VENTANA MEDICAL SYSTEMS INC
8-K/A, 1998-12-28
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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          SECURITIES AND EXCHANGE COMMISSION
                           
                Washington, D.C.  20549
                           
                      FORM 8-K/A
                           
                    Amendment No. 1
         (Amending Items 7(a), 7(b) and 7(c))
                           
                    CURRENT REPORT



   Pursuant to Section 13 or 15(d) of the Securities
                 Exchange Act of 1934

   Date of Report (Date of earliest event reported):
                   October 14, 1998



             VENTANA MEDICAL SYSTEMS, INC.
(Exact name of registrant as specified in its charter)


      Delaware            2-20931            94-2976937
  (State or other       (Commission        (IRS Employer
  jurisdiction of       File Number)       Identification
   incorporation)                               No.)


    3865 North Business Center Drive
          Tucson, Arizona                      85705
(Address of principal executive offices)     (Zip Code)

Registrant's telephone number, including area code: (520) 887-2155

<PAGE>

     This Amendment No. 1 to Form 8-K supplements the
Form 8-K filed on October 28, 1998 by the Company.  At
the time of the filing of the Form 8-K, it was
impracticable for the Company to provide the financial
statements of the business acquired and the pro forma
financial information required by Items 7(a) and 7(b).

Item 7.  Financial Statements and Exhibits

          (a)  Audited Financial Statements as of April
          30, 1998 and 1997 of Biotechnology Tools,
          Inc.

               Unaudited Interim Financial Statements
          as of and for the five months ended September
          30, 1998 of Biotechnology Tools, Inc.

          (b)  Pro forma Financial Information

               Included in this Report is the following
          pro forma financial information:

                    1.   Unaudited Pro Forma Condensed
               Consolidated Balance Sheet as of
               September 30, 1998.

                    2.   Unaudited Pro Forma Condensed
               Consolidated Statement of Operations for
               the year ended December 31, 1997.

                    3.   Unaudited Pro Forma Condensed
               Consolidated Statement of Operations for
               the nine months ended September 30,
               1998.

                    4.   Notes to Unaudited Pro Forma
               Condensed Consolidated Financial
               Statements.

               (c)  Exhibits

                    23.1 Consent of Kempisty and
               Company.

<PAGE>

Item 7(a)

          Board of Directors and Stockholders
               Biotechnology Tools, Inc.

We have audited the accompanying balance sheets of
Biotechnology Tools, Inc. (Formerly Research and
Manufacturing Company Inc.) as of April 30, 1998 and
1997, and the related statements of operations,
shareholders' equity and cash flows for each of the two
years in the period ended April 30, 1998.  These
financial statements are the responsibility of the
Company's management.  Our responsibility is to express
an opinion on these financial statements based on our
audits.   We conducted the audits in accordance with
generally accepted auditing standards.  Those standards
require that we plan and perform the audit to obtain
reasonable assurance about whether the financial
statements are free of material misstatement.  An audit
includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial
statements.  An audit also includes assessing the
accounting principles used and significant estimates
made by management, as well as evaluating the overall
financial statement presentation.  We believe that our
audits provide a reasonable basis for our opinion.  In
our opinion, the financial statements referred to above
present fairly, in all material respects, the financial
position of Biotechnology Tools, Inc. as of April 30,
1998 and 1997, and the results of its operations,
shareholders' equity and cash flows for each of the two
years in the period ended April 30, 1998 in conformity
with generally accepted accounting principles.


Kempisty & Company
Certified Public Accountants PC
New York, New York
August 20, 1998

<PAGE>

                BIOTECHNOLOGY TOOLS, INC.

  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)


                  FINANCIAL STATEMENTS

               YEAR ENDED  APRIL 30, 1996


CONTENTS

Report of Independent Auditors                                    1

Financial Statements

Balance Sheets                                                    2

Statements of Operations                                          4

Statements of Stockholders' Equity                                5

Statements of Cash Flows                                          6

Notes to Financial Statements                                     7-12

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
                           
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                           
                    BALANCE SHEETS

   
                                                   April 30,
                                                1998       1997
     ASSETS
 Current Assets
   Cash                                       $ 1,782     $ 11,182
   Accounts receivable (net of 
     allowance for doubtful accounts 
     of $55,000 in 1997 and 1998)             826,566      462,528
   Due from factor (Note 3)                    97,635       15,965
   Inventories (Note 5)                     1,374,519    1,607,399
           Total Current Assets             2,300,502    2,097,074

 Property, plant and equipment
   Furniture and fixtures                     118,790      118,120
   Machinery and equipment                    348,640      343,640
                                              467,430      461,760

 Less accumulated depreciation 
   and amortization                         (460,731)    (449,099)
                                                6,699       12,661

 Inventories - noncurrent (Note 5)            144,286      168,733

 Other Assets
   Deposits receivable                         32,172       13,110
   Employee advances                            2,066            -
           Total Other Assets                  34,238       13,110
 TOTAL ASSETS                              $2,485,725   $2,291,578

           See notes to financial statements

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
                           
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                           
                    BALANCE SHEETS
                                                       


                                                    April 30,
                                                 1998       1997
     LIABILITIES & STOCKHOLDERS' EQUITY
 Current liabilities:
  Bank overdraft                               $66,590     $      -
  Accounts payable                             852,998      938,012
  Accrued expenses                             300,902      297,829
  Debentures payable (Note 6)                   63,705      229,705
  Taxes payable                                 25,860       16,500
  Deferred revenue                             142,131      150,731
  Due to affiliates                            113,920      111,620
  Due to officers (Note 4)                     440,578      446,453
  Advance from Sherwood Medical                355,580      355,580
          Total Current Liabilities          2,362,264    2,546,430
                                                                        
 Commitments (Note 9)                                                    
                                                                       
 Stockholders' Equity                                                     
  Common stock, $.001 par value,                                            
    20,000,000 shares authorized,                                           
    3,789,100 and 3,789,100 shares                                           
    issued and outstanding (Note 9)              3,789        3,789
  Subscriptions receivable                     (2,345)      (2,345)
  Preferred stock $.01 par value, 
    1,000,000 shares authorized,
    no shares issued or outstanding                  -            -
  Additional paid-in capital                 1,020,699    1,020,699
  Retained earnings (deficit)                (898,682)  (1,276,995)
          Total Stockholders' Equity           123,461    (254,852)
 TOTAL LIABILITIES & STOCKHOLDERS' EQUITY   $2,485,725   $2,291,578


           See notes fo financial statements

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
                           
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                           
               STATEMENTS OF OPERATIONS



                                             April 30,
                                          1998       1997

 Net sales                            $5,384,611   $4,909,478
 Cost of goods sold                    2,941,369    2,745,855
 Gross margin                          2,443,242    2,163,623

 Operating expenses:
 Selling, general and administrative   1,990,115    3,151,176
 Interest                                 98,700      208,847
 Total operating expenses              2,088,815    3,360,023
 Income (loss) from operations           354,427  (1,196,400)

 Other income (expense)                        -            -
 Gain on sale of building                      -      628,559
 Interest income                             162           85
 Gain on extinguishment of debt           10,724      425,804
 Gain on sale of equipment                13,000            -
 Income (loss) before income taxes       378,313    (141,952)

 Income taxes (Note 8)                         -            -
 Income (loss) from continuing 
   operations                            378,313    (141,952)

 Net income (loss)                       378,313    (141,952)

 Net income (loss) per common share       $ 0.10     $ (0.04)

 Average number of common shares       3,789,100    3,904,742

 Dividends per common share           $        -   $        -

          See notes to financial statements.

<PAGE>
                           
              BIOTECHNOLOGY TOOLS, INC.
 (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
          STATEMENTS OF STOCKHOLDERS' EQUITY

<TABLE>
<CAPTION>
                             Common Stock      Additional                     Retained
                          ($.001) Par Value     Paid-In      Subscription    Earnings
                          Shares      Amount    Capital       Receivable      (Deficit)      Total
<S>                         <C>         <C>      <C>             <C>             <C>

Balance April 30, 1996  4,101,762     $4,102   $1,099,492       $(2,500)    $(1,213,994)  $(112,900)

Cancellation of stock
issued for services     (157,900)      (158)     (78,793)              -          78,951           0

Cancellation of stock
issued for subscription 
receivable              (154,762)      (155)            -            155               -           0

Net loss                        -          -            -              -       (141,952)   (141,952)

Balance April 30, 1997  3,789,100      3,789    1,020,699        (2,345)     (1,276,995)   (254,852)

Net income                      -          -            -              -         378,313     378,313

Balance April 30, 1998  3,789,100     $3,789   $1,020,699       $(2,345)      $(898,682)    $123,461

</TABLE>

          See notes to financial statements.

<PAGE>

                 BIOTECHNOLOGY TOOLS, INC.
                                                       
      (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                                                       
                 STATEMENTS OF CASH FLOWS
                                                       


April 30,
                                                 1998       1997
  Cash Flows From Operating Activities:
 Net income (loss)                             $378,313     $(141,952)
 Adjustments to reconcile net loss 
   to net cash used in operating 
   activities:
 Depreciation and amortization                   11,632       58,977
 Gain on cancellation of debt                  (10,724)     (425,804)
 Gain on sale of fixed assets                         -     (628,558)
 Changes in operating assets and liabilities:
 Accounts receivable - trade                  (364,038)      (81,729)
 Income tax receivable                                -        57,757
 Due from factor                               (81,670)       151,041
 Due from affiliates                              2,300       130,242
 Inventories                                    257,327       212,398
 Other assets                                  (21,128)       142,880
 Accounts payable and accrued expenses         (15,351)     (890,534)
 Income taxes payable                             9,360        16,500
 Due to officers                                 (5,875)      437,693
 Other liabilities                               (8,600)     (13,116)
  Cash provided by operating activities          151,546    (974,205)

  Cash Flow From Investing Activities:
 Sale of property, plant and equipment           (5,670)    1,750,134
  Cash used in investing activities              (5,670)    1,750,134

  Cash Flows From Financing Activities:
 Principal payment of long term debt           (155,276)    (810,361)
  Cash used in financing activities            (155,276)    (810,361)

 Net decrease in cash                            (9,400)     (34,432)
 Cash, beginning of the year                      11,182       45,614
 Cash, end of the year                           $  1,78     $ 11,182

 Supplementary cash flow information:
   Taxes paid                                    $     -     $      -
   Interest paid                                 $90,000     $ 82,000

          See notes to financial statements.

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
                           
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                           
             NOTES TO FINANCIAL STATEMENTS
                                                       
                    APRIL 30, 1998

1. - DESCRIPTION OF BUSINESS

   Biotechnology Tools, Inc. (BTI or the Company) a
   Delaware Corporation (formerly Research and
   Manufacturing Company, Inc.) manufactures and
   markets a wide range of microtome products,
   cryogenic hardware and peripheral equipment,
   primarily  for research and educational insitutions
   in the United States, Europe and the Far East.

2. - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

   a. Revenue Recognition

     Sales are recorded when goods are shipped and
     profit is recognized at that time.  Revenue from
     service contracts is deferred and taken into
     income on a straight-line basis over the period of
     the contract.


   b. Inventories

     Inventories are stated at the lower of cost or
     market.  Cost is computed on the first-in, first-
     out basis.  A certain portion of the Company's
     inventories consists of parts maintained solely
     for the repair and/or replacement of finished
     products previously sold. However, management
     cannot predict the anticipated future demand or
     usage for such inventories.  These parts are
     classified as inventory - noncurrent.

   c. Property, Plant and Equipment

     Property, plant and equipment are stated at cost.
     Depreciation is provided using the straight-line
     method over the estimated useful lives of the
     related assets as follows:

     Leasehold improvements        life of lease
     Furniture and fixtures              7 years
     Machinery and equipment             5 years

     Expenditures for major renewals and betterments
     are capitalized while repairs and maintenance are
     expensed.

   d. Research and Development Costs

     For financial reporting purposes, all costs of
     research and development activities are expensed
     as incurred.

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
                           
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                           
             NOTES TO FINANCIAL STATEMENTS
                                                       
                    APRIL 30, 1998

   e.  Income Taxes
   
      The Company accounts for income taxes using the
      liability method.  Deferred tax assets and
      liabilities are determined based on differences
      between financial reporting and tax bases of
      assets and liabilities and are measured using
      enacted tax rates and laws expected to be in
      effect when the differences are expected to
      reverse.  Valuation allowances are established
      when necessary to reduce the carrying amount of
      deferred tax assets to their net realizable
      value.
                                                       
   f.   Use of Estimates
                                                       
      The preparation of financial statements in
      accordance with generally accepted accounting
      principles requires management to make estimates
      and assumptions that affect the reported amounts
      of assets and liabilities and disclosure of
      contingent assets and liabilities at the date of
      the financial statements and the reported
      amounts of revenues and expenses, during the
      reporting period.  Actual results could differ
      from those estimates.
                                                       
      g.  Fair Value of Financial Instruments
                                                       
      The Company's cash and accounts receivable
      represent financial instruments as defined by
      Statement of Financial Accounting Standards No.
      107, Disclosures About Fair Value of Financial
      Instruments.  The carrying value of these
      financial instruments is a reasonable
      approximation of fair value, due to their
      current maturities.
                                                       
      h.  Net Income (Loss) Per Share
                                                       
      Net income (loss) per common share is based upon
      the weighted average number of common shares
      outstanding during the periods presented.
                                                       
3. - RECEIVABLES
                                                       
   The Company sells some of its commercial credit
   accounts to a factor.  Under the agreement, the
   Company sells the receivables at a discount and
   when the receivable is paid the discount is rebated
   to the Company less a fee based upon the length of
   time the receivable is outstanding.  At April 30,
   1997, and April 30, 1998, the outstanding balance
   of commercial credit accounts sold to the factor
   was approximately $258,180 and $517,400
   respectively.  The Company has provided an
   allowance for doubtful accounts of $55,000 at April
   30, 1997 and 1998, which is believed to adequately

<PAGE>
   
               BIOTECHNOLOGY TOOLS, INC.
                                                       
     (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                                                       
            NOTES TO FINANCIAL STATEMENTS
                                                    

                     APRIL 30, 1998
                                                       
4. - LIQUIDITY

The Company's current liabilities exceed current assets
at April 30, 1998 by $ 61,762.  In addition, the
Company is currently in default on its' debentures
payable.  However, current liabilities include $440,578
of deferred payroll due to officers with no definite
payback period, but is classified as current for
financial statement purposes.  Although management
believes that cash generated from operations should
provide the necessary working capital to sustain the
business in the short-term, there can be no assurance
that the Company may not experience adverse market
conditions or other unfavorable events.


5. - INVENTORIES

     Inventories consist of the following:

                                         April 30,
                                      1998       1997

     Raw materials and components   $1,123,702  $1,243,974
     Work in process                   172,932     341,022
     Finished goods                    222,171     191,136

       Total inventories             1,518,805   1,776,132

     Less amount classified as 
       noncurrent                      144,286     168,733

     Current portion               $ 1,374,519 $ 1,607,399

Inventory of $144,286 and $168,733 at April 30, 1998
and 1997, respectively, shown on the balnace sheet as a
noncurrent asset, represents that portion of the
inventory that is not expected to be sold currently.

<PAGE>

                BIOTECHNOLOGY TOOLS, INC.
                                                       
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                                                       
              NOTES TO FINANCIAL STATEMENTS
                                                       

                      APRIL 30, 1998


6. - DEBENTURES PAYABLE
                                              1998       1997

Subordinated debentures, maturing 
  on July 1, 1996, quarterly principal 
  payments plus interest at 12%.  This 
  debt is in default as of October 26, 
  1994 and is classified as currently 
  payable.                                 $63,705     $63,705

7. - INCOME TAXES

     Income taxes included in the Statements of
Operations consist principally of federal and state
income taxes.  The provisions for income taxes for the
fiscal years ended April 30, 1998 and 1997 are as
follows:
                                      1998        1997
     Current:
       Federal                      $    -      $    -
       State                             -           -
     Total                          $    0      $    0

     The tax provision differs from the amounts
computed using the statutory federal income tax rate as
follows:

                                      1998       1997

     Provision (benefit) at 
       statutory federal income
       tax rate                      35.0%      (35.0%)
     Provision (benefit) - 
       state income tax               5.9         (5.9)
     Utilization of net operating 
       loss carryforward           (40.9)             -
     Establishment of net 
       operating loss carryforwards     -          40.9
                                        0             0

     The significant components of net deferred tax
assets and liabilities as of April 30, are as follows:

                                      1998       1997

     Accrued liabilities and other    168,000   160,000
     Valuation allowance            (168,000) (160,000)
          Total deferred tax asset          0         0

<PAGE>

                   BIOTECHNOLOGY TOOLS, INC.
                                                       
    (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                                                       
                NOTES TO FINANCIAL STATEMENTS
                                                       

                       APRIL 30, 1998


8. - COMMITMENTS

     The Company has entered into a lease agreement for
office space.  The lease expires in December 1999.
Additionally, the Company subleases shipping and
warehouse space from an affiliate on a month to month
basis.  Rental expense under the operating lease and
sublease for the fiscal year ended April 30, 1998 was
$77,577.  Remaining commitments under the lease mature
as follows:

     Year ending
     April 30,                        Amount
     1999                           $ 78,107
     2000                             54,886
                                    $ 132,993

9.-  COMMON STOCK

     During 1997, the Company cancelled 157,900 shares
of common stock previously issued to a consultant.  The
shares were cancelled for non-performance of the
service contracted.  Additionally, 154,762 shares of
common stock subscribed to by a former officer were
cancelled for not meeting the terms of the subscription
agreement.

10. - RELATED PARTY TRANSACTIONS

     In 1998 the Company paid Biomatics, owned by its
President David E. Simpson, approximately $47,700 for
services provided to the Company by Biomatics in a
prior year.

     The Company currently rents shipping and warehouse
space from Denvu LLC, a company owned by it's Chairman
and President on a month to month basis.  The rent
expense paid and accrued to Denvu during 1998 amounted
to $9,200.

     The Company bills Denvu for use of its office
supplies, shipping services, equipment and certain
employees' time plus administrative overhead for
measured services performed for Denvu.  These charges
amounted to approximately $82,000 for 1998 .

     Additionally, Denvu reimbursed the Company
approximately $85,000 for payroll services performed by
the Company. The above charges and reimbursement were
recorded as an offset to the various expenses on the
Company's books and have no effect on reported revenues
and expenses or result in any income or loss.

     The Company purchases equipment and services
related to its cryogenic product line from a company
owned by the son of its Chairman.  These purchases in
1998 and 1997 amounted to approximately $90,000 and
$62,000 respectively.

<PAGE>

              BIOTECHNOLOGY TOOLS, INC.
                                                       
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                                                       
           NOTES TO FINANCIAL STATEMENTS
                                                       

                   APRIL 30, 1998
                                                       
11. -   CONCENTRATION OF CREDIT RISK

     Trade receivables potentially subject the Company
to credit risk.  The Company extends credit to its
customers based upon an evaluation of the customer's
financial condition and credit history and generally
does not require collateral.  The Company has
historically incurred minimal credit losses

     The Company's broad range of customers include two
of which account for a significant percentage of sales
volume, as follows:

                                        1998       1997
         Fisher Scientific               25         19
         Nippon Automatic Control         6         11

12. -   SUBSEQUENT EVENTS

     Deferred Savings Plan

     Under section 401(k) of the Internal Revenue Code
of 1986, the Board of Directors adopted, effective May
1, 1998, a tax-qualified deferred compensation plan for
employees of the Company.  Participants may make
contributions which defer up to 20% of their total
salary, up to a maximum for fiscal 1999 of $10,000.
The Company may, at its sole discretion, make cash
contributions each plan year in amounts which match up
to 100% of the salary deferred by the participants.

<PAGE>

             BIOTECHNOLOGY TOOLS, INC.

(FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)

              FINANCIAL STATEMENTS

       FIVE MONTHS ENDED SEPTEMBER 30, 1998

Accountants' Review Report

 Board of Directors and Stockholders
 Biotechnology Tools, Inc.

 We have reviewed the accompanying balance sheet of
Biotechnology Tools, Inc. (Formerly  Research and 
Manufacturing Company Inc.) as of September 30, 1998, 
and the related statements of operations, shareholders' 
equity and cash flows for the five months then ended,
in accordance with Statements on Standards for Accounting 
and Review Services issued by the American Institute of 
Certified Public Accountants.  All information included in 
these financial statements is the representation of the 
management of Biotechnology Tools, Inc.

 A review consists principally of inquiries of Company
personnel and analytical procedures applied to financial 
data.  It is substantially less in scope than an audit in 
accordance with  generally accepted auditing standards, the 
objective of which is the expression of an opinion regarding 
the financial statements taken as a whole. Accordingly, we do 
not express such an  opinion.

 Based on our review, we are not aware of any material
modifications that should be made to the accompanying financial 
statements in order for them to be in conformity with generally
accepted accounting principles.






Kempisty & Company
Certified Public Accountants PC
New York, New York
December 10, 1998

<PAGE>

BIOTECHNOLOGY TOOLS, INC.
(FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
BALANCE SHEET
SEPTEMBER 30, 1998


      ASSETS
 Current Assets
   Cash                                            $    2,700
   Accounts receivable (net of allowance for
       doubtful accounts of $141,160)                 431,762
   Due from factor (Note 3)                           110,517
   Interest receivable from officers                  281,814
   Inventories (Note 5)                             1,521,354
   Prepaid expenses                                    11,878
           Total Current Assets                     2,360,025

 Property, plant and equipment
  Furniture and fixtures                              118,790
   Machinery and equipment                            422,037
                                                      540,827

 Less accumulated depreciation and amortization     (469,244)
                                                       71,583

 Inventories - noncurrent (Note 5)                    169,039

 Other Assets
   Deferred taxes                                     525,000
   Deposits receivable                                 23,278
           Total Other Assets                         548,278
 TOTAL ASSETS                                   $   3,148,925


See notes to financial statements.

<PAGE>

                     BIOTECHNOLOGY TOOLS, INC.
        (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                         BALANCE SHEET
                       SEPTEMBER 30, 1998


      LIABILITIES & STOCKHOLDERS' EQUITY
 Current liabilities:
  Bank overdraft                                 $    49,146
  Accounts payable                                   835,590
  Accrued expenses                                   306,926
  Payroll taxes payable                               34,692
  Customer prepayments                                42,525
  Debentures payable                                  63,705
  Taxes payable                                       25,860
  Deferred revenue                                   135,858
  Due to affiliates                                   73,013
  Due to officers                                    440,578
  Advance from Sherwood Medical                      200,000
  Note payable Ventana Medical                       200,000
  Other                                               13,383
  Capital lease obligations-current portion           10,797
          Total Current Liabilities                2,432,073

 Capital lease obligations (non-current)              53,649

 Commitments (Note 8)

 Stockholders' Equity
  Common stock, $.001 par value, 20,000,000 
    shares authorized, 3,789,100 shares issued 
    and outstanding                                    3,789
  Subscriptions receivable                       (1,172,619)
  Preferred stock $.01 par value, 1,000,000 
    shares authorized, no shares issued or 
    outstanding                                            -
  Additional paid-in capital                        2,190,973
  Retained earnings (deficit)                       (358,940)
          Total Stockholders' Equity                  663,203
 TOTAL LIABILITIES & STOCKHOLDERS' EQUITY         $ 3,148,925

See notes to financial statements.

<PAGE>

                      BIOTECHNOLOGY TOOLS, INC.
        (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                      STATEMENT OF OPERATIONS
           FOR THE FIVE MONTHS ENDED SEPTEMBER 30, 1998

 Net sales                                        $ 2,129,106
 Cost of goods sold                                 1,278,443
 Gross margin                                         850,663

 Operating expenses:
 Selling, general and administrative                1,290,936
 Interest                                              30,408
 Total operating expenses                           1,321,344
 Income (loss) from operations                      (470,681)

 Other income (expense):
 Interest income                                      281,910
 Gain on extinguishment of debt                       196,013
 Gain on sale of equipment                              7,500
 Income (loss) before income taxes                     14,742

 Income tax benefit                                   525,000

 Net income (loss)                                $   539,742

 Net income (loss) per common share               $      0.14

 Average number of common shares                    3,789,100

 Dividends per common share                       $         -

See notes to financial statements.

<PAGE>
<TABLE>
<CAPTION>

                  BIOTECHNOLOGY TOOLS, INC.
     (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
             STATEMENT OF STOCKHOLDERS' EQUITY
       FOR THE FIVE MONTHS ENDED SEPTEMBER 30, 1998


                              Common Stock         Additional                     Retained
                            ($.001) Par Value        Paid-In    Subscription      Earnings
                           Shares       Amount       Capital     Receivable       (Deficit)    Total
<S>                          <C>          <C>           <C>          <C>             <C>         <C>
Balance April 30, 1998   3,789,100      $ 3,789    $ 1,020,699    $ (2,345)     $ (898,682)  $ 123,461

Increase in stock
 subscription                    -            -      1,170,274  (1,170,274)               -          0

Net income                       -            -              -            -         539,742    539,742

Balance September 30, 
  1998                   3,789,100     $  3,789     $2,190,973 $(1,172,619)      $(358,940)  $ 663,203

</TABLE>

See notes to financial statements.

<PAGE>

                      BIOTECHNOLOGY TOOLS, INC.
          (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                      STATEMENT OF CASH FLOWS
            FOR THE FIVE MONTHS ENDED SEPTEMBER 30, 1998

  Cash Flows From Operating Activities:

 Net income                                        $539,742
 Adjustments to reconcile net income 
   to net cash used in operating activities:
 Depreciation and amortization                        8,513
 Increase in allowance for doubtful accounts         86,160
 Increase in reserve for obsolete inventory          41,480
 Gain from debt extinguishment                    (196,013)
 Income tax benefit                               (525,000)
 Changes in operating assets and liabilities:
 Decrease in accounts receivable - trade            349,077
 (Increase) in due from factor                     (12,882)
 (Increase) in interest receivable from officers  (281,814)
 (Increase) in inventories                        (213,068)
 (Increase) in prepaid expenses                    (11,878)
 Decrease in other assets                            10,960
 (Decrease) in bank overdraft                      (17,444)
 (Decrease) in accounts payable and accrued 
   expenses                                        (11,384)
 Increase in payroll taxes payable                   34,692
 Increase in customer prepayments                    42,525
 (Decrease) in deferred revenue                     (6,273)
 (Decrease) in due to affiliates                   (40,907)
 Increase in other liabilities                       13,383
  Cash used in operating activities               (190,131)

  Cash Flows Used in Investing Activities:
 Equipment purchase                                (73,397)
  Cash used in investing activities                (73,397)

  Cash Flows From Financing Activities:
 Loan from Ventana Medical                          200,000
 Capital lease financing                             65,300
 Principal payment on capital lease                   (854)
  Cash provided by financing activities             264,446

 Net decrease in cash                                   918
 Cash, beginning of the year                          1,782
 Cash, end of the year                               $2,700

 Supplementary cash flow information:
   Taxes paid                                      $      -
   Interest paid                                    $30,408

See notes to financial statements.

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.
             NOTES TO FINANCIAL STATEMENTS
                  SEPTEMBER 30, 1998
                           

1.     DESCRIPTION OF BUSINESS

       Biotechnology Tools, Inc. (BTI or the Company) a
Delaware Corporation (formerly Research and
Manufacturing Company, Inc.) manufactures and markets a
wide range of microtorne products, cryogenic hardware
and peripheral equipment, primarily for research and
educational institutions in the United States, Europe
and the Far East.

2.     SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

a.     Revenue Recognition

       Sales are recorded when goods are shipped and
profit is recognized at that time.  Revenue from
service contracts is deferred and taken into income on
a straight-line basis over the period of the contract.

b.     Inventories

       Inventories are stated at the lower of cost or
market.  Cost is computed on the first-in, first-out
basis.  A certain protion of the Company's inventories
consists of parts maintained solely for the repair
and/or replacement of finished products previously
sold.  However, management cannot predict the
anticipated future demand or usage for such
inventories.  these parts are classified as inventory -
noncurrent.

c.     Property, Plant and Equipment

       Property, plant and equipment are stated at
cost.  Depreciation is provided using the straight-line
method over the estimated useful lives of the related
assets as follows:

       Leasehold improvements      life of lease
       Furniture and fixtures            7 years
       Machinery and equipment           5 years

       Expenditures for major renewals and betterments
are capitalized while repairs and maintenance are expensed.

d.     Research and Development Costs

       For financial reporting purposes, all costs of
research and development activities are expensed as incurred.  
For the five months ended September 30, 1998 the

<PAGE>

Company expensed approximately $69,000 for research and development.

e.     Income Taxes

       The Company accounts for income taxes using the
liability method.  Deferred tax assets and liabilities
are determined based on differences between financial
reporting and tax bases of assets and liabilities and
are measured using enacted tax rates and laws ezpected
to be in effect when the differences are expected to
reverse.  Valuation allowances are established when
necessary to reduce the carrying amount of deferred tax
assets to their net realizable value.

f.    Use of Estimates

      The preparation of financial statements in accordance
with generally accepted accounting principles requires
managmeent to make estimates and assumptions that
affect the reported amounts of assets and liabilities
and disclosure of contingent assets and liabilities at
the date of the financial statements and the reported
amounts of revenues and expenses, during the reporting
period.  Actual results could differ from those
estimates.

g.    Fair Value of Financial Instruments

      The Company's cash and accoutns receivable represent
financial insturments as defined by Statement of
Fiancial Accounting Standards No. 107, Disclosures
About Fair Value of Fiancial Instruments.  The
carrying value of these financial instruments is a
reasonable approximation of fair value, due to their
current maturities.

h.     Net Income (Loss) Per Share

       Net income (loss) per common share is based upon
the weighted average number of common shares outstanding 
during the periods presented.

3. -  RECEIVABLES

      The Company sells some of its commercial credit
accounts to a factor.  Under the agreement, the Company 
sells the receivables at a discount and when the receivable
is paid the discount is rebated to the Company less a fee based 
upon the length of time the receivable is outstanding.  At 
September 30, 1998, the outstanding balance of commercial credit 
accounts sold to the factor was approximately $577,000.  The Company 
has provided an allowance for doubtful accounts of $141,160 at 
September 30, 1998, which is believed to adequately cover its credit 
risk related to its accounts receivable.

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
             NOTES TO FINANCIAL STATEMENTS
                           
                  SEPTEMBER 30, 1998


4. -  LIQUIDITY

      The Company's current liabilities exceed current
assets at September 30, 1998 by $72,048.  In addition, 
the Company is currently in default on its' debentures payable.
However, current liabilities include approximately $425,000 of 
deferred payroll due to officers with no definite payback period, 
but is classified as current for financial statement purposes.

      Although management believes that cash generated
from operations should provide the necessary working capital 
to sustain the business in the short-term, there can be no
assurance that the Company may not experience adverse market 
conditions or other unfavorable events.

      During August 1998 the Company and Ventana Acquisitions 
Corporation ("VAC") signed a definitive agreement of merger to 
be effective October 15, 1998.  At the same time the  parent of 
VAC lent the Company $200,000.

5. -  INVENTORIES

      Inventories at September 30, 1998 consist of the
following:

      Raw materials and components          $1,362,595
      Work in process                          396,558
      Finished goods                           194,891
      Reserve for obsolete inventory         (263,651)

        Total inventories                    1,690,393

      Less amount classified as noncurrent     169,039

      Current portion                       $1,521,354

      Inventory of $169,039 at September 30, 1998, shown on the 
balance sheet as a noncurrent asset, represents that portion of 
the inventory that is not expected to be sold currently.

<PAGE>

               BIOTECHNOLOGY TOOLS, INC.
  (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
            NOTES TO FINANCIAL STATEMENTS

                  SEPTEMBER 30, 1998


6. -  DEBENTURES PAYABLE

                                                              1998

      Subordinated debentures, maturing on July 1, 1996,
      quarterly principal payments plus interest at 12%.
      This debt is in default as of October 26, 1994 and 
      is classified as currently payable.                   $63,705

7. -  INCOME TAXES

      The provision (benefit) for income taxes
consisted of the following (in thousands):

                                                         Five months
                                                            ended
                                                         September 30,
                                                             1998
      Current:
        Federal                                              $125
        State                                                  18
      Deferred:
        Federal                                             (585)
        State                                                (83)
                                                           $(525)


      The reconciliation of reported income tax expense
to the amount of income tax expense that would result from 
applying domestic federal statutory tax rates to pretax income 
is as follows (in thousands):

                                                         Five month 
                                                            ended
                                                        September 30,
                                                            1998

      Statutory federal income tax                            $5
      State income tax-net of federal benefit                  1
      Valuation allowance change                           (531)
                                                          $(525)

<PAGE>

                  BIOTECHNOLOGY TOOLS, INC.
     (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                NOTES TO FINANCIAL STATEMENTS

                     SEPTEMBER 30, 1998


7. -  INCOME TAXES (continued)

      The components of deferred tax assets and
liabilities were as follows (in thousands):

                                                    September 30,
                                                        1998
      Deferred tax assets:
        Net operating loss carryforward               $   273
        Officers deferred compensation                    170
        Inventory reserves                                105
        Accounts receivable reserve                        56
        Other liabilities and reserves                     48
        Total deferred assets                         $   652

      Deferred tax liabilities:
        Disqualification of disc                      $   127

      Net deferred tax assets                         $   525

      SFAS No. 109 requires a valuation allowance to be
recorded when it is more likely than not that some or all 
of the deferred tax assets will not be realized.  At April 
30, 1998, a valuation allowance for the full amount of the
net deferred tax asset was recorded because of pre-1998 
losses and uncertainties as to the amount of taxable income 
that would be generated in future years.  Due in large part 
to cost reductions, the Company's taxable income has increased 
substantially.  In the current period, management determined that 
it was more likely than not that future taxable income would be
sufficient to enable the Company to realize all of its deferred tax 
assets.  Accordingly, no valuation allowance has been recorded at
September 30, 1998.

8. -  COMMITMENTS

      The Company has entered into a lease agreement for office 
space.  The lease expires in December 1999.  Additionally, the 
Company subleases shipping and warehouse space from an affiliate 
on a month to month basis.  Rental expense under the operating
lease and sublease for the five months ended September 30, 1998 
was $39,415.  Remaining commitments under the lease mature as
follows:

      Twelve months ending
      September 30,                                       Amount

       1999                                           $    80,746
       2000                                                20,582
                                                      $   101,328

<PAGE>

                   BIOTECHNOLOGY TOOLS, INC.
      (FORMERLY RESEARCH AND MANUFACTURING COMPANY, INC.)
                 NOTES TO FINANCIAL STATEMENTS


                     SEPTEMBER 30, 1998


9. -  RELATED PARTY TRANSACTIONS

      The Company currently rents shipping and warehouse space 
on a month to month  basis from Denvu LLC, a company owned by it's
Chairman and President.  The rent expense paid and accrued to Denvu 
during the period amounted to $7,500.

      The Company bills Denvu for use of its office supplies, shipping 
services, equipment and certain employees' time plus administrative
overhead for measured services performed for Denvu.  These charges 
amounted to approximately $21,000 for the five months ended September 
30, 1998.  Additionally, Denvu reimbursed the Company approximately 
$109,000 for payroll services performed by the Company. The above
charges and reimbursements were recorded as an offset to the various 
expenses on the Company's books, which neither effects reported
revenues and expenses nor results in any income or loss.

      The Company purchases equipment and services related to its 
cryogenic product line from a company owned by the son of its Chairman.
These purchases for the five months ended September 30, 1998 amounted to
approximately $158,000.

10. - STOCK SUBSCRIPTION RECEIVABLE

      On September 29, 1994 certain officers of the Company agreed to 
purchase stock in the Company at $.50 per common share payable in
five years at 6% interest per annum.  Due to a decline in the value 
of the Company shortly thereafter, the Company changed the share 
purchase price to $.001 per share.  As a result of the merger agreement 
the officers agreed to retroactively reinstate their original
purchase price of $.50 per common share plus the 6% interest on the 
unpaid balance to October 14, 1998.  The prior year financial
statements have not been restated to reflect this change because notes 
payable plus accrued interest would have been fully reserved.  The
accrued interest receivable as of September 30, 1998 was $281,814 and 
the note receivable for the stock subscription was $1,172,619.

11. - CONCENTRATION OF CREDIT RISK

      Trade receivables potentially subject the Company to credit risk.  
The Company extends credit to its customers based upon an evaluation
of the customer's financial condition and credit history and generally 
does not require collateral.  The Company has historically incurred 
minimal credit losses.

12. - DEFERRED SAVINGS PLAN

      Under section 401(k) of the Internal Revenue Code of 1986, the 
Board of Directors adopted, effective May 1, 1998, a tax-qualified
deferred compensation plan for employees of the Company.  Participants 
may make contributions which defer up to 20% of their total salary, up 
to a maximum for fiscal 1999 of $10,000.  The Company may, at its
sole discretion, make cash contributions each plan year in amounts which 
match up to 100% of the salary deferred by the participants.

<PAGE>

Item 7(b)

                           
             VENTANA MEDICAL SYSTEMS, INC.
                           
     INTRODUCTION TO UNAUDITED PRO FORMA CONDENSED
           CONSOLIDATED FINANCIAL STATEMENTS
                           
  
  Ventana  Medical  Systems, Inc. ("Ventana")  acquired
Biotechnology Tools, Inc. ("Biotechnology") on  October
14,   1998.   The  accompanying  unaudited  pro   forma
condensed  consolidated balance sheet as  of  September
30,  1998  has  been prepared as if the acquisition  of
Biotechnology had been consummated as of that date. The
accompanying unaudited pro forma condensed consolidated
statements  of  operations for the year ended  December
31,  1997  and for the nine months ended September  30,
1998  have  been  prepared as  if  the  acquisition  of
Biotechnology  had been consummated as  of  January  1,
1997.
  
  The  pro forma information is based on the historical
financial  statements  of  Ventana  and  Biotechnology,
giving  effect  to the transaction under  the  purchase
method   of   accounting  and   the   assumptions   and
adjustments  described  in the  accompanying  Notes  to
Unaudited  Pro  Forma Condensed Consolidated  Financial
Statements.
  
  The  pro  forma  information  is  not  indicative  of
actual  results that would have been achieved  had  the
acquisition  actually been completed as  of  the  dates
indicated, nor is it indicative of the future operating
results or financial position of Ventana. The pro forma
adjustments  are based upon information and assumptions
available  at the time of filing this Form 8-K/A.   The
pro  forma  condensed consolidated financial statements
should  be  read  in  conjunction with  the  historical
financial  statements of Ventana and the related  notes
thereto  previously  filed  with  the  Securities   and
Exchange   Commission  and  the  historical   financial
statements  of  Biotechnology  and  the  related  notes
thereto include elsewhere in this Form 8-K/A.

<PAGE>

             VENTANA MEDICAL SYSTEMS, INC.

  UNAUDITED PRO FORMA CONDENSED CONSOLIDATED BALANCE
                         SHEET
               As of September 30, 1998
                    (in thousands)
                           
                        ASSETS

<TABLE>
<CAPTION>
                           
                              Ventana      Biotechnology     Pro Forma      Pro Forma
                             Historical      Historical     Adjustments    As Adjusted
<S>                             <C>             <C>             <C>           <C>
Current assets:
Cash and cash equivalents     $17,275         $    3         $(3,800)(1)(2)   $13,478
Accounts receivable            11,581            542                -          12,123
Inventories                     8,157          1,521                -           9,678
Other                           3,073            294            (284)(2)        3,083
Total current assets           40,086          2,360          (4,084)          38,362
Property, plant and 
  equipment, net                6,901             72                -           6,973
Intangibles, net                7,637              -            5,146(3)       12,783
Other assets                        -            717            (525)(4)          192
Total assets                  $54,624         $3,149          $   537         $58,310

                           
         LIABILITIES, AND STOCKHOLDERS' EQUITY


Current liabilities:
Accounts payable               $2,374        $   836          $     -         $ 3,210
Other current liabilities       3,224          1,597            1,200(5)        6,021
Total current liabilities       5,598          2,433            1,200           9,231

Long term debt                  1,826             53                -           1,879

Stockholders' equity (deficit)
Common stock                       13              4              (4)(6)           13
Additional paid in capital     78,148          2,191          (2,191)(6)       78,148
Subscriptions receivable            -        (1,173)            1,173(2)            -
Accumulated deficit          (30,532)          (359)              359(6)     (30,532)
Accumulated other 
  comprehensive losses          (429)              -                -           (429)
Total stockholders' 
  equity (deficit)             47,200            663            (663)          47,200
Total liabilities and 
  stockholders' equity        $54,624         $3,149         $    537        $ 58,310

</TABLE>

See accompanying notes.

<PAGE>
             VENTANA MEDICAL SYSTEMS, INC.

UNAUDITED PRO FORMA CONDENSED CONSOLIDATED STATEMENT OF
                      OPERATIONS
                           
         For the Year Ended December 31, 1997
         (in thousands, except per share data)
                           
                           
                       Ventana      Biotechnology    Pro Forma    Pro Forma As
                     Historical     Historical(1)   Adjustments     Adjusted

Net sales              $32,153          $5,226        $   -          $37,379
Cost of goods sold      11,138          2,876             -           14,014
Gross profit            21,015          2,350                         23,365

Operating expenses:
Research and development 3,050            192             -            3,050
Selling, general and 
  administrative        16,953          2,185             -           19,330
Nonrecurring expenses    1,656              -             -            1,656
Amortization of 
  intangibles              509              -           343(6)           852
Loss from operations   (1,153)           (27)         (343)          (1,523)
Interest (expense) 
  income                   781          (136)         (190)(2)           455
Other income                 -            645         (645)(3)             -
Net (loss) income     $  (372)        $   482      $(1,178)        $ (1,068)
Net loss per share 
  basic and diluted   $  (.03)                                       $ (.08)
Weighted average shares 
  outstanding           12,778                                        12,778

See accompanying notes.

<PAGE>

             VENTANA MEDICAL SYSTEMS, INC.

UNAUDITED PRO FORMA CONDENSED CONSOLIDATED STATEMENT OF
                      OPERATIONS
                           
     For the Nine Months Ended September 30, 1998
         (in thousands, except per share data)
                           
                           
                        Ventana    Biotechnology   Pro Forma  Pro Forma As
                       Historical   Historical(1)  Adjustments  Adjusted

Net sales              $33,045         $3,924        $   -       $36,969
Cost of goods sold      10,233          2,259            -        12,492
Gross profit            22,812          1,665            -        24,477

Operating expenses:
Research and development 4,026            133            -         4,159
Selling, general and 
  administrative        16,220          1,822            -        18,042
Amortization of 
  intangibles              382              -          257(6)        639
Income (loss) from 
  operations             2,184          (290)        (257)         1,637
Interest (expense) 
  income                 1,066            219        (425)(4)(2)     860
Other income                 -            736        (736)(5)          -
Net income (loss)     $  3,250        $   665     $(1,418)      $  2,497
Net income per share:
  Basic               $    .24                                  $    .19
  Diluted             $    .22                                  $    .17
Weighted average 
  shares outstanding:
  Basic                 13,301                                    13,301
  Diluted               14,691                                    14,691

See accompanying notes.

<PAGE>

             VENTANA MEDICAL SYSTEMS, INC.

        NOTES TO UNAUDITED PRO FORMA CONDENSED
           CONSOLIDATED FINANCIAL STATEMENTS
         (in thousands, except per share data)

  The  Company  acquired Biotechnology  for  $6,457  on
October 14, 1998.  The pro forma condensed consolidated
balance sheet reflects the Company's financial position
as  if  it had acquired Biotechnology on September  30,
1998.  The pro forma results of operations reflect  the
Company's   operations   as   if   it   had    acquired
Biotechnology on January 1, 1997.  The acquisition  has
been  accounted for as a purchase.  The composition  of
the   consideration  paid  for  Biotechnology  and  the
allocation of the purchase price is presented below:
  
The purchase price for Biotechnology consisted of:
Cash consideration                                    $3,800
Offset for amounts due from management shareholders    1,457
Escrow for contingencies                               1,200
Total purchase price                                  $6,457

The purchase price was allocated as follows:
Tangible net assets                                   $1,311
Goodwill and other intangibles                         5,146
                                                      $6,457

  The   purchase  price  allocation  shown   above   is
preliminary and subject to change.
  
  Intangible  assets  consist  primarily  of  goodwill,
which is amortized over the estimated useful life of 15
years.
  
Balance Sheet Adjustments
(1)     Reflects  the payment by Ventana of  $5,257  of
  cash consideration to Biotechnology shareholders.

(2)     Reflects  the receipt of $1,457  in  cash  from
  Biotechnology  shareholders  for  stock  subscription
  and related accrued interest income receivables.

(3)      Reflects  the  goodwill  resulting  from   the
  purchase  of  Biotechnology,  amortizable   over   15
  years.    The   amount  allocated  to   goodwill   is
  preliminary and subject to change.

(4)      Reflects  the  establishment  of  a  valuation
  allowance for Biotechnology's deferred tax assets.

(5)     Reflects  the contingent consideration  payable
  to  Biotechnology's shareholders in  connection  with
  the purchase by Ventana.

(6)     Reflects  the  elimination  of  Biotechnology's
  equity  accounts as of the balance sheet date,  after
  giving  effect to the transactions noted in  (2)  and
  (4) above.

Statement of Operations Adjustments
(1)     Biotechnology's historical fiscal year ends  on
  April  30.   Biotechnology's  historical  results  of
  operations  have  been adjusted to  a  calendar  year
  basis  to  conform  with  the  reporting  period   of
  Ventana.

(2)     To record the forgone interest income from  the
  net  cash  used  to purchase Biotechnology  ($190  in
  1997,  $143  for  nine  months  ended  September  30,
  1998).

(3)     Biotechnology's historical results  included  a
  gain  on  the  sale  of  a building.   As  such  non-
  recurring  gain  is not indicative of the  operations
  of  the  combined  entity, it has  been  deducted  in
  computing pro-forma income.

<PAGE>

(4)      Biotechnology's  historical  results  included
  interest  income  recognized on  stock  subscriptions
  receivable  from certain officers.   Such  income  is
  not  indicative  of the operations  of  the  combined
  entity  and has therefore been deducted in  computing
  pro-forma income.

(5)      Biotechnology's  historical  results  included
  gains  on  extinguishment of debt  and  the  sale  of
  equipment ($211) and the recognition of deferred  tax
  assets  ($525).  Such other income is not  indicative
  of  the  operations of the combined  entity  and  has
  therefore   been  deducted  in  computing   pro-forma
  income.

(6)     To record the amortization of goodwill (15 year
  life)    established   in   connection    with    the
  Biotechnology purchase.

<PAGE>

                      SIGNATURES

     Pursuant to the requirements of the Securities
Exchange Act of 1934, the Registrant has duly caused
this Report to be signed on its behalf by the
undersigned hereunto duly authorized.


Dated:  December 28, 1998       VENTANA MEDICAL SYSTEMS, INC.



                                By: /s/ Pierre Sice
                                   ---------------------------------------
                                   Pierre Sice
                                   Vice President, Chief Financial Officer, 
                                   Treasurer and Secretary




            CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

     As independent public accountants, we hereby consent to the

incorporation by reference of our report on the financial statements 

of Biotechnology Tools, Inc., dated August 20, 1998 included in this

Amendment No. 1 to Form 8-K, and in Form S-8 (No. 333-16707) pertaining

to the 1996 Stock Option Plan, 1996 Director Option Plan, 1988 Stock

Option Plan and 1996 Employee Stock Purchase Plan of Ventana Medical

Systems, Inc.


                                    /s/ Kempisty & Company

                                    Kempisty & Company

New York, New York
December 28, 1998







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