Transactions. The Plan provides that if Cellegy is merged into or
consolidated with another  corporation under  circumstances where Cellegy is not
the  surviving  corporation,  is  liquidated  or  dissolved,  is  the  surviving
corporation  of a merger after which the  shareholders  of Cellegy  cease to own
their shares or other equity interests in Cellegy,  sells or otherwise  disposes
of substantially all its assets to another  corporation,  or completes any other
transaction which qualifies as a "corporate transaction" under Section 424(a) of
the Code  wherein  the  shareholders  of  Cellegy  give up all of  their  equity
interest in Cellegy,  the successor  corporation may assume,  convert or replace
any  outstanding  awards.  In the  alternative,  the successor  corporation  may
substitute  any  outstanding  awards  with  substantially  equivalent  awards or
provide  substantially  similar consideration to participants as was provided to
shareholders, after

                                        6

<PAGE>

taking into  consideration the existing  provisions of the Awards. The successor
corporation may also issue, in place of outstanding  shares of Cellegy held by a
Participant,   substantially   similar  shares  or  other  property  subject  to
repurchase  restrictions no less favorable to the Participant.  If the successor
corporation refuses to assume or substitute  outstanding  options,  such options
will expire on such transaction on such conditions as the Board determines.

     Payment of Exercise Price.  Except as described below,  payment in full, in
cash,  generally  must be made for all  stock  purchased  at the time a  written
notice of  exercise  is given to  Cellegy.  Proceeds  of any such  payment  will
constitute general funds of Cellegy. The exercise price of options granted under
the Plan may be paid as approved by the  Administrator at the time of grant: (a)
in cash (by  check);  (b) by  cancellation  of  indebtedness  of  Cellegy to the
Participant;  (c) by  surrender  of shares of Cellegy  common stock owned by the
Participant  for at least six months and having a fair market  value on the date
of surrender equal to the aggregate  exercise price of the option; (d) by tender
of a full recourse  promissory  note;  (e) by waiver of  compensation  due to or
accrued by the  Participant  for  services  rendered;  (f) by a "same-day  sale"
commitment  from  the  Participant  and a  National  Association  of  Securities
Dealers, Inc. ("NASD") broker; (g) by a "margin" commitment from the Participant
and a NASD broker; or (h) by any combination of the foregoing.

     Termination of Employment. Any Award or portion thereof that has not vested
on or before the date on which a  Participant  ceases,  for any reason,  with or
without cause,  to be an employee or director of, or a consultant to, Cellegy or
an Affiliate  ("Employment  Termination"),  expires upon the date of  Employment
Termination.  An Award or  portion  thereof  that has  vested  as of the date of
Employment  Termination,  to the extent  the Award has not then  expired or been
exercised,  is exercisable  for a period of 90 days after the date of Employment
Termination  or such shorter or longer time period not  exceeding  five years as
the Administrator may determine.  If, however,  Employment Termination is due to
the  disability  or  death  of the  Participant,  then  the  Participant  or the
Participant's  representative may, within 12 months after the date of Employment
Termination  or such shorter or longer time period not  exceeding  five years as
the Administrator  may determine,  exercise such Award rights to the extent they
were exercisable on the date of Employment Termination.

     Restricted  Stock and Bonus Stock.  Participants  awarded  Restricted Stock
must,  within  certain time periods  specified in the Plan,  pay to Cellegy,  if
required  by  applicable  law,  an  amount  equal to the par  value of the Stock
subject  to the  Award.  Subject  to the  provisions  of the Plan and the  Award
Agreement,  during a period set by the  Administrator,  commencing with, and not
exceeding 10 years from, the date of such award (the "Restriction  Period"), the
Participant may not sell, assign, transfer,  pledge or otherwise encumber shares
of  Restricted  Stock.  Within  these  limits,  the  Administrator  may  in  its
discretion  provide for the lapse of such  restrictions in installments  and may
accelerate or waive such  restrictions,  in whole or in part,  based on service,
performance  or  such  other  factors  or  criteria  as  the  Administrator  may
determine.  Except to the extent otherwise provided in the Award Agreement, upon
a Participant's Employment Termination during the Restriction Period, all shares
still subject to restriction will be forfeited by the Participant. The Plan also
allows the Administrator to make awards of Bonus Stock to a Participant.

     Amendment, Suspension or Termination of the Plan. The Board may at any time
amend,  alter,  suspend or discontinue  the Plan without  shareholder  approval,
except as required by  applicable  law;  provided,  however,  that no amendment,
alteration,  suspension or  discontinuation  shall be made that would impair the
rights of any  Participant  under  any Award  previously  granted,  without  the
Participant's  consent,  except to conform the Plan and Awards granted under the
Plan to the  requirements  of federal or other tax laws or the  requirements  of
Rule 16b-3.

     ERISA,  Internal  Revenue  Code.  The Plan is not  subject to the  Employee
Retirement  Income  Security Act of 1974  ("ERISA") and is not  qualified  under
Section 401(a) of the Code.

Summary of Federal Income Tax Consequences

     The  following  description  of  federal income tax consequences associated
with  participation  in  the Plan is based on current provisions of the Code and
administrative and judicial interpretations thereof. It

                                        7

<PAGE>

does not describe applicable state,  local, or foreign tax  considerations,  nor
does it discuss any estate or gift tax considerations.  The applicable rules are
complex and may vary depending upon a  participant's  individual  circumstances.
The following  description is thus necessarily  general and does not address all
of the potential  federal and other income tax consequences to every participant
of  the  Plan  or  in  connection  with   transactions   thereunder.   Moreover,
comprehensive  Treasury  regulations  covering  certain of the issues  described
below have been proposed but have not yet been adopted.

   Incentive Stock Options

     Option,  Exercise,  Alternative  Minimum Tax. A  Participant  will not have
taxable income upon the grant or exercise of an ISO. However, upon exercise, the
"Option  Spread"  (the amount by which the fair market value of the common stock
acquired  upon  exercise of the Option  (the  "Option  Shares") on the  relevant
measurement  date exceeds the exercise  price) is included on the  Participant's
"alternative minimum taxable income" in determining the Participant's  liability
for the "alternative  minimum tax." "Alternative  minimum tax" is imposed to the
extent it exceeds a Participant's regular tax liability. The maximum alternative
minimum  tax rate  applicable  to  individuals  is now 28%.  The  Option  Spread
generally  is  measured  for this  purpose on the day the  Option is  exercised;
however,  if both (i) the Option  Shares are subject to a  "substantial  risk of
forfeiture" (including a right of repurchase in favor of Cellegy and perhaps, in
the case of certain  officers,  limitations on the resale of such shares imposed
by Section 16(b) of the Exchange Act) and (ii) the Participant  does not make an
election  under  Section 83(b) of the Code with respect to such shares within 30
days after the  purchase  date (a  "Section  83(b)  Election"),  then the Option
Spread should be measured, and should be included in alternative minimum taxable
income,  on the  date  the  risk of  forfeiture  lapses.  (For  purposes  of the
alternative  minimum tax, the fair market value of Option Shares  acquired under
an ISO is determined by ignoring any restriction which by its terms may some day
lapse.)  Cellegy  receives no income tax deduction  upon grant or exercise of an
ISO but is entitled to a deduction  equal to the ordinary  income taxable to the
Participant upon a Disqualifying Disposition.

     In  general,  an ISO  must  be  exercised  within  90  days  of  Employment
Termination to retain the federal  income tax treatment  described  above.  This
90-day period does not apply in the case of a Participant  who dies while owning
an Option. In the case of a Participant who is permanently and totally disabled,
as defined in the Code,  this 90-day  period is extended to 12 months.  The Plan
allows Cellegy to extend the period during which a Participant  may exercise the
Option.  Any such  extension  may be treated as the grant of a new Option to the
Participant,  which must meet the requirements for ISO status on the date of the
agreement; in all events, if an Option is exercised more than three months after
Employment  Termination,  it will,  except  in the  cases of a  permanently  and
totally disabled or deceased Participant, not qualify as an ISO.

     Sale of Option Shares;  Disqualifying Dispositions. A Participant generally
will be entitled to long-term  capital gain  treatment  upon sale (other than to
Cellegy) or other  disposition  of Option Shares held longer than two years from
the grant date and one year from the date the  Participant  receives the shares.
If the  Option  Shares  are sold or  disposed  of  (including  by gift,  but not
including certain tax-free  exchanges) before both of these holding periods have
expired (a  "Disqualifying  Disposition"),  the Option Spread (but generally not
more than the  amount  of gain if the  Disqualifying  Disposition  is a sale) is
taxable as ordinary income.  For this purpose,  the Option Spread is measured at
the Exercise Date unless the Option Shares were subject to a substantial risk of
forfeiture  upon  purchase  and the  Participant  did not file a  Section  83(b)
Election,  in  which  event  the  Option  Spread  is  measured  at the  date the
restriction  lapsed. If gain on a Disqualifying  Disposition  exceeds the amount
treated as ordinary income,  the excess is capital gain, which will be long-term
if the Option  Shares were held for more than one year.  The holding  period for
Option  Shares  commences  with the Option  exercise  date unless the shares are
subject to a  substantial  risk of forfeiture  and no Section 83(b)  Election is
filed,  in which  event  the  holding  period  commences  with the date the risk
lapsed. A sale of common stock to Cellegy,  including use of common stock to pay
withholding  or withheld by Cellegy upon exercise of an ISO,  will  constitute a
redemption of such common stock and may be taxable as a dividend  unless certain
tests in the Code are met.

                                        8

<PAGE>

   Non-Qualified Stock Options

     Option;  Exercise; Tax Consequences to Cellegy. A Participant does not have
taxable income upon the grant of an NQO.  Federal income tax  consequences  upon
exercise will depend upon whether the Option Shares thereby acquired are subject
to a substantial  risk of forfeiture,  described above. If the Option Shares are
not subject to a substantial  risk of forfeiture (or if they are subject to such
a risk and the  Participant  files a Section 83(b)  Election with respect to the
shares),  the  Participant  will have  ordinary  income at the time of  exercise
measured by the Option Spread on the Exercise Date. The  Participant's tax basis
in the Option  Shares will be their fair market  value on the date of  exercise,
and the holding period for purposes of determining  whether capital gain or loss
upon sale is  long-term,  mid-term  or  short-term  also will begin with the day
after  transfer.  If the Option  Shares  are  restricted  and no  Section  83(b)
Election  is filed,  the  Participant  will not be taxable  upon  exercise,  but
instead will have  ordinary  income on the date the  restrictions  lapse,  in an
amount  equal to the  Option  Spread on the date of lapse.  In such a case,  the
Participant's holding period will also begin with the date of lapse.

     In either case, the amount of ordinary  income  recognized by a Participant
who is an employee  constitutes  "supplemental  wages" subject to withholding of
federal  income  and  employment  taxes  by  Cellegy,  and  Cellegy  receives  a
corresponding income tax deduction.

     Sale of Option  Shares.  Upon sale other  than to Cellegy of Option  Shares
acquired under an NQO, a Participant  generally  will recognize  capital gain or
loss  to  the  extent  of  the  difference   between  the  sale  price  and  the
Participant's tax basis in the shares,  which will be "mid-term" gain or loss if
the shares are held more than one year and  long-term if the shares are held for
more than 18 months.  A sale of shares to Cellegy will constitute  redemption of
such shares, which may be taxable as a dividend.

     Tax Compensation  Rights. Tax compensation  rights will constitute ordinary
wage income, subject to income and employment tax withholding,  when paid to the
Participant other than as proceeds of a loan.

                                 PROPOSAL NO. 3

          APPROVAL OF AMENDMENTS TO 1995 DIRECTORS' STOCK OPTION PLAN

General

     Shareholders  are being asked to approve an  amendment  to  Cellegy's  1995
Directors' Stock Option Plan (the  "Directors'  Plan") to increase the number of
shares of common stock reserved for issuance  thereunder  100,000  shares,  from
150,000 shares to 250,000 shares. The Board of Directors of Cellegy approved the
proposed  amendment on February 29, 2000.  The Board believes that adding shares
to the  Directors'  Plan is in the best  interest  of Cellegy as it will  permit
Cellegy to attract and retain key directors by providing  them with  appropriate
equity incentives.  If a quorum is present,  the affirmative vote of the holders
of a majority  of the shares of common  stock,  present  or  represented  at the
Annual Meeting is required for approval of the amendment to the Directors' Plan.

     The  Directors'  Plan was approved by the Board and Cellegy's  shareholders
effective August 1995. The Board and the shareholders approved amendments to the
Directors' Plan in 1997 and 1998 to increase the number if shares issuable under
the  Directors'  Plan and (in the case of the 1997  amendments)  to make certain
other amendments. The Directors' Plan provides for awards of non-qualified stock
options ("NQOs"). As of March 31, 2000, Cellegy had seven directors, of whom all
non-employee  directors were eligible to receive and have received  awards under
the Directors' Plan. During 1999, Cellegy issued a total of 32,000 stock options
under the Directors'  Plan.  Pursuant to the Directors' Plan, 6,000 options were
granted to non-executive directors as a group during 1997. As of March 31, 2000,
16,083  shares were  available  for future  options and other  awards  under the
Directors'  Plan.  On March 31,  2000,  the market price of the common stock was
$7.06. Non-employee directors of Cellegy have an interest in the approval of the
proposed  amendments to the  Directors'  Plan by virtue of their  eligibility to
receive awards under the Directors' Plan.  Cellegy will mail, without charge, to
each person to whom a proxy statement is delivered,  upon request of such person
and by first class mail within one business day

                                        9

<PAGE>

of  receipt  of  such  request,  a copy of the Directors' Plan. Any such request
should  be  directed  as  follows: Secretary, Cellegy Pharmaceuticals, Inc., 349
Oyster  Point  Boulevard,  Suite  200,  South  San  Francisco, California 94088;
telephone number (650) 616-2200.

                THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE
                APPROVAL OF THE AMENDMENT TO THE DIRECTORS' PLAN.

Summary of the Directors' Plan

     Administration.  The Directors' Plan is administered by the Board,  and the
Board  has  delegated   administration   to  the  Compensation   Committee  (the
"Administrator").  The Administrator acts as the manager of the Directors' Plan,
and as such has the power,  subject to the terms and  restrictions  set forth in
the Directors' Plan, to interpret the Directors' Plan and to determine all other
matters   relating  to  the  Directors'   Plan,   subject  to  applicable   law.
Determinations  made by the  Administrator are final and binding on all parties.
The Administrator may delegate  non-discretionary  administrative duties to such
employees  of  Cellegy as it deems  proper.  The  Directors'  Plan at present is
administered by the Compensation Committee of the Board.

     Eligibility.  Every person who at the date on which an Award was granted to
the  person  (the  "Grant  Date") who is a member of the Board of  Directors  of
Cellegy  (the  "Board"),  who is not also an  employee of Cellegy or any parent,
subsidiary or affiliate of Cellegy ("Outside  Directors") is eligible to receive
Awards  which shall be NQOs,  other than those  Board  members who are granted a
Board seat  pursuant to a financing  or  strategic  partnering  arrangement  (as
interpreted  by the  Compensation  Committee in its sole  discretion.)  The term
"Affiliate"  means a  "parent  corporation"  or a  "subsidiary  corporation"  as
defined in the applicable provisions of the Code.

     Securities  Subject to the Directors' Plan. As proposed to be amended,  the
total number of shares that are reserved and available for issuance  pursuant to
the exercise of Awards under the Directors' Plan is 250,000  shares.  A total of
16,083 shares are available for future  issuance under the Directors'  Plan. The
shares  covered by the portion of any grant that expires  unexercised  under the
Directors'  Plan will become  available  again for grants  under the  Directors'
Plan. The number of shares  reserved for issuance  under the Directors'  Plan is
subject to adjustment in accordance  with the  provisions  for adjustment in the
Directors' Plan.

     Granting of Options.  No Options may be granted under the  Directors'  Plan
after 10 years from the date the Board  initially  adopted the Directors'  Plan,
unless an  earlier  expiration  date is  specified  by the  Administrator.  Each
eligible  person  who  becomes a member of the Board is  granted  an option  for
30,000 shares of Cellegy  common stock on the first  business day after the date
such person is first  elected to the Board (the "Initial  Grant").  On the first
business  day after  Cellegy's  Annual  Meeting of  shareholders,  if an Outside
Director is still a member of the Board and has served  continuously as a member
of the Board for at least one year,  he or she is  granted  an option  for 8,000
shares of Cellegy common stock (the "Annual Grant"). Options generally expire 10
years from the Grant Date. The exercise price of the NQOs shall be determined in
accordance  with  the  applicable  provisions  of the  Code.  The  Annual  Grant
generally  vests  in  increments  of one  third  per  year  at the  end of  each
consecutive three-year period following the grant date.

     Each Award will be  evidenced  by a written  agreement  referred  to as the
"Award  Agreement," in a form  satisfactory to Cellegy,  executed by Cellegy and
the Participant to whom the Award is granted.

     Corporate Transactions. The Directors' Plan provides that in the event of a
dissolution  or  liquidation  of Cellegy,  a merger in which  Cellegy is not the
surviving  corporation,  a merger in which Cellegy is the surviving  corporation
but after which the  shareholders  of Cellegy cease to own their shares or other
equity interests in Cellegy,  the sale of all or substantially all of the assets
of Cellegy or any other transaction which qualifies as a "corporate transaction"
under  Section 424 of Internal  Revenue  Code of 1986,  as amended  (the "Code")
wherein the  shareholders  of Cellegy  give up all of their  equity  interest in
Cellegy,  the vesting of the options will  accelerate to become  exercisable  in
full.  Accelerated  options  which are not  exercised  prior to the close of the
corporate transaction shall terminate.

                                       10

<PAGE>

     Payment of Exercise Price.  Payment for the Shares  purchased upon exercise
of an Option may be made (a) in cash or by check;  (b) by surrender of shares of
common  stock of Cellegy  that have been owned by the Optionee for more than six
(6) months  (and which have been paid for within the meaning of  Securities  and
Exchange  Commission  ("SEC") Rule 144 and, if such shares were  purchased  from
Cellegy by use of a promissory  note, such note has been fully paid with respect
to such  shares) or were  obtained by the  Optionee  in the open public  market,
having a Fair Market  Value equal to the  exercise  price of the Option;  (c) by
waiver of compensation due or accrued to the Optionee for services rendered; (d)
provided  that a public  market for Cellegy  stock  exists,  through a "same day
sale"  commitment from the Optionee and a broker-dealer  that is a member of the
National  Association  of  Securities  Dealers  (an "NASD  Dealer")  whereby the
Optionee  irrevocably elects to exercise the Option and to sell a portion of the
Shares so purchased  to pay for the  exercise  price and whereby the NASD Dealer
irrevocably  commits upon  receipt of such Shares to forward the exercise  price
directly to Cellegy;  (e)  provided  that a public  market for  Cellegy's  stock
exists,  through a  "margin"  commitment  from the  Optionee  and a NASD  Dealer
whereby the Optionee irrevocably elects to exercise the Option and to pledge the
Shares so  purchased  to the NASD Dealer in a margin  account as security  for a
loan from the NASD Dealer in the amount of the exercise  price,  and whereby the
NASD  Dealer  irrevocably  commits  upon  receipt of such  Shares to forward the
exercise price directly to Cellegy; or (f) by any combination of the foregoing.

     Withholding  Taxes.  Prior to issuance  of the Shares  upon  exercise of an
Option,  the Optionee  shall pay or make  adequate  provision for any federal or
state withholding obligations of Cellegy, if applicable.

     Termination.  In general,  Options  expire ten (10) years after the date of
grant (the  "Expiration  Date").  The Option shall cease to vest if the Optionee
ceases to be a member of the Board.  The date on which the Optionee ceases to be
a member of the Board  shall be referred to as the  "Termination  Date".  If the
Optionee  ceases  to be a member of the Board  for any  reason  except  death or
disability,  then each  Option that has not  expired or been  exercised  and has
vested on the  Termination  Date, may be exercised by the Optionee  within three
(3) months after the Termination Date, but in no event later than the Expiration
Date.  If the  Optionee  ceases to be a member of the Board  because of death or
disability,  then each  Option that has not  expired or been  exercised  and has
vested  on the  Termination  Date,  may be  exercised  by the  Optionee  (or the
Optionee's legal representative) within twelve (12) months after the Termination
Date, but in no event later than the Expiration Date.

     Amendment or Termination of Directors' Plan. The Compensation Committee may
at any time  terminate or amend this  Directors'  Plan (but may not terminate or
amend the terms of any outstanding  option without the consent of the Optionee);
provided,  however,  that the  Compensation  Committee  shall not,  without  the
approval of the  shareholders  of Cellegy,  increase  the total number of Shares
available under this Directors' Plan or change the class of persons  eligible to
receive Options.  Further,  the provisions  regarding  eligibility and terms and
conditions  of option  grants  shall not be amended more than once every six (6)
months,  other than to comport with changes in the Code, the Employee Retirement
Income Security Act or the rules  thereunder.  In any case, no amendment of this
Directors'  Plan may  adversely  affect  any  then  outstanding  Options  or any
unexercised portions thereof without the written consent of the Optionee.

     ERISA,  Internal  Revenue Code. The  Directors'  Plan is not subject to the
Employee  Retirement  Income Security Act of 1974 ("ERISA") and is not qualified
under Section 401(a) of the Code.

Summary of Federal Income Tax Consequences

     The following  description  of federal income tax  consequences  associated
with  participation in the Directors' Plan is based on current provisions of the
Code  and  administrative  and  judicial  interpretations  thereof.  It does not
describe  applicable state,  local, or foreign tax  considerations,  nor does it
discuss any estate or gift tax considerations.  The applicable rules are complex
and may  vary  depending  upon a  participant's  individual  circumstances.  The
following  description is thus  necessarily  general and does not address all of
the potential  federal and other income tax consequences to every participant of
the Directors' Plan or in connection with transactions thereunder.

                                       11

<PAGE>

   Non-Qualified Stock Options

     Option;  Exercise; Tax Consequences to Cellegy. A Participant does not have
taxable income upon the grant of an NQO.  Federal income tax  consequences  upon
exercise will depend upon whether the Option Shares thereby acquired are subject
to a substantial  risk of forfeiture,  described above. If the Option Shares are
not subject to a substantial  risk of forfeiture (or if they are subject to such
a risk and the  Participant  files a Section 83(b)  Election with respect to the
shares),  the  Participant  will have  ordinary  income at the time of  exercise
measured by the Option Spread on the Exercise Date. The  Participant's tax basis
in the Option  Shares will be their fair market  value on the date of  exercise,
and the holding period for purposes of determining  whether capital gain or loss
upon sale is  long-term,  mid-term  or  short-term  also will begin with the day
after  transfer.  If the Option  Shares  are  restricted  and no  Section  83(b)
Election  is filed,  the  Participant  will not be taxable  upon  exercise,  but
instead will have  ordinary  income on the date the  restrictions  lapse,  in an
amount  equal to the  Option  Spread on the date of lapse.  In such a case,  the
Participant's holding period will also begin with the date of lapse.

     Sale of Option  Shares.  Upon sale other  than to Cellegy of Option  Shares
acquired under an NQO, a Participant  generally  will recognize  capital gain or
loss  to  the  extent  of  the  difference   between  the  sale  price  and  the
Participant's  tax basis in the shares,  which will be long-term gain or loss if
the  shares  are held  more than one year.  A sale of  shares  to  Cellegy  will
constitute a redemption of such shares, which may be taxable as a dividend.

     Tax Compensation  Rights. Tax compensation  rights will constitute ordinary
wage income, subject to income and employment tax withholding,  when paid to the
Participant other than as proceeds of a loan.

                                 PROPOSAL NO. 4

           RATIFICATION OF SELECTION OF INDEPENDENT PUBLIC ACCOUNTANTS

     Cellegy has engaged Ernst & Young LLP as its principal  independent  public
accountants  to perform the audit of Cellegy's  financial  statements for fiscal
2000. Ernst & Young LLP has audited Cellegy's  financial  statements since 1989.
The Board of Directors expects that representatives of Ernst & Young LLP will be
present at the Annual Meeting,  will be given an opportunity to make a statement
at the  meeting  if they  desire to do so, and will be  available  to respond to
appropriate questions.

                THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE
               RATIFICATION OF THE SELECTION OF ERNST & YOUNG LLP.

                                       12

<PAGE>

        SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

<TABLE>
     The following table sets forth, as of March 31, 2000,  certain  information
known to Cellegy  regarding  the ownership of shares of common stock by (i) each
person  known  to  Cellegy  to be a  beneficial  owner  of  more  that 5% of the
outstanding shares of common stock; (ii) each director; (iii) each Named Officer
(see "Executive Compensation"); and (iv) all directors and executive officers as
a group.

<CAPTION>
                                                                             Shares Beneficially
                                                                                  Owned(1)
                                                                           -----------------------
                                 Name                                         Number      Percent
- ------------------------------------------------------------------------   -----------   ---------
<S>                                                                        <C>             <C>
The Thomas J. Tisch 1999 Annuity Trust I(2)  ...........................     578,100        4.6%
 c/o Mr. Barry Bloom
 667 Madison Avenue
 New York, New York 10021

The Daniel R. Tisch 1999 Annuity Trust I(2)  ...........................     578,100        4.6%
 c/o Mr. Barry Bloom
 667 Madison Avenue
 New York, NY 10021

The James S. Tisch 1999 Annuity Trust I(2)   ...........................     578,100        4.6%
 c/o Mr. Barry Bloom
 667 Madison Avenue
 New York, NY 10021

The Andrew H. Tisch 1999 Annuity Trust I(2)  ...........................     578,100        4.6%
 c/o Mr. Barry Bloom
 667 Madison Avenue
 New York, NY 10021

Four Partners(2)  ......................................................     725,000        5.7%
 c/o Mr. Barry Bloom
 667 Madison Avenue
 New York, NY 10021

Bouybreese & Company/Pebblebay & Co.   .................................     726,045        5.7%
 (Janus Funds)
 100 Fillmore Street
 Denver, CO 80206

K. Michael Forrest(3)   ................................................     940,994        7.2%
 349 Oyster Point Blvd., Suite 200
 South San Francisco, CA 94080

Carl R. Thornfeldt, M.D.(4)   ..........................................     564,786        4.5%
 349 Oyster Point Blvd., Suite 200
 South San Francisco, CA 94080

A. Richard Juelis(5)    ................................................     103,066           *

Larry J. Wells(6)    ...................................................      92,948           *

John J. Chandler(7)  ...................................................      70,500           *

Tobi B. Klar, M.D.(8)   ................................................      62,705           *

Jack L. Bowman(9)    ...................................................      40,585           *

Daniel L. Azarnoff, M.D.(10)  ..........................................      31,000           *

Alan A. Steigrod(11)    ................................................      39,960           *

John W. Dietrich, Ph.D.(12)   ..........................................      17,000           *

Ronald J. Saldarini, Ph.D.(13)   .......................................       7,500           *

All directors and executive officers as a group(14) (11 persons)  ......   5,734,489       32.2%
<FN>
* less than 1%

- ------------

 (1) Based upon  information  supplied  by  officers,  directors  and  principal
     shareholders.  Beneficial  ownership is determined in accordance with rules
     of  the  Securities  and  Exchange   Commission  that  deem  shares  to  be
     beneficially  owned by any  person who has or shares  voting or  investment
     power with respect to such shares. Unless otherwise indicated,  the persons
     named in this table have sole voting

                                       13

<PAGE>

     and sole investing  power with respect to all shares shown as  beneficially
     owned,  subject to  community  property  laws where  applicable.  Shares of
     common  stock  subject  to an  option  that  is  currently  exercisable  or
     exercisable  within 60 days of March 31, 2000 are deemed to be  outstanding
     and to be  beneficially  owned by the person  holding  such  option for the
     purpose of computing  the  percentage  ownership of such person but are not
     treated  as  outstanding  for  the  purpose  of  computing  the  percentage
     ownership of any other person.

 (2) In addition to the  3,037,400  shares of common stock above,  Four-Fourteen
     Partners ("4-14  Partners"),  a Delaware  limited  liability  company,  has
     beneficial  ownership of 47,700 shares of common  stock.  Each of Andrew H.
     Tisch, James R. Tisch, James S. Tisch and Thomas J. Tisch may be deemed (i)
     to  beneficially  own shares owned by the respective  trust listed above of
     which he is trustee and (ii) to have shared beneficial  ownership of shares
     owned by Four Partners and 4-14 Partners.  James S. Tisch also has indirect
     beneficial  ownership of 19,200  shares of common  stock as  custodian  for
     certain accounts of his children.

 (3) Includes 314,167 shares subject to stock options exercisable before May 31,
     2000.

 (4) Excludes  34,823  and  34,726  shares,  respectively, held in trust for two
     relatives   of   Dr.  Thornfeldt.  Includes  170,463  shares  held  by  Dr.
     Thornfeldt's  spouse.  Includes  168,759  shares  subject  to stock options
     exercisable before May 31, 2000.

 (5) Includes 75,066 shares subject to stock options  exercisable before May 31,
     2000.

 (6) Includes 52,707 shares held by Sundance  Venture  Partners,  L.P., of which
     Mr. Wells may be deemed a beneficial owner.  Includes 4,736 shares issuable
     upon  exercise of presently  exercisable  common stock  purchase  warrants.
     Includes 35,505 shares subject to stock options  exercisable before May 31,
     2000.

 (7) Includes 59,500 shares subject to stock options  exercisable before May 31,
     2000.

 (8) Includes 35,505 shares subject to stock options  exercisable before May 31,
     2000.

 (9) Includes 36,085 shares subject to stock options  exercisable before May 31,
     2000.

(10) Includes 31,000 shares subject to stock options  exercisable before May 31,
     2000.

(11) Includes 37,960 shares subject to stock options  exercisable before May 31,
     2000.

(12) Includes 15,000 shares subject to stock options  exercisable  before
     May 31, 2000.

(13) Includes  7,500  shares subject to stock options exercisable before May 31,
     2000.

(14) Includes  52,707  shares  held by Sundance Venture Partners, L.P., of which
     Mr. Wells may be deemed a beneficial owner.  Includes 4,736 shares issuable
     upon  exercise of presently  exercisable  common stock  purchase  warrants.
     Includes 733,547 shares subject to stock options exercisable before May 31,
     2000.
</FN>
</TABLE>
                                       14

<PAGE>

Executive Compensation

<TABLE>
     The following table sets forth all compensation awarded, earned or paid for
services  rendered in all capacities to Cellegy  during fiscal years 1999,  1998
and 1997 to (i) each  person who served as  Cellegy's  chief  executive  officer
during 1999, and (ii) the four most highly  compensated  officers other than the
chief  executive  officer who were serving as  executive  officers at the end of
1999 and whose  total  annual  salary and bonus in such year  exceeded  $100,000
(collectively with the CEO, the "Named Officers").

                           SUMMARY COMPENSATION TABLE
<CAPTION>
                                                                               Long Term
                                              Annual Compensation             Compensation
                                    ---------------------------------------    Securities
    Name and Principal                                     Other Annual        Underlying      All Other
         Position          Year      Salary     Bonus      Compensation         Options       Compensation
- -------------------------- ------   ---------   -------   -----------------   -------------   --------------
                                      ($)        ($)            ($)               (#)             ($)
<S>                        <C>       <C>         <C>           <C>              <C>               <C>
K. Michael Forrest         1999      288,400     --               --            250,000           --
 President and Chief       1998      281,853     --               --            155,000           --
 Executive Officer         1997      261,943     --               --                --            --

Daniel L. Azarnoff, M.D.   1999      120,000     --               --             28,000           --
 VP, Clinical and          1998      115,000     --               --             10,000           --
 Regulatory Affairs        1997       44,747     --               --             50,000           --

John J. Chandler           1999      171,000     --               --             46,500           --
 VP, Corporate             1998      165,000     --            80,000 (1)        90,000           --
 Development               1997          --      --               --                --            --

A. Richard Juelis          1999      170,000     --               --             46,500           --
 VP, Finance and           1998      168,438     --               --                --            --
 Chief Financial Officer   1997      150,000     --               --             16,000           --

John W. Dietrich, Ph.D.    1999      132,500     --            40,000 (1)        90,000           --
 VP, Research and          1998          --      --               --                --            --
 Development               1997          --      --               --                --            --
<FN>
- ------------

(1) Consists of relocation  allowances paid in accordance with their  employment
    agreements.  Relocation allowances were expensed during the period they were
    incurred.
</FN>
</TABLE>

<TABLE>
     The following table sets forth information  regarding  individual grants of
options  to  acquire  Cellegy  common  stock  during  fiscal  1999 to each Named
Officer.

                                               OPTION GRANTS IN LAST FISCAL YEAR
<CAPTION>
                                                                   Individual Grants
                                ---------------------------------------------------------------------------------------
                                                                                                  Potential Realizable
                                  Number of       % of Total                                   Value at Assumed Rates of
                                 Securities        Options          Exercise                   Stock Price Appreciation
                                 Underlying       Granted to           or                          for Option Term(2)
                                  Options         Employees        Base Price    Expiration     -----------------------
             Name                Granted(#)     In Fiscal Year       ($/Sh)         Date          5% ($)      10% ($)
- ------------------------------- ------------   ----------------   ------------   ------------   ---------   -----------
<S>                               <C>                <C>             <C>          <C>            <C>         <C>
K. Michael Forrest(1)    ......    75,000             9.4%           $3.88        01/2009        182,773       463,181
K. Michael Forrest(1)    ......   175,000            21.9%           $3.69        12/2009        406,109     1,029,159
Daniel L. Azarnoff, M.D.    ...    10,500             1.3%           $3.88        01/2009         25,588        64,845
Daniel L. Azarnoff, M.D.    ...    17,500             2.2%           $3.69        12/2009         40,611       102,916
John J. Chandler   ............    21,000             2.6%           $3.88        01/2009         51,176       129,691
John J. Chandler   ............    25,000             3.1%           $3.69        12/2009         58,016       147,023
A. Richard Juelis  ............    24,000             3.0%           $3.88        01/2009         58,487       148,218
A. Richard Juelis  ............    22,500             2.8%           $3.69        12/2009         52,214       132,320
John W. Dietrich, Ph.D.  ......    75,000             9.4%           $5.13        06/2008        241,731       612,595
John W. Dietrich, Ph.D.  ......    15,000             1.9%           $3.69        12/2009         34,809        88,214
<FN>
- ------------

(1) The  exercise  price of all the option  shares shown in the table are at the
    fair market value of the common stock on the grant date.  The shares subject
    to these options become exercisable annually over three years from the grant
    date.

                                       15

<PAGE>

(2) Amounts  represent  hypothetical  gains  that  could  be  achieved  for  the
    respective  options if exercised at the end of the option term.  The assumed
    5% and 10% rates of share price  appreciation  are  mandated by rules of the
    Securities and Exchange  Commission and do not represent  Cellegy's estimate
    or projection of future share prices.
</FN>
</TABLE>

     The  following  table sets forth  information  with  respect to the options
exercised by the Named Officers during fiscal 1999.

              Aggregated Option/SAR Exercises In Last Fiscal Year
                          And FY-End Option/SAR Values

<TABLE>
<CAPTION>
                                                                      Number of Securities            Value of Unexercised
                                                                     Underlying Unexercised               In-The-Money
                                     Shares                              Options/SARs at                   Options at
                                   Acquired on        Value           December 31, 1999 (#)          December 31, 1999 ($)
              Name                Exercise (#)     Realized ($)     Exercisable/Unexercisable     Exercisable/Unexercisable(1)
- --------------------------------- --------------   --------------   ---------------------------   ------------------------------
<S>                                    <C>              <C>              <C>                                <C>
K. Michael Forrest   ............      --               --               289,167/360,833                       *
Daniel L. Azarnoff, M.D.   ......      --               --                27,500/ 60,500                       *
John J. Chandler  ...............      --               --                33,750/102,250                       *
A. Richard Juelis ...............      --               --                97,066/ 49,436                    71,320/*
John W. Dietrich, Ph.D.    ......      --               --                15,000/ 75,000                       *
<FN>
- ------------

(1) Based on the difference between the fair market value of the common stock at
    December 31, 1999 ($3.375 per share) and the exercise price of options shown
    on the table.

*   Exercise  price  is below  the fair  market  value  of the  common  stock at
    December 31, 1999.
</FN>
</TABLE>

Section 16(a) Beneficial Ownership Reporting Compliance

     Section  16(a)  of  the  Exchange  Act  requires  Cellegy's  directors  and
executive  officers,  and persons who own more than ten percent of a  registered
class of  Cellegy's  equity  securities,  to file  with the  Commission  initial
reports of ownership and reports of changes in ownership of Cellegy common stock
and other equity securities of Cellegy. Officers, directors and greater than ten
percent  shareholders  are required by the  Commission's  regulations to furnish
Cellegy  with  copies of all  Section  16(a)  forms  they  filed.  To  Cellegy's
knowledge,  based  solely on review of the copies of such  reports  furnished to
Cellegy,  during the last  fiscal  year all Section  16(a)  filing  requirements
applicable  to  Cellegy's  officers,  directors,  and  greater  than ten percent
beneficial  owners  were  timely  filed,  except that a Form 4 was filed late in
March 2000 with respect to sales, which occured between December 29 and December
31,  1999,  of a total of  31,600  shares of common  stock by  Sundance  Venture
Partners, of which Larry Wells, a director, is general partner.

Compensation Committee Interlocks and Insider Participation

     The  Compensation  Committee  of the  Board  (the  "Committee")  makes  all
decisions involving the compensation of executive officers of Cellegy,  approves
all stock option  grants and  provides  guidance on all other  compensation  and
benefit related issues.

                      REPORT OF THE COMPENSATION COMMITTEE

     This Report of the Compensation  Committee is required by the SEC and shall
not  be  deemed  to be  incorporated  by  reference  by  any  general  statement
incorporating  by  reference  this Proxy  Statement  into any  filing  under the
Securities  Act, or under the  Exchange  Act,  except to the extent that Cellegy
specifically incorporates this information by reference, and shall not otherwise
be deemed soliciting material or filed under such acts.

     Final decisions regarding executive compensation and stock option grants to
executives are made by the Compensation Committee of the Board of Directors (the
"Committee").   The  Committee  is  composed  of  two  independent  non-employee
directors,  none of whom have any  interlocking  relationships as defined by the
SEC.

                                       16

<PAGE>

General Compensation Policy

     The  Committee  acts on  behalf  of the  Board  to  establish  the  general
compensation  policy  of  Cellegy  for all  employees  of  Cellegy.  Subject  to
provisions of any  applicable  employment  agreements,  the Committee  typically
reviews base salary levels and target bonuses for the Chairman,  Chief Executive
Officer ("CEO") and other  executive  officers and employees of Cellegy prior to
the beginning of each fiscal year. The Committee administers Cellegy's incentive
and equity plans,  including the 1995 Equity  Incentive  Plan (the "Plan").  The
Committee's  philosophy  in  compensating  executive  officers,   including  the
Chairman and CEO, is to relate compensation to corporate performance. Consistent
with  this  philosophy,  the  incentive  component  of the  compensation  of the
executive  officers of Cellegy is  contingent  on the  achievement  of corporate
goals and objectives. Long-term equity incentives for executive officers include
the granting of stock options under the Plan. Stock options generally have value
for the executive only if the price of Cellegy's  stock increases above the fair
market value on the grant date and the executive remains in Cellegy's employ for
the  period  required  for the  shares to vest or,  where  vesting of options is
subject to the attainment of certain  performance  objectives,  if the specified
performance objectives are attained.  The base salaries,  incentive compensation
and stock option grants of the executive  officers are determined in part by the
Committee  informally  reviewing  data on prevailing  compensation  practices of
biopharmaceutical  companies with whom Cellegy competes for executive talent and
by their  evaluating  such  information in connection  with Cellegy's  corporate
goals and  objectives.  To this end,  the  Committee  attempted  to compare  the
compensation of Cellegy's executive officers with the compensation  practices of
comparable  companies to determine base salary and total cash  compensation.  In
addition to their base salaries,  Cellegy's  executive  officers,  including the
CEO, are entitled to participate in the Plan. In preparing the performance graph
for this Proxy Statement, Cellegy used The NASDAQ (U.S. only) Stock Market Index
and The  NASDAQ  Pharmaceutical  Stocks  Index as its most  comparable  business
indices.  The  compensation  practices of most of the companies in these indices
were not  reviewed  by Cellegy  when the  Committee  reviewed  the  compensation
information  described  above because such companies  were  determined not to be
competitive with Cellegy for executive talent.

Fiscal 1999 Executive Compensation

     Base  Compensation.   The  Committee  reviewed  the   recommendations   and
performance  and market data outlined above and  established a base salary level
for  each  executive  officer,  including  the  Chairman  and  CEO,  subject  to
provisions of any employment agreements.

     Incentive  Compensation.  Cash  bonuses  may be awarded  if  Cellegy  meets
predetermined corporate goals and objectives set by the Board early in the year.
For fiscal  1999,  the  objectives  used by  Cellegy as the basis for  incentive
compensation for the Chairman, CEO and the other executives were based primarily
on research and clinical development of its products. The target amount of bonus
and  the  actual  amount  of  bonus  are  determined  by the  Committee,  in its
discretion. No cash bonuses were paid for 1999.

     Stock Options. In fiscal 1999, stock options were granted to four executive
officers in addition to the Chairman and CEO:  Dr.  Azarnoff was awarded  28,000
stock options,  Mr. Chandler was awarded 46,000 stock options.  Dr. Dietrich was
awarded  90,000 stock  options upon joining  Cellegy and Mr.  Juelis was awarded
46,500 stock  options.  Stock options  typically  have been granted to executive
officers  when  the  executive  first  joins  Cellegy,   in  connection  with  a
significant  change in  responsibilities  and,  occasionally,  to achieve equity
within a peer group. The Committee may, however,  grant additional stock options
to  executives  for other  reasons.  The number of shares  subject to each stock
option  granted  is  within  the  discretion  of the  Committee  and is based on
anticipated future  contribution and ability to impact corporate and/or business
unit results, past performance or consistency within the executive's peer group.
In fiscal 1999, the Committee considered these factors, as well as the number of
unvested options held by such executive officers as of the date of grant. In the
discretion  of the  Committee,  executive  officers  may also be  granted  stock
options  under  the  Plan  to  provide  greater  incentives  to  continue  their
employment with Cellegy and to strive to increase the value of the common stock.
Initial stock options generally become  exercisable over a four-year period and,
in certain  instances,  sooner based on the  attainment  of certain  objectives.
Annual  stock  option  grants  generally  became  exercisable  over a three-year
period.  All  options  are  granted at a price that is equal to the fair  market
value of the common stock on the date of grant.

                                       17

<PAGE>

     Company  Performance  and  Chairman  and  CEO  Compensation.   Because  Dr.
Thornfeldt and Mr. Forrest were responsible for Cellegy  obtaining a significant
portion  of  its  objectives  for  fiscal  1999,  the  Committee  exercised  its
discretion and  recommended,  during the third quarter of fiscal 1999,  that Mr.
Forrest and Dr.  Thornfeldt  should be granted stock options to purchase 175,000
and 15,000 shares of common stock,  respectively.  In granting  stock options to
Mr. Forrest, the Committee reviewed Mr. Forrest's  achievement of his objectives
including  satisfactorily  managing Cellegy's overall strategic plan, increasing
Cellegy's long-term shareholder valuation by achieving corporate and new product
development  goals,  and  maintaining  a  strong  financial  position.  For  Dr.
Thornfeldt's  compensation,  the Committee  considered his  contributions in the
development of the cosmeceutical product line and in strengthening and expanding
Cellegy's  intellectual  property position and patents.  The Committee  believes
that these grants were  appropriate  because they gave proper  incentives to Dr.
Thornfeldt and Mr. Forrest for fiscal 1999 and future years.  The Committee also
reviewed the compensation  practices of the comparable companies in recommending
these executive grants.

     Compliance  with  Section  162(m)  of the  Internal  Revenue  Code of 1986.
Cellegy  intends  to  comply  with the  requirements  of  Section  162(m) of the
Internal Revenue Code of 1986 for fiscal 2000. The Plan is already in compliance
with Section 162(m).  Cellegy does not expect cash compensation for any employee
in  2000  to  be in  excess  of  $1,000,000  or  consequently  affected  by  the
requirements of Section 162(m).

                                          COMPENSATION COMMITTEE


                                          Jack L. Bowman
                                          Alan A. Steigrod

                                       18

<PAGE>

                         COMPANY STOCK PRICE PERFORMANCE

     The stock  price  performance  graph below is required by the SEC and shall
not  be  deemed  to be  incorporated  by  reference  by  any  general  statement
incorporating  by  reference  this Proxy  Statement  into any  filing  under the
Securities  Act, or under the  Exchange  Act,  except to the extent that Cellegy
specifically incorporates this information by reference, and shall not otherwise
be deemed soliciting material or filed under such acts. The chart below compares
the  cumulative  total  stockholder  return on the common  stock of Cellegy from
August 14, 1995,  the effective  date of Cellegy's  initial  public  offering to
December 31, 1999 with the cumulative total return of The Nasdaq (US only) Stock
Market Index and the NASDAQ Pharmaceutical Stocks Index (assuming the investment
of $100 in Cellegy  common  stock and in each of the indices on August 14, 1995,
and reinvestment of all dividends).  Unless otherwise specified, all dates refer
to the last day of each year presented.

     The graph below compares the  cumulative  total  stockholder  return on the
common stock of Cellegy from August 14, 1995,  the  effective  date of Cellegy's
initial public offering to December 31, 1999 with the cumulative total return of
The Nasdaq (US only) Stock  Market  Index and the NASDAQ  Pharmaceutical  Stocks
Index  (assuming the  investment of $100 in Cellegy  common stock and in each of
the indices on August 14,  1995,  and  reinvestment  of all  dividends).  Unless
otherwise specified, all dates refer to the last day of each year presented.

[The following  descriptive  data is supplied in accordance  with Rule 304(d) of
Regulation S-T]

                     Comparison of Cumulative Total Return

                       8/14/95  12/31/95  12/31/96  12/31/97  12/31/98  12/31/99
                       -------  --------  --------  --------  --------  --------

Cellegy Index           $100      $ 85      $ 75      $140      $ 58      $ 56

Nasdaq Index
  (U.S. Only)           $100      $104      $128      $157      $222      $411

Nasdaq Pharmaceutical
  Index                 $100      $122      $123      $127      $161      $300

Certain Relationships and Related Transactions

     Mr. Forrest, President and Chief Executive Officer and Cellegy entered into
an employment  agreement  dated November 20, 1996. The agreement  provides for a
base  compensation of $265,000 per year. Mr. Forrest's  current annual salary is
$288,400.  Either Cellegy or Mr. Forrest may terminate the agreement at any time
upon notice to the other party.  The agreement  provides that, upon  termination
without cause, Mr. Forrest will be paid twelve months severance and continuation
of  benefits  during the  period  severance  payments  are made.  The  agreement
provides for a grant of 245,000 stock options, 25,000 of which were fully vested
at grant,  and 25,000 of which were vested six months  after the grant date.  An
additional  45,000 shares  subject to the option will vest at the earlier of the
accomplishment of certain milestones or after five years from date of grant. The
remaining 150,000 vest annually over four years from the grant date if there has
been no Employment Termination. As of March 31, 2000, a total of 162,500 options
from his initial grant are vested.

                                       19

<PAGE>

     Dr.  Thornfeldt  and Cellegy  entered  into a  consulting  agreement  dated
February 1, 2000.  The  agreement  provided  for payments of $6,000 per month as
long as Dr. Thornfeldt is devoting at least three business days per month to the
affairs of Cellegy. The agreement included a grant of 100,000 stock options. The
agreement provides for the assignment to Cellegy, subject to certain exclusions,
of  inventions of Dr.  Thornfeldt  during the term of the  agreement.  Under the
Agreement,  he may not  engage  in any  activity  that is  competitive  with the
business of Cellegy,  including without limitation acting as a consultant to any
business that competes,  directly or  indirectly,  with the business of Cellegy.
The  agreement  may be  terminated  before  expiration  of its term upon certain
events,  including Dr. Thornfeldt's death, a material breach of the agreement by
the other party, or by either party upon prior notice.

     Dr.  Azarnoff  became Senior Vice President in July 1999. He joined Cellegy
as Vice  President  of Clinical  and  Regulatory  Affairs in October  1997 after
consulting  with Cellegy on a part-time  basis since January 1997. His agreement
with Cellegy provides for a base  compensation of $120,000 and for certain stock
option grants.  Under the Agreement,  Dr. Azarnoff  devotes 20 hours per week to
Cellegy.

     Dr.  Dietrich became Vice President, Research and Development in June 1999.
His  agreement with Cellegy provides for a base compensation of $185,000 and for
certain stock option grants.

                              SHAREHOLDER PROPOSALS

Advance Notice Procedures for Next Year's Annual Meeting

     Proposals of  shareholders  intended to be  presented  at Cellegy's  Annual
Meeting  of  Shareholders  to be held in 2001 must be  received  in  writing  by
Cellegy's Secretary,  at its principal executive offices, no later than December
10, 2000. In addition,  Cellegy hereby advises  shareholders that, until further
notice,  notice of a  shareholder-sponsored  proposal  submitted  outside of the
process  of Rule  14a-8  under the  Securities  Exchange  Act of 1934  (i.e.,  a
proposal to be presented  at the next annual  meeting of  shareholders,  but not
submitted  for  inclusion  in  Cellegy's  Proxy  Statement)  will be  considered
untimely  under  Cellegy's  bylaws  unless  it is  received  in  writing  by the
Secretary no later than February 28, 2001.

     In  addition,  if Cellegy is not  notified  of a  shareholder  proposal  by
February 28, 2001,  then the proxies held by  management of Cellegy will provide
for  discretionary  authority to vote against such  shareholder  proposal,  even
though such proposal is not discussed in the Proxy Statement.

                                  OTHER MATTERS

     The Board knows of no other  matters  that will be  presented at the Annual
Meeting. If however, any matter is properly presented at the Annual Meeting, the
proxy  solicited  hereby will be voted in  accordance  with the  judgment of the
proxy holders.

                                          By Order of the Board of Directors,


                                          /s/ K. Michael Forrest

                                          K. Michael Forrest
                                          President and Chief Executive Officer

South San Francisco, California


All shareholders  are urged to complete,  sign, date and return the accompanying
Proxy Card in the enclosed postage prepaid  envelope.  Thank you for your prompt
attention to this matter.

                                       20

<PAGE>

1.       ELECTION OF DIRECTORS:

[   ]    FOR all nominees listed            [   ]    WITHHOLD AUTHORITY
         below (except as indicated                  to vote for all nominees
         to the contrary below)                      listed below

NOMINEES: K. Michael Forrest, Carl R. Thornfeldt,  M.D., Jack L. Bowman, Tobi B.
Klar, M.D., Ronald J. Saldarini, Ph.D., Alan A. Steigrod, and Larry J. Wells

INSTRUCTION:  To withhold  authority to vote for any individual  nominee,  write
that nominee's name on the space provided below:

                   ------------------------------------------

2.       APPROVAL OF AMENDEMENT OT THE 1995 EMPLOYEE  INCENTIVE PLAN TO INCREASE
         THE  NUMBER OF  SHARES OF COMMON  STOCK  RESERVED  AND  AUTHORIZED  FOR
         ISSUANCE UNDER THE PLAN BY 1,000,000  SHARES,  FROM 2,450,000 SHARES TO
         3,450,000 SHARES.

         [   ]    FOR               [   ]   AGAINST           [   ]    ABSTAIN

3.       APPROVAL  OF  AMENDMENT  TO THE 1995  DIRECTORS'  STOCK  OPTION PLAN TO
         INCREASE THE NUMBER OF SHARES OF COMMON STOCK  RESERVED AND  AUTHORIZED
         FOR ISSUANCE UNDER THE PLAN BY 100,000  SHARES,  FROM 150,000 SHARES TO
         250,000 SHARES.

          [   ]   FOR               [   ]   AGAINST           [   ]    ABSTAIN

4.       TO RATIFY THE APPOINTMENT OF ERNST & YOUNG LLP AS INDEPENDENT  AUDITORS
         OF THE COMPANY FOR THE 2000 FISCAL YEAR.

         [   ]    FOR               [   ]   AGAINST           [   ]    ABSTAIN

5.       THE  TRANSACTION OF SUCH OTHER BUSINESS AS MAY PROPERLY COME BEFORE THE
         MEETING OR ANY ADJOURNMENTS OR POSTPONEMENTS OF THE MEETING.

         The Board of Directors recommends that you vote FOR the election of all
nominees and FOR Proposal Nos. 2, 3 and 4.

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         THIS  PROXY  WILL  BE  VOTED  AS  DIRECTED  ABOVE.  WHEN NO  CHOICE  IS
INDICATED,  THIS PROXY WILL BE VOTED FOR THE ELECTION OF THE SEVEN  NOMINEES FOR
ELECTION TO THE BOARD OF DIRECTORS  AND FOR  PROPOSAL  NOS. 2, 3 AND 4. In their
discretion, the proxy holders are authorized to vote upon such other business as
may  properly  come  before the  meeting or any  adjournments  or  postponements
thereof  to the  extent  authorized  by  Rule  14a-4(c)  promulgated  under  the
Securities Exchange Act of 1934, as amended.

I PLAN TO ATTEND THE MEETING        [   ]


Dated: ________________, 2000

_____________________________       (Print Shareholder(s) name)

_____________________________       (Signature(s) of Shareholder or
                                    Authorized Signatory)

Please sign as name appears hereon. Joint owners should each sign. If shares are
held of record by a Corporation,  the Proxy should be executed by the president,
vice  president,  secretary  or assistant  secretary.  When signing as attorney,
executor, administrator, trustee or guardian, please give full title as such.

WHETHER  OR NOT YOU PLAN TO  ATTEND  THE  MEETING  IN  PERSON,  YOU ARE URGED TO
COMPLETE,  DATE,  SIGN AND  PROMPTLY  MAIL  THIS  PROXY IN THE  ENCLOSED  RETURN
ENVELOPE SO THAT YOUR SHARES MAY BE REPRESENTED AT THE MEETING.



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