<PAGE> 1
SUPPLEMENT DATED JANUARY 11, 2000 TO THE
STATEMENT OF ADDITIONAL INFORMATION DATED OCTOBER 28, 1999
VAN KAMPEN SERIES FUND, INC. ON BEHALF OF ITS SERIES:
VAN KAMPEN AMERICAN VALUE FUND
VAN KAMPEN ASIAN GROWTH FUND
VAN KAMPEN EMERGING MARKETS FUND
VAN KAMPEN EMERGING MARKETS DEBT FUND
VAN KAMPEN EQUITY GROWTH FUND
VAN KAMPEN EUROPEAN EQUITY FUND
VAN KAMPEN FOCUS EQUITY FUND
VAN KAMPEN GLOBAL EQUITY FUND
VAN KAMPEN GLOBAL EQUITY ALLOCATION FUND
VAN KAMPEN GLOBAL FIXED INCOME FUND
VAN KAMPEN GLOBAL FRANCHISE FUND
VAN KAMPEN GROWTH AND INCOME FUND II
VAN KAMPEN HIGH YIELD & TOTAL RETURN FUND
VAN KAMPEN INTERNATIONAL MAGNUM FUND
VAN KAMPEN JAPANESE EQUITY FUND
VAN KAMPEN LATIN AMERICAN FUND
VAN KAMPEN MID CAP GROWTH FUND
VAN KAMPEN VALUE FUND
VAN KAMPEN WORLDWIDE HIGH INCOME FUND
The section of the Statement of Additional Information entitled DIRECTORS
AND OFFICERS is hereby supplemented by deleting Richard M. DeMartini's and Don
G.
<PAGE> 2
Powell's biographies and adding Mitchell M. Merin's and Richard F. Powers, III's
biographies, as set forth below, effective December 15, 1999.
<TABLE>
<CAPTION>
Principal Occupations or
Name, Address and Age Employment in Past 5 Years
--------------------- --------------------------
<S> <C>
Mitchell M. Merin*........................ President and Chief Operating
Two World Trade Center Officer of Asset Management of
66th Floor Morgan Stanley Dean Witter
New York, NY 10048 since December 1998. President
Date of Birth: 08/13/53 and Director since April 1997
and Chief Executive Officer
since June 1998 of Morgan
Stanley Dean Witter Advisors
Inc. and Morgan Stanley Dean
Witter Services Company Inc.
Chairman, Chief Executive
Officer and Director of Morgan
Stanley Dean Witter
Distributors Inc. since June
1998. Chairman and Chief
Executive Officer since June
1998, and Director since
January 1998, of Morgan Stanley
Dean Witter Trust FSB. Director
of various Morgan Stanley Dean
Witter subsidiaries. President
of the Morgan Stanley Dean
Witter Funds and Discover
Brokerage Index Series since
May 1999. Trustee/Director of
each of the funds in the Fund
Complex, and Vice President of
other investment companies
advised by the Advisers and
their affiliates. Previously
Chief Strategic Officer of
Morgan Stanley Dean Witter
Advisors Inc. and Morgan
Stanley Dean Witter Services
Company Inc. and Executive Vice
President of Morgan Stanley
Dean Witter Distributors Inc.
April 1997-June 1998, Vice
President of the Morgan Stanley
Dean Witter Funds and Discover
Brokerage Index Series May
1997-April 1999, and Executive
Vice President of Dean Witter,
Discover & Co.
</TABLE>
<PAGE> 3
<TABLE>
<CAPTION>
Principal Occupations or
Name, Address and Age Employment in Past 5 Years
--------------------- --------------------------
<S> <C>
Richard F. Powers, III*................... Chairman, President and Chief
1 Parkview Plaza Executive Officer of Van Kampen
P.O. Box 5555 Investments. Chairman, Director
Oakbrook Terrace, IL 60181-5555 and Chief Executive Officer of
Date of Birth: 02/02/46 the Advisers, the Distributor,
Van Kampen Advisors Inc. and
Van Kampen Management Inc.
Director and officer of certain
other subsidiaries of Van
Kampen Investments.
Trustee/Director and President
of each of the funds in the
Fund Complex. Trustee,
President and Chairman of the
Board of other investment
companies advised by the
Advisers and their affiliates,
and Chief Executive Officer of
Van Kampen Exchange Fund. Prior
to May 1998, Executive Vice
President and Director of
Marketing at Morgan Stanley
Dean Witter and Director of
Dean Witter Discover & Co. and
Dean Witter Realty. Prior to
1996, Director of Dean Witter
Reynolds Inc.
</TABLE>
The footnote immediately following the biographies of the directors is
hereby deleted and replaced in its entirety by the following:
* Such director is an "interested person" (within the meaning of Section
2(a)(19) of the 1940 Act). Mr. Whalen is an interested person of each of the
Funds in the Fund Complex by reason of his firm currently acting as legal
counsel to each of the Funds in the Fund Complex. Messrs. Merin and Powers are
interested persons of each of the Funds in the Fund Complex and the Advisers by
reason of their positions with Morgan Stanley Dean Witter or its affiliates.
