VAN KAMPEN SERIES FUND INC
497, 1999-01-28
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                    SUPPLEMENT DATED JANUARY 28, 1999 TO THE
 
                      STATEMENT OF ADDITIONAL INFORMATION
 
                            DATED SEPTEMBER 30, 1998
 
                         VAN KAMPEN AMERICAN VALUE FUND
 
                                PORTFOLIO OF THE
 
                  VAN KAMPEN SERIES FUND, INC. (THE "COMPANY")
                  P.O. BOX 418256 KANSAS CITY, MISSOURI 64141
 
                                 -------------
 
THE SECTION IN THE STATEMENT OF ADDITIONAL INFORMATION ENTITLED "PURCHASE OF
SHARES" IS SUPPLEMENTED WITH THE FOLLOWING:
 
    In order to facilitate the management of Van Kampen American Value Fund's
portfolio, effective August 31, 1998, the Fund suspended the continuous offering
of its shares to new investors. However, existing shareholders as of August 31,
1998 may continue to purchase additional shares, as well as those in Merrill
Lynch MFA Selects wrap-fee distribution programs and retirement plans held or
administered by Merrill Lynch, Van Kampen Trust Company or Morgan Stanley Dean
Witter & Co. or its affiliates. As market conditions permit, the Fund may reopen
sales of the Fund's shares to new investors. Any such offerings of the Fund may
be limited in amount and may commence and terminate without any prior notice.
 
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               PLEASE RETAIN THIS SUPPLEMENT FOR FUTURE REFERENCE


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