VAN KAMPEN SERIES FUND INC
NSAR-B, EX-99, 2000-08-29
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REPORT OF INDEPENDENT AUDITORS

To the Board of Directors and Shareholders of
Van Kampen Series Fund, Inc.

In planning and performing our audits of the financial
 statements of Van Kampen Series Fund, Inc., which
includes the American Value Fund, Asian Growth Fund,
Emerging Markets Fund, Equity Growth Fund, European Equity
Fund, Focus Equity Fund, Global Equity Allocation Fund,
Global Equity Fund, High Yield & Total Return Fund,
International Magnum Fund, Latin American Fund, Mid Cap
Growth Fund, Tax Managed Global Franchise Fund, Value Fund,
and Worldwide High Income Fund (collectively, the Funds)
for the year ended June 30, 2000 (on which we have issued
our reports dated August 11, 2000), we considered their
internal control, including control activities for
safeguarding securities, in order to determine our auditing
procedures for the purpose of expressing our opinion on the
financial statements and to comply with the requirements of
Form N-SAR, and not to provide assurance on the Funds'
internal control.

The management of the Funds is responsible for establishing
 and maintaining internal control.  In fulfilling this
responsibility, estimates and judgments by management are
required to assess the expected benefits and related costs
of controls.  Generally, controls that are relevant to an
audit pertain to the entity's objective of preparing
financial statements for external purposes that are fairly
presented in conformity with accounting principles generally
accepted in the United States of America.  Those controls
include the safeguarding of assets against unauthorized
acquisition, use, or disposition.

Because of inherent limitations in any internal control,
misstatements due to error or fraud may occur and not be
detected.  Also, projections of any evaluation of internal
control to future periods are subject to the risk that the
internal control may become inadequate because of changes
in conditions, or that the degree of compliance with
policies or procedures may deteriorate.

Our consideration of the Funds' internal control would not
necessarily disclose all matters in the internal control
that might be material weaknesses under standards established
by the American Institute of Certified Public Accountants.
A material weakness is a condition in which the design or
operation of one or more of the internal control components
does not reduce to a relatively low level the risk that
misstatements caused by error or fraud in amounts that would
be material in relation to the financial statements being
audited may occur and not be detected within a timely period
by employees in the normal course of performing their assigned
functions.  However, we noted no matters involving the Funds'
internal control and its operation, including controls for
afeguarding securities, that we consider to be material
weaknesses as defined above as of June 30, 2000.

This report is intended solely for the information and use of the Funds'
management, the Board of Directors and Shareholders of Van Kampen Series
Fund, Inc., and the Securities and Exchange Commission and is not intended
to be and should not be used by anyone other than these specified parties.


August 11, 2000



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