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Consent of Independent Certified Public Accountants
We have issued our report dated July 14, 2000 accompanying the financial
statements of Insured Municipals Income Trust, 121st Insured Multi-Series as of
May 31, 2000, and for the period then ended, contained in this Post-Effective
Amendment No. 8 to Form S-6.
We consent to the use of the aforementioned report in the Post-Effective
Amendment and to the use of our name as it appears under the caption "Auditors".
Grant Thornton LLP
Chicago, Illinois
September 25, 2000