DEAN WITTER HEALTH SCIENCES TRUST
N-30D, 1997-09-29
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<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
Two World Trade Center, New York, New York 10048 
LETTER TO THE SHAREHOLDERS July 31, 1997 

DEAR SHAREHOLDER: 

During the fiscal year ended July 31, 1997, the stock market continued to 
soar with the Dow Jones Industrial Average gaining 51.75 percent. Large-cap 
stocks continued to lead the market; however, in May, the Russell 2000 Index 
began showing signs of strength. For the period under review, the Russell 
2000 gained 33.39 percent. 

PERFORMANCE AND PORTFOLIO STRATEGY 


[THE NARRATIVE AND/OR TABULAR INFORMATION BELOW IS A FAIR AND ACCURATE
DESCRIPTION OF GRAPHIC OR IMAGE MATERIAL OMITTED FOR THE PURPOSE OF EDGAR
FILING.]

GROWTH OF $10,000
- --------------------------------------------------------------------------
($ IN THOUSANDS)

DATE                   FUND            S&P 500(4)       LIPPER(5)

October 30, 1992       $10,000         $10,000          $10,000
July 31, 1993          $ 9,220         $10,932          $ 9,437
July 31, 1994          $ 9,320         $11,496          $10,253
July 31, 1995          $12,880         $14,489          $13,881
July 31, 1996          $16,079         $16,881          $16,456
July 31, 1997          $17,093(3)      $25,674          $21,972

AVERAGE ANNUAL TOTAL RETURNS (FUND)

     ONE YEAR          LIFE OF FUND
      7.55 (1)          12.22 (1)
      2.55 (2)          11.95 (2)

Past performance is not predictive of future returns.

(1)     Figure shown does not reflect any sales charges.

(2)     Figure shown assumes the deduction of the maximum applicable
        contingent deferred sales charge (CDSC) (1 year-5%, since 
        inception-2%). See the Fund's current prospectus for complete
        details on fees and sales charges.
      
(3)     Closing value after the deduction of a 2% CDSC assuming a complete
        redemption on July 31, 1997.

(4)     The Standard & Poor's 500 Composite Stock Price Index (S&P 500) is
        a broad-based index, the performance of which is based on the average
        performance of 500 widely held common stocks. The index does not 
        include any expenses, fees or charges. The index is unmanaged and 
        should not be considered an investment.

(5)     The Lipper Health/Biotechnology Funds Index is an equally-weighted 
        performance index of the largest qualifying funds (based on net assets) 
        in the Lipper Health/Biotechnology Funds objective. The index, which is 
        adjusted for capital gains distributions and income dividends, is 
        unmanaged and should not be considered for investment. There are 
        currently 10 funds represented in this index.

As of July 28, 1997, the Fund began offering four classes of shares: A, B, C 
and D, each with its own sales charge and distribution fee structure. Fund 
shares held prior to July 28 were designated Class B shares. A revised 
prospectus, which includes complete details regarding the Fund's conversion 
to multiple classes of shares, was mailed to shareholders in mid-summer. 

For the fiscal year ended July 31, 1997, Dean Witter Health Sciences Trust 
(Class B) produced a total return of 7.55 percent compared to 52.08 percent 
for the broad-based Standard & Poor's 500 Composite Stock Index (S&P 500) and 
33.52 percent for the Lipper Health/Biotechnology Funds Index. The accompanying
chart illustrates the performance of Class B shares of the Fund versus the 
performance of similar hypothetical investments in the S&P 500 and the Lipper 
Index. 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
LETTER TO THE SHAREHOLDERS July 31, 1997, continued 

The Fund's small-cap healthcare holdings negatively impacted the Fund's 
performance. These stocks were hindered during the first half of the fiscal 
year by concerns over rising interest rates and an inflationary environment 
following the release of some controversial economic data and the Federal 
Reserve Board's 25 basis point rate hike in March. However, investor 
sentiment has recently warmed considerably toward these smaller companies in 
healthcare, mirroring an apparent trend in the broader market. 

The Fund's large-cap holdings, such as Warner Lambert Co., Baxter 
International Inc. and Pharmacia Upjohn Inc., contributed positively to the 
Fund's performance. A few of these large companies are on the brink of 
developing a new class of cholesterol-reducing drugs. This good news has led 
to a favorable earnings outlook for the group and increasingly high investor 
sentiment. 

During the period under review, the Fund remained well diversified among 
different sectors within the healthcare industry. On July 31, 1997, 
pharmaceuticals made up 16.9 percent of the Fund's portfolio, biotechnology 
made up 18.9 percent, and medical products and supplies made up 15.5 percent. 
The Fund's five largest sectors on July 31, 1997, were biotechnology, 
pharmaceuticals, medical products and supplies, diversified healthcare and 
drugs. At the end of the period under review, the Fund's net assets totaled 
$422.7 million. 

LOOKING AHEAD 

Over the near term, we expect that large-cap pharmaceutical stocks will 
continue to perform well and will continue to attract investor attention and 
support. Over the longer term, however, we believe that the small-and mid-cap 
names in healthcare that the Fund focuses on are positioned to outperform 
their large-cap counterparts. Overall, the fundamentals of the healthcare 
industry bode well for the Fund's future performance. 

We appreciate your support of Dean Witter Health Sciences Trust and look 
forward to continuing to serve your financial needs and objectives. 

Very truly yours, 

/s/ Charles A. Fiumefreddo 
CHARLES A. FIUMEFREDDO 
Chairman of the Board 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
RESULTS OF SPECIAL MEETING (unaudited) 

                                    * * * 

On May 21, 1997, a special meeting of shareholders of Dean Witter Health 
Sciences Trust was held for the purpose of voting on four separate matters, 
the results of which are as follows: 

(1) APPROVAL OF A NEW INVESTMENT MANAGEMENT AGREEMENT BETWEEN THE FUND AND 
DEAN WITTER INTERCAPITAL INC. IN CONNECTION WITH THE MERGER OF MORGAN STANLEY 
GROUP INC. WITH DEAN WITTER, DISCOVER & CO.: 

<TABLE>
<CAPTION>
 <S>           <C>
 For .......  15,245,200 
 Against  ..     468,085 
 Abstain  ..   1,286,925 
</TABLE>

(2) ELECTION OF TRUSTEES: 

<TABLE>
<CAPTION>
<S>                      <C>
Michael Bozic 
For ...................  16,002,890 
Withheld ..............     997,320 

Charles A. Fiumefreddo 
For ...................  15,997,443 
Withheld ..............   1,002,767 

Edwin J. Garn 
For ...................  16,009,570 
Withheld ..............     990,640 

 John R. Haire 
 For ..................  15,967,947 
 Withheld .............   1,032,263 

 Wayne E. Hedien 
 For ..................  15,988,706 
 Withheld .............   1,011,504 

 Dr. Manuel H. Johnson 
 For ..................  16,001,709 
 Withheld .............     998,501 

 Michael E. Nugent 
 For ..................  16,021,959 
 Withheld .............     978,251 

 Philip J. Purcell 
 For ..................  16,016,109 
 Withheld .............     984,101 

 John L. Schroeder 
 For ..................  15,989,962 
 Withheld .............   1,010,248 
</TABLE>

(3) APPROVAL OF A NEW INVESTMENT POLICY WITH RESPECT TO INVESTMENTS IN 
    CERTAIN OTHER INVESTMENT COMPANIES: 

<TABLE>
<CAPTION>
  <S>          <C>
  For ......  14,586,239 
  Against  .     822,025 
  Abstain  .   1,591,946 
</TABLE>

(4) RATIFICATION OF THE SELECTION OF PRICE WATERHOUSE LLP AS THE FUND'S 
INDEPENDENT ACCOUNTANTS: 

<TABLE>
<CAPTION>
  <S>         <C>
  For .....  15,637,752 
  Against       272,099 
  Abstain     1,090,359 
</TABLE>

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997 

<TABLE>
<CAPTION>
 NUMBER OF 
SHARES                                                                           VALUE 
- --------------------------------------------------------------------------- --------------- 
<S>        <C>                                                              <C>
           COMMON STOCKS (98.5%) 
           Biotechnology (18.9%) 
 100,000   Affymetrix, Inc.* ...............................................  $ 3,237,500 
 120,000   Agouron Pharmaceutical, Inc.* ...................................   11,490,000 
 150,000   Alexion Pharmaceuticals, Inc.* ..................................    1,556,250 
 200,000   Alkermes, Inc.* .................................................    3,125,000 
 100,000   Arterial Vascular Engineering, Inc.* ............................    3,825,000 
  30,000   Aviron* .........................................................      810,000 
 100,000   Biochem Pharma, Inc. (Canada)* ..................................    2,875,000 
 170,000   Biomatrix, Inc. .................................................    3,825,000 
  50,000   Biomira, Inc (Canada)* ..........................................      219,457 
 100,000   Cell Therapeutics, Inc.* ........................................    1,337,500 
 100,000   Centocor, Inc.* .................................................    3,843,750 
 170,000   Genzyme Corp. General Division* .................................    4,632,500 
   5,100   Genzyme Corp. Tissue Repair Division* ...........................       54,825 
 150,000   Gilead Sciences, Inc.* ..........................................    4,218,750 
 200,000   IDEC Pharmaceuticals Corp.* .....................................    5,462,500 
 150,000   Immunex Corp.* ..................................................    5,718,750 
 100,000   Interferon Sciences, Inc.* ......................................      631,250 
 100,000   Ligand Pharmaceuticals, Inc. (Class B)* .........................    1,262,500 
 100,000   Matritech, Inc.* ................................................      568,750 
  76,000   Maxim Pharmaceuticals, Inc. .....................................      722,000 
  80,000   Neurex Corp.* ...................................................      990,000 
 100,000   Neurogen Corp.* .................................................    2,175,000 
  30,000   OEC Medical Systems, Inc.* ......................................      513,750 
 140,000   Protein Design Labs, Inc.* ......................................    3,902,500 
  25,000   Ribi ImmunoChem Research, Inc.* .................................       96,875 
 150,000   Sepracor, Inc.  .................................................    3,768,750 
  40,000   Transcend Therapeutics, Inc.* ...................................      360,000 
 150,000   Vertex Pharmaceuticals, Inc.* ...................................    5,231,250 
 200,000   Vion Pharmaceuticals, Inc.* .....................................      812,500 
 200,000   Virus Research Institute, Inc.  .................................    1,250,000 
  40,000   Zonagen, Inc.* ..................................................    1,170,000 
                                                                            --------------- 
                                                                               79,686,907 
                                                                            --------------- 
           Commercial Services (3.4%) 
 140,000   Advanced Health Corp.  ..........................................    2,590,000 
  40,000   Complete Management, Inc.  ......................................      597,500 
 150,000   Equity Corporation International* ...............................    3,609,375 
 100,000   Medquist, Inc.* .................................................    3,250,000 
 100,000   Stewart Enterprises, Inc. (Class A) .............................    4,325,000 
                                                                            --------------- 
                                                                               14,371,875 
                                                                            --------------- 
           Computer Software (1.6%) 
 130,000   Cerner Corp.* ...................................................    3,900,000 
 100,000   Medic Computer Systems, Inc.* ...................................    2,700,000 
                                                                            --------------- 
                                                                                6,600,000 
                                                                            --------------- 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997, continued 

NUMBER OF 
SHARES                                                                           VALUE 
- --------------------------------------------------------------------------- --------------- 
           Computer Software & Services (1.3%) 
 100,000   A.L.I. Technologies Inc. (Canada)* ..............................  $   805,281 
  50,000   Daou Systems, Inc.* .............................................      987,500 
  60,000   HPR Inc.* .......................................................      945,000 
  50,000   ImageMatrix Corp. (Units)++* ....................................      114,062 
  50,000   Imnet Systems, Inc. .............................................    1,737,500 
 100,000   Sunquest Information Systems, Inc.* .............................    1,087,500 
                                                                            --------------- 
                                                                                5,676,843 
                                                                            --------------- 
           Consumer Products (0.5%) 
  20,000   Chattem, Inc.* ..................................................      345,000 
 100,000   Perrigo Co.* ....................................................    1,300,000 
  50,000   Selfcare, Inc.* .................................................      600,000 
                                                                            --------------- 
                                                                                2,245,000 
                                                                            --------------- 
           Drugs (7.6%) 
  35,000   Ascent Pediatrics, Inc.* ........................................      253,750 
 160,000   Columbia Laboratories, Inc.  ....................................    3,150,000 
 220,000   Dura-Pharmaceuticals, Inc.* .....................................    8,538,750 
 150,000   Elan Corp. PLC (ADR)(Ireland)* ..................................    7,125,000 
 110,000   Glaxo Wellcome PLC (ADR)(United Kingdom) ........................    4,675,000 
 180,000   ICN Pharmaceuticals, Inc. .......................................    6,153,750 
 100,000   Labopharm Inc. (Canada)* ........................................      272,055 
  50,000   Pharmacia & Upjohn, Inc.  .......................................    1,887,500 
                                                                            --------------- 
                                                                               32,055,805 
                                                                            --------------- 
           Finance (0.3%) 
  55,000   HealthCare Financial Partners, Inc.  ............................    1,168,750 
                                                                            --------------- 
           Health Equipment & Services (5.2%) 
 100,000   Diagnostic Health Services, Inc.* ...............................    1,100,000 
  60,000   Medtronic, Inc.  ................................................    5,235,000 
 197,400   Renal Treatment Centers, Inc.* ..................................    5,823,300 
 270,000   RoTech Medical Corp.* ...........................................    5,028,750 
 120,000   Sabratek Corp.* .................................................    3,225,000 
 158,000   Vista Medical Technologies, Inc.* ...............................    1,422,000 
                                                                            --------------- 
                                                                               21,834,050 
                                                                            --------------- 
           Healthcare (0.8%) 
 110,000   Allegiance Corp. ................................................    3,437,500 
                                                                            --------------- 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997, continued 

NUMBER OF 
SHARES                                                                           VALUE 
- --------------------------------------------------------------------------- --------------- 
           Healthcare -Diversified (8.2%) 
 280,000   Healthsouth Corp.* ..............................................  $ 7,420,000 
  50,000   Humana, Inc.* ...................................................    1,218,750 
 100,000   Integrated Health Services, Inc.  ...............................    3,412,500 
 150,000   Mentor Corp.  ...................................................    4,603,125 
 150,000   NovaCare, Inc.* .................................................    1,940,625 
  34,200   Simione Center Holdings, Inc.* ..................................      342,000 
 150,000   Universal Health Services, Inc. (Class B)* ......................    6,093,750 
  70,000   Warner-Lambert Co.  .............................................    9,778,125 
                                                                            --------------- 
                                                                               34,808,875 
                                                                            --------------- 
           Hospital Management & Health 
             Maintenance Organizations (0.8%) 
 100,000   American Oncology Resources, Inc.* ..............................    1,525,000 
  40,000   Healthcare Recoveries, Inc.* ....................................      730,000 
  80,000   Specialty Care Network, Inc.* ...................................      970,000 
                                                                            --------------- 
                                                                                3,225,000 
                                                                            --------------- 
           Hospital Management (6.1%) 
 100,000   American HomePatient, Inc.* .....................................    1,975,000 
 170,000   FPA Medical Management, Inc.  ...................................    4,505,000 
 100,000   Genesis Health Ventures, Inc.* ..................................    3,387,500 
  50,000   Harborside Healthcare Corp.  ....................................      806,250 
  50,000   Impath, Inc.* ...................................................    1,312,500 
  25,000   Pediatric Services of America, Inc.* ............................      562,500 
  60,000   Quorum Health Group, Inc.* ......................................    2,137,500 
 180,000   Renal Care Group, Inc.* .........................................    5,152,500 
 120,000   Tenet Healthcare Corp.* .........................................    3,592,500 
  60,000   Total Renal Care Holdings, Inc.* ................................    2,475,000 
                                                                            --------------- 
                                                                               25,906,250 
                                                                            --------------- 
           Hospital Supply (0.2%) 
  98,800   Boston Biomedica, Inc.  .........................................      679,250 
                                                                            --------------- 
           Insurance (0.5%) 
  50,000   Guaranty National Corp.  ........................................    1,331,250 
  47,300   Summit Holding Southeast Inc.* ..................................      886,875 
                                                                            --------------- 
                                                                                2,218,125 
                                                                            --------------- 
           Life Insurance (0.9%) 
  70,000   CRA Managed Care, Inc.* .........................................    3,587,500 
                                                                            --------------- 
           Manufacturing (0.3%) 
  35,000   Axogen Ltd. (Units)++ ...........................................    1,150,625 
                                                                            --------------- 
           Medical Products & Supplies (15.5%) 
  20,000   Abiomed, Inc.* ..................................................      325,000 
 100,000   ArQule, Inc.* ...................................................    1,650,000 
 100,000   Bard (C.R.), Inc.  ..............................................    3,762,500 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997, continued 

NUMBER OF 
SHARES                                                                           VALUE 
- --------------------------------------------------------------------------- --------------- 
 110,000   Baxter International, Inc.  .....................................  $ 6,359,375 
  60,000   Closure Medical Corp.* ..........................................    1,605,000 
  40,000   Cooper Companies, Inc.* .........................................    1,120,000 
  90,000   Cryolife, Inc.* .................................................    1,119,375 
  83,100   EP MedSystems, Inc.  ............................................      228,525 
  70,000   Guidant Corp.  ..................................................    6,387,500 
 100,000   Hanger Orthopedic Group, Inc.* ..................................    1,275,000 
  30,000   Health Care & Retirement Corp.* .................................    1,072,500 
  25,000   Healthdyne Technologies, Inc.* ..................................      421,875 
  50,000   Intelligent Medical Imaging, Inc.* ..............................      331,250 
  50,000   IRIDEX Corp.* ...................................................      493,750 
 150,000   Kinetic Concepts, Inc. ..........................................    2,812,500 
  80,000   Laser Industries, Ltd. ..........................................    1,380,000 
 100,000   Lincare Holdings, Inc.* .........................................    4,900,000 
 100,000   Molecular Dynamics, Inc.* .......................................    2,050,000 
  40,000   Sight Resource Corp. (Units)++* .................................      215,000 
 100,000   Novoste Corp.  ..................................................    1,575,000 
 100,000   Osteotech, Inc.* ................................................    1,275,000 
  20,000   Penederm, Inc.* .................................................      232,500 
 110,000   Perclose, Inc.* .................................................    2,530,000 
 110,000   PLC Systems, Inc. (Canada)* .....................................    1,436,875 
 100,000   ResMed, Inc.  ...................................................    2,400,000 
 100,000   Spine-Tech, Inc* ................................................    5,900,000 
  40,000   Sterile Recoveries, Inc.* .......................................      615,000 
  60,000   TECNOL Medical Products, Inc.* ..................................    1,320,000 
 100,000   Urologix, Inc.  .................................................    1,762,500 
 120,000   Ventana Medical Systems, Inc.* ..................................    1,995,000 
 240,000   Vivus, Inc.* ....................................................    7,170,000 
                                                                            --------------- 
                                                                               65,721,025 
                                                                            --------------- 
           Medical Services (6.5%) 
 110,000   Alternative Living Services, Inc.  ..............................    2,371,875 
  30,000   Coventry Corp.* .................................................      530,625 
  70,000   EndoSonics Corp.* ...............................................      927,500 
  45,790   HBO & Co.  ......................................................    3,537,278 
 140,000   Medical Resources, Inc.* ........................................    2,240,000 
 100,000   Quintiles Transnational Corp.* ..................................    7,500,000 
  50,000   Sheridan Healthcare, Inc.* ......................................      618,750 
 160,000   Transkaryotic Therapies, Inc.  ..................................    5,600,000 
 100,000   Vencor, Inc.* ...................................................    4,031,250 
                                                                            --------------- 
                                                                               27,357,278 
                                                                            --------------- 
           Miscellaneous (0.0%) 
   5,600   Corsair Communications, Inc.* ...................................      109,900 
   5,000   Monarch Dental Corp.* ...........................................       87,500 
                                                                            --------------- 
                                                                                  197,400 
                                                                            --------------- 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997, continued 

NUMBER OF 
SHARES                                                                           VALUE 
- --------------------------------------------------------------------------- --------------- 
           Pharmaceuticals (16.9%) 
 120,000   Andrx Corp.  ....................................................  $  3,960,000 
 100,000   Aronex Pharmaceuticals, Inc.* ...................................       437,500 
  70,000   Biovail Corporation International* ..............................     1,872,500 
 180,000   Bone Care International, Inc.* ..................................     2,790,000 
  60,000   Cadus Pharmaceutical Corp.  .....................................       817,500 
  50,000   ChiRex, Inc.* ...................................................       856,250 
 100,000   Coulter Pharmaceutical, Inc.  ...................................       812,500 
 100,000   Curative Health Services, Inc.* .................................     3,137,500 
 220,000   Cypros Pharmaceutical Corp.* ....................................       893,750 
  70,000   DUSA Pharmaceuticals, Inc.* .....................................       358,750 
 150,000   Emisphere Technologies, Inc.* ...................................     2,906,250 
  80,000   Genset (ADR)(France)* ...........................................     2,000,000 
 350,000   Guilford Pharmaceuticals, Inc.* .................................     7,743,750 
  50,000   Hyal Pharmaceutical Corp. (Canada) ..............................       139,655 
 120,000   ICOS Corp.* .....................................................     1,035,000 
 120,000   Incyte Pharmaceuticals, Inc.* ...................................     8,115,000 
 120,000   Inhale Therapeutic Systems* .....................................     2,925,000 
  90,000   Kos Pharmaceuticals, Inc.* ......................................     3,487,500 
 140,000   Medicis Pharmaceutical Corp. (Class A)* .........................     6,300,000 
 100,000   OrthoLogic Corp.* ...............................................       631,250 
 220,000   Parexel International Corp. .....................................     8,470,000 
 120,000   PathoGenesis Corp.* .............................................     3,480,000 
  50,000   Salix Holdings, Ltd. (Canada)* ..................................       304,701 
 180,000   Sangstat Medical Corp.* .........................................     4,342,500 
  70,000   Watson Pharmaceuticals, Inc.* ...................................     3,465,000 
                                                                            --------------- 
                                                                                71,281,856 
                                                                            --------------- 
           Retail--Specialty (1.7%) 
 120,000   Cole National Corp. (Class A)* ..................................     5,182,500 
  35,368   CVS Corp. .......................................................     2,011,555 
                                                                            --------------- 
                                                                                 7,194,055 
                                                                            --------------- 
           Specialized Services (0.3%) 
  40,000   Service Corp. International .....................................     1,360,000 
                                                                            --------------- 
           Wholesale Distributor (1.0%) 
  50,000   McKesson Corp.  .................................................     4,334,375 
                                                                            --------------- 
           TOTAL COMMON STOCKS 
           (Identified Cost $304,444,915) ..................................   416,098,344 
                                                                            --------------- 
</TABLE>

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
PORTFOLIO OF INVESTMENTS July 31, 1997, continued 

<TABLE>
<CAPTION>
NUMBER OF 
WARRANTS                                                                              VALUE 
- ------------------------------------------------------------------------------------------------ 
<S>            <C>                                                              <C>
               WARRANTS (0.0%) 
               Pharmaceuticals 
    30,000     SuperGen, Inc. (due 03/12/01)* 
               (Identified Cost $43,448) .......................................    $ 195,000 
                                                                                ---------------- 
</TABLE>

<TABLE>
<CAPTION>
 PRINCIPAL 
 AMOUNT IN 
 THOUSANDS 
- ----------- 
<S>          <C>                                                              <C>
             SHORT-TERM INVESTMENT (1.0%) 
             REPURCHASE AGREEMENT 
             The Bank of New York 5.75%  due 08/01/97 (dated 07/31/97; 
              proceeds $4,393,616)(a) 
   $4,393     (Identified Cost $4,392,915) ...................................  4,392,915 
                                                                              ------------ 
</TABLE>

<TABLE>
<CAPTION>
<S>                                 <C>       <C>
TOTAL INVESTMENTS 
(Identified Cost $308,881,278)(b) .    99.5%    420,686,259 
OTHER ASSETS IN EXCESS OF 
LIABILITIES........................   0.5         2,020,805 
                                    --------- ------------- 
NET ASSETS.........................   100.0%   $422,707,064 
                                    ========= ============= 
</TABLE>

- ------------ 
ADR     American Depository Receipt. 
  *     Non-income producing security. 
 ++     Consists of more than one class of securities traded together as a 
        unit; stocks with attached warrants. 
(a)     Collateralized by $1,117,580 Federal Home Loan Banks 6.10% due 
        11/27/98 valued at $1,130,080, $1,341,872 Federal National Mortgage 
        Assoc. 6.15% due 12/14/01 valued at $1,339,470 and $2,000,000 Federal 
        National Mortgage Assoc. 8.13% due 07/08/11 valued at $2,011,223. 
(b)     The aggregate cost for federal income tax purposes approximates 
        identified cost. The aggregate gross unrealized appreciation is 
        $119,250,992 and the aggregate gross unrealized depreciation is 
        $7,446,011, resulting in net unrealized appreciation of $111,804,981. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL STATEMENTS 

STATEMENT OF ASSETS AND LIABILITIES 
July 31, 1997 

<TABLE>
<CAPTION>
<S>                                                                <C>
 ASSETS: 
Investments in securities, at value (identified cost 
 $308,881,278)....................................................    $420,686,259 
Receivable for: 
  Investments sold................................................       5,813,979 
  Shares of beneficial interest sold..............................         437,522 
  Dividends.......................................................          74,215 
Deferred organizational expenses..................................           8,034 
Prepaid expenses and other assets.................................          16,656 
                                                                   -------------- 
  TOTAL ASSETS ...................................................     427,036,665 
                                                                   -------------- 
LIABILITIES: 
Payable for: 
  Investments purchased...........................................       2,886,868 
  Shares of beneficial interest repurchased.......................         624,067 
  Investment management fee.......................................         357,582 
  Plan of distribution fee........................................         357,581 
Accrued expenses and other payables ..............................         103,503 
                                                                   ---------------
  TOTAL LIABILITIES...............................................       4,329,601 
                                                                   ---------------
  NET ASSETS......................................................    $422,707,064 
                                                                   ===============
COMPOSITION OF NET ASSETS: 
Paid-in-capital...................................................     307,533,850 
Net unrealized appreciation ......................................     111,804,981 
Accumulated net investment loss...................................         (32,076) 
Accumulated undistributed net realized gain.......................       3,400,309 
                                                                   ---------------
  NET ASSETS .....................................................    $422,707,064 
                                                                   ===============
CLASS A SHARES: 
Net Assets........................................................         $10,069 
Shares Outstanding (unlimited authorized, $.01 par value) ........             667 
  NET ASSET VALUE PER SHARE.......................................          $15.10 
                                                                   ===============
  MAXIMUM OFFERING PRICE PER SHARE 
   (net asset value plus 5.54% of net asset value)................          $15.94 
                                                                   ===============
CLASS B SHARES: 
Net Assets........................................................    $422,666,859 
Shares Outstanding (unlimited authorized, $.01 par value) ........      27,994,379 
  NET ASSET VALUE PER SHARE ......................................          $15.10 
                                                                   ===============
CLASS C SHARES: 
Net Assets........................................................         $20,067 
Shares Outstanding (unlimited authorized, $.01 par value) ........           1,329 
  NET ASSET VALUE PER SHARE ......................................          $15.10 
                                                                   ===============
CLASS D SHARES: 
Net Assets........................................................         $10,069 
Shares Outstanding (unlimited authorized, $.01 par value) ........             667 
  NET ASSET VALUE PER SHARE ......................................          $15.10 
                                                                   ===============
</TABLE>

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL STATEMENTS, continued 

STATEMENT OF OPERATIONS 
For the year ended July 31, 1997* 

<TABLE>
<CAPTION>
<S>                                                <C>
NET INVESTMENT INCOME: 
INCOME 
Interest .........................................    $   384,111 
Dividends (net of $5,458 foreign withholding 
 tax).............................................        361,779 
                                                   --------------
  TOTAL INCOME....................................        745,890 
                                                   --------------
EXPENSES 
Plan of distribution fee (Class B shares) ........      4,492,291 
Investment management fee.........................      4,491,688 
Transfer agent fees and expenses..................        730,898 
Registration fees.................................        145,533 
Shareholder reports and notices...................         77,955 
Professional fees ................................         62,407 
Custodian fees....................................         48,301 
Organizational expenses ..........................         32,222 
Trustees' fees and expenses.......................         20,771 
Other.............................................          9,487 
                                                   --------------
  TOTAL EXPENSES..................................     10,111,553 
                                                   --------------
  NET INVESTMENT LOSS.............................     (9,365,663) 
                                                   --------------
NET REALIZED AND UNREALIZED GAIN: 
Net realized gain ................................     14,671,544 
Net change in unrealized appreciation ............     23,334,942 
                                                   --------------
  NET GAIN .......................................     38,006,486 
                                                   --------------
NET INCREASE .....................................    $28,640,823 
                                                   ==============
</TABLE>

- ------------ 

*     Class A, Class C and Class D shares were issued July 28, 1997. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL STATEMENTS, continued 

STATEMENT OF CHANGES IN NET ASSETS 

<TABLE>
<CAPTION>
                                                                   FOR THE YEAR     FOR THE YEAR 
                                                                       ENDED            ENDED 
                                                                  JULY 31, 1997*    JULY 31, 1996 
  --------------------------------------------------------------    ------------   ------------- 
<S>                                                               <C>            <C>
INCREASE (DECREASE) IN NET ASSETS: 
OPERATIONS: 
Net investment loss..............................................  $ (9,365,663)     $ (7,836,792) 
Net realized gain ...............................................    14,671,544        38,104,756 
Net change in unrealized appreciation ...........................    23,334,942        16,813,336 
                                                                  -------------- ----------------
  NET INCREASE ..................................................    28,640,823        47,081,300 
DISTRIBUTIONS TO SHAREHOLDERS FROM NET 
 REALIZED GAIN 
  Class B shares.................................................   (28,286,327)      (22,643,391) 
Net increase (decrease) from transactions in shares of 
 beneficial interest.............................................   (20,523,010)      144,702,568 
                                                                  -------------- ----------------
  TOTAL INCREASE (DECREASE)......................................   (20,168,514)      169,140,477 
NET ASSETS: 
Beginning of period..............................................   442,875,578       273,735,101 
                                                                  -------------- ----------------
  END OF PERIOD 
  (Including accumulated net investment losses of $32,076 and 
  $28,348, respectively).........................................  $422,707,064      $442,875,578 
                                                                  ============== ================
</TABLE>

- ------------ 

*     Class A, Class C and Class D shares were issued July 28, 1997. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
NOTES TO FINANCIAL STATEMENTS July 31, 1997 

1. ORGANIZATION AND ACCOUNTING POLICIES 

Dean Witter Health Sciences Trust (the "Fund") is registered under the 
Investment Company Act of 1940, as amended (the "Act"), as a non-diversified, 
open-end management investment company. The Fund's investment objective is 
capital appreciation. The Fund seeks to achieve its objective by investing in 
securities of companies in the health sciences industry throughout the world. 
The Fund was organized as a Massachusetts business trust on May 26, 1992 and 
commenced operations on October 30, 1992. On July 28, 1997, the Fund 
commenced offering three additional classes of shares, with the then current 
shares designated as Class B shares. 

The Fund offers Class A shares, Class B shares, Class C shares and Class D 
shares. The four classes are substantially the same except that most Class A 
shares are subject to a sales charge imposed at the time of purchase, some 
Class A shares, and most Class B shares and Class C shares are subject to a 
contingent deferred sales charge imposed on shares redeemed within one year, 
six years and one year, respectively. Class D shares are not subject to a 
sales charge. Additionally, Class A shares, Class B shares and Class C shares 
incur distribution expenses. 

The preparation of financial statements in accordance with generally accepted 
accounting principles requires management to make estimates and assumptions 
that affect the reported amounts and disclosures. Actual results could differ 
from those estimates. 

The following is a summary of significant accounting policies: 

A. VALUATION OF INVESTMENTS -- (1) an equity security listed or traded on the 
New York or American or other domestic or foreign stock exchange is valued at 
its latest sale price on that exchange prior to the time when assets are 
valued; if there were no sales that day, the security is valued at the latest 
bid price (in cases where a security is traded on more than one exchange, the 
security is valued on the exchange designated as the primary market pursuant 
to procedures adopted by the Trustees); (2) all other portfolio securities 
for which over-the-counter market quotations are readily available are valued 
at the latest available bid price prior to the time of valuation; (3) when 
market quotations are not readily available, including circumstances under 
which it is determined by Dean Witter InterCapital Inc. (the "Investment 
Manager") that sale or bid prices are not reflective of a security's market 
value, portfolio securities are valued at their fair value as determined in 
good faith under procedures established by and under the general supervision 
of the Trustees (valuation of debt securities for which market quotations are 
not readily available may be based upon current market prices of securities 
which are comparable in coupon, rating and maturity or an appropriate matrix 
utilizing similar factors); (4) short-term debt securities having a maturity 
date of more than sixty days at time of purchase are valued on a 
mark-to-market basis 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
NOTES TO FINANCIAL STATEMENTS July 31, 1997, continued 

until sixty days prior to maturity and thereafter at amortized cost based on 
their value on the 61st day. Short-term debt securities having a maturity 
date of sixty days or less at the time of purchase are valued at amortized 
cost; and (5) the market value of foreign denominated portfolio securities is 
translated at the exchange rate prevailing at the end of the period. 

B. ACCOUNTING FOR INVESTMENTS -- Security transactions are accounted for on 
the trade date (date the order to buy or sell is executed). Realized gains 
and losses on security transactions are determined by the identified cost 
method. Dividend income and other distributions are recorded on the 
ex-dividend date. Discounts are accreted over the life of the respective 
securities. Interest income is accrued daily. 

Investment income, expenses (other than distribution fees), and realized and 
unrealized gains and losses are allocated to each class of shares based upon 
the relative net asset value on the date the income is earned or expenses and 
realized and unrealized gains and losses are incurred. Distribution fees are 
charged directly to the respective class. 

C. FEDERAL INCOME TAX STATUS -- It is the Fund's policy to comply with the 
requirements of the Internal Revenue Code applicable to regulated investment 
companies and to distribute all of its taxable income to its shareholders. 
Accordingly, no federal income tax provision is required. 

D. DIVIDENDS AND DISTRIBUTIONS TO SHAREHOLDERS -- The Fund records dividends 
and distributions to its shareholders on the ex-dividend date. The amount of 
dividends and distributions from net investment income and net realized 
capital gains are determined in accordance with federal income tax 
regulations which may differ from generally accepted accounting principles. 
These "book/tax" differences are either considered temporary or permanent in 
nature. To the extent these differences are permanent in nature, such amounts 
are reclassified within the capital accounts based on their federal tax-basis 
treatment; temporary differences do not require reclassification. Dividends 
and distributions which exceed net investment income and net realized capital 
gains for financial reporting purposes but not for tax purposes are reported 
as dividends in excess of net investment income or distributions in excess of 
net realized capital gains. To the extent they exceed net investment income 
and net realized capital gains for tax purposes, they are reported as 
distributions of paid-in-capital. 

E. ORGANIZATIONAL EXPENSES -- The Investment Manager paid the organizational 
expenses of the Fund in the amount of approximately $162,000 which have been 
reimbursed for the full amount thereof. Such expenses have been deferred and 
are being amortized on the straight-line method over a period not to exceed 
five years from the commencement of operations. 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
NOTES TO FINANCIAL STATEMENTS July 31, 1997, continued 

2. INVESTMENT MANAGEMENT AGREEMENT 

Pursuant to an Investment Management Agreement, the Fund pays the Investment 
Manager a management fee, accrued daily and payable monthly, by applying the 
following annual rates to the net assets of the Fund determined at the close 
of each business day: 1.0% to the portion of daily net assets not exceeding 
$500 million and 0.95% to the portion of daily net assets exceeding $500 
million. 

Under the terms of the Agreement, in addition to managing the Fund's 
investments, the Investment Manager maintains certain of the Fund's books and 
records and furnishes, at its own expense, office space, facilities, 
equipment, clerical, bookkeeping and certain legal services and pays the 
salaries of all personnel, including officers of the Fund who are employees 
of the Investment Manager. The Investment Manager also bears the cost of 
telephone services, heat, light, power and other utilities provided to the 
Fund. 

3. PLAN OF DISTRIBUTION 

Shares of the Fund are distributed by Dean Witter Distributors Inc. (the 
"Distributor"), an affiliate of the Investment Manager. The Fund has adopted 
a Plan of Distribution (the "Plan") pursuant to Rule 12b-1 under the Act. The 
plan provides that the Fund will pay the Distributor a fee which is accrued 
daily and paid monthly at the following annual rates: (i) Class A -0.25% of 
the average daily net assets of Class A; (ii) Class B -1.0% of the lesser of: 
(a) the average daily aggregate gross sales of the Class B shares since the 
inception of the Fund (not including reinvestment of dividend or capital gain 
distributions) less the average daily aggregate net asset value of the Class 
B shares redeemed since the Fund's inception upon which a contingent deferred 
sales charge has been imposed or waived; or (b) the average daily net assets 
of Class B; and (iii) Class C -1.0% of the average daily net assets of Class 
C. In the case of Class A shares, amounts paid under the Plan are paid to the 
Distributor for services provided. In the case of Class B and Class C shares, 
amounts paid under the Plan are paid to the Distributor for services provided 
and the expenses borne by it and others in the distribution of the shares of 
these Classes, including the payment of commissions for sales of these 
Classes and incentive compensation to, and expenses of, the account 
executives of Dean Witter Reynolds Inc. ("DWR"), an affiliate of the 
Investment Manager and Distributor, and others who engage in or support 
distribution of the shares or who service shareholder accounts, including 
overhead and telephone expenses; printing and distribution of prospectuses 
and reports used in connection with the offering of these shares to other 
than current shareholders; and preparation, printing and distribution of 
sales literature and advertising materials. In addition, the Distributor may 
utilize fees paid pursuant to the Plan, in the case of Class B shares, to 
compensate DWR 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
NOTES TO FINANCIAL STATEMENTS July 31, 1997, continued 

and other selected broker-dealers for their opportunity costs in advancing 
such amounts, which compensation would be in the form of a carrying charge on 
any unreimbursed expenses. 

In the case of Class B shares, provided that the Plan continues in effect, 
any cumulative expenses incurred by the Distributor but not yet recovered may 
be recovered through the payment of future distribution fees from the Fund 
pursuant to the Plan and contingent deferred sales charges paid by investors 
upon redemption of Class B shares. Although there is no legal obligation for 
the Fund to pay expenses incurred in excess of payments made to the 
Distributor under the Plan and the proceeds of contingent deferred sales 
charges paid by investors upon redemption of shares, if for any reason the 
Plan is terminated, the Trustees will consider at that time the manner in 
which to treat such expenses. The Distributor has advised the Fund that such 
excess amounts, including carrying charges, totaled $16,338,844 at July 31, 
1997. 

In the case of Class A shares and Class C shares, expenses incurred pursuant 
to the Plan in any calendar year in excess of 0.25% or 1.0% of the average 
daily net assets of Class A or Class C, respectively, will not be reimbursed 
by the Fund through payments in any subsequent year, except that expenses 
representing a gross sales credit to account executives may be reimbursed in 
the subsequent calendar year. For the period ended July 31, 1997, the 
distribution fee was accrued for Class A shares and Class C shares at the 
annual rate of 0.25% and 1.0%, respectively. 

The Distributor has informed the Fund that for the year ended July 31, 1997, 
it received contingent deferred sales charges from certain redemptions of the 
Fund's Class B shares of approximately $1,142,000. The shareholders pay such 
charges which are not an expense of the Fund. 

4. SECURITY TRANSACTIONS AND TRANSACTIONS WITH AFFILIATES 

The cost of purchases and proceeds from sales of portfolio securities, 
excluding short-term investments, for the year ended July 31, 1997 aggregated 
$369,644,528 and $418,622,260, respectively. 

For the year ended July 31, 1997, the Fund incurred brokerage commissions of 
$10,330 with DWR for portfolio transactions executed on behalf of the Fund. 

Dean Witter Trust Company, an affiliate of the Investment Manager and 
Distributor, is the Fund's transfer agent. At July 31, 1997, the Fund had 
transfer agent fees and expenses payable of approximately $2,800. 

The Fund has an unfunded noncontributory defined benefit pension plan 
covering all independent Trustees of the Fund who will have served as 
independent Trustees for at least five years at the time of retirement. 
Benefits under this plan are based on years of service and compensation 
during the last five years of service. Aggregate pension costs for the year 
ended July 31, 1997 included in Trustees' fees and 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
NOTES TO FINANCIAL STATEMENTS July 31, 1997, continued 

expenses in the Statement of Operations amounted to $5,225. At July 31, 1997, 
the Fund had an accrued pension liability of $32,076 which is included in 
accrued expenses in the Statement of Assets and Liabilities. 

5. SHARES OF BENEFICIAL INTEREST 

Transactions in shares of beneficial interest were as follows: 

<TABLE>
<CAPTION>
                                                       FOR THE YEAR                    FOR THE YEAR 
                                                           ENDED                           ENDED 
                                                       JULY 31, 1997                   JULY 31, 1996 
                                              ------------------------------- ------------------------------- 
                                                  SHARES          AMOUNT          SHARES          AMOUNT 
                                              -------------- ---------------  -------------- --------------- 
<S>                                           <C>            <C>              <C>            <C>
CLASS A SHARES* 
Sold ........................................           667    $      10,018         --              -- 
                                              -------------- ---------------  -------------- --------------- 
CLASS B SHARES 
Sold.........................................    12,042,815      183,250,429     26,005,478    $ 429,545,190 
Reinvestment of dividends and distributions       1,860,102       26,655,267      1,434,910       21,121,878 
Redeemed.....................................   (15,501,740)    (230,468,760)   (19,102,244)    (305,964,500) 
                                              -------------  ---------------  -------------  --------------- 
Net increase (decrease) -Class B.............    (1,598,823)     (20,563,064)     8,338,144      144,702,568 
                                              -------------  ---------------  -------------  --------------- 
CLASS C SHARES* 
Sold.........................................         1,329           20,018         --              -- 
                                              -------------  ---------------  -------------  --------------- 
CLASS D SHARES* 
Sold.........................................           667           10,018         --              -- 
                                              -------------  ---------------  -------------  --------------- 
Net increase (decrease) in Fund..............    (1,596,160)   $ (20,523,010)     8,338,144    $ 144,702,568 
                                              =============  ===============  =============  =============== 
</TABLE>

- ------------ 
* For the period July 28, 1997 (issue date) through July 31, 1997. 

6. FEDERAL INCOME TAX STATUS 

As of July 31, 1997, the Fund had temporary book/tax differences primarily 
attributable to capital loss deferrals on wash sales and permanent book/tax 
differences attributable to a net operating loss. To reflect 
reclassifications arising from the permanent differences, paid-in-capital was 
charged and accumulated net investment loss was credited $9,361,935. 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL HIGHLIGHTS 

Selected ratios and per share data for a share of beneficial interest 
outstanding throughout each period: 

<TABLE>
<CAPTION>
                                                     FOR THE YEAR ENDED JULY 31, 
                                            --------------------------------------------- 
                                                                                            FOR THE PERIOD 
                                                                                          OCTOBER 30, 1992* 
                                                                                               THROUGH 
                                              1997**       1996       1995        1994      JULY 31, 1993 
- ------------------------------------------  ---------- ----------  ---------- ----------  ----------------- 
<S>                                         <C>        <C>         <C>        <C>         <C>
CLASS B SHARES 
PER SHARE OPERATING PERFORMANCE: 
Net asset value, beginning of period ......   $14.97      $12.88     $ 9.32      $ 9.22         $10.00 
                                            ---------  ---------   --------   ---------   ------------      
Net investment loss........................    (0.31)      (0.26)     (0.24)      (0.22)         (0.08) 
Net realized and unrealized gain (loss) ...     1.39        3.44       3.80        0.32          (0.70) 
                                            ---------  ---------   --------   ---------   ------------
Total from investment operations...........     1.08        3.18       3.56        0.10          (0.78) 
                                            ---------  ---------   --------   ---------   ------------      
Less distributions from net realized gain      (0.95)      (1.09)      --          --             -- 
                                            ---------  ---------   --------   ---------   ------------      
Net asset value, end of period ............   $15.10      $14.97     $12.88      $ 9.32         $ 9.22 
                                            =========  =========   ========   =========   ============      
TOTAL INVESTMENT RETURN+ ..................     7.55%      24.84%     38.20%       1.08%         (7.80)%(1) 
RATIOS TO AVERAGE NET ASSETS: 
Expenses...................................     2.25%       2.20%      2.30%       2.30%          2.38%(2) 
Net investment loss........................    (2.08)%     (2.03)%    (2.05)%     (2.06)%        (1.38)%(2) 
SUPPLEMENTAL DATA: 
Net assets, end of period, in thousands ... $422,667   $ 442,876   $273,735    $228,573       $231,646 
Portfolio turnover rate....................       85%         63%       145%        106%            55%(1) 
Average commission rate paid............... $ 0.0566    $ 0.0562         --          --             -- 

</TABLE>

- ------------ 
  *    Commencement of operations. 
 **    Class B shares were issued July 28, 1997. All shares of the Fund held 
       prior to that date have been designated Class B shares. 
  +    Does not reflect the deduction of sales charge. Calculated based on the 
       net asset value as of the last business day of the period. 
(1)    Not annualized. 
(2)    Annualized. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL HIGHLIGHTS, continued 

<TABLE>
<CAPTION>
                                          FOR THE PERIOD 
                                          JULY 28, 1997* 
                                              THROUGH 
                                           JULY 31, 1997 
- ----------------------------------------  -------------- 
<S>                                       <C>
CLASS A SHARES 
PER SHARE OPERATING PERFORMANCE: 
Net asset value, beginning of period ....     $ 15.03 
Net realized and unrealized gain  .......        0.07 
                                          -----------    
Net asset value, end of period ..........     $ 15.10 
                                          ===========    
TOTAL INVESTMENT RETURN+  ...............        0.47%(1) 
RATIOS TO AVERAGE NET ASSETS: 
Expenses ................................        1.57%(2) 
Net investment loss .....................       (0.55)%(2) 
SUPPLEMENTAL DATA: 
Net assets, end of period, in thousands       $    10 
Portfolio turnover rate .................          85% 
Average commission rate paid ............     $0.0566 

CLASS C SHARES 
PER SHARE OPERATING PERFORMANCE: 
Net asset value, beginning of period ....     $ 15.03 
Net realized and unrealized gain  .......        0.07 
                                          -----------    
Net asset value, end of period ..........     $ 15.10 
                                          ===========    
TOTAL INVESTMENT RETURN+  ...............        0.47%(1) 
RATIOS TO AVERAGE NET ASSETS: 
Expenses ................................        2.31%(2) 
Net investment loss .....................       (1.28)%(2) 
SUPPLEMENTAL DATA: 
Net assets, end of period, in thousands       $    20 
Portfolio turnover rate .................          85% 
Average commission rate paid ............     $0.0566 
</TABLE>

- ------------ 
*      The date shares were first issued. 
+      Does not reflect the deduction of sales charge. Calculated based on the 
       net asset value as of the last business day of the period. 
(1)    Not annualized. 
(2)    Annualized. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
FINANCIAL HIGHLIGHTS, continued 

<TABLE>
<CAPTION>
                                          FOR THE PERIOD 
                                          JULY 28, 1997* 
                                              THROUGH 
                                           JULY 31, 1997 
- ----------------------------------------  -------------- 
<S>                                       <C>
CLASS D SHARES 
PER SHARE OPERATING PERFORMANCE: 
Net asset value, beginning of period ....     $ 15.03 
Net realized and unrealized gain  .......        0.07 
                                          -----------    
Net asset value, end of period ..........     $ 15.10 
                                          ===========    
TOTAL INVESTMENT RETURN+ ................        0.47%(1) 
RATIOS TO AVERAGE NET ASSETS: 
Expenses ................................        1.31%(2) 
Net investment loss .....................       (0.29)%(2) 
SUPPLEMENTAL DATA: 
Net assets, end of period, in thousands       $    10 
Portfolio turnover rate .................          85% 
Average commission rate paid ............     $0.0566 
</TABLE>

- ------------ 
  *    The date shares were first issued. 
  +    Calculated based on the net asset value as of the last business day of 
       the period. 
(1)    Not annualized. 
(2)    Annualized. 

                      SEE NOTES TO FINANCIAL STATEMENTS 

<PAGE>
DEAN WITTER HEALTH SCIENCES TRUST 
REPORT OF INDEPENDENT ACCOUNTANTS 

TO THE SHAREHOLDERS AND TRUSTEES 
OF DEAN WITTER HEALTH SCIENCES TRUST 

In our opinion, the accompanying statement of assets and liabilities, 
including the portfolio of investments, and the related statements of 
operations and of changes in net assets and the financial highlights present 
fairly, in all material respects, the financial position of Dean Witter 
Health Sciences Trust (the "Fund") at July 31, 1997, the results of its 
operations for the year then ended, the changes in its net assets for each of 
the two years in the period then ended and the financial highlights for each 
of the periods presented, in conformity with generally accepted accounting 
principles. These financial statements and financial highlights (hereafter 
referred to as "financial statements") are the responsibility of the Fund's 
management; our responsibility is to express an opinion on these financial 
statements based on our audits. We conducted our audits of these financial 
statements in accordance with generally accepted auditing standards which 
require that we plan and perform the audit to obtain reasonable assurance 
about whether the financial statements are free of material misstatement. An 
audit includes examining, on a test basis, evidence supporting the amounts 
and disclosures in the financial statements, assessing the accounting 
principles used and significant estimates made by management, and evaluating 
the overall financial statement presentation. We believe that our audits, 
which included confirmation of securities at July 31, 1997 by correspondence 
with the custodian and brokers and the application of alternative auditing 
procedures where confirmations from brokers were not received, provide a 
reasonable basis for the opinion expressed above. 

PRICE WATERHOUSE LLP 
1177 Avenue of the Americas 
New York, New York 10036 
September 12, 1997 

                     1997 FEDERAL TAX NOTICE (unaudited) 

 During the year ended July 31, 1997, the Fund paid to its shareholders $0.95 
 per share from long-term capital gains. 

<PAGE>
TRUSTEES 
Michael Bozic
Charles A. Fiumefreddo 
Edwin J. Garn 
John R. Haire 
Wayne E. Hedien 
Dr. Manuel H. Johnson 
Michael E. Nugent 
Philip J. Purcell 
John L. Schroeder 

OFFICERS 
Charles A. Fiumefreddo 
Chairman and Chief Executive Officer 
Barry Fink 
Vice President, Secretary and General Counsel 
Ronald J. Worobel 
Vice President 
Thomas F. Caloia 
Treasurer 

TRANSFER AGENT 
Dean Witter Trust FSB 
Harborside Financial Center -- Plaza Two 
Jersey City, New Jersey 07311 

INDEPENDENT ACCOUNTANTS 
Price Waterhouse LLP 
1177 Avenue of the Americas 
New York, New York 10036 

INVESTMENT MANAGER 
Dean Witter InterCapital Inc. 
Two World Trade Center 
New York, New York 10048 

ADVISER 
TCW Funds Management, Inc. 

This report is submitted for the general information of shareholders of the 
Fund. For more detailed information about the Fund, its offices and trustees, 
fees, expenses and other pertinent information, please see the prospectus of 
the Fund. 

This report is not authorized for distribution to prospective investors in 
the Fund unless preceded or accompanied by an effective prospectus. 

Dean Witter 
Health Sciences 
Trust 

ANNUAL REPORT 
JULY 31, 1997 








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