CELL THERAPEUTICS INC
3, 2000-02-11
PHARMACEUTICAL PREPARATIONS
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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                     FORM 3

             INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

     Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
       Section 17(a) of the Public Utility Holding Company Act of 1935 or
               Section 30(f) of the Investment Company Act of 1940

- --------------------------------------------------------------------------------
1. Name and Address of Reporting Person*

Rosenwald, M.D.,        Lindsay                 A.
- --------------------------------------------------------------------------------
   (Last)               (First)                 (Middle)

787 Seventh Avenue, 48th Floor
- --------------------------------------------------------------------------------
                                    (Street)

New York,             New York                   10019
- --------------------------------------------------------------------------------
   (City)               (State)                 (Zip)

- --------------------------------------------------------------------------------
2. Date of Event Requiring Statement (Month/Day/Year)

January 10, 2000
- --------------------------------------------------------------------------------
3. IRS Identification Number of Reporting Person, if an entity (Voluntary)

- --------------------------------------------------------------------------------
4. Issuer Name and Ticker or Trading Symbol

Cell Therapeutics, Inc. (CTIC)
- --------------------------------------------------------------------------------
5. Relationship of Reporting Person to Issuer
   (Check all applicable)

|_|   Director                             |X|   10% Owner
|_|   Officer (give title below)           |_|   Other (specify below)

- --------------------------------------------------------------------------------
6. If Amendment, Date of Original (Month/Day/Year)

- --------------------------------------------------------------------------------
7. Individual or Joint/Group Filing (Check applicable line)

   |_| Form filed by One Reporting Person

   |_| Form filed by More than One Reporting Person

================================================================================

- --------------------------------------------------------------------------------
             Table I -- Non-Derivative Securities Beneficially Owned
- --------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                 3. Ownership Form:
                                      2. Amount of Securities       Direct (D) or
1. Title of Security                     Beneficially Owned         Indirect (I)       4. Nature of Indirect Beneficial Ownership
   (Instr. 4)                            (Instr. 4)                 (Instr. 5)            (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
   <S>                                   <C>                         <C>
   Common Stock                          976,065                     D
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>

* If the Form is filed by more than one Reporting Person see instruction
5(b)(v).

Reminder: Report on a separate line for each class of securities beneficially
owned directly or indirectly.


                                  Page 1 of 3
<PAGE>

FORM 3 (continued)

     Table II - Derivative Securities Beneficially Owned (e.g., puts, calls,
                   warrants, options, convertible securities)
<TABLE>
<CAPTION>
- ------------------------------------------------------------------------------------------------------------------------------------

                                                    3. Title and Amount of Securities                 5. Ownership
                                                       Underlying Derivative Security                 Form of
                           2. Date Exercisable         (Instr. 4)                                     Derivative
                              and Expiration Date   ---------------------------------  4. Conver-     Security:
                              (Month/Day/Year)                             Amount      sion or        Direct        6. Nature of
                           ----------------------                          or          Exercise       (D) or        Indirect
                             Date       Expira-                            Number      Price of       Indirect      Beneficial
1. Title of Derivative       Exer-      tion                               of          Derivative     (I)           Ownership
   Security (Instr. 4)       cisable    Date        Title                  Shares      Security       (Instr. 5)    (Instr. 5)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                          <C>        <C>         <C>                    <C>           <C>          <C>            <C>
Series C Preferred Stock                            Common Stock           780,578                    I              By The Aries
                                                                                                                     Master Fund(1)
- ------------------------------------------------------------------------------------------------------------------------------------
Series C Preferred Stock                            Common Stock           316,301                    I              By Aries
                                                                                                                     Domestic Fund,
                                                                                                                     L.P.(1)
- ------------------------------------------------------------------------------------------------------------------------------------
Series C Preferred Stock                            Common Stock           24,509                     I              By Aries
                                                                                                                     Domestic Fund
                                                                                                                     II, L.P.(1)
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock Warrant      11/24/99      11/24/04    Common Stock           257,219       $2.625       I              By The Aries
                                                                                                                     Master Fund(1)
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock Warrant      11/24/99      11/24/04    Common Stock           104,229       $2.625       I              By Aries
                                                                                                                     Domestic Fund,
                                                                                                                     L.P.(1)
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock Warrant      11/24/99      11/24/04    Common Stock           8,076         $2.625       I              By Aries
                                                                                                                     Domestic Fund
                                                                                                                     II, L.P.(1)
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>

Explanation of Responses:

(1) See Attachment A and Attachment B


 /s/ Lindsay A. Rosenwald                   February 7, 2000
- -----------------------------------     ----------------------
**Lindsay A. Rosenwald, M.D.                       Date

**   Intentional misstatements or omissions of facts constitute Federal Criminal
     Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:  File three copies of this Form, one of which must be manually signed.
       If space provided is insufficient, See Instruction 6 for procedure.


                                  Page 2 of 3
<PAGE>

                                  ATTACHMENT A

Reporting Person: Lindsay A. Rosenwald, M.D.
Issuer:           Cell Therapeutics, Inc.

Paramount Capital Asset Management, Inc. ("PCAM") is the general partner of each
of the Aries Domestic Fund, L.P. ("Aries I") and Aries Domestic Fund II, L.P.
("Aries II"), each a Delaware limited partnership, and also serves as the
investment manager of the Aries Master Fund, a Cayman Island exempted company
(the "Master Fund"), which also owns securities of the Issuer. Dr. Rosenwald is
the chairman and sole stockholder of PCAM. As a result, Dr. Rosenwald and PCAM
may be deemed to have voting and investment control over the securities of the
issuer owned by the Aries Funds under Rule 16a-(a)(1) of the Securities Exchange
Act of 1934. Dr. Rosenwald and PCAM disclaim beneficial ownership of the
securities held by the Aries Funds, except to the extent of its pecuniary
interest therein, if any.


                                  Page 3 of 3


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