ACCUMED INTERNATIONAL INC
S-8, 1996-08-30
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1
   

   As filed with the Securities and Exchange Commission on August 30, 1996

                                                Registration No. 333-
      _________________________________________________________________

                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549
                                ----------------
                                    FORM S-8
                             REGISTRATION STATEMENT
                                     Under
                           THE SECURITIES ACT OF 1933
                                ----------------
                           ACCUMED INTERNATIONAL,INC.
             (Exact name of registrant as specified in its charter)

             Delaware                                     36-4054899    
  (State or other jurisdiction of                     (I.R.S. Employer
   incorporation or organization)                     Identification No.)

                       900 N. Franklin Street, Suite 401
                          Chicago, Illinois  60610            
              (Address of Principal Executive Offices) (zip code)

                  Amended and Restated 1990 Stock Option Plan,
                  Amended and Restated 1992 Stock Option Plan
                                      and
                      1995 Stock Option Plan, as amended     
                           (Full Title of the Plans)

                               Peter P. Gombrich
                            Chief Executive Officer
                          AccuMed International, Inc.
                       900 N. Franklin Street, Suite 401
                              Chicago, Illinois  60610       
                    (Name and address of agent for service)

                                  312-642-9200                              
         (Telephone number, including area code, of agent for service)

                                With a copy to:
                             GILLES S. ATTIA, ESQ.
                                 Graham & James
                          400 Capitol Mall, Suite 2400
                         Sacramento, California  95814
                                 (916) 558-6700

                        CALCULATION OF REGISTRATION FEE

<TABLE>
<CAPTION>
====================================================================================================================================
                                                        Proposed               Proposed
        Title of                                        maximum                 maximum
       securities                Amount                 offering               aggregate               Amount of
         to be                   to be                 price per               offering              registration
       registered              registered               share(1)               price(1)                   fee
====================================================================================================================================
     <S>                       <C>                       <C>                  <C>                       <C>
     Common Stock,             507,895(2)                $6.13                $3,113,396                $1,074
      par value $0.01
====================================================================================================================================
</TABLE>

         (1)     Estimated solely for the purpose of calculating the
                 registration fee pursuant to Rule 457(h) and Rule 457(c) under
                 the Securities Act of 1933 based on average of the high and
                 low prices of a share of common stock of the Company reported
                 for trading on the Nasdaq SmallCap Market on August 27, 1996.

         (2)     500,000 shares of common stock are issuable upon exercise of
                 options authorized to be granted pursuant to an amendment to
                 the 1995 Stock Option Plan adopted subsequent to the original
                 filing of the Registration Statement.  An additional 7,895
                 shares available under the Company's Amended and Restated 1992
                 Stock Option Plan are also registered hereby; such shares were
                 inadvertently omitted from the original Registration
                 Statement.
    





<PAGE>   2
                                    PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
   

         The Registrant hereby incorporates by reference herein the contents of
its Registration Statement on Form S-8 (Reg. No. 333-4320) filed with the
Securities and Exchange Commission (the "Commission") on May 1, 1996.

    
ITEM 8.          EXHIBITS.

                 The following exhibits are filed with this Registration
                 Statement.

<TABLE>
<CAPTION>
                 Number   Description of Exhibit
                 ------   ----------------------
                 <S>      <C>
                 4.1      Amended and Restated 1990 Stock Option Plan
                          (incorporated by reference to the Registrant's
                          Registration Statement on Form S-1 (Reg. No.
                          33-48302) filed with the Commission on June 3, 1992).

                 4.2      Amended and Restated 1992 Stock Option Plan
                          (incorporated by reference to the Registrant's
                          Pre-Effective Amendment No. 1 on Form SB-2 filed
                          with the Commission on November 8, 1993).

                 4.3      1995 Stock Option Plan (incorporated by reference
                          to the Registrant's Transition Report on Form
                          10-KSB for the transition period ended December 31,
                          1995 (the "Transition Report")).

   
                 4.4      Amendment, effective July 12, 1996, to the
                          Registrant's 1995 Stock Option Plan, increasing
                          the number of shares available.

                 4.5      Form of 1992 Plan Incentive Stock Option Agreement
                          (previously filed with this Registration Statement
                          on Form S-8 on May 1, 1996).

                 4.6      Form of 1992 Plan Nonstatutory Stock Option
                          Agreement (previously filed with this Registration
                          Statement on Form S-8 on May 1, 1996).

                 4.7      Form of 1990 Plan Incentive Stock Option Agreement
                          (previously filed with this Registration Statement
                          on Form S-8 on May 1, 1996).

                 4.8      Form of 1990 Plan Nonqualified Stock Option
                          Agreement (previously filed with this Registration
                          Statement on Form S-8 on May 1, 1996).
</TABLE>
    





<PAGE>   3
<TABLE>
<S>              <C>      <C>
                 4.9      Form of 1995 Plan Incentive Stock Option Agreement
                          (incorporated by reference to the Transition
                          Report).

                 4.10     Form of 1995 Plan Non-Qualified Stock Option
                          Agreement (incorporated by reference to the
                          Transition Report).

                 4.11     Form of Non-qualified Stock Option Agreement
                          governing options granted to former employees of
                          AccuMed, Inc. under the 1995 Plan pursuant to the
                          Agreement and Plan of Reorganization dated as of
                          April 21, 1995, as amended (incorporated by
                          reference to the Transition Report).

                 5.1      Opinion of Graham & James LLP regarding legality
                          of the additional shares of Common Stock available
                          under the 1995 Stock Option Plan, as amended.

                 23.1     Consent of Graham & James LLP (incorporated by
                          reference to Exhibit 5.1 hereof).

                 23.2     Consent of Coopers & Lybrand LLP.

   
                 23.3     Consent to Coopers & Lybrand.
    
                 23.4     Consent of KPMG Peat Marwick LLP.
</TABLE>





                                      II-2
<PAGE>   4
                                   SIGNATURES

   

         Pursuant to the requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this Registration
Statement on Form S-8 to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Chicago, State of Illinois, on the 30th day of
August, 1996.

    

                                  ACCUMED INTERNATIONAL, INC.

                                  By: /s/ Peter P. Gombrich
                                     ---------------------------------
                                     Peter P. Gombrich
                                     Chief Executive Officer


                               POWER OF ATTORNEY

   
                 KNOW ALL PERSONS BY THESE PRESENTS, that each person whose
signature appears below constitutes and appoints Peter P. Gombrich as
attorney-in-fact for the undersigned, with the power of substitution, for the
undersigned in any and all capacities, to sign any and all amendments to this
Registration Statement (including post-effective amendments) and any new
registration statement filed under Rule 462(b) under the Securities Act of
1933) and any post-effective amendment thereto, and to file the same, with all
exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, hereby ratifying and confirming that said
attorney-in-fact or his substitute or substitutes may lawfully do or cause to
be done by virtue hereof.

                 In accordance with the requirements of the Securities Act of
1933, this Registration Statement on Form S-8 has been signed by the following
persons in the capacities and on the dates stated.

<TABLE>
<CAPTION>
Signature                                          Title                                              Date
- ---------                                          -----                                              ----
<S>                                        <C>                                                <C>
 /s/ Peter P. Gombrich                     Chairman of the Board, Chief                       August 30, 1996
- -------------------------------------      Executive Officer and President
(Peter P. Gombrich)                        (Principal Executive Officer)
                                           

 /s/ Mark L. Santor                        Chief Financial Officer (Principal                 August 30, 1996
- -------------------------------------      Financial and Accounting Officer)
(Mark L. Santor)                           

 /s/ John H. Abeles                                Director                                   August 29, 1996
- -------------------------------------                                                                             
(John H. Abeles)

                                                   Director                                   _________, 1996
- -------------------------------------                                                                             
(Harold S. Blue)

                                                   Director                                   _________, 1996
- -------------------------------------                                                                             
(Jack H. Halperin)

                                                   Director                                   _________, 1996
- -------------------------------------                                                                             
(Paul F. Lavallee)

 /s/ Joseph Plandowski                             Director                                   August 29, 1996
- -------------------------------------                                                                             
(Joseph W. Plandowski)

 /s/ Leonard Schiller                              Director                                   August 29, 1996
- -------------------------------------                                                                             
(Leonard M. Schiller)
</TABLE>

    





                                      II-3
<PAGE>   5
                               INDEX TO EXHIBITS

<TABLE>
<CAPTION>
Exhibit Number   Description of Exhibit
- --------------   ----------------------
<S>              <C>
4.1              Amended and Restated 1990 Stock Option Plan
                 (incorporated by reference to the Registrant's
                 Registration Statement on Form S-1 (Reg. No.
                 33-48302) filed with the Commission on June 3, 1992).

4.2              Amended and Restated 1992 Stock Option Plan
                 (incorporated by reference to the Registrant's
                 Pre-Effective Amendment No. 1 on Form SB-2 filed
                 with the Commission on November 8, 1993).

4.3              1995 Stock Option Plan (incorporated by reference
                 to the Registrant's Transition Report on Form
                 10-KSB for the transition period ended December 31,
                 1995 (the "Transition Report")).

   
4.4              Amendment, effective July 12, 1996, to the Registrant's
                 1995 Stock Option Plan, increasing the number of shares
                 available.

4.5              Form of 1992 Plan Incentive Stock Option Agreement
                 (previously filed with this Registration Statement on Form
                 S-8 on May 1, 1996).

4.6              Form of 1992 Plan Nonstatutory Stock Option Agreement
                 (previously filed with this Registration Statement on Form
                 S-8 on May 1, 1996).

4.7              Form of 1990 Plan Incentive Stock Option Agreement
                 (previously filed with this Registration Statement on Form
                 S-8 on May 1, 1996).

4.8              Form of 1990 Plan Nonqualified Stock Option Agreement
                 (previously filed with this Registration Statement on Form
                 S-8 on May 1, 1996).

    
4.9              Form of 1995 Plan Incentive Stock Option Agreement
                 (incorporated by reference to the Transition Report).

4.10             Form of 1995 Plan Non-Qualified Stock Option Agreement
                 (incorporated by reference to the Transition Report).

4.11             Form of Non-qualified Stock Option Agreement governing
                 options granted to former employees of AccuMed, Inc. under
                 the 1995 Plan pursuant to the Agreement and Plan of
                 Reorganization dated as of April 21, 1995, as amended
                 (incorporated by reference to the Transition Report).

5.1              Opinion of Graham & James LLP regarding
                 legality of the shares of Common Stock.

23.1             Consent of Graham & James LLP,
                 (incorporated by reference to Exhibit 5.1
                 hereof.)

23.2             Consent of Coopers & Lybrand LLP.

   

23.3             Consent to Coopers & Lybrand.

    

23.4             Consent of KPMG Peat Marwick LLP.
</TABLE>

<PAGE>   1
                                                                     EXHIBIT 4.4

                          ACCUMED INTERNATIONAL, INC.

                            SECRETARY'S CERTIFICATE



         I, Mark L. Santor, Secretary of AccuMed International, Inc., a
Delaware corporation (the "Corporation"), hereby certify as follows:

         1.      Attached hereto as Exhibit A is a true, correct and complete
copy of the resolutions of the Board of Directors of the Corporation dated July
12, 1996 approving the increase in authorized number of shares issuable upon
exercise of options authorized to be granted under the Corporation's 1995 Stock
Option Plan.  Such resolutions have not been modified, repealed or rescinded
and remain in full force and effect as of the date of this Certificate.

                 IN WITNESS WHEREOF, I have executed this Certificate as
Officer of the Corporation this 15th day of August, 1996.


                                  /s/ Mark L. Santor       
                                 --------------------------- 
                                 Mark L. Santor
                                 Secretary
<PAGE>   2
                    AMENDMENT TO ACCUMED INTERNATIONAL, INC.
                             1995 STOCK OPTION PLAN


         AMENDMENT (this "Amendment") to the AccuMed International, Inc.
(formerly "Alamar Biosciences, Inc., the "Company") 1995 Stock Option Plan (the
"Plan") dated July 12, 1996.

         WHEREAS, the Plan currently provides for the grant of options to
purchase up to an aggregate of 1,500,000 shares of the Company's common stock,
par value of $.01 per share (the "Common Stock");

         WHEREAS, on July 12, 1996 the Board of Directors adopted resolutions
amending the Plan, subject to stockholder approval within 12 months thereafter,
to increase the number of shares available under the Plan and provide for the
grant of options to purchase an aggregate of 2,000,000 shares of the Common
Stock (a copy of such resolutions, certified by the Secretary of the Company
are attached hereto as Exhibit A);

         NOW, THEREFORE, in accordance with Section 11 of the Plan, the Plan is
hereby amended as follows:

         1.      Section 4 of the Plan is hereby deleted in its entirety and
                 the following is inserted in lieu thereof:

                 Section 4.  Shares Available.  Subject to adjustment as
                 provided in Section 16 of this Plan, 2,000,000 shares of the
                 common stock, par value of $.01 per share, of the Company (the
                 "Common Stock"), shall be available for grants of options
                 under this Plan.  To the extent an outstanding option expires
                 or terminates unexercised or is canceled or forfeited, the
                 shares of Common Stock subject to the expired, unexercised,
                 canceled or forfeited portion of such option shall again be
                 available for grants of options under this Plan.  Shares of
                 Common Stock to be delivered under this Plan shall be
                 authorized and unissued shares of Common Stock, or authorized
                 and issued shares of Common Stock reacquired and held as
                 treasury shares or otherwise or a combination thereof.

         All other provisions of the Plan shall remain in full force and
effect.





                                       2

<PAGE>   1
                                                                     EXHIBIT 5.1
                                  [LETTERHEAD]



August 30, 1996

AccuMed International, Inc.
900 N. Franklin Street, Ste. 401
Chicago, IL 60610


Gentlemen:

You have requested our opinion as counsel for AccuMed International, Inc., a
Delaware corporation (the "Company"), in connection with the registration under
the Securities Act of 1933, as amended (the "Securities Act"), and the Rules
and Regulations promulgated thereunder, of an aggregate of 507,895 shares (the
"Shares") of the Company's common stock, par value $0.01 per share (the "Common
Stock"), issuable upon exercise of stock options granted or to be granted in
connection with the Company's Amended and Restated 1992 Stock Option Plan (the
"1992 Plan") and the 1995 Stock Option Plan, as amended (the "1995 Plan" and
together with the 1992 Plan, the "Option Plans").

This opinion is rendered pursuant to Item 601(b)(5)(i) of Regulation S-B
promulgated under the Securities Act.

For purposes of this opinion, we have examined the Registration Statement on
Form S-8 (Reg. No. 333-04320) filed with the Commission on May 1, 1996, the
exhibits thereto, and the Registration Statement on Form S-8 (the "Registration
Statement") to be filed with the Commission on or about August 30, 1996.  We
have also been furnished with and have examined originals or copies, certified
or otherwise identified to our satisfaction, of all such records of the Company,
agreements and other instruments, certificates of officers and representatives
of the Company, certificates of public officials and other documents as we have
deemed it necessary as a basis for the opinions hereafter expressed.  As to
questions of fact material to such opinions, we have, where relevant facts were
not independently established, relied upon certifications by principal officers
of the Company.  We have made such further legal and factual examination and
investigation as we deem necessary for purposes of rendering the following
opinions.





                                       3
<PAGE>   2
AccuMed International, Inc.
August 30, 1996
Page 2

In our examination we have assumed the genuineness of all signatures, the legal
capacity of natural persons, the correctness of facts set forth in
certificates, the authenticity of all documents submitted to us as originals,
the conformity to original documents of all documents submitted to us as
certified or photostatic copies, and the authenticity of the originals of such
copies.  We have also assumed that such documents have each been duly
authorized, properly executed and delivered by each of the parties thereto
other than the Company.

We are members of the bar of the State of California.  Our opinions below are
limited to the laws of the State of California, the General Corporation Law of
the State of Delaware and the federal securities laws of the United States.

Based on the foregoing, it is our opinion that all of the Shares, when issued
and delivered against payment in full of the respective exercise prices in
accordance with the terms of the respective Option Plans and option agreements
governing such options, will be legally and validly issued, fully paid and
nonassessable.

We consent to the filing of this opinion as an exhibit to the Post-Effective
Amendment.

Very truly yours,


/s/ Graham & James LLP
GRAHAM & JAMES LLP





                                       4

<PAGE>   1
                                                                    EXHIBIT 23.2

                         CONSENT OF INDEPENDENT ACCOUNTANTS

We consent to the incorporation by reference in this Registration Statement on
Form S-8, to be filed with the Commission on or about August 30, 1996, of our
report dated September 14, 1995, on our audit of the balance sheet of
Sensititre/Alamar, the Microbiology Division of AccuMed, Inc., as of December
31, 1994, and the net sales, cost of sales and selling expenses for the eight
months ended December 31, 1994, and the years ended April 30, 1994 and 1993; of
our report, which includes an explanatory paragraph related to substantial doubt
about the ability of AccuMed, Inc. to continue as a going concern, dated
September 29, 1995, on our audit of the balance sheet of AccuMed, Inc. as of
December 31, 1994, and for the period from February 7, 1994 (inception) through
December 31, 1994, appearing in the registration statement on Form S-4 (SEC File
No. 33-99680) of Alamar Biosciences, Inc. filed with the Securities and Exchange
Commission pursuant to the Securities Act of 1933 as incorporated by reference
in the Current Report on Form 8-K dated December 29, 1995; and of our report,
which includes an explanatory paragraph related to substantial doubt about the
ability of Alamar Biosciences, Inc. to continue as a going concern, dated
November 19, 1995, on our audits of the financial statements of Alamar
Biosciences, Inc. as of September 30, 1995 and 1994, and for the years ended
September 30, 1995, 1994 and 1993, which report is included in the Annual Report
on Form 10-KSB for the year ended September 30, 1995.


/s/ Coopers & Lybrand LLP


Sacramento, CA
August 30, 1996





                                       5

<PAGE>   1

                                                                    EXHIBIT 23.3

                       CONSENT OF INDEPENDENT ACCOUNTANTS

We consent to the incorporation by reference in this Registration Statement on
Form S-8, to be filed with the Commission on or about August 30, 1996, of our
report dated December 8, 1995, on our audit of the balance sheets of AccuMed
International Limited as of December 31, 1994, April 30, 1994 and 1993, and
related statements of operations and cashflows for the eight months ended
December 31, 1994, and the years ended April 30, 1994 and 1993, appearing in the
registration statement on Form S-4 (SEC File No. 33-99680) of Alamar
Biosciences, Inc. filed with the Securities and Exchange Commission pursuant to
the Securities Act of 1933 as incorporated by reference in the Current Report on
Form 8-K dated December 29, 1995.



/s/ Coopers & Lybrand


Croydon
United Kingdom
August 30, 1996





                                       6

<PAGE>   1
                                                                    EXHIBIT 23.4

                 REPORT AND CONSENT OF INDEPENDENT ACCOUNTANTS

Board of Directors and Stockholders
AccuMed International, Inc.:

   We consent to the incorporation by reference in this Registration Statement 
on Form S-8 of our report dated April 5, 1996, relating to the consolidated 
balance sheet of AccuMed International, Inc. and subsidiaries as of 
December 31, 1995 and the related consolidated statements of operations, 
stockholders' equity and cash flows for the three months ended December 31, 
1995, which report appears in the December 31, 1995 transition report on 
Form 10-K of AccuMed International, Inc.


/s/ KPMG Peat Marwick LLP


Chicago, Illinois
August 30, 1996





                                       7


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