TECHNOLOGY FUNDING MEDICAL PARTNERS I L P
10-K, 1996-03-25
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<PAGE>
                            UNITED STATES
                   SECURITIES AND EXCHANGE COMMISSION
                         Washington, D.C.  20549

                              FORM 10-K

[X]  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
     SECURITIES EXCHANGE ACT OF 1934

                 For The Fiscal Year Ended December 31, 1995

                                    OR

[ ]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
     SECURITIES EXCHANGE ACT OF 1934

            For the transition period from N/A to N/A
                                           ---    ---

                   Commission File No. 814-124

           TECHNOLOGY FUNDING MEDICAL PARTNERS I, L.P.
           -------------------------------------------
         (Exact name of Registrant as specified in its charter)

          DELAWARE                            94-3166762
- -------------------------------    ------------------------------
(State or other jurisdiction of    (I.R.S. Employer  
incorporation or organization)      Identification No.)

2000 Alameda de las Pulgas, Suite 250
San Mateo, California                                       94403
- ---------------------------------------                  --------
(Address of principal executive offices)               (Zip Code)

                          (415) 345-2200
         --------------------------------------------------
        (Registrant's telephone number, including area code)


Securities registered pursuant to Section 12(b) of the Act:  None
Securities registered pursuant to Section 12(g) of the Act:  
Limited Partnership Units

Indicate by check mark whether the Registrant (1) has filed all 
reports required to be filed by Section 13 or 15(d) of the 
Securities Exchange Act of 1934 during the preceding 12 months (or 
for such shorter period that the Registrant was required to file 
such reports), and (2) has been subject to such filing 
requirements for the past 90 days.
                                                         Yes X No
                                                            ---  ---
Indicate by check mark if disclosure of delinquent filers pursuant 
to Item 405 of Regulation S-K is not contained herein, and will 
not be contained, to the best of registrant's knowledge, in 
definitive proxy or information statements incorporated by 
reference in Part III of this Form 10-K or any amendment to this 
Form 10-K.                                                  [   ]
No active market for the units of limited partnership interests 
("Units") exists, and therefore the market value of such Units 
cannot be determined.
Documents incorporated by reference:  Portions of the Prospectus 
dated May 3, 1993 forming a part of Registration Statement No. 33-
54002, as modified by Cumulative Supplement No. 4 dated January 4, 
1995, filed pursuant to Rule 424(c) of the General Rules and 
Regulations under the Securities Act of 1933 are incorporated by 
reference in Parts I and III hereof.

<PAGE>
                                   PART I

Item 1.  BUSINESS
- ------   --------

Technology Funding Medical Partners I, L.P. (the 
"Partnership") is a limited partnership organized under 
the laws of the State of Delaware in September 1992 and 
was inactive until it commenced the sale of Units in May 
1993.  The purpose of the Partnership is to make venture 
capital investments in emerging growth companies as 
described in the "Introductory Statement" and "Business 
of the Partnership" sections of the Prospectus dated May 
3, 1993.  The Partnership has elected to be a business 
development company under the Investment Company Act of 
1940, as amended (the "Act"), and operates as a 
nondiversified investment company as that term is defined 
in the Act.  Additional characteristics of the 
Partnership's business are discussed in the "Risk 
Factors" and "Conflicts of Interest" sections of the 
Prospectus, which sections are also incorporated herein 
by reference.  The Partnership Agreement provides that 
the Partnership will terminate December 31, 2002, subject 
to the right of the individual general partners to extend 
the term for up to two additional two-year periods.

Item 2.  PROPERTIES
- ------   ----------

The Registrant has no material physical properties.

Item 3.  LEGAL PROCEEDINGS
- ------   -----------------

There are no material pending legal proceedings to which 
the Registrant is party or of which any of its property 
is the subject, other than ordinary routine litigation 
incidental to the business of the Partnership.

Item 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS
- ------   ---------------------------------------------------

The initial meeting of Limited Partners of the 
Partnership was held on September 8, 1995 pursuant to a 
Notice of Meeting dated July 17, 1995.  At the meeting 
proxies submitted by Limited Partners documented that the 
Limited Partners elected the three individual general 
partners, elected the two Managing General Partners, and 
ratified the selection of KPMG Peat Marwick LLP as 
independent certified accountants for the fiscal year 
ended December 31, 1995.  The number of Units voted in 
favor, against and abstained for each matter submitted 
are as follows:
<TABLE>
<CAPTION>
                                 For  Against  Abstained
                                 ---  -------  ---------
<S>                            <C>        <C>       <C> 

Individual general partners    40,987        0        848
Managing General Partners      41,087        0        748
Ratification of KPMG Peat 
  Marwick LLP                  39,666        0      2,169

         </TABLE>

PART II

Item 5.  MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED 
- ------   -------------------------------------------------
         STOCKHOLDER MATTERS
         -------------------

        (a) There is no established public trading market for the 
            Units.

        (b) At December 31, 1995, there were 829 record holders 
            of Units.

        (c) The Registrant, being a partnership, does not pay 
            dividends.  Cash distributions, however, may be made 
            to the partners in the Partnership pursuant to the 
            Registrant's Partnership Agreement.

Item 6.  SELECTED FINANCIAL DATA
- ------   -----------------------

<TABLE>
<CAPTION>
                                  For the Years Ended and As of
                                           December 31, 
                                 --------------------------------
                                 1995           1994         1993
                                 ----           ----         ----

<S>                           <C>           <C>         <C>       

Interest income               $  245,800       132,394     16,706
Net realized loss               (328,499)     (188,769)  (113,431)
Change in net unrealized 
 fair value of
 equity investments               (8,447)           --         --
Net loss                        (336,976)     (188,769)  (113,431)
Net realized loss
  per Unit                            (4)           (4)       (12)
Total assets	                   6,057,701     4,876,769  2,597,416
Distributions declared           (77,789)     (132,394)   (16,706)

</TABLE>

Refer to the financial statement notes entitled "Summary 
of Significant Accounting Policies" and "Allocation of 
Profits and Losses" for a description of the method of 
calculation of net realized income (loss) per Unit.

Item 7.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL 
- ------   -------------------------------------------------
CONDITION AND RESULTS OF OPERATIONS
- -----------------------------------

Liquidity and Capital Resources
- -------------------------------

The Partnership commenced the offering of limited 
partnership units ("Units") in May 1993.  In October 
1993, the minimum number of Units required by the 
Partnership Agreement to commence operations were sold.  
From inception through May 3, 1995, the sale of Units 
generated cash of $7,929,844 and the Managing General 
Partners contributed cash of $7,934.  In connection with 
the capital raised, the Partnership expended $1,073,613 
in syndication fees and capitalized $40,000 in 
organizational costs.  Such fees are applied to the 
capital accounts of the partners while organizational 
costs are amortized over a 60 month period.
During 1995, net cash used by operations totaled 
$313,558.  The Partnership paid management fees of 
$201,581 to the Managing General Partners and paid 
related parties for operating expenses of $233,347.  In 
addition, $31,575 was paid to the individual general 
partners as compensation for their services.  The 
Partnership paid other operating expenses of $92,428 and 
received $245,373 in interest income.
During 1995, the Partnership purchased $819,131 in equity 
investments primarily in the biotechnology, diagnostic 
equipment and health information systems industries.
During 1995, distributions of $123,713 for interest 
earned during the offering period were paid.
At December 31, 1995, the Partnership was committed to 
fund an additional $212,250 in equity investments and 
venture capital limited partnership investments.
During 1995, Khepri Pharmaceuticals, Inc. was acquired by 
Arris Pharmaceuticals, Inc.  Although the Partnership's 
holdings are subject to selling restrictions, the 
acquisition indicates potential future liquidity for this 
investment.
Cash and cash equivalents at December 31, 1995 were 
$3,948,745.  Interest income earned on short-term 
investments and operating cash reserves are expected to 
be adequate to fund Partnership operations through the 
next twelve months.
Results of Operations
- ---------------------

1995 compared to 1994
- ---------------------

Net loss was $336,976 for 1995 compared to $188,769 
during the same period in 1994. The increase in net loss 
was primarily due to a $134,288 increase in total 
operating expenses as well as a $116,273 increase in 
management fees.  These changes were partially offset by 
a $113,406 increase in interest income. 

Total operating expenses were $330,590 and $196,302 for 
1995 and 1994, respectively.  As explained in Note 2, the 
Partnership may not reimburse the Managing General 
Partners for annual operating expenses that aggregate 
more than 3% of total Limited Partner capital 
contributions.  The limitation is calculated over an 
operating year beginning May 3.  For 1995, the Managing 
General Partners absorbed $77,958 in such expenses.  In 
addition, the 1995 actual operating expenses included 
additional administrative and investor services expense 
of $52,403 not previously recognized by the Partnership. 
In 1994, operating expenses of $89,086 were transferred 
to the General Partners; this amount was not reflected as 
operating expenses in 1994 as it represented a contingent 
liability of the Partnership.  Had the limitation not 
been in effect and the additional expenses been recorded 
in prior years, and had the transfer not occurred in 
1994, total operating expenses for 1995 and 1994 would 
have been $293,672 and $308,624, respectively.  The 
decrease was primarily due to lower overall portfolio 
activity.
The Partnership recorded management fees of $204,134 and 
$87,861 during 1995 and 1994, respectively.  Management 
fees are equal to two percent of the total Limited 
Partner capital contributions for the first year of 
Partnership operations through the sixth year.  Pursuant 
to the Partnership Agreement, a full first year fee is 
paid to the Managing General Partners as each additional 
Limited Partner is admitted to the Partnership, 
regardless of the date the Limited Partner is admitted.  
Management fees increased in 1995 due to the sale of new 
Units.
The Partnership recorded interest income of $245,800 and 
$132,394 for 1995 and 1994, respectively.  The increase 
was mainly due to a higher average cash and cash 
equivalents balance in 1995 compared to 1994 from the 
sale of new Units.
Given the inherent risk associated with the business of 
the Partnership, the future performance of the portfolio 
company investments may significantly impact future 
operations.

1994 compared to 1993
- ---------------------

Net loss was $188,769 in 1994 compared to $113,431 in 
1993. The increase in net loss was mostly due to a 
$140,327 increase in operating expenses, and a $26,199 
increase in management fees, partially offset by a 
$115,688 increase in interest income.
The primary reason for the above income and expense 
increases was due to a full year of Partnership 
operations in 1994 compared to only a quarter year of 
operations in 1993 as the Partnership's commencement date 
was October 8, 1993.  Discussion of additional increases 
follows.
Operating expenses were $196,302 in 1994 compared to 
$55,975 in 1993.  Such expenses were expected to increase 
as investment activities and the number of partners 
increased.
Management fees totaled $87,861 in 1994 compared to 
$61,662 in 1993.  Management fees were expected to 
increase as the Partnership continued to sell Units.
Interest income was $132,394 in 1994 compared to $16,706 
in 1993.  The increase was due to higher cash and cash 
equivalents balances in 1994 as the Partnership sold more 
Units.

Item 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
- ------   -------------------------------------------

The financial statements of the Registrant are set forth 
in Item 14.

Item 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON 
- ------   ------------------------------------------------
ACCOUNTING AND FINANCIAL DISCLOSURE
         -----------------------------------

Registrant has reported no disagreements with its 
accountants on matters of accounting principles or 
practices or financial statement disclosure.

                                PART III

Item 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT
- -------  --------------------------------------------------

As a partnership, the Registrant has no directors or 
executive officers.  The Management Committee is 
responsible for the management and administration of the 
Partnership.  The members of the Management Committee 
consist of three individual general partners and a 
representative from each of Technology Funding Ltd., a 
California limited partnership ("TFL"), and its wholly-
owned subsidiary, Technology Funding Inc., a California 
corporation ("TFI").  TFL and TFI are the Managing 
General Partners.  Information concerning the ownership 
of TFL and the business experience of the key officers of 
TFI and the partners of TFL is incorporated by reference 
from the sections entitled "Management of the Partnership 
- - The Managing General Partners" and "Management of the 
Partnership - Key Personnel of the Managing General 
Partners" in the Prospectus as modified by Cumulative 
Supplement No. 4 dated January 4, 1995, which are 
incorporated herein by reference.  

Item 11. EXECUTIVE COMPENSATION
- -------  ----------------------

As a partnership, the Registrant has no officers or 
directors.  In 1995, the Partnership incurred $204,134 in 
management fees.  The fees are designed to compensate the 
Managing General Partners for General Partner Overhead 
incurred in performing management duties for the 
Partnership through December 31, 1995.  General Partner 
Overhead (as defined in the Partnership Agreement) 
includes the General Partners' share of rent and 
utilities, and certain salaries and benefits paid by the 
Managing General Partners in performing their obligations 
to the Partnership.  As compensation for their services, 
the individual general partners each receive $6,000 
annually beginning on the Commencement Date, plus $1,000 
for each attended meeting of the individual general 
partners, and related expenses.  For the year ended 
December 31, 1995, $31,575 of such fees were paid.

Item 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
- -------  ---------------------------------------------------
MANAGEMENT
- ----------

Not applicable.  No Limited Partner beneficially holds 
more than 5% of the aggregate number of Units held by all 
Limited Partners, and neither the General Partners nor 
any of their officers, directors or partners own any 
Units.  The three individual general partners each own 20 
Units.  The General Partners control the affairs of the 
Partnership pursuant to the Partnership Agreement.

Item 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
- -------  ----------------------------------------------

The Registrant, or its investee companies, have engaged 
in no transactions with the General Partners or their 
officers and partners other than as described above, in 
the notes to the financial statements, or in the 
Partnership Agreement.


<PAGE>
                                   PART IV


Item 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON 
- -------  -------------------------------------------------------
         FORM 8-K
         --------

         (a)  List of Documents filed as part of this Annual 
Report on Form 10-K

             (1)  Financial Statements - the following financial 
statements are filed as a part of this Report:

                  Independent Auditors' Report
                  Balance Sheets as of December 31, 1995
                    and 1994
                  Statements of Operations for the years
                    ended December 31, 1995, 1994 and 1993
                  Statements of Partners' Capital for the years
                    ended December 31, 1995, 1994 and 1993
                  Statements of Cash Flows for the years
                    ended December 31, 1995, 1994 and 1993
                  Notes to Financial Statements

             (2)  Financial Statement Schedules

All schedules have been omitted because they are 
not applicable or the required information is 
included in the financial statements or the 
notes thereto.

             (3)  Exhibits

Registrant's Amended and Restated Limited 
Partnership Agreement (incorporated by reference 
to Exhibit A to Registrant's Prospectus dated 
May 3, 1993 included in Registration Statement 
No. 33-54002 filed pursuant to Rule 424(b) of 
the General Rules and Regulations under the 
Securities Act of 1933).

         (b)  Reports on Form 8-K

              No reports on Form 8-K were filed by the Registrant 
during the year ended December 31, 1995.

         (c)  Financial Data Schedule for the year ended and as of 
December 31, 1995 (Exhibit 27).

<PAGE>
                   INDEPENDENT AUDITORS' REPORT
                   ----------------------------

The Partners
Technology Funding Medical Partners I, L.P.:


We have audited the accompanying balance sheets of Technology 
Funding Medical Partners I, L.P. (a Delaware limited partnership) 
as of December 31, 1995 and 1994, and the related statements of 
operations, partners' capital, and cash flows for each of the 
years in the three-year period ended December 31, 1995.  These 
financial statements are the responsibility of the Partnership's 
management.  Our responsibility is to express an opinion on these 
financial statements based on our audits.

We conducted our audits in accordance with generally accepted 
auditing standards.  Those standards require that we plan and 
perform the audit to obtain reasonable assurance about whether the 
financial statements are free of material misstatement.  An audit 
includes examining, on a test basis, evidence supporting the 
amounts and disclosures in the financial statements.  Our 
procedures included confirmation of certain securities owned, by 
correspondence with the individual investee companies, and a 
physical examination of those securities held by a safeguarding 
agent as of December 31, 1995 and 1994.  An audit also includes 
assessing the accounting principles used and significant estimates 
made by management, as well as evaluating the overall financial 
statement presentation.  We believe that our audits provide a 
reasonable basis for our opinion.

In our opinion, the financial statements referred to above present 
fairly, in all material respects, the financial position of 
Technology Funding Medical Partners I, L.P. as of December 31, 
1995 and 1994, and the results of its operations and its cash 
flows for each of the years in the three-year period ended 
December 31, 1995 in conformity with generally accepted accounting 
principles.



San Francisco, California                    KPMG Peat Marwick LLP
March 22, 1996

<PAGE>

BALANCE SHEETS
- --------------

<TABLE>
<CAPTION>
                                                  December 31,
                                           ----------------------
                                              1995          1994
                                              ----          ----
<S>                                        <C>           <C>

ASSETS

Equity investments (cost basis of
 $2,094,559 and $1,275,001 in 1995
 and 1994, respectively)                    $2,086,082  1,275,001

Cash and cash equivalents                    3,948,745  3,571,768

Organizational costs (net of accumulated
 amortization of $18,000 and $10,000 
 in 1995 and 1994, respectively)                22,000     30,000

Other Assets                                       874         --
                                             ---------  ---------

     Total                                  $6,057,701  4,876,769
                                             =========  =========

LIABILITIES AND PARTNERS' CAPITAL

Accounts payable and accrued expenses       $   20,115     19,216

Due to related parties                          39,486     32,143

Distributions payable                               --     45,924
                                              --------  ---------

     Total liabilities                          59,601     97,283

Commitments (Notes 2 and 7)

Partners' capital:
  Limited Partners 
   (Units outstanding of 79,716 and 
    60,640 in 1995 and 1994, respectively)   6,011,161  4,780,868
  General Partners                              (4,584)    (1,382)
  Net unrealized fair value decrease
   from cost of equity investments              (8,477)        --
                                             ---------  ---------

     Total partners' capital                 5,998,100  4,779,486
                                             ---------  ---------

     Total                                  $6,057,701  4,876,769
                                             =========  =========
</TABLE>

See accompanying notes to financial statements.

<PAGE>
STATEMENTS OF OPERATIONS
- ------------------------

<TABLE>
<CAPTION>

                                 For the Years Ended December 31,
                                 --------------------------------
                                 1995          1994          1993
                                 ----          ----          ----
<S>                          <C>            <C>           <C>

Interest income              $ 245,800       132,394       16,706

Costs and expenses:
  Management fees              204,134        87,861       61,662
  Individual general 
   partners' compensation       31,575        29,000       10,500
  Amortization of
   organizational costs          8,000         8,000        2,000
  Operating expenses:
    Administrative and 
     investor services         252,565       118,544       29,499
    Investment operations       78,333        48,581        4,067
    Computer services           29,172        10,357        4,409
    Professional fees           48,478        18,820       18,000
    Expenses absorbed by
     General Partners          (77,958)           --           --
                               -------       -------       ------

       Total operating
         expenses              330,590       196,302       55,975
                               -------       -------       ------

         Total costs and
           expenses            574,299       321,163      130,137
                               -------       -------      -------

Net realized loss             (328,499)     (188,769)    (113,431)

Change in net unrealized fair
 value of equity investments    (8,477)           --           --
                               -------       -------      -------

Net loss                     $(336,976)     (188,769)    (113,431)
                               =======       =======      =======

Net realized loss per Unit   $      (4)           (4)         (12)
                               =======       =======      =======
</TABLE>
See accompanying notes to financial statements.


<PAGE>
STATEMENTS OF PARTNERS' CAPITAL
- -------------------------------
<TABLE>
<CAPTION>
For the years ended December 31, 1995, 1994 and 1993:

                                                          Net Unrealized 
                                                       Fair Value Decrease
                               Limited      General    from Cost of Equity
                               Partners     Partners        Investments          Total
                               --------     --------   -------------------     -------


<S>                            <C>            <C>                <C>         <C>     

Partners' capital,
 December 31, 1992             $      100          2             --               102

Sales of partnership
 interests                      3,083,000      3,081             --         3,086,081

Syndication fees                 (405,754)    (1,296)            --          (407,050)

Distributions of Offering
 Period income                    (16,539)      (167)            --           (16,706)
 
Net realized loss                (112,297)    (1,134)            --          (113,431)
                                ---------      -----          -----          ---------

Partners' capital,
 December 31, 1993              2,548,510        486             --         2,548,996

Sales of partnership interests  2,980,900      2,983             --         2,983,883

Syndication fees                 (430,591)    (1,639)            --          (432,230)

Distributions of Offering
 Period income                   (131,070)    (1,324)            --          (132,394)
 
Net realized loss                (186,881)    (1,888)            --          (188,769)
                                ---------      -----          -----         ---------

Partners' capital,
 December 31, 1994              4,780,868     (1,382)            --         4,779,486

Sales of partnership
 interests                      1,865,844      1,868             --         1,867,712

Syndication fees                 (233,326)    (1,007)            --          (234,333)

Distributions of Offering
 Period income                    (77,011)      (778)            --           (77,789)

Change in net unrealized fair
 value of equity investments           --         --         (8,477)           (8,477)

Net realized loss                (325,214)    (3,285)                        (328,499)
                                ---------      -----          -----          --------

Partners' capital,
 December 31, 1995             $6,011,161     (4,584)        (8,477)        5,998,100
                                =========      =====          =====         =========


</TABLE>
See accompanying notes to financial statements.



<PAGE>

STATEMENTS OF CASH FLOWS
- ------------------------

<TABLE>
<CAPTION>

                                             For the Years Ended December 31,
                                             --------------------------------
                                             1995          1994          1993
                                             ----          ----          ---- 
<S>                                      <C>            <C>              <C>


Cash flows from operating activities:
  Interest received                      $   245,373       132,394        16,706
  Cash paid to vendors                       (92,428)      (74,558)       (1,094)
  Cash paid to related parties              (466,503)     (218,960)      (95,329)
                                           ---------     ---------     ---------

    Net cash used by operating activities   (313,558)     (161,124)      (79,717)
                                           ---------     ---------     ---------

Cash flows from investing activities:
  Purchase of equity investments            (819,131)   (1,175,001)     (100,000)
                                           ---------     ---------     ---------

    Net cash used by investing activities   (819,131)   (1,175,001)     (100,000)
                                           ---------     ---------     ---------

Cash flows from financing activities:
  Proceeds from sales of limited 
    partnership interests                  1,865,844     2,980,900     3,083,000
  General Partners' capital contribution       1,868         2,983         3,081
  Distribution of Offering Period income    (123,713)     (103,176)           --
  Payments for syndication fees and
    organizational costs                    (234,333)     (432,230)     (447,050)
                                           ---------     ---------     ---------

    Net cash provided by financing
     activities                            1,509,666     2,448,477     2,639,031
                                           ---------     ---------     ---------

Net increase in cash and 
 cash equivalents                            376,977     1,112,352     2,459,314

Cash and cash equivalents 
 at beginning of year                      3,571,768     2,459,416           102
                                           ---------     ---------     ---------

Cash and cash equivalents 
 at end of year                          $ 3,948,745     3,571,768     2,459,416
                                           =========     =========     =========

Reconciliation of net loss to net cash
 used by operating activities:

Net loss                                 $  (336,976)     (188,769)     (113,431)

Adjustments to reconcile net loss
 to net cash used by operating activities:

   Amortization of organizational costs        8,000         8,000         2,000
   Change in net unrealized fair value
    of equity investments                      8,477            --            --

Changes in:
   Accounts payable and accrued expenses         899         1,210        18,006
   Due to related parties                      7,343        18,435        13,708
   Other, net                                 (1,301)           --            --
                                           ---------     ---------     ---------

Net cash used by operating activities    $  (313,558)     (161,124)      (79,717)
                                           =========     =========     =========


</TABLE>
See accompanying notes to financial statements.



<PAGE>

NOTES TO FINANCIAL STATEMENTS
- -----------------------------

1.  Summary of Significant Accounting Policies
    ------------------------------------------

Organization
- ------------

Technology Funding Medical Partners I, L.P. (the "Partnership") is 
a limited partnership organized under the laws of the State of 
Delaware in September 1992.  The purpose of the Partnership is to 
make venture capital investments in emerging growth companies.  The 
Partnership elected to be a business development company under the 
Investment Company Act of 1940, as amended (the "Act"), and 
operates as a nondiversified investment company as that term is 
defined in the Act.  The Managing General Partners are Technology 
Funding Ltd. ("TFL"), and Technology Funding Inc. ("TFI"), a 
wholly-owned subsidiary of TFL.  There are also three individual 
general partners.  A wholly-owned subsidiary of TFI, Technology 
Funding Securities Corporation ("TFSC") was the dealer-manager for 
the offering.

For the period from September 1992 through May 3, 1993, the 
Partnership was inactive.  The Partnership's registration statement 
was declared effective by the Securities and Exchange Commission on 
May 3, 1993, and the Partnership began selling units of limited 
partnership interests ("Units") in May 1993.

On October 8, 1993, the Commencement Date, the minimum number of 
Units required to begin Partnership operations (12,000) had been 
sold.  Then, on May 3, 1995, the offering terminated with 79,716 
Units sold.  The Partnership Agreement provides that the 
Partnership will continue until December 31, 2002, unless further 
extended for up to two additional two-year periods from such date 
if the individual general partners so determine or unless sooner 
dissolved.

Preparation of Financial Statements and Use of Estimates
- --------------------------------------------------------

These financial statements have been prepared on the accrual basis 
of accounting in accordance with generally accepted accounting 
principles.  This required management to make estimates and 
assumptions that affect the reported amounts of assets and 
liabilities and disclosure of contingent assets and liabilities at 
the date of the financial statements and the reported amounts of 
revenues and expenses during the reporting period.  Actual results 
could differ from those estimates.

The financial statements include non-marketable investments of 
$2,086,082 and $1,275,001 (35% and 27% of partners' capital) as of 
December 31, 1995 and 1994, respectively, whose values have been 
estimated by the Managing General Partners in the absence of 
readily ascertainable market values.  Because of the inherent 
uncertainty of valuation, those estimated values may differ 
significantly from the values that would have been used had a ready 
market for investments existed, and the differences could be 
material.  In addition, for certain publicly traded investments 
that may not be marketable due to selling restrictions, the 
Managing General Partners have applied an illiquidity discount of 
25% in determining fair value as mentioned below.

Cash and Cash Equivalents
- -------------------------

Cash and cash equivalents are principally comprised of cash 
invested in demand accounts, money market instruments and 
commercial paper and are stated at cost plus accrued interest.  The 
Partnership considers all money market, commercial paper and short-
term investments with an original maturity of three months or less 
to be cash equivalents.

Syndication Fees
- ----------------

Syndication fees, which consist of commissions and certain 
organizational and offering costs, are deducted from the partners' 
capital accounts.  Pursuant to the Partnership Agreement, selling 
commissions are allocated solely to the Limited Partners.  All 
other syndication fees are allocated 99% to the Limited Partners 
and 1% to the Managing General Partners.  Syndication fees are not 
deductible for income tax purposes.  Such fees may result in a 
reduction of any gain (or an increase in any loss) realized for tax 
purposes by the partners upon dissolution of the Partnership or a 
transfer of their interests.

Organizational Costs
- --------------------

Organizational costs of $40,000 are amortized over 60 months, using 
the straight-line method.

Provision for Income Taxes
- --------------------------

No provision for income taxes has been made by the Partnership, as 
the Partnership is not directly subject to taxation.  The partners 
are to report their respective shares of Partnership income or loss 
on their individual tax returns.

The accompanying financial statements are prepared using generally 
accepted accounting principles which may not equate to tax 
accounting.  The difference in the total book and tax cost basis as 
of December 31, 1995 is not material.

Net Realized Income (Loss) Per Unit
- -----------------------------------

Net realized income (loss) per Limited Partner Unit is calculated 
by dividing the weighted average number of Limited Partner Units 
outstanding for the years ended December 31, 1995, 1994 and 1993, 
of 74,425, 44,272 and 9,589, respectively, into total net realized 
loss allocated to the Limited Partners.  The Managing General 
Partners contributed 0.1% of total Limited Partner capital 
contribution and did not receive any Partnership units.

Equity Investments
- ------------------

The Partnership's method of accounting for investments, in 
accordance with generally accepted accounting principles, is the 
fair value basis used for investment companies.  The fair value of 
Partnership equity investments is their initial cost basis with 
changes as noted below:

The fair value for publicly-traded equity investments (marketable 
equity securities) is based upon the five-day-average closing sales 
price or bid/ask price that is available on a national securities 
exchange or over-the-counter market.  Certain publicly-traded 
equity investments may not be marketable due to selling 
restrictions.  For publicly-traded equity investments with selling 
restrictions, an illiquidity discount of 25% is applied when 
determining the fair value.  Sales of equity investments are 
recorded on the trade date.  The basis on which cost is determined 
in computing realized gains or losses is generally specific 
identification.

Other equity investments, which are not publicly traded, are 
generally valued utilizing pricing obtained from the most recent 
round of third-party financings.  Valuation is estimated quarterly 
by the Managing General Partners.  Included in equity investments 
are convertible and subordinated notes receivable as repayment of 
these notes generally occur through conversion into equity 
investments.

Venture capital limited partnership investments are initially 
recorded at cost and reduced for distributions that are a return of 
capital.  Distributions from limited partnership cumulative 
earnings are reflected as realized gains by the Partnership.

Equity and venture capital limited partnership investments with 
temporary changes in fair value result in increases or decreases to 
the unrealized fair value of equity investments.  The cost basis 
does not change.  In the case of an other than temporary decline in 
value below cost basis, an appropriate reduction in the cost basis 
is recognized as a realized loss with the fair value being adjusted 
to match the new cost basis.  Adjustments to fair value basis are 
reflected as "Change in net unrealized fair value of equity 
investments."  Cost basis adjustments are reflected as "Realized 
losses from investment write-downs" or "Net realized loss from 
venture capital limited partnership investments" on the Statements 
of Operations.

2.  Related Party Transactions
    --------------------------

Related party costs are included in costs and expenses shown on the 
Statements of Operations and Partners' Capital.  For the years 
ended December 31, 1995, 1994 and 1993, related party costs were as 
follows:

<TABLE>
<CAPTION>
                                       1995        1994       1993
                                       ----        ----       ----
  <S>                                <C>         <C>        <C>

  Management fees                    $204,134     87,861     61,662
  Syndication fees                    234,333    432,230    407,050
  Individual general partners'
   compensation                        31,575     29,000     10,500
  Amortization of organizational
   costs                                8,000      8,000      2,000
  Reimbursable operating expenses:
    Administrative and investor 
     services                         216,113     66,165     28,399
    Investment operations              70,810     44,012      4,067
    Computer services                  29,172     10,357      4,409
    Expenses absorbed by
     General Partners                 (77,958)        --         --
</TABLE>

Management fees are equal to two percent of the total Limited 
Partner capital contributions for the first year of Partnership 
operations through the sixth year.  Beginning in the seventh year, 
the management fee will decline by ten percent per year from the 
initial two percent.  Management fees compensate the Managing 
General Partners solely for General Partner overhead (as defined in 
the Partnership Agreement) incurred in supervising the operation 
and management of the Partnership and the Partnership's 
investments.  Pursuant to the Partnership Agreement, a full first 
year fee is paid to the Managing General Partners as each 
additional Limited Partner is admitted to the Partnership, 
regardless of the date the Limited Partner is admitted.  Management 
fees payable were $13,216 and $10,663 at December 31, 1995 and 
1994, respectively.

The Partnership reimburses the Managing General Partners for 
organizational and offering expenses (up to five percent of the 
total Limited Partner capital contributions) incurred in connection 
with organizing the Partnership and the offering of Units thereof.  
Such reimbursements have been reflected in the Statements of 
Partners' Capital as syndication fees except for $40,000 of 
organizational costs which have been capitalized.

Also included in the syndication fees are commissions and fees paid 
to TFSC, the dealer-manager.  During the year ended December 31, 
1995, the Partnership paid commissions and fees of $133,618 of 
which $118,711 was reallowed to participating broker-dealers; in 
1994, the Partnership paid $268,281 of which $227,035 was 
reallowed.  In addition, the Partnership also paid $7,424 and 
$14,907 in 1995 and 1994, respectively, to TFSC for due diligence 
expenses (up to one-half of one percent of total limited partners' 
capital contributions) that TFSC paid to unaffiliated broker-
dealers.

The Partnership reimburses the Managing General Partners for 
operating expenses incurred in connection with the business of the 
Partnership.  Reimbursable operating expenses include expenses 
(other than Organizational and Offering expenses and General 
Partner overhead), such as administrative and investor services, 
investment operations, and computer services.  During late 1995, 
operating cost allocations to the Partnership were reevaluated.  
The Managing General Partners determined that they had not fully 
recovered allocable overhead as permitted by the Partnership 
Agreement.  As a result, the Partnership was charged additional 
administrative and investor services costs of $52,403 that was not 
previously recognized by the Partnership.  This amount consisted of 
$26,613, $23,236 and $2,554 for 1995, 1994, and 1993, respectively.  
If this charge had been recorded in prior years, operating 
expenses, before expenses absorbed by General Partners, would have 
been $382,758, $219,538 and $58,529 for 1995, 1994, and 1993, 
respectively.  The increase of $163,220 in 1995 from 1994 was due 
to the recognition of the $89,086 contingent liability at December 
31, 1994 based on additional Units sold in 1995 as discussed below.  
The $161,009 increase in 1994 from 1993 was due to a full year of 
Partnership operations in 1994 compared to only one quarter year of 
operations in 1993.  Amounts due to related parties for such 
expenses were $26,270 and $21,480 at December 31, 1995 and 1994, 
respectively.

Pursuant to the Partnership Agreement, the Partnership may not pay 
or reimburse the Managing General Partners for operational costs 
that aggregate more than 3% of total Limited Partner capital 
contributions of the Partnership in each year through the first 
five years of operations after the termination of Unit sales, and 
1.5% in any year thereafter.  In 1995, the Partnership recognized 
$55,975 of the $89,086 contingent liability at December 31, 1994 
based on additional Limited Partner capital contributions received 
by the end of the offering period, May 3, 1995.  The remaining 
balance of $33,111, including additional expenses of $44,847 were 
absorbed by the Managing General Partners.

As compensation for their services, the individual general partners 
each received $6,000 annually beginning on the Commencement Date, 
plus $1,000 for each of the management committee meetings attended 
and related expenses.  The three individual general partners each 
own 20 Units.

Under the terms of a computer service agreement, the Partnership 
recognized charges from Technology Administrative Management, a 
division of TFL, for its share of computer support costs.  These 
amounts are included in computer services expense.

3.  Allocation of Profits and Losses
    --------------------------------

Net realized profit and loss of the Partnership are allocated based 
on the beginning of year partners' capital balances as follows:

(a).  Profits:

(i)  first, to those partners with deficit capital account 
balances in proportion to such deficits until the 
deficits have been eliminated; then

(ii) second, to the partners as necessary to offset net 
losses and sales commissions previously allocated to 
such partners; then

(iii)third, 75% to the Limited Partners as a group in 
proportion to the number of Units, 5% to the Limited 
Partners in proportion to the Unit months of each 
Limited Partner, and 20% to the Managing General 
Partners.  Unit months are the number of half months a 
Unit would be outstanding if held from the date the 
original holder of such Unit was deemed admitted into 
the Partnership until the termination of the offering 
of Units.

(b).  Losses:

(i)  first, to the partners as necessary to offset net 
profits previously allocated to the partners under 
(a)(iii) above plus losses from unaffiliated venture 
capital limited partnership investments; then

(ii) 99% to the Limited Partners as a group and 1% to the 
Managing General Partners.


Losses allocable to Limited Partners in excess of their capital 
account balances will be allocated to the Managing General 
Partners.  Net profits thereafter, otherwise allocable to those 
Limited Partners, are allocated to the Managing General Partners to 
the extent of such losses.  

As indicated above, losses from unaffiliated venture capital 
limited partnership investments are allocated pursuant to section 
(b).  Gains are allocated first to offset previously allocated 
losses pursuant to (b)(i) above, and then 99% to Limited Partners 
and 1% to the Managing General Partners.

Income earned from short-term investments during the Offering 
Period were allocated monthly, 99% to the Limited Partners and 1% 
to the Managing General Partners.

In no event shall the General Partners' interest in profits and 
losses be less than 1%.



4.  Equity Investments
    ------------------

At December 31, 1995 and December 31, 1994, equity investments consisted of:

<TABLE>
<CAPTION>

                                                     December 31, 1995    December 31, 1994
                                        Principal    -----------------    -----------------
                             Investment Amount or     Cost       Fair      Cost        Fair
Industry/Company    Position    Date      Shares      Basis      Value     Basis       Value
- ----------------    --------    ----      ------      -----      -----     -----       -----
<S>                <C>         <C>       <C>       <C>          <C>        <C>         <C>
Biotechnology
- -------------
Acusphere, Inc.    Series B
                   Preferred
                   shares      05/95     125,000   $  200,000    200,000          --          --

CV Therapeutics,   Series D
 Inc.              Preferred
                   shares      03/94     187,500      375,000    375,000     375,000     375,000

CV Therapeutics,   Series E
 Inc.              Preferred
                   shares      09/95      38,400       76,032     76,032          --          --

CV Therapeutics,   Series E
 Inc.              Preferred
                   share warrant
                   at $2.00;
                   expiring
                   09/00       09/95      19,200          768        768          --          --

Prolinx, Inc.      Series A
                   Preferred
                   shares      05/95     119,631      119,631    119,631          --          --

Prolinx, Inc.      Series A
                   Preferred
                   shares      12/95     124,369      124,369    124,369          --          --

Redcell, Inc.      Series B
                   Preferred
                   shares      12/94     132,979      125,000    125,000     125,000     125,000

Diagnostic Equipment
- --------------------
R2 Technology,     Series A-1
 Inc.              Preferred
                   shares      05/94     100,000      100,000    100,000     100,000     100,000

R2 Technology,     Convertible
 Inc.              note (1)    11/95     $33,332       33,759     33,759          --          --

R2 Technology,     Series B
 Inc.              Preferred
                   share 
                   warrant
                   expiring
                   11/00;
                   exercise 
                   price to be
                   determined  11/95       1,667            0          0          --          --

Health Information Systems
- --------------------------
CareCentric        Series A
 Solutions, Inc.   Preferred
                   shares      10/95      66,667      100,000    100,000          --          --

Pharmaceuticals
- ---------------
Arris              Common
 Pharmaceuticals,  shares
 Inc.                          12/95       6,681       88,250     70,652          --          --

Arris              Common
 Pharmaceuticals,  shares held
 Inc.              in escrow   12/95       2,783       36,750     29,430          --          --

Khepri             Series C
 Pharmaceuticals,  Preferred
 Inc.              shares      11/94      83,333           --         --     125,000     125,000

Megabios Corp.     Series C
                   Preferred
                   shares      09/94     193,125      250,000    250,000     250,000     250,000

Megabios Corp.     Series C
                   Preferred
                   shares      12/94      57,938       75,001     75,001      75,001      75,001
  
Megabios Corp.     Series C
                   Preferred
                   shares      07/95      50,212       64,999     64,999          --          --
  
Periodontix,       Series A
 Inc.              Preferred
                   shares      12/93     100,000      100,000    100,000     100,000     100,000

Environmental
- -------------
TMC, Inc.          Series A
                   Preferred
                   shares      12/95      50,000       25,000     25,000          --          --

Venture Capital Limited Partnership Investments
- -----------------------------------------------
Medical Science    Limited
 Partners II       Partnership
                   Interest    various  $200,000      200,000    216,441     125,000     125,000
                                                    ---------  ---------   ---------   ---------

Total Equity Investments                           $2,094,559  2,086,082   1,275,001   1,275,001
                                                    =========  =========   =========   =========

 --   No investment held at end of period.
 0    Investment active with a carrying value or fair value of zero.
(1)   Convertible note includes accrued interest.  Interest rate on such note was 9%.
</TABLE>



<PAGE>

As of December 31, 1995, all equity investments except for Arris 
Pharmaceuticals, Inc. were privately held.

Acusphere, Inc.
- ---------------

In May 1995, the Partnership invested in Acusphere, Inc. by 
purchasing 125,000 Series B Preferred shares at a total cost of 
$200,000.

Arris Pharmaceuticals, Inc./Khepri Pharmaceuticals, Inc.
- --------------------------------------------------------

In December 1995, Khepri Pharmaceuticals, Inc. ("Khepri") was 
acquired by Arris Pharmaceuticals, Inc. ("Arris").  The 
Partnership's Khepri Series C Preferred shares were exchanged for 
9,464 shares of Arris common stock, of which 2,783 were held in 
an escrow account to be released in December 1996.  The 
Partnership recorded a decrease in fair value of $24,918 to 
reflect the publicly-traded market price of its investment at 
December 31, 1995; the investment fair value was adjusted to 
reflect a 25% discount for restricted securities. 

CareCentric Solutions, Inc.
- ---------------------------

In October 1995, the Partnership made an investment in 
CareCentric Solutions, Inc. by purchasing 66,667 Series A 
Preferred shares at a total cost of $100,000.

CV Therapeutics, Inc.
- ---------------------

In September 1995, the Partnership made an additional investment 
in CV Therapeutics, Inc. by purchasing 38,400 Series E Preferred 
shares and receiving a warrant to purchase 19,200 Series E 
Preferred shares for a total cost of $76,800.

Megabios Corp.
- --------------

In July 1995, the Partnership made an additional investment in 
Megabios Corp. by purchasing 50,212 Series C Preferred shares at 
a total cost of $64,999.

Prolinx, Inc.
- -------------

In 1995, the Partnership invested in Prolinx, Inc. by purchasing 
244,000 Series A Preferred shares at a total cost of $244,000.

R2 Technology, Inc.
- -------------------

In November 1995, the Partnership issued a $33,332 convertible 
note to the company and received a warrant to purchase 1,667 
Series B Preferred shares.  The warrant exercise price will be 
determined upon completion of the next round of equity financing.

TMC, Inc.
- ---------

In December 1995, the Partnership made an investment in TMC, Inc. 
by purchasing 50,000 Series A Preferred shares at a total cost of 
$25,000.

Venture Capital Limited Partnership Investments
- -----------------------------------------------

In 1995, the Partnership made additional capital contributions 
totaling $75,000 to Medical Science Partners II.

5.  Cash and Cash Equivalents
    -------------------------

Cash and cash equivalents at December 31, 1995 and 1994 consisted 
of:

<TABLE>
<CAPTION>
                                              1995          1994
                                              ----          ----
<S>                                       <C>           <C>

Demand accounts                           $      606           --
Money-market accounts                      3,948,139    3,571,768
                                           ---------    ---------

  Total                                   $3,948,745    3,571,768
                                           =========    =========
</TABLE>

6.  Distributions Payable
    ---------------------

Distributions payable of $45,924 at December 31, 1994 was paid in 
January 1995.  Pursuant to the Partnership Agreement, income 
earned during the Offering Period on short-term investments are 
to be distributed quarterly.

The Offering Period, as defined by the Partnership Agreement, is 
that period commencing with the effective date of the Prospectus 
when the Partnership began offering Units and ended on May 3, 
1995.  Future distributions will be dependent upon operating 
results.

7.  Commitments
    -----------

The Partnership is a party to financial instruments with off-
balance-sheet risk in the normal course of its business.  
Generally, these instruments are commitments for future equity 
fundings, venture capital limited partnership investments, 
equipment financing commitments, or accounts receivable lines of 
credit that are outstanding but not currently fully utilized.  As 
they do not represent current outstanding balances, these 
unfunded commitments are properly not recognized in the financial 
statements.  At December 31, 1995, the Partnership had unfunded 
commitments of $212,250 related to equity investments and venture 
capital limited partnership investments.

<PAGE>
                              SIGNATURES
                              ----------

Pursuant to the requirements of Section 13 or 15(d) of the 
Securities Exchange Act of 1934, the Registrant has duly caused 
this Report to be signed on its behalf by the undersigned, 
thereunto duly authorized.


                      TECHNOLOGY FUNDING MEDICAL PARTNERS I, L.P.

                           By:  TECHNOLOGY FUNDING INC.
                                Managing General Partner




Date:  March 22, 1996      By:     /s/Debbie A. Wong
                                ------------------------------
                                   Debbie A. Wong
                                   Controller

Pursuant to the requirements of the Securities Exchange Act of 
1934, this Report has been signed below by the following persons 
on behalf of the Registrant and in the capacities and on the 
dates indicated:

          Signature         Capacity                   Date
          ---------         --------                   ----

   /s/Charles R. Kokesh    President, Chief        March 22, 1996
- ------------------------   Executive Officer
Charles R. Kokesh          and Chairman of
                           Technology Funding Inc.
                           and Managing General
                           Partner of Technology
                           Funding Ltd.

   /s/Gregory T. George    Group Vice President    March 22, 1996
- ------------------------   of Technology Funding
Gregory T. George          Inc. and a General
                           Partner of Technology
                           Funding Ltd.


The above represents a majority of the Board of Directors of 
Technology Funding Inc. and a majority of the General Partners of 
Technology Funding Ltd.


<TABLE> <S> <C>

<ARTICLE>6
<LEGEND> THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION 
EXTRACTED FROM THE FORM 10-K AS OF DECEMBER 31, 1995 AND IS 
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL 
STATEMENTS.
<MULTIPLIER>1
       
<FISCAL-YEAR-END>             DEC-31-1995
<PERIOD-START>                JAN-01-1995
<PERIOD-END>                  DEC-31-1995
<PERIOD-TYPE>                        YEAR
<INVESTMENTS-AT-COST>           2,094,559
<INVESTMENTS-AT-VALUE>          2,086,082
<RECEIVABLES>                           0
<ASSETS-OTHER>                     22,874
<OTHER-ITEMS-ASSETS>            3,948,745
<TOTAL-ASSETS>                  6,057,701
<PAYABLE-FOR-SECURITIES>                0
<SENIOR-LONG-TERM-DEBT>                 0
<OTHER-ITEMS-LIABILITIES>          59,601
<TOTAL-LIABILITIES>                59,601
<SENIOR-EQUITY>                         0
<PAID-IN-CAPITAL-COMMON>        6,006,577
<SHARES-COMMON-STOCK>              79,716
<SHARES-COMMON-PRIOR>              60,640
<ACCUMULATED-NII-CURRENT>               0
<OVERDISTRIBUTION-NII>                  0
<ACCUMULATED-NET-GAINS>                 0
<OVERDISTRIBUTION-GAINS>                0
<ACCUM-APPREC-OR-DEPREC>           (8,477)
<NET-ASSETS>                    5,998,100
<DIVIDEND-INCOME>                       0
<INTEREST-INCOME>                 245,800
<OTHER-INCOME>                          0
<EXPENSES-NET>                   (574,299)
<NET-INVESTMENT-INCOME>          (328,499)
<REALIZED-GAINS-CURRENT>                0
<APPREC-INCREASE-CURRENT>          (8,477)
<NET-CHANGE-FROM-OPS>            (336,976)
<EQUALIZATION>                          0
<DISTRIBUTIONS-OF-INCOME>               0
<DISTRIBUTIONS-OF-GAINS>                0
<DISTRIBUTIONS-OTHER>             (77,789)
<NUMBER-OF-SHARES-SOLD>            19,076
<NUMBER-OF-SHARES-REDEEMED>             0
<SHARES-REINVESTED>                     0
<NET-CHANGE-IN-ASSETS>          1,218,614
<ACCUMULATED-NII-PRIOR>                 0
<ACCUMULATED-GAINS-PRIOR>               0
<OVERDISTRIB-NII-PRIOR>                 0
<OVERDIST-NET-GAINS-PRIOR>              0
<GROSS-ADVISORY-FEES>             204,134
<INTEREST-EXPENSE>                      0
<GROSS-EXPENSE>                   652,307
<AVERAGE-NET-ASSETS>            5,388,793
<PER-SHARE-NAV-BEGIN>                  79
<PER-SHARE-NII>                        (4)
<PER-SHARE-GAIN-APPREC>                 0 <F1>
<PER-SHARE-DIVIDEND>                    0
<PER-SHARE-DISTRIBUTIONS>               0
<RETURNS-OF-CAPITAL>                    0
<PER-SHARE-NAV-END>                    75
<EXPENSE-RATIO>                      10.7
<AVG-DEBT-OUTSTANDING>                  0
<AVG-DEBT-PER-SHARE>                    0
<FN>
<F1>
A zero value is used since the change in net unrealized fair 
value is not allocated to General Partners and Limited Partners 
as it is not taxable.  Only taxable gains or losses are allocated 
in accordance with the Partnership Agreement.
</FN>

</TABLE>


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