VAN KAMPEN SERIES FUND INC
497J, 2000-10-31
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                                                                          497(j)
                                October 31, 2000


Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

     Re:  Van Kampen Series Fund, Inc. -- Rule 497(j) Filing
          (Filing Nos. 033-51294 and 811-7140)

Ladies and Gentlemen:

         Van Kampen Series Fund, Inc. (the "Registrant") filed via EDGAR on
October 27, 2000 a copy of Post-Effective Amendment No. 30 to the Registration
Statement on Form N-1A (the "Registration Statement") complete with exhibits
filed therewith pursuant to Rule 485(b) of the General Rules and Regulations
(the "1933 Act Rules") of the Securities and Exchange Commission promulgated
under the Securities Act of 1933, as amended, and under the Investment Company
Act of 1940, as amended.

         In accordance with the provisions of Rule 497(j) of the 1933 Act
Rules this letter serves to certify that the prospectuses contained therein,
with the exception of the prospectus for the Van Kampen European Equity Fund,
and statement of additional information contained therein do not differ from
that which would have been filed pursuant to Rule 497 (c) of the 1933 Act
Rules. The prospectus for the Van Kampen European Equity Fund is being
filed under separate cover pursuant to Rule 497 (c).

         Should the staff have any questions regarding the foregoing, please
contact me at (630) 684-8370.

                                               Very Truly yours,

                                               /s/ Sara L. Badler
                                               -------------------


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