INTERNATIONAL NURSING SERVICES INC
8-K, 1997-12-24
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                                 UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549
                                   FORM 8-K

                                CURRENT REPORT
                 PURSUANT TO SECTION 13 OR 15(D) OF THE
                     SECURITIES EXCHANGE ACT OF 1934

                    Date of Report: December 10, 1997

                   INTERNATIONAL NURSING SERVICES, INC
          (Exact name of registrant as specified in its charter)

         Colorado              000-24768               84-1123311
(State or other jurisdiction  (Commission             (IRS Employer
    of incorporation)         File Number)         Identification No.)

        360 South Garfield Street, Suite 400, Denver, Colorado    80209
                   (Address of principal executive offices)     (Zip Code)

      Registrant's telephone number, including area code:  (303) 393-1515


                                      None
          (Former name or former address, if changes since last report)

Item 1. Changes in Control of Registrant.  N/A.
Item 2 . Acquisition or Disposition of Assets.

On  November  17,  1997,  International Nursing Services, Inc. (the "Company")
entered  into  an  Agreement and Plan of Merger (the "Agreement") with Cymedix
Corporation, a California corporation ("Cymedix"), engaged in the  development
of  medical  information  software,  and  the  Company's  own  wholly-owned
subsidiary,  Cymedix  Lynx  Corporation,  a  Colorado  corporation  (the
"Subsidiary").  Upon approval of the shareholders of Cymedix and certain other
closing  conditions  set  forth  in the Agreement, Cymedix will merge into the
Subsidiary,  and  the Company will issue 6,980,000 shares of it's Common Stock
to  the shareholders of Cymedix and grant options covering 1,200,000 shares of
the Company's Common Stock to employess of Cymedix.  On December 10, 1997, the
Company  was informed by Cymedix that the shareholders of Cymedix had approved
the  merger.   It is expected that the Cymedix acquisition will close in early
January of 1998.  Since July, 1997, the Company has advanced loans aggregating
to  $297,500  to  Cymedix  to be used as working capital.  Such amount and any
further  amount that the Company advances to Cymedix prior to the closing will
become  an  inter-company  receivable and part of the Company's purchase price
for  the  acquired  business.    At the closing price for the Company's Common
Stock  on  the  Nasdaq  SmallCap Market on December 18, 1997, the shares to be
issued  as  consideration for the acquisition had a value of $1,090,625.  Such
shares  shall  be  issued  to  19 persons, who are the current shareholders of
Cymedix,  in  a  private  transaction.    The  Company  has  agreed  to file a
registration  statement  with  the  U.S. Securities and Exchange Commission by
April  20,  1998,  to  register such shares to permit them to be sold into the
public market.  The Company has agreed to employ the President of Cymedix, who
is  its  largest  shareholder,  and  one  other  Cymedix  employee pursuant to
employment  agreements,  which  shall  be finalized prior to the closing.  The
Company  expects to employ six other Cymedix employees but not under contract.
In  addition  the  President  of  Cymedix  will  have the right to designate a
nominee  for  election  as  director  of the Company for three years after the
closing.

Item 3. Bankruptcy or Receivership.  N/A.

   Item 4. Changes in Registrant's Certifying Accountant.  N/A.
   Item 5. Other Events.  Press Relase, dated December 22, 1997, announcing
           the approval of the acquisition of
           Cymedix Corporation by International
           Nursing Services, Inc.

Item  6.  Resignations  of  Registrant's  Directors.    N/A.
Item  7.  Financial  Statements  and  Exhibits.
          List  below  the  financial  statements,  pro  forma  financial
          information  and  exhibits,  if  any,  filed  as  part  of
          this  report:

(a)       The required financial statements of the business acquired shall by
          filed  with an amendment to this Form 8-K within sixty days of the 
          date of the filing  of  this  Form  8-K

(b)       The required pro forma financial information shall be filed with an
          amendment  to  this Form 8-K within sixty days of the filing of this
          Form 8-K.

(c)       Exhibits
          Exhibit 2.1   Agreement and Plan of Merger among Cymedix
                        Corporation,  a  California  corporation,
                        International  Nursing  Services,
                        Inc.,  a  Colorado  corporation  and  Cymedix  Lynx
                        Corporation,  a Colorado corporation

          Exhibit 2.2   Amendment No.1 to Agreement and Plan of
                        Merger  among  the  same  parties.

          Exhibit 99.1  Press Release announcing the approval of
                        the  acquisition  of  Cymedix  Corporation  by
                        International  Nursing  Services, Inc.



Item  8.    Change  in  Fiscal  Year.    N/A.
Item  9.    Sales  of  Equity  Securities  Pursuant  to  Regulation S.  N/A.

                                  SIGNATURES
     Pursuant  to the requirements of the Securities Exchange Act of 1934, the
registrant  has  duly  caused  this  report  to be signed on its behalf by the
undersigned  hereunto  duly  authorized.


                  INTERNATIONAL  NURSING  SERVICES,  INC.


Date:  December  22, 1997              By:   /s/ John P. Yeros
                                             ------------
                                             John  P.  Yeros,  President
                                             and  Chief  Executive  Officer







          EXECUTION  COPY

                         AGREEMENT AND PLAN OF MERGER



     This Agreement and Plan of Merger is entered into as of November 17, 1997
among  INTERNATIONAL  NURSING  SERVICES,  INC.,  a  Colorado  corporation
(collectively with its subsidiaries, the ACompany@), CYMEDIX LYNX CORPORATION,
a  Colorado  corporation  wholly  owned  by the Company (the AMerger Sub@) and
CYMEDIX  CORPORATION,  a  California  corporation  (ACymedix@).

                             PRELIMINARY STATEMENt

     1.        The Company and Cymedix are parties to a letter of intent dated
July  23,  1997  (the  ALetter  of  Intent@)  outlining the proposed terms and
conditions  for  the merger (the AMerger@) of Cymedix with and into the Merger
Sub  and providing for a series of convertible loans (the ABridge Loans@) from
the  Company  to Cymedix pending implementation of the Merger.  The Merger Sub
will be the surviving corporation in the Merger, and the operations of Cymedix
will  be  conducted  through  the  Merger  Sub  following  the  Merger.

     2.        As a result of the Merger, (a) the outstanding capital stock of
Cymedix  will  be converted into common stock, $.001 par value, of the Company
(ACompany  Common  Stock@),  (b) the outstanding stock options and convertible
debt  of  Cymedix  will  be exercisable for or convertible into Company Common
Stock and (c) the Merger Sub will succeed to all the assets and liabilities of
Cymedix.    The  Merger  is  intended  to be treated as a reorganization under
section  368(a) of the Internal Revenue Code of 1986, as amended (the ACode@).

     3.         Pursuant to the Merger, a total of 6,980,000 shares of Company
Common Stock (the AMerger  Shares@) will be issued in exchange for the capital
stock of Cymedix issued and outstanding at the time off the Merger or reserved
for  issuance  upon  the  exercise of outstanding stock options assumed in the
Merger.    The  total  number of Merger Shares will not be affected by (a) any
exercise  of  those  stock  options  before  or  after  the  Merger or (b) any
fluctuations  in the market price of Company Common stock prior to the Merger.

     4.       The boards of directors of the Company (the ACompany Board@) and
the  Merger  Sub  (the  AMerger  Sub  Board@)  have  unanimously approved this
Agreement, and the Company has determined that no approval by its shareholders
is  required  for  consummation  of  the  Merger.

     5.          The  board  of directors of Cymedix (the ACymedix Board@) has
unanimously  approved this Agreement and recommended its approval and adoption
by the shareholders of Cymedix, voting as separate classes, by written consent
to be solicited by the Cymedix Board as promptly as practicable after the date
hereof.

     6.       The Merger will be effected pursuant to separate certificates of
merger  (the  ACertificates  of  Merger@)  reflecting  the terms of the Merger
provided  herein  and  all  provisions  required  by  applicable  law.

     NOW,  THEREFORE,  in  consideration  of  the  premises  and  the  mutual
agreements, covenants and conditions provided herein, the parties hereto agree
as  follows:

<PAGE>


     ARTICLE  I  DEFINITIONS

     1.1     DEFINITIONS.  As used in this Agreement and the Schedules hereto,
the  following  terms  have  the  respective  meanings  set  forth  below:

     Affiliate  means,  with  respect  to  any Person, any other Person that
directly  or  indirectly controls, is controlled by or is under common control
with  the  Person  in  question.

     Agreement means this Agreement and Plan of Merger, as amended from time
to  time  in  accordance  with  Section  8.1.

     Benefit  Plans  means  Aemployee  pension benefit plans,@ as defined in
section  3(2) of ERISA (APension Plans@), Aemployee welfare benefit plans,@ as
defined in section 3(1) of ERISA, bonus, stock option, stock purchase, phantom
stock  and other equity, deferred compensation plans or arrangements and other
employee  fringe  benefit  plans.

     Bridge  Loans means the convertible loans that the Company has advanced
and undertaken to advance to Cymedix during the Bridge Period in the aggregate
principal  amount  of  up  to  $297,500  in  accordance  with  Section  6.1.

     Bridge  Loan  Commitment  means  the  Company=s  obligation to make the
Bridge  Loans.

     Bridge  Loan  Funding  Schedule  has  the  meaning set forth in Section
6.1(a).

     Bridge  Notes  means  the convertible promissory notes issued and to be
issued  by Cymedix to evidence the Bridge Loans in the form annexed as Exhibit
A  to  the  Letter  of  Intent.

     Bridge  Period  means  the  period of up to 145 days from July 23, 1997
through the Effective Date, during which the Company has undertaken to provide
the  Bridge  Loans  to  Cymedix.

     California  Act  means  the  California  General  Corporation  Law,  as
amended.

     Certificates  of  Merger  means  the articles or certificates of merger
relating  to  the Merger, to be prepared and filed in accordance with the laws
of  the  States  of  Colorado  and  California.

     Code  means  the  Internal  Revenue  Code  of  1986,  as  amended.

     Closing  has  the  meaning  set  forth  in  Section  2.1(b).

     Colorado  Act  means the Colorado Business Corporation Act, as amended.

     Common  Exchange Rate has the meaning set forth in Section 2.2(b)(iii).

     Company  means  International  Nursing  Services,  Inc.,  a  Colorado
corporation.    Unless  the  context otherwise requires, all references to the
Company  in  this  Agreement  also  include  all  of  its  Subsidiaries.

     Company  Board  means  the  board  of  directors  of  the  Company.
ACompany  Balance  Sheet@  means the consolidated balance sheet of the Company
set  forth  in  its most recent SEC Document filed prior to the date hereof on
Form  10-KSB  or  Form  10-QSB.

     Company  Common  Stock  means the common stock, $.001 par value, of the
Company.

     Company  Contracts  has  the  meaning  set  forth  in  Section  5.9.

     Company Intellectual Property has the meaning set forth in Section 5.8.

     Company  Preferred Stock means preferred stock, $1.00 par value, of the
Company.

     Company  Termination Event has the meaning set forth in Section 8.2(a).

      Competing Proposal means an unsolicited, bona fide written proposal to
the  Cymedix  Board,  Cymedix or its shareholders that is not conditioned upon
obtaining  financing  and  provides  for  greater value to the shareholders of
Cymedix  than  the  consideration  contemplated  by  the  Merger.

     Competing  Transaction  means  any  merger,  sale  of assets or similar
transaction involving Cymedix, other than the Merger, or other transaction the
consummation  of  which  could  be  expected to impede, delay, interfere with,
prevent  or  dilute  the  benefits  of  the  Merger  to  the  Company.

     Confidential  Information  means,  with  respect to each party, (a) all
information  concerning  the  business  and  affairs  of that party, including
financial  information, business plans and strategies, technology, proprietary
information, know-how, formulae, products, methods and operational information
and  techniques,  (b) any information that the party is required by applicable
law  to  preserve  in  confidence  and  (c)  any  other information reasonably
identified  by  a  party to the other party as confidential, but excluding (i)
information  known by the other party or generally available to the healthcare
industry  or  in  the  public  domain, (ii) information that was independently
developed by the other party without the use of the first party=s Confidential
Information and (iii) information rightfully provided by a third party without
continuing  restrictions  on  its  use.

     Cymedix  means  Cymedix  Corporation,  a  California  corporation.

     Cymedix  Board  means  the  board  of  directors  of  Cymedix.

     Cymedix  Budget means the Marketing Rollout Budget heretofore delivered
by  Cymedix  to  the  Company.

     Cymedix  Balance  Sheet  has  the  meaning set forth in Section 4.6(b).

     Cymedix  Common Stock means the common stock, no par value, of Cymedix.

     Cymedix  Contracts  has  the  meaning  set  forth  in  Section  4.9.

     Cymedix Intellectual Property has the meaning set forth in Section 4.8.

     Cymedix  Option Plans means the Nonqualified Stock Option Plans adopted
by  Cymedix  in  1996  and  1997.

     Cymedix  Preferred  Stock  means  Cymedix  Series A Preferred Stock and
Cymedix  Series  B  Preferred  Stock,  collectively.

     Cymedix Series A Preferred Stock means the series A preferred stock, no
par  value,  of  Cymedix.

     Cymedix Series B Preferred Stock means the series B preferred stock, no
par  value,  of  Cymedix.

     Cymedix  Stock  Options  means  stock  options issued under the Cymedix
Option  Plans  and  outstanding  as  of  the  date  of  this  Agreement.

     Cymedix  Termination  Event  has  the mean set forth in Section 8.2(b).

     Diligence Period means the portion of the Bridge Period ending ten days
after  the  date  of  this  Agreement.

     Effective  Date  has  the  meaning  set  forth  in  Section  1.1.

     Employment  Agreements  has  the  meaning  set  forth  in  Section 6.9.

     Environmental  Laws  means  any  and  all  applicable  treaties,  laws,
regulations,  enforceable  requirements,  binding  determinations,  orders,
decrees, judgments, injunctions, permits, approvals, authorizations, licenses,
variances,  permissions,  notices or binding agreements issued, promulgated or
entered  into  by  any  Governmental  Authority  relating  to the environment,
including the Comprehensive Environmental Response, Compensation and Liability
Act of 1980, as amended by the Superfund Amendments and Reauthorization Act of
1986  (CERCLA),  42  U.S.C.    9601  et  seq., the Federal Water Pollution
                                         --  ----
Control  Act,  as amended by the Clean Water Act of 1977, 33 U.S.C.  1251 et
                                                                          --
seq.,  Clean Air Act of 1970, as amended, 42 U.S.C.  7401 et seq., the Toxic
 ---                                                      -- ----
Substances  Control  Act  of 1976, 15 U.S.C.  2601 et seq., the Occupational
                                                   -- ----
Safety  and  Health  Act  of  1970,  as amended, 29 U.S.C.  651 et seq., the
                                                                -- ----
Emergency Planning and Community Right-to-Know Act of 1986, 42 U.S.C.  11001
et  seq.,  and  any  similar  or  implementing  state  or  local  law, and all
- --  ----
amendments  or regulations promulgated thereunder.  As used in this Agreement,
- -- ----
the  term  AHazardous  Materials@  means  all materials or chemicals regulated
pursuant  to  any  Environmental  Law.

     ERISA  means  the  Employee  Retirement Income Security Act of 1974, as
amended.

     Exchange  Act  means  the  Securities Exchange Act of 1934, as amended.

     Exchange  Agent  means American Stock Transfer & Trust Company, Inc., a
Colorado  banking  corporation  that  also  serves  as  transfer agent for the
Company  Common  Stock.

     Global  Note  means  the  convertible  promissory note in the principal
amount  of  $250,000  issued  by  Cymedix  to  Global  Med  Technologies, Inc.

     Governmental  Authority  means  any  federal,  state,  local or foreign
government  or  any  court of competent jurisdiction, administrative agency or
commission  or  other  governmental  authority or instrumentality, domestic or
foreign.

     Holders  has  the  meaning  set  forth  in  Section  6.10(a).

     Letter of Intent means the letter from the Company to the Cymedix Board
dated  July  23,  1997 setting forth the Company=s proposal for the Merger and
the  Bridge  Loans.

     Management  Options  has  the  meaning  set  forth  in  Section  6.9.

     Material  Adverse  Effect  means  a  material  adverse  effect  on  the
business, assets, condition (financial or otherwise), results of operations or
prospects  of  a  party  to  this  Agreement  or  the  ability of the party to
consummate  the  transactions  contemplated  by  this  Agreement.

     Merger  means the merger of Cymedix with and into the Merger Sub on the
terms  and  conditions  provided  in  this  Agreement.

     Merger Share Market Price means $.375, representing the average closing
price  of  Company  Common  Stock  during  the  five  trading days immediately
preceding  the  date  hereof.

     Merger Shares means a total of 6,980,000 shares of Company Common Stock
to  be  issued  pursuant  to  the  Merger in exchange for the capital stock of
Cymedix  (a)  outstanding  on the Effective Date and (b) reserved for issuance
upon  the  exercise  of  Cymedix  Stock  Options  assumed  in  the  Merger.

     Merger  Sub  means  Cymedix  Lynx  Corporation,  a Colorado corporation
wholly  owned by the Company and organized for the purpose of effectuating the
Merger.

     Merger  Sub  Board  means  the  board  of  directors of the Merger Sub.

     Old  Stock  Certificate  has  the  meaning set forth in Section 3.3(a).

     Optionees  has  the  meaning  set  forth  in  Section  6.9.

     Permitted  Liens  has the meaning set forth in Section 4.7 with respect
to  Cymedix  and  Section  5.7  with  respect  to  the  Company.

     Person  means an individual, any form of business enterprise, including
a  corporation, limited liability company, partnership or limited partnership,
and  any  other  juridical  entity  or  its representative, including a trust,
trustee, estate, custodian, administrator, personal representative, nominee or
any  other  entity  acting  on its own behalf or in a representative capacity.

     Predecessor  Entity  means  a  Person  to  which  another  Person  is a
successor  issuer  for  purposes  of  Rule  12g-3  under  the  Exchange  Act.

     Registration  Statement  has  the meaning set forth in Section 6.10(a).

     Reserved  Merger  Shares  has  the meaning set forth in Section 2.2(c).

     SEC  means  the  United  States  Securities  and  Exchange  Commission.

     SEC  Documents  has  the  means  set  forth  in  Section  5.6.

     Securities  Act  means  the  Securities  Act  of  1933,  as  amended.

     Series  A  Preferred Exchange Rate has the meaning set forth in Section
2.2(b)(i).

     Series  B  Preferred Exchange Rate has the meaning set forth in Section
2.2(b)(ii).

     Subsidiary  means  each  Person  of  which (a) a majority of the voting
power of the voting equity securities or equity interest is owned, directly or
indirectly,  by  another  Person.

     Tax  or  Taxes  means all federal, state, local and foreign taxes and
assessments,  including  all  interest,  penalties  and additions imposed with
respect  thereto.

     1.2       CONSTRUCTION.  Whenever the context requires, the gender of all
words  used  in  this  Agreement  includes the masculine, feminine and neuter.
Unless  otherwise  expressly  provided  herein,  all  references  to Articles,
Sections and Schedules refer to articles, sections and schedules of or to this
Agreement.   All  Schedules are hereby incorporated in and made a part of this
Agreement  as  if set forth in full herein.  The headings and captions in this
Agreement  and  the  Schedules are for convenience and identification only and
are in no way intended to define, limit or expand the scope and intent of this
Agreement  or  any  provision  hereof.

     ARTICLE  II  C  THE  MERGER

     2.1        FILING OF CERTIFICATES OF MERGER AND CLOSING.  (a)  The Merger
will  become  effective  on the date the Certificates of Merger are filed with
the  Secretaries  of  State  of  the  States  of  Colorado  and  California in
accordance  with  applicable  law  or  any  subsequent  date  specified in the
Certificates  of  Merger  as  the effective date of the Merger (the Effective
Date).    The Certificates of Merger will be filed as promptly as practicable
after  the  receipt  of the requisite consents by the shareholders of Cymedix,
provided  that  the conditions set forth in Article VII have been satisfied or
waived  where  permitted.

     (b)        The closing of the transactions contemplated by this Agreement
(the Closing) will be held at the offices of the Company, 360 South Garfield
Street  -  Suite  400,  Denver,  Colorado  80209-3136,  or  at any alternative
location  designated  by  the  parties  hereto.

     2.2    THE   MERGER.  (a)  On the Effective Date, Cymedix will merge with
and  into  the  Merger  Sub, and the separate existence of Cymedix will cease.
The Merger Sub will be the surviving entity in the Merger and will continue to
be  governed  by  the  laws  of  the  State  of  Colorado.  The Certificate of
Incorporation  and Bylaws of the Merger Sub in effect as of the Effective Date
will  not  be  affected  by  the  Merger  and  will  be  the  Certificate  of
Incorporation  and  Bylaws  of  the  surviving  corporation.

     (b)          On the Effective Date, without any action on the part of the
holders  thereof,  the  capital  stock  of  Cymedix  issued  and  outstanding
immediately  prior  to  the Effective Date will be converted into the right to
receive  Company  Common  Stock  as  follows:

     (i)     Series A Preferred Exchange Rate.  Each share of Cymedix Series A
             --------------------------------
Preferred  Stock  will  be  converted into 15,200 Merger Shares (the Series A
Preferred  Exchange  Rate).    The  Series  A  Preferred  Exchange  Rate  was
determined  by  dividing (A) $5,700.00, representing the estimated liquidation
value of each share of Cymedix Series A Preferred Stock on the Effective Date,
by  (B)  the  Merger  Share  Market  Price.

     (ii)      Series B Preferred Exchange Rate.  Each share of Cymedix Series
               --------------------------------
B  Preferred  Stock will be converted into 6.0267 Merger Shares (the Series B
Preferred  Exchange  Rate).    The  Series  B  Preferred  Exchange  Rate  was
determined by dividing (A) $2.26, representing the estimated liquidation value
of  each  share  of Cymedix Series B Preferred Stock on the Effective Date, by
(B)  the  Merger  Share  Market  Price.

     (iii)      Common Exchange Rate.  Each share of Cymedix Common Stock will
                --------------------
be converted into the number of Merger Shares (the Common Exchange Ratio) to
be  determined  as  of the Effective Date by dividing (A) the number of Merger
Shares  remaining  after deducting therefrom the Merger Shares issuable in the
Merger in exchange for the Cymedix Series A Preferred Stock and Cymedix Series
B  Preferred  Stock  issued  and  outstanding at the Effective Date by (B) the
total  number  of  shares of Cymedix Common Stock outstanding on the Effective
Date  and  issuable  upon exercise of Cymedix Stock Options outstanding on the
Effective  Date.

     (c)       After the Effective Date, any Cymedix Stock Options that remain
unexercised  on  the Effective Date will be exercisable for Merger Shares (the
Reserved  Merger  Shares)  based on the Common Exchange Rate, as provided in
Section 6.7(a).  Insofar as (i) the Global Note to be assumed in the Merger is
not  convertible into Cymedix Common Stock in the absence of a payment default
thereon  and (ii) the Company cannot convert the Bridge Notes if the Merger is
consummated,  the  shares  of Cymedix Common Stock issuable upon conversion of
those  instruments  are  not  included  in  the  Reserved  Merger  Shares.

     (d)        The shareholders of Cymedix will not be entitled to fractional
Merger  Shares  as  a  result  of the Merger, and the holders of Cymedix Stock
Options that remain unexercised on the Effective Date  will not be entitled to
any  fractional  Reserved Merger Shares upon exercise thereof.  Any fractional
share  of  Company  Common  Stock  that may result from the application of the
exchange  rates  in  Section 2.2(b) shall be rounded up or down to the nearest
whole  Merger Share, and any fractional share of Company Common Stock that may
result  from  the application of the exchange rates in Section 2.2(c) shall be
rounded  up  or  down  to  the  nearest  whole  Reserved  Merger  Share.

     (e)          The  Merger shall have all the other effects provided by the
Colorado  Act  and  the  California  Act.

     2.3        CHANGE IN STRUCTURE OF MERGER.  If the parties determine after
the  date  hereof that a change in the structure of the Merger is necessary or
desirable  to  make  the transaction tax free to shareholders of Cymedix or to
comply  with  applicable  law,  the  parties  shall  cooperate in making those
changes  in  this  Agreement,  the  Certificates of Merger and other documents
contemplated  hereby  and  in  taking any other actions required to effectuate
those  changes,  subject  to  the  requirements  of  Section  8.1.
2.4      DISSENTERS' RIGHTS.  Shareholders of Cymedix who object to the Merger
will  have  the  dissenters= rights provided in the California Act, subject to
the Company=s right to abandon the Merger under Section 8.2(a)(i) in the event
any  dissenting  shareholder  of  Cymedix  seeks  to perfect their dissenters=
rights.

     ARTICLE  III    EXCHANGE  OF  CERTIFICATES

     3.1          CONVERSION AGENT.  Prior to the Effective Date, Cymedix will
continue  to  act as conversion agent for the Cymedix Preferred Stock, and the
holders shall retain their right to convert their Cymedix Preferred Stock into
Cymedix  Common  Stock  until  the  Effective Date.  After the Effective Date,
those conversion rights will terminate, and holders of Cymedix Preferred Stock
who  have  not  timely  exercised  their conversion rights will be entitled to
receive  Merger Shares based solely on the Series A Preferred Exchange Rate or
Series  B  Preferred  Exchange  Rate,  as  applicable.

     3.2     EXCHANGE AGENT  On or before the Effective Date, the Company will
deposit  with  the  Exchange  Agent,  for  the  benefit of the shareholders of
Cymedix,  certificates  representing the Merger Shares issuable to them in the
Merger.

     3.3      EXCHANGE PROCEDURES.  (a)  After the Effective Date, each holder
of  a  certificate  that represented Cymedix Common Stock or Cymedix Preferred
Stock  prior  to  the  Effective Date (each, an Old Stock Certificate), upon
surrender of the Old Stock Certificate to the Exchange Agent, will be entitled
to  receive  in  exchange  therefor  one or more certificates representing the
number  of  Merger  Shares  that  the  holder  has the right to receive in the
Merger.

     (b)          Old  Stock  Certificates  surrendered  for exchange shall be
cancelled  upon  receipt  by  the  Exchange  Agent.    Until  surrendered  and
exchanged,  each  Old Stock Certificate shall be deemed for all purposes after
the  Effective  Date to evidence ownership of the number of Merger Shares into
which  the  shares  of  Cymedix  Common  Stock  or  Cymedix  Preferred  Stock
represented  by  the  Old  Stock Certificate have been converted under Section
2.2(b).    All  Merger  Shares  into which the Cymedix Common Stock or Cymedix
Preferred  Stock  have  been  converted  in the Merger shall be deemed for all
purposes  to  have  been  issued  by  the  Company  on  the  Effective  Date.

     (c)      If a certificate representing Merger Shares is to be issued in a
name other than the name of the registered holder of the Old Stock Certificate
surrendered  in  exchange  therefor,  it  will  be a condition to the issuance
thereof  that  the  surrendered Old Stock Certificate be properly endorsed and
that the holder requesting the exchange pay the Exchange Agent any transfer or
other taxes required by reason thereof or establish to the satisfaction of the
Exchange  Agent  that  those  taxes  have  been  paid  or  are  not  payable.

     (d)      After the Effective Date, there shall be no further registration
of  transfers  of  Cymedix Common Stock or Cymedix Preferred Stock.  Old Stock
Certificates  presented  for transfer after the Effective Date shall be deemed
to  be submitted for exchange in accordance with this Article III and transfer
in  accordance  with  the  transfer  instructions  therefor.

                  ARTICLE IV  REPRESENTATIONS AND WARRANTIES
                                  OF CYMEDIX

     Cymedix  hereby  represents  and  warrants  to  the  Company  as follows:

     4.1      ORGANIZATION AND STANDING.  Cymedix (a) was duly incorporated in
the  State of California under the name MedSoft OnLine, Inc. in November 1995,
(b)  is  validly existing and in good standing as a corporation under the laws
of  the  State  of  California, (c) has full corporate power and authority and
possesses  all  governmental franchises, licenses, permits, authorizations and
approvals  necessary  to  enable  it  to  own,  lease  or  otherwise  hold its
properties  and assets and to carry on its business as presently conducted and
(d)  is  duly  qualified  and  in  good  standing  to do business as a foreign
corporation  in  each  jurisdiction  in  which  the  conduct  or nature of its
business  or  the  ownership,  leasing or holding of its properties makes such
qualification  necessary,  except  jurisdictions  where  the  failure to be so
qualified  or  in  good  standing, individually or in the aggregate, would not
have  a  Material  Adverse Effect.  Cymedix has no Subsidiaries or Predecessor
Entities.

     4.2          AUTHORITY.    Cymedix  has all requisite corporate power and
authority  to  enter into this Agreement, to perform its obligations hereunder
and  to  consummate  the transactions contemplated hereby.  All corporate acts
and  other  proceedings  required  to  be  taken  by  Cymedix to authorize the
execution,  delivery and performance of this Agreement and the consummation of
the  transactions contemplated hereby have been duly and properly taken.  This
Agreement  has been duly executed and delivered by Cymedix and constitutes the
legal, valid and binding obligation of Cymedix, enforceable against Cymedix in
accordance  with  its  terms.

     4.3     NO CONFLICTS; CONSENTS.  Except as set forth in Schedule 4.3, the
                                                             ------------
execution  and  delivery  of  this  Agreement  by  Cymedix  does  not, and the
consummation  of  the transactions contemplated hereby and compliance with the
terms  hereof  will not conflict with or result in any violation of or default
(with  or  without  notice or lapse of time, or both) under, or give rise to a
right  of termination, cancellation, repurchase, redemption or acceleration of
any  obligation  or  to loss of a material benefit to Cymedix under, or to any
increased, additional, accelerated or guaranteed rights or entitlements of any
Person other than Cymedix under, or result in the creation of any lien, claim,
encumbrance, security interest, option, charge or restriction of any kind upon
any  of  the  properties  or  assets of Cymedix under any provision of (a) the
Certificate  of  Incorporation  or  Bylaws  of  Cymedix,  (b)  any note, bond,
mortgage,  indenture,  deed  of  trust,  license, lease, contract, commitment,
agreement  or  arrangement  to which Cymedix is a party or by which any of its
properties  or  assets  is  bound  or  (c)  any  judgment, order or decree, or
statute,  law,  ordinance,  rule  or  regulation  applicable to Cymedix or its
properties  or assets.  Except for the filing of the Certificates of Merger in
the  offices  of  the  Secretaries  of  State  of  the  States of Colorado and
California,  no consent, approval, license, permit, order or authorization of,
or  registration,  declaration  or  filing with, any Governmental Authority is
required  to  be  obtained or made by or with respect to Cymedix in connection
with  (i)  the  execution,  delivery  and performance of this Agreement or the
consummation of the transactions contemplated hereby or (ii) the operations of
the  Merger  Sub following the Effective Date as conducted on the date hereof,
other  than  filings  under  Section  13  of  the  Exchange  Act.

     4.4          BOOKS  AND RECORDS.  Cymedix has heretofore delivered to the
Company  true  and  complete  copies  of  its Certificate of Incorporation and
Bylaws,  each  as  amended  to  date,  and  minute  books, including its stock
certificate  ledger  and  stock  transfer  books.

     4.5      CAPITAL STOCK.  The authorized capital stock of Cymedix consists
of  5,000,000  shares  of  Cymedix  Common  Stock, of which 853,285 shares are
issued  and  outstanding  on  the  date  hereof, and 500,000 shares of Cymedix
Preferred  Stock,  of  which (a) 50 shares of Cymedix Series A Preferred Stock
and  138,711  shares  of  Cymedix  Series  B  Preferred  Stock  are issued and
outstanding  on  the  date  hereof  and  (b)  361,239  undesignated shares are
authorized  and  unissued  on  the date hereof.  All the outstanding shares of
capital  stock of Cymedix have been duly authorized and validly issued and are
fully  paid  and  nonassessable.    Neither  any  Cymedix Common Stock nor any
Cymedix  Preferred  Stock has been issued in violation of or is subject to any
purchase  option,  call,  right  of first refusal, preemptive, subscription or
similar  rights  under  any  provision  of  applicable law, the Certificate of
Incorporation or Bylaws of Cymedix or any contract, agreement or instrument to
which  Cymedix is subject, bound or a party or otherwise.  Except as set forth
in Schedule 4.5, there are no outstanding warrants, options, rights, phantom
   ------------
stock  rights,  agreements,  convertible  or  exchangeable securities or other
instruments  or  commitments  (i)  pursuant  to which Cymedix is or may become
obligated to issue, sell, purchase, return or redeem any shares of its capital
stock  or  other  securities or (ii) that give any Person the right to receive
any  benefits  or  rights  similar to any rights enjoyed by or accruing to the
holders  of  shares of capital stock or other interests of Cymedix.  There are
no outstanding bonds, debentures, notes or other indebtedness having the right
to  vote  on  any  matters on which shareholders of Cymedix may vote.  Cymedix
acknowledges its obligation under Section 6.2(b) to update its representations
in  this Section 4.5 and Schedule 4.5 from time to time as required to account
                         ------------
for  any  exercise  or  conversion  of  its  outstanding  securities  that are
exercisable  for  or  convertible into shares of Cymedix Common Stock prior to
the  Effective  Date.

     4.6          FINANCIAL  STATEMENTS;  UNDISCLOSED  LIABILITIES.   (a)  The
unaudited financial statements of Cymedix for the year ended December 31, 1996
and  the  six  months  ended June 30, 1997 heretofore delivered to the Company
comply  as  to  form  in  all  material  respects  with  applicable accounting
requirements,  were  prepared in accordance with generally accepted accounting
principles  applied  on a consistent basis during the periods involved (except
as  may  be  indicated  in the notes thereto) and fairly present the financial
position  of Cymedix as of the dates thereof and its results of operations for
the  periods then ended (subject, in the case of interim statements, to normal
year-end  adjustments).

     (b)      Cymedix does not have any material liabilities or obligations of
any  nature  (whether accrued, absolute, contingent, unasserted or otherwise),
except  (i)  as  disclosed, reflected or fully reserved against in its balance
sheet as of June 30, 1997 (the Cymedix Balance Sheet) and the notes thereto,
(ii)  for  items  set  forth  in  Schedule  4.6,  (iii)  for  liabilities  and
                                  -------------
obligations  incurred  in the ordinary course of business consistent with past
practice  since  the  date  of  the Balance Sheet and not in violation of this
Agreement  and  (iv)  for  Taxes.

     (c)          Except  as  set  forth  in Schedule 4.6, (i) Cymedix and any
                                             ------------
affiliated group, within the meaning of Code section 1504, of which Cymedix is
or  has  been  a  member,  has  filed or caused to be filed in a timely manner
(within  any  applicable  extension periods) all material Tax returns, reports
and  forms  required  to be filed by the Code or by applicable state, local or
foreign  tax  laws,  (ii)  all  Taxes required to be paid by Cymedix have been
timely  paid in full and all Taxes for current periods are adequately provided
for,  and  (iii) no tax liens have been filed and no material claims are being
asserted in writing with respect to any Taxes.  The federal income tax returns
filed  by  Cymedix  have  never been examined by the Internal Revenue Service.

     (d)         Except as set forth in Schedule 4.6, there are no outstanding
                                        ------------
agreements  or waivers extending the statutory period of limitation applicable
to  any material Tax returns required to be filed with respect to Cymedix, and
neither  Cymedix  nor any affiliated group, within the meaning of Code section
1504,  of which Cymedix is or has been a member has requested any extension of
time  within  which to file any material Tax return that remains unfiled as of
the  date  hereof.

     (e)      Cymedix is not a United States real property holding corporation
within  the  meaning  of  Code  section  897.

     4.7          ASSETS.  (a)  Cymedix has good and valid title to all assets
reflected  on  the  Cymedix Balance Sheet or thereafter acquired, except those
sold  or  otherwise  disposed  of for fair value since the date of the Cymedix
Balance Sheet in the ordinary course of business consistent with past practice
and  not  in  violation  of this Agreement, in each case free and clear of all
mortgages, liens, security interests or encumbrances of any kind except (i) as
set  forth  in Schedule 4.7, (ii) mechanics, materialmens, carriers, workmens,
               ------------
repairmens  or  other like liens arising or incurred in the ordinary course of
business,  liens  arising  under  original  purchase  price  conditional sales
contracts and equipment leases with third parties entered into in the ordinary
course  of  business  and liens for Taxes that are not due and payable or that
may  be  paid  without penalty, (iii) mortgages, liens, security interests and
encumbrances that secure debt  reflected as a liability on the Cymedix Balance
Sheet  and  the  existence of which is indicated in the notes thereto and (iv)
other  imperfections  of  title  or  encumbrances,  if  any,  that  do  not,
individually  or  in  the  aggregate,  materially impair the continued use and
operation  of  the  assets  to which they relate in the business of Cymedix as
presently  conducted  (the  mortgages, liens, security interests, encumbrances
and imperfections of title described in clauses (ii), (iii) and (iv) above are
hereinafter  referred  to  in  this  Article  IV  as  Permitted  Liens).

     (b)       All the material tangible personal property of Cymedix has been
maintained  in  all  material  respects  in  accordance  with  good commercial
practices.   Each item of material tangible personal property of Cymedix is in
all  material  respects  in good operating condition and repair, ordinary wear
and tear excepted.  All leased personal property of Cymedix is in all material
respects in the condition required by the terms of the applicable lease during
the  term  of  the  lease  and  upon  the  expiration  thereof.

     4.8          INTELLECTUAL  PROPERTY.   Schedule 4.8 sets forth a true and
                                            ------------
complete  list  of  (a)  all  patents  and  patent applications, including the
status,  registration  or  application  numbers  thereof,  (b)  all trademarks
(registered  or  unregistered), including a list of all jurisdictions in which
they  are  registered  or  applied  for  and  all registration and application
numbers  thereof,  (c)  all  service  marks  and  copyrights  and applications
therefor  and  (d)  all  other  material intellectual property and proprietary
rights,  whether  or  not  subject  to  statutory  registration  or protection
(collectively,  Cymedix  Intellectual  Property),  owned,  used, filed by or
licensed  to  Cymedix.   Except as set forth in Schedule 4.8, Cymedix owns and
                                                ------------
has  the  right to use, execute, reproduce, display, perform, modify, enhance,
distribute, prepare derivative works of and sublicense, without payment to any
other  person,  all Cymedix Intellectual Property, and the consummation of the
transactions  contemplated  hereby will not conflict with, alter or impair any
of  those rights.  Cymedix has not granted any options, licenses or agreements
of  any kind relating to the Cymedix Intellectual Property or the marketing or
distribution  thereof,  except  for  nonexclusive licenses to end users in the
ordinary course of business or as otherwise indicated in Schedule 4.8.  Except
                                                         ------------
as  set  forth  in  Schedule  4.8,  Cymedix  is not bound by or a party to any
                    -------------
options,  licenses  or  agreements  of  any  kind  relating  to  the  Cymedix
Intellectual  Property.    Subject to the rights of third parties set forth in
Schedule 4.8, all Cymedix Intellectual Property is free and clear of any third
  ----------
party  claims  and  all liens, security interests and encumbrances whatsoever,
other  than  Permitted  Liens.    The  conduct  of  the business of Cymedix as
presently  conducted  does  not  violate,  conflict  with  or  infringe  the
intellectual  property  rights  of  any  other Person.  Except as set forth in
Schedule  4.8,  (i)  no  claims  are  pending or, to the knowledge of Cymedix,
    ---------
threatened,  against  Cymedix  by  any  Person  with respect to the ownership,
    -
validity,  enforceability,  effectiveness  or  use of any Cymedix Intellectual
    -
Property  and  (ii)  since  its  inception,  Cymedix  has  not  received  any
communications  alleging  that  it  has  violated any rights relating thereto.

     4.9      CONTRACTS.  (a)  Except as set forth in Schedule 4.9, Cymedix is
                                                      ------------
not  a  party  to  or  bound  by  any  of  the  following:

     (i)    employment  or  consulting  agreement that has an aggregate future
liability in excess of $10,000 and is not terminable by Cymedix upon notice of
not  more  than  60  days  for  a  cost  of  less  than  $5,000;

     (ii)      employee collective bargaining agreement or other contract with
any  labor  union;

     (iii)     covenant of Cymedix not to compete or otherwise restricting the
operations  of  Cymedix;

     (iv)         agreement, contract or other arrangement with any current or
former  officer,  director  or employee of Cymedix or any Affiliate of Cymedix
other  than  employment and consulting agreements covered by clause (i) above;

     (v)          lease  or  similar agreement with any person under which (A)
Cymedix  is  lessee  of  or holds or uses any machinery, equipment, vehicle or
other tangible personal property owned by any other Person or (B) Cymedix is a
lessor  or  sublessor  of, or makes available for use by any other Person, any
tangible personal property owned or leased by Cymedix, which in any case or in
the aggregate have a total future liability or receivable, as the case may be,
in excess of $10,000 and are not terminable by Cymedix upon notice of not more
than  60  days  for  a  cost  of  less  than  $10,000;

     (vi)  (A)  continuing  contract  for  the  future  purchase of materials,
supplies  or  equipment,  (B) management, service, consulting or other similar
type  of  contract  or  (C) advertising agreement or arrangement, which in any
case  or  in  the aggregate have a total future liability in excess of $10,000
and  are  not terminable by Cymedix upon notice of not more than 60 days for a
cost  of  less  than  $10,000;

     (vii)       material license, option or other agreement relating in whole
or  in part to (A) the Cymedix Intellectual Property, including any license or
other  agreement  under  which Cymedix is licensee or licensor thereof, or (B)
trade  secrets,  confidential  information  or  other  proprietary  rights and
processes  of  Cymedix;

     (viii)  agreement,  contract  or other instrument under which Cymedix has
borrowed any money from, or issued any note, bond, debenture or other evidence
of  indebtedness to, any other Person that in any individual case is in excess
of  $5,000;

     (ix)          agreement, contract or other instrument under which (A) any
Person  has  directly  or  indirectly  guaranteed indebtedness, liabilities or
obligations  of  Cymedix  or (B) Cymedix has directly or indirectly guaranteed
indebtedness,  liabilities  or  obligations  of  any  other Person that in any
individual  case  is  in  excess  of  $5,000;

     (x)      agreement, contract or other instrument under which Cymedix has,
directly or indirectly, made any advance, loan, extension of credit or capital
contribution  to,  or  other  investment  in,  any  other  Person  that in any
individual  case  is  in  excess  of  $5,000;

     (xi)          agreement,  contract  or  other  instrument  providing  for
indemnification  of  any  Person  with  respect to liabilities relating to any
current  or  former  business  of  Cymedix;  or

     (xii)      other agreement, contract or other instrument to which Cymedix
is  a  party or by or to which it or any of its assets or business is bound or
subject  that  has an aggregate future liability to any other Person in excess
of  $10,000  and  is not terminable by Cymedix upon notice of not more than 60
days  for  a  cost  of  less  than  $10,000.

     (b)     Except as set forth in Schedule 4.9, all agreements, contracts or
                                    ------------
other  instruments of Cymedix listed or required to be listed in the Schedules
hereto  (collectively, the Cymedix Contracts) are valid, binding and in full
force  and effect and are enforceable by Cymedix in accordance with its terms.
Except  as  set  forth  in  Schedule  4.9,  Cymedix has performed all material
                            -------------
obligations required to be performed by it to date under the Cymedix Contracts
and it is not in breach or default in any material respect thereunder (with or
without  the lapse of time or the giving of notice, or both) nor has any other
party  to any of the Cymedix Contracts notified Cymedix of that party=s belief
that  Cymedix  is  or is likely to become in breach or default in any material
respect  thereunder  or of that party=s intention to accelerate or modify in a
manner  adverse to Cymedix any of its obligations or rights thereunder and, to
the knowledge of Cymedix, no other party to any of the Cymedix Contracts is in
breach  or  default  in  any  material respect thereunder (with or without the
lapse  of  time  or  the  giving  of  notice,  or  both).

     4.10    LITIGATION.    Schedule  4.10  sets  forth  a list of all pending
                            --------------
lawsuits  or  claims  against  or  affecting Cymedix or any of its properties,
assets,  operations  or  business and which (a) relate to or involve more than
$5,000,  (b)  seek  any  material  injunctive  relief  or  (c)  relate  to the
transactions  contemplated by this Agreement.  Except as set forth in Schedule
                                                                      --------
4.10,  (i)  none of the lawsuits or claims listed therein as to which there is
- ----
at  least  a reasonable possibility of adverse determination could have, if so
determined,  individually or in the aggregate, a Material Adverse Effect, (ii)
Cymedix  is not a party or subject to or in default under any judgment, order,
injunction  or  decree  of  any Governmental Authority or arbitration tribunal
applicable  to  it  or  any of its properties, assets, operations or business,
(iii)  there  is  no  lawsuit  or  claim  by Cymedix pending, or which Cymedix
intends  to  initiate,  against  any other Person and (iv) to the knowledge of
Cymedix,  there  is  no  pending  or  threatened investigation of or affecting
Cymedix  by  any  Governmental  Authority.

     4.11    INSURANCE.    Cymedix  maintains  policies  of fire and casualty,
liability  and  other  forms  of  insurance  in  amounts, with deductibles and
against  risks  and  losses  that  are,  in  its  judgment, reasonable for the
business  and  assets  of  Cymedix.    The  insurance policies maintained with
respect  to Cymedix and its assets and properties are listed in Schedule 4.11.
                                                                -------------
Except  as set forth in  Schedule 4.11, all of the policies listed therein are
                         -------------
in  full force and effect, all premiums due and payable thereon have been paid
(other than retroactive or retrospective premium adjustments that are not yet,
but may be, required to be paid with respect to any period ending prior to the
Effective  Date  under  comprehensive  general  liability  and  workmen=s
compensation insurance policies), and no notice of cancellation or termination
has  been  received  with  respect  thereto.  To the knowledge of Cymedix, its
activities  and  operations  have been conducted in a manner conforming in all
material  respects  to  all  applicable  provisions of its insurance policies.
4.12    BENEFIT  PLANS.    (a)    Schedule  4.12  sets  forth a list and brief
                                  --------------
description  of  all Benefit Plans maintained or contributed to by Cymedix for
the benefit of any of its officers or other employees.  Cymedix has heretofore
delivered to the Company true, complete and correct copies of (i) each Benefit
Plan,  (ii) the most recent annual report on Form 5500 filed with the Internal
Revenue  Service  with  respect  to each Benefit Plan (if required), (iii) the
most recent summary plan description for each Benefit Plan for which a summary
plan  description  is  required  and  (iv) each trust agreement, group annuity
contract  and  other financing and funding arrangement relating to any Benefit
Plan.

     (b)         Each Benefit Plan maintained or contributed to by Cymedix has
been  administered  in  all  material  respects  in accordance with its terms.
Cymedix  and  all  of  its  Benefit  Plans  are  in compliance in all material
respects  with  the applicable provisions of ERISA and the Code.  All material
reports,  returns  and  similar  documents  with  respect to the Benefit Plans
required  to  be  filed  with any Governmental Authority or distributed to any
Benefit  Plan  participant  have  been  duly  and timely filed or distributed.
There  are  no lawsuits, actions, termination proceedings or other proceedings
pending  or,  to the knowledge of Cymedix, threatened against or involving any
of  its  Benefit  Plans  and,  to  the  knowledge  of  Cymedix,  there  are no
investigations  by  any  Governmental Authority or other claims (except claims
for  benefits payable in the normal operation of the Benefit Plans) pending or
threatened  against  or  involving  any  of its Benefit Plans or asserting any
rights  to  benefits  under  any  Benefit  Plan  that  individually  or in the
aggregate  would have a Material Adverse Effect.  To the knowledge of Cymedix,
there  are  no  unasserted claims pending or threatened that if asserted would
have  at  least  a  reasonable  possibility  of  an  adverse  determination.

     (c)     With respect to all Benefit Plans maintained or contributed to by
Cymedix, (i) all contributions to and payments from the Benefit Plans required
thereby  or  by  ERISA  section 302 or Code section 412 have been timely made,
(ii)  there  has  been  no  application  for  or waiver of the minimum funding
standards  imposed  by  Code  section  412  and  (iii)  no Pension Plan has an
Aaccumulated  funding deficiency@ within the meaning of Code section 412(a) as
of  the  most  recent  plan  year.

     (d)       No prohibited transaction, as defined in Code section 4975 or
ERISA  section  406, has occurred that involves the assets of any Benefit Plan
and  that  could subject Cymedix or any of its  employees or, to the knowledge
of  Cymedix, a trustee, administrator or other fiduciary of any trusts created
under  any  of  its  Benefit  Plans  to  the  tax  or  penalty  on  prohibited
transactions  imposed  by  ERISA  section  4975 or the sanctions imposed under
Title  I of ERISA.  No Pension Plan maintained by Cymedix has been terminated,
nor  has  there  been any reportable event, as defined in ERISA section 4043
and the regulations thereunder, with respect thereto.  Neither Cymedix nor any
trustee,  administrator or other fiduciary of any of its Benefit Plans nor any
agent  of  any  of  the  foregoing  has engaged in any transaction or acted or
failed  to  act  in  a  manner that could subject Cymedix to any liability for
breach  of  fiduciary  duty  under  ERISA  or  any  other  applicable  law.

     (e)       At no time since its inception has Cymedix (i) been required to
contribute  to  any  Amultiemployer  plan,@  as  defined  in  ERISA  section
4001(a)(3),  for  the  benefit  of  any  of its officers or other employees of
Cymedix,  (ii)  incurred any withdrawal liability, within the meaning of ERISA
section 4201, with respect to any that multiemployer plan, which liability has
not  been fully paid as of the date hereof, or (iii) announced an intention to
withdraw, but not yet completed such withdrawal, from that multiemployer plan.
If  Cymedix  were  to  make a complete withdrawal from any multiemployer plan,
within  the  meaning of ERISA section 4203, the withdrawal liability would not
exceed  $10,000  in  the  aggregate.
(f)          With  respect  to any Benefit Plan of Cymedix that is an employee
welfare  benefit  plan,  except  as  disclosed in Schedule 4.12, (i) it is not
                                                  -------------
unfunded or funded through a welfare benefits fund, as defined in Code section
419(e),  (ii)  it organized as a group health plan, as defined in Code section
5000(b)(1),  it  complies  in  all  material  respects  with  the  applicable
requirements  of  Code  section  4980B(f)  and  (iii)  it  may  be  amended or
terminated  without  material  liability  to  Cymedix.

     (g)          Cymedix  has no current or projected liability or contingent
obligation  in  respect of medical or other benefits for its retired or former
employees.

     (h)    Except  as  set  forth in Schedule 4.12, (i) no employee or former
                                      -------------
employee  of Cymedix will become entitled to any bonus, retirement, severance,
job  security or similar benefit or any enhanced benefit solely as a result of
the  transactions  contemplated hereby, alone or in conjunction with any other
events  or  occurrences,  and (ii) no amount payable to any employee under any
Benefit  Plan  or  other  arrangement of Cymedix will fail to be deductible by
reason  of  Code  section  280G.

     (i)       Cymedix has not (i) engaged in a transaction described in ERISA
section  4069  that  could  subject it to liability at any time after the date
hereof  or  (ii)  engaged  in  any act or omission that could result in fines,
penalties,  taxes  or  related  charges  under  ERISA.

     (j)      No compensation payable by Cymedix to any of its employees under
any  existing  contract,  Benefit  Plan  or  other  employment  arrangement or
understanding  (including  by  reason of the transactions contemplated hereby)
would  be  subject  to  disallowance  under  Code  section  162(m).

     4.13    ABSENCE  OF  CHANGES  OR EVENTS.  Except as set forth in Schedule
                                                                      --------
4.13,  (i) since the date of the Cymedix Balance Sheet, there has not occurred
any  event  or events or arisen any change of affairs that, individually or in
the aggregate, has had or could have a Material Adverse Effect, (ii) since the
date  of the Cymedix Balance Sheet, the business of Cymedix has been conducted
in  the  ordinary  course  and  in substantially the same manner as previously
conducted,  (iii) Cymedix has made all reasonable efforts consistent with past
practices  to adhere to the Cymedix Budget and preserve its relationships with
customers,  suppliers and others with whom it deals, and (iv) from the date of
the  Cymedix  Balance  Sheet,  Cymedix has not taken any action that, if taken
after  the  date  of  this  Agreement, would constitute a breach of any of its
covenants  set  forth  herein.

     4.14    COMPLIANCE  WITH  APPLICABLE  LAWS.   (a)  Except as set forth on
Schedule  4.14,  Cymedix  is  in  compliance in all material respects with all
     ---------
applicable  statutes,  laws,  ordinances, rules, orders and regulations of any
Governmental  Authority  applicable  to its business and operations, including
those relating to occupational health and safety (for purposes of this Section
4.14,  Applicable  Laws).  Except as set forth in Schedule 4.14, Cymedix has
                                                    -------------
not  received  any  communication  since  its  inception  from  a Governmental
Authority  that alleges its failure to comply in any material respect with any
Applicable  Laws.

     (b)       Cymedix has provided the Company with all environmental reports
relating  to  the  facilities and operations of Cymedix identified in Schedule
                                                                      --------
4.14  (for  purposes  of this Section 4.14, Environmental Reports).  Cymedix
  --
has  not  received  any  oral  or  written  communication  from a Governmental
Authority  that  alleges  its failure to comply with any Environmental Laws in
any  manner  that  has  not  been  finally  resolved.  Cymedix holds and is in
compliance with all permits, licenses and governmental authorizations required
to  conduct  its  business  under  Environmental Laws.  Except as set forth in
Schedule 4.14, Cymedix is in compliance with all Environmental Laws and is not
    ---------
subject  to  any  judgment,  decree  or  order relating to compliance with any
Environmental  Law or to investigation or cleanup of Hazardous Materials under
any  Environmental  Law.   Cymedix has no contingent liabilities in respect of
its  business in connection with any Hazardous Materials that, individually or
in  the  aggregate, would have a Material Adverse Effect.  Except as set forth
in Schedule 4.14, there are no aboveground or underground storage tanks on any
   -------------
property of Cymedix, and all former underground storage tanks have been closed
or  removed  in  accordance  with  all  Environmental  Laws.

     4.15   EMPLOYEE AND LABOR MATTERS.  Except as set forth in Schedule 4.15,
                                                                -------------
(a)  there  is,  and  since  the inception of Cymedix there has been, no labor
strike,  dispute,  work  stoppage  or  lockout  pending  or, to its knowledge,
threatened  against  or  affecting  Cymedix,  (b)  to  its knowledge, no union
organizational  campaign  is  in  progress  with  respect  to the employees of
Cymedix and no question exists concerning representation of its employees, (c)
Cymedix  is  not  engaged in any unfair labor practice, (d) there is no unfair
labor  practice  charge  or complaint pending or, to its knowledge, threatened
against  Cymedix  before  the National Labor Relations Board, (e) there are no
pending or, to its knowledge, threatened union grievances against Cymedix that
would have a Material Adverse Effect if determined against Cymedix,  (f) there
are no pending or, to its knowledge, threatened charges against Cymedix or any
current  or former employee of Cymedix before the Equal Employment Opportunity
Commission  or  any  state  or  local agency responsible for the prevention of
unlawful  employment  practices and (g) Cymedix has not received notice during
the past two years of the intent of any Governmental Authority responsible for
the  enforcement of labor or employment laws to conduct an investigation of or
affecting Cymedix and, to its knowledge, no such investigation is in progress.

     4.16    LICENSES;  PERMITS.   Cymedix has obtained all material licenses,
permits and authorizations from Governmental Authorities that are necessary or
desirable  for  the  conduct of its business.  Except as set forth in Schedule
                                                                      --------
4.16,  (a)  all required licenses, permits and authorizations are validly held
  --
by  Cymedix,  (b) Cymedix has complied in all material respects with all terms
and  conditions  thereof  and  (c) the same will not be subject to suspension,
modification,  revocation  or  nonrenewal  as  a  result  of the execution and
delivery  of  this  Agreement  or  the  consummation  of  the  transactions
contemplated  hereby.

     4.17   DISCLOSURE.  No representation or warranty of Cymedix contained in
this  Agreement,  no  statement  contained  in  any  document,  certificate or
Schedule  and  no  data  provided  in  connection  with  the  due  diligence
investigation  contemplated by Section 6(a) furnished or to be furnished by or
on  behalf of Cymedix to the Company or any of its representatives pursuant to
this  Agreement  contains  or  will contain any untrue statement of a material
fact  or  omits or will omit to state any material fact necessary, in light of
the  circumstances  under  which  it was or will be made, in order to make the
statements  herein  or therein not misleading or necessary to fully and fairly
provide  the  information  required  to  be  provided  therein.  The financial
projections  and  other  information relating to Cymedix in the Cymedix Budget
delivered  to  the  Company  were prepared on the basis of assumptions Cymedix
reasonably believed in good faith at the time of preparation to be reasonable,
and  Cymedix has no knowledge of any fact or information that would lead it to
believe  that  those  assumptions  are incorrect or misleading in any material
respect.

     ARTICLE  V    REPRESENTATIONS  AND  WARRANTIES  OF
     THE  COMPANY

     The  Company  hereby  represents  and  warrants  to  Cymedix  as follows:

     5.1          ORGANIZATION  AND  STANDING.    Each  of the Company and its
Subsidiaries is a corporation, limited partnership or general partnership duly
organized  or  formed, validly existing and in good standing under the laws of
its  jurisdiction  of  incorporation,  organization  or  formation,  which
jurisdiction  is  set  forth  in  Schedule  5.1.   Each of the Company and its
                                  -------------
Subsidiaries  has  full  corporate  or  partnership  power  and  authority and
possesses  all  governmental franchises, licenses, permits, authorizations and
approvals  necessary  to  enable  it  to  own,  lease  or  otherwise  hold its
properties  and  assets  and  to carry on its business as presently conducted.
Each  of  the  Company  and  its  Subsidiaries  is  duly qualified and in good
standing  to  do  business  as  a  foreign  corporation  or limited or general
partnership  in  each  jurisdiction  in  which  the  conduct  or nature of its
business  or  the  ownership,  leasing or holding of its properties makes that
qualification  necessary,  except  jurisdictions  where  the  failure to be so
qualified  or  in  good  standing, individually or in the aggregate, would not
have  a Material Adverse Effect.  A list of the Company=s Subsidiaries, and of
the  jurisdictions  in which the Company and the Subsidiaries are so qualified
is  set  forth  in  Schedule  5.1.
                    -------------

     5.2        AUTHORITY.  (a)  The Company has all requisite corporate power
and  authority  to  enter  into  this  Agreement,  to  perform its obligations
hereunder  and  to  consummate  the  transactions  contemplated  hereby.   All
corporate  acts  and  other proceedings required to be taken by the Company to
authorize  the  execution,  delivery and performance of this Agreement and the
consummation  of  the  transactions  contemplated  hereby  have  been duly and
properly  taken.    This Agreement has been duly executed and delivered by the
Company  and  constitutes  the  legal,  valid  and  binding  obligation of the
Company,  enforceable  against  the  Company  in  accordance  with  its terms.

     (b)          The Merger Shares have been duly authorized by all requisite
corporate  action  of the Company and shall, upon issuance, be validly issued,
fully paid and nonassessable.  Upon delivery to the shareholders of Cymedix of
certificates  representing  the  Merger Shares in exchange for their Old Stock
Certificates,  they  will acquire good and valid title to their Merger Shares,
free  and  clear  of  any  liens,  claims,  encumbrances,  security interests,
options,  charges  and restrictions of any kind, other than those arising from
their own acts or omissions.  Other than this Agreement, the Merger Shares are
not  subject  to  any  agreement,  arrangement,  commitment  or understanding,
including  any  restriction    relating  to  the  voting,  dividend  rights or
disposition  of the Merger Shares.  No stock transfer taxes will be due in the
State  of  Colorado  as  a  result  of  the  issuance  of  the  Merger Shares.

     (c)       The Company has reserved or shall reserve by the Effective Date
and  shall keep reserved for issuance and delivery, out of  its authorized and
unissued  shares  of Company Common Stock, all Reserved Merger Shares issuable
from  time  to  time  upon  exercise  of  Cymedix Stock Options assumed in the
Merger,  free and clear of any and all liens.  Upon delivery to option holders
of  certificates  representing  the  Reserved Merger Shares, they will acquire
good  and  valid  title to their Reserved Merger Shares, free and clear of any
liens,  claims,  encumbrances,  security  interests,  options,  charges  and
restrictions  of  any kind, other than those arising from their own acts.  The
Reserved  Merger  Shares  are  not  subject  to  any  agreement,  arrangement,
commitment  or  understanding restricting or otherwise relating to the voting,
dividend  rights or disposition of the Reserved Merger Shares, other than this
Agreement,  the  Cymedix  Option  Plans  and the outstanding option agreements
thereunder.  No stock transfer taxes will be due in the State of Colorado as a
result  of  the  issuance  of  the  Reserved  Merger  Shares.

     (d)       The Company Board has taken or shall take by the Effective Date
all  action necessary to approve the issuance of the Merger Shares pursuant to
the  Merger.    No  anti-takeover  or similar statute or regulation applies or
purports  to  apply  to  the  transactions  contemplated  by  this  Agreement.

     5.3     NO CONFLICTS; CONSENTS.  Except as set forth in Schedule 5.3, the
                                                             ------------
execution  and  delivery  of  this  Agreement by the Company does not, and the
consummation  of  the transactions contemplated hereby and compliance with the
terms  hereof  will not conflict with or result in any violation of or default
(with  or  without  notice or lapse of time, or both) under, or give rise to a
right  of termination, cancellation, repurchase, redemption or acceleration of
any  obligation  or  to loss of a material benefit to the Company under, or to
any increased, additional, accelerated or guaranteed rights or entitlements of
any  person  other  than  the  Company under, or result in the creation of any
lien,  claim, encumbrance, security interest, option, charge or restriction of
any  kind  upon  any  of  the  properties  or  assets of the Company under any
provision  of  (a)  the Certificate of Incorporation or Bylaws of the Company,
(b)  any  note,  bond,  mortgage,  indenture,  deed  of trust, license, lease,
contract, commitment, agreement or arrangement to which the Company is a party
or  by  which  any  of  its properties or assets is bound or (c) any judgment,
order  or decree, or statute, law, ordinance, rule or regulation applicable to
the  Company  or  its  properties  or  assets.    Except for the filing of the
Certificates  of  Merger  in  the  offices  of the Secretaries of State of the
States  of  Colorado  and  California,  no consent, approval, license, permit,
order  or  authorization  of, or registration, declaration or filing with, any
Governmental  Authority  is required to be obtained or made by or with respect
to  the Company in connection with (i) the execution, delivery and performance
of  this Agreement or the consummation of the transactions contemplated hereby
or  (ii)  the  operations  of  the  Company    following the Effective Date as
conducted  on  the  date  hereof,  other  than filings under Section 13 of the
Exchange  Act.

     5.4          BOOKS  AND RECORDS.  The Company has heretofore delivered to
Cymedix  true  and  complete  copies  of  its Certificate of Incorporation and
Bylaws,  each  as amended to date, and minute books covering all periods since
January  1,  1995.

     5.5          CAPITAL  STOCK.  The authorized capital stock of the Company
consists of (a) 25,000,000 shares of Company Common Stock, of which 12,256,272
shares  are    issued  and  outstanding on the date hereof,  (b) 488 shares of
Company  Preferred  Stock  designated  as 1996 Convertible Preferred Stock, of
which  27.5  shares are issued and outstanding on the date hereof, and (c) 300
shares  of  Company  Preferred  Stock designated as 1997 Convertible Preferred
Stock,  of  which  108.9 shares are issued and outstanding on the date hereof.
All  the  outstanding  shares  of  capital stock of the Company have been duly
authorized  and  validly issued and are fully paid and nonassessable.  Neither
any of the Company Common Stock nor Company Preferred Stock has been issued in
violation  of  or  is  subject  to  any  purchase option, call, right of first
refusal,  preemptive,  subscription  or  similar rights under any provision of
applicable  law,  the Certificate of Incorporation or Bylaws of the Company or
any  contract,  agreement or instrument to which the Company is subject, bound
or  a  party  or otherwise.  Except as set forth in Schedule 5.5, there are no
                                                    ------------
outstanding  warrants,  options,  rights,  Aphantom@ stock rights, agreements,
convertible or exchangeable securities or other instruments or commitments (i)
pursuant  to  which  the  Company  is  or may become obligated to issue, sell,
purchase, return or redeem any shares of its capital stock or other securities
or  (ii)  that  give  any  Person  the right to receive any benefits or rights
similar  to  any  rights  enjoyed  by  or accruing to the holders of shares of
capital  stock  or  other  interests of the Company.  There are no outstanding
bonds, debentures, notes or other indebtedness having the right to vote on any
matters  on  which  shareholders  of    the  Company  may  vote.   The Company
acknowledges  its  obligation under Section 6.2(b) to update Schedule 5.5 from
                                                             ------------
time  to  time  as  required  to account for any exercise or conversion of its
outstanding  securities  that  are  convertible  or  exercisable for shares of
Company  Common  Stock  prior  to  the  Effective  Date.

     5.6      FINANCIAL STATEMENTS; UNDISCLOSED LIABILITIES.  (a)  The Company
and  any  Predecessor Entity has filed all required reports, schedules, forms,
statements  and other documents with the SEC since December 31, 1992 (the SEC
Documents).   As of their respective dates, the SEC Documents complied in all
material  respects with the requirements of the Securities Act or the Exchange
Act,  as  the  case  may be, applicable thereto, and none of the SEC Documents
contained  any  untrue  statement  of  a  material  fact or omitted to state a
material  fact required to be stated therein or necessary in order to make the
statements  therein, in light of the circumstances under which they were made,
not  misleading.  The financial statements of the Company and each Predecessor
Entity  included  in  the  SEC  Documents  comply  as  to form in all material
respects  with  applicable accounting requirements and the published rules and
regulations  of the SEC with respect thereto, were prepared in accordance with
generally  accepted  accounting  principles  (except, in the case of unaudited
statements, as permitted for use on Form 10-QSB) applied on a consistent basis
during  the periods involved (except as may be indicated in the notes thereto)
and  fairly present the consolidated financial position of the Company and its
Subsidiaries  and of each Predecessor Entity and its Subsidiaries, as the case
may  be, as of the dates thereof and the consolidated results of operations of
the  Company  and  the  Subsidiaries  and  of  each Predecessor Entity and its
subsidiaries,  as the case may be, for the periods then ended (subject, in the
case  of  any  unaudited  statements,  to  normal  year-end  adjustments).

     (b)          The  Company  and  its Subsidiaries do not have any material
liabilities  or  obligations  of  any  nature  (whether  accrued,  absolute,
contingent,  unasserted  or  otherwise), except (i) as disclosed, reflected or
fully  reserved  against  in  the Company Balance Sheet and the notes thereto,
(ii)  for  items  set  forth  in  Schedule  5.6,  (iii)  for  liabilities  and
                                  -------------
obligations  incurred  in the ordinary course of business consistent with past
practice  since  the  date  of  the  Company Balance Sheet and (iv) for Taxes.

     (c)          Except as set forth in Schedule 5.6, (i) the Company and any
                                         ------------
affiliated  group,  within  the  meaning  of  Code  section 1504, of which the
Company  is  or has been a member, has filed or caused to be filed in a timely
manner  (within  any  applicable  extension periods) all material Tax returns,
reports  and  forms  required  to be filed by the Code or by applicable state,
local  or  foreign tax laws, (ii) all Taxes required to be paid by the Company
have been timely paid in full and all Taxes for current periods are adequately
provided  for,  and  (iii) no tax liens have been filed and no material claims
are  being asserted in writing with respect to any Taxes.  Except as set forth
in  Schedule  5.6,  the  federal  income tax returns filed by the Company have
    -------------
never  been  examined  by  the  Internal  Revenue  Service.
   -

     (d)         Except as set forth in Schedule 5.6, there are no outstanding
                                        ------------
agreements  or waivers extending the statutory period of limitation applicable
to  any material Tax returns required to be filed with respect to the Company,
and  neither  the Company nor any affiliated group, within the meaning of Code
section  1504,  of which the Company is or has been a member has requested any
extension  of  time  within which to file any material Tax return that remains
unfiled  as  of  the  date  hereof.

     (e)          The  Company  is  not  a United States real property holding
corporation  within  the  meaning  of  Code  section  897.

     5.7      ASSETS.  (a)  The Company has good and valid title to all assets
reflected  on  the  Company Balance Sheet or thereafter acquired, except those
sold  or  otherwise  disposed  of for fair value since the date of the Company
Balance  Sheet  in  the  ordinary  course  of  business  consistent  with past
practice,  in  each  case  free  and  clear  of all mortgages, liens, security
interests or encumbrances of any kind except (i) as set forth in Schedule 5.7,
                                                                 ------------
(ii)  mechanics,  materialmens,  carriers,  workmens, repairmens or other like
liens  arising  or  incurred in the ordinary course of business, liens arising
under original purchase price conditional sales contracts and equipment leases
with  third  parties entered into in the ordinary course of business and liens
for  Taxes  that  are not due and payable or that may be paid without penalty,
(iii)  mortgages,  liens, security interests and encumbrances that secure debt
reflected  as  a  liability  on the Company Balance Sheet and the existence of
which  is indicated in the notes thereto and (iv) other imperfections of title
or  encumbrances,  if  any,  that  do  not,  individually or in the aggregate,
materially  impair the continued use and operation of the assets to which they
relate  in  the business of the Company as presently conducted (the mortgages,
liens,  security  interests, encumbrances and imperfections of title described
in  clauses  (ii),  (iii)  and  (iv) above are hereinafter referred to in this
Article  V  as  Permitted  Liens).

     (b)        All the material tangible personal property of the Company has
been  maintained  in  all material respects in accordance with good commercial
practices.  Each item of material tangible personal property of the Company is
in all material respects in good operating condition and repair, ordinary wear
and  tear  excepted.    All  leased personal property of the Company is in all
material  respects  in  the  condition required by the terms of the applicable
lease  during  the  term  of  the  lease  and  upon  the  expiration  thereof.

     5.8          INTELLECTUAL  PROPERTY.   Schedule 5.8 sets forth a true and
                                            ------------
complete  list  of  (a)  all  patents  and  patent applications, including the
status,  registration  or  application  numbers  thereof,  (b)  all trademarks
(registered  or  unregistered), including a list of all jurisdictions in which
they  are  registered  or  applied  for  and  all registration and application
numbers  thereof,  (c)  all  service  marks  and  copyrights  and applications
therefor  and  (d)  all  other  material intellectual property and proprietary
rights,  whether  or  not  subject  to  statutory  registration  or protection
(collectively,  Company  Intellectual  Property),  owned,  used, filed by or
licensed  to  the  Company.   Except as set forth in Schedule 5.8, the Company
                                                     ------------
owns  and  has the right to use, execute, reproduce, display, perform, modify,
enhance,  distribute,  prepare  derivative  works  of  and sublicense, without
payment  to  any  other  person,  all  Company  Intellectual Property, and the
consummation  of  the transactions contemplated hereby will not conflict with,
alter or impair any of those rights.  The Company has not granted any options,
licenses  or  agreements  of  any  kind  relating  to the Company Intellectual
Property  or  the  marketing  or distribution thereof, except for nonexclusive
licenses  to  end  users  in  the  ordinary course of business or as otherwise
indicated  in  Schedule 5.8.  Except as set forth in Schedule 5.8, the Company
               ------------                          ------------
is  not bound by or a party to any options, licenses or agreements of any kind
relating to the Company Intellectual Property.  Subject to the rights of third
parties  set  forth in Schedule 5.8, all Company Intellectual Property is free
                       ------------
and  clear  of  any  third  party claims and all liens, security interests and
encumbrances  whatsoever,  other  than  Permitted  Liens.   The conduct of the
business of the Company as presently conducted does not violate, conflict with
or  infringe  the intellectual property rights of any other Person.  Except as
set  forth  in Schedule 5.8, (i) no claims are pending or, to the knowledge of
               ------------
the Company, threatened, against the Company by any Person with respect to the
ownership,  validity,  enforceability,  effectiveness  or  use  of any Company
Intellectual Property and (ii) during the last five years, the Company has not
received  any communications alleging that it has violated any rights relating
thereto.

     5.9     CONTRACTS.  (a)  Except as set forth in Schedule 5.9, the Company
                                                     ------------
is  not  a  party  to  or  bound  by  any  of  the  following:

     (i)       employment or consulting agreement that has an aggregate future
liability  in  excess  of  $100,000  and is not terminable by the Company upon
notice  of  not  more  than  60  days  for  a  cost  of  less  than  $100,000;

     (ii)      employee collective bargaining agreement or other contract with
any  labor  union;

     (iii)     covenant of the Company not to compete or otherwise restricting
the  operations  of  the  Company;

     (iv)         agreement, contract or other arrangement with any current or
former  officer,  director  or employee of the Company or any Affiliate of the
Company  other  than  employment  agreements  covered  by  clause  (i)  above;

     (v)        lease or similar agreement with any person under which (A) the
Company  is  lessee  of  or holds or uses any machinery, equipment, vehicle or
other  tangible personal property owned by any other Person or (B) the Company
is  a  lessor or sublessor of, or makes available for use by any other Person,
any  tangible  personal  property owned or leased by the Company, which in any
case  or  in the aggregate have a total future liability or receivable, as the
case  may be, in excess of $100,000 and are not terminable by the Company upon
notice  of  not  more  than  60  days  for  a  cost  of  less  than  $100,000;

     (vi)  (A)  continuing  contract  for  the  future  purchase of materials,
supplies  or  equipment,  (B) management, service, consulting or other similar
type  of  contract  or  (C) advertising agreement or arrangement, which in any
case  or  in the aggregate have a total future liability in excess of $100,000
and are not terminable by the Company upon notice of not more than 60 days for
a  cost  of  less  than  $100,000;

     (vii)       material license, option or other agreement relating in whole
or  in part to (A) the Company Intellectual Property, including any license or
other  agreement  under  which the Company is licensee or licensor thereof, or
(B)  trade  secrets,  confidential information or other proprietary rights and
processes  of  the  Company;

     (viii)  agreement,  contract  or other instrument under which the Company
has  borrowed  any  money  from,  or issued any note, bond, debenture or other
evidence of indebtedness to any other Person that in any individual case is in
excess  of  $50,000;

     (ix)          agreement, contract or other instrument under which (A) any
Person  has  directly  or  indirectly  guaranteed indebtedness, liabilities or
obligations  of  the  Company  or  (B)  the Company has directly or indirectly
guaranteed  indebtedness,  liabilities or obligations of any other Person that
in  any  individual  case  is  in  excess  of  $50,000;

     (x)       agreement, contract or other instrument under which the Company
has,  directly  or  indirectly, made any advance, loan, extension of credit or
capital  contribution to, or other investment in, any other Person that in any
individual  case  is  in  excess  of  $50,000;


<PAGE>
     (xi)          agreement,  contract  or  other  instrument  providing  for
indemnification  of  any  Person  with  respect to liabilities relating to any
current  or  former  business  of  the  Company;  or

     (xii)          other agreement, contract or other instrument to which the
Company  is  a  party or by or to which it or any of its assets or business is
bound or subject that has an aggregate future liability to any other Person in
excess  of  $100,000  and  is not terminable by the Company upon notice of not
more  than  60  days  for  a  cost  of  less  than  $100,000.

     (b)     Except as set forth in Schedule 5.9, all agreements, contracts or
                                    ------------
other  instruments  of  the  Company  listed  or  required to be listed in the
Schedules  hereto  (collectively,  the Company Contracts) are valid, binding
and  in full force and effect and are enforceable by the Company in accordance
with  its  terms.    Except  as  set  forth  in  Schedule 5.9, the Company has
                                                 ------------
performed  all  material  obligations  required  to be performed by it to date
under the Company Contracts and it is not in breach or default in any material
respect thereunder (with or without the lapse of time or the giving of notice,
or  both) nor has any other party to any of the Company Contracts notified the
Company  of  that  party=s  belief  that the Company or is likely to become in
breach  or  default  in  any  material  respect  thereunder or of that party=s
intention  to  accelerate  or modify in a manner adverse to the Company any of
its  obligations or rights thereunder and, to the knowledge of the Company, no
other  party  to  any  of the Company Contracts is in breach or default in any
material  respect  thereunder (with or without the lapse of time or the giving
of  notice,  or  both).

     5.10    LITIGATION.    Schedule  5.10  sets  forth  a list of all pending
                            --------------
lawsuits  or claims against or affecting the Company or any of its properties,
assets,  operations  or  business and which (a) relate to or involve more than
$50,000,  (b)  seek  any  material  injunctive  relief  or  (c)  relate to the
transactions  contemplated by this Agreement.  Except as set forth in Schedule
                                                                      --------
5.10,  none  of  the lawsuits or claims listed therein as to which there is at
- ----
least  a  reasonable  possibility  of  adverse determination could have, if so
- --
determined,  individually  or  in  the  aggregate,  a Material Adverse Effect.
- --
Except  as  set  forth  in  Schedule  5.10,  (i) the Company is not a party or
- --
subject  to  or  in default under any judgment, order, injunction or decree of
- --
any  Governmental Authority or arbitration tribunal applicable to it or any of
- --
its  properties,  assets,  operations or business, (ii) there is no lawsuit or
claim  by  the  Company  pending,  or  which  the Company intends to initiate,
against  any other Person, and (iii) to the knowledge of the Company, there is
no  pending  or  threatened  investigation  of or affecting the Company by any
Governmental  Authority.

     5.11    INSURANCE.   The Company maintains policies of fire and casualty,
liability  and  other  forms  of  insurance  in  amounts, with deductibles and
against  risks  and  losses  that  are,  in  its  judgment, reasonable for the
business  and  assets  of the Company.  The insurance policies maintained with
respect  to  the  Company and its assets and properties are listed in Schedule
                                                                      --------
5.11.    Except  as  set  forth  in  Schedule 5.11, all of the policies listed
  --                                 -------------
therein  are  in  full  force and effect, all premiums due and payable thereon
  --
have  been  paid  (other than retroactive or retrospective premium adjustments
  -
that  are  not yet, but may be, required to be paid with respect to any period
ending  prior  to the Effective Date under comprehensive general liability and
workmen=s  compensation  insurance policies), and no notice of cancellation or
termination  has  been received with respect thereto.  To the knowledge of the
Company,  its  activities  and  operations  have  been  conducted  in a manner
conforming  in  all  material  respects  to  all  applicable provisions of its
insurance  policies.

     5.12    BENEFIT  PLANS.    (a)  Schedule 5.12 sets forth a list and brief
                                     -------------
description  of  all Benefit Plans maintained or contributed to by the Company
for  the  benefit  of any of its officers or other employees.  The Company has
heretofore  delivered to Cymedix true, complete and correct copies of (i) each
Benefit  Plan,  (ii) the most recent annual report on Form 5500 filed with the
Internal  Revenue  Service  with  respect  to each Benefit Plan (if required),
(iii) the most recent summary plan description for each Benefit Plan for which
a  summary  plan  description is required and (iv) each trust agreement, group
annuity  contract  and other financing and funding arrangement relating to any
Benefit  Plan.

     (b)     Each Benefit Plan maintained or contributed to by the Company has
been  administered in all material respects in accordance with its terms.  The
Company  and  all  of  its  Benefit  Plans  are  in compliance in all material
respects  with  the applicable provisions of ERISA and the Code.  All material
reports,  returns  and  similar  documents  with  respect to the Benefit Plans
required  to  be  filed  with any Governmental Authority or distributed to any
Benefit  Plan  participant  have  been  duly  and timely filed or distributed.
There  are  no lawsuits, actions, termination proceedings or other proceedings
pending  or,  to the knowledge of the Company, threatened against or involving
any  of  its  Benefit Plans and, to the knowledge of the Company, there are no
investigations  by  any  Governmental Authority or other claims (except claims
for  benefits payable in the normal operation of the Benefit Plans) pending or
threatened  against  or  involving  any  of its Benefit Plans or asserting any
rights  to  benefits  under  any  Benefit  Plan  that  individually  or in the
aggregate  would  have  a  Material  Adverse  Effect.  To the knowledge of the
Company, there are no unasserted claims pending or threatened that if asserted
would  have  at  least  a  reasonable possibility of an adverse determination.

     (c)     With respect to all Benefit Plans maintained or contributed to by
the  Company,  (i)  all  contributions  to and payments from the Benefit Plans
required  thereby or by ERISA section 302 or Code section 512 have been timely
made,  (ii) there has been no application for or waiver of the minimum funding
standards  imposed  by  Code  section  512  and  (iii)  no Pension Plan has an
Aaccumulated  funding deficiency@ within the meaning of Code section 412(a) as
of  the  most  recent  plan  year.

     (d)       No Aprohibited transaction,@ as defined in Code section 4975 or
ERISA  section  406, has occurred that involves the assets of any Benefit Plan
and  that  could  subject  the  Company  or  any  of its  employees or, to the
knowledge  of  the Company, a trustee, administrator or other fiduciary of any
trusts  created  under  any  of  its  Benefit  Plans  to the tax or penalty on
prohibited transactions imposed by ERISA section 4975 or the sanctions imposed
under  Title  I  of ERISA.  No Pension Plan maintained by the Company has been
terminated,  nor  has  there  been any Areportable event,@ as defined in ERISA
section  4043  and  the regulations thereunder, with respect thereto.  Neither
the  Company  nor  any trustee, administrator or other fiduciary of any of its
Benefit  Plans  nor  any  agent  of  any  of  the foregoing has engaged in any
transaction  or  acted  or  failed  to  act in a manner that could subject the
Company to any liability for breach of fiduciary duty under ERISA or any other
applicable  law.

     (e)        At no time during the last five years has the Company (i) been
required  to  contribute  to  any  multiemployer  plan,  as defined in ERISA
section  4001(a)(3), for the benefit of any of its officers or other employees
of  the Company, (ii) incurred any withdrawal liability, within the meaning of
ERISA  section  4201,  with  respect  to  any  that  multiemployer plan, which
liability has not been fully paid as of the date hereof, or (iii) announced an
intention  to  withdraw,  but  not  yet  completed  such withdrawal, from that
multiemployer  plan.    If the Company were to make a complete withdrawal from
any  multiemployer  plan,  within  the  meaning  of  ERISA  section  4203, the
withdrawal  liability  would  not  exceed  $50,000  in  the  aggregate.

     (f)          With  respect  to any Benefit Plan of the Company that is an
employee welfare benefit plan, except as disclosed in Schedule 5.12, (i) it is
                                                      -------------
not  unfunded  or  funded  through a welfare benefits fund, as defined in Code
section  419(e),  (ii) it organized as a group health plan, as defined in Code
section  5000(b)(1),  it complies in all material respects with the applicable
requirements  of  Code  section  4980B(f)  and  (iii)  it  may  be  amended or
terminated  without  material  liability  to  the  Company.

     (g)       The Company has no current or projected liability or contingent
obligation  in  respect of medical or other benefits for its retired or former
employees.

     (h)    Except  as  set  forth in Schedule 5.12, (i) no employee or former
                                      -------------
employee  of  the  Company  will  become  entitled  to  any bonus, retirement,
severance, job security or similar benefit or any enhanced benefit solely as a
result  of  the transactions contemplated hereby, alone or in conjunction with
any  other  events  or occurrences, and (ii) no amount payable to any employee
under  any  Benefit  Plan  or other arrangement of the Company will fail to be
deductible  by  reason  of  Code  section  280G.

     (i)         The Company has not (i) engaged in a transaction described in
ERISA  section  4069  that could subject it to liability at any time after the
date hereof or (ii) engaged in any act or omission that could result in fines,
penalties,  taxes  or  related  charges  under  ERISA.

     (j)        No compensation payable by the Company to any of its employees
under  any  existing contract, Benefit Plan or other employment arrangement or
understanding  (including  by  reason of the transactions contemplated hereby)
would  be  subject  to  disallowance  under  Code  section  162(m).

     5.13    ABSENCE  OF  CHANGES  OR EVENTS.  Except as set forth in Schedule
                                                                      --------
5.13, (i) since the date of the  Company Balance Sheet, there has not occurred
any  event  or events or arisen any change of affairs that, individually or in
the aggregate, has had or could have a Material Adverse Effect, (ii) since the
date  of  the  Company  Balance  Sheet,  the  business of the Company has been
conducted  in  the  ordinary  course  and  in substantially the same manner as
previously  conducted,  (iii)  the  Company  has  made  all reasonable efforts
consistent  with  past practices to preserve its relationships with customers,
suppliers and others with whom it deals, and (iv) from the date of the Company
Balance  Sheet,  the Company has not taken any action that, if taken after the
date  of this Agreement, would constitute a breach of any of its covenants set
forth  herein.

     5.14    COMPLIANCE  WITH  APPLICABLE  LAWS.   (a)  Except as set forth on
Schedule  5.14, (i) the Company is in compliance in all material respects with
     ---------
all  applicable  statutes,  laws, ordinances, rules, orders and regulations of
any  Governmental  Authority  applicable  to  its  business  and  operations,
including  those  relating  to occupational health and safety (for purposes of
this  Section  5.14, AApplicable Laws@), and (ii) the Company has not received
any  communication  since  its  inception  from  a Governmental Authority that
alleges  its  failure  to  comply  in any material respect with any Applicable
Laws.

     (b)       The Company has provided Cymedix with all environmental reports
relating  to  the  facilities  and  operations  of  the  Company identified in
Schedule  5.14  (for  purposes of this Section 5.14, Environmental Reports).
       -------
The  Company  has  not  received  any  oral  or  written  communication from a
Governmental  Authority  that  alleges  its  failure  to  comply  with  any
Environmental  Laws  in  any  manner  that has not been finally resolved.  The
Company holds and is in compliance with all permits, licenses and governmental
authorizations  required  to  conduct  its  business under Environmental Laws.
Except  as  set  forth in Schedule 5.14, the Company is in compliance with all
                          -------------
Environmental  Laws  and  is  not  subject  to  any  judgment, decree or order
relating  to  compliance  with  any  Environmental  Law or to investigation or
cleanup  of  Hazardous Materials under any Environmental Law.  The Company has
no  contingent  liabilities  in respect of its business in connection with any
Hazardous  Materials  that,  individually  or  in  the aggregate, would have a
Material  Adverse  Effect.  Except as set forth in Schedule 5.14, there are no
                                                   -------------
aboveground  or  underground storage tanks on any property of the Company, and
all former underground storage tanks have been closed or removed in accordance
with  all  Environmental  Laws.

     5.15   EMPLOYEE AND LABOR MATTERS.  Except as set forth in Schedule 5.15,
                                                                -------------
(a)  there is, and during the last five years there has been, no labor strike,
dispute,  work  stoppage  or  lockout pending or, to its knowledge, threatened
against  or  affecting  the  Company,  (b)  to  its  knowledge,  no  union
organizational  campaign  is  in progress with respect to the employees of the
Company and no question exists concerning representation of its employees, (c)
the  Company  is  not  engaged  in  any unfair labor practice, (d) there is no
unfair  labor  practice  charge  or  complaint  pending  or, to its knowledge,
threatened  against the Company before the National Labor Relations Board, (e)
there are no pending or, to its knowledge, threatened union grievances against
the  Company  that  would have a Material Adverse Effect if determined against
the  Company,    (f)  there  are  no  pending or, to its knowledge, threatened
charges  against  the Company or any current or former employee of the Company
before  the  Equal  Employment  Opportunity  Commission  or any state or local
agency responsible for the prevention of unlawful employment practices and (g)
the Company has not received notice during the past two years of the intent of
any  Governmental  Authority  responsible  for  the  enforcement  of  labor or
employment  laws  to conduct an investigation of or affecting the Company and,
to  its  knowledge,  no  such  investigation  is  in  progress.

     5.16  LICENSES; PERMITS.  The Company has obtained all material licenses,
permits and authorizations from Governmental Authorities that are necessary or
desirable  for  the  conduct of its business.  Except as set forth in Schedule
                                                                      --------
5.16,  (a)  all required licenses, permits and authorizations are validly held
  --
by the Company, (b) the Company has complied in all material respects with all
terms  and  conditions  thereof  and  (c)  the  same  will  not  be subject to
suspension,  modification,  revocation  or  nonrenewal  as  a  result  of  the
execution  and  delivery  of  this  Agreement  or  the  consummation  of  the
transactions  contemplated  hereby.

     5.17  DISCLOSURE.  No representation or warranty of the Company contained
in  this  Agreement,  no  statement  contained in any document, certificate or
Schedule  and  no  data  in  connection  with  the due diligence investigation
contemplated by Section 6.2(a) furnished or to be furnished by or on behalf of
the  Company  to  Cymedix  or  any  of  its  representatives  pursuant to this
Agreement  contains or will contain any untrue statement of a material fact or
omits  or  will  omit  to  state  any material fact necessary, in light of the
circumstances  under  which  it  was  or  will  be  made, in order to make the
statements  herein  or therein not misleading or necessary to fully and fairly
provide  the  information  required  to  be  provided  therein.

     ARTICLE  VI    COVENANTS

     6.1          BRIDGE  LOANS.    (a)  The Company has received Bridge Loans
aggregating  $227,500 as of the date of this Agreement.  During the balance of
the Bridge Period, the Company will continue to make semi-monthly Bridge Loans
to  Cymedix  in  the  following amounts on the dates (the Bridge Loan Funding
Schedule)  set  forth  below:

<TABLE>
<CAPTION>

     DATE  OF  BRIDGE  LOAN          AMOUNT  OF  BRIDGE  LOAN
     ----------------------          ------------------------
            <S>                            <C>
     November  28,  1997                   $35,000
     December  15,  1997                    35,000
</TABLE>
 

     (b)          The Bridge Loan Funding Schedule is subject to the following
modifications:

     (i)         Prior to the Company=s receipt of net sale proceeds exceeding
$200,000  from  a recent asset sale, it will have the right, to the extent its
working  capital  is  inadequate  to  timely adhere to the Bridge Loan Funding
Schedule,  to  (A)  fund each semi-monthly Bridge Loan in installments and (B)
delay  funding  any  full semi-monthly Bridge Loan for up to six business days
after  the  date  specified  in  the  Bridge  Loan  Funding  Schedule

     (ii)          After  the Company=s receipt of net sale proceeds exceeding
$200,000  from a recent asset sale, Cymedix will have the right, to the extent
its  working capital is inadequate to meet its current obligations, to request
the  Company  to  make  additional  loan=s  to enable Cymedix to satisfy those
obligations.    The Company will have sole discretion over the funding, timing
and  amount  of  any additional loans.  If made by the Company, the additional
loans  will  be  advanced  on  the  same  terms  as  the  Bridge  Loans.

     (iii)       The Bridge Loan Commitment will end (A) on the Effective Date
if the Merger is completed before the end of the Bridge Period or (B) upon any
declaration  of  a  Company  Termination  Event  under  Section  8.2.

     (c)     Each Bridge Loan and any additional loan under Section 6.1(b)(ii)
will  be  evidenced  by  a Bridge Note to be executed and delivered by Cymedix
upon receipt thereof.  Cymedix acknowledges that it has heretofore granted the
Company,  as  collateral security for the Bridge Loans, a security interest in
all  of  its  assets,  subject  to  the  existing security interest granted by
Cymedix to Global Med Technologies, Inc. as collateral security for the Global
Note.

     (d)         Cymedix will continue to apply proceeds from the Bridge Loans
substantially  as  set  forth  in  the  Cymedix  Budget.

     6.2      ACCESS; SUPPLEMENTAL DISCLOSURE.  (a)  During the balance of the
Diligence  Period,  each  party shall continue to give the other party and its
representatives, employees, consultants, counsel and accountants (for purposes
of  this  Section  6.2,  Representatives),  upon  request,  access  to  its
personnel,  properties,  offices,  books  and records and promptly provide the
other  party  and  its  Representatives all available  financial and operating
data  and  other  information  and assistance with respect to its business and
properties  as  it  may  request  from  time  to  time.   Without limiting the
foregoing, Cymedix shall cooperate with the Company=s auditors in their review
of  the  business  and  operations  of  Cymedix and permit them to discuss the
procedures  and  review the work papers used by Cymedix and its accountants in
the  preparation  of  its  financial  statements  since  its  inception.

     (b)      Until the earlier of the Effective Date or the end of the Bridge
Period,  each  party  shall  have  the continuing obligation  to supplement or
amend its Schedules with respect to any matter hereafter arising or discovered
that,  if  existing  or  known  on the date of this Agreement, would have been
required  to  be  set  forth  or  described  in  its  Schedules.

     (c)      Each party shall promptly notify the other party of, and furnish
any  information  the  other party may reasonably request with respect to, the
occurrence of any event or condition or the existence to its  knowledge of any
fact that would cause any of the conditions to the other party=s obligation to
consummate  the  Merger  under  Article  VII  to  be  unfulfilled.

     6.3      CONDUCT OF BUSINESS PENDING THE MERGER.  (a)  During the balance
of  the  Bridge  Period,   Company will conduct its operations in the ordinary
course  of  business  in  a  manner  consistent  with  past  practices.

     (b)         During the balance of the Bridge Period, Cymedix will not (i)
amend  its  Certificate  of  Incorporation  or Bylaws, (ii) declare or pay any
dividend or make any other distribution to its shareholders upon any shares of
its capital stock, (iii) redeem or otherwise acquire any shares of its capital
stock  or  issue  or  amend  any capital stock or any option, warrant or right
relating  thereto  or  any securities convertible into or exchangeable for any
shares  of  capital stock, (iv) adopt or amend in any respect any Benefit Plan
or  collective bargaining agreement, except as required by law after providing
written  notice to the Company, (v) grant to any executive officer or employee
any  increase  in  compensation  or  benefits, except as may be required under
existing  agreements  or  approved  by the Company, (vi) except for the Bridge
Loans,  incur  or assume any liabilities, obligations or indebtedness, in each
case  for  borrowed  money,  or  guarantee  any  liabilities,  obligations  or
indebtedness,  (vii)  permit,  allow  or  suffer  any  of its assets to become
subject to any mortgage, lien, security interest, encumbrance or other similar
restriction  of  any  nature, (viii) waive any claims or rights of value, (ix)
pay,  loan  or  advance  any  amount to, or sell, transfer or lease any of its
assets  to,  or  enter  into  any  agreement  or  arrangement with, any of its
Affiliates,  (x)  make  any  change  in any method of accounting or accounting
practice  or  policy,  (xi)  acquire  by  merging or consolidating with, or by
purchasing  a substantial portion of the assets of, or by any other means, any
business  or  any  corporation,  partnership,  association  or  other business
organization  or  division  thereof  or  otherwise  acquire  any assets for an
aggregate  purchase price in excess of $5,000, (xii) make or incur any capital
expenditure  that  individually  or  in the aggregate are in excess of $5,000,
(xiii)  sell,  lease, license or otherwise dispose of any of its assets except
as  provided  in  Section 6.3(c), (xiv) enter into any lease of real property,
except  any renewals of existing leases on market terms in the ordinary course
of  business,  (xv) enter into or amend or supplement any material Contract or
(xvi)  or  agree, whether in writing or otherwise, to do any of the foregoing.
On  the  Effective  Date,  Cymedix  will not have any liabilities in excess of
$120,000  other  than  the  Bridge  Loans, the Global Note and liabilities for
attorneys'  fees  incurred  by  Cymedix  in  connection  with  the Merger (the
Liability  Cap),  provided  that the Liability Cap shall be increased by the
principal  amount  of  any Bridge Loans or portions thereof that have not been
funded  by  the  Effective  Date  in  accordance  with the Bridge Loan Funding
Schedule.

     (c)         During the balance of the Bridge Period, Cymedix will use its
best efforts to enter into license agreements for installation and sponsorship
of  its  LYNX-MC  software product with managed care organizations and medical
centers.

     6.4          OTHER  TRANSACTIONS.  During the Diligence Period, except as
otherwise  provided  herein,  Cymedix  and  if  its  officers,  directors,
shareholders or representatives shall neither initiate or solicit any proposal
or  offer from any Person regarding any Competing Transaction nor encourage or
facilitate  a  Competing  Transaction  by  providing  nonpublic information or
conducting  any  discussions or negotiations or entering into any agreement or
understanding  for a Competing Transaction.  These restriction shall terminate
if (i) any Bridge Loan payable after the date of this Agreement is not made in
accordance  with  Section 6.1, (ii) not apply to any negotiations or Competing
Transaction  with  Shared  Medical  Systems  Corporation if Cymedix shall have
received  a  Competing  Offer from that Person prior to September 23, 1997 and
(iii)  not  prevent  Cymedix  from  entering into negotiations or completing a
Competing  Transaction  if  and  to  the  extent  that  (A)  the Cymedix Board
determines in good faith that pursuing the Competing Proposal is necessary for
compliance with its fiduciary duties to shareholders under applicable law, (B)
prior to entering into negotiations Cymedix shall have provided written notice
to the Company that includes the terms of the Competing Proposal, the identity
of the Person making the Competing Proposal and the fact that clause (A) above
has been satisfied and (C) the instrument memorializing the Competing Proposal
provides  for  the  Company to receive a break-up fee in the amount of $75,000
from  Cymedix  or  its  successor  within  five  days  after completion of the
Competing  Transaction  contemplated  thereby.

     6.5        CONSENT OF CYMEDIX SHAREHOLDERS.  As soon as practicable after
the  execution of this Agreement, Cymedix will use its best efforts to solicit
from  its  shareholders  written consents in lieu of a meeting to approve this
Agreement  in accordance with the applicable provisions of the California Act.
The  solicitation materials prepared by Cymedix for that purpose shall contain
(a)  a  copy  of  the unaudited financial statements of Cymedix referred to in
Section  4.6(a),  (b)  a summary of the material provisions of this Agreement,
including  paragraphs  (b)  and  (c)  of  Section  6.10,  (c)  a  copy of this
Agreement,  and  (d) of copy of (i) the Company=s Annual Report on Form 10-KSB
for  the  year ended December 31, 1996, (ii) the Company=s Proxy Statement for
its 1996 annual meeting of shareholders and (iii) its Quarterly Report on Form
10-QSB  for  the  quarter ended June 30, 1997 or, if available at the time the
solicitation materials are mailed, its Quarterly Report on Form 10-QSB for the
quarter  ended  September 30, 1997.  If the Company=s Quarterly Report on Form
10-QSB  for  the  quarter  ended September 30, 1997 is unavailable at the time
solicitation materials are mailed by Cymedix, it shall be mailed separately to
shareholders  of  Cymedix  when  available  before  the  Closing.

     6.6          CERTIFICATES  OF MERGER.  Upon satisfaction or waiver, where
permitted, of the conditions set forth in Article VII, Cymedix and the Company
shall execute and file the Merger Certificates in accordance with Section 1.2.

     6.7          ASSUMPTION OF STOCK OPTIONS AND DEBT.  (a)  On the Effective
Date,  the  Company  shall assume all outstanding Cymedix Stock Options, which
will  thereafter  become  exercisable for the number of Reserved Merger Shares
that  the  option  holders  would  have  received  in the Merger at the Common
Exchange Rate in exchange for the shares of Cymedix Common Stock issuable upon
exercise thereof prior to the Effective Date, on the same terms and conditions
in  effect  immediately prior to the Merger.  As soon as practicable after the
Effective  Date,  the  Company  shall  execute  and  deliver option agreements
reflecting  the  foregoing  to  holders  of outstanding Cymedix Stock Options.

     (b)       On the Effective Date, the indebtedness evidenced by the Global
Note shall be assumed by the Merger Sub and guaranteed by the Company, and the
Global  Note  will  become  convertible,  following  any payment default, into
Company  Common  Stock  based  on  the  Common  Exchange  Rate.

     (c)          On  the  Effective Date, all outstanding accounts payable of
Cymedix  shall be assumed by the Merger Sub and guaranteed by the Company, and
the assumed obligations shall be timely paid by the Merger Sub or the Company,
provided  that the account payable to Stahl & Zelmanovitz, counsel to Cymedix,
shall  be  paid $10,000 at the Closing and the balance in monthly installments
of  not  less  than  $5,000  commencing  in the first month after the Closing.

     6.8      BOARD REPRESENTATION.  (a)  Contemporaneously with the execution
of  this  Agreement,  Cymedix  shall take all action necessary to increase the
size  of  the  Cymedix  Board  to  consist  of  five directors and to fill the
resulting  vacancy with a designee of the Company.  On the Effective Date, the
Cymedix Board will be disbanded in accordance with the California Act, and the
former  members  thereof  shall  have no right to membership on the Merger Sub
Board  or  the  Company  Board  except  as  provided  in  Section  6.8(b).

     (b)          On  the  Effective  Date,  the Company shall take all action
necessary  to  increase  the  size  of  the  Company  Board to consist of four
directors  and  to  fill the resulting vacancy with a designee of Cymedix.  If
the  Merger  is  consummated,  the Company shall include one designee of Keith
Berman  for  election  to  the  Company Board at each meeting of the Company=s
shareholders where directors of the Company are elected during the three years
following  the  Effective  Date.

     6.9     EMPLOYMENT AGREEMENTS AND RELATED MATTERS.  (a)  On the Effective
Date,  the  Merger  Sub  shall  enter  into  mutually  acceptable  employment
agreements  on  customary  industry  terms  (the AEmployment Agreements@) with
Keith  Berman  and  Barbara Asbell and shall offer employment to other current
employees  of  Cymedix designated by Mr. Berman upon notice to the Company not
less than five days prior to the Closing (collectively, Cymedix Management).
The  obligations  of  the  Merger Sub under the Employment Agreements shall be
guaranteed  by  the  Company.    The Employment Agreement with Mr. Berman will
provide  for  his  appointment  as  President  of  the  Merger  Sub.

     (b)          At  the  Closing, the members of Cymedix Management or their
designees (the Optionees) will be entitled to receive options to purchase an
aggregate  of  1.2 million shares of Company Common Stock at the closing price
of  the  Company  Common  Stock  on the business day immediately preceding the
Effective Date, vesting in one-third cumulative annual installments commencing
on  the  first  anniversary  of the Effective Date (the Management Options).
The  number of Management Options issuable to each Optionee will be determined
by  Mr. Berman upon notice to the Company not less than five days prior to the
Closing.

     6.10   REGISTRATION OF MERGER SHARES.  (a)  If the Merger is consummated,
the  Company  shall  (i)  file  a registration statement on Form S-3 under the
Securities  Act  (the  Registration  Statement) on or before April 20, 1998,
covering  the  resale  of  the  Merger  Shares  (including the Reserved Merger
Shares)  by  the  beneficial  owners  thereof (collectively, the Holders) in
accordance  with  Rule 415 under the Securities Act, (ii) use its best efforts
to  cause  the  Registration  Statement  to  be  declared effective as soon as
practicable  thereafter,  (iii)  keep  the  Registration  Statement current in
accordance  with  the  applicable  provisions  of the Securities Act until the
first  anniversary  of  the  Effective  Date, (iv) file documents required for
state securities or Ablue sky@ clearance in jurisdictions specified in writing
by  the  Holders  and  use  its  best  efforts  to  cause the Merger Shares so
registered  to  be  and  remain  qualified thereunder where qualifications are
required  to  permit  the  public  sale thereof and (vii) bear all expenses in
connection  with  the  procedures  described  in this Section 6.10, other than
selling  commissions  and  fees  and expenses of counsel or other advisers, if
any,  to  the  Holders.

     (b)     By acceptance of the Merger Shares, each Holder will be deemed to
represent  and  warrant  to  the  Company that the Holder (i) either (A) is an
Aaccredited investor,@ as defined in Rule 501 under the Securities Act, or (B)
has such knowledge and experience in financial and business matters that he is
capable  of  evaluating the merits and risks of the Merger, (ii) has received,
reviewed  and considered all information deemed relevant in making an informed
decision about the Merger, (iii) is acquiring Merger Shares for investment and
with no present intention of distributing or reselling them except as provided
in  the  Registration  Statement  and (iv) is aware that the Merger Shares (A)
have  not been registered with the SEC or any state securities commission, (B)
will  be  deemed  to be Arestricted securities@ for purposes of the Securities
Act  and  (C)  may  not  be sold or otherwise transferred in the absence of an
exemption  from  the  registration  requirements  of  the  Securities  Act and
applicable  state  securities  laws  or  as  otherwise  contemplated  by  the
Registration  Statement.

     (c)         By acceptance of Merger Shares, each Holder will be deemed to
agree  to  (i)  refrain  from publicly selling or offering for sale any Merger
Shares  until  the  Registration  Statement  is  effective,  (ii) refrain from
effecting any disposition of Merger Shares that would constitute a sale within
the  meaning  of the Securities Act except as contemplated in the Registration
Statement  and  (iii)  limit  sales  in  each month during the period from the
effectiveness of the Registration Statement until the first anniversary of the
Effective  Date  to  5%  of  the  Merger Shares received by that Holder in the
Merger.    The Company will be entitled to place stop orders with the transfer
agent  for  the  Company  Common  Stock  to  implement  this  restriction.

     (d)     At the time the Registration Statement is declared effective, the
Company  shall furnish to the Holders copies of the prospectus included in the
Registration  Statement  in conformity with the requirements of the Securities
Act,  together  with any other documents the Holders may reasonably request to
facilitate  the  public  sale  or  other  disposition  of  the  Merger Shares.

     (e)         The Company agrees to indemnify and hold harmless each Holder
(and each person who controls a Holder within the meaning of Section 15 of the
Securities Act) from and against any losses, claims, damages or liabilities to
which  the  Holder  may become subject (under the Securities Act or otherwise)
insofar  as  those  losses,  claims,  damages  or  liabilities  (or actions or
proceedings  in  respect  thereof)  arise  out of or are based upon any untrue
statement  of  a  material  fact contained or incorporated by reference in the
Registration  Statement  or arise out of any failure by the Company to fulfill
any  undertaking  included in the Registration Statement, and the Company will
reimburse  the  Holder  for any legal or other expenses reasonably incurred in
investigating, defending or preparing to defend any such action, proceeding or
claim;  provided, however, that the Company shall not be liable in any case to
the extent that the loss, claim, damage or liability arises out of or is based
upon  an  untrue statement made in the Registration Statement in reliance upon
and  in  conformity with written information furnished to the Company by or on
behalf  of  the Holder specifically for use in preparation of the Registration
Statement  The  term  Auntrue statement@ shall include any untrue statement or
alleged  untrue statement, or any omission or alleged omission to state in the
Registration  Statement  a  material  fact  required  to  be stated therein or
necessary  to  make  the statements therein, in the light of the circumstances
under  which  they  were  made,  not  misleading.

6.11    CONFIDENTIALITY.    The  parties (a) acknowledge that the transactions
contemplated  by  this  proposal  will  require  them  to  share  Confidential
Information  and  (b) agree that, during the Bridge Period  and, if the Merger
is  not  consummated,  at  all  times thereafter, each party will (i) hold the
other party's Confidential Information in strict confidence, (ii) not copy the
other  party's Confidential Information or disclose any portion thereof to any
third  party  without  the prior written consent of the other party, (iii) not
make any use of the other party=s Confidential Information except for the sole
purpose  of performing its due diligence review hereunder and (iv) immediately
return  to  the  other  party  or  destroy, as the other party may direct, all
tangible  records  embodying the other party=s Confidential Information in its
possession,  custody  or  control  upon  any  termination  of  this Agreement.

     6.12    PUBLICITY.    Cymedix  and  the Company agree that, from the date
hereof  through  the  Effective  Date,  no  public  release  or  announcement
concerning  the  transactions  contemplated  hereby  shall be issued by either
party without the prior consent of the other party (which consent shall not be
unreasonably  withheld),  except  any  release  or  announcement  that  may be
required  by  law  or  the  rules  or  regulations  of any national securities
exchange  or association, in which case the party required to make the release
or announcement shall allow the other party reasonable time to comment thereon
in  advance  of  its  issuance;  provided,  however,  that each party may make
internal  announcements to its employees that are consistent with the parties=
prior  public disclosures regarding the transactions contemplated hereby after
reasonable  prior  notice  to  and  consultation  with  the  other  party.

     6.13    FURTHER  COOPERATION.   At the request of any party hereto either
before  or  after  the  Effective
Date,  each  party shall take all actions and deliver all documents reasonably
necessary  or  appropriate  to  carry  out  the  terms  and provisions of this
Agreement.   Each of the parties will use all reasonable efforts to obtain any
necessary  waivers,  consents  and approvals, effect all necessary filings and
take  all  actions  necessary  or  appropriate  to consummate the transactions
contemplated  by  this  Agreement.

     ARTICLE  VII    CONDITIONS  PRECEDENT

     7.1       CONDITIONS TO THE COMPANY=S OBLIGATIONS.  The obligation of the
Company  to  effect  the  transactions  contemplated hereby are subject to the
satisfaction  or,  subject to the provisions of Section 7.3, the waiver of the
following  conditions:

     (a)          This  Agreement  shall have been approved and adopted by the
holders  of a majority of the Cymedix Common Stock, Cymedix Series A Preferred
Stock  and  Cymedix  Series B Preferred Stock, voting as separate classes, and
none  of  the  shareholders  of  Cymedix  shall  have  sought to perfect their
dissenters=  rights  under  the  California  Act.

(b)          No  statute, rule, regulation, executive order, decree, temporary
restraining order, preliminary or permanent injunction or other order enacted,
entered,  promulgated,  enforced  or  issued  by any Governmental Authority or
other legal restraint or prohibition preventing the Merger shall be in effect.

     (c)          There shall not be pending or threatened by any Governmental
Authority any suit, action or proceeding challenging or seeking to restrain or
prohibit the Merger or seeking to obtain any material damages from the Company
or  any of its Affiliates in connection with the Merger or seeking to prohibit
the  Company from effectively controlling in any material respect the business
or  operations  of  Cymedix.

     (d)          The  Company  shall have received an opinion dated as of the
Effective  Date from Stahl & Zelmanovitz, counsel to Cymedix, substantially in
the  form  of  Exhibit  A.
               ----------

     (e)          Keith Berman shall have executed and delivered an Employment
Agreement.

     (f)     Cymedix shall have performed or complied in all material respects
with  all obligations and covenants required by this Agreement to be performed
or  complied  with  by  Cymedix.

     (g)          The  representations  and warranties of Cymedix made in this
Agreement  shall  be  true  and  correct  in  all  material respects as of the
Effective  Date  as  though  made  as  of that time, except to the extent they
expressly  relate  to  an  earlier  date, in which case they shall be true and
correct  in  all  material  respects  on  and  as  of  that  earlier  date.

     (h)       Cymedix shall have delivered to the Company a certificate dated
as  of  the  Effective Date and signed by an authorized officer of Cymedix (i)
confirming  that  the  conditions  set forth in paragraphs (e) and (f) of this
Section 7.1 have been satisfied, (ii) providing a true and correct listing, as
of  the  Effective  Date,  of  the  holders  of  Cymedix Common Stock, Cymedix
Preferred  Stock  and Cymedix Stock Options, setting forth for each holder (A)
the  name  and  residence  address  of the holder, (B) the number and class of
shares  or  options  held  by  the  holder and (C) the number of Merger Shares
issuable  to  the holder in the Merger or the number of Reserved Merger Shares
issuable  to  the holder upon exercise of Cymedix Stock Options assumed in the
Merger, and (iii) confirming whether Cymedix had reasonable grounds to believe
that  each  holder  listed  under  clause  (ii)  of this Section 7.1(h) was an
Aaccredited  investor@  as defined in the Securities Act at the time shares or
options  were  issued  to  the  holder.

     (i)     The Company shall not have concluded in its reasonable discretion
based  on  its  due  diligence  investigation that (i) the unaudited financial
statements  of  Cymedix  for  the  year  ended December 31, 1996 do not fairly
present  the  financial  position  of  Cymedix  as of the date thereof and the
results of its operations for the period then ended, (ii) Cymedix has material
liabilities  or  obligations  other  than (A) as disclosed, reflected or fully
reserved  against  in  the  Cymedix  Balance  Sheet and the notes incorporated
therein, (B) items set forth in the Schedules delivered by Cymedix pursuant to
Article IV, (C) liabilities and obligations incurred in the ordinary course of
business  consistent  with past practice since the date of the Cymedix Balance
Sheet  and (4) Taxes, (iii) Cymedix shall have failed to adhere to the Cymedix
Budget  and  the  failure materially reduces the benefits of the Merger to the
Company  or  (iv)  an  event  has  occurred,  including  the  commencement  of
litigation against Cymedix by or on behalf of one or more of its shareholders,
that  can  reasonably  be  expected  to  have  a  Material  Adverse  Effect.

     7.2          CONDITIONS TO THE OBLIGATIONS OF CYMEDIX.  The obligation of
Cymedix  to  effect  the  transactions  contemplated hereby are subject to the
satisfaction  or,  subject to the provisions of Section 7.3, the waiver of the
following  conditions:

     (a)      The Company shall have taken all actions required to ensure that
the  Merger  Shares shall have been approved for inclusion on the Nasdaq Small
Cap  Market.

     (b)       The Company shall have made all Bridge Loans in accordance with
Section  6.1.

     (c)      Cymedix shall have received an opinion dated as of the Effective
Date  from Lyle B. Stewart, P.C., counsel to the Company, substantially in the
form  of  Exhibit  B.
          ----------

     (d)     The Merger Sub shall have entered into Employment Agreements with
Keith  Berman  and  Barbara  Asbell,  and  the  Company  shall have issued the
Management  Options  to  the  Optionees  and  guaranteed  the  Merger  Sub=s
obligations  under  the  Employment  Agreements.

     (e)       The Merger Sub and the Company shall have performed or complied
in  all  material respects with all obligations and covenants required by this
Agreement  to be performed or complied with by the Merger Sub and the Company.
The  Company  shall  have  delivered  to Cymedix a certificate dated as of the
Effective  Date  and signed by an authorized officer of the Company confirming
the  foregoing.

     (f)        The representations and warranties of the Company made in this
Agreement  shall  be  true  and  correct  in  all  material respects as of the
Effective  Date  as  though  made  as  of that time, except to the extent they
expressly  relate  to  an  earlier  date, in which case they shall be true and
correct  in  all  material  respects  on  and  as  of  that  earlier  date.

     (g)       The Company shall have delivered to Cymedix a certificate dated
as  of  the  Effective Date and signed by an authorized officer of the Company
confirming  that  the  conditions  set forth in paragraphs (e) and (f) of this
Section  7.2  have  been  satisfied.

     (h)         Cymedix shall not have concluded in its reasonable discretion
based  on  its due diligence investigation that (i) any documents filed by the
Company  under  the Exchange Act within the last two years contained an untrue
statement  of  a material fact or omitted to state a material fact required to
be  stated  therein  or  necessary in order to make the statements therein, in
light  of  the  circumstances under which they were made, not misleading, (ii)
the Company=s unaudited financial statements for the six months ended June 30,
1997  do not fairly present the consolidated financial position of the Company
as  of  the date thereof and the results of its operations for the period then
ended  (subject  to  normal    adjustments)  or (iii) the Company has material
liabilities  or  obligations  other  than (A) as disclosed, reflected or fully
reserved  against  in  the  Company  Balance  Sheet and the notes incorporated
therein,  (B)  items  set  forth  in  the  Schedules  delivered by the Company
pursuant  to  Article  V,  (C)  liabilities  and  obligations  incurred in the
ordinary  course  of  business consistent with past practice since the date of
the  Company  Balance  Sheet  and  (4)  Taxes  or  (iv) an event has occurred,
including  the  commencement of litigation against the Company by or on behalf
of  one or more of its shareholders, that can reasonably be expected to have a
Material  Adverse  Effect.

     7.3          FRUSTRATION  OF CLOSING CONDITIONS.  Neither the Company nor
Cymedix  may  rely on the failure of any condition set forth in Section 7.1 or
7.2,  respectively,  to be satisfied if the failure was caused by that party=s
failure  to  act  in  good faith or to use all reasonable efforts to cause the
Merger  to  occur.

     7.4          WAIVER  OF  CERTAIN CONDITIONS.  The conditions described in
Sections  7.1(a),  7.1(c),  7.2(a)  and  7.2(i)  cannot  be  waived.

     ARTICLE  VIII    MODIFICATION  OR  TERMINATION

     8.1      MODIFICATION.  If any event shall occur or any matter be brought
to  the  attention  of  the Company that, in its sole judgment, materially and
adversely affects its ability to consummate the Merger,  this Agreement may be
modified  or  amended  with the consent of Cymedix to take the event or matter
into  account.    In that event, the shareholders of Cymedix shall be notified
and  given an opportunity, during a period of not less than 20 days, to revoke
their  consents  to  the  approval  and  adoption  of  this  Agreement.
8.2       TERMINATION.  (a)  Company Termination Event.  This Agreement may be
                             -------------------------
terminated  by  the Company and the transactions contemplated hereby abandoned
at  any  time  prior  to  the  filing of the Merger Certificates if any of the
following  events  (each  a  Company Termination Event) shall have occurred:

     (i)        Cymedix shall have failed to satisfy any of the conditions set
forth  in Sections 7.1(a) through 7.1(e) or any of those conditions shall have
become incapable of fulfillment and shall not have been waived by the Company;

     (ii)       Cymedix shall have failed to satisfy any of the conditions set
forth  in Sections 7.1(f) through 7.1(i) or any of those conditions shall have
become  incapable  of fulfillment and the failure or nonfulfillment materially
reduces the benefits of the Merger to the Company; provided, however, that (A)
Schedule  4.5  may  be  amended  from  time  to time by Cymedix to reflect the
exercise  of  outstanding  stock  options  or  the  conversion  of outstanding
convertible  securities  or  instruments  without giving rise to any claim for
breach  of  its  representations  and warranties in Section 4.5 and (B) if the
Company  shall  not  have  asserted a Company Termination Event for failure to
satisfy  the  condition  set forth in Section 7.1(f) or clauses (i) or (ii) of
Section  7.1(h) on or prior to the close of business on the tenth business day
after  the date all Schedules are delivered to the Company pursuant to Article
IV,  it  shall  not  have the right to thereafter assert a Company Termination
Event  as  a  result  of  that  failure;  or

     (iii)    Cymedix  shall  have  entered  into a definitive agreement for a
Competing  Transaction.

     (b)       Cymedix Termination Event.  This Agreement may be terminated by
               -------------------------
Cymedix  and  the transactions contemplated hereby abandoned at any time prior
to  the filing of the Merger Certificates if any of the following events (each
a  Cymedix  Termination  Event)  shall  have  occurred:

     (i)        The Company shall have failed to satisfy any of the conditions
set  forth  in Sections 7.2(a) through 7.2(d) or any of those conditions shall
have  become  incapable  of  fulfillment  and  shall  not  have been waived by
Cymedix;  or

     (ii)       The Company shall have failed to satisfy any of the conditions
set  forth  in Sections 7.2(e) through 7.2(i) or any of those conditions shall
have  become  incapable  of  fulfillment  and  the  failure  or nonfulfillment
materially  reduces  the benefits of the Merger to Cymedix; provided, however,
that  (A)    Schedule  5.5  may be amended from time to time by the Company to
             -------------
reflect  the  exercise  of  outstanding  stock  options  or  the conversion of
outstanding  convertible  securities or instruments without giving rise to any
claim  for breach of its representations and warranties in Section 5.5 and (B)
if  Cymedix shall not have asserted a Cymedix Termination Event for failure to
satisfy  the  condition  set forth in Section 7.2(f) or clauses (i) or (ii) of
Section  7.2(h) on or prior to the close of business on the tenth business day
after  the  date all Schedules are delivered to Cymedix pursuant to Article V,
it  shall  not have the right to thereafter assert a Cymedix Termination Event
as  a  result  of  that  failure.

     (c)          This  Agreement  may  be  terminated  and  the  transactions
contemplated  hereby abandoned by either party hereto, if the Closing does not
occur  on  or  prior  to  December  31,  1997, provided that the party seeking
termination  pursuant  to this Section 8.2(c) is not in breach in any material
respect  of  any  of  its  material  representations, warranties, covenants or
agreements  contained  in  this  Agreement.

     8.3       NOTICE OF TERMINATION.  In the event a party seeks to terminate
this Agreement pursuant to Section 8.2, written notice thereof shall forthwith
be  given  to  the other party, setting forth in reasonable detail the grounds
for  termination,  whereupon  the  transactions contemplated by this Agreement
shall  be  terminated,  without further action by either party, subject to the
provisions  of  Section  8.4.

     8.4         EFFECTS OF TERMINATION.  (a)  Except as otherwise provided in
this  Section  8.4,  if  this  Agreement  is  terminated  and the transactions
contemplated  hereby  are  abandoned  as  provided  in this Article VIII, this
Agreement  shall  become  void  and  of  no  further  force  or  effect.

     (b)          Following  any Company Termination Event, in any election of
directors  of  Cymedix  during  the  period  when  any  Bridge  Loan  remains
outstanding, Cymedix will include one designee of the Company as a nominee for
election  to  the Cymedix Board, provided that this undertaking will terminate
upon  the  completion  of  any  Competing  Transaction.

     (c)        If the Company exercises its right to terminate this Agreement
pursuant  to  Section  8.2(a)(iii),  it  shall  be  entitled  to (i) receive a
break-up  fee  in  the  amount of $75,000 from Cymedix or its successor within
five  days  after  completion of the Competing Transaction referred to therein
and  (ii)  accelerate the maturity of the Bridge Loans to a date not less than
30  days  after  completion  of  the  Competing  Transaction.

     (d)       Within ten days following any Cymedix Termination Event that is
not  waived  by  Cymedix,  the  Company  will pay a break-up fee of $50,000 to
Cymedix.

     (e)     If this Agreement is terminated by either party, each party shall
return  all  documents  and  other  material received from or on behalf of the
other  party  in connection with the transactions contemplated hereby, whether
so  obtained  before  or  after  the  execution  hereof.    All  Confidential
Information  received  by  a  party  with respect to the business of the other
party  shall  be treated in accordance with the restrictions set forth herein,
which shall remain in full force and effect notwithstanding the termination of
this  Agreement.

     (f)      Nothing in this Article VIII shall be deemed to impair the right
of  either  party  to  compel  specific  performance by the other party of its
continuing  obligations  under  this  Agreement,  including the obligations of
Cymedix  under  the  Bridge  Notes, and no termination of this Agreement shall
relieve  either  party  of  its  obligations  for  expenses under Section 9.2.
 .
     ARTICLE  IX  C  MISCELLANEOUS  PROVISIONS

     9.1      SURVIVAL OF REPRESENTATIONS.  The representations and warranties
in  this  Agreement and in any certificate delivered pursuant hereto shall not
survive  the  Merger.

     9.2        EXPENSES.  Whether or not the transactions contemplated hereby
are  consummated,  all  costs  and  expenses  incurred in connection with this
Agreement  and the transactions contemplated hereby shall be paid by the party
incurring those costs or expenses, provided that the Company shall bear 50% of
the  attorneys=  fees and disbursements incurred by Cymedix in connection with
the  Merger  in  the  event  this  Agreement  is  terminated  for  any reason.

     9.3       FEES.  Each party hereto hereby represents and warrants that no
brokers,  finders  or investment bankers that may be entitled to any brokerage
fee,  finder=s  fee,  commission or investment banking fee have acted for that
party  in  connection  with  this  Agreement  or the transactions contemplated
hereby  other  than  EBM,  Inc.,  which  has  been engaged to act as financial
advisor  to  the  Company, and the Company shall bear all fees payable to that
firm.

     9.4        AMENDMENTS.  No amendment or modification of this Agreement or
waiver  of  any  provision  hereof  shall  be  effective unless it shall be in
writing,  signed  by  both  parties  hereto and implemented in accordance with
Section  8.1.

     9.5          NOTICES.    All  notices or other communications required or
permitted  to be given hereunder shall be in writing and shall be delivered by
hand,  sent  by  confirmed  fax  or delivered, postage prepaid, by registered,
certified  or express mail or reputable overnight courier service and shall be
deemed  given  when  so delivered by hand, confirmed faxed or if mailed, three
days  after mailing (one business day in the case of express mail or overnight
courier  service),  as  follows:


<PAGE>
     (i)  if  to  the  Company,

     International  Nursing  Services,  Inc.
     360  S.  Garfield  Street  -  Suite  400
     Denver,  CO  80209-3136
     Tel.  (303)  393-1515
     Fax    (303)  393-1579

     Attention:    Mr.  John  P.  Yeros



     with  a  copy  to

     Lyle  B.  Stewart,  P.C.
     3751  South  Quebec  Street
     Denver,  CO  80237
     Tel.    (303)  267-0920
     Fax    (508)  267-0922


     (ii)          if  to  Cymedix,

     Cymedix  Corporation
     100  Thousand  Oaks  Blvd.  -  Suite  117
     Thousand  Oaks,  CA  91360
     Tel:    (805)  230-1133
     Fax    (805)230-1144

     Attention:    Mr.  Keith  Berman


     with  a  copy  to:

     Stahl  &  Zelmanovitz
     430  Park  Avenue  -  18th  Floor
     New  York,  NY  10022
     Tel.:  (212)  826-6363
     Fax:    (212)  826-6785

     Attention:    Douglas  Stahl,  Esq.

     9.6     REMEDIES.  Except as expressly provided herein, this Agreement is
not  intended  to  confer  upon  any  Person any rights or remedies hereunder.

     9.7       ASSIGNMENT.  This Agreement may not be assigned by operation of
law  or  otherwise  without  the  consent  of  both  parties  hereto.

     9.8       ENTIRE AGREEMENT.  This Agreement contains the entire agreement
and  understanding  between  the  parties  hereto  with respect to the subject
matter  hereof and supersedes all prior agreements and understandings relating
thereto.    Neither  party shall be liable or bound to any other Person in any
manner  by  any  representations,  warranties  or  covenants  relating to that
subject  matter  except  as  specifically  set  forth  herein.

     9.9     SEVERABILITY.  If any provision of this Agreement (or any portion
thereof)  or the application of that provision (or any portion thereof) to any
Person  or circumstance shall be held invalid, illegal or unenforceable in any
respect  by  a  court of competent jurisdiction, the invalidity, illegality or
unenforceability shall not affect any other provision hereof (or the remaining
portion  thereof) or the application of that provision to any other Persons or
circumstances.

     9.10          GOVERNING  LAW.    This  Agreement shall be governed by and
construed  in  accordance  with  the  internal  laws  of the State of Colorado
applicable  to  agreements made and to be performed entirely within that State
without  regard  to  the  conflicts  of  law  principles  of  that  State.

     9.11         COUNTERPARTS.  This Agreement may be executed in one or more
counterparts, all of which shall be considered one and the same agreement, and
shall  become effective when one or more counterparts have been signed by each
of  the  parties  and  delivered  to  the  other  party.


     IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of
the  date    first  above  written.



     INTERNATIONAL  NURSING  SERVICES,  INC.

     By:/s/  John  P.  Yeros
     John  P.  Yeros,
     Chairman  and  Chief  Executive  Officer




     CYMEDIX  LYNX  CORPORATION

     By:/s/  John  P.  Yeros
     John  P.  Yeros,
     Chairman  and  Chief  Executive  Officer



     CYMEDIX  CORPORATION

     By:/s/  Keith  Berman
     Keith  Berman,  President

<PAGE>







                             AMENDMENT  NO. 1 TO
                         AGREEMENT AND PLAN OF MERGER

     This  Amendment  No.  1  to  the Agreement and Plan of Merger dated as of
November  17,  1997  (the  "Merger  Agreement")  among  International  Nursing
Services,  Inc.,  a Colorado corporation (collectively, with its subsidiaries,
the  "Company"), Cymedix Lynx Corporation, a Colorado corporation wholly owned
by  the  Company  (the  "Merger  Sub")  and  Cymedix Corporation, a California
corporation  ("Cymedix")  is  entered  into  as of December 10, 1997 among the
parties  to  the  Merger  Agreement.

     In  accordance  with  Section  8.1  of  the Merger Agreement, the parties
desire  to amend the Merger Agreement to delete Section 6.10(c) thereof in its
entirety  and  replace  it  with  the  following:

     "(c)  By acceptance of Merger Shares, each Holder will be deemed to agree
to  (i)  refrain  from publicly selling or offering for sale any Merger Shares
until the Registration Statement is effective, (ii) refrain from effecting any
disposition  of  Merger Shares that would constitute a sale within the meaning
of the Securities Art except as contemplated in the Registration Statement and
(iii)  limit  sales  in each month during the period from the effectiveness of
the  Registration  Statement until the first anniversary of the Effective Date
to  10  %  of  the  Merger  Shares received by that Holder in the Merger.  The
Company  will be entitled to place stop orders with the transfer agent for the
Company  Common  Stock  to  implement  the  restriction."

     As  amended hereby, the Merger Agreement shall continue in full force and
effect.  This Amendment No. 1 may be executed in separate counterparts, all of
which  shall  be  considered  one  and  the  same  instrument and shall become
effective  when  one  or  more  counterparts  have  been signed by each of the
parties  and  delivered  to  the  other  party.

     IN WITNESS WHEREOF, the parties hereto have executed this Amendment No. 1
as  of  the  date  first  above  written.
                                      INTERNATIONAL NURSING  SERVICES,  INC.
                                       By:  /s/John  P.  Yeros
                                            Chairman  and  Chief  Executive  
                                            Officer

                                       CYMEDIX  LYNX  CORPORATION
                                       By:  /s/  John  P.  Yeros
                                       Chairman  and  Chief  Executive  Officer

                                       CYMEDIX CORPORATION
                                       By: /s/ Keith  Berman
                                           President








INTERNATIONAL
NURSING
SERVICES, INC.
- --------------

COMPANY CONTACT:                         INVESTOR RELATIONS:
John P. Yeros                            Keith L. Lippert ([email protected])
International Nursing Services, Inc.     Bruce Voss ([email protected])
(303) 393-1515                           Sue Yeoh ([email protected])
                                         Lippert/Heilshorn & Associates, Inc.
                                         (212)     838-3777

FOR IMMEDIATE RELEASE


INTERNATIONAL NURSING SERVICES ANNOUNCES APPROVAL OF ACQUISITIONS OF CYMEDIX
CORPORATION AND LAUNCH OF CYMEDIX LYNX INTERNET MEDICAL SERVICE

DENVER  (DECEMBER  22,  1997) - INTERNATIONAL NURSING SERVICES, INC. (NASDAQ):
NURS)    today announced that the company's acquisition of Cymedix Corporation
has  been  approved  by Cymedix Corporation's shareholders, and is expected to
close  in early January 1998.  The company will acquire privately held Cymedix
Corporation  for  approximately  seven million shares of International Nursing
Services common stock, bringing the total number of shares outstanding to 19.7
million.  Cymedix Corporation will be operated as a wholly owned subsidiary of
International  Nursing  Services  under  the  name  Cymedix  Lynx.

Cymedix  Corporation  developed  the Internet-based medical communications and
information  management  product  Cymedix  Lynx,  which the company will begin
marketing  to  medical  professionals  nationwide  in  January.  Keith Berman,
president  and  found  of  Cymedix,  has  joined  Internal Nursing Services as
President  of  the  Cymedix Lynx subsidiary, and will report to John P. Yeros,
chairman.

"The  acquisition  of  Cymedix  Corporation  is  a  significant  event  in the
company's  history  and  greatly  expands  our  operations,"  said Yeros.  "We
believe  that  Cymedix  Lynx  holds  tremendous revenue opportunity and offers
potential  synergies  with  our  core  supplemental  staffing  business.    A
comprehensive  marketing  plan  is in place, and we are eager to begin selling
Cymedix  Lynx."

"We recently participated in the National Managed Health Care Fall Congress in
Los  Angeles where there was a tremendous interest in Cymedix Lynx," he added.
"Negotiations  are  underway  with  a  state agency in the Midwest, an Eastern
university  medical  school  and  hospital,  a  large  publicly  held  HMO  in
California,  a traditional indemnity health insurance company headquartered on
the  East  Cost,  as well as another in the Midwest.  We are encouraged by the
positive  response  we  have  received  to date and look forward to presenting
Cymedix  Lynx  to  a  wider  audience  of  health  care  professionals."

Growth  of  the  medical information management marketplace is being driven by
the  need  to  share  significant  amounts  of clinical and patent information
between  physicians,  their outpatient service providers, hospitals, insurance
companies  and  managed  care  organizations.    This  market  is  one  of the
fastest-growing sectors in healthcare today, commanding a projected two-thirds
of  health  care  capital  investments.

Cymedix Lynx is a secure, a patented medical communications product that makes
use  of  the  Internet.   Using Cymedix Lynx, medical professionals can order,
prescribe  and access medical information from insurance companies and managed
care  organizations,  as  well  as  from  any participating outpatient service
provider  such  as  a laboratory, radiology center, pharmacy or hospital.  The
company  will  provide  its software free of charge to physicians and clinics,
and  will  collect  user fees whenever these products connect to the Internet.

The  product's  relational  database  technology  provides  physicians  with a
permanent,  ongoing  record  of  each  patient's  name,  address, insurance or
managed care affiliation, referral status, medical history, personalized notes
and  an  audit  trail of past encounters.  Physicians can electronically order
medical procedures, receive and store test results, check patient eligibility,
make  medical  referrals,  request  authorizations,  and  report financial and
encounter  information  in  a  cost-effective,  secure  and  timely  manner.
Reference  is  made  to  a  concurrent Form 8-K filing with the Securities and
Exchange  Commission,  which contains additional information about the Cymedix
acquisition.

International  Nursing  Services  provide  skilled nursing, rehabilitation and
other  medical  personnel  for  flexible  staffing in home care and in a broad
spectrum  of  health  care and educational facilities.  The company's staffing
services  are provided through a diverse pool of caregivers including licensed
and  registered  nurses,  physical,  occupational  and respiratory therapists,
speech  and language pathologists, medical social workers, home care aides and
other  unlicensed  personnel.   The company has offices in Denver, Houston and
San  Antonio,  Tex.,  and  Emeryville  and  Ontario,  Calif.

                                      ***

"Safe  Harbor" Statement under the Private Securities Litigation Reform Act of
1995:  The statements contained in this release which are not historical facts
contain  forward-looking  information  with  respect to the plans, projections
and/or  future  performance  of  the  company, the occurrence of which involve
certain  risks  and  uncertainties  detailed in the company's filings with the
Securities and Exchange Commission.  Reference is made to the Quarterly Report
on  form  10-QSB  filed  with  the  SEC  on  November  14,  1997.






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