LIFE MEDICAL SCIENCES INC
S-8, 2000-01-21
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
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        As filed with the Securities and Exchange Commission on January 21, 2000
                                                           Registration No.
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                             ----------------------
                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                            ------------------------
                           LIFE MEDICAL SCIENCES INC.
             (Exact name of registrant as specified in its charter)

           Delaware                                              14-1745197
(State or other jurisdiction of                               (I.R.S. employer
 incorporation or organization)                              identification no.)

                               379 Thornall Street
                            Edison, New Jersey 08837
               (Address of principal executive offices) (Zip code)
                             -----------------------

                LIFE MEDICAL SCIENCES, INC. AMENDED AND RESTATED
                             1992 STOCK OPTION PLAN
                            (full title of the plan)

                            Mr. Robert P. Hickey, CEO
                           Life Medical Sciences, Inc.
                               379 Thornall Street
                            Edison, New Jersey 08837
                     (Name and address of agent for service)
                                 (732) 494-0444
          (Telephone number, including area code, of agent for service)

                             -----------------------
                                    Copy to:
                            Irwin M. Rosenthal, Esq.
                               Graham & James LLP
                          885 Third Avenue, 21st Floor
                            New York, New York 10022
                                 (212) 848-1000

                             -----------------------
                         Calculation of Registration Fee

<TABLE>
<CAPTION>
- -----------------------------------------------------------------------------------------------------------------------
Title of securities to be      Amount to be         Proposed maximum           Proposed maximum           Amount of
       registered             registered (1)    offering price per unit    aggregate offering price    registration fee
- -----------------------------------------------------------------------------------------------------------------------
<S>                              <C>                    <C>                        <C>                      <C>
Common Stock ($.001 par          290,020(2)             $0.344(4)                  $ 99,767                 $26.34
value per share)
- -----------------------------------------------------------------------------------------------------------------------
Common Stock                       6,000(3)             $0.400                     $  2,400                 $ 0.63
- -----------------------------------------------------------------------------------------------------------------------
Common Stock                       3,000(3)             $0.500                     $  1,500                 $ 0.40
- -----------------------------------------------------------------------------------------------------------------------
Common Stock                     200,980(3)             $0.562                     $112,951                 $29.82
- -----------------------------------------------------------------------------------------------------------------------
           TOTAL                 500,000                                           $216,618                 $57.19
- -----------------------------------------------------------------------------------------------------------------------
</TABLE>

(1)   Pursuant to Rule 416, this Registration Statement also covers such
      indeterminable number of additional shares as may become issuable pursuant
      to terms designed to prevent dilution resulting from stock splits, stock
      dividends or similar events.
(2)   Represents shares of common stock reserved for issuance pursuant to
      options available for grant under the registrant's Amended and Restated
      1992 Stock Option Plan ("Option Plan"), which shares have been made
      available pursuant to an increase in the total authorized shares under the
      Option Plan from 907,500 to 1,407,500.
(3)   Represents shares of common stock issuable upon exercise of options
      granted under the Option Plan, which shares have been made available
      pursuant to the increase in authorized shares under the Option Plan.
(4)   Calculated on the basis of the average of the closing bid and ask prices
      as of January 13, 2000 in accordance with Rule 457(h).
<PAGE>

                                EXPLANATORY NOTE

      Pursuant to Rule 428(b) (1) under the Securities Act of 1933, as amended
(the "Securities Act"), an information statement will be distributed to holders
of options granted under the Life Medical Sciences, Inc. Amended and Restated
1992 Stock Option Plan. The information statement and the documents incorporated
by reference in this registration statement pursuant to Item 3 of Part II of the
Form S-8 registration statements referred to below, taken together, constitute a
prospectus that meets the requirements of the Securities Act.

           INCORPORATION OF CONTENTS OF PRIOR REGISTRATION STATEMENTS

      Except as modified herein, the contents of the registrant's registration
statement on Form S-8, Registration No. 33-60580, as amended by the registrant's
registration statement on Form S-8, Registration No. 333-03895, are incorporated
by reference herein.

                     INTERESTS OF NAMED EXPERTS AND COUNSEL

      Certain legal matters in connection with the issuance of the shares of
Common Stock, par value $.001 per share, of the registrant being registered
hereby are being passed upon by Graham & James LLP, 885 Third Avenue, New York,
New York 10022, counsel to the registrant. Irwin M. Rosenthal, a member of such
firm, serves as an officer and a director of the registrant. Mr. Rosenthal
directly owns 2,704 shares of Common Stock of the registrant and may be deemed
to beneficially own, directly or indirectly, 682,940 shares of Common Stock of
the registrant, including 255,940 shares of Common Stock issuable upon exercise
of options which are currently exercisable. In addition, other members of Graham
& James LLP may be deemed to beneficially own additional shares of Common Stock
of the registrant.


                                       2
<PAGE>

                                    EXHIBITS

      The following is a complete list of exhibits filed as a part of this
registration statement:

      Exhibit No.                                 Document
      -----------                                 --------

         4.1                 Amended and Restated 1992 Stock Option Plan of the
                             registrant. (Incorporated by reference to Exhibit
                             10.1 contained in Amendment No. 2 to the
                             registrant's registration statement, on Form S-1,
                             Registration No. 33-02588.

         4.2                 Specimen Stock Certificate. (Incorporated by
                             reference to Exhibit 2 contained in the
                             registrant's registration statement on Form S-1,
                             Registration No. 33-49008).

         4.3                 Form of Incentive Stock Option Agreement under the
                             Option Plan (Incorporated by reference to Exhibit
                             4.4 contained in registrant's registration
                             statement on Form S-8, Registration No. 333-03895).

         4.4                 Form of Non-Qualified Stock Option Agreement under
                             the Option Plan (Incorporated by reference to
                             Exhibit 4.5 contained in registrant's registration
                             statement on Form S-8, Registration No. 333-03895).

         5.1                 Opinion of Graham & James LLP.

        23.1                 Consent of Graham & James LLP. (Included in
                             Exhibit 5.1).

        23.2                 Consent of Richard A. Eisner & Company, LLP.

        24.1                 Powers of Attorney. (Included on the signature page
                             of this Registration Statement).


                                       3
<PAGE>

                                   SIGNATURES

      Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of New York, State of New York, on January 13, 2000.

                 LIFE MEDICAL SCIENCES, INC.


                 By: /S/ Robert P. Hickey
                     ------------------------
                         Robert P. Hickey
                         CEO, President and Chairman of the Board of Directors

      KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below constitutes and appoints each of Robert P. Hickey and Irwin M. Rosenthal
his true and lawful attorney-in-fact and agent, each acting alone, with full
powers of substitution and resubstitution, for him and his name, place and
stead, in any and all capacities, to sign any and all amendments to this
registration statement, and to file the same, with all exhibits thereto, and
other documents in connection therewith, with the Securities and Exchange
Commission, and to make any and all state securities law or blue sky filings,
granting unto said attorney-in-fact and agents, each acting alone, full power
and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully for all intents and
purposes as he might or could do in person, hereby ratifying and confirming all
that said attorney-in-fact and agents, each acting alone, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.

      Pursuant to the requirements of the Securities Act of 1933, this
registration statement has been signed by the following persons in the
capacities and on the dates indicated.

       Signature                           Title                      Date
       ---------                           -----                      ----


/S/ Robert P. Hickey       CEO, President and Chairman of       January 13, 2000
- -----------------------    the Board of Directors (principal
    Robert P. Hickey       executive officer and acting
                           principal financial and accounting
                           officer)


/S/ Irwin M. Rosenthal     Secretary and Director               January 14, 2000
- -----------------------
    Irwin M. Rosenthal


/S/ Coy Eklund             Director                             January 13, 2000
- -----------------------
    Coy Eklund


                           Director                             January __, 2000
- -----------------------
    Joel L. Gold


/S/ Walter R. Maupay       Director                             January 12, 2000
- -----------------------
    Walter R. Maupay


/S/ Edward A. Celano       Director                             January 11, 2000
- -----------------------
    Edward A. Celano


                                       4



January 14, 2000

Life Medical Sciences, Inc.
379 Thornall Street
Edison, New Jersey 08837

Ladies and Gentlemen:

            We have acted as counsel to Life Medical Sciences, Inc., a Delaware
corporation (the "Company"), in connection with the preparation of its
Registration Statement on Form S-8 under the Securities Act of 1933, as amended
(the "Registration Statement"), to which this opinion is to be filed as an
exhibit. The Registration Statement relates to the issuance of up to an
aggregate of 500,000 shares (the "Plan Shares") of the Company's common stock,
par value $.00l per share (the "Common Stock"), pursuant to stock options
granted or available for grant under the Company's Amended and Restated 1992
Stock Option Plan (the "Plan").

            Based upon the foregoing, and having regard for such legal
considerations as we deem relevant, we are of the opinion that the Plan Shares,
when issued in accordance with the terms and conditions of the Plan, will be
legally issued, fully paid and nonassessable.

            We hereby consent to the filing of this opinion as an exhibit to the
Registration Statement. In giving this consent, we do not thereby admit that we
are in the category of persons whose consent is required under Section 7 of the
Securities Act of 1933, as amended, and the rules and regulations of the
Securities and Exchange Commission thereunder.

                                Very truly yours,

                               GRAHAM & JAMES LLP



                              ACCOUNTANTS' CONSENT

      We consent to the incorporation by reference in this Registration
Statement on Form S-8 of Life Medical Sciences, Inc., of our report dated March
2, 1999 on our audit of the financial statements of Life Medical Sciences, Inc.,
included in the December 31, 1998 Annual Report on Form 10-K of Life Medical
Sciences, Inc.

                                          Richard A. Eisner & Company, LLP
                                          Certified Public Accountants

New York, New York
January 20, 2000



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