MARTEK BIOSCIENCES CORP
SC 13G, 1999-01-12
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                     SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                          ________________

                             240.13d-102
                                 SCHEDULE 13G

     INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO
(S)240.13D-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT
TO (S)240.13D-2

                             (Amendment No.    )*
                                           -----

                  MARTEK BIOSCIENCES CORPORATION
                  -------------------------------------------
                               (Name of Issuer)

                                 Common Stock
                  -------------------------------------------
                        (Title of Class of Securities)

                             572901106
                              ------------------
                                (CUSIP Number)

                         DECEMBER 31, 1998
          --------------------------------------------------------
- ---
               Date of Event Which Requires Filing of this
Statement)

Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:

          [X] Rule 13d-1(b)

          [_ Rule 13d-1(c)

          [_] Rule 13d-1(d)



*The remainder of this cover page shall be filled out for a
reporting person's
initial filing on this form with respect to the subject class of
securities, and
for any subsequent amendment containing information which would
alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall
not be deemed
to be "filed" for the purpose of Section 18 of the Securities
Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that
section of the Act
but shall be subject to all other provisions of the Act (however,
see the
Notes).






<PAGE>
- ------------------------
  CUSIP NO. 572901106                        13G
- ------------------------
- ------------------------------------------------------------------
- -------------
      NAME OF REPORTING PERSON
 1    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

      BankAmerica Corporation
- ------------------------------------------------------------------
- -------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2
(a) [_]

(b) [_]
- ------------------------------------------------------------------
- -------------
      SEC USE ONLY
 3
- ------------------------------------------------------------------
- -------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4    Delaware
- ------------------------------------------------------------------
- -------------
                          SOLE VOTING POWER
 5
     NUMBER OF            -0-

      SHARES       -----------------------------------------------
- ------------
 6                         SHARED VOTING POWER
   BENEFICIALLY
                    1,505,379
     OWNED BY
- -------------------------------------------------------

     EACH 7              SOLE DISPOSITIVE POWER

    REPORTING             -0-

      PERSON       -----------------------------------------------
- ------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                               1,505,379
- ------------------------------------------------------------------
- -------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9
         1,505,379
- ------------------------------------------------------------------
- -------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES*
10                                                          [_]
- ------------------------------------------------------------------
- -------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11
         10.12%
- ------------------------------------------------------------------
- -------------
      TYPE OF REPORTING PERSON*
12    HC
- ------------------------------------------------------------------
- -------------
                     *SEE INSTRUCTION BEFORE FILLING OUT!
                                     Page 2

<PAGE>

- ------------------------
  CUSIP NO.   572901106                      13G
- ------------------------
- ------------------------------------------------------------------
- -------------
      NAME OF REPORTING PERSON
 1    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

      NationsBank Holdings Corporation----------------------------
- -------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2
(a) [_]

(b) [_]
- ------------------------------------------------------------------
- -------------
      SEC USE ONLY
 3
- ------------------------------------------------------------------
- -------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4
      Charlotte NC------------------------------------------------
- --------------
                          SOLE VOTING POWER
 5
     NUMBER OF            -0-

      SHARES       -----------------------------------------------
- ------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                         1,505,379
     OWNED BY
                   -----------------------------------------------
- ------------
       EACH               SOLE DISPOSITIVE POWER
                     7
    REPORTING             -0-

      PERSON       -----------------------------------------------
- ------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                         1,505,379
- ------------------------------------------------------------------
- -------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9      1,505,379
- ------------------------------------------------------------------
- -------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES*
10                                                     [_]
- ------------------------------------------------------------------
- -------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11       10.12%
- ------------------------------------------------------------------
- -------------
      TYPE OF REPORTING PERSON*
12    HC
- ------------------------------------------------------------------
- -------------
                     *SEE INSTRUCTION BEFORE FILLING OUT!
                                     Page 3




<PAGE>
  ------------------------
  CUSIP NO. 572901106                        13G
- ------------------------
- ------------------------------------------------------------------
- -------------
      NAME OF REPORTING PERSON
 1    S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

      NationsBanc Capital Corporation
- ------------------------------------------------------------------
- -------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2
(a) [_]

(b) [_]
- ------------------------------------------------------------------
- -------------
      SEC USE ONLY
 3
- ------------------------------------------------------------------
- -------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4
      Charlotte NC------------------------------------------------
- --------------
                          SOLE VOTING POWER
                     5
     NUMBER OF            -0-

      SHARES       -----------------------------------------------
- ------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                            972,432
     OWNED BY
                   -----------------------------------------------
- ------------
       EACH               SOLE DISPOSITIVE POWER
                     7
    REPORTING             -0-

      PERSON       -----------------------------------------------
- ------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                           972,432
- ------------------------------------------------------------------
- -------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9        972,432
- ------------------------------------------------------------------
- -------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES*
10                                                [_]
- ------------------------------------------------------------------
- -------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11       6.54%
- ------------------------------------------------------------------
- -------------
      TYPE OF REPORTING PERSON*
12    IA
- ------------------------------------------------------------------
- -------------
                     *SEE INSTRUCTION BEFORE FILLING OUT!

                                     Page 4



<PAGE>

Item 1  (a)  Name of Issuer:  Martek Biosciences Corporation

        (b)  Address of Issuer's
             Principal Executive
           Offices:       6480 Dobbin rd.
                        Columbia, MD 21405


Item 2  (a)  Names of Person Filing:    BankAmerica (BAC)
                                   NB Holdings Corp
                                   NB Capital Corp.
        (b)  Address of Principal
           Business Offices:       BAC
                                   100 North Tryon St.
                                   Charlotte, NC 28255

                                   NB Holdings Corp.
                                   100 North Tryon St.
                                   Charlotte, NC 28255

                                   NB Capital Corp.
                                   100 North Tryon St.
                                   Charlotte, NC 28255

        (c)  Citizenship:               BAC            Delaware
                                   NB Holdings Corp. North
Carolina
                                   NB Capital Corp.    North
Carolina

        (d)  Title of Class of            Common Stock
             Securities:


        (e)  CUSIP Number: 572901106


Item 3       If this statement is filed pursuant to Rules 13d-1(b)
or 13d-2(b)
           or (c), check whether the person filing is a:

             (a) [_]   Broker or Dealer registered under Section
15 of the Act
                    (15 U.S.C. 78o)

             (b) [X]   Bank as defined in Section 3(a)(6) of the
Act (15 U.S.C.
                    78c)

             (c) [_]   Insurance Company as defined in Section
3(a)(19) of the
                       Act (15 U.S.C. 78c)

             (d) [_]   Investment Company registered under Section
8 of the
                       Investment Company Act (15 U.S.C. 80a-8)




                                     Page 7

<PAGE>


           (e) [_]   An investment adviser in accordance with
(S)240.13d-
                    1(b)(1)(ii)(E)

             (f) [_]   An employee benefit plan or endowment fund
in accordance
                    with (S)240.13d-1(b)(1)(ii)(F)

             (g) [_]   A parent holding company or control person
in accordance
                    with (S)240.13d-1(b)(ii)(G)

           (h) [_]   A savings association as defined in Section
3(b) of the
                    Federal Deposit Insurance Act (12 U.S.C. 1813)

           (i) [_]   A church plan that is excluded from the
definition of an
                    investment company under section 3(c)(14) of
the
                    Investment Company Act of 1940 (15 U.S.C. 80a-
3)

           (j) [_]   Group, in accordance with (S)240.13d-
1(b)(1)(ii)(J)


If this statement is filed pursuant to (S)240.13d-1(c), check this
box. [_



Item 4       *Ownership

             (a) Amount Beneficially Owned:
                     BAC                1,505,379
                     NB Holdings Corp.  1,505,379
                     NB Capital Corp.          972,432

           (b) Percent of Class:
                         BAC                        10.12%
                     NB Holdings Corp            10.12%
                     NB Capital Corp.             6.54%

___________
*    By virtue of the corporate relationships between Reporting
Persons as
     described in Item 7, BAC (the parent company) may be deemed
to possess
     indirect beneficial ownership of shares beneficially owned
directly by its
     subsidiaries. Similarly, higher tier BAC subsidiaries may be
deemed to      possess indirect beneficial ownership of shares
beneficially owned  directly by lower tier BAC subsidiaries. The
power to vote and to dispose  of shares may be deemed to be shared
between entities due to their      corporate relationships.

                              Page 8








<PAGE>
          (c) Number of shares as to which the person has:

                 (i)     sole power to vote or to direct the vote:
                        BAC                                      0
                     NB Holding Corp.                            0
                     NB Capital Corp.                       0

               (ii)    shared power to vote or to direct
                     the vote:
                     BAC                     10.12%
                     NB Holding Corp.             10.12%
NB Capital Corp.               6.54%

               (iii)   sole power to dispose or to direct the
                         disposition of:
                         BAC
0
                     NB Holding Corp.                            0
                     NB Capital Corp.                            0

                 (iv)    shared power to dispose or to direct
                     the disposition of:
                     BAC                     10.12%
                     NB Holding Corp.             10.12%
                     NB Capital Corp.              6.54%


Item 5       Ownership of Five Percent or Less of a Class.

             If this statement is being filed to report the fact
that as of the
             date hereof the reporting person has ceased to be the
beneficial
             owner of more than five percent of the class of
securities, check
             the following [_]








                                   Page 9















<PAGE>



Item 6       Ownership of More than Five Percent on Behalf of
Another Person.

             Not Applicable.


Item 7       Identification and Classification of the Subsidiaries
Which
             Acquired the Security Being Reported on by the Parent
Holding
             Company.

             See Annex I.


Item 8       Identification and Classification of Members of the
Group.

             Not Applicable.


Item 9       Notice of Dissolution of Group.

             Not Applicable.


Item 10     Certification.

[x]       By signing below I certify that, to the best of my
knowledge and
          belief, the securities referred to above were acquired
and are held
          in the ordinary course of business and were not acquired
and are             not held for the purpose of or with the effect
of changing or
          influencing the control of the issuer of the securities
and were            not acquired and are not held in connection
with or as a                  participant in any transaction
having that purpose or effect.               (13d-1(b)).

[_]       By signing below I certify that, to the best of my
knowledge and            belief, the securities referred to above
were not acquired and are          not held for the purpose of or
with the effect of changing or               influencing the
control of the issuer of the securities and were            not
acquired and are not held in connection with or as a
          participant in any transaction having that purpose or
effect.             (13d-1(c)).









                              Page 10



<PAGE>

SIGNATURE



- ----------

     After reasonable inquiry and to the best of my knowledge and
belief, the
undersigned certify that the information set forth in this
statement is true,
complete and correct.

Dated: January 11, 1999



     BANKAMERICA CORPORATION*

     NB HOLDINGS CORPORATION

     NB CAPITAL CORPORATION



*By: /s/ STEPHEN A DOYLE

     Stephen A Doyle
     Vice President
     Corporate Compliance



















                              Page 11








<PAGE>

                                   EXHIBIT A
                                   ---------

                             JOINT FILING AGREEMENT
                             ----------------------


     The undersigned hereby agree that they are filing this
statement jointly
pursuant to Rule 13d-1(f)(1).  Each of them is responsible for the
timely filing
of such Schedule 13G and any amendments thereto, and for the
completeness and
accuracy of the information concerning such person contained
therein; but none
of them is responsible for the completeness or accuracy of the
information
concerning the other persons making the filing, unless such person
knows or has
reason to believe that such information is inaccurate.

Date: January 11, 1999


     BANKAMERICA CORPORATION*

     NB HOLDINGS CORPORATION

     NB CAPITAL CORPORATION



*By: /s/ STEPHEN A DOYLE

     Stephen A Doyle
     Vice President
     Corporate Compliance


















                                     Page 12



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