HOUGHTEN PHARMACEUTICALS INC
8-K, 1997-04-25
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                       SECURITIES AND EXCHANGE COMMISSION

                              Washington, DC 20549

                                  -------------

                                    FORM 8-K


                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

         Date of Report (Date of earliest event reported): MAY 1, 1997


                         HOUGHTEN PHARMACEUTICALS, INC.
               (Exact Name of Registrant as Specified in Charter)


   DELAWARE                         0-27972                      51-0336233
(State or Other                   (Commission                  (IRS Employer
Jurisdiction of                   File Number)               Identification No.)
Incorporation)


3550 GENERAL ATOMICS COURT, SAN DIEGO, CA                          92121
(Address of Principal Executive Offices)                         (Zip Code)


                                 (619) 455-3814
              (Registrant's telephone number, including area code)
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ITEM 5.    CORPORATE NAME CHANGE.


         Effective May 1, 1997, Houghten Pharmaceuticals, Inc., a Delaware
corporation ("HPI"), is changing its corporate name to the following:


                            "Trega Biosciences, Inc."


Article I of the Restated Certificate of Incorporation of HPI will be amended,
effective May 1, 1997, to read as follows:

         "The name of the corporation is Trega Biosciences, Inc."

         The foregoing description of the name change and related transactions
is qualified in its entirety by reference to a Certificate of Ownership and
Merger which has been filed with the Delaware Secretary of State, a copy of
which is included as an exhibit to this Form 8-K and incorporated herein by this
reference. The press release of HPI dated April 15, 1997, announcing the name
change, is also included as an exhibit to this Form 8-K and incorporated herein
by this reference.

         (a)      EXHIBITS.

         1.       Certificate of Ownership and Merger.

         2.       Press Release of April 15, 1997.


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                                    SIGNATURE


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


         Dated:  April 23, 1997


                                            HOUGHTEN PHARMACEUTICALS, INC.



                                            By /s/ Terence E. McMorrow
                                               -------------------------------
                                               Terence E. McMorrow
                                               Vice President, Finance and
                                               Corporate Development


                                       -3-
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                                  Exhibit Index


Exhibit
Number                             Description
- -------                            -----------

1.       Certificate of Ownership and Merger dated April 8, 1997 and filed with
         the Delaware Secretary of State on April 18, 1997.

2.       Press Release of April 15, 1997.


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<PAGE>   1
                                   EXHIBIT 1

                      CERTIFICATE OF OWNERSHIP AND MERGER

                                    MERGING

                              HPITBI MERGER CORP.

                                      INTO

                         HOUGHTEN PHARMACEUTICALS, INC.

                        (Pursuant to Section 253 of the
                      General Corporation Law of Delaware)

                         TO BE EFFECTIVE ON MAY 1, 1997

         Houghten Pharmaceuticals, Inc., a corporation organized and existing
under the laws of Delaware (the "CORPORATION"), does hereby certify:

                  FIRST:  That the Corporation owns all of the outstanding
         shares of each class of stock of HPITBI Merger Corp., a Delaware
         corporation.

                  SECOND: That the Corporation, by the following resolutions of
         its Board of Directors, duly adopted at a meeting held on February 25,
         1997, determined to and did merge into itself (to be effective on May
         1, 1997) said HPITBI Merger Corp. by the adoption thereof:

                           RESOLVED, that the Corporation (i) merge, and it
                  hereby does merge, into itself HPITBI Merger Corp. and (ii)
                  assume all of the obligations of HPITBI Merger Corp.

                           RESOLVED, that said merger shall become effective ON
                  MAY 1, 1997.

                           RESOLVED, that upon the effectiveness of said merger,
                  the name of the Corporation shall be changed to the following:

                           "TREGA BIOSCIENCES, INC."

                  and Article I of the Restated Certificate of Incorporation of
                  the Corporation, as heretofore amended, shall be amended to
                  read as follows:

                                    "THE NAME OF THE CORPORATION IS TREGA
                           BIOSCIENCES, INC."


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<PAGE>   2
                           RESOLVED, that except for the foregoing amendment to
                  Article I, the Restated Certificate of Incorporation of the
                  Corporation, as heretofore amended, shall remain unchanged by
                  the merger and in full force and effect until further amended
                  in accordance with the Delaware General Corporation Law.

                           RESOLVED, that the proper officers of the Corporation
                  be, and they hereby are, directed to make and execute a
                  Certificate of Ownership and Merger setting forth a copy of
                  the resolutions to so merge HPITBI Merger Corp. and to assume
                  its obligations, and to so change the name of the Corporation,
                  and the date of adoption thereof, and to cause the same to be
                  filed with the Secretary of State of the State of Delaware,
                  and to do all acts and things whatsoever, whether within or
                  without the State of Delaware, which may be necessary or
                  proper to effect said merger and name change.


         In witness whereof, the Corporation has caused this Certificate to be
signed by its duly authorized officers this 8th day of April, 1997.

                                             Houghten Pharmaceuticals,
                                             Inc., a Delaware corporation



                                         By:  /s/  Robert S. Whitehead
                                             ----------------------------
                                             Robert S. Whitehead
                                             Chief Executive Officer and
                                             President


                                         By:  /s/  Terence E. McMorrow
                                             ----------------------------
                                             Terence E. McMorrow
                                             Vice President, Finance and
                                             Corporate Development, and
                                             Secretary


                                       -6-

<PAGE>   1
                                    EXHIBIT 2


                                              CONTACT:
                                              Noel M. Byczek
                                              Director, Corporate Communications
                                              (619) 455-2877


FOR IMMEDIATE RELEASE


                   HOUGHTEN PHARMACEUTICALS TO CHANGE NAME TO
                             TREGA BIOSCIENCES, INC.
               The Company Will Trade Under The Nasdaq Symbol TRGA


SAN DIEGO, Calif., -- April 15, 1997 -- Houghten Pharmaceuticals, Inc. (HPI)
(Nasdaq:HPIP) today announced that effective May 1, 1997 the company will
undergo a name change to Trega Biosciences, Inc. (tray-ga) and it will trade on
the Nasdaq Stock Market under the symbol TRGA. The company will also re-launch
its corporate web site at http:\\www.trega.com.

"Our name change represents our continuing transition from a single-technology
company into a drug discovery organization with greater technology depth,"
stated Robert S. Whitehead, HPI's president and chief executive officer. "Our
new name and symbol represent the ideal combination of technology, people and
partnerships, and will better suit us as we continue working to become a fully
integrated resource for accelerated discovery of potential human
pharmaceuticals."

HPI (soon to be Trega Biosciences) is a drug discovery company, utilizing
combinatorial chemistry and other technologies to pursue the discovery of novel,
small-molecule drug therapies. The company leverages its technology platform by
entering into pharmaceutical alliances, enabling partners to access HPI's
technologies in exchange for licensing fees and potential milestone payments and
royalties, or by establishing joint-discovery alliances with biotechnology
companies. HPI also uses its drug discovery technologies in its internal
development programs. HP 228, the company's lead compound, is in Phase II trials
for the treatment of inflammatory and metabolic diseases.


                                   -- more --


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Except for the historical information contained herein, the matters discussed in
this news release are forward-looking statements that involve risks and
uncertainties, including whether any proposed product can be successfully
formulated, scaled-up, developed and commercialized, whether regulatory
approvals can be obtained, the impact of competitive products and pricing,
whether any corporate collaborations or alliances will be successful, and other
risks detailed from time to time in HPI's Securities and Exchange Commission
(SEC) filings. These forward-looking statements represent HPI's judgment as of
the date of this release. Actual results may differ materially from those
projected. HPI disclaims, however, any intent or obligation to update these
forward-looking statements.


                                       ###


HPI's releases are on the World Wide Web at http://www.houghten.com and PR
Newswire's fax-on-demand service at 1-800-758-5804, extension 374050.


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