CYPROS PHARMACEUTICAL CORP
SC 13G, 1999-02-16
PHARMACEUTICAL PREPARATIONS
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                          UNITED STATES
               SECURITIES AND EXCHANGE COMMISSION
                     WASHINGTON, D.C. 20549
                                
                          SCHEDULE 13G
                                
            Under the Securities Exchange Act of 1934
                                
                                
                                
                CYPROS PHARMACEUTICAL CORPORATION
                        (Name of Issuer)
                                
                          Common Stock
                 (Title of Class of Securities)
                                
                            232808105
                         (CUSIP Number)
                                
                        December 31, 1998
     (Date of Event Which Requires Filing of This Statement)
                                
          Check the appropriate box to designate the rule
pursuant to which this Schedule is filed:

          [x]   Rule 13d-1(b)

          [x]   Rule 13d-1(c)

          [x]   Rule 13d-1(d)


          *The remainder of this cover page shall be filled out
for a reporting person's initial filing on this form with respect
to the subject class of securities, and for any subsequent
amendment containing information which would alter the
disclosures provided in a prior cover page.

          The information required in the remainder of this cover
page shall not be deemed to be "filed" for the purpose of Section
18 of the Securities Exchange Act of 1934 ("Act") or otherwise
subject to the liabilities of that section of the Act but shall
be subject to all other provisions of the Act (however, see the
Notes).
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CUSIP 232808105            SCHEDULE 13G                Page 2 of 7


  1     Name Of Reporting Person            WENTWORTH, HAUSER & VIOLICH
        
        IRS Identification No. Of Above Person

  2     Check The Appropriate Box If A Member Of A Group       (a)  [ ]
        N/A
                                                               (b)  [ ]
  3     SEC USE ONLY
        
  4     Citizenship Or Place Of Organization
        
                         California, United States

                        5    Sole Voting Power
  NUMBER OF                  
    SHARES                          957,705
 BENEFICIALLY
OWNED BY EACH
  REPORTING
 PERSON WITH
                        6    Shared Voting Power
                             
                                      -0-

                        7    Sole Dispositive Power
                             
                                    957,705

                        8    Shared Dispositive Power
                             
                                      -0-

    9      Aggregate Amount Beneficially Owned By Each Reporting Person
           
                                    957,705

   10      Check Box If The Aggregate Amount In Row (9) Excludes Certain
           Shares*
           
   11      Percent Of Class Represented By Amount In Row 9
           
                                      6.1%

   12      Type Of Reporting Person*
           
                                       IA
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CUSIP 232808105            SCHEDULE 13G                Page 3 of 7


  1     Name Of Reporting Person  LAIRD NORTON TRUST COMPANY OF SEATTLE
        
        IRS Identification No. Of Above Person

  2     Check The Appropriate Box If A Member Of A Group       (a)  [ ]
        N/A
                                                               (b)  [ ]
  3     SEC USE ONLY
        
        
  4     Citizenship Or Place Of Organization
        
                         Washington, United States

                        5    Sole Voting Power
  NUMBER OF                  
    SHARES                            -0-
 BENEFICIALLY
OWNED BY EACH
  REPORTING
 PERSON WITH
                        6    Shared Voting Power
                             
                                    957,705

                        7    Sole Dispositive Power
                             
                                      -0-

                        8    Shared Dispositive Power
                             
                                      -0-

    9      Aggregate Amount Beneficially Owned By Each Reporting Person
           
                                    957,705

   10      Check Box If The Aggregate Amount In Row (9) Excludes Certain
           Shares*
           
   11      Percent Of Class Represented By Amount In Row 9
           
                                      6.1%

   12      Type Of Reporting Person*
           
                                       OO
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CUSIP 232808105            SCHEDULE 13G                Page 4 of 7


Item 1(a).  Name of Issuer.

            Cypros Pharmaceutical Corporation

Item 1(b).  Address of Issuer's Principal Executive Offices.
          
            2714 Loker Avenue
            Carlsbad, CA  92008
  
Item 2(a).  Names of Persons Filing.
          
            Wentworth, Hauser & Violich ("Wentworth").
          
            Laird Norton Trust Company of Seattle ("LNTC")
          
Item 2(b).  Address of Principal Business Office or, if none,
            Residence.
           
            The Address of Wentworth is:
            333 Sacramento Street
            San Francisco, CA  94111
          
            The Address of LNTC is:
          
            Laird Norton Trust Company
            801 Second Ave., Suite 1600
            Seattle, WA  98104
          
Item 2(c).  Citizenship.
          
            United States.
          
Item 2(d).  Title of Class of Securities.

            Common Stock.
  
Item 2(e).  CUSIP Number.
          
            232808105

Item 3.     Type of Reporting Person.
          
            Wentworth is an Investment Adviser registered under
Section 203 of the Investment Advisers Act of 1940 and a wholly
owned subsidiary of LNTC.

Item 4.     Ownership.

            Reference is hereby made to Items 5-9 and 11 of page
two (2) of this Amendment to Schedule 13G, which Items are
incorporated by reference herein.
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CUSIP 232808105            SCHEDULE 13G                Page 5 of 7


            Because Wentworth is a wholly owned subsidiary of
LNTC, it is possible that LNTC may be deemed a beneficial owner
of the Company's shares held by Wentworth by virtue the
definition of "Beneficail Ownership" in Rule 13d-3 under the
Securities Exchange Act of 1934.  Although Wentworth and LNTC are
reporting such securities as if they were members of a group, the
filing of this Schedule shall not be construed as an admission by
LNTC that it is a beneficial owner of any securities of the
Company held by Wentworth.

            In addition, it is possible that the individual
general partners, directors, executive officers, members, and/or
managers of Wentworth or LNTC might be deemed the "beneficial
owners" of some or all of the securities to which this Schedule
relates in that they might be deemed to share the power to direct
the voting or disposition of such securities.  Neither the filing
of this Schedule nor any of its contents shall be deemed to
constitute an admission that any of such individuals is, for any
purpose, the beneficial owner of any of the securities to which
this Schedule relates, and such beneficial ownership is expressly
disclaimed.

Item 5.     Ownership of Five Percent or Less of a Class.

            Not applicable.
  
Item 6.     Ownership of More Than Five Percent on Behalf of
            Another Person.
           
            Wentworth is deemed to be the beneficial owner of the
number of securities reflected in Items 5-9 and 11 of page two
(2) of this Amendment to Schedule 13G pursuant to separate
arrangements whereby Wentworth acts as investment adviser to
certain persons.  Each person for whom the reporting person acts
as investment adviser has the right to receive or the power to
direct the receipt of dividends from, or the proceeds from the
sale of, the Common Stock purchased or held pursuant to such
arrangements.

Item 7.     Identification and Classification of the Subsidiary
            Which Acquired the Security Being Reported on by the
            Parent Holding Company.
          
            Not applicable.

Item 8.     Identification and Classification of Members of the
            Group.
           
            Not applicable.

Item 9.     Notice of Dissolution of Group.
          
            Not applicable.
<PAGE>
CUSIP 232808105            SCHEDULE 13G                Page 6 of 7


Item 10.    Certification.
          
            By signing below, the undersigned certifies that, to
the best of his knowledge and belief, the securities referred to
above were acquired and are held in the ordinary course of
business and were not acquired and are not held for the purpose
of or with the effect of changing or influencing the control of
the issuer of the securities and were not acquired and are not
held in connection with or as a participant in any transaction
having that purpose or effect.
                                
                                
                            Signature
                                
          After reasonable inquiry and to the best of my
knowledge and belief, the undersigned certifies that the
information set forth in this statement is true, complete and
correct.


                           WENTWORTH  HAUSER & VOILICH
                           
                           
                           
                           By: /s/ Bradford Hall
                               _________________________
                           Title:  Vice President

DATED:  February 16, 1999
<PAGE>
CUSIP 232808105            SCHEDULE 13G                Page 7 of 7


                            Signature
                                
          After reasonable inquiry and to the best of my
knowledge and belief, the undersigned certifies that the
information set forth in this statement is true, complete and
correct.


                         LAIRD NORTON TRUST COMPANY OF SEATTLE
                         
                         
                         
                         By: /s/ Steven A. Rhone
                             __________________________________
                             Steven A. Rhone, Executive Vice
                             President
                             
DATED:  February 16, 1999



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