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EXHIBIT 23.1
CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS
We consent to the reference to our firm under the caption "Experts"
in this Registration Statement on Form S-3/A and related Prospectus of Trega
Biosciences, Inc. for the registration of 3,886,668 shares of its common
stock and to the incorporation by reference therein of our report dated
January 27, 2000, with respect to the consolidated financial statements of
Trega Biosciences, Inc. included in its Annual Report (Form 10-K) for the
year ended December 31, 1999, filed with the Securities and Exchange
Commission.
/s/ ERNST & YOUNG LLP
San Diego, California
July 24, 2000
