INVESTMENT SERIES FUNDS, INC.
Federated Investors Funds
5800 Corporate Drive
Pittsburgh, Pennsylvania 15237-7000
December 30, 1999
EDGAR Operations Branch
Securities and Exchange Commission
Division of Investment Management
450 Fifth Street, Northwest
Washington, DC 20549
RE: INVESTMENT SERIES FUNDS, INC. (the "Corporation")
Federated Bond Fund (the "Fund")
1933 Act File No. 33-48847
1940 Act File No. 811-07021
Dear Sir or Madam:
Pursuant to Rule 497(j) under the Securities Act of 1933, the
above-named Corporation hereby certifies that the definitive forms of
prospectuses and statement of additional information of the Fund, dated December
31, 1999, that would have been filed under Rule 497(c), do not differ from the
forms of prospectuses and statement of additional information of the Fund
contained in the most recent registration statement for the Corporation. This
registration statement was electronically filed under Rule 485(b) as
Post-Effective Amendment No. 19 on December 29, 1999.
If you have any questions regarding this certification, please call me
at (412) 288-8160.
Very truly yours,
/s/ C. Grant Anderson
C. Grant Anderson
Assistant Secretary