INVESTMENT SERIES FUNDS INC
497, 1999-10-12
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                                                       - 4 -

INVESTMENT SERIES FUNDS, INC.
Federated Bond Fund
Supplement to Prospectus Dated December 31, 1998

I.       At a special meeting of shareholders to be held on November 30, 1999,
         shareholders of the above-named Fund will be asked to vote on the
         changes described below. If approved by shareholders, these changes
         will take effect on or after December 1, 1999. Shareholders will be
         notified if any of these changes are not approved at the special
         meeting or any adjournment thereof. Please keep this supplement for
         your records.

         Shareholders will be asked to consider the following proposals:

         (1)      To elect three Directors.

         (2) To make changes to the fundamental investment policies of the Fund:

                  (a)      To amend the Fund's fundamental investment policy
                           regarding borrowing money and issuing senior
                           securities to read as follows:

                           "The Fund may borrow money, directly or indirectly,
                           and issue senior securities to the maximum extent
                           permitted under the 1940 Act."

                  (b)      To amend the Fund's fundamental investment policy
                           regarding investments in real estate to read as
                           follows:

                           "The Fund may not purchase or sell real estate,
                           provided that this restriction does not prevent the
                           Fund from investing in issuers which invest, deal, or
                           otherwise engage in transactions in real estate or
                           interests therein, or investing in securities that
                           are secured by real estate or interests therein. The
                           Fund may exercise its rights under agreements
                           relating to such securities, including the right to
                           enforce security interests and to hold real estate
                           acquired by reason of such enforcement until that
                           real estate can be liquidated in an orderly manner."

                  (c)      To amend the Fund's fundamental investment policy
                           regarding investments in commodities to read as
                           follows:

                           "The Fund may not purchase or sell physical
                           commodities, provided that the Fund may purchase
                           securities of companies that deal in commodities."

                  (d)      To amend the Fund's fundamental investment policy
                           regarding underwriting securities to read as follows:

                           "The Fund may not underwrite the securities of other
                           issuers, except that the Fund may engage in
                           transactions involving the acquisition, disposition
                           or resale of its portfolio securities, under
                           circumstances where it may be considered to be an
                           underwriter under the Securities Act of 1933."

                  (e)      To amend the Fund's fundamental investment policy
                           regarding lending by the Fund to read as follows:

                           "The Fund may not make loans, provided that this
                           restriction does not prevent the Fund from purchasing
                           debt obligations, entering into repurchase
                           agreements, lending its assets to broker/dealers or
                           institutional investors and investing in loans,
                           including assignments and participation interests."

                  (f)      To amend the Fund's fundamental investment policy
                           regarding concentration of the Fund's investments in
                           the securities of companies in the same industry to
                           read as follows:

                           "The Fund will not make investments that will result
                           in the concentration of its investments in the
                           securities of issuers primarily engaged in the same
                           industry. Government securities, municipal securities
                           and bank instruments will not be deemed to constitute
                           an industry."

                  (g)      To amend, and to make non-fundamental, the Fund's
                           fundamental investment policy regarding buying
                           securities on margin to read as follows:

                           "The Fund will not purchase securities on margin,
                           provided that the Fund may obtain short-term credits
                           necessary for the clearance of purchases and sales of
                           securities, and further provided that the Fund may
                           make margin deposits in connection with its use of
                           financial options and futures, forward and spot
                           currency contracts, swap transactions and other
                           financial contracts or derivative instruments."

                  (h)      To amend, and to make non-fundamental, the Fund's
                           fundamental investment policy regarding pledging
                           assets to read as follows:

                           "The Fund will not mortgage, pledge, or hypothecate
                           any of its assets, provided that this shall not apply
                           to the transfer of securities in connection with any
                           permissible borrowing or to collateral arrangements
                           in connection with permissible activities."

         (3) To eliminate the Fund's fundamental investment policy regarding
selling securities short.

         (4)      To approve amendments to, and a restatement of, the Articles
                  of Incorporation for Investment Series Funds, Inc. (the
                  "Company"):

                  (a)      To require the approval of a "1940 Act" majority of
                           shareholders in the event of the sale or conveyance
                           of the assets of the Company to another corporation
                           or trust, to the extent permitted under Maryland law;
                           and

                  (b)      To permit the Board of Directors to liquidate assets
                           of the Company, or of a series or class, and
                           distribute the proceeds of such assets to the holders
                           of such shares representing such interests, without
                           seeking shareholder approval, to the extent permitted
                           under Maryland law.

II.      The following actions have been taken by the Board of Directors with
         regard to certain non-fundamental investment policies and limitations
         of the Fund:

         (1)      Approved the elimination of the Fund's non-fundamental
                  investment policy regarding writing call options and
                  purchasing put options.

         (2) Approved the elimination of the following undertakings for the
Fund:

                  "The Fund has no present intent to borrow money, sell
                  securities short, engage in foreign currency options, or
                  purchase financial futures contracts in excess of 5% of the
                  value of its net assets during the coming fiscal year."

         (3)      Approved the adoption of the following non-fundamental
                  investment limitations pertaining to concentration by the
                  Fund:

                  "(a) utility companies will be divided according to their
                  services (for example, gas, gas transmission, electric and
                  telephone will be considered a separate industry); (b)
                  financial service companies will be classified according to
                  the end users of their services (for example, automobile
                  finance, bank finance and diversified finance will each be
                  considered a separate industry); and (c) asset-backed
                  securities will be classified according to the underlying
                  assets securing such securities. To conform to the current
                  view of the SEC staff that only domestic bank instruments may
                  be excluded from industry concentration limitations, as a
                  matter of non-fundamental policy, the Fund will not exclude
                  foreign bank instruments from industry concentration
                  limitation tests so long as the policy of the SEC remains in
                  effect. In addition, investments in bank instruments, and
                  investments in certain industrial development bonds funded by
                  activities in a single industry, will be deemed to constitute
                  investment in an industry, except when held for temporary
                  defensive purposes. The investment of more than 25% of the
                  value of the Fund's total assets in any one industry will
                  constitute `concentration.'"

         (4)      Approved the adoption of the following non-fundamental
                  investment limitation for the Fund when applying its
                  commodities restriction:

                  "As a matter of non-fundamental policy, for purposes of the
                  commodities policy, investments in transactions involving
                  futures contracts and options, forward currency contracts,
                  swap transactions and other financial contracts that settle by
                  payment of cash are not deemed to be investments in
                  commodities."

         (5)      Approved the adoption of the following non-fundamental
                  investment limitation for the Fund regarding investing in
                  securities of other investment companies:

                  "The Fund may invest its assets in securities of other
                  investment companies, including securities of affiliated money
                  market funds, as an efficient means of carrying out its
                  investment policies and managing its uninvested cash."

III.     The Board of Directors approved the following restatement of the Fund's
         fundamental investment policy regarding diversification, without
         changing the meaning of the policy:

         "With respect to securities comprising 75% of the value of its total
         assets, the Fund will not purchase securities of any one issuer (other
         than cash; cash items; securities issued or guaranteed by the
         government of the United States or its agencies or instrumentalities
         and repurchase agreements collateralized by such U.S. government
         securities; and securities of other investment companies) if, as a
         result, more than 5% of the value of its total assets would be invested
         in the securities of that issuer, or the Fund would own more than 10%
         of the outstanding voting securities of that issuer."


                                                                October 12, 1999


Federated Investors

Federated Securities Corp., Distributor
Federated Investors, Inc.
Federated Investors Tower
1001 Liberty Avenue
Pittsburgh, PA  15222-3779

Cusip 461444309
Cusip 461444507
Cusip 461444606
Cusip 461444705

G02739-02 (10/99)





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