METRA BIOSYSTEMS INC
8-K, 1997-05-09
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                          SECURITIES AND EXCHANGE COMMISSION

                                Washington, D.C. 20549

                                       FORM 8-K
                                           
      CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
                                      ACT OF 1934
                                           
                             DATE OF REPORT  May 2, 1997
                                           
                                           
                               ________________________
                                           
                                METRA BIOSYSTEMS, INC.
                                           
                                           
                (Exact name of registrant as specified in its charter)
                                           
                                       0-26234
                               (Commission File Number)
                                           
        California                                   33-0408436
(State or other jurisdiction of          (I.R.S. Employer Identification No.)
 incorporation or organization)


                                265 North Whisman Road
                               Mountain View, CA 94043
               (Address of principal executive offices, with zip code)


                                    (415) 903-9100
                 (Registrant's telephone number, including area code)
                                           
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Item 4. Changes in Registrant's Certifying Accountants

        (a)   Effective May 2, 1997, the Board of Directors of Metra 
Biosystems, Inc. (the "Company") engaged the accounting firm of Ernst & Young 
LLP as independent public accountants for the Registrant.  The Company's 
former independent public accountants, KPMG Peat Marwick LLP, were dismissed 
effective May 2, 1997.  The Registrant's audit committee recommended, and the 
Company's Board of Directors approved, these actions.
        
        (b)   During the two most recent fiscal years and subsequent interim 
periods prior to May 2, 1997, there were no disagreements with KPMG Peat 
Marwick LLP on any matter of accounting principles or practices, financial 
statement disclosure, auditing scope or procedure, or any reportable events, 
which disagreements, if not resolved to the satisfaction of KPMG Peat Marwick 
LLP, would have caused it to make reference to the subject matter of such 
disagreements in connection with its reports.
        
        (c)   The reports of KPMG Peat Marwick LLP on the financial 
statements of the Company for the past two years contained no adverse opinion 
or disclaimer of opinion, and were not qualified or modified as to 
uncertainty, audit scope or accounting principles.
        
        (d)   The Company has not consulted with Ernst & Young LLP during the 
last two years or subsequent interim periods regarding either (i) the 
application of accounting principles to a specified transaction or 
transactions, either completed or proposed, or (ii) the type of audit opinion 
Ernst & Young LLP might render on the Company's financial statements.
        
        (e)   The Company has requested that KPMG Peat Marwick LLP furnish a 
letter addressed to the SEC stating whether they agree with the above 
statements.  A copy of the KPMG Peat Marwick LLP letter to the SEC, dated 
May 8, 1997, is filed as an exhibit to this Form 8-K.

Item 7. Financial Statements and Exhibits

         Exhibit

         16.1  Letter re change in Registrant's certifying accountants.
         


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                               SIGNATURES
                                           
                                           
Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned thereunto duly authorized.

                                    METRA BIOSYSTEMS, INC.



Date:  May 2, 1997                  By:  /s/ KURT E. AMUNDSON          
                                       ------------------------------------
                                         Kurt E. Amundson
                                         Chief Financial Officer
                                         (Duly Authorized and Principal 
                                         Financial and Accounting Officer)



                                   -3-
<PAGE>

                                METRA BIOSYSTEMS, INC.
                                           
                                  INDEX TO EXHIBITS
                                           
                                           

Exhibit Number             Description                  Sequential Page Number
- - - --------------             -----------                  ----------------------
    16.1          Letter re change in Registrant's                  5
                    certifying accountants.





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<PAGE>
                                                            EXHIBIT 16.1


                                     [LETTERHEAD]


May 8, 1997

Securities and Exchange Commission
Washington, DC 20549

Ladies and Gentlemen:

We were previously principal accountants for Metra Biosystems, Inc. and, 
under the date of July 18, 1996, we reported on the consolidated financial 
statements of Metra Biosystems, Inc. and subsidiaries as of and for the years 
ended June 30, 1996 and 1995. On May 2, 1997, our appointment as principal 
accountants was terminated. We have read Metra Biosystems, Inc.'s statements 
included under Item 4 of its Form 8-K dated May 2, 1997, and we agree with 
such statements, except that we are not in a position to agree or disagree 
with Metra Biosystems, Inc.'s statement that the change was recommended by 
the audit committee and approved by the board of directors, and that Ernst & 
Young was not engaged regarding the application of accounting principles to a 
specified transaction or the type of audit opinion that might be rendered on 
Metra Biosystems, Inc.'s financial statements.

Very truly yours,

/s/ KPMG Peat Marwick LLP

nc

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