METRA BIOSYSTEMS INC
SC 13D/A, 1998-07-14
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                         SCHEDULE 13D/A

NAME OF ISSUER:  METRA BIOSYSTEMS

TITLE OF CLASS OF SECURITIES:  COMMON STOCK

CUSIP NUMBER:    59114210

NAME, ADDRESS AND TELEPHONE NO:  KURT AMUNDSON, 265 NORTH WHISMAN ROAD,
MOUNTAIN VIEW, CA  94043   PH: 415-903-9100

DATE OF EVENT WHICH REQUIRES FILING OF THIS STATEMENT:  6/30/98

1.  NAME OF REPORTING PERSONS:  IRS: ID NOS. OF ABOVE PERSON:

     Thomas Mitchell Management Co., Inc. - 13-3589733

2.  CHECK BOX IF A MEMBER OF A GROUP    (B) x

3.  SEC use only

4.  Source of Funds     00

5.   Check if Disclosure of Legal Proceedings is Require Pursuant to Items
  2(d) or 2 (e) not sure - no proceedings.

6.   Citizenship or Place of Organization - State of Delaware

7.   Sole Voting Power -

8.   Shared Voting Power - Thomas Mitchell Mgt. Co., Inc. - 95,200
9.   Sole Dispositive Power - Thomas Mitchell Mgt. Co., Inc. - 95,200

10.  Shared Dispositive Power

11.  Aggregate Amount Beneficially Owned by Each Reporting Person 95,200

12.  Check if the Aggregate Amount in Row (11) Excludes Certain Shares

13.  Percent of Class Represented by Amount in Row (11)  0.75%

14.  Type of Reporting Person
  
     MITCHELL & HENRY, INC.-IA
  
CUSIP NO: 59114210
SCHEDULE 13D/A

ITEM #1-  METRA BIOSYSTEMS

ITEM #2-a-  Thomas Mitchell Management Co., Inc.
        b-  POB 31
            Lake Placid, NY  12946
        C-  Investment Advisor
        D-  During the last five years, Thomas Mitchell Management Co. has not
            been convicted in a criminal proceeding .
        E-  During the last five years, Thomas Mitchell management Co. has not
            been a party to a civil proceeding of a judicial or 
            administrative body of competent jurisdiction and as a result of
            such proceeding was or is subject to a judgment, decree or final
            order enjoining future violations of, or prohibiting or mandating 
            activities subject to, federal or state securities laws or 
            finding any violation with respect to such laws.

        F-   U.S.A.

ITEM #3-  Cash from Advisory Accounts

ITEM #4-   For Investment Purposes only.

ITEM #5a-  95,200/ 12,650,000 = 0.75%
       b- Thomas Mitchell Management Co., Inc. shared dispositive power
          and shared voting power.
       c- 10,400 shares recently purchased in various lots through
          NASDAQ and in negotiated transactions at prices from $2.06 -$2.40 
          per share.
       d- not applicable
       e- not applicable
ITEM #6-  not applicable
ITEM #7-  not applicable
  
  
  After reasonable inquiry and to the best of my knowledge and belief, I
  certify that the information set forth in this statement is true,
  complete and correct.
  
  Date:  July 14, 1998
  
  Signature:  Thomas S. Mitchell
  
  



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