INVESTMENT SERIES FUNDS INC
24F-2NT, 1999-01-26
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                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 24F-2

                        ANNUAL NOTICE OF SECURITIES SOLD

                             PURSUANT TO RULE 24F-2

             READ INSTRUCTIONS AT END OF FORM BEFORE PREPARING FORM.

                              PLEASE PRINT OR TYPE.

1.   Name and address of issuer:

                          Investment Series Funds, Inc.

                               Federated Investors

                            Federated Investors Tower

                       Pittsburgh, Pennsylvania 15222-3779

2.   The name of each series or class of securities for which this Form is filed
     (If the Form is being filed for all series and classes of securities of the
     issuer, check the box but do not list series or classes): [ X ]

3.      Investment Company Act File Number:  811-07021

        Securities Act File Number:          33-48847

4(a). Last day of fiscal year for which this Form is filed: OCTOBER 31, 1998

4(b). [ ] Check box if this Form is being filed late (i.e., more than 90
     calendar days after the end of the issuer's fiscal year). (See Instruction
     A.2)

     NOTE: IF THE FORM IS BEING FILED LATE, INTEREST MUST BE PAID ON THE
REGISTRATION FEE DUE.

4(c). [ ] Check box if this is the last time the issuer will be filing this
     Form.


<PAGE>


5.      Calculation of registration fee:

        (i)    Aggregate sale price of securities sold during

               the fiscal year pursuant to section 24(f):   $587,766,427  

        (ii)   Aggregate price of securities redeemed or
               repurchased during the fiscal year:         $247,438,097

        (iii)  Aggregate price of securities redeemed or
               repurchased during any PRIOR fiscal year
               ending no earlier than October 11, 1995 that
               were not previously used to reduce registration
               fees payable to the Commission:                     $  0
                                                                    ---

        (iv)   Total available redemption credits [add Items 5(ii)
               and 5(iii)]:                                   --$247,438,097

        (v)    Net sales -- if Item 5(i) is greater than Item 5(iv)
               [subtract Item 5(iv) from Item 5(i)]:          $340,328,330

        (vi)   Redemption credits available for use in future years
               -- if Item 5(i) is less than Item 5(iv) [subtract
               Item 5(iv) from Item 5(i)]:                          $(0)

        (vii)  Multiplier for determining registration fee

               (See Instruction C.9):                         x    0.000278

        (viii) Registration fee due [multiply Item 5(v) by Item

               5(vii)] (enter "0" if no fee is due):          =$94,611

6.      Prepaid Shares

     If the response to item 5(i) was determined by deducting an amount of
     securities that were registered under the Securities Act of 1933 pursuant
     to rule 24e-2 as in effect before [effective date of rescisison of rule
     24e-2], then report the amount of securities (number of shares or other
     units) deducted here: -0-. If there is a number of shares or other units
     that were registered pursuant to rule 24e-2 remaining unsold at the end of
     the fiscal year for which this form is filed that are available for use by
     the issuer in future fiscal years, then state that number here: -0-.

7.   Interest due -- if this Form is being filed more than 90 days after the end
     of the issuer's fiscal year (see Instruction D): +$____________

8.   Total of the amount of the registration fee due plus any interest due [line
     5(viii) plus line 7]: =$ 94,611 -------

9.   Date the registration fee and any interest payment was sent to the
     Commission's lockbox depository: JANUARY 26, 1999

        Method of Delivery:
               [X]    Wire Transfer
               [   ]  Mail or other means


<PAGE>



                                   SIGNATURES

     This Form has been signed below by the following persons on behalf of the
issuer and in the capacities and on the dates indicated.

By (Signature and Title)*          

                      KEITH A. ANTLE, ASSISTANT TREASURER   

Date:

*       Please print the name and title of the signing officer below the
        signature.





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