DERMA SCIENCES INC
8-K, 1997-11-24
PHARMACEUTICAL PREPARATIONS
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________________________________________________________________________________


                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                 --------------


                                    FORM 8-K


                 CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934



       Date of Report (Date of earliest event reported): November 19, 1997




                              DERMA SCIENCES, INC.
             (Exact name of registrant as specified in its charter)





        Pennsylvania                   1-31070                 23-2328753
(State or other jurisdiction         (Commission              (IRS employer
     of incorporation)               File Number)         identification number)







                         214 Carnegie Center, Suite 100
                               Princeton, NJ 08540
                                 (609) 514-4744
                    (Address including zip code and telephone
                     number, of principal executive offices)






________________________________________________________________________________

<PAGE>


Item 5.  Other Events

      Derma  Sciences,  Inc.  (the  "Registrant")  on November 19, 1997 closed a
private placement of Convertible Debentures ("Debentures") in which an aggregate
of $1.8 million was raised.  Terms of the Debentures  require that upon approval
of  the  Registrant's  shareholders  of a new  class  of  Series  A  Convertible
Preferred Shares ("Preferred Stock"), the Debentures will automatically  convert
into units  ("Unit(s)"),  as hereafter  defined,  at the rate of $0.80 per Unit.
Each Unit will  consist of one share of  Preferred  Stock  convertible  into one
share of Common  Stock and one warrant  ("Warrant(s)")  to purchase one share of
Common  Stock  exercisable  $0.90 per  share.  The  Registrant  expects  to seek
shareholder approval for creation of the Preferred Stock at a special meeting of
shareholders which is anticipated to occur in late December, 1997.

      Purchasers in the offering included San Francisco-headquartered  Hambrecht
& Quist, New York City-based Galen Associates, the Aries Funds and Redwood Asset
Management,  as well as certain of the  Registrant's  executives and associates.
Proceeds  from the  private  placement  will be used to expand the  Registrant's
sales force and to enhance its marketing and distribution efforts.

      The Debentures have not been  registered  under the Securities Act of 1933
(the  "Act")  and  may be  offered  or  sold  in the  United  States  only  upon
registration or pursuant to an exemption from  registration.  The Registrant has
undertaken,  not later than 120 days following closing of its private placement,
to file a  registration  statement  under the Act to permit resale of the Common
Stock issuable upon  conversion of the Preferred  Stock and upon exercise of the
Warrants.

      The terms and  conditions  governing the offer and sale of the  Debentures
are  contained  in the form of  Purchase  Agreement  attached  hereto as exhibit
10.01. The obligations of the Registrant with respect to the registration  under
the Act of its Common Stock issuable upon  conversion of the Preferred Stock and
upon exercise of the Warrants are described in the form of  Registration  Rights
Agreement  attached  hereto as exhibit 10.02.  The rights and preferences of the
Preferred  Stock  which,  together  with the  Warrants,  comprise  the Units are
described in the form of Certificate of Designations, Voting Powers, Preferences
and  Rights of the  Series A  Convertible  Preferred  Stock  attached  hereto as
exhibit 10.03. Terms governing the issuance and exercise of the Warrants are set
forth in the form of Warrant Agreement  attached hereto as exhibit 10.04.  Terms
governing the rights and  responsibilities  of the holders of the Debentures are
set forth in the form of Convertible Debenture attached hereto as exhibit 10.05.

      The Registrant on November 24, 1997 accepted the offer of investors owning
$400,000  aggregate  principal  amount of Debentures to convert these Debentures
directly  into  Common  Stock  and  Warrants  in like  manner  as if:  (1) these
Debentures had been converted into Units, and (2) the Preferred Stock comprising
the Units had been converted into Common Stock. The effect of this conversion is
to transfer,  as of November 24, 1997,  $400,000 from the  Registrant's  debt to
capital and capital surplus thereby  increasing the  Registrant's  shareholders'
equity from $805,194 to $1,205,194.

       The  following  table sets forth under the heading  "Actual" the  current
debt and equity capitalization of the Company derived by adjusting the Company's
debt and equity  capitalization  at  September  30,  1997 (as  reflected  in the
Company's  Quarterly  Report on Form 10-QSB for the quarter ended  September 30,
1997) to give effect to: (a) the November 19, 1997 sale of $1,800,000  aggregate


                                        2
<PAGE>

principal  amount of  Debentures,  and (b) the November 24, 1997  conversion  of
$400,000 aggregate  principal amount of Debentures into 500,000 shares of Common
Stock and 500,000  Warrants to  purchase  one share of Common  Stock at $.90 per
share.  The table sets forth under the heading "As Adjusted" the debt and equity
capitalization  of  the  Company  adjusted  to  give  effect  to  the  mandatory
conversion of the remaining  $1,400,000 aggregate principal amount of Debentures
into 1.75 million Units.


                              DERMA SCIENCES, INC.

                                 CAPITALIZATION

<TABLE>
<CAPTION>

                                                            Actual         As Adjusted
                                                       ---------------   ---------------
<S>                                                       <C>           <C>
Current Liabilities:

    Accounts Payable ..................................   $   679,931    $   679,931
    Other current liabilities .........................       543,121        543,121

Debentures and Notes Payable:

    Convertible debentures ............................     1,400,000              0
    Bank line of credit ...............................       789,000        789,000
    Other notes payable ...............................        95,000         95,000
                                                          ------------   ------------

Total debt ............................................   $ 3,507,052    $ 2,107,052

Shareholders' Equity

    Common Stock, $.01 par value, 15,000,000 shares
      authorized, 4,067,632 shares issued and
      outstanding (*) .................................   $    45,676    $    45,676
    Series A Preferred Stock, $.01 par value, 1,750,000
      shares to be authorized, issued and outstanding .             0         17,500
    Additional paid-in capital, common stock ..........     5,039,741      5,039,741
    Additional paid-in capital, preferred stock .......             0      1,382,500
    Accumulated deficit ...............................    (3,880,223)    (3,880,223)
                                                          ------------   ------------

Total shareholders' equity ............................   $ 1,205,194    $ 2,605,194
                                                          -----------    ------------

Total capitalization ..................................   $ 4,712,246    $ 4,712,246

</TABLE>

- -------------
(*)  Excludes:  (i)  shares of Common  Stock  subject to  currently  outstanding
options;  (ii)  conversion of Series A Preferred  Stock into Common  Stock;  and
(iii) exercise of Warrants to purchase Common Stock.



                                       3

<PAGE>


      The Registrant's Board of Directors has approved the recommendation of its
Compensation  Committee  that  Edward  J.  Quilty,  Chairman  of  the  Board  of
Directors,  be granted incentive stock options to purchase 100,000 shares of the
Registrant's Common Stock at a price of $0.80 per share in partial consideration
for the  Chairman's  efforts in effecting  the  foregoing  private  placement of
Debentures.  These options become exercisable to the extent of 50%, 75% and 100%
on May 19, 1998, May 19, 1999 and November 19, 1999, respectively.

Item 7.  Financial Statements and Exhibits

         (a)  Not applicable

         (b)  Not applicable

         (c)    Exhibits:

                    Number    Description
                    ------    -----------
                    10.01     Form of Purchase Agreement.

                    10.02     Form of Registration Rights Agreement.

                    10.03     Form of Certificate of Designations, Voting 
                              Powers,  Preferences  and Rights of the Series A
                              Convertible Preferred Stock.

                   10.04      Form of Warrant Agreement

                   10.05      Form of Convertible Debenture
















                                       4
<PAGE>



         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.


                                            DERMA SCIENCES, INC.



Date:  November 24, 1997                    By:/s/  Edward J. Quilty
                                               ---------------------
                                               Edward J. Quilty
                                               Chairman



















                                       5







                               PURCHASE AGREEMENT

                  THIS PURCHASE  AGREEMENT (this  "Agreement") is made as of the
___ day of November  1997,  by and between Derma  Sciences,  Inc., a corporation
organized under the laws of the  Commonwealth of Pennsylvania  (the  "Company"),
with its principal  offices at 214 Carnegie Center,  Suite 100,  Princeton,  New
Jersey  08540,  and the  purchaser  whose  name and  address is set forth on the
signature page hereof (the "Purchaser").

                  IN  CONSIDERATION  of the mutual  covenants  contained in this
Agreement, the Company and the Purchaser agree as follows:

                  SECTION  1.  Designation  and  Authorization  of  Sale  of the
Debentures and Units. Subject to the terms and conditions of this Agreement, the
Company has authorized the sale of up to $1,800,000  aggregate  principal amount
of the  Company's  Convertible  Debentures  due  1998  (the  "Debentures").  The
Debentures  will bear interest on, and subject to, the terms  described  therein
beginning  on the 120th day from the date hereof if the Company has not obtained
authorization for the issuance of the Preferred Shares.  The Debentures shall be
convertible  on or after the  Authorization  Date (as defined  herein) into such
number of Units (as defined herein) as shall result assuming a purchase price of
$0.80 per Unit.  Each Unit (the "Unit")  shall  consist of one share of Series A
Convertible  Preferred Stock, par value $.01 per share (the "Preferred Shares"),
and one  exchangeable  common  stock  purchase  warrant (the  "Warrants").  Each
Preferred Share will be convertible into one share (the "Conversion  Shares") of
the Company's common stock, par value $.01 per share (the "Common Stock"),  upon
the terms set forth in the Certificate of Designations,  Rights, Preferences and
Privileges  of the Series A Convertible  Preferred  Stock (the  "Certificate  of
Designations"),  attached  as Exhibit C to the  Confidential  Private  Placement
Memorandum  (as defined in Section 4.6  hereof.)  Each  Warrant  shall be issued
pursuant to a Warrant Agreement (the "Warrant Agent Agreement") substantially in
the form included as Exhibit D to the Confidential Private Placement Memorandum.
On its face  each  Warrant  will be  exchangeable  for such  number of shares of
common stock (the  "Warrant  Shares")  obtained by dividing (x) the value of the
Warrant  (determined by subtracting the aggregate  exercise price of the Warrant
from the  aggregate  fair market  value of the number of shares of Common  Stock
issuable  upon  exercise of the  Warrant),  by (y) the fair market  value of one
share  of  Common  Stock  prior  to the  exchange.  Each  Warrant  will  also be
exercisable for one share of Common Stock at an initial  exercise price of $0.90
per share (the "Warrant  Price").  The Conversion  Shares and the Warrant Shares
are referred herein as the "Underlying Common Shares."

                  SECTION 2.  Agreement to Sell and  Purchase the Units.  (a) At
the Closing (as defined in Section 3), the Company  will sell to the  Purchaser,
and the  Purchaser  will buy from the  Company,  upon the terms  and  conditions
hereinafter set forth, Debentures in the aggregate principal amount shown below:

                          [AGGREGATE PRINCIPAL AMOUNT]

                  (b) The  Company  proposes  to enter  into  this  same form of
purchase  agreement with certain other  investors (the "Other  Purchasers")  and
expects to complete sales of the Debentures to them. The Purchaser and the Other
Purchasers  are   hereinafter   sometimes   collectively   referred  to  as  the
"Purchasers,"  and this  Agreement  and the  agreements  executed  by the  Other
Purchasers  are   hereinafter   sometimes   collectively   referred  to  as  the


                             
<PAGE>

"Agreements." The term "Documents" shall mean this Agreement, the Certificate of
Designations  and the Warrant Agent Agreement,  collectively,  together with any
schedules or exhibits thereto.

                  (c) The Company reserves the right to reject this subscription
for  Debentures  in whole or in part at any time  before  the  Closing  Date (as
defined  below)  notwithstanding  prior  receipt by the  Purchaser  of notice of
acceptance  of his  subscription,  if the Company deems such action to be in its
best interests.

                  SECTION 3.  Delivery of the  Debentures  at the  Closing.  The
completion  of the purchase and sale of the  Debentures  (the  "Closing")  shall
occur at a place and time (the "Closing  Date") to be determined by the Company,
and of which the  Purchasers  will be  notified  by  facsimile  transmission  or
otherwise. At the Closing, the Company shall deliver to the Purchaser (i) one or
more Debenture certificates  registered in the name of the Purchaser, or in such
nominee  name(s) as  designated  by the  Purchaser,  representing  the principal
amount set forth in Section 2 above in such nominee  name(s)  designated  by the
Purchaser as set forth in the Debenture/Stock/Warrant  Certificate Questionnaire
attached hereto as part of Appendix I. The Company's  obligation to complete the
purchase and sale of the Debentures and deliver such Debenture certificate(s) to
the  Purchaser  at the  Closing  shall be subject to receipt of Federal  Reserve
(same-day)  funds in the full amount of the  purchase  price for the  Debentures
being purchased hereunder. The Purchaser's obligation to accept delivery of such
Debenture  certificate(s)  and to pay for the Debentures shall be subject to the
condition  that the Company  shall have (a) entered into a  Registration  Rights
Agreement  in  the  form  of  Appendix  III  hereto  (the  "Registration  Rights
Agreement") and (b) the accuracy in all material respects of the representations
and warranties  made by the Company  herein and the  fulfillment in all material
respects of those  undertakings of the Company to be fulfilled prior to Closing.
The Purchaser's obligations hereunder are not conditioned on the purchase by any
or all of the Other  Purchasers  of the  Debentures  that  they  have  agreed to
purchase  from the  Company.  The parties  agree that there may be more than one
Closing; provided, that any subsequent Closing must be held within seven days of
the initial Closing Date.

                  SECTION 4.        Representations,  Warranties   and Covenants
of the Company.  The Company hereby represents and warrants  to,  and  covenants
with, the Purchaser as follows:

                  4.1.  Organization and Qualification.  Each of the Company and
its subsidiaries is a corporation  duly organized,  validly existing and in good
standing  under  the  laws  of its  jurisdiction  of  incorporation  and has all
requisite  corporate  power and  authority  to conduct its business as currently
conducted.  Each of the Company and its subsidiaries is qualified to do business
as a foreign  corporation and is in good standing in each  jurisdiction in which
the failure to so qualify would have a material adverse effect on the operations
of the Company and its subsidiaries, taken as a whole.

                  4.2. Authorized Capital Stock; Authorization of Securities. As
of the date hereof,  the  authorized  capital  stock of the Company  consists of
fifteen million  (15,000,000)  shares of Common Stock, of which 4,067,632 shares
were validly issued and are outstanding,  fully paid and non-assessable.  Except
as set forth in the  Confidential  Private  Placement  Memorandum,  there are no
outstanding  securities  exercisable  for or convertible  into shares of capital
stock of the Company.


                                      -2-
<PAGE>

                  4.3.  Due   Execution,   Delivery  and   Performance   of  the
Agreements.  The  Company  has full  power  and  authority  to enter  into  this
Agreement and each Document.  This Agreement has been, and each Document and the
Debentures will be, duly authorized,  executed and delivered by the Company. The
Company's execution,  delivery and performance of this Agreement, the Debentures
and each Document will not violate (i) any law, rule or regulation applicable to
the Company or any of its  subsidiaries or (ii) the Certificate of Incorporation
or Bylaws of the Company or any of its  subsidiaries  or (iii) any  provision of
any material  indenture,  mortgage,  agreement,  contract or other instrument to
which the Company or any of its  subsidiaries is a party or by which the Company
or any of its  subsidiaries or any of their  properties or assets is bound as of
the date hereof, or result in a breach of or constitute (upon notice or lapse of
time or both) a default under any such material indenture,  mortgage, agreement,
contract or other  instrument  or result in the  creation or  imposition  of any
lien, security interest,  mortgage, pledge, charge or other encumbrance upon any
properties or assets of the Company or any of its  subsidiaries,  except, in the
case of such clause  (iii),  where such  violation,  breach or default would not
have a material adverse effect on the business, properties, prospects, condition
(financial or otherwise),  net worth or results of operations of the Company and
its  subsidiaries  taken as a whole (a "Material  Adverse  Effect").  Upon their
execution and delivery  (assuming the valid execution  thereof by the respective
parties thereto other than the Company),  this Agreement,  the Documents and the
Debentures  will  constitute  valid  and  binding  obligations  of the  Company,
enforceable in accordance with their respective terms,  except as enforceability
may be limited by applicable bankruptcy, insolvency, reorganization,  moratorium
or similar laws affecting  creditors' and contracting  parties' rights generally
and except as  enforceability  may be subject  to general  principles  of equity
(regardless  of whether such  enforceability  is  considered  in a proceeding in
equity or at law).

                  4.4.  Issuance,  Sale and  Delivery  of the  Debentures.  When
executed and delivered by the Company, the Debentures, will constitute valid and
legally binding  obligations of the Company  enforceable  against the Company in
accordance  with  their  terms,  except  as  enforceability  may be  limited  by
applicable bankruptcy,  insolvency,  reorganization,  moratorium or similar laws
affecting  creditors' and  contracting  parties  rights  generally and except as
enforceability  may be subject to general  principles of equity  (regardless  of
whether such  enforceability is considered in a proceeding at equity or at law).
The principal amount  outstanding  under the Debentures will be convertible into
Units in accordance with their terms and, the Preferred  Shares and the Warrants
comprising such Units will have been authorized and reserved for issuance within
120 days of the date  hereof  (the  "Authorization  Date"),  and when issued and
delivered  in  accordance  with the  terms of the  Debentures,  will be  validly
issued, fully paid and nonassessable.

                  4.5. Litigation. There is no action, suit or proceeding before
or by any  court or  governmental  agency  or body,  domestic  or  foreign,  now
pending, or, to the knowledge of the Company,  threatened,  against or affecting
the  Company  or  any  of  its  subsidiaries  which  are  not  described  in the
Confidential Private Placement Memorandum and which might result in any material
adverse  change in the  condition,  financial or otherwise,  or in the earnings,
business  affairs or business  prospects  of the  Company and its  subsidiaries,
taken as a whole, or which might  materially and adversely affect their property
or assets or which might  materially and adversely  affect the  consummation  of
this  Agreement  and the other  Documents.  All  pending  legal or  governmental
proceedings  to which the  Company or any of its  subsidiaries  is a party or of
which any of their  property or assets is the subject which are not described in
the  Confidential  Private  Placement  Memorandum (as defined below),  including
ordinary routine litigation  incidental to the business,  are, considered in the
aggregate,  not  material to the  business of the Company and its  subsidiaries,
taken as a whole.


                                      -3-
<PAGE>

                  4.6. Additional Information.  The information contained in the
following  documents  which the Company has furnished to the Purchaser,  or will
furnish  prior to the  Closing,  is or will be true and correct in all  material
respects as of their respective dates:

                  (a)      the Confidential  Private Placement  Memorandum dated
                           November 10, 1997  (including  all exhibits  thereto,
                           the  "Confidential  Private  Placement   Memorandum")
                           containing  certain summary  information  relating to
                           the sale of the  Debentures to the  Purchasers by the
                           Company  pursuant to the  Agreements,  including  all
                           addenda and exhibits thereto not listed below;

                  (b)      the  Company's  Annual  Report on Form 10-KSB for the
                           year ended December 31, 1996;

                  (c)      the  Company's  Quarterly  Report on Form  10-QSB for
                           the quarter ended March 31, 1997;

                  (d)      the  Company's  Quarterly  Report on Form  10-QSB for
                           the quarter ended June 30, 1997;

                  (e)      the  Company's  Quarterly  Report on Form  10-QSB for
                           the quarter ended September 30, 1997;

                  (f)      the  Company's  Current  Report  on  Form  8-K  dated
                           April 8, 1997;

                  (g)      the  Company's  Current   Report  on  Form  8-K dated
                           May 29, 1997; and

                  (h)      all other documents,  if any (the "Other Exchange Act
                           Documents"), filed by the Company with the Securities
                           and  Exchange  Commission  (the  "Commission")  since
                           September   30,  1997   pursuant  to  the   reporting
                           requirements of the Securities  Exchange Act of 1934,
                           as amended (the "Exchange Act").

                  4.7. No Material Change; No Material Misstatement or Omission.
(a) As of the date  hereof,  there has been no  material  adverse  change in the
consolidated  financial  condition,  business  or results of  operations  of the
Company  since  September  30,  1997.   Neither  the  Company  nor  any  of  its
subsidiaries  has incurred,  other than in the ordinary  course of its business,
any material  liabilities  or  obligations,  direct or  contingent,  nor has the
Company or any of its subsidiaries  purchased any of their  outstanding  capital
stock,  nor paid or  declared  any  dividends  or other  distributions  on their
capital  stock;  and  there  has  been  no  change  in  the  capital  stock  or,
consolidated  long-term  debt or, any  increase in the  consolidated  short-term
borrowings (other than in the ordinary course of business) of the Company or any
material  adverse  change  to  the  business,  properties,  assets,  net  worth,
condition  (financial  or other),  results of  operations  or  prospects  of the
Company and its subsidiaries, taken as a whole.

                  (b) As of the date thereof, the Confidential Private Placement
Memorandum,  including  all addenda and exhibits  thereto,  does not contain any
untrue statement of a material fact or omit to state a material fact required to
be stated therein or necessary in order to make the statements  therein,  in the
light of the circumstances under which they were made, not misleading.


                                      -4-
<PAGE>

                  4.8. Legal Opinion. Prior to closing, Hedger & Hedger, counsel
to the  Company,  will  deliver its legal  opinion to the Company in the form of
Appendix V hereto and stating  that each of the  Purchasers  may rely thereon as
though such opinion was addressed directly to such Purchaser.

                  4.9. Issuance of Units.  Commencing on the Authorization  Date
the Company  shall within three (3) business  days of the receipt by the Company
of any of the Debentures for conversion,  issue to such Purchaser, a certificate
or certificates  representing  the number of securities  comprising the Units to
which such  Purchaser  is  entitled,  which shall be legended as provided in the
Debentures. The Company shall issue Warrant Shares upon exercise of the Warrants
in accordance with the terms of the Warrant  Agreement,  which shall be legended
as provided therein.  After the Registration  Statement (as defined) is declared
effective by the  Commission,  if any holder of legended  Warrants or Underlying
Common Shares shall deliver to the Company (i) the certificate representing such
Warrants or Underlying Common Shares and (ii) a letter of representations to the
effect of Sections  5(b) and (c) herein,  then the Company  shall  within  three
business days after  receipt by the Company of the foregoing  issue new Warrants
or Underlying Common Shares in exchange for the aforementioned legended Warrants
or Underlying  Common  Shares,  which new Warrants or  Underlying  Common Shares
shall be legended as follows:

               THE  SHARES/WARRANTS  REPRESENTED BY THIS  CERTIFICATE  HAVE BEEN
               REGISTERED  UNDER THE  SECURITIES  ACT OF 1933,  AS AMENDED.  THE
               SHARES/WARRANTS   MAY  BE  SOLD  PURSUANT  TO  THE   REGISTRATION
               STATEMENT  PROVIDED THAT THE HOLDER  COMPLIES WITH THE PROSPECTUS
               DELIVERY  REQUIREMENTS  UNDER  THE  SECURITIES  ACT OF  1933,  AS
               AMENDED,  AND  THE  SALE  IS  IN  COMPLIANCE  WITH  THE  PLAN  OF
               DISTRIBUTION SET FORTH IN THE PROSPECTUS. THE SHARES/WARRANTS ARE
               SUBJECT  TO  CERTAIN  REGISTRATION  RIGHTS  AS  SET  FORTH  IN  A
               REGISTRATION  RIGHTS  AGREEMENT,  A COPY OF WHICH MAY BE OBTAINED
               FROM THE CORPORATION.

                  4.10. Certificate.  The Company shall deliver a certificate of
the Company  executed by the  Chairman of the Board or  President  and the chief
financial or accounting officer of the Company, to be dated the Closing Date, in
form  and  substance  satisfactory  to the  Purchasers  to the  effect  that the
representations  and  warranties  of the Company set forth in this Section 4 are
true and correct as of the date of this  Agreement  and as of the Closing  Date,
and the Company has  complied  with all the  agreements  and  satisfied  all the
conditions  on its part to be performed or satisfied on or prior to such Closing
Date.

                  4.11.  Authorization  Date.  The Company  agrees and covenants
with the Purchaser to use its best efforts to obtain the necessary authorization
for the issuance of the Preferred Shares prior to the Authorization Date.

                  SECTION 5.  Representations,  Warranties  and Covenants of the
Purchaser. (a) The Purchaser represents and warrants to, and covenants with, the
Company that: (i) the Purchaser is knowledgeable,  sophisticated and experienced
in making,  and is qualified to make,  decisions  with respect to investments in
shares  presenting an investment  decision like that involved in the purchase of


                                      -5-
<PAGE>

the Debentures,  including  investments in securities issued by the Company, and
has  requested,  received,  reviewed and  considered  all  information  it deems
relevant in making an informed  decision to purchase  the  Debentures;  (ii) the
Purchaser is acquiring the principal amount of Debentures set forth in Section 2
above  in the  ordinary  course  of its  business  and for its own  account  for
investment  (as  defined  for  purposes  of  the   Hart-Scott-Rodino   Antitrust
Improvement Act of 1976 and the regulations thereunder) only and with no present
intention of  distributing  any of such  Debentures,  Units,  Preferred  Shares,
Warrants or Underlying  Common Shares or any arrangement or  understanding  with
any other persons  regarding the  distribution  or purchase of such  Debentures,
Units,   Preferred   Shares,   Warrants  or   Underlying   Common  Shares  (this
representation  and  warranty  does  not  limit  the  Purchaser's  right to sell
pursuant to an  exemption  from  registration  or  pursuant to any  registration
statement  to be  filed  by the  Company  pursuant  to the  Registration  Rights
Agreement  or, other than with respect to any claims  arising out of a breach of
this representation and warranty, the Purchaser's right to indemnification under
the Registration  Rights  Agreement);  (iii) the Purchaser will not, directly or
indirectly,  offer, sell,  pledge,  transfer or otherwise dispose of (or solicit
any offers to buy, purchase or otherwise acquire or take a pledge of) any of the
Debentures, Units, Preferred Shares, Warrants or Underlying Common Shares except
in  compliance  with the  Securities  Act of 1933,  as amended (the  "Securities
Act"),  and the rules and  regulations  promulgated  thereunder and the Exchange
Act, and the rules and  regulations  promulgated  thereunder,  and the terms and
conditions of this  Agreement;  (iv) the Purchaser has completed or caused to be
completed    the     Registration     Statement     Questionnaire     and    the
Debenture/Stock/Warrant  Certificate  Questionnaire,  both  attached  hereto  as
Appendix I, for use in preparation of the Registration Statement and the answers
thereto are true and correct to the best  knowledge  of the  Purchaser as of the
date  hereof  and  will be true  and  correct  as of the  effective  date of the
Registration  Statement;  (v) the Purchaser has, in connection with its decision
to purchase the  principal  amount of  Debentures  set forth in Section 2 above,
relied  solely  upon  the  Confidential  Private  Placement  Memorandum  and the
representations  and warranties of the Company contained in writing herein,  and
has not relied upon any other statements, representations, warranties, covenants
or assurances of the Company,  (vi) the  Purchaser is an  "accredited  investor"
within the meaning of Rule 501 of Regulation D promulgated  under the Securities
Act  ("Regulation  D"); and (vii) the Purchaser  understands that the Debentures
and the  Preferred  Shares and,  except as  provided in Section 4.9 hereof,  the
Warrants and the Underlying Common Shares will contain a legend to the following
effect (provided that  certificates for the Preferred Shares shall omit the last
sentence thereof):

                  THE SECURITIES  REPRESENTED BY THIS  CERTIFICATE HAVE NOT BEEN
                  REGISTERED  UNDER THE SECURITIES ACT OF 1933, AS AMENDED.  THE
                  SECURITIES  HAVE BEEN ACQUIRED FOR  INVESTMENT  AND MAY NOT BE
                  SOLD,  TRANSFERRED  OR  ASSIGNED  IN THE  ABSENCE OF EITHER AN
                  EFFECTIVE  REGISTRATION  STATEMENT  FOR THESE SHARES UNDER THE
                  SECURITIES  ACT OF 1933, AS AMENDED,  OR AN OPINION OF COUNSEL
                  THAT  REGISTRATION  IS NOT  REQUIRED  UNDER  SAID  ACT.  THESE
                  SECURITIES ARE SUBJECT TO CERTAIN  REGISTRATION  RIGHTS AS SET
                  FORTH IN A REGISTRATION RIGHTS AGREEMENT,  A COPY OF WHICH MAY
                  BE OBTAINED FROM THE COMPANY.



                                      -6-
<PAGE>


                  (b) The Purchaser  hereby  covenants  with the Company that it
will not directly or indirectly make any offer, sale, pledge,  transfer or other
disposition of the Debentures,  the Units, the Preferred Shares, the Warrants or
the  Underlying  Common  Shares  other than in  accordance  with all  applicable
federal  and  state  securities  laws  and  the  terms  and  conditions  of this
Agreement, including, but not limited to, the other representations,  warranties
and covenants of the Purchaser in this Section 5.

                  (c) The  Purchaser  hereby  covenants  with the Company not to
make  any  sale  of  the  Warrants  or  the  Underlying  Common  Shares  without
effectively causing the prospectus delivery requirement under the Securities Act
to be satisfied, and the Purchaser acknowledges and agrees that the Warrants and
the Underlying  Common Shares are not  transferable  on the books of the Company
unless the certificate  submitted to the transfer agent  evidencing the Warrants
or  the  Underlying  Common  Shares  is  accompanied  by  a  separate  officer's
certificate:  (i) in the form of Appendix IV hereto, (ii) executed by an officer
of, or other authorized  person  designated by, the Purchaser,  and (iii) to the
effect that (A) the Underlying Common Shares have been sold in accordance with a
Registration   Statement  and  (B)  the  requirement  of  delivering  a  current
prospectus has been satisfied.

                  (d) The  Purchaser  further  represents  and  warrants to, and
covenants  with,  the Company  that (i) the  Purchaser  has full  right,  power,
authority  and  capacity  to enter into this  Agreement  and to  consummate  the
transactions contemplated hereby and has taken all necessary action to authorize
the execution,  delivery and  performance of this  Agreement,  and (ii) upon the
execution and delivery of this  Agreement,  this  Agreement  shall  constitute a
valid and binding obligation of the Purchaser enforceable in accordance with its
terms,  except  as  enforceability  may be  limited  by  applicable  bankruptcy,
insolvency, reorganization,  moratorium or similar laws affecting creditors' and
contracting  parties'  rights  generally  and  except as  enforceability  may be
subject  to  general   principles   of  equity   (regardless   of  whether  such
enforceability is considered in a proceeding in equity or at law).

                  (e) The Purchaser  acknowledges that it has had such access to
financial and other  information  concerning the Company,  the  Debentures,  the
Units,  the  Preferred  Shares  and  the  Warrants  as it  deemed  necessary  in
connection  with its  decision to purchase  the  Debentures  and the  underlying
Preferred Shares and the Warrants, including an opportunity to ask questions and
request  information  from the Company and its management and all such questions
have been  answered  and all  information  requested  has been  provided  to the
satisfaction  of the  Purchaser and has not relied on any third party to conduct
due diligence.

                  (f) If the  Purchaser  proposes  to sell,  pledge,  assign  or
otherwise transfer or convey, directly or indirectly, any of the Debentures, the
Units,  Preferred Shares,  the Warrants or the Underlying Common Shares prior to
the date that the Registration  Statement becomes effective,  then the Purchaser
shall  provide the  Company,  prior to the sale of any such  Debentures,  Units,
Preferred  Shares,  the Warrants or the  Underlying  Common  Shares with a legal
opinion in form and  substance  satisfactory  to the  Company  of legal  counsel
satisfactory  to the Company  that such sale,  pledge,  assignment,  transfer or
conveyance is exempt from the registration requirements under the Securities Act
and any applicable state securities and blue sky laws.

                  SECTION 6. Additional Interest. The Company and the Purchasers
agree that the  holders of the  Debentures  will  suffer  damages if the Company
fails to promptly, but in no event later than the Authorization Date, obtain the
necessary  authorization  for the issuance of the Preferred Stock comprising the


                                      -7-
<PAGE>

Units and the additional  shares of Common Stock  underlying  the Warrants,  and
that it would not be  feasible  to  ascertain  the extent of such  damages  with
precision.  The Company agrees that if it has failed within 120 days of the date
hereof to obtain the necessary  authorization  it shall pay additional  interest
("Additional  Interest") on the Debentures.  Additional Interest shall accrue on
the principal  amount of the Debentures  over and above the stated interest at a
rate of 6.0% per annum and such  Additional  Interest  rate shall  increase at a
rate of an additional 1.5% per annum at the beginning of each subsequent  90-day
period.

                  SECTION 7.        Survival of Representations, Warranties  and
Agreements.  Notwithstanding  any  representation  made  by any  party  to  this
Agreement, all covenants, agreements, representations and warranties made by the
Company and the  Purchaser  in writing  herein and in the  closing  certificates
delivered  pursuant  hereto shall survive the execution of this  Agreement,  the
delivery to the  Purchaser of the  Debentures  being  purchased  and the payment
therefor.

                  SECTION  8.  Registration  of  Underlying  Common  Shares.  In
recognition of the fact that Purchasers, even though purchasing Preferred Shares
and  Warrants  for  investment,  may wish to be  legally  permitted  to sell the
Underlying Common Shares when they deem  appropriate,  the Company has agreed to
use its best  efforts to prepare  and file with the  Commission  a  Registration
Statement  (the  "Registration  Statement")  with  respect  to the resale of the
Underlying  Common Shares from time to time through the Nasdaq SmallCap  Market,
the  Boston  Stock  Exchange,   Pacific  Exchange  or  in   privately-negotiated
transactions all as described more fully in the Registration Rights Agreement.

                  SECTION 9.  Broker's  Fee.  Each of the parties  hereto hereby
represents  that, on the basis of any actions and agreements by it, there are no
brokers or finders  entitled to  compensation in connection with the sale of the
Debentures, the Units, the Preferred Shares and the Warrants to the Purchaser.

                  SECTION 10. Notices. All notices, requests, consents and other
communications  hereunder  shall be in writing,  shall be by telecopier,  with a
copy being mailed by a nationally  recognized  overnight  express  courier,  and
shall be deemed  given when  receipt is  acknowledged  by transmit  confirmation
report and shall be addressed as follows:

                  (a)      if to the Company, to:

                                    Derma Sciences, Inc.
                                    214 Carnegie Center, Suite 100
                                    Princeton, New Jersey  08540
                                    Telephone:  (800) 825-4325
                                    Telecopier:  (609) 452-0880

                           or to such other  person at such  other  place as the
                           Company shall designate to the Purchaser in writing;

                  (b)      if to the  Purchaser,  at its address and  telecopier
                           number as set forth at the end of this Agreement,  or
                           at such other  address or  addresses as may have been
                           furnished to the Company in writing.


                                      -8-
<PAGE>

                  SECTION 6.          Changes.  This   Agreement  may   not   be
modified or amended  except  pursuant to an instrument in writing  signed by the
Company and the Purchaser.

                  SECTION 7.          Headings.    The  headings  of the various
sections of this Agreement have been inserted for  convenience of reference only
and shall not be deemed to be part of this Agreement.

                  SECTION 8.  Severability.  In case any provision  contained in
this Agreement should be invalid,  illegal or unenforceable in any respect,  the
validity,  legality and  enforceability  of the remaining  provisions  contained
herein shall not in any way be affected or impaired thereby.

                  SECTION 9.         Governing  Law.  This  Agreement  shall  be
governed by and construed in  accordance  with the laws of the State of New York
(without  reference  to its rules as to conflicts of law) and the federal law of
the United States of America.

                  SECTION 10.  Counterparts.  This  Agreement may be executed in
two or more counterparts, each of which shall constitute an original, but all of
which,  when taken  together,  shall  constitute but one  instrument,  and shall
become  effective when one or more  counterparts  have been signed by each party
hereto and delivered to the other parties.  Facsimile  signatures are considered
to be originals and shall have the same effect.

                  SECTION 11. Entire  Agreement.  This  Agreement is intended by
the  parties as a final  expression  of their  agreement  and  intended  to be a
complete and  exclusive  statement of the  agreement  and  understanding  of the
parties hereto in respect of the subject matter contained herein. This Agreement
supersedes  all prior  agreements  and  understandings  between the parties with
respect to such subject matter.



                                      -9-
<PAGE>


                  IN WITNESS WHEREOF, the Purchaser has caused this Agreement to
be executed by its duly authorized  representative  as of the day and year first
above written.

Print or Type:                              Name of Purchaser
                                            (Individual or Institution):


                                            ------------------------------------

                                            Name of Individual representing
                                            Purchaser (if an Institution):



                                            ------------------------------------


                                            Title of Individual representing
                                            Purchaser (if an Institution):



                                            ------------------------------------

Signature by:
                                            Individual Purchaser or Individual
                                            representing Purchaser:



                                            ------------------------------------


                                            Address:____________________________


                                            ------------------------------------


                                            ------------------------------------

                                            Telephone:__________________________

                                            Telecopier:_________________________


ACCEPTED AND AGREED TO
THIS ___ DAY OF NOVEMBER, 1997:

DERMA SCIENCES, INC.


By:      -----------------------
         Edward J. Quilty
         Chairman


                                      -10-
<PAGE>



                                                                    Appendix I-1
                                                                    (one of two)


DERMA SCIENCES, INC.

DEBENTURE/STOCK/WARRANT CERTIFICATE QUESTIONNAIRE



         Pursuant  to  Section 3 of the  Agreement,  please  provide us with the
following information:



<PAGE>


1.      The exact name that your Debentures are to be
        registered in (this is the name that will appear on
        your certificate(s)).  You may use a nominee name if
        appropriate:


                                                     ---------------------------



2.      The relationship  between the Purchaser and the 
        Registered Holder listed in response to item 1:


                                                      --------------------------


3.      The mailing address of the Registered Holder listed
        in response to item 1 above:


                                                     ---------------------------

        



4.      The Social Security Number or Tax Identification
        Number of the Registered Holder listed in response to item 1 above:



                                                      --------------------------



<PAGE>


                                                                    Appendix I-2
                                                                    (two of two)

DERMA SCIENCES, INC.
REGISTRATION STATEMENT QUESTIONNAIRE


                  In  connection  with  the  preparation  of  the   Registration
Statement, please provide us with the following information:



<PAGE>


                  1.  Please  state  the  name of the  beneficial  owner  of the
Debentures  to be  purchased  pursuant to the  Purchase  Agreement to which this
Appendix  I-2 is  attached.  This is the name that will  appear in the  "Selling
Securityholder" section of the Registration Statement.





- --------------------------------------------------------------------------------







                  2. Please provide below the number of: (1) Units  purchased by
the person or entity named in Item 1 above;  (2) Preferred  Shares  purchased by
the person or entity named in Item 1 above; (3) Warrants purchased by the person
or entity named in Item 1 above;  and (4) shares of Common Stock that the person
or entity named in Item 1 above owned at November 10, 1997:


       (1)                (2)                  (3)                (4)
 Number of Units        Number of           Number of      Number of Shares of
   Purchased        Preferred Shares        Warrants      Common Stock Owned at
                       Purchased           Purchased        November 10, 1997
 ---------------    ----------------       ----------     ---------------------


<PAGE>


                  3. Unless you check the following box, all  Underlying  Common
Shares  relating to the Preferred  Shares and the Warrants  listed above will be
included in the Registration Statement.


                                [  ]



If you checked the foregoing box,  please  indicate a lesser number of Preferred
Shares or  Warrants  to be used to  determine  the number of  Underlying  Common
Shares to be included in the Registration Statement.




- --------------------------------------------------------------------------------





                  4. Have you, your  organization or the beneficial  owner named
above had any position,  office or other material  relationship  within the past
three years with the Company or its  affiliates  other than as  disclosed in the
Prospectus included in the Registration Statement?

                                    ____ Yes         ____ No

                  If yes, please  indicate the nature of any such  relationships
below:











<PAGE>

                                                                     Appendix II


                                CONVERSION NOTICE

                         URGENT/FOR IMMEDIATE ATTENTION

                                  addressed to:

                                    Derma Sciences, Inc.
                                    214 Carnegie Center, Suite 100
                                    Princeton, New Jersey  08540
                                    Telephone:  (800)  825-4325
                                    Telecopier:  (609)  452-0880

Name of Nominee or Registered Holder:

 ...............................................................................
(Print)

Telecopier  number to which  confirmation of receipt of this  Conversion  Notice
should be sent:

 ...............................................................................


Number of shares of Preferred Stock being converted hereby: ___________________

If you want the Common Stock  certificate,  if any, made out in another person's
name, fill in the form below:

                    (INSERT OTHER PERSON'S SOCIAL SECURITY OR
                  TAX IDENTIFICATION NUMBER, WHERE APPLICABLE)

                                [            ]

 ................................................................................

 ................................................................................

 ................................................................................

 ................................................................................
(Print or type assignee's name, title, address and zip code)

Date:...........................................................................

Your
Signature:.....................................................................

<PAGE>


                                                                    Appendix III

                          REGISTRATION RIGHTS AGREEMENT



                          Please refer to Exhibit 10.02



<PAGE>


                                                                     Appendix IV

Attention:

                   PURCHASER'S CERTIFICATE OF SUBSEQUENT SALE

         The undersigned, [an officer of, or other person duly authorized by]



- --------------------------------------------------------------------------------
             [fill in official name of individual or institution]

hereby certifies that he/she [said institution] is the Purchaser of the shares/

warrants evidenced by the attached certificate, and as such, sold such shares/

warrants on ______________________ in accordance with registration statement
                    [date]
number ____________________________________________________________________
           [fill in number or otherwise identify registration statement]

and the requirement of delivering a current prospectus and current annual and

quarterly  reports by the Company has been complied with in connection with such

sale.

Print or Type:

                  Name of Purchaser
                    (Individual or
                     Institution):___________________________________________

                  Name of Individual
                    representing Purchaser
                    (if an Institution):_____________________________________


                  Title of Individual
                    representing Purchaser
                   (if an Institution):______________________________________


Signature by:                  
                  Individual Purchaser
                    or Individual
                    representing
                    Purchaser:_______________________________________________


<PAGE>


                                                                      APPENDIX V


                    FORM OF OPINION OF COUNSEL TO THE COMPANY

         1. The Company is a corporation duly organized, validly existing and in
good standing under the laws of its  jurisdiction of  incorporation  and has all
requisite  corporate  power and  authority  to conduct its business as currently
conducted.

         2. As of the date hereof,  the authorized  capital stock of the Company
consists of (i) fifteen million  (15,000,000)  shares of common stock, par value
$.01 per share ("Common  Stock"),  of which 4,067,632  shares are validly issued
and  outstanding.  To such  counsel's  knowledge,  except  as set  forth  in the
Confidential Private Placement Memorandum,  there are no outstanding  securities
exercisable for or convertible into shares of capital stock of the Company.

         3.  The  Debentures  to be  issued  and  sold  by  the  Company  to the
Purchasers  will be, upon issuance and payment  therefor,  duly  authorized  and
validly  issued and  legally  binding  obligations  of the  Company  enforceable
against it in accordance  with their terms and entitled to be benefits  thereof.
The principal amount  outstanding  under the Debentures will be convertible into
the Units in accordance with their terms on or after the Authorization Date.

         4. The Company has full  corporate  power and  authority  to enter into
this Agreement and each Document. This Agreement has been, and each Document and
the Debentures will be, duly authorized,  executed and delivered by the Company.
The  Company's  execution,  delivery  and  performance  of this  Agreement,  the
Debentures  and  each  Document  will  not  violate  (i)  any  statute,  rule or
regulation  known  to  such  counsel  to be  applicable  to the  Company  or its
subsidiaries, (ii) to the best of such counsel's knowledge, any order, judgment,
ruling or decree of any court or any governmental,  regulatory or administrative
body applicable to the Company or any of its subsidiaries, (iii) the Certificate
of  Incorporation  or  Bylaws  of the  Company,  or (iv)  any  provision  of any
indenture,  mortgage,  agreement,  contract or other instrument (X) filed by the
Company with (A) its quarterly  reports on Form 10-QSB for the quarterly periods
ended March 31, 1997,  June 30, 1997 and  September  30, 1997,  (B) filed by the
Company  with its Annual  Report on Form 10-KSB for the year ended  December 31,
1996,  and (C) all  other  Exchange  Act  Documents  or result in a breach of or
constitute  (upon notice or lapse of time or both) a default  under any thereof,
or  result  in the  creation  or  imposition  of any  lien,  security  interest,
mortgage,  pledge,  charge or other encumbrance upon any properties or assets of
the  Company  or any of its  subsidiaries,  except in the case of the  foregoing
clauses  (i),  (ii) and (iv) for those  violations,  breaches or defaults  which
would not singly or in the aggregate, have a Material Adverse Effect. Upon their
execution and delivery  (assuming the valid execution  thereof by the respective
parties thereto other than the Company),  this Agreement,  the Documents and the
Debentures  will  constitute  valid  and  binding  obligations  of the  Company,
enforceable in accordance with their respective terms,  except as enforceability
may be limited by applicable bankruptcy, insolvency, reorganization,  moratorium
or similar laws affecting  creditors' and contracting  parties' rights generally
and except as  enforceability  may be subject  to general  principles  of equity
(regardless  of whether such  enforceability  is  considered  in a proceeding in
equity or at law).

<PAGE>


         5.  Except  as  described  in  the   Confidential   Private   Placement
Memorandum,  to such counsel's  knowledge (without  independent  investigation),
there is no action,  suit or proceeding  before or by any court or  governmental
agency or body,  domestic or foreign,  now pending,  or  threatened,  against or
affecting the Company or any of its subsidiaries  which might,  singly or in the
aggregate,  have a  Material  Adverse  Effect,  or which  might  materially  and
adversely affect the consummation of this Agreement and the other Documents;  to
such counsel's knowledge without independent  investigation all pending legal or
governmental  proceedings to which the Company or any of its  subsidiaries  is a
party or of which any of their  property or assets is the subject  which are not
described in the Confidential Private Placement  Memorandum,  including ordinary
routine litigation incidental to the business, are, considered in the aggregate,
not  material to the  business of the Company and its  subsidiaries,  taken as a
whole.

         6. To such counsel's knowledge,  no consent,  approval,  authorization,
order,  registration,  filing,  qualification,  license or permit of or with any
court  or  any  public,  governmental,  or  regulatory  agency  or  body  having
jurisdiction  over  the  Company  or  any of its  subsidiaries  or any of  their
respective  properties  or assets is required  for the  execution,  delivery and
performance  of  this  Agreement  or  the   consummation  of  the   transactions
contemplated  hereby,  except  for  such  as  may be  required  by  under  state
securities or Blue Sky laws in connection with the purchase and  distribution of
the Debentures (as to which such counsel need express no opinion).




                          REGISTRATION RIGHTS AGREEMENT


         THIS  REGISTRATION  RIGHTS  AGREEMENT  (the  "Agreement")  is made  and
entered into as of November 11, 1997,  by and between  Derma  Sciences,  Inc., a
Pennsylvania  corporation  (the  "Company"),  and the  purchaser  whose name and
address is set forth on the signature page hereof (the "Purchaser").

         This Agreement is made pursuant to the Purchase Agreement,  dated as of
November  11,  1997,  between  the  Company  and the  Purchaser  (the  "Purchase
Agreement").  In order to  induce  the  Purchaser  to  enter  into the  Purchase
Agreement,  the Company  has agreed to provide for the benefit of the  Purchaser
and the Other  Purchasers  (as  defined  below) of the  Debentures  (as  defined
below), and any subsequent holders of Registrable Securities (as defined below),
the  registration  rights set forth in this  Agreement.  The  execution  of this
Agreement is a condition to the closing under the Purchase Agreement.

   
         The  Company  proposes  to enter into  substantially  this same form of
registration   rights   agreement  with  certain  other  investors  (the  "Other
Purchasers")  and  expects to  complete  sales of  Preferred  Shares (as defined
below) and  Warrants (as defined  below) to them.  The  Purchaser  and the Other
Purchasers  are   hereinafter   sometimes   collectively   referred  to  as  the
"Purchasers," and this Agreement and the registration rights agreements executed
by the Company and the Other Purchasers are hereinafter  sometimes  collectively
referred to as the "Agreements."
    

         The parties hereby agree as follows:

1.       Definitions

         As used in this Agreement,  the following  capitalized terms shall have
the following meanings:

          Authorization Date: Has the meaning such term is given in the Purchase
     Agreement.

          Certificate of  Designations:  Means the Certificate of  Designations,
     Rights,  Preferences  and  Privileges  of the Series A  Convertible  Stock,
     attached as Exhibit C to the Confidential Private Placement Memorandum.

          Closing  Date:  Has the  meaning  such  term is given in the  Purchase
     Agreement.

          Common Stock:  The shares of common stock, par value $.01 per share of
     the Company.

          Confidential  Private Placement  Memorandum:  The Confidential Private
     Placement  Memorandum  dated  November 10, 1997  prepared by the Company in
     connection with the private placement of the Debentures.

<PAGE>


          Conversion  Notice:  Has  the  meaning  such  term  is  given  in  the
     Certificate of Designations.

          Conversion  Ratio:  The Conversion  Ratio has the meaning such term is
     given in the Certificate of Designations.

          Conversion Shares: Shares of Common Stock issuable upon the conversion
     of the Preferred Shares. Each Preferred Share initially will be convertible
     into one Conversion Share.

          Debentures:  The Company's Convertible  Debentures due 1998 being sold
     and issued  pursuant to the Purchase  Agreement in the aggregate  principal
     amount set forth therein.

          Effective  Date:  The date that the Resale  Registration  Statement is
     declared effective by the SEC.

          Exchange  Act: The  Securities  Exchange Act of 1934,  as amended from
     time to time.

          Holder:  Each  beneficial  holder  from  time to  time of  Registrable
     Securities.

          Indemnified Holder: See Section 6(a).

          NASD: National Association of Securities Dealers, Inc.

          Person:   An   individual,   partnership,    corporation,   trust   or
     unincorporated  organization,  or  a  government  or  agency  or  political
     subdivision thereof.

          Preferred Shares:  The shares of Series A Convertible  Preferred Stock
     of  the  Company,  par  value  $.01  per  share,  issued  pursuant  to  the
     Certificate of Designations, as part of the Units.

          Prospectus:  The prospectus included in any Registration Statement, as
     supplemented by any prospectus supplement and as amended by all amendments,
     including  post-effective  amendments  and  all  material  incorporated  by
     reference in such prospectus.

          Registrable Securities: The Underlying Common Shares; provided that an
     Underlying Common Share ceases to be a Registrable Security when it (i) has
     been  effectively  registered  under  Section 5 of the  Securities  Act and
     disposed of in accordance with any  Registration  Statement,  (ii) has been
     distributed  to the public  pursuant to Rule 144 under the  Securities  Act
     ("Rule 144") (or any similar provisions then in force) or (iii) is eligible
     for  distribution  to the public by the Holder  pursuant to Rule 144(k) (or
     any similar provisions then in force).

          Registration Expenses: See Section 5.

                                       2
<PAGE>

          Registration  Statement:  Any  registration  statement  of the Company
     which, in accordance  with Section 3 hereof,  covers any of the Registrable
     Securities  pursuant to the  provisions  of this  Agreement,  including the
     Prospectus,  amendments  and  supplements to such  Registration  Statement,
     including  post-effective  amendments,  and all  exhibits  and all material
     incorporated by reference in such Registration Statement.

          Resale Registration Statement: See Section 3.

          Securities  Act: The  Securities  Act of 1933, as amended from time to
     time.

          SEC: The Securities and Exchange Commission.

          Underlying  Common  Shares:  The  Conversion  Shares  and the  Warrant
     Shares.

          Units: The Company's  Units,  each consisting of one share of Series A
     Convertible  Preferred Stock, $.01 par value, and one Common Stock Purchase
     Warrant.

          Warrant  Agreement:  The Warrant  Agreement  dated  November  11, 1997
     between the Company and StockTrans, Inc., as warrant agent, and included as
     Exhibit D to the Confidential Private Placement Memorandum, as contemplated
     by the Purchase Agreement.


          Warrant  Price:  Has the  meaning  such  term is given in the  Warrant
     Agreement.

          Warrants:  The Common Stock Purchase  Warrants  issued pursuant to the
     Warrant  Agreement  and  pursuant  to  the  Purchase  Agreements  with  the
     Purchaser and the other Purchasers.

          Warrant  Shares:  The shares of Common Stock issuable upon exercise of
     the Warrants.

2.       Securities Subject to this Agreement

         Each  holder  from  time to time of  Registrable  Securities  shall  be
entitled to the benefits of this Agreement. A Person is deemed to be a Holder of
Registrable   Securities  whenever  such  Person  is  the  beneficial  owner  of
Registrable  Securities.  The Company is entitled to treat the record  holder of
Registrable  Securities as beneficial  owner of  Registrable  Securities  unless
otherwise notified by such holder.

3.       Resale Registration: Timing of Filing, Effectiveness and Period of 
         Usability

         Subject to the  provisions of Section 4 hereof,  the Company shall file
and use its best  efforts to cause to be declared  effective  not later than the
later of: (i) the  Authorization  Date or (ii) 90 days from the date  hereof,  a
"resale"  Registration  Statement (a "Resale  Registration")  on any appropriate
form under the Securities  Act for all the  Registrable  Securities,  which form
shall be available for the sale of the Registrable Securities in accordance with
the untraded methods of distribution thereof.

                                       3
<PAGE>

         The  Company  agrees to use its best  efforts to keep the  Registration
Statement continuously effective and usable for resale of Registrable Securities
until  365 days  (the  "Effectiveness  Period")  from the  Closing  Date or such
shorter period which shall terminate when all the Registrable Securities covered
by such  Registration  Statement  have been sold  pursuant to such  Registration
Statement or when all Registrable  Securities  otherwise have been sold pursuant
to  Rule  144  or are  freely  tradeable  in  essentially  the  same  manner  as
contemplated in Section 4 below.

4.       Registration Procedures

         In  connection  with  the  Company's  obligation  to file  Registration
Statements as provided in Section 3 hereof, the Company will as expeditiously as
possible:

     (a) before filing a Registration  Statement or Prospectus or any amendments
or supplements  thereto,  furnish to the Holders of the  Registrable  Securities
covered by such Registration  Statement a copy of all such documents proposed to
be filed, which documents will be subject to the review of such Holders, and the
Company will not file any  Registration  Statement  or amendment  thereto or any
Prospectus  or any  supplement  thereto to which the  Holders  of a majority  in
aggregate  principal  amount  of the  Registrable  Securities  covered  by  such
Registration  Statement shall  reasonably  object (provided that the Company may
assume,  for the  purposes  of the  foregoing  that any  Holder  of  Registrable
Securities  has no objection  if the Company has not  received  notice from such
Holder  within  five  business  days after  delivery of such  documents  to such
Holder);

     (b) prepare and file with the Commission such amendments and post-effective
amendments  to  the  Registration   Statement,   and  such  supplements  to  the
Prospectus,  as may  be  required  by the  rules,  regulations  or  instructions
applicable to the registration form utilized by the Company or by the Securities
Act or rules and  regulations  thereunder  or  otherwise  necessary  to keep the
Registration  Statement  effective  for the  applicable  period  and  cause  the
Prospectus  as so  supplemented  to be  filed  pursuant  to Rule 424  under  the
Securities  Act;  and comply  with the  provisions  of the  Securities  Act with
respect  to the  disposition  of all  securities  covered  by such  Registration
Statement  during the applicable  period in accordance with the intended methods
of disposition by the sellers thereof set forth in such  Registration  Statement
or supplement to the Prospectus;

     (c) notify  Purchaser and the Holders of Registrable  Securities  promptly,
and confirm such advice in writing,

                           (1) when the Prospectus or any Prospectus  supplement
                  or post-effective  amendment has been filed, and, with respect
                  to the Registration Statement or any post-effective amendment,
                  when the same has become effective,

                                       4
<PAGE>

                           (2) of the  issuance  by the  SEC of any  stop  order
                  suspending the effectiveness of the Registration  Statement or
                  the initiation of any proceedings for that purpose, and

                           (3) of the receipt by the Company of any notification
                  with respect to the  suspension  of the  qualification  of the
                  Registrable  Securities  for sale in any  jurisdiction  or the
                  initiation or threatening of any proceeding for such purpose;

     (d) make  every  reasonable  effort to obtain the  withdrawal  of any order
suspending  the  effectiveness  of the  Registration  Statement  at the earliest
possible moment;

     (e) furnish, without charge, to Purchaser and, upon request, each Holder of
Registrable  Securities,  at  least  one  conformed  copy  of  the  Registration
Statement  and  any  post-effective   amendment  thereto,   including  financial
statements and schedules,  all documents  incorporated  therein by reference and
all exhibits (including those incorporated by reference);

     (f) deliver to Purchaser and each Holder of Registrable  Securities without
charge, as many copies of the Prospectus (including each preliminary prospectus)
and any amendment or supplement thereto as such Persons may reasonably  request;
the Company consents to the use of the Prospectus or any amendment or supplement
thereto  by  each  Purchaser  and  each  Holder  of  Registrable  Securities  in
connection with the offering and sale of the Registrable  Securities  covered by
the Prospectus or any amendment or supplement thereto;

     (g) use its reasonable efforts to cause the Registrable  Securities covered
by the  Registration  Statement  to be  registered  with  or  approved  by  such
governmental  agencies or  authorities as may be necessary to enable the Holders
thereof to consummate  the  disposition of such  Registrable  Securities in such
jurisdictions as the Holders may reasonably  specify in response to inquiries to
be made by the  Company,  provided  that the  Company  will not be  required  to
qualify  generally  to do business in any  jurisdiction  where it is not then so
qualified  or to take any action  which would  subject it to general  service of
process in any such jurisdiction where it is not then so subject;

     (h) if any event shall occur as a result of which it is  necessary,  in the
opinion of counsel for the Company,  to amend or  supplement  the  Prospectus in
order to make the Prospectus  not  misleading in the light of the  circumstances
existing  at the time it is  delivered  by a  Holder,  prepare a  supplement  or
post-effective amendment to the Registration Statement or the related Prospectus
or any document  incorporated  therein by  reference or file any other  required
document so that,  as  thereafter  delivered  to the Holders of the  Registrable
Securities,  the Prospectus  will not contain an untrue  statement of a material
fact or omit to state any material fact necessary to make the statements therein
not misleading;

                                       5
<PAGE>

     (i) obtain a CUSIP number for all  Registrable  Securities  (unless already
obtained), not later than the Effective Date;

     (j)  make  available  for  inspection  during  normal  business  hours by a
representative  of the Holders of a majority of the  Registrable  Securities and
any attorney or accountant  retained by such  representative,  all financial and
other records,  pertinent corporate documents and properties of the Company, and
cause the Company's officers,  directors and employees to supply all information
reasonably  requested  by such  Holders or any such  attorney or  accountant  in
connection  with the  Registration  Statement;  provided  that all such records,
information  or documents  shall be kept  confidential  by such  Persons  unless
disclosure  of such  records,  information  or documents is required by court or
administrative  order or is  generally  available  to the public other than as a
result of disclosure in violation of this paragraph (j);

     (k) otherwise use its best efforts to comply with all applicable  rules and
regulations of the SEC, and make generally  available to its security holders an
earnings statement  satisfying the provisions of Section 11(a) of the Securities
Act (in accordance with Rule 158 thereunder or otherwise), no later than 45 days
after the end of the  12-month  period (or 90 days,  if such  period is a fiscal
year)  beginning  with the first month of the  Company's  first  fiscal  quarter
commencing  after the Effective Date, which statements shall cover said 12-month
period;

     (l) if at any time an event of the kind  described  in  Section  4(h) shall
occur,  notify Purchaser and the Holders of Registrable  Securities that the use
of the Prospectus  must be  discontinued  (the Company will not declare any such
"black-out"  periods in excess of twenty  business  days during any twelve month
period, unless otherwise required); and

     (m)  on or  prior  to the  date  the  Registration  Statement  is  declared
effective by the SEC, cause all of the Underlying Common Shares to be listed for
trading on the  Boston  Stock  Exchange  or  Pacific  Exchange  (or on any other
national  securities  exchange  or the  Nasdaq  SmallCap  Market)  on which  the
Company's shares of Common Stock are then listed.

     Each Holder of Registrable Securities as to which any registration is being
effected agrees, as a condition to the registration  obligations with respect to
such  Holder  provided  herein,  to  furnish  to the  Company  such  information
regarding the  distribution  of such  Registrable  Securities as the Company may
from time to time reasonably request in writing.

     Each  Holder  of  Registrable  Securities  agrees  by  acquisition  of such
Registrable  Securities  that,  upon  receipt  of any  notice  from the  Company
described  in this  paragraph  4(k),  such  Holder  will  forthwith  discontinue
disposition of Registrable  Securities until such Holder's receipt of the copies
of the supplemented or amended  Prospectus  contemplated by Section 4(g) hereof,
or until it is advised in writing by the Company (which notice the Company shall
give as promptly as possible),  that the use of the  Prospectus  may be resumed,
and has


                                       6
<PAGE>


received copies of any additional or supplemental filings which are incorporated
by reference in the Prospectus,  and, if so directed by the Company, such Holder
will deliver to the Company (at the  Company's  expense) all copies,  other than
permanent  file  copies  then in such  Holder's  possession,  of the  Prospectus
covering  such  Registrable  Securities  current  at the time of receipt of such
notice.

5.       Registration Expenses

     (a) All expenses  incident to the  Company's  performance  of or compliance
with this Agreement, including without limitation:

                  (1)      all registration, filing and listing fees;

                  (2) fees and expenses of counsel  acceptable to the holders of
         a  majority  in  principal  amount of the  Registrable  Securities  for
         compliance with securities or blue sky laws;

                  (3) the Company's printing, messenger, telephone and  delivery
         expenses;

                  (4)      fees and disbursements of counsel for the Company;

                  (5) fees and disbursements of all independent certified public
         accountants of the Company (including the expenses of any special audit
         necessary to satisfy the requirements of the Securities Act); and

                  (6) fees and expenses associated with any NASD filing required
         to be made in connection with the Registration Statement.

(all such expenses being herein called "Registration Expenses") will be borne by
the Company, regardless of whether the Registration Statement becomes effective.

         The Company will, in any event, pay its internal  expenses  (including,
without  limitation,  all salaries  and  expenses of its officers and  employees
performing  legal or accounting  duties),  the expense of any annual audit,  the
fees and expenses  incurred in connection  with the listing of the securities to
be registered on a securities exchange or the Nasdaq SmallCap Market.

                                       7
<PAGE>

6.       Indemnification and Contribution

         (a) Indemnification by the Company. The Company agrees to indemnify and
hold harmless each Holder of Registrable  Securities,  its officers,  directors,
employees and agents and each Person who controls such Holder within the meaning
of either  Section 15 of the  Securities  Act or Section 20 of the  Exchange Act
(each such person being  sometimes  hereinafter  referred to as an  "Indemnified
Holder") from and against all losses, claims, damages,  liabilities and expenses
(including  reasonable costs of investigation and legal expenses) arising out of
or based upon any untrue  statement  or alleged  untrue  statement of a material
fact contained in any  Registration  Statement or Prospectus or in any amendment
or supplement  thereto or in any  preliminary  prospectus,  or arising out of or
based upon any  omission or alleged  omission to state  therein a material  fact
required to be stated  therein or necessary to make the  statements  therein not
misleading;  provided,  however, that the Company will not be liable in any such
case to the  extent  that any  such  losses,  claims,  damages,  liabilities  or
expenses  arise out of or are based upon any untrue  statement or alleged untrue
statement  or  omission  or alleged  omission  thereof  based  upon  information
furnished  in writing to the Company by such Holder or its agent  expressly  for
use therein;  provided further, that the Company shall not be liable in any such
case to the  extent  that any such loss,  claim,  damage,  liability  or expense
arises out of or is based upon an untrue  statement or alleged untrue  statement
or omission or alleged  omission in the Prospectus,  if such untrue statement or
alleged untrue statement,  omission or alleged omission was completely corrected
in an amendment or supplement to the Prospectus and if, having  previously  been
furnished  by or on behalf of the Company  with copies of the  Prospectus  as so
amended or supplemented, such Holder thereafter fails to deliver such Prospectus
as so  amended  or  supplemented,  prior to or  concurrently  with the sale of a
Registrable Security to the person asserting such loss, claim, damage, liability
or expense who purchased such Registrable  Security which is the subject thereof
from such Holder.  This indemnity will be in addition to any liability which the
Company may otherwise have.

         If any action or proceeding  (including any governmental  investigation
or inquiry)  shall be brought or  asserted  against  any  Indemnified  Holder in
respect of which  indemnity  may be sought from the  Company,  such  Indemnified
Holder  shall  promptly  notify the Company in writing  (but the  omission to so
notify  the  Company  shall not  relieve  it of any  liability  that it may have
against any Indemnified  Holder otherwise than under this  subsection),  and the
Company shall assume the defense  thereof,  including the  employment of counsel
reasonably  satisfactory  to such  Indemnified  Holder  and the  payment  of all
expenses.  Indemnified  Holders  shall have the right,  collectively,  to employ
their own counsel in any such action and to participate in the defense  thereof,
but  the  fees  and  expenses  of  such  counsel  shall  be the  expense  of the
Indemnified  Holders  unless  (a) the  Company  has  agreed to pay such fees and
expenses  or (b) the  Company  shall have  failed to assume the  defense of such
action or proceeding and have failed to employ counsel  reasonably  satisfactory
to the  Indemnified  Holders in any such action or  proceeding  or (c) the named
parties to any such  action or  proceeding  (including  any  impleaded  parties)
include the Indemnified  Holders and the Company,  and the  Indemnified  Holders
shall have been advised by counsel that there may be one or more legal  defenses
available to the  Indemnified  Holders which are different from or additional to
those available to the Company (in which case, if the Indemnified Holders notify
the  Company  in  writing  that they  elect to employ  their own  counsel at the
expense  of the  Company,  the  Company  shall not have the right to assume  the

                                       8
<PAGE>


defense of such action or proceeding on behalf of the  Indemnified  Holders,  it
being  understood,  however,  that the Company shall not, in connection with any
one such action or proceeding or separate but  substantially  similar or related
actions or proceedings in the same jurisdiction  arising out of the same general
allegations or circumstances,  be liable for the reasonable fees and expenses of
more than one  separate  firm of  attorneys  (together  with  appropriate  local
counsel) at any time for the Indemnified  Holders which firm shall be designated
in writing by the  Indemnified  Holders  representing at least a majority of the
aggregate principal amount of the outstanding Registrable Securities).  Any such
fees and  expenses  payable  by the  Company  shall  be paid to the  Indemnified
Holders  entitled  thereto as incurred by the Indemnified  Holders.  The Company
shall not be liable for any settlement of any such action or proceeding effected
without its written  consent,  but if settled  with its written  consent,  or if
there be a final  judgment for the  plaintiff in any such action or  proceeding,
the Company agrees to indemnify and hold harmless the  Indemnified  Holders from
and against any loss or liability by reason of such settlement or judgment.

         (b) Indemnification by Holder of Registrable Securities. Each Holder of
Registrable  Securities  agrees to indemnify and hold harmless the Company,  its
respective  directors  and officers  and each  Person,  if any, who controls the
Company within the meaning of either Section 15 of the Securities Act or Section
20 of the Exchange Act to the same extent as the  foregoing  indemnity  from the
Company to such Holder,  but only with respect to  information  relating to such
Holder furnished in writing by such Holder expressly for use in any Registration
Statement  or  Prospectus,  or  any  amendment  or  supplement  thereto,  or any
preliminary  prospectus.  In case any  action  or  proceeding  shall be  brought
against  the  Company  or its  respective  directors  or  officers  or any  such
controlling person, in respect of which indemnity may be sought against a Holder
of  Registrable  Securities,  such Holder shall have the rights and duties given
the  Company,  and the Company or its  respective  directors or officers or such
controlling  person shall have the rights and duties given to each holder by the
preceding  paragraph.  In  no  event  shall  the  liability  of  any  Holder  of
Registrable  Securities hereunder be greater in amount than the dollar amount of
the proceeds received by such Holder upon the sale of the Registrable Securities
giving rise to such indemnification obligation.

         (c) Contribution. If the indemnification provided for in this Section 6
is unavailable to an indemnified party under Section 6(a) or Section 6(b) hereof
(other than by reason of  exceptions  provided in those  Sections) in respect of
any losses, claims,  damages,  liabilities or expenses referred to therein, then
each applicable  indemnifying  party, in lieu of indemnifying  such  indemnified
party,  shall contribute to the amount paid or payable by such indemnified party
as a result of such losses,  claims,  damages,  liabilities or expenses,  (i) in
such proportion as is appropriate to reflect the relative  benefits  received by
the Company from the sale of the Preferred  Shares to Purchaser  pursuant to the
Purchase  Agreement  on the one hand and each Holder of  Registrable  Securities
from the offering of the  Registrable  Securities  by such Holder,  on the other
hand, or (ii) if the allocation provided by clause (i) above is not permitted by
applicable  law, in such  proportion as is  appropriate  to reflect not only the
relative benefits referred to in clause (i) above but also the relative fault of
the Company on the one hand and each  Holder of  Registrable  Securities  on the
other in  connection  with the  statements  or omissions  that  resulted in such
losses, claims, damages, or liabilities, as well as the other relevant equitable
considerations.  The relative  benefits  received by the Company on the one hand
and each Holder of Registrable  Securities on the other shall be deemed to be in


                                       9
<PAGE>


the same  proportion  as the  aggregate  amount paid by Purchaser to the Company
pursuant to the Purchase Agreement for the Registrable  Securities  purchased by
such Holder that were sold pursuant to the  Registration  Statement bears to the
difference  (the  "Difference")  between  the amount  such  Holder  paid for the
Registrable Securities that were sold pursuant to the Registration Statement and
the amount  received by such Holder from such sale.  The relative fault shall be
determined by reference  to, among other  things,  whether the untrue or alleged
untrue statement of a material fact or the omission or alleged omission to state
a material fact relates to information supplied by the Company or the particular
Holder and the parties'  relative intent,  knowledge,  access to information and
opportunity to correct or prevent such untrue statement or omission. The Company
and the Holders of  Registrable  Securities  agree that it would not be just and
equitable if contributions pursuant to this subsection (c) were to be determined
by pro rata  allocation or by any other method of allocation  that does not take
account of the equitable consideration referred to in the first sentence of this
subsection  (c).  The  amount  paid by an  indemnified  party as a result of the
losses, claims, damages or liabilities referred to in the first sentence of this
subsection (c) shall be deemed to include any legal or other expenses reasonably
incurred by such indemnified party in connection with investigation or defending
against  any  action  or  claim  that is the  subject  of this  subsection  (c).
Notwithstanding   the  provisions  of  this   subsection  (c),  each  Holder  of
Registrable  Securities shall not be required to contribute any amount in excess
of the amount by which the  Difference  exceeds the amount of any  damages  that
such  Holder has  otherwise  been  required  to pay by reason of such  untrue or
alleged untrue  statement or omission or alleged  omission.  No person guilty of
fraudulent  misrepresentation  (within  the  meaning  of  Section  11(f)  of the
Securities Act),  shall be entitled to contribution  from any person who was not
guilty of such fraudulent misrepresentation.

7.       Rule 144 and Rule 144A

         For so long as the Company is subject to the reporting  requirements of
Section 13 or 15 of the Exchange  Act, the Company  covenants  that it will file
the  reports  required  to be filed by it under the  Securities  Act and Section
13(a) or 15(d) of the Exchange Act and the rules and regulations  adopted by the
SEC thereunder.  If the Company is not subject to the reporting  requirements of
Section 13 or 15 of the Exchange  Act, the Company also  covenants  that it will
provide  the  information   required  pursuant  to  Rule  144A(d)(4)  under  the
Securities  Act upon the request of any Holder of Registrable  Securities  which
continue to be  "restricted  securities"  within the  meaning of Rule  144(a)(3)
under the  Securities  Act and it will take such further action as any holder of
such Registrable  Securities may reasonably request,  all to the extent required
from  time to time to enable  such  holder  to sell its  Registrable  Securities
without  registration  under the  Securities  Act within the  limitation  of the
exemptions  provided by (a) Rule 144 under the Securities  Act, as such Rule may
be amended  from time to time,  so long as such  provision  does not require the
public  filing of  information  relating to the Company which the Company is not
otherwise required to file, (b) Rule 144A under the Securities Act, as such Rule
may be  amended  from  time to  time,  or (c)  any  similar  rule or  regulation
hereafter  adopted  by the SEC that  does  not  require  the  public  filing  of
information  relating  to  the  Company.  Upon  the  request  of any  Holder  of
Registrable  Securities,  the  Company  will  deliver  to such  Holder a written
statement as to whether it has complied with such requirements.

                                       10
<PAGE>

8.       Miscellaneous

         (a) No  Inconsistent  Agreements.  The Company will not on or after the
date of this Agreement enter into any agreement with respect to their securities
which is  inconsistent  with the rights  granted to the  Holders of  Registrable
Securities in this Agreement or otherwise  conflicts with the provisions hereof.
The rights granted to the Holders of Registrable  Securities hereunder do not in
any way conflict with and are not  inconsistent  with the rights  granted to the
holders of the Company's securities under any such agreements.

         (b) Adjustments Affecting Registrable Securities.  The Company will not
take any action,  or permit any change to occur, with respect to the Registrable
Securities   which  would  adversely  affect  the  ability  of  the  Holders  of
Registrable  Securities to include such Registrable Securities in a registration
undertaken pursuant to this Agreement.

         (c) Amendments and Waivers. The provisions of this Agreement, including
the provisions of this sentence,  may not be amended,  modified or supplemented,
and waivers or  consents to  departures  from the  provisions  hereof may not be
given  unless the  Company  has  obtained  the  written  consent of Holders of a
majority of the Registrable Securities.

         (d) Notices. All notices,  requests,  consents and other communications
hereunder  shall be by  telecopier,  with a copy  being  mailed by a  nationally
recognized  overnight express courier, and shall be deemed given when receipt is
acknowledged  by  transmit  confirmation  report,  and  shall  be  delivered  as
addressed as follows:

                  (1) if to the Purchaser,  at the most current address given by
         the Purchaser to the Company in accordance  with the provisions of this
         Section 8(d), which address  initially is as set forth on the signature
         page hereto;

                  (2) if to a Holder of Registrable  Securities,  at its address
         of record as indicated on the books of the transfer agent and registrar
         for the Registrable Securities; and

                  (3) if to the  Company,  initially at its address set forth in
         Section  10 of the  Purchase  Agreement  and  thereafter  at such other
         addresses,  notice of which is given in accordance  with the provisions
         of this Section 8(d).

         (e) Successors and Assigns.  This Agreement  shall inure to the benefit
of and be  binding  upon the  successors  and  assigns  of each of the  parties,
including  without  limitation  and without the need for an express  assignment,
subsequent Holders of Registrable Securities.

         (f)  Counterparts.  This  Agreement  may be  executed  in any number of
counterparts and by the parties hereto in separate  counterparts,  each of which
when so  executed  shall be  deemed  to be an  original  and all of which  taken
together shall constitute one and the same agreement.

                                       11
<PAGE>

         (g) Headings.  The headings in this  Agreement are for  convenience  of
reference only and shall not limit or otherwise affect the meaning hereof.

         (h) GOVERNING LAW. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN
ACCORDANCE  WITH THE LAWS OF THE  STATE OF NEW YORK  (WITHOUT  REFERENCE  TO ITS
RULES AS TO  CONFLICTS  OF LAW) AND THE  FEDERAL  LAW OF THE  UNITED  STATES  OF
AMERICA.

         (i)  Severability.  In the event that any one or more of the provisions
contained  herein,  or the  application  thereof  in any  circumstance,  is held
invalid, illegal or unenforceable,  the validity, legality and enforceability of
any such  provision  in every  other  respect  and of the  remaining  provisions
contained herein shall not be affected or impaired thereby.

         (j) Entire  Agreement.  This  Agreement is intended by the parties as a
final  expression of their agreement and intended to be a complete and exclusive
statement of the agreement and understanding of the parties hereto in respect of
the  subject  matter  contained  herein.  There are no  restrictions,  promises,
warranties  or  undertakings,  other than those set forth or  referred to herein
with respect to the  registration  rights granted by the Company with respect to
the  securities  sold  pursuant  to  the  Purchase  Agreement.   This  Agreement
supersedes  all prior  agreements  and  understandings  between the parties with
respect to such subject matter.

         (k)  Calculation of Majority.  For purposes of determining  whether the
Holders of a majority of the  Registrable  Securities have taken action pursuant
thereto,  any Preferred Shares and Warrants then outstanding  shall be deemed to
have been converted into Underlying Common Shares, which shares shall be treated
as outstanding for purposes hereof.



                                       12
<PAGE>


         IN WITNESS WHEREOF,  the parties have executed this Agreement as of the
date first written above.

                                        DERMA SCIENCES, INC.


                                        By: _______________________________
                                             Edward J. Quilty
                                        Chairman


                                        Print or Type:

                                        Name of Purchaser
                                        (Individual or Institution):


                                        -----------------------------------

                                        Name of Individualrepresenting 
                                        Purchaser (if an Institution):


                                        -----------------------------------

                                        Title of Individual representing 
                                        Purchaser (if an Institution):


                                        -----------------------------------


                                        Signature by:

                                        Individual Purchaser or Individual
                                        representing Purchaser:


                                        -----------------------------------

                                        Address: ___________________________

                                        Telephone: _________________________

                                        Telecopier: _________________________




                   CERTIFICATE OF DESIGNATIONS, VOTING POWERS,

                             PREFERENCES AND RIGHTS

                                       OF

                          THE SERIES OF PREFERRED STOCK

                                       OF

                              DERMA SCIENCES, INC.

                                TO BE DESIGNATED

                      SERIES A CONVERTIBLE PREFERRED STOCK


         Pursuant  to the  Pennsylvania  Business  Corporation  Law of 1988,  I,
Edward J. Quilty, Chairman of the Board of Derma Sciences,  Inc., a Pennsylvania
corporation (the "Corporation"), hereby certify that the following is a true and
correct  copy  of a  resolution  duly  adopted  by the  Corporation's  Board  of
Directors at a meeting held on December 10, 1997,  at which a quorum was present
and  acting  throughout,  and  that  said  resolution  has not been  amended  or
rescinded and is in full force and effect at the date hereof:

         RESOLVED,  that pursuant to the authority  expressly granted and vested
in the Board of Directors of the  Corporation by the  Corporation's  Articles of
Incorporation,  as  amended to date,  the Board of  Directors  hereby  creates a
series of preferred  stock of the  Corporation,  par value $.01 per share, to be
designated  "Series A  Convertible  Preferred  Stock"  (the  "Series A Preferred
Stock")  and to  consist  of [ shares],  and  hereby  fixes the  voting  powers,
designations,  preferences and relative, participating, optional or other rights
and the  qualifications,  limitations or restrictions  thereon,  of the Series A
Preferred Stock, as follows:

1.   Voting Rights. The holders of Series A Preferred Stock shall have the right
     to vote,  together with the holders of all the outstanding shares of Common
     Stock and not by classes, except as otherwise required by Pennsylvania law,
     on all matters on which holders of Common Stock are entitled to vote.  Each
     holder of shares of Series A  Preferred  Stock shall have the right to cast
     one vote for each share.

2.   Liquidation   or   Dissolution.   Subject  to  the  prior   rights  of  the
     Corporation's  creditors and holders of  securities  senior to the Series A
     Preferred Stock in respect of distributions  upon liquidation,  dissolution
     or  winding-up  of the  Corporation,  in the  event  of  the  voluntary  or
     involuntary liquidation,  dissolution or winding-up of the Corporation, the
     holders of Series A  Preferred  Stock  shall be  entitled  to  receive  the
     purchase  price per share (the  "Liquidation  Preference"),  together  with
     accrued and unpaid dividends  payable thereon to the date fixed for payment
     of such  distribution,  if any,  which shall be payable on a pro rata basis
     among holders of Preferred and Common Stock,  all of which shall be paid in
     cash.  If, upon any such  liquidation,  dissolution  or  winding-up  of the


                                      
<PAGE>


     Corporation,  the  assets  distributable  among  the  holders  of  Series A
     Preferred  Stock (and any series of preferred  stock ranking in parity with
     the Series A Preferred Stock in respect of distributions  upon liquidation,
     dissolution  or winding-up of the  Corporation)  shall be  insufficient  to
     permit the  payment  in full to such  holders  of the  preferential  amount
     payable to such holders determined as aforesaid, then the holders of Series
     A  Preferred   Stock  will  share  ratably  in  any   distribution  of  the
     Corporation's  assets in proportion to the respective  preferential amounts
     that  would have been  payable if such  assets  were  sufficient  to permit
     payment in full of all such  amounts.  After  payment of the full amount of
     the  liquidating  distribution  to which they are entitled,  the holders of
     Series A Preferred Stock will not be entitled to any further  participation
     in any distribution of assets by the  Corporation.  Under this Section 2, a
     distribution  of  assets in any  dissolution,  winding-up,  liquidation  or
     reorganization  shall  include  (a)  any  consolidation  or  merger  of the
     Corporation with or into any other  corporation in which the Corporation is
     not the surviving  corporation,  (b) a sale or other  disposition of all or
     substantially  all of the  Corporation's  assets in consideration  for cash
     and/or the issuance of equity securities of another  corporation,  or (c) a
     Change of Control of the Company.  Under this Section 2, a distribution  of
     assets in any dissolution,  winding-up, liquidation or reorganization shall
     not include any dissolution,  liquidation,  winding-up or reorganization of
     the  Corporation  immediately  followed by  reincorporation  of a successor
     corporation,  provided  that the  dissolution,  liquidation,  winding-up or
     reorganization  does not amend,  alter, or change the preferences or rights
     of the  Series A  Preferred  Stock or the  qualifications,  limitations  or
     restrictions  thereof  in a manner  that  adversely  affects  the  Series A
     Preferred Stock.

3.   Conversion Rights.

     (a)  Conversion  of  Series A  Preferred  Stock.  Each  share  of  Series A
          Preferred  Stock  shall be  convertible  at the  option of the  holder
          thereof into one fully paid and non-assessable  share of Common Stock,
          ("Conversion Share(s)") subject to the provisions set forth herein.

     (b)  Mechanics  of  Conversion.  The  holder  of any  shares  of  Series  A
          Preferred  Stock  may  exercise  the  conversion  right as to any part
          thereof by  delivering  to the  Corporation  during  regular  business
          hours, at the office of the Corporation at 214 Carnegie Center,  Suite
          100,  Princeton,  New Jersey  08540,  a conversion  notice in the form
          attached  to the  purchase  agreement  pursuant  to which the Series A
          Preferred Stock is issued (the  "Conversion  Notice").  The Conversion
          Notice shall state that the holder elects to convert its share subject
          to  applicable   securities   laws,  (i)  the  name(s)  in  which  the
          certificate(s) representing the Conversion Shares to which such holder
          is entitled are to be issued,  and (ii) the telecopier number to which
          the  Corporation  shall  telecopy its  confirmation  described  below.
          Notice  given by  telecopier  to  telecopier  number  (609)  452-0880,
          Attention:  Edward J. Quilty,  shall be deemed  notice for purposes of
          this paragraph and shall be deemed given when receipt is  acknowledged
          by  transmit  confirmation  report.  Immediately  upon  receipt of any
          Conversion  Notice,  the  Corporation  shall,  by telecopier,  confirm
          receipt  thereof at the  telecopier  number  included  thereon,  which
          confirmation  shall set forth the  number of  Conversion  Shares to be
          issued  by  the  Corporation  as a  result  of  such  conversion.  The
          Conversion Notice shall be deemed accepted by the Corporation provided
          the  holder  surrenders,  or  causes  any  agent  for  the  holder  to
          surrender,  the  certificate(s) for the Series A Preferred Stock to be
          converted,  duly endorsed or assigned in blank or to the  Corporation,
          at any location set forth above,  within seven (7) business days after
          delivery of the Conversion  Notice.  Provided that the  certificate(s)
          are  delivered  in  accordance  with  the  preceding   sentence,   the


                                       2
<PAGE>

          conversion  shall  be  deemed  to have  been  effected  on the date of
          delivery  of the  Conversion  Notice by  telecopier,  and such date is
          referred to herein as the "Conversion Date." Within three (3) business
          days of receipt by the Corporation of the certificate(s)  representing
          the Series A  Preferred  Stock,  the  Corporation  shall issue to such
          holder a certificate or certificates  representing  the number of full
          Conversion Shares which such holder is entitled to receive. Unless (i)
          such  Conversion  Shares  have been held long  enough to  satisfy  the
          holding  period set forth in Rule 144(k) (or any successor  provision)
          promulgated  under the Securities  Act, (ii) such shares become freely
          tradeable  pursuant to another  exemption under the Securities Act, or
          (iii) the  converting  holder  purchased  such  shares  pursuant  to a
          current prospectus under an effective  registration statement covering
          the purchase and sale of such shares, the certificate(s)  representing
          the Conversion Shares will bear the following legend:

                           THE SHARES  REPRESENTED BY THIS  CERTIFICATE HAVE NOT
                           BEEN REGISTERED  UNDER THE SECURITIES ACT OF 1933, AS
                           AMENDED. THE SHARES HAVE BEEN ACQUIRED FOR INVESTMENT
                           AND MAY NOT BE SOLD,  TRANSFERRED  OR ASSIGNED IN THE
                           ABSENCE OF EITHER AN EFFECTIVE REGISTRATION STATEMENT
                           FOR THESE SHARES UNDER THE SECURITIES ACT OF 1933, AS
                           AMENDED,  OR AN OPINION OF COUNSEL THAT  REGISTRATION
                           IS NOT  REQUIRED  UNDER  SAID ACT.  THESE  SHARES ARE
                           SUBJECT TO CERTAIN  REGISTRATION  RIGHTS AS SET FORTH
                           IN A REGISTRATION  RIGHTS AGREEMENT,  A COPY OF WHICH
                           MAY BE OBTAINED FROM THE CORPORATION.

          If the Registration  Statement as hereinafter  defined shall have been
          declared  effective by the  Securities  and Exchange  Commission,  the
          certificate(s)   evidencing  the  Conversion   Shares  will  bear  the
          following legend:

                           THE SHARES  REPRESENTED BY THIS CERTIFICATE HAVE BEEN
                           REGISTERED  UNDER  THE  SECURITIES  ACT OF  1933,  AS
                           AMENDED.  THE  SHARES  MAY BE  SOLD  PURSUANT  TO THE
                           REGISTRATION   STATEMENT  PROVIDED  THAT  THE  HOLDER
                           COMPLIES WITH THE  PROSPECTUS  DELIVERY  REQUIREMENTS
                           UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND THE
                           SALE IS IN COMPLIANCE  WITH THE PLAN OF  DISTRIBUTION
                           AS SET  FORTH IN THE  PROSPECTUS.  THESE  SHARES  ARE
                           SUBJECT TO CERTAIN  REGISTRATION  RIGHTS AS SET FORTH
                           IN A REGISTRATION  RIGHTS AGREEMENT,  A COPY OF WHICH
                           MAY BE OBTAINED FROM THE CORPORATION.

          The person in whose name the  certificate(s) for the Conversion Shares
          are to be  issued  shall be  deemed to have  become a  stockholder  of
          record on the applicable  Conversion Date unless the transfer books of
          the  Corporation  are  closed on that date,  in which  event he or she
          shall be deemed  to have  become a  stockholder  of record on the next
          succeeding  date  on  which  the  transfer  books  are  open,  but the
          Conversion  Ratio shall be that in effect on the Conversion Date. Upon


                                       3
<PAGE>

          conversion of only a portion of the number of whole shares  covered by
          a  certificate   representing  shares  of  Series  A  Preferred  Stock
          surrendered for conversion, the Corporation shall issue and deliver to
          or  upon  the  written  order  of the  holder  of the  certificate  so
          surrendered for conversion,  at the expense of the Corporation,  a new
          certificate  covering the number of shares of Series A Preferred Stock
          representing   the   unconverted   portion  of  the   certificate   so
          surrendered,  which new certificate  shall entitle in all respects the
          holder thereof to the rights of Series A Preferred  Stock  represented
          thereby to the same extent as if the certificate  theretofore covering
          such unconverted shares had not been surrendered for conversion.

     (c)  Fractional Shares. No fractional shares of Common Stock or scrip shall
          be issued upon  conversion of shares of Series A Preferred  Stock.  If
          more than one share of Series A Preferred  Stock shall be  surrendered
          for conversion at any one time by the same holder,  the number of full
          shares of Common  Stock  issuable  upon  conversion  thereof  shall be
          computed  on the basis of the  aggregate  number of shares of Series A
          Preferred  Stock so surrendered.  Instead of any fractional  shares of
          Common Stock which would  otherwise be issuable upon conversion of any
          shares of Series A Preferred Stock,  the Corporation  shall pay a cash
          adjustment  in  respect  of  such  fractional  interest  in an  amount
          determined on the basis of the then Current  Market Price per share of
          Common Stock. Fractional interests shall not be entitled to dividends,
          and the  holders  thereof  shall  not be  entitled  to any  rights  as
          stockholders   of  the  Corporation  in  respect  of  such  fractional
          interests.

     (d)  Adjustments  to  Conversion  Ratio for Certain  Events.  The number of
          Conversion  Shares  underlying each Preferred  Share (the  "Conversion
          Ratio") shall be subject to adjustment  from time to time as set forth
          in this subsection (d).

          (i)  In case at any time, or from time to time, the Corporation shall:
               (A) take a record  of the  holders  of its  Common  Stock for the
               purpose  of  entitling  them  to  receive  a  dividend  or  other
               distribution  payable in shares of capital  stock;  (B) subdivide
               its  outstanding  shares of Common Stock into a larger  number of
               shares; (C) combine its outstanding shares of Common Stock into a
               smaller  number of shares;  or (D) issue by  reclassification  or
               recapitalization of its Common Stock any other class or series of
               shares of the Corporation (including any such reclassification or
               recapitalization  in connection with a consolidation or merger in
               which  the  Corporation  is  the  continuing  corporation),   the
               Conversion  Ratio in  effect at the time of the  record  date for
               such  dividend  or of the  effective  date of  such  subdivision,
               combination,   reclassification  or  recapitalization   shall  be
               proportionately  adjusted  so that  the  holder  of any  Series A
               Preferred Stock  surrendered for conversion after such time shall
               be entitled to receive  the  aggregate  number and kind of shares
               which,  if such  Series A  Preferred  Stock  had  been  converted
               immediately  prior to such time,  such holder would have owned or
               have been  entitled to  receive.  Such  adjustment  shall be made
               successively  whenever any event listed above shall occur. In the
               event that such  dividend  or  distribution  is not so made,  the
               Conversion  Ratio shall  again be  adjusted to be the  Conversion
               Ratio  which  would then be in effect if such record date has not
               been fixed.

                                       4
<PAGE>

          (ii) In case at any time, or from time to time, the Corporation  shall
               (except as  hereinafter  provided)  issue or sell any  Additional
               Shares of Common  Stock for a  consideration  per share of Common
               Stock less than the Current  Market  Price,  then the  Conversion
               Ratio shall,  on the date  specified  below for  determining  the
               Current  Market Price,  be adjusted to that number  determined by
               multiplying the Conversion Ratio in effect  immediately  prior to
               such adjustment by a fraction the numerator of which shall be the
               number of shares of Common Stock outstanding immediately prior to
               the issuance of the Additional  Shares of Common Stock (including
               shares deemed to have been issued pursuant to subsection (d)(iii)
               below)  plus the  number  of shares  of  Common  Stock  which the
               aggregate  consideration  for the total number of such Additional
               Shares of Common  Stock so issued  would  purchase at the Current
               Market Price, and the denominator of which shall be the number of
               shares  of  Common  Stock  outstanding  immediately  prior to the
               issuance  of such  Additional  Shares  of Common  Stock  plus the
               number  of such  Additional  Shares  of  Common  Stock so  issued
               (including   shares  deemed  to  have  been  issued  pursuant  to
               subsection  (d)(iii) below).  For the purposes of this subsection
               (d)(ii),  the date as of which the Current Market Price per share
               of Common Stock shall be computed shall be the earlier of (x) the
               date on which the Corporation  shall enter into a legally binding
               contract  for the issuance or sale of such  Additional  Shares of
               Common  Stock  or (y) the  date of the  actual  issuance  of such
               Additional  Shares  of  Common  Stock.  The  provisions  of  this
               subsection  (d)(ii) shall not apply to any issuance of Additional
               Shares of Common Stock for which an adjustment is provided  under
               subsection  (i) hereof.  No  adjustment  shall be made under this
               subsection  (d)(ii) upon the issuance of any Additional Shares of
               Common  Stock which are issued  pursuant  to the  exercise of any
               warrants or other  subscription or purchase rights or pursuant to
               the  exercise  of  any  conversion  or  exchange  rights  in  any
               Convertible  Securities,  if any such adjustment shall previously
               have been made upon the issuance of such warrants or other rights
               or upon the issuance of such Convertible  Securities (or upon the
               issuance of any  warrant or other  rights  therefor)  pursuant to
               subsection   (d)(iii)   hereof.   Adjustments   shall   be   made
               successively  whenever such an issuance of  Additional  Shares of
               Common  Stock  shall  occur.  In the event  that such  Additional
               Shares of Common Stock are not so issued or sold,  the Conversion
               Ratio shall again be  adjusted to be the  Conversion  Ratio which
               would then be in effect if such issuance had not occurred.

          (iii)In case at any time, or from time to time, the Corporation  shall
               take a record of the holders of the Common  Stock for the purpose
               of  entitling  them  to  receive  a  distribution  of,  or  shall
               otherwise issue, any warrants or other rights to subscribe for or
               purchase any Additional Shares of Common Stock or any Convertible
               Securities and the  consideration  per share for which Additional
               Shares of Common  Stock may at any time  thereafter  be  issuable
               pursuant  to such  warrants  or other  rights or  pursuant to the
               terms  of such  Convertible  Securities  shall  be less  than the
               Current  Market  Price,  then the  Conversion  Ratio  immediately
               thereafter  shall be adjusted as provided in  subsection  (d)(ii)
               hereof on the basis  that (a) the  maximum  number of  Additional
               Shares of Common Stock issuable  pursuant to all such warrants or
               other rights or necessary to effect the conversion or exchange of


                                       5
<PAGE>

               all such  Convertible  Securities  shall be  deemed  to have been
               issued as of the date for the determination of the Current Market
               Price per share of Common Stock as hereinafter provided,  and (b)
               the aggregate consideration for such maximum number of Additional
               Shares  of  Common  Stock  shall  be  deemed  to be  the  minimum
               consideration  received and receivable by the Corporation for the
               issuance of such  Additional  Shares of Common Stock  pursuant to
               such  warrants  or other  rights or pursuant to the terms of such
               Convertible  Securities.  For the  purposes  of  this  subsection
               (d)(iii), the date as of which the Current Market Price per share
               of Common  Stock shall be computed  shall be the  earliest of (i)
               the date on which  the  Corporation  shall  take a record  of the
               holders of its Common Stock for the purpose of entitling  them to
               receive any such warrants or other rights, (ii) the date on which
               the Corporation  shall enter into a legally binding  contract for
               the  issuance of such  warrants or other rights or (iii) the date
               of  actual  issuance  of such  warrants  or  other  rights.  Such
               reduction shall be made successively  whenever such a record date
               is fixed.  In the event that such rights or  warrants  are not so
               issued or (if issued) to the extent not exercised, the Conversion
               Ratio shall again be adjusted to be the Conversion  Ratio, as the
               case may be,  which  would then be in effect if such  record date
               had not been fixed or such unexercised rights or warrants had not
               been issued.

          (iv) In case at any time, or from time to time, the Corporation  shall
               take a record of the holders of its Common  Stock for the purpose
               of  entitling  them to receive a  distribution,  by  dividend  or
               otherwise,  of evidences of its indebtedness or assets (including
               securities,  but  excluding  (x)  any  dividend  or  distribution
               referred to in  subsection  (d)(i) hereof and (y) any dividend or
               distribution paid in cash out of funds legally available therefor
               of the Corporation),  then in each such case the Conversion Ratio
               in  effect  after  such  record  date  shall  be   determined  by
               multiplying the Conversion Ratio, in effect  immediately prior to
               such record date by a fraction,  of which the numerator  shall be
               the total number of outstanding shares of Common Stock multiplied
               by the Current  Market Price on such record  date,  less the fair
               market  value (as  determined  by the Board of  Directors  of the
               Corporation,  whose  determination  shall be  conclusive)  of the
               portion  of the  assets or  evidences  of  indebtedness  so to be
               distributed,  and of which  the  denominator  shall be the  total
               number of outstanding  shares of Common Stock  multiplied by such
               Current Market Price.  Such adjustment shall be made successively
               whenever  such a record  date is fixed.  In the  event  that such
               distribution is not so made, the Conversion  Ratio shall again be
               adjusted to be the Conversion Ratio which would then be in effect
               if such record date had not been fixed.

          (v)  No adjustment in the  Conversion  Ratio shall be required  unless
               such adjustment would require an increase or decrease of at least
               one percent (1%) in such  Conversion  Ratio;  provided,  however,
               that any adjustment which by reason of this paragraph (vi) is not
               required  to be made  shall be  carried  forward  and taken  into
               account in any subsequent adjustment. All calculations under this
               subsection  (d)  shall  be  made  to the  nearest  cent or to the
               nearest 1/100 of a share, as the case may be.

                                       6
<PAGE>

     (e)  No  Impairment.   The  Corporation  will  not,  by  amendment  of  its
          Certificate of Incorporation or through any  reorganization,  transfer
          of  assets,  consolidation,  merger,  dissolution,  issue  or  sale of
          securities or any other voluntary  action,  avoid or seek to avoid the
          observance  or  performance  of any of the  terms  to be  observed  or
          performed hereunder by the Corporation,  but will at all times in good
          faith assist in the carrying out of all the provisions of this Section
          3 and in the  taking  of  all  such  action  as  may be  necessary  or
          appropriate in order to protect the  conversion  rights of the holders
          of the Series A Preferred Stock against impairment.

     (f)  Notice Provisions.

          (i)  Whenever  the  Conversion  Ratio  shall be  adjusted  pursuant to
               subsection (d) hereof,  the Corporation  shall forthwith obtain a
               certificate signed by the Corporation's  chief financial officer,
               setting  forth,  in reasonable  detail,  the event  requiring the
               adjustment and the method by which such adjustment was calculated
               (including a description of the basis on which the  Corporation's
               independent public  accountants  determined the fair value of any
               evidences of indebtedness,  shares of stock,  other securities or
               property or assets or warrants or other  subscription or purchase
               rights referred to in subsections  (d)(ii) through (d)(v) hereof)
               and  specifying  the new  Conversion  Ratio  and (if  applicable)
               describing  the  amount  and kind of  common  stock,  securities,
               property or assets or cash which may be received upon  conversion
               of the Series A  Preferred  Stock,  after  giving  effect to such
               adjustment. The Corporation shall promptly cause a signed copy of
               such  certificate  to be  delivered  to each  holder  of Series A
               Preferred Stock.

          (ii) In case the  Corporation  shall  propose (a) to pay any  dividend
               payable in stock of any class to the holders of its Common  Stock
               or to make any other  distribution  to the  holders of its Common
               Stock,  (b) to offer to the holders of its Common Stock rights to
               subscribe  for  or to  purchase  any  Convertible  Securities  or
               Additional Shares of Common Stock or shares of stock of any class
               or any other  securities,  rights or  options,  (c) to effect any
               reclassification    of   its   Common   Stock   (other   than   a
               reclassification involving only the subdivision or combination of
               outstanding  shares of Common  Stock),  (d) to effect any capital
               reorganization, (e) to effect any consolidation,  merger or sale,
               transfer or other  distribution of all or  substantially  all its
               property,  assets or business,  or (f) to effect the liquidation,
               dissolution or winding-up of the  Corporation,  then in each such
               case,  the  Corporation  shall  give to each  holder  of Series A
               Preferred  Stock a notice of such  proposed  action,  which shall
               specify  the  date  on  which a  record  is to be  taken  for the
               purposes of such stock dividend,  distribution or rights,  or the
               date   on   which    such    reclassification,    reorganization,
               consolidation, merger, sale, transfer, disposition,  liquidation,
               dissolution  or  winding-up  is to take  place  and  the  date of
               participation therein by the holders of Common Stock, if any such
               date is to be fixed,  and shall  also set forth  such  facts with
               respect thereto as shall be reasonably  necessary to indicate the
               effect of such  action  on the  Common  Stock and the  Conversion
               Ratio  after  giving  effect  to any  adjustment  which  will  be
               required  as a result of such  action.  Such  notice  shall be so
               given in the case of any  action  covered  by (a) or (b) above at
               least 20 days prior to the record date for determining holders of


                                       7
<PAGE>

               the Common  Stock for purposes of such action and, in the case of
               any other such action,  at least 20 days prior to the date of the
               taking  of such  proposed  action  or the  date of  participation
               therein by the holders of Common  Stock,  whichever  shall be the
               earlier.

     (g)  Treasury Stock. The sale or other  disposition of any issued shares of
          Common  Stock owned or held by or for the  account of the  Corporation
          shall be deemed an issuance  thereof for  purposes of  subsection  (d)
          hereof,  but until so  issued  such  shares  shall not be deemed to be
          outstanding.

     (h)  Computation of Consideration. To the extent that any Additional Shares
          of Common Stock or any Convertible Securities or any warrants or other
          rights to subscribe  for or purchase any  Additional  Shares of Common
          Stock  or  any  Convertible  Securities  shall  be  issued  for a cash
          consideration,  the consideration received by the Corporation therefor
          shall  be  deemed  to be  the  amount  of  the  cash  received  by the
          Corporation therefor, or, if such Additional Shares of Common Stock or
          Convertible   Securities   are   offered   by  the   Corporation   for
          subscription, the subscription price, or, if such Additional Shares of
          Common Stock or  Convertible  Securities are sold to  underwriters  or
          dealers  for public  offering  without a  subscription  offering,  the
          initial public  offering price, in any such case excluding any amounts
          paid or  receivable  for  accrued  interest or accrued  dividends  and
          without deduction of any  compensation,  discounts or expenses paid or
          incurred  by  the  Corporation  for  and in the  underwriting  of,  or
          otherwise in connection  with, the issue  thereof.  To the extent that
          such  issuance  shall be for a  consideration  other than cash,  then,
          except as herein  otherwise  expressly  provided,  the  amount of such
          consideration   shall  be  deemed  to  be  the  fair   value  of  such
          consideration  at the time of such issuance as determined by the Board
          of Directors of the Corporation.  The consideration for any Additional
          Shares of Common  Stock  issuable  pursuant  to any  warrants or other
          rights  to   subscribe   for  or  purchase   the  same  shall  be  the
          consideration received by the Corporation for issuing such warrants or
          other  rights,  plus  the  additional  consideration  payable  to  the
          Corporation  upon the exercise of such warrants or other  rights.  The
          consideration  for any  Additional  Shares  of Common  Stock  issuable
          pursuant  to the  terms  of any  Convertible  Securities  shall be the
          consideration  received by the Corporation for issuing any warrants or
          other rights to subscribe for or purchase such Convertible Securities,
          plus the  consideration  paid or payable to the Corporation in respect
          of the subscription  for or purchase of such  Convertible  Securities,
          plus the additional consideration,  if any, payable to the Corporation
          upon the  exercise  of the right of  conversion  or  exchange  in such
          Convertible  Securities.  In case of the  issuance  at any time of any
          Additional Shares of Common Stock or Convertible Securities in payment
          or  satisfaction  of any  dividend  upon any class of stock other than
          Common  Stock or in  payment  of any debt,  the  Corporation  shall be
          deemed to have received for such Additional  Shares of Common Stock or
          Convertible  Securities  a  consideration  equal to the amount of such
          dividend or debt so paid or satisfied.

     (i)  Fractional  Interests.  In computing adjustments under this Section 3,
          fractional  interests  in Common  Stock shall be taken into account to
          the nearest one-hundredth of a share.

     (j)  Antidilution  Provisions.  No adjustment  shall be made as a result of


                                       8
<PAGE>

          any  increase  in the  number of  Additional  Shares  of Common  Stock
          issuable  or  any  decrease  in the  consideration  payable  upon  any
          issuance  of  Additional  Shares  of  Common  Stock,  pursuant  to any
          provisions   intended  solely  to  avoid  dilution  contained  in  any
          warrants, rights or Convertible Securities.

     (k)  When Adjustment Not Required.

          (i)  If the  Corporation  shall  take a record of the  holders  of its
               Common  Stock for the  purpose  of  entitling  them to  receive a
               dividend or  distribution  or subscription or purchase rights and
               shall,  thereafter and before the  distribution  to  stockholders
               thereof,  legally  abandon  its  plan  to  pay  or  deliver  such
               dividend,  distribution,  subscription or purchase  rights,  then
               thereafter  no  adjustment  shall be  required  by  reason of the
               taking of such record and any such adjustment  previously made in
               respect thereof shall be rescinded and annulled.

          (ii) If the Corporation declares or makes any dividend or distribution
               with respect to Common Stock,  other than regular cash  dividends
               or dividends  payable solely in shares of Common Stock,  and each
               holder  of  Series  A  Preferred  Stock   concurrently   receives
               dividends or  distributions  equal in amount and in the same kind
               of property (whether cash,  securities or other property) as such
               holder  would be  entitled  to receive if all of the  outstanding
               Series A Preferred  Stock were  converted into Common Stock as of
               the record date of such dividend or distribution  with respect to
               Common Stock,  then  thereafter  no adjustment  shall be required
               with respect to such dividend or distribution.

     (l)  Other Action  Affecting  Common Stock. If a state of facts shall occur
          which,  without being specifically  controlled by the other provisions
          of this Section 3, would not fairly protect the  conversion  rights of
          the Series A Preferred Stock in accordance  with the essential  intent
          and principles of such provisions,  then the Board of Directors of the
          Corporation  shall in good faith make an adjustment in the application
          of such  provisions,  in  accordance  with such  essential  intent and
          principles, so as to protect such conversion rights.

     (m)  Necessary  Corporate  Action.  Before  taking any action  which  would
          result in an adjustment in the Conversion Ratio, the Corporation shall
          obtain all such  authorizations  or  exemptions  thereof,  or consents
          thereto, as may be necessary from any public regulatory body or bodies
          having jurisdiction thereof.

     (n)  Taxes Upon  Conversion.  The  Corporation  shall pay all  documentary,
          stamp or other  transaction  taxes  attributable  to the  issuance  or
          delivery of shares of Common  Stock upon  conversion  of any shares of
          Series A Preferred Stock.

     (o)  Reservation  of  Common  Stock.  The  Corporation  shall at all  times
          reserve and keep available out of its  authorized but unissued  shares
          of Common Stock solely for the purpose of effecting the  conversion of
          shares of Series A Preferred Stock, the full number of whole shares of
          Common Stock then  deliverable  upon the  conversion  of all shares of
          Series A Preferred Stock at the time outstanding. All shares of Common


                                       9
<PAGE>

          Stock which shall be so issuable shall, when issued upon conversion of
          all or any  portion  of the  Series  A  Preferred  Stock,  be duly and
          validly  issued  and fully paid and  non-assessable  and free from all
          taxes,  liens and charges with respect to the issuance  thereof.  Upon
          conversion  of  Series A  Preferred  Stock,  the  shares  of  Series A
          Preferred  Stock so converted  shall have the status of authorized and
          unissued  Preferred  Stock,  and the  number  of  shares  of  Series A
          Preferred  Stock which the  Corporation  shall have authority to issue
          shall be decreased by any such conversion.

     (p)  Dividends  Constitute Corporate Debt. All dividends accrued and unpaid
          on Series A Preferred  Stock to and including the date of  conversion,
          whether or not declared by the Board of Directors,  shall constitute a
          debt of the  Corporation  payable  without  interest to the converting
          holders and shall be paid by the  Corporation on the Conversion  Date,
          in its option, either in cash or by the issuance of Dividend Shares as
          provided in Section 4 hereof.

4.   No Preemptive  Rights. No holder of Series A Preferred Stock shall have any
     preemptive or preferential  right of subscription to any shares of stock of
     the  Corporation,  or to options,  warrants or other  interests  therein or
     therefor, or to any obligations  convertible into stock of the Corporation,
     issued or sold,  or any right of  subscription  to any  thereof  other than
     such, if any, as the Board of Directors,  in its  discretion,  from time to
     time may  determine  and at such price or prices as the Board of  Directors
     from  time to time  may fix  pursuant  to the  authority  conferred  by the
     Corporation's Certificate of Incorporation.

5.   Certain  Restrictions.   So  long  as  any  Series  A  Preferred  Stock  is
     outstanding, the Corporation shall not, without the consent of holders of a
     majority  of the  outstanding  shares  of  Series A  Preferred  Stock,  (i)
     purchase,  redeem  or  otherwise  acquire  any  shares  of any class of the
     Corporation's  outstanding capital stock, (ii) issue any class or series of
     any class of capital  stock  which  ranks  prior to or pari passu with ----
     ----- the Series A  Preferred  Stock with  respect  to  dividend  rights or
     rights on liquidation,  winding-up or dissolution of the Corporation, (iii)
     amend,  alter or change the preferences or rights of any series or class of
     capital stock of the Corporation  (including the Series A Preferred  Stock)
     or  the  qualifications,   limitations  or  restrictions  thereof  if  such
     amendment,  alteration or change  adversely  affects the Series A Preferred
     Stock,  (iv) increase the authorized number of shares of Series A Preferred
     Stock, (v) take any action which results in the  liquidation,  acquisition,
     merger or sale of the  Company or all or  substantially  all of its assets,
     (vi) take any action which results in a change in the principal business of
     the Company,  or (vii) take any action which  results in the  repurchase of
     equity  securities,  other than the  repurchase of equity  securities  from
     Company employees.

                                       10
<PAGE>

6.   Definitions.

     (a)  "Additional  Shares of Common  Stock"  shall mean all shares of Common
          Stock issued by the Corporation after November 10, 1997, except Common
          Stock  which may be issued  pursuant  to:  (i) the  conversion  of the
          Series A Preferred Stock;  (ii) the exercise by the holders thereof of
          the  Corporation's  common stock purchase  warrants (the  "Warrants");
          (iii) the exercise by the holders  thereof of any options which may be
          granted  pursuant to the  Corporation's  Stock Option  Plan;  (iv) the
          exercise by the holders thereof of any currently  issued options;  and
          (v)  the  exercise  by  employees  of  the  Corporation  or any of its
          subsidiaries  of options  granted  pursuant  to any stock  option plan
          which may hereafter be adopted by the  Corporation  where the exercise
          price of such  options  is not less  than the fair  market  value of a
          share of Common Stock on the date of grant thereof.

     (b)  "Change  in  Control"  shall  mean a merger  or  consolidation  of the
          Corporation  with  any  other  corporation,  other  than a  merger  or
          consolidation  which  would  result in the  voting  securities  of the
          Corporation   outstanding  immediately  prior  thereto  continuing  to
          represent (either by remaining  outstanding or by being converted into
          voting  securities  of the  surviving  entity) at least fifty  percent
          (50%) of the  total of the  voting  power  represented  by the  voting
          securities of the  Corporation  or such surviving  entity  outstanding
          immediately  after such merger or consolidation or, except as provided
          under Section 2 hereof,  the closing of a sale or  disposition  by the
          Corporation of all or substantially  all of the  Corporation's  assets
          (other than to a subsidiary or subsidiaries of the Corporation).

     (c)  "Common   Stock"  shall  mean  the  shares  of  common  stock  of  the
          Corporation,  par value $.01 per share,  and any stock into which such
          Common Stock may hereinafter be changed.

     (d)  "Conversion Date" shall have the meaning such term is given in Section
          3(b) hereof.

     (e)  "Conversion  Notice"  shall  have the  meaning  such  term is given in
          Section 3(b) hereof.

     (f)  "Conversion  Ratio"  shall  have  the  meaning  such  term is given in
          Section 3(d) hereof.

     (g)  "Conversion  Shares"  shall  have the  meaning  such  term is given in
          Section 3(a) hereof.

     (h)  "Convertible Securities" shall mean evidences of indebtedness,  shares
          of stock or other securities which are convertible into or exercisable
          or   exchangeable   for,   with  or  without   payment  of  additional
          consideration  in cash or property,  for  Additional  Shares of Common
          Stock,  either  immediately or upon the arrival of a specified date or
          the happening of a specified event.

     (i)  "Current  Market  Price" per share of Common  Stock at any date herein
          specified  shall  mean the  average of the daily  market  prices for 5
          consecutive  Trading Days ending on the last trading day prior to such
          date,  except that for purposes of Section  3(c) hereof,  the "Current
          Market  Price" per share of Common Stock shall mean the market  prices
          on the Trading Day therein  specified.  The market price for each such


                                       11
<PAGE>

          Trading  Day shall be (i) if the Common  Stock is quoted on the Nasdaq
          National  Market or Nasdaq Small Cap Market,  the reported  last sales
          price, or (ii) if the Common Stock is listed or admitted to trading on
          a national securities exchange, the last reported sales prices regular
          way, or (iii) if the Common  Stock is quoted on the NASD OTC  Bulletin
          Board, the average of the closing bid and asked prices regular way, or
          (iv) if the Common Stock is not so quoted, as reasonably determined by
          the Board of Directors of the Corporation.

     (j)  "Liquidation  Preference" shall have the meaning such term is given in
          Section 2 hereof.

     (k)  "Person" shall mean any individual, corporation, association, company,
          business  trust,  partnership,  joint  venture,  joint-stock  company,
          trust, unincorporated organization or association or government or any
          agency or political subdivision thereof.

     (l)  "Securities Act" shall mean the Securities Act of 1933, as amended.

     (m)  "Trading  Day" shall mean any day on which  trading takes place (a) in
          the  over-the-counter-market  and prices  reflecting  such trading are
          published by the National  Association of Securities Dealers Automated
          Quotation System or (b) if the Common Stock is then listed or admitted
          to  trading  on a  national  securities  exchange,  on  the  principal
          national  securities exchange on which the Common Stock is then listed
          or admitted to trading.

     IN WITNESS  WHEREOF,  the undersigned has executed this Certificate this __
day of ___________, 1997. 

DERMA SCIENCES, INC.



By:____________________________
     Edward J. Quilty
     Chairman

ATTEST:

By: ___________________________
     _______________, Secretary

                                       12




                                WARRANT AGREEMENT


                  WARRANT  AGREEMENT dated as of November __, 1997 between Derma
Sciences,  Inc.,  a  Pennsylvania  corporation,  and  StockTrans,  Inc. a ______
corporation (hereinafter called the "Warrant Agent").

                  Derma  Sciences,   Inc.  (hereinafter  called  the  "Company")
proposes  to issue  common  stock  purchase  warrants  (hereinafter  called  the
"Warrants").  Each Warrant  entitles the holder thereof to purchase one share of
Common Stock, par value $.01 per share (the "Common Stock"), at a purchase price
of $0.90 per whole share. The Warrant Agent, at the request of the Company,  has
agreed to act as the  agent of the  Company  in  connection  with the  issuance,
registration,  transfer,  exchange, and exercise of Warrants. Each Warrant shall
be  exchangeable  at the  holder's  request  pursuant  to the terms of Section 6
hereof.

                  NOW,  THEREFORE,  in  consideration  of the mutual  agreements
herein set forth:

     SECTION 1.  Appointment of Warrant Agent.  The Company hereby  appoints the
Warrant  Agent  to  act  as  agent  for  the  Company  in  accordance  with  the
instructions  hereinafter  set forth in this  Agreement,  and the Warrant  Agent
hereby accepts such appointment.  The Company may from time to time appoint such
Co-Warrant  Agents as it may deem  necessary  or  desirable.  The Company  shall
promptly  notify the Warrant Agent from time to time in writing of the number of
Warrants to be issued and furnish written instructions in connection therewith.

     SECTION 2. Form of Warrant Certificates.  The Warrant Certificates (and the
forms of  election  to purchase  shares and of  assignment  to be printed on the
reverse  thereof)  shall be  substantially  of the tenor and purport  recited in
Exhibit  A  hereto  and may  have  such  letters,  numbers  or  other  marks  of
identification  or  designation  and such  legends,  summaries  or  endorsements
printed,  lithographed or engraved  thereon as the Company may deem  appropriate
and as are not inconsistent with the provisions of this Warrant Agreement, or as
may be  required  to  comply  with any law or with any rule or  regulation  made
pursuant  thereto or with any rule or regulation of any stock  exchange on which
the  Warrants  may from time to time be  listed,  or to  conform  to usage.  The
Warrant  Certificates  shall be dated as of the date of issuance  thereof by the
Warrant Agent,  either upon initial  issuance or upon transfer or exchange,  and
initially  shall  entitle  the holders  thereof to purchase  one share of Common
Stock,  but the number of such shares and the purchase price per share of Common
Stock shall be subject to adjustments as provided herein.

     SECTION 3.  Countersignature  and  Registration.  The Warrant  Certificates
shall be  executed on behalf of the  Company by the  Chairman  of the Board,  by
facsimile signature,  and shall be attested by the President or the Secretary of
the Company by facsimile  signature.  The Warrant Certificates shall be manually
countersigned by the Warrant Agent and shall not be valid for any purpose unless
so  countersigned.  In case any of the  Company who shall have signed any of the
Warrant   Certificates   shall   cease  to  be  such  of  the   Company   before
countersignature  by the Warrant Agent and issuance and delivery by the Company,
such Warrant  Certificates,  nevertheless,  may be  countersigned by the Warrant


                                       
<PAGE>

Agent,  issued and delivered with the same force and effect as though the person
who signed such  Warrant  Certificates  had not ceased to be such officer of the
Company;  and any Warrant Certificates may be signed on behalf of the Company by
any  person  who,  at  the  actual  date  of  the   execution  of  such  Warrant
Certificates,  shall be a proper  officer of the  Company  to sign such  Warrant
Certificates,  although at the date of the  execution of this Warrant  Agreement
any such person was not such an officer.

     The Warrant  Agent will keep or cause to be kept,  at one of its offices in
the City of Ardmore,  State of Pennsylvania  books for registration and transfer
of the Warrant  Certificates  issued hereunder.  Such books shall show the names
and addresses of the respective holders of the Warrant Certificates,  the number
of Warrants evidenced on its face by each of the Warrant  Certificates,  and the
date of each of the Warrant Certificates.

     The Warrant  Agent shall  countersign a Warrant  Certificate  only (a) upon
initial  issuance of the Warrants in accordance with the written order signed by
the Chairman of the Board and Chief Executive Officer, the President or any Vice
President  or (b)  upon  exchange,  transfer  or  substitution  for  one or more
previously countersigned Warrant Certificates as hereinafter provided.

     SECTION 4. Transfer and Exchange.  Subject to Section 6 hereof, the Warrant
Agent shall, from time to time, register the transfer of any outstanding Warrant
Certificate  upon the  books to be  maintained  by the  Warrant  Agent  for that
purpose, upon surrender thereof for transfer properly endorsed or accompanied by
appropriate  instruments of transfer and written instructions for transfer. Upon
any such registration of transfer,  a new Warrant Certificate shall be issued to
the transferee and the surrendered  Warrant Certificate shall be canceled by the
Warrant  Agent.  Any Warrant  Certificate  may be exchanged at the option of the
holder  thereof,  upon surrender at the office of the Warrant Agent specified in
Section  21  hereof,   for  another  Warrant   Certificate,   or  other  Warrant
Certificates of different denominations, representing in the aggregate the right
to  purchase a like  number of shares of Common  Stock.  No  fractional  Warrant
Certificates will be issued. The Company may require payment of a sum sufficient
to cover any tax or  governmental  charge that may be imposed in connection with
any transfer or exchange of Warrant Certificates.

     SECTION 5. Common Stock and Warrant Common Stock.  As  hereinafter  used in
this  Agreement,  Common  Stock  shall mean  stock of the  Company of any class,
whether now or hereafter  authorized,  which has the right to participate in the
distribution  of either  earnings or assets of the Company  without  limit as to
amount or percentage, and Warrant Common Stock shall mean only Common Stock, and
stock of any other class into which such presently  authorized  Common Stock may
hereafter be changed,  issuable  upon  exercise or exchange of the  Warrant.  In
case,  by reason of the  operation of Section 7, the Warrants  shall entitle the
registered  holders  thereof  to  purchase  any  other  shares of stock or other
securities or property of the Company or of any other corporation, any reference
in this  Agreement  to the  exercise  Warrants  shall be  deemed to refer to and
include  the  purchase  of such  other  shares of stock or other  securities  or
property upon such exercise.

     SECTION  6.  Warrant  Price;  Conversion  Date  of  Warrants;  Exchange  of
Warrants.  The  registered  holder of any Warrant  Certificate  may  exercise or


                                      -2-
<PAGE>

exchange  the Warrants  evidenced  thereby in whole or in part at any time on or
after the date hereof upon surrender of the Warrant Certificate with the form of
election to purchase or exchange on the reverse side thereof duly  executed,  to
the Warrant  Agent at the  principal  office of the Warrant Agent in the city of
Ardmore, State of Pennsylvania,  together with payment of the purchase price for
each one share of Common  Stock as to which the Warrants  are  exercised,  at or
prior to 3:30 p.m.  Eastern  Standard  Time on November 15, 2001 (the  "Exercise
Date").

     The purchase  price for each share of Common Stock pursuant to the exercise
of a Warrant  (the  "Warrant  Price")  shall be $0.90 during the period from the
date  hereof  until the  Exercise  Date,  in each case as  adjusted  pursuant to
Section 7 hereof,  and shall be payable in lawful money of the United  States of
America.

     The Warrants may be exchanged, in whole or in part, at the holder's option,
for that number of shares of Common Stock  obtained by dividing (x) the value of
the Warrant  (determined  by  subtracting  the aggregate  exercise  price of the
Warrant from the  aggregate  fair market value of the number of shares of Common
Stock  issuable upon  exercise of the Warrant),  by (y) the fair market value of
one share of Common Stock prior to the exchange.

     SECTION 7. Warrant Adjustments.  The Warrant Price and the number of shares
purchasable  upon  exercise  of a Warrant  shall be  subject  to  adjustment  as
follows:

     (a) Stock Dividends, Subdivisions,  Combinations and Reclassifications.  In
case the Company shall at any time after the date of this  Agreement (i) declare
a dividend on the Common Stock payable in shares of Common Stock, (ii) subdivide
the outstanding  Common Stock, (iii) combine the outstanding Common Stock into a
smaller  number of shares,  or (iv) issue any shares of its  capital  stock in a
reclassification  of the Common Stock  (including any such  reclassification  in
connection with a consolidation or merger in which the Company is the continuing
corporation),  the  Warrant  Price in effect at the time of the record  date for
such  dividend or of the  effective  date of such  subdivision,  combination  or
reclassification, and/or the number and kind of shares of capital stock issuable
upon exercise of the Warrants on such date shall be proportionately  adjusted so
that the holder of any  Warrant  exercised  after such time shall be entitled to
receive the aggregate  number and kind of shares of capital stock which, if such
Warrant had been exercised immediately prior to such date and at a time when the
Common Stock  transfer  books of the Company  were open,  such holder would have
owned  upon  such  exercise  and been  entitled  to  receive  by  virtue of such
dividend, subdivision, combination or reclassification. Such adjustment shall be
made successively whenever any event listed above shall occur.

     (b)  Subscriptions.  If at any time after the date hereof the Company shall
fix a record  date for the  issuance of rights or warrants to all holders of its
Common Stock,  entitling  them (for a period  expiring  within 45 days after the
record date  mentioned  below) to subscribe for or to purchase  shares of Common
Stock (or  securities  convertible  into  shares  of  Common  Stock) or having a
conversion  price per share of Common Stock (if a security is  convertible  into
Common Stock) at a price per share less than the Current  Market Price per share
of Common Stock on such record date (as  determined in the manner  prescribed in
Section 8 hereof) the Warrant  Price shall be decreased to an amount  determined


                                      -3-
<PAGE>

by  multiplying  such Warrant Price in effect  immediately  prior to such record
date by a fraction, the numerator of which is the sum of (x) the total number of
shares of Common Stock  outstanding  immediately  prior to such record date plus
the number of shares of Common Stock which the aggregate  offering  price of the
total  number  of  shares of Common  Stock so to be  offered  (or the  aggregate
initial  conversion price of the convertible  securities so to be offered) would
purchase at such Current Market Price and the  denominator of which shall be the
number of shares of Common Stock outstanding on such record date plus the number
of additional  shares of Common Stock to be offered for subscription or purchase
(or into  which  the  convertible  securities  so to be  offered  are  initially
convertible).  In case such  subscription  price may be paid in a  consideration
part or all of which  shall be in a form  other  than  cash,  the  value of such
consideration  shall be as  determined by the Board of Directors of the Company,
whose determination shall be conclusive, and described in a statement filed with
the Warrant Agent.  Such adjustment shall be made  successively  whenever such a
record date is fixed;  and in the event that such rights or warrants  are not so
issued,  the  Warrant  Price shall again be adjusted to be the price which would
then be in effect if such record date had not been fixed.

     (c)  Distributions.  If at any time after the date hereof the Company shall
fix a record date for the making of a distribution  to all holders of its Common
Stock of evidences of its indebtedness or assets  (excluding cash  distributions
made as a dividend  payable out of earnings or out of surplus legally  available
for dividends  under the laws of the  jurisdiction  of the Company) or rights to
subscribe  (excluding  those referred to in subsection (b) above),  then in each
case the Warrant Price in effect  immediately prior to such record date shall be
decreased  to an  amount  determined  by  multiplying  such  Warrant  Price by a
fraction, the numerator of which is the Current Market Price on such record date
less the then fair market value (as  determined by the Board of Directors of the
Company,  whose determination shall be conclusive,  and described in a statement
filed with the Warrant  Agent) of the assets or  evidences  of  indebtedness  so
distributed or of such  subscription  rights and the denominator of which is the
Current  Market  Price at such date.  The number of shares  purchasable  on such
record date shall be  increased to a number of shares equal to (i) the number of
shares  purchasable at the date of such  distribution  multiplied by the Warrant
Price in effect  immediately  prior to the adjustment  required by the preceding
sentence,  divided by (ii) the adjusted  Warrant Price computed  pursuant to the
preceding sentence.  Such adjustments shall be made successively whenever such a
record date is fixed;  and in the event that such  distribution  is not so made,
the Warrant  Price shall again be adjusted to the Warrant Price which would then
be in effect if such record date had not been fixed.

     (d)  Consolidation,  Merger or Sale of Assets. If, prior to the exercise of
any  Warrants,  the  Company  shall at any time  consolidate  with or merge into
another  corporation,  the holder of any Warrants will thereafter receive,  upon
the  exercise  thereof  in  accordance  with the  terms of this  Agreement,  the
securities  or  property  to which the  holder of the number of shares of Common
Stock then  deliverable  upon the exercise or conversion of such Warrants  would
have been entitled upon such consolidation or merger, and the Company shall take
such steps in connection with such  consolidation  or merger as may be necessary
to assure that the provisions  hereof shall thereafter be applicable,  as nearly
as  reasonably  may be, in relation  to any  securities  or property  thereafter
deliverable  upon the  exercise of the  Warrants.  The Company or the  successor
corporation,  as the case may be, shall execute and deliver to the Warrant Agent
a supplemental  agreement so providing.  A sale of all or substantially  all the
assets  of the  Company  for a  consideration  (apart  from  the  assumption  of
obligations)  consisting primarily of securities shall be deemed a consolidation


                                      -4-
<PAGE>

or merger for the foregoing  purposes.  The  provisions of this  subsection  (d)
shall similarly apply to successive  mergers or consolidations or sales or other
transfers.

     (e)  Calculations  to the Nearest  Cent and  One-Hundredth  of a Share.  No
adjustment in the Warrant Price shall be required unless such  adjustment  would
require an increase or decrease of at least 1% in such price; provided, however,
that any adjustments which by reason of this Section 7(e) are not required to be
made  shall  be  carried  forward  and  taken  into  account  in any  subsequent
adjustment.  All calculations  under this Section 7 shall be made to the nearest
cent  and  to  the  nearest  one-hundredth  of a  share  as  the  case  may  be.
Notwithstanding  the first  sentence  of this  subsection  (e),  any  adjustment
required by this Section 7 shall be made no later than the earlier of six months
from  the  date  of  the  transaction  which  mandates  such  adjustment  or the
expiration of the right to exercise any Warrant.

     (f) Notice of Warrant Adjustment.  Whenever the Warrant Price or the number
of shares  purchasable  upon exercise of a Warrant shall be adjusted as provided
in this Section 7, the Company  shall  forthwith  file with the Warrant  Agent a
certificate,  signed by a firm of  independent  public  accountants,  showing in
detail the facts  requiring such  adjustment and the Warrant Price and number of
shares so purchasable that will be effective after such adjustment.  The Company
shall also cause a notice  setting forth any  adjustments  to be sent by mailing
first class, postage prepaid, to each registered holder of a Warrant or Warrants
at its address appearing on the Warrant register and, at its option, may cause a
copy of such notice to be  published  once in an English  language  newspaper of
general  circulation  in the City of Ardmore,  Pennsylvania.  The Warrant  Agent
shall have no duty with respect to any certificate filed with, it except to keep
the same on file and available for inspection by registered  holders of Warrants
during  reasonable  business  hours.  The Warrant Agent shall not at any time be
under any duty or responsibility to any holder of a Warrant to determine whether
any facts exist which may require any adjustment of the Warrant  Price,  or with
respect to the nature of any  adjustment of the Warrant Price when made, or with
respect to the method employed in making such adjustment.

     (g) Other Notices.  In case the Company after the date hereof shall propose
to take any action of the type described in subsections (b), (c) and (d) of this
Section 7, the Company shall file with the Warrant Agent a  certificate,  signed
by the  Chairman,  President  or any Vice  President  of the  Company and by its
Treasurer or Assistant Treasurer or Secretary or Assistant Secretary specifying,
in the case of any action of the type  specified in subsection  (d), the date on
which  such  action  shall  take  place and shall also set forth such facts with
respect thereto as shall be reasonably  necessary to indicate the effect of such
action (to the extent such facts may be known on the date of such notice) on the
Warrant Price and the number, or kind, or class of shares or other securities or
property which shall be purchasable upon exercise of Warrants. Such notice shall
be given in the case of any action of the type specified in subsections  (b) and
(c), at least 10 days prior to the record date with  respect  thereto and in the
case of any  action of the type  specified  in  subsection  (d) at least 10 days
prior to the taking of such  proposed  action.  The  Company  shall also cause a
notice setting forth any adjustments to be sent by mailing first class,  postage
prepaid,  to  each  registered  holder  of  a  Warrant  Certificate  or  Warrant
Certificates  at its  address  appearing  on the  Warrant  register  and, at its
option,  may cause a copy of such  notice  to be  published  once in an  English
language newspaper of general circulation in the City of Princeton,  New Jersey.


                                      -5-
<PAGE>

Failure to give such notice or any defect  therein shall not affect the legality
or validity of such action.

     (h) No Change in Warrant Terms on  Adjustment.  Irrespective  of any of the
adjustments  in the  Warrant  Price or the  number of shares of  Warrant  Common
Stock,  Warrant  Certificates  theretofore or thereafter  issued may continue to
express the same prices and number of shares as are stated in a similar  Warrant
Certificate  issuable  initially,  or at some subsequent time,  pursuant to this
Agreement  and such number of Shares  specified  therein shall be deemed to have
been so adjusted.

     (i)  Treasury  Shares.  Shares  of  Common  Stock at any time  owned by the
Company shall not be deemed to be  outstanding  for purposes of any  computation
under this Section 7.

     (j) Optional Reduction in Warrant Price.  Anything in this Section 7 to the
contrary notwithstanding,  the Company shall be entitled to make such reductions
in the Warrant Price, in addition to those adjustments  required by this Section
7, as it in its sole  discretion  shall  determine to be necessary in order that
any  consolidation or subdivision of the Common Stock,  issuance wholly for cash
of any Common Stock at less than the Current Market Price,  issuance  wholly for
cash of Common Stock or securities  which by their terms are convertible into or
exchangeable for Common Stock,  stock dividend,  issuance of rights,  options or
warrants  referred to  hereinabove  in this Section 7,  hereinafter  made by the
Company to its common stockholders, shall not be taxable to them.

     The  Company  may,  at its  option,  at any  time  during  the  term of the
Warrants,   reduce  the  then  current  Exercise  Price  to  any  amount  deemed
appropriate by the Board of Directors of the Company, for any length of time.

     SECTION 8. Current Market Price.  For all purposes of this  Agreement,  the
Current Market Price per share of Common Stock on any date shall be deemed to be
the average of the daily closing prices for the thirty consecutive business days
commencing  before such date. The closing price for each day shall be (a) if the
Common  Stock  shall be listed or  admitted  to  trading  on the New York  Stock
Exchange,  the closing  price on the  NYSE-Consolidated  Tape (or any  successor
composite tape  recording  transactions  on the New York Stock  Exchange) or, if
such a composite  tape shall not be in use or shall not report  transactions  in
the Common  Stock,  or if the Common  Stock shall be listed on a stock  exchange
other than the New York Stock  Exchange,  the last reported  sales price regular
way on the  principal  national  securities  exchange on which the Common  Stock
shall be listed or admitted to trading  (which shall be the national  securities
exchange  on which the  greatest  number of shares of the Common  Stock has been
traded during such thirty  consecutive  business  days),  or, in either case, if
there is no transaction on any such day, the average of the bid and asked prices
regular  way on such  day,  or (b) if the  Common  Stock  shall not be listed or
admitted to trading on any national securities  exchange,  the closing price, if
reported,  or, if the closing price is not reported,  the average of the closing
bid and asked  prices,  as reported by the National  Association  of  Securities
Dealers  Automated  Quotation  (Nasdaq)  National  Market  or a  similar  source
selected  from time to time by the Company for the purpose.  If on any such date


                                      -6-
<PAGE>

the shares of Common Stock are not quoted by any such source,  the fair value of
such  shares  on such  date,  as  determined  by the Board of  Directors  of the
Company, shall be used.

     SECTION  9.  Exercise  of  Warrants.  Subject  to the  provisions  of  this
Agreement, each registered holder of Warrants shall have the right, which may be
exercised  as in such  Warrant  Certificates  expressed,  to  purchase  from the
Company  (and the  Company  shall issue and sell to such  registered  holders of
Warrants)  all or part of the number of fully paid and  nonassessable  shares of
Warrant  Common Stock  specified in such  Warrant  Certificates  (subject to the
adjustments as herein provided),  upon surrender to the Company at the office of
the Warrant Agent specified in Section 21 hereof,  of such Warrant  Certificates
with the exercise  form on the reverse  thereof  duly filled in and signed,  and
upon  payment to the Warrant  Agent to the account of the Company of the Warrant
Price for the number of shares of Warrant  Common Stock in respect of which such
Warrants are then exercised. The date of exercise of any Warrant shall be deemed
to be the date of its receipt by the Warrant Agent duly filled in and signed and
accompanied  by proper funds as  hereinafter  provided.  Payment of such Warrant
Price may be made in cash, or by certified or official bank check. No adjustment
shall be made for any cash  dividends on shares of Warrant Common Stock issuable
upon exercise of a Warrant. Upon such surrender of Warrants,  and payment of the
Warrant  Price as  aforesaid,  the Company shall issue and cause to be delivered
with all  reasonable  dispatch  to or upon the written  order of the  registered
holder of such Warrants and in such name or names as such registered  holder may
designate,  a  certificate  or  certificates  for the  number of full  shares of
Warrant  Common Stock so purchased  upon the exercise of such Warrants  together
with cash as  provided  in  Section  11 of this  Agreement,  in  respect  of any
fraction of a share of such stock issuable upon such surrender.

     Each  person in whose name any  certificate  for shares of Common  Stock is
issued upon the  exercise of Warrants  shall for all  purposes be deemed to have
become the holder of record of the Common Stock represented thereby on, and such
certificate  shall be  dated,  the  date  upon  which  the  Warrant  Certificate
evidencing  such Warrants was duly  surrendered and payment of the Warrant Price
(and any applicable  transfer taxes) was made;  provided,  however,  that if the
date of such  surrender  and  payment  is a date  upon  which the  Common  Stock
transfer  books of the Company are closed,  such person  shall be deemed to have
become the record holder of such shares on, and such certificate shall be dated,
the next succeeding business day on which the Common Stock transfer books of the
Company are open.

     SECTION  10.  Unexercised   Warrants.   To  the  extent  that  any  Warrant
Certificates remain outstanding at the expiration of the period during which the
Warrants are exercisable,  the unexercised Warrants represented thereby shall be
deemed null and void.

     SECTION 11. Elimination of Fractions.  The Company shall not be required to
issue fractional shares of stock upon any exercise of Warrants.  As to any final
fraction of a share which the same  registered  holder of one or more  Warrants,
the  rights  under  which are  exercised  in the same  transaction  or series of
related  transactions,  would  otherwise  be  entitled  to  purchase  upon  such
exercise,  the  Company  shall pay a cash  adjustment  in  respect of such final
fraction in an amount equal to the same fraction of the Current Market Price (as
determined  in the manner  prescribed  in Section 8 hereof) on the  business day
which next precedes the day of exercise.

                                      -7-
<PAGE>

     SECTION 12. Issue Taxes.  The Company will pay documentary  stamp taxes, if
any, attributable to the initial issuance of shares of Warrant Common Stock upon
the exercise of any Warrant; provided, however, that neither the Company nor the
Warrant  Agent shall be required to pay any tax or taxes which may be payable in
respect of any  transfer  involved in the issue or delivery of any  certificates
for shares of Warrant  Common Stock in a name other than that of the  registered
holder of Warrants, in respect of which such shares are initially issued.

     SECTION 13.  Reservation of Shares.  The Company shall at all times reserve
and keep available out of its authorized but unissued stock,  for the purpose of
effecting the issuance of stock upon exercise of Warrants, such number of shares
of its duly  authorized  Warrant  Common  Stock as  shall  from  time to time be
sufficient  to effect  the  issuance  of shares of  Warrant  Common  Stock  upon
exercise of all Warrants at the time outstanding.

     SECTION 14. Merger or Consolidation or Change of Name of Warrant Agent. Any
corporation  into which the Warrant  Agent may be merged or with which it may be
consolidated,  or any corporation  resulting from any merger or consolidation to
which the Warrant Agent shall be a party, or any  corporation  succeeding to the
corporate  trust  business of the Warrant  Agent,  shall be the successor to the
Warrant  Agent  hereunder  without the  execution  or filing of any paper or any
further act on the part of any of the  parties  hereto,  anything  herein to the
contrary notwithstanding.  In the case of Warrants which have been countersigned
by the Warrant  Agent,  but not delivered at the time any such  successor to the
Warrant  Agent  succeeds  to the  agency  created  by this  Agreement,  any such
successor  may adopt the  countersignature  of the  original  Warrant  Agent and
deliver  such  Warrants  so  countersigned;  and in case at that time any of the
Warrants shall not have been  countersigned,  any successor to the Warrant Agent
may  countersign  such Warrants  either in the name of the  predecessor  Warrant
Agent or in the name of the successor  Warrant Agent; and in all such cases such
Warrants  shall have the full force and effect  provided in the  Warrants and in
this Agreement.

     In case at any time the name of the  Warrant  Agent shall be changed and at
such time any of the Warrants shall have been  countersigned  but not delivered,
the  Warrant  Agent  may  adopt the  countersignature  under its prior  name and
deliver Warrant  Certificates so countersigned,  and in case at that time any of
the Warrant  Certificates shall not have been  countersigned,  the Warrant Agent
may  countersign  such Warrant  Certificates  either in its prior name or in its
changed  name;  and in all such cases such Warrant  Certificates  shall have the
full  force  and  effect  provided  in the  Warrant  Certificates  and  in  this
Agreement.

     SECTION 15.  Disposition  of Proceeds on  Exercise of  Warrants,  etc.  The
Warrant  Agent shall  account  promptly to the Company  with respect to Warrants
exercised and concurrently pay to the Company all moneys received by the Warrant
Agent for the  purchase of shares of Common  Stock  through the exercise of such
Warrants.

     The  Warrant  Agent  shall  keep  copies of this  Agreement  available  for
inspection  by holders of Warrants  during normal  business  hours at its office
specified in Section 21 hereof.

     SECTION 16. Supplements and Amendments. The parties hereto may from time to
time  supplement or amend this Agreement  without the approval of any holders of
Warrants  to cure any  ambiguity  or to  correct  or  supplement  any  provision


                                      -8-
<PAGE>

contained in this  Agreement  which may be defective  or  inconsistent  with any
other provision  contained herein, or to make such other provisions with respect
to any change or any supplemental agreement as the parties may deem necessary or
desirable and which shall not materially  adversely  affect the interests of the
registered holders of the Warrants.

     SECTION 17. Mutilated or Missing Warrant Certificates. If any Warrant shall
be  mutilated,  lost,  stolen or destroyed the Warrant Agent shall deliver a new
Warrant  Certificate of like tenor and denomination in exchange and substitution
therefor upon surrender and  cancellation of the mutilated  Warrant  Certificate
or, in the case of a lost, stolen or destroyed Warrant Certificate, upon receipt
of evidence satisfactory to the Company and the Warrant Agent of the loss, theft
or destruction of such Warrant  Certificate and, in either case, upon receipt of
such  indemnity  as the Company and the Warrant  Agent may  reasonably  require.
Applicants for substitute Warrant Certificates shall also comply with such other
reasonable  regulations  and pay such other  reasonable  charges as the  Warrant
Agent or the  Company may  prescribe.  Any such new  Warrant  Certificate  shall
constitute an original contractual obligation of the Company, whether or not the
allegedly lost, stolen,  mutilated or destroyed Warrant  Certificate shall be at
any time enforceable by anyone.

     SECTION 18. Duties of the Warrant Agent.  The Warrant Agent  undertakes the
duties and  obligations  imposed by this Warrant  Agreement  upon the  following
terms and  conditions,  by all of which the Company and the holders of Warrants,
by their acceptance thereof, shall be bound:

     The  Warrant  Agent  shall  not be  liable  for or by  reason of any of the
statements  of fact or recitals  contained  in this  Agreement or in the Warrant
Certificates (except its  countersignature  thereof and except such as describes
the Warrant Agent or action taken or to be taken by it) or be required to verify
the same,  but all such  statements and recitals are and shall be deemed to have
been  made by the  Company  only.  The  Warrant  Agent  shall  not be under  any
responsibility in respect of the validity of this Agreement or the execution and
delivery  hereof or in respect  of the  validity  or  execution  of any  Warrant
Certificate (except its countersignature  thereof);  nor shall it be responsible
for any breach by the Company of any  covenant or  condition  contained  in this
Agreement or in any Warrant Certificate to be complied with by the Company;  nor
shall it be responsible for the making of any adjustment in the Warrant Price or
the number of shares issuable upon the exercise of a Warrant  required under the
provisions of Section 7 or responsible  for the manner,  method or amount of any
such change or the ascertaining of the existence of facts that would require any
such  change;  nor  shall  it by  any  act  hereunder  be  deemed  to  make  any
representation  or warranty as to the authorization or reservation of any shares
to be issued  pursuant  to this  Agreement  or any  Warrant or as to whether any
shares will, when issued, be validly issued and fully paid and non-assessable.

     The  Warrant  Agent may execute  and  exercise  any of the rights or powers
hereby vested in it or perform any duty hereunder either itself or by or through
its  attorneys,  agents  or  employees,  and  the  Warrant  Agent  shall  not be
answerable or  accountable  for any act,  default,  neglect or misconduct of any
such  attorneys,  agents or employees  or for any loss to the Company  resulting


                                      -9-
<PAGE>

from such neglect or misconduct,  provided reasonable care had been exercised in
the selection and continued employment thereof.

     The Warrant Agent may consult at any time with legal  counsel  satisfactory
to it (who may be legal  counsel for the Company) and the advice of such counsel
shall provide complete  authorization  and protection to the Warrant Agent as to
any action  taken or omitted  by it in good  faith and in  accordance  with such
advice.

     The Warrant Agent shall incur no liability or responsibility to the Company
or to any holder of a Warrant  Certificate  for any action  taken in reliance on
any notice,  resolution,  waiver, consent, order,  certificate,  or other paper,
document or  instrument  believed  by it to be genuine and to have been  signed,
sent or presented by the proper party or parties.

     The Company agrees to pay to the Warrant Agent reasonable  compensation for
all  services  rendered by the Warrant  Agent in the  execution  of this Warrant
Agreement, to reimburse the Warrant Agent for all expenses (including reasonable
counsel fees), taxes and governmental  charges and other charges of any kind and
nature incurred by the Warrant Agent in the execution of this Warrant  Agreement
and to  indemnify  the Warrant  Agent and save it  harmless  against any and all
liabilities,  including  judgments,  costs  and  reasonable  counsel  fees,  for
anything  done or omitted by the Warrant  Agent in the execution of this Warrant
Agreement  except  as a  result  of  the  Warrant  Agent's  negligence,  willful
misconduct or bad faith.

     The Warrant Agent and any stockholder, director, officer or employee of the
Warrant Agent may buy, sell, or deal in any of the Warrants or other  securities
of the Company or become pecuniarily  interested in any transaction in which the
Company  may be  interested,  or  contract  with or lend money to the Company or
otherwise act as fully and freely as though it were not Warrant Agent under this
Warrant  Agreement.  Nothing herein shall preclude the Warrant Agent from acting
in any other capacity for the Company or for any other legal entity.

     The Warrant Agent shall act  hereunder  solely as agent for the Company and
in a  ministerial  capacity,  and its duties shall be  determined  solely by the
provisions  hereof.  The Warrant Agent shall not be liable for anything which it
may do or refrain from doing in connection  with this  Agreement  except for its
own negligence, willful misconduct or bad faith.


                                      -10-
<PAGE>

     SECTION 19.  Change of Warrant  Agent.  The Warrant Agent may resign and be
discharged  from its duties under this Agreement upon 30 days' notice in writing
mailed to the Company by registered or certified mail, and to the holders of the
Warrant  Certificates  by  first-class  mail. The Company may remove the Warrant
Agent or any successor Warrant Agent upon 30 days' notice in writing,  mailed to
the Warrant Agent or successor  Warrant  Agent,  as the case may be, and to each
transfer  agent of the Common Stock by registered or certified  mail, and to the
holders of the Warrant  Certificates  by first-class  mail. If the Warrant Agent
shall resign or be removed or shall otherwise  become  incapable of acting,  the
Company  shall  appoint a successor to the Warrant  Agent.  If the Company shall
fail to make such  appointment  within a period of 30 days after such removal or
after  it  has  been  notified  in of  such  resignation  by  the  resigning  or
incapacitated  Warrant  Agent or by the  holder  of a Warrant  Certificate  (who
shall, with such notice, submit such holder's Warrant Certificate for inspection
by the Company), then the registered holder of any Warrant Certificate may apply
to any court of  competent  jurisdiction  for the  appointment  of a new Warrant
Agent.

     SECTION 20. Identity of Transfer  Agent.  Forthwith upon the appointment of
any subsequent  Transfer Agent for shares of the Common Stock,  the Company will
file with the Warrant  Agent a statement  setting  forth the name and address of
such Transfer Agent.

     SECTION 21.  Notices.  Any notice pursuant to this Agreement to be given by
the  Warrant  Agent or by the  registered  holder of any  Warrant to the Company
shall  be  sufficiently  given if sent by  first-class  mail,  postage  prepaid,
addressed  (until  another  address is filed in writing by the Company  with the
Warrant Agent) as follows:

                                    Derma Sciences, Inc.
                                    214 Carnegie Center, Suite 100
                                    Princeton, New Jersey  08540
                                    Attention:  Edward J. Quilty

Any  notice  pursuant  to this  Agreement  to be given by the  Company or by the
registered  holder of any Warrant to the Warrant Agreement shall be sufficiently
given if sent by first-class  mail,  postage  prepaid,  addressed (until another
address is filed in writing by the Warrant Agent with the Company) as follows:

                                    StockTrans, Inc.
                                    7 East Lancaster Avenue
                                    Ardmore, Pennsylvania  19003

     SECTION 22. Successors.  All the covenants and provisions of this Agreement
by or for the benefit of the  Company or the Warrant  Agent shall bind and inure
to the benefit of their respective successors and assigns hereunder.

     SECTION 23. Governing Law. This Agreement and each Warrant issued hereunder
shall be deemed to be a contract  made  under the laws of New York,  and for all
purposes  shall be  construed  in  accordance  with the laws of New York without
regard to principles of conflict of laws.


                                      -11-
<PAGE>

     SECTION 24. Benefits of this Agreement.  Nothing in this Agreement shall be
construed  to give to any  person or  corporation  other than the  Company,  the
Warrant Agent and the registered  holders of the Warrant  Certificates any legal
or equitable  right,  remedy or claim under this  Agreement;  but this Agreement
shall be for the sole and  exclusive  benefit of the Company,  the Warrant Agent
and the registered holders of the Warrant Certificates.

     SECTION 25.  Counterparts.  This Agreement may be executed in any number of
counterparts and each of such  counterparts  shall for all purposes be deemed to
be an original,  and all such counterparts shall together constitute but one and
the same instrument.

     SECTION  26.  Registration  of Shares of Common  Stock.  The  Company  will
furnish to the Warrant Agent, upon request,  an opinion of counsel to the effect
that (i) a Registration  Statement under the Securities Act of 1933, as amended,
is then in effect with respect to the shares of Warrant  Common  Stock  issuable
upon  exercise of the  Warrants  and the  Prospectuses  hereinafter  referred to
comply as to form in all material respects with the requirements of said Act and
the rules and regulations of the Securities and Exchange Commission  thereunder;
or (ii) a Registration  Statement  under said Act with respect to said shares is
not  required.  In the event that said opinion  states that such a  Registration
Statement is in effect the Company will, from time to time,  furnish the Warrant
Agent with current  Prospectuses  meeting the  requirements  of said Act and all
rules and  regulations  thereunder in sufficient  quantity to permit the Warrant
Agent to deliver a Prospectus to each  transferee of a Warrant  Certificate  and
each holder of a Warrant  Certificate upon exercise or conversion  thereof.  The
Company  further agrees to pay all fees,  costs and expenses in connection  with
the preparation and delivery to the Warrant Agent of the foregoing  opinions and
Prospectuses.

     If any shares of Warrant  Common  Stock  issuable  upon the exercise of the
Warrants  or the  issuance  thereof  requires  registration  or  approval of any
governmental authority,  including,  without limitation, the filing of necessary
amendments, supplements or post-effective amendments to a Registration Statement
of the  Company  under the  Securities  Act of 1933,  or the taking of any other
action  under  the  laws  of the  United  States  of  America  or any  political
subdivision  hereof  or under  the laws of any  state of the  United  States  of
America before such shares may be validly and legally  issued,  then the Company
covenants that it will in good faith and as expeditiously  as possible  endeavor
to secure and keep effective such registration or approval or to take such other
action, as the case may be.


                                      -12-
<PAGE>




     IN WITNESS WHEREOF,  the parties hereto have caused this Warrant  Agreement
to be executed and delivered as of the day and year first above written.

                                                   DERMA SCIENCES, INC.



                                                   By:  ________________________
                                                           Edward J. Quilty
                                                           President


Attest:


_____________________________

Its:  _______________________

                                                   STOCKTRANS, INC.



                                                   By:  ________________________
                                                           Jonathan A. Miller
                                                           President
Attest:


_____________________________

Its:  _______________________








                                      -13-
<PAGE>






                                                                       EXHIBIT A

                     EXERCISABLE AT ANY TIME AT OR PRIOR TO
                    3:30 P.M. NEW YORK, EASTERN STANDARD TIME
                              ON NOVEMBER __, 2001

                               WARRANT CERTIFICATE
                              DERMA SCIENCES, INC.

                                                                     No. W-
- --------------------------------------------------------------------------------

- --------------------------------------------------------------------------------


                  This  certifies  that   _________________________________   or
registered  assigns is the registered holder of the number of Warrants set forth
above, and is entitled, upon surrender of this Warrant Certificate at the office
of StockTrans,  Inc., Warrant Agent (or any successor as such Warrant Agent), in
the city of  __________________,  _______________,  at any time on or after  the
date of the Warrant  Agreement (as defined) and at or prior to 3:30 p.m. Eastern
Standard  Time  November 15, 2001,  to purchase one share of Common  Stock,  par
value $.01, of Derma Sciences, Inc., a Pennsylvania corporation (the "Company"),
at the price of $0.90 per whole share.

                  The  applicable  per share  purchase price shown above and the
number of shares  issuable  upon  exercise of the Warrants  represented  by this
Warrant  Certificate  are subject to  adjustment  for the  occurrence of certain
events, including stock dividends and split-ups, combinations,  reorganizations,
reclassifications, consolidations, mergers or sales of properties and assets and
upon the  issuance of certain  rights or warrants to holders of Common  Stock or
the distribution to such holders of assets or indebtedness,  as set forth in the
Warrant Agreement  hereinafter referred to. A complete statement with respect to
such adjustments and to other terms and conditions pertaining to the Warrants is
contained in the Warrant  Agreement,  dated as of November 11, 1997, between the
Company and StockTrans, Inc., Warrant Agent (the "Warrant Agreement"), a copy of
which may be  examined  by the  registered  holder  hereof at the  office of the
Warrant Agent.

                  The Warrants  may be  exchanged,  in whole or in part,  at the
holder's option,  for that number of shares of Common Stock obtained by dividing
(x) the value of the Warrant (determined by subtracting,  the aggregate exercise
price of the  Warrant  from the  aggregate  fair  market  value of the number of
shares of Common Stock  issuable upon exercise of the Warrant),  by (y) the fair
market value of one share of Common Stock prior to the exchange.

                  To  exercise   the  Warrants   represented   by  this  Warrant
Certificate  the form of election to purchase on the reverse hereof must be duly
executed and the accompanying  instructions for the registration and delivery of
the stock must be filled in.

                  The  Warrants  represented  by this  Warrant  Certificate  are
transferable  (subject to the conditions set forth in the preceding  paragraphs)
at the office in the City of Ardmore,  Pennsylvania  of the Warrant Agent (or of
its  successor as Warrant  Agent) by registered  holder  thereof in person or by
attorney duly authorized in writing, upon surrender of this Warrant Certificate.

 
<PAGE>


Upon any such transfer,  a new Warrant  Certificate,  representing  the right to
purchase a like number of shares of the Company's  Common Stock,  will be issued
to the transferee in exchange for this Warrant Certificate.

                  This Warrant Certificate when surrendered at the office in the
City of Ardmore,  Pennsylvania  of the  Warrant  Agent (or of its  successor  as
Warrant  Agent) by the  registered  holder  hereof in person or by attorney duly
authorized  in writing may be  exchanged  for  another  Warrant  Certificate  or
Warrant Certificates, representing in the aggregate the right to purchase a like
number of shares of the Company's Common Stock.

                  If the Warrants  evidenced by this Warrant  Certificate remain
outstanding   at  the  expiration  of  the  period  during  which  Warrants  are
exercisable,  as set forth in the first  paragraph of this Warrant  Certificate,
such Warrants shall thereupon be deemed null and void.

                  No  fractional  shares of Common Stock will be issued upon the
exercise of any Warrant or Warrants  evidenced  hereby,  but in lieu thereof,  a
cash payment will be made, as provided in the Warrant Agreement.

                  No holder of this  Warrant  Certificate  shall be  entitled to
vote or  receive  dividends  or be deemed for any  purpose  the holder of Common
Stock  or of any  other  securities  of the  Company  which  may at any  time be
issuable on the exercise  hereof,  nor shall  anything  contained in the Warrant
Agreement or herein be construed to confer upon the holder hereof,  as such, any
of the  rights of a  stockholder  of the  Company  or any right to vote upon any
matter submitted to stockholders at any meeting thereof,  or to give or withhold
consent to any corporate  action  (whether upon any  recapitalization,  issue of
stock,  reclassification of stock, change of par value,  consolidation,  merger,
conveyance,  or otherwise) or, except as provided in the Warrant  Agreement,  to
receive notice of meetings,  or to receive  dividends or subscription  rights or
otherwise,  until the Warrant or Warrants evidenced by this Warrant  Certificate
shall have been exercised as provided in the Warrant Agreement.

                                                   DERMA SCIENCES, INC.


                                                   By:  ________________________
                                                           Edward J. Quilty
                                                           Chairman
Attest:


- ---------------------------
Secretary

                  This Warrant  Certificate is not valid until  countersigned by
the Warrant Agent.

                                                   Countersigned:

                                                   STOCKTRANS, INC.



                                                   ________________________
                                                        By:  Jonathan A. Miller
                                                             President


                                      -2-
<PAGE>




                                FORM OF EXERCISE

                 (Form of exercise to be executed by the Warrant
                         Holder at the time of exercise)


To StockTrans, Inc. or its successor as Warrant Agent:

                  The  undersigned,  holder of the within  Warrant  Certificate,
hereby (1) irrevocably  exercises the  undersigned's  right to purchase ________
shares of Common Stock, par value $0.01 per share, as Derma Sciences,  Inc. (the
"Company")  which the undersigned is entitled to purchase under the terms of the
within Warrant Certificate, or such other securities as the undersigned shall be
entitled to purchase  under the terms of the  Warrant  Agreement  referred to in
such Warrant Certificate by reason of the occurrence of certain events specified
therein,  and (2)  elects to make  payment  in full for the  number of shares of
Common  Stock so  purchased  by  payment  of $____  in cash or by  certified  or
official bank check.

                  Please issue the  certificate of shares of Common Stock in the
name of, and pay any cash for any fractional share to:


- --------------------------------------------------------------------------------
                               Print or type name

- --------------------------------------------------------------------------------
                   Social Security or other Identifying Number

- --------------------------------------------------------------------------------
                                 Street Address

- --------------------------------------------------------------------------------
                           State                                       Zip Code

If such  number  of  shares  shall not be all the  shares  purchasable  upon the
exercise of the Warrants  evidenced by this Warrant  Certificate,  a new Warrant
Certificate  for the balance of such  Warrants  remaining  unexercised  shall be
registered in the name of and delivered to:

- --------------------------------------------------------------------------------

Please insert social security
or other identifying number: ___________________________________________________


- --------------------------------------------------------------------------------
                         (Please print name and address)


Dated: ___________________           ________________________________________
                                                   Signature
                                 (Signature must conform in all respects to name
                                    of holder as specified on the face if the
                                              Warrant Certificate)


(Signature Medallion Guaranteed):  __________________       Date: ______________


(If the Common  Stock,  cash in lieu of fractional  shares,  or Warrants for any
unexercised  balance are to be issued or paid to a person  other than the person
in whose name the within Warrant is registered, or if otherwise requested by the
Company or the Warrant Agent, a signature Medallion guarantee is required.)



                                      -3-
<PAGE>



                                   ASSIGNMENT

                  (Form of assignment to be executed if Warrant
                       Holder desires to transfer Warrant)


                  FOR  VALUE   RECEIVED,   _____________________________________
hereby sells,  assigns,  and transfer unto  ______________________  this Warrant
Certificate  together with all right,  title or interest therein and does hereby
irrevocably  appoint  ______________________  attorney  to  transfer  the within
Warrant  Certificate  on the  books of the  Warrant  Agent  with  full  power of
substitution in the premises.

Dated: ___________        ____________________________________________
                                             Signature
                    (Signature must conform in all respects to name of holder as
                           specified on the face if the Warrant Certificate)


(Signature Medallion Guaranteed):  __________________       Date: ______________



                                      -4-






                           (FORM OF FACE OF DEBENTURE)

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE UNITED STATES  SECURITIES ACT OF
1933,  AS AMENDED  (THE  "SECURITIES  ACT"),  OR ANY STATE  SECURITIES  LAWS AND
NEITHER THIS SECURITY NOR ANY INTEREST OR  PARTICIPATION  HEREIN MAY BE OFFERED,
SOLD OR OTHERWISE  TRANSFERRED  WITHIN THE "UNITED STATES" OR TO "U.S.  PERSONS"
(AS DEFINED IN  REGULATION  S UNDER THE  SECURITIES  ACT) IN THE ABSENCE OF SUCH
REGISTRATION OR AN APPLICABLE EXEMPTION THEREFROM.  THE HOLDER OF THIS SECURITY,
BY ITS ACCEPTANCE HEREOF, REPRESENTS, ACKNOWLEDGES AND AGREES FOR THE BENEFIT OF
THE COMPANY THAT: (I) IT HAS ACQUIRED A "RESTRICTED" SECURITY WHICH HAS NOT BEEN
REGISTERED  UNDER THE SECURITIES ACT; (II) IT WILL NOT OFFER,  SELL OR OTHERWISE
TRANSFER  THIS  SECURITY,  PRIOR TO THE DATE WHICH IS ONE YEAR AFTER THE DATE OF
ORIGINAL  ISSUANCE HEREOF EXCEPT (A) TO DERMA SCIENCES,  INC., (B) PURSUANT TO A
REGISTRATION  STATEMENT  WHICH HAS BEEN DECLARED  EFFECTIVE UNDER THE SECURITIES
ACT, (C) OUTSIDE THE UNITED STATES IN A TRANSACTION  MEETING THE REQUIREMENTS OF
RULE 904  UNDER  THE  SECURITIES  ACT,  OR (D)  PURSUANT  TO  ANOTHER  AVAILABLE
EXEMPTION FROM THE REGISTRATION  REQUIREMENTS OF THE SECURITIES ACT AS CONFIRMED
IN AN OPINION OF COUNSEL  ACCEPTABLE IN FORM AND SUBSTANCE TO THE ISSUER OF THIS
SECURITY AND, IN EACH CASE, IN ACCORDANCE WITH THE APPLICABLE SECURITIES LAWS OF
ANY STATE OF THE UNITED STATES OR ANY OTHER APPLICABLE  JURISDICTION;  AND (III)
IT WILL, AND EACH SUBSEQUENT HOLDER IS REQUIRED TO, NOTIFY ANY PURCHASER FROM IT
OF THIS SECURITY OF THE RESALE  RESTRICTIONS SET FORTH IN (II) ABOVE. ANY OFFER,
SALE OR OTHER DISPOSITION PURSUANT TO THE FOREGOING CLAUSE (II)(D) IS SUBJECT TO
THE RIGHT OF THE ISSUER OF THIS  SECURITY TO REQUIRE THE  DELIVERY OF AN OPINION
OF COUNSEL,  CERTIFICATIONS OR OTHER INFORMATION  ACCEPTABLE TO THEM IN FORM AND
SUBSTANCE.



<PAGE>




                                      
                              DERMA SCIENCES, INC.
               (Incorporated in the Commonwealth of Pennsylvania)

                         CONVERTIBLE DEBENTURES DUE 1998

No. R-_______________                                        U.S. $____________


                  Derma  Sciences,  Inc., a corporation  duly  incorporated  and
existing under the laws of the Commonwealth of Pennsylvania (the "Company"), for
value received, hereby promises to pay to , or registered assigns, the principal
sum of United States Dollars on March 15, 1998 (the "Stated Maturity"),  subject
to extension as described herein.  The Stated Maturity shall be extended through
the date on which the  Company  obtains  authorization  for the  issuance of the
Series A Convertible Preferred Stock (such date, the "Authorization  Date"). The
Debentures  will  be  convertible  on  or  after  the  Authorization  Date.  The
Debentures  will accrue  interest  beginning  120 days from the date hereof at a
rate of 6% per annum,  payable quarterly,  with additional interest becoming due
each 90-day  period  following  such  initial  120-day  period  during which the
Company  has failed to obtain  authorization  for the  issuance  of the Series A
Convertible Preferred Stock.   Interest hereon  shall be calculated on the basis
of a 365/366 day year.

                  Reference  is hereby  made to the further  provisions  of this
Debenture  set forth under the Terms and  Conditions  of the  Debentures  on the
reverse hereof,  which further  provisions  shall for all purposes have the same
effect as if set forth at this place.

                  IN WITNESS  WHEREOF,  the Company has caused this Debenture to
be duly executed in its corporate name by the manual or facsimile signature of a
duly authorized  signatory,  as attested to by another duly authorized signatory
of the Company.

Dated:  ______________, 1997

                                             DERMA SCIENCES, INC.


                                             By:________________________________
                                                    Edward J. Quilty
                                                    Chairman


  ATTEST:


  By:__________________________________
        Name:
        Title:

                                      -ii-

<PAGE>


                                [Form of Reverse]
                     Terms and Conditions of the Debentures


1.       General.

         (a) This Debenture is one of a duly  authorized  issue of Debentures of
the Company designated as its Convertible Debentures due 1998 (herein called the
"Securities").

         (b) The Securities are issuable,  without coupons,  in denominations of
U.S. $20 and integral multiples thereof. The Securities,  and transfers thereof,
shall be in  registered  form as  provided in Section 6 hereof.  The  registered
holder of a Security shall (to the fullest extent  permitted by applicable  law)
be treated at all times,  by all  persons and for all  purposes as the  absolute
owner of such Security,  regardless of any notice of ownership, theft or loss or
of any writing thereon.

         (c) The Securities are direct  obligations of the Company.  Without the
approval  of the  holders  of the  Securities  or except as  otherwise  provided
herein,  the Company may not incur or issue any other indebtedness or securities
which ranks senior or pari passu to the Securities.

          (d) The Company has agreed, subject to shareholder  approval, to amend
its Certificate of  Incorporation  pursuant to that certain  Purchase  Agreement
dated November 10, 1997 by and between the Company and certain  Purchasers named
therein ("Purchase Agreement") to allow for the issuance of the shares of Series
A Preferred Stock,  $.01 par value,  set forth in the Purchase  Agreement within
120 days of the date hereof (the  "Authorization  Date"). The Company has agreed
to reserve for issuance the shares of the Company's common stock, $.01 par value
per share, underlying the shares of Series A Convertible Preferred Stock and the
warrants set forth in the Purchase  Agreement (the "Warrants")  (shares issuable
upon conversion of the Series A Preferred Stock and exercise of the Warrants are
collectively  referred to as the  "Underlying  Common  Stock").  On or after the
Authorization  Date,  the  Securities  shall  be  convertible  into  units  (the
"Units"),  each of which consists of one share of Series A Convertible Preferred
Stock and one Warrant.  Each Debenture shall be convertible  into such number of
Units as shall  result by dividing the  principal  amount of  Debentures  by the
purchase price per Unit. The Company has agreed to file and use its best efforts
to cause to become  effective not later than 90 days after the Closing Date (the
"Registration  Date") a  registration  statement on Form S-3 (the  "Registration
Statement")  covering  the resale of the shares of the  Underlying  Common Stock
issuable upon  conversion  of the shares of the Series A Preferred  Stock or the
exercise of the Warrants, as the case may be.

2.       Conversion.

         (a) Subject to and upon compliance with the provisions hereof, a holder
of  Securities  is  entitled,  at  its  option,  at any  time  on or  after  the
Authorization Date, to convert such Security into Units, as calculated above, by
surrender  of the  Security,  together  with  instruments  of  transfer  in form
satisfactory  to the Company,  duly executed by the registered  holder or by his
duly authorized  attorney and the conversion  notice hereon duly executed at the


<PAGE>

office of the Company or such other office as may be  designated  by it for such
purpose in Princeton, New Jersey or the City of New York.

         (b) No  payment  or  adjustment  shall be made upon any  conversion  on
account of any interest accrued on the Securities  surrendered for conversion or
on account of any  dividends on the  Underlying  Common  Stock.  No fractions of
shares or scrip representing  fractions of shares will be issued or delivered on
conversion,  but instead of any fractional interest the Company shall pay a cash
adjustment as provided herein.

3.       Events of Default.

         In the event that any of the  following  ("Events  of  Default")  shall
occur and be continuing:

         (a) the Company  shall fail to have  sufficient  shares of Common Stock
authorized  and  reserved  for issuance no later than 120 days after the Closing
Date to permit conversion of the Securities; or

         (b) the  Company  shall fail to  maintain  the  Registration  Statement
effective from the date of registration and for one year thereafter; or

         (c) the  Company  shall fail duly to perform or observe any other term,
covenant or agreement contained in any of the Securities for a period of 60 days
after the date on which written notice of such failure, requiring the Company to
remedy the same, shall first have been given to the Company by the holders of at
least  25%  in  aggregate  principal  amount  of  the  Securities  at  the  time
outstanding;  provided,  however, that in the event the Company shall within the
aforesaid  period  of 60 days  commence  legal  action  in a court of  competent
jurisdiction  seeking a  determination  that the  Company had not failed to duly
perform or observe the term or terms,  covenant or  covenants  or  agreement  or
agreements specified in the aforesaid notice, such failure shall not be an Event
of Default  unless the same  continues for a period of 10 days after the date of
any final  determination  to the  effect  that the  Company  had  failed to duly
perform or observe one or more of such terms, covenants or agreements; or

         (d) a court having jurisdiction in the premises shall enter a decree or
order for relief in respect of the Company in an involuntary  case or proceeding
under any applicable bankruptcy, insolvency, reorganization or other similar law
now or hereafter in effect,  or  appointing  a receiver,  liquidator,  assignee,
custodian, trustee, sequestrator (or similar official) of the Company or for any
substantial part of the property of it or ordering the winding-up or liquidation
of the  affairs of it and such  decree or order  shall  remain  unstayed  and in
effect for a period of 30 consecutive days; or

         (e) the Company shall commence a voluntary case or proceeding under any
applicable  bankruptcy,  insolvency,  reorganization or other similar law now or
hereafter in effect,  or shall consent to the entry of an order for relief in an
involuntary  case under any such law, or shall consent to the  appointment of or
taking  possession  by a receiver,  liquidator,  assignee,  trustee,  custodian,
sequestrator (or similar official) of the Company or for any substantial part of
its property, or shall make any general assignment for the benefit of creditors,


                                      -2-
<PAGE>

or shall admit in writing its  inability  to pay its debts as they become due or
shall take any corporate action in furtherance of any of the foregoing; or

         (f) an event of  default,  as defined in any  indenture  or  instrument
evidencing or under which the Company shall have  outstanding  at least $200,000
(or its  equivalent  in another  currency),  in  aggregate  principal  amount of
indebtedness for borrowed money,  shall have occurred and be continuing and such
default shall involve the failure to pay the principal of such  indebtedness (or
any part  thereof),  when due and payable after the expiration of any applicable
grace  period  with  respect  thereto,  or such  indebtedness  shall  have  been
accelerated  so that the same  shall be or become due and  payable  prior to the
date on which the same would otherwise have become due and payable,  and failure
to pay shall not have  been  cured by the  Company  within  30 days  after  such
failure or such  acceleration  shall not be rescinded or annulled within 60 days
after notice  thereof shall have first been given to the Company;  provided that
if such event of default under such indenture or instrument shall be remedied or
cured by the  Company or waived by the  holders of such  indebtedness,  then the
Event of Default  hereunder by reason  thereof shall be deemed  likewise to have
been thereupon remedied, cured or waived without further action upon the part of
any of the holders of Securities;

then the holder of this  Security  may,  at such  holder's  option,  declare the
principal of this Security and the interest accrued hereon to be due and payable
immediately  in cash by  written  notice to the  Company.  Upon  payment of such
amount of principal and interest in cash,  all of the Company's  obligations  in
respect  of  payment  of  principal  of and  interest  on  this  Security  shall
terminate.

         If an Event of Default,  as defined in this  Section 3, with respect to
the Securities,  or an event which would, with the passing of time or the giving
of notice,  or both be an Event of Default,  shall occur and be continuing,  the
Company  shall within two business  days of becoming  aware  thereof  notify the
holders in writing, of such Event of Default.

         The Company  shall  provide to the holders on each  anniversary  of the
date hereof,  a certificate to the effect that there is then existing no default
with respect to the Securities, as defined in this Section.

4.       Merger, Consolidation, Sale, Conveyance or Assumption.

         (a) The Company will not merge or  consolidate  with, or sell or convey
all or  substantially  all of its assets to, any other  corporation,  unless (i)
either  (A) the  Company  shall be the  surviving  corporation  in the case of a
merger or (B) the surviving, resulting or transferee corporation shall expressly
assume the due and punctual  payment of all the  Securities,  according to their
tenor,  and  the  due  and  punctual  performance  of all of the  covenants  and
obligations  of the Company  under the  Securities,  by  supplemental  agreement
reasonably  satisfactory to the holders of the  Securities,  (ii) the surviving,
resulting or transferee corporation, if not organized and validly existing under
the laws of the United States,  shall expressly agree to make payments under the
Securities  free of any  deduction  or  withholding  for or on account of taxes,
levies,  imposts  and  charges  whatsoever  imposed by or for the account of the
jurisdiction  where such successor  corporation is generally subject to taxation
(or any  political  subdivision  or taxing  authority  thereof or  therein) in a


                                      -3-
<PAGE>

manner equivalent to that set forth herein,  subject to the exceptions contained
in such  forms of the  Securities,  and  (iii)  the  Company  or such  successor
corporation,  as the case may be,  shall not,  immediately  after  such  merger,
consolidation,  sale or  conveyance,  be in  default in the  performance  of any
covenants or obligations of the Company under the Securities.

         (b) Upon any merger,  consolidation,  sale, conveyance or assumption as
provided in Section 4(a), the successor or assuming corporation shall succeed to
and be substituted for, and may exercise every right and power of and be subject
to all the  obligations  of, the  Company  under the  Securities,  with the same
effect  as if such  successor  or  assuming  corporation  had been  named as the
Company  therein and herein and the Company shall be released from its liability
as  obligor  under the  Securities;  provided  that any  successor  or  assuming
corporation  shall have the  obligation  to purchase  the  Securities  only as a
result of circumstances  which occur  subsequent to such merger,  consolidation,
sale,  conveyance or assumption  and as a result of which the Company would have
had such obligation if the Company had remained the obligor on the Securities.

                  In case of any such merger, consolidation, sale, conveyance or
assumption,  such  successor  or assuming  corporation  shall  succeed to and be
substituted  for the Company with the same effect,  subject to (in the case of a
merger to which the Company is a party) Section 4(b) of the Securities, as if it
had been named in the Securities as the Company;  the Company shall thereupon be
relieved  of  any  further  obligation  or  liability   hereunder  or  upon  the
Securities,  and the Company, as the predecessor corporation may thereupon or at
any time  thereafter be dissolved,  wound up or  liquidated.  Subject to all the
terms, conditions and limitations in the Securities prescribed, the successor or
assuming  corporation  shall deliver any Securities  which previously shall have
been signed and delivered by the officers of the Company.  All the Securities so
issued  shall in all  respects  have  the same  legal  rank and  benefit  as the
Securities theretofore or thereafter issued as though all of such Securities had
been issued at the date of the execution hereof.

                  In case of any  merger,  consolidation,  sale,  conveyance  or
assumption,  such changes in phraseology  and form (but not in substance) may be
made in the Securities thereafter to be issued as may be appropriate.

5.       Replacement, Transfer and Exchange of Securities.

         (a) In case any Security shall at any time become mutilated, destroyed,
stolen or lost and such Security or evidence of the loss,  theft or  destruction
thereof  (together  with the  indemnity  hereinafter  referred to and such other
documents or proof as may be required) shall be delivered to the Company,  a new
Security of like tenor and date with appropriate  interest coupons, if any, will
be issued by the Company in exchange for the Security so  mutilated,  or in lieu
of the Security so destroyed,  stolen or lost,  but, in the case of a destroyed,
stolen or lost  Security  only upon  receipt  of  evidence  satisfactory  to the
Company that such Security was destroyed, stolen or lost, and if required by the
Company,  upon  receipt  also of  indemnity  satisfactory  to the  Company.  All
expenses and  reasonable  charges  associated  with procuring such indemnity and
with the  preparation,  authentication  and delivery of a new Security  shall be
borne by the owner of the Security so mutilated, destroyed, stolen or lost.

         (b)  Securities  are  exchangeable  at the  office  of the  Company  in


                                      -4-
<PAGE>

Princeton,  New Jersey or as designated by the Company for such purpose,  for an
equal aggregate  principal  amount of Securities of authorized  denominations as
required by the holder  surrendering  the same.  In the event of conversion of a
Security  in part only,  a new  Security or  Securities  for the  unredeemed  or
unconverted portion hereof will be issued in the name of the holder thereof.

         (c) The costs and expenses of effecting any exchange or registration of
transfer  pursuant  to the  foregoing  provisions,  except for the  expenses  of
delivery by other than regular mail (if any) and except, if the Company shall so
require,  the payment of a sum sufficient to cover any tax or other governmental
charge or  insurance  charges that may be imposed in relation  thereto,  will be
borne by the Company.

         (d) For  purposes of the  provisions  of this  Security,  any  Security
authenticated   and  delivered   pursuant  hereto  shall,  as  of  any  date  of
determination, be deemed to be "outstanding," except for:

                  (i)      Securities  previously converted,  or canceled by the
         Company or delivered to the Company for cancellation;

                  (ii) Securities  which have become due and payable at maturity
         or  otherwise  and with  respect  to which  monies  or shares of Common
         Stock,  as  applicable,  sufficient  to pay the  principal  thereof and
         interest thereon shall have been made available to the Company; or

                  (iii) Securities in lieu of or in substitution for which other
         Securities have been authenticated and delivered pursuant hereto;

provided,  however,  that in  determining  whether the holders of the  requisite
principal  amount of outstanding  Securities are present at a meeting of holders
of  Securities  for  quorum   purposes  or  have  given  any  request,   demand,
authorization,  direction, notice, consent or waiver hereunder, Securities owned
by the Company or any subsidiary  thereof shall be disregarded and deemed not to
be outstanding.

6.       Modifications and Amendments.

         (a) Without the consent of any holders of Securities,  modifications of
or amendments to the Securities may be made for any of the following purposes:

                  (i)      to evidence the  succession of another corporation to
         the Company and  the assumption by  any such successor of the covenants
         of the Company in the Securities;

                  (ii) to add to the covenants of the Company for the benefit of
         the holders of  Securities,  or to surrender  any right or power herein
         conferred upon the Company;

                  (iii) to make provision with respect to the conversion  rights
         of holders of Securities pursuant to Section 2 hereof;

                  (iv) to cure any  ambiguity,  to  correct  or  supplement  any
         provision  herein which may be  inconsistent  with any other  provision
         herein; and


                                      -5-
<PAGE>


                  (v) to make any other  provisions  with  respect to matters or
         questions arising under this Security;

                  No such action  pursuant to this  paragraph  (a) may adversely
affect the interests of the holders of Securities.

         (b)  Modifications  and amendments to these Securities may be made, and
future  compliance  with  or  past  default  by  the  Company  under  any of the
provisions thereof may be waived,  with the written consent of the holders of at
least a majority in aggregate  principal  amount of the  Securities  at the time
outstanding,  provided,  that no such  modification,  amendment  or waiver  may,
without the consent of the holder of each such Security affected thereby:

                  (i)      waive a default in the payment of the principal of or
         interest on any Security;

                  (ii)  change  the  Stated  Maturity  (except  as  contemplated
         herein) of the  principal  of or any  installment  of interest  on, any
         Security,  or  reduce  the  principal  amount  thereof  or the  rate of
         interest thereon,  or change the coin or currency in which any Security
         or the interest  thereon is payable,  or adversely  affect the right to
         convert  any  Securities  as  provided  in  Section  2  or  modify  the
         provisions  of the  Securities  with  respect to  subordination  of the
         Securities in a manner adverse to the holders;

                  (iii) reduce the  requirements  of Section 6 hereof for quorum
         or  voting,  or  reduce  the  percentage  in  principal  amount  of the
         outstanding Securities the consent of whose holders is required for any
         amendment  or   modification   of  the  Terms  and  Conditions  of  the
         Securities;

                  (iv)  change the  obligation  of the  Company to  maintain  an
         office or agency in Princeton, New Jersey or the City of New York; or

                  (v) modify any of the  provisions  of this  Section  except to
         increase  any  such   percentage  or  to  provide  that  certain  other
         provisions of the  Securities  cannot be modified or waived without the
         consent of the holder of each outstanding Security affected thereby.


                                      -6-
<PAGE>

7.       Non-Business Days.

         In any case where the date of maturity of the  principal of or interest
on the  Securities or the date fixed for  redemption of any Security shall be at
any place of  payment a  Saturday,  Sunday,  a legal  holiday  or a day on which
banking  institutions  in  Princeton,  New  Jersey  or the  City of New York are
authorized  or  obligated by law or  executive  order to close,  then payment of
principal  or  interest  need not be made on such date at such  place but may be
made on the  next  succeeding  day at  such  place  of  payment  which  is not a
Saturday,  Sunday,  a legal  holiday or a day on which banking  institutions  in
Princeton, New Jersey or the City of New York are authorized or obligated by law
or  executive  order to close,  with the same force and effect as if made on the
date of maturity or the date fixed for redemption,  and no interest shall accrue
for the period after such date.

8.       Security Register.

         The Company shall cause to be kept at its  principal  office a register
(the "Security Register") in which, subject to such reasonable regulations as it
may prescribe,  the Company shall provide for the registration of Securities and
of transfers of Securities.

         As provided herein and subject to certain limitations therein set forth
and compliance by the holder with applicable state and federal  securities laws,
the  transfer  of  Securities  is  registrable  on the  Security  Register  upon
surrender of a Security for  registration of transfer at the office or agency of
the  Company,  duly  endorsed  by, or  accompanied  by a written  instrument  of
transfer  in form  satisfactory  to the  Company  duly  executed  by, the holder
thereof or his attorney duly  authorized  in writing,  and thereupon one or more
new Securities, of authorized denominations and for the same aggregate principal
amount, will be issued to the designated transferee or transferees.

9.       Notices.

         All notices to the holders of  Securities  will be mailed to registered
holders of Securities at their registered  addresses as the same shall appear in
the Security Register on the day fifteen days prior to such mailing.

10.      Governing Law.

         The  Securities  shall be governed by and construed in accordance  with
the laws of the State of New  York,  without  giving  effect  to  principles  of
conflicts of law.

11.      Countersignature and Registration.

         This  Security  shall not become  valid or  obligatory  for any purpose
until the certificate  representing  this Security shall have been duly executed
by the Company and such signature attested to by an authorized Officer thereof.



                                      -7-
<PAGE>

12. Warranty of the Company.

         The Company hereby certifies and warrants that all acts, conditions and
things  required to be done and performed and to have happened  precedent to the
creation and issuance of this Security,  and to constitute the same legal, valid
and binding  obligations  of the Company  enforceable  in accordance  with their
terms,  have  been  done and  performed  and  have  happened  in due and  strict
compliance with all applicable laws.

13.      Accounting Terms.

         All  accounting  terms not  otherwise  defined  herein  shall  have the
meanings  assigned to them in  accordance  with  generally  accepted  accounting
principles as applied in the United States.

14.      Descriptive Headings.

         The  descriptive  headings  appearing  herein  are for  convenience  of
reference only and shall not alter, limit or define the provisions hereof.



                                      -8-
<PAGE>



                                 TRANSFER NOTICE

         Only if a Security or Unit issued upon  conversion  of any  Security is
transferred (if no registration statement covering the securities comprising the
Units is effective):

FOR VALUE  RECEIVED,  the  undersigned  Holder  hereby  sell(s),  assign(s)  and
transfer(s) unto ________________________________________________ whose taxpayer
identification number is ________________ and whose address including postal/zip
code is_________________________________________________________________________
___________________________________________________________  the within Security
and all  rights  thereunder,  hereby  irrevocably  constituting  and  appointing
_________________ attorney-in-fact to transfer said Security on the books of the
Company with full power of substitution in the premises.

         In  connection  with the  transfer of this  Security,  the  undersigned
Holder certifies that:

         (Check one)

     [ ]  (a)   This  Security  is being  transferred  with the  consent  of the
          Company  to  a  sophisticated   institutional  investor  which  is  an
          "accredited  investor"  (within the  meaning of Rule 501(a)  under the
          Securities Act of 1933, as amended) in a transaction not involving any
          general solicitation or advertising.

     [ ]  (b)    This  Security  is  being  transferred  pursuant  to any  other
          exemption from, or in a transaction  not subject to, the  registration
          requirements  of the Securities Act of 1933, as amended,  as confirmed
          in an attached opinion of U.S. counsel.


Dated:_____________                         Name:______________________________

                                            By:________________________________

                                            Title:_____________________________

                                            NOTICE:  The signature of the Holder
                                            to this  assignment  must correspond
                                            with  the name as  written  upon the
                                            face  of the  within  instrument  in
                                            every      particular,       without
                                            enlargement     or    any     change
                                            whatsoever.

                                            SIGNATURE GUARANTEED


                                            -----------------------------------




                                      -9-
<PAGE>




TO BE COMPLETED BY A BROKER OR DEALER IF (b) ABOVE IS CHECKED:

         The  undersigned  represents  and  warrants  that (i) it is a broker or
dealer  registered  under Section 15 of the Securities  Exchange Act of 1934, as
amended;  (ii) each person which will become a beneficial owner of this Security
upon transfer is a sophisticated  institutional investor which is an "accredited
investor"  (within the meaning of Rule 501(a) under the  Securities Act of 1933,
as amended); (iii) no general solicitation or advertising was made or used by it
in connection  with the offer and sale of this Security to such  person(s);  and
(iv)  each  such  person  has been  notified  that  this  Security  has not been
registered  under the Securities Act of 1933, as amended,  and is subject to the
restrictions on transfer of the Security set forth herein.



Dated:______________                        _____________________________

                                            By: _________________________

         IF NONE OF THE  FOREGOING  BOXES IS CHECKED,  THE HOLDERS  SHALL NOT BE
OBLIGATED  TO  REGISTER  THE  TRANSFER  OF THIS  SECURITY  UNLESS  AND UNTIL THE
CONDITIONS TO ANY SUCH TRANSFER OF  REGISTRATION  SET FORTH HEREIN,  ON THE FACE
HEREOF SHALL HAVE BEEN SATISFIED.




                                      -10-
<PAGE>




                                CONVERSION NOTICE

         The undersigned  holder of this Security hereby  irrevocably  exercises
the option to convert this Security,  or portion hereof (which is U.S. $20 or an
integral multiple thereof) below designated,  into Units of Derma Sciences, Inc.
in  accordance  with the terms of this  Security,  and directs that such shares,
together  with a check in payment for any  fractional  share and any  Securities
representing  any unconverted  principal  amount hereof,  be delivered to and be
registered  (if a Security)  in the name of the  undersigned  unless a different
name has been indicated  below.  If shares or Securities are to be registered in
the name of a person other than the  undersigned,  the undersigned  will pay all
transfer taxes payable with respect thereto.


Dated:______________                        ____________________________
                                             Signature
                                                [MUST BE GUARANTEED]




<PAGE>


If Securities  are to be registered in the name of, or a check in payment of the
purchase  amount of any  fractional  share is to be to, a Person  other than the
holder, please print such person's name and address:

- ------------------------------

- ------------------------------

- ------------------------------


If only a portion of the Securities is to be converted please indicate:

1.       Principal Amount to be converted: U.S. $____________

2.  Kind,  amount  and  denomination  of  Securities  representing   unconverted
principal amount to be issued:

U.S. $_____________________

Denominations:  U.S. $_______
(U.S. $20 or an integral multiple thereof)

                                      -11-




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