TECHNOLOGY FUNDING MEDICAL PARTNERS I L P
10-K, 1998-03-27
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<PAGE>
                            UNITED STATES
                   SECURITIES AND EXCHANGE COMMISSION
                         Washington, D.C.  20549

                              FORM 10-K

[X]  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
     SECURITIES EXCHANGE ACT OF 1934

            For The Fiscal Year Ended December 31, 1997

                                    OR

[ ]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
     SECURITIES EXCHANGE ACT OF 1934

            For the transition period from N/A to N/A
                                           ---    ---

                   Commission File No. 814-124

           TECHNOLOGY FUNDING MEDICAL PARTNERS I, L.P.
           -------------------------------------------
         (Exact name of Registrant as specified in its charter)

          DELAWARE                            94-3166762
- -------------------------------    ------------------------------
(State or other jurisdiction of    (I.R.S. Employer  
incorporation or organization)      Identification No.)

2000 Alameda de las Pulgas, Suite 250
San Mateo, California                                       94403
- ---------------------------------------                  --------
(Address of principal executive offices)               (Zip Code)

                          (650) 345-2200
         --------------------------------------------------
        (Registrant's telephone number, including area code)


Securities registered pursuant to Section 12(b) of the Act:  None
Securities registered pursuant to Section 12(g) of the Act:  
Limited Partnership Units

Indicate by check mark whether the Registrant (1) has filed all 
reports required to be filed by Section 13 or 15(d) of the 
Securities Exchange Act of 1934 during the preceding 12 months (or 
for such shorter period that the Registrant was required to file 
such reports), and (2) has been subject to such filing 
requirements for the past 90 days.                    Yes X No
                                                         ---  ---
Indicate by check mark if disclosure of delinquent filers pursuant 
to Item 405 of Regulation S-K is not contained herein, and will 
not be contained, to the best of registrants knowledge, in 
definitive proxy or information statements incorporated by 
reference in Part III of this Form 10-K or any amendment to this 
Form 10-K.                                                  [   ]
No active market for the units of limited partnership interests 
("Units") exists, and therefore the market value of such Units 
cannot be determined.
Documents incorporated by reference:  Portions of the Prospectus 
dated May 3, 1993, forming a part of Registration Statement No. 
33-54002, as modified by Cumulative Supplement No. 4 dated January 
4, 1995, filed pursuant to Rule 424(c) of the General Rules and 
Regulations under the Securities Act of 1933 are incorporated by 
reference in Parts I and III hereof.  Portions of the Prospectus 
of Technology Funding Venture Capital Fund VI, LLC, as revised 
January 22, 1998, forming a part of the December 5, 1997 Pre-
effective Amendment No. 1 to the Form N-2 Registration Statement 
No. 333-23913 dated July 11, 1997, and incorporated by reference 
in part III hereof.

<PAGE>

                                   PART I

Item 1.  BUSINESS
- ------   --------

Technology Funding Medical Partners I, L.P. (the 
"Partnership") is a limited partnership organized under 
the laws of the State of Delaware on September 3, 1992, 
and was inactive until it commenced the sale of Units in 
May of 1993.  The purpose of the Partnership is to make 
venture capital investments in emerging growth companies 
as described in the "Introductory Statement" and 
"Business of the Partnership" sections of the Prospectus 
dated May 3, 1993.  The Partnership has elected to be a 
business development company under the Investment Company 
Act of 1940, as amended (the "Act"), and operates as a 
non-diversified investment company as that term is 
defined in the Act.  Additional characteristics of the 
Partnership's business are discussed in the "Risk 
Factors" and "Conflicts of Interest" sections of the 
Prospectus, which sections are also incorporated herein 
by reference.  The Partnership Agreement provides that 
the Partnership will terminate December 31, 2002, subject 
to the right of the Individual General Partners to extend 
the term for up to two additional two-year periods.

Item 2.  PROPERTIES
- ------   ----------

The Registrant has no material physical properties.

Item 3.  LEGAL PROCEEDINGS
- ------   -----------------

There are no material pending legal proceedings to which 
the Registrant is party or of which any of its property 
is the subject, other than ordinary routine litigation 
incidental to the business of the Partnership.

Item 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS
- ------   ---------------------------------------------------

No matter was submitted to a vote of the holders of 
units of limited partnership interests ("Units") during 
1997.
PART II

Item 5.  MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED 
- ------   -------------------------------------------------
         STOCKHOLDER MATTERS
         -------------------

        (a) There is no established public trading market for the 
            Units.

        (b) At December 31, 1997, there were 833 record holders 
            of Units.

        (c) The Registrant, being a partnership, does not pay 
            dividends. Distributions of cash and securities, 
            however, may be made to the partners in the 
            Partnership pursuant to the Registrant's Partnership 
            Agreement.


Item 6.  SELECTED FINANCIAL DATA
- ------   -----------------------

<TABLE>
<CAPTION>
	For the Years Ended and As of December 31, 
	-------------------------------------------------------
	1997	1996	1995	1994	1993
	-----	-----	-----	-----	-----

<S>                           <C>            <C>          <C>         <C>       

Interest income	$   73,349	178,979	245,800	132,394	16,706
Dividend income	136	--	--	--	--
Net operating loss	(480,820)	(410,597)	(328,499)	(188,769)	(113,431)
Net realized gain (loss) from
 sales of equity investments	1,168	(1,876)	--	--	--
Net realized loss	(479,652)	(412,473)	(328,499)	(188,769)	(113,431)
Change in net unrealized 
 fair value of
 equity investments	1,101,284	377,961	(8,447)	--	--
Net income (loss)	621,632	(34,512)	(336,976)	(188,769)	(113,431)
Net realized loss
  per Unit	(6)	(5)	(4)	(4)	(12)
Total assets	6,646,391	6,019,828	6,057,701	4,876,769	2,597,416
Distributions declared	--	--	77,789	132,394	16,706
Distributions declared
  per Unit (1)	--	--	1	3	2

(1)  Calculation is based on distributions declared to Limited Partners divided by weighted 
average number of Units outstanding during the year.


Refer to the financial statement notes entitled "Summary of Significant Accounting 
Policies" and "Allocation of Profits and Losses" for a description of the method of 
calculation of net realized income (loss) per Unit.
</TABLE>

<PAGE>

Item 7.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL 
- ------   -------------------------------------------------
CONDITION AND RESULTS OF OPERATIONS
- -----------------------------------

Liquidity and Capital Resources
- -------------------------------

During 1997, net cash used by operating activities 
totaled $478,611.  The Partnership paid management fees 
of $145,380 to the Managing General Partners and paid 
related parties $263,204 for operating expenses.  In 
addition, $31,804 was paid to the Individual General 
Partners as compensation for their services.  The 
Partnership paid other operating expenses of $100,938 and 
received $62,715 in interest and dividend income.
During 1997, the Partnership purchased $1,357,786 in 
equity investments mostly in the biotechnology and 
medical/diagnostic equipment industries.  At December 31, 
1997, the Partnership was not committed to fund any 
additional investments.
Cash and cash equivalents at December 31, 1997, were 
$157,137.  Future proceeds from investment sales, 
interest income earned on short-term investments and 
operating cash reserves along with Managing General 
Partners' support are expected to be adequate to fund 
Partnership operations through the next twelve months.
Results of Operations
- ---------------------

1997 compared to 1996
- ---------------------

Net income was $621,632 for 1997 compared to net loss of 
$34,512 in 1996.  The increase to net income was 
primarily due to a $723,323 increase in the change in net 
unrealized fair value of equity investments.  This change 
was partially offset by a $105,630 decrease in interest 
income.

The Partnership recorded an increase in equity investment 
unrealized fair value of $1,101,284 in 1997, compared to 
an increase of $377,961 in 1996.  The 1997 increase was 
primarily attributable to increases in portfolio 
companies in the pharmaceuticals and biotechnology 
industries. 

The Partnership recorded management fees of $158,597 for 
the years ended December 31, 1997 and 1996.  Management 
fees are equal to two percent of total Limited Partner 
capital contributions for the first year of Partnership 
operations through the sixth year.

The Partnership recorded interest income of $73,349 and 
$178,979 for the years ended December 31, 1997 and 1996, 
respectively.  The decrease was mainly due to lower cash 
and cash equivalents balances in 1997 resulting from new 
and follow-on investments.

Total operating expenses were $355,904 and $391,841 for 
1997 and 1996, respectively.  Included in 1997 operating 
expenses are the costs of the Partnership's relocation of 
its administrative and investor service operations to 
Santa Fe, New Mexico.  As disclosed in Note 3 to the 
financial statements, a determination was made in 1996 
that certain operational costs paid directly by the 
Partnership, which had previously been absorbed by the 
General Partners, were not subject to the 3% operational 
expense reimbursement limitation.  Accordingly, $128,120 
was reimbursed by the Partnership to the General 
Partners.

Given the inherent risk associated with the business of 
the Partnership, the future performance of the portfolio 
company investments may significantly impact future 
operations.

1996 compared to 1995
- ---------------------

Net loss was $34,512 for 1996 compared to $336,976 in 
1995.  The decrease in net loss was primarily due to a 
$386,438 increase in change in net unrealized fair value 
of equity investments and a $45,537 decrease in 
management fees.  These changes were partially offset by 
a $66,821 decrease in interest income and a $61,251 
increase in total operating expenses. 

The Partnership recorded an increase in equity investment 
fair value of $377,961 in 1996, compared to a decrease of 
$8,477 in 1995.  The 1996 increase was primarily 
attributable to increases in portfolio companies in the 
pharmaceuticals industry, partially offset by decreases 
in the biotechnology industry.  

The Partnership recorded management fees of $158,597 and 
$204,134 for the years ended December 31, 1996 and 1995, 
respectively.  Management fees are equal to two percent 
of total Limited Partner capital contributions for the 
first year of Partnership operations through the sixth 
year.  Pursuant to the Partnership Agreement, a full 
first year fee is paid to the Managing General Partners 
as each additional Limited Partner is admitted to the 
Partnership, regardless of the date the Limited Partner 
is admitted.  Management fees were higher in 1995 due to 
Unit sales.

The Partnership recorded interest income of $178,979 and 
$245,800 for the years ended December 31, 1996 and 1995, 
respectively.  The decrease was mainly due to lower cash 
and cash equivalents balances in 1996 resulting from new 
and follow-on investments.

Total operating expenses were $391,841 and $330,590 for 
1996 and 1995, respectively.  As disclosed in Note 3 to 
the financial statements, a determination was made in 
1996 that certain operational costs paid directly by the 
Partnership, which had previously been absorbed by the 
General Partners, were not subject to the 3% operational 
expense reimbursement limitation.  Accordingly, $128,120 
was reimbursed by the Partnership.  In 1995, operating 
cost allocations to the Partnership were reevaluated, 
resulting in $52,403 of additional expenses in 1995 of 
which $25,790 related to prior years.  If the $25,790 had 
been recorded in prior years, operating expenses (before 
expenses absorbed by General Partners and expenses 
previously absorbed by General Partners of $128,120) 
would have been $317,731 and $382,758 for 1996 and 1995, 
respectively.  The 1995 amount was higher due to the 
recognition of the $89,086 contingent liability at 
December 31, 1994, which was reflected in 1995 operating 
expenses based on additional Units sold in 1995.

The Year 2000
- -------------

The Managing General Partner is currently reviewing the 
Partnership's information systems in anticipation of the 
potential computer software problems associated with the 
Year 2000.  The Year 2000 issue exists because many 
computer software programs use only two digits to 
identify a year in the date field and were developed 
without considering the impact of the upcoming change in 
the century.  The Managing General Partner currently 
expects to complete the necessary critical software 
conversion modifications in 1999, and does not anticipate 
any material adverse impact on the financial position or 
results of operations of the Partnership, as a result of 
the Year 2000 issue.

Item 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
- ------   -------------------------------------------

The financial statements of the Registrant are set forth 
in Item 14.

Item 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON 
- ------   ------------------------------------------------
ACCOUNTING AND FINANCIAL DISCLOSURE
         -----------------------------------

None



PART III

Item 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT
- -------  --------------------------------------------------

As a partnership, the Registrant has no directors or 
executive officers.  The Management Committee is 
responsible for the management and administration of the 
Partnership.  The members of the Management Committee 
consist of three Individual General Partners and a 
representative from each of Technology Funding Ltd., a 
California limited partnership ("TFL"), and its wholly-
owned subsidiary, Technology Funding Inc., a California 
corporation ("TFI").  TFL and TFI are the Managing 
General Partners.  Information concerning the ownership 
of TFL and the business experience of the key officers of 
TFI and the partners of TFL is incorporated by reference 
from the sections entitled "Management of the Partnership 
- - The Managing General Partners" and "Management of the 
Partnership - Key Personnel of the Managing General 
Partners" in the Prospectus as modified by Cumulative 
Supplement No. 4 dated January 4, 1996, which are 
incorporated herein by reference.  Changes in this 
information that have occurred since the date of the 
Prospectus are included in the Technology Funding Venture 
Capital Fund VI, LLC Prospectus as revised January 22, 
1998, forming a part of the December 5, 1997 Pre-
effective Amendment No 1 to the Form N-2 Registration 
Statement No 333-23913 dated July 11, 1997, which are 
incorporated herein by reference.

Item 11. EXECUTIVE COMPENSATION
- -------  ----------------------

As a partnership, the Registrant has no officers or 
directors.  In 1997, the Partnership incurred $158,597 in 
management fees.  The fees are designed to compensate the 
Managing General Partners for General Partner Overhead 
incurred in performing management duties for the 
Partnership through December 31, 1997.  General Partner 
Overhead (as defined in the Partnership Agreement) 
includes the General Partners' share of rent and 
utilities, and certain salaries and benefits paid by the 
Managing General Partners in performing their obligations 
to the Partnership.  As compensation for their services, 
the Individual General Partners each receive $6,000 
annually beginning on the Commencement Date, plus $1,000 
for each attended meeting of the Individual General 
Partners, and related expenses.  For the year ended 
December 31, 1997, $31,804 of such fees were paid.


Item 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
- -------  ---------------------------------------------------
MANAGEMENT
- ----------

Not applicable.  No Limited Partner beneficially holds 
more than 5% of the aggregate number of Units held by all 
Limited Partners, and neither the General Partners nor 
any of their officers, directors or partners own any 
Units.  The three Individual General Partners each own 20 
Units.  The Individual General Partners control the 
affairs of the Partnership pursuant to the Partnership 
Agreement.

Item 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
- -------  ----------------------------------------------

The Registrant, or its investee companies, have engaged 
in no transactions with the General Partners or their 
officers and partners other than as described above, in 
the notes to the financial statements, or in the 
Partnership Agreement.

<PAGE>

PART IV

Item 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON 
- -------  -------------------------------------------------------
         FORM 8-K
         --------

         (a)  List of Documents filed as part of this Annual 
Report on Form 10-K

             (1)  Financial Statements - the following financial 
statements are filed as a part of this Report:

                  Independent Auditors' Report
                  Balance Sheets as of December 31, 1997
                    and 1996
                  Statements of Operations for the years
                    ended December 31, 1997, 1996 and 1995
                  Statements of Partners' Capital for the years
                    ended December 31, 1997, 1996 and 1995
                  Statements of Cash Flows for the years
                    ended December 31, 1997, 1996 and 1995
                  Notes to Financial Statements

             (2)  Financial Statement Schedules

All schedules have been omitted because they 
are not applicable or the required information 
is included in the financial statements or the 
notes thereto.

             (3)  Exhibits

Registrant's Amended and Restated Limited 
Partnership Agreement (incorporated by 
reference to Exhibit A to Registrant's 
Prospectus dated May 3, 1993, included in 
Registration Statement No. 33-54002 filed 
pursuant to Rule 424(b) of the General Rules 
and Regulations under the Securities Act of 
1933).

         (b)  Reports on Form 8-K

              No reports on Form 8-K were filed by the Registrant 
during the year ended December 31, 1997.

         (c)  Financial Data Schedule for the year ended and as of 
December 31, 1997 (Exhibit 27).

<PAGE>


                   INDEPENDENT AUDITORS' REPORT
                   ----------------------------

The Partners
Technology Funding Medical Partners I, L.P.:


We have audited the accompanying balance sheets of Technology 
Funding Medical Partners I, L.P. (a Delaware limited partnership) 
as of December 31, 1997 and 1996, and the related statements of 
operations, partners' capital, and cash flows for each of the 
years in the three-year period ended December 31, 1997.  These 
financial statements are the responsibility of the Partnership's 
management.  Our responsibility is to express an opinion on these 
financial statements based on our audits.

We conducted our audits in accordance with generally accepted 
auditing standards.  Those standards require that we plan and 
perform the audit to obtain reasonable assurance about whether the 
financial statements are free of material misstatement.  An audit 
includes examining, on a test basis, evidence supporting the 
amounts and disclosures in the financial statements.  Our 
procedures included confirmation of certain securities owned, by 
correspondence with the individual investee companies, and a 
physical examination of those securities held by a safeguarding 
agent as of December 31, 1997 and 1996.  An audit also includes 
assessing the accounting principles used and significant estimates 
made by management, as well as evaluating the overall financial 
statement presentation.  We believe that our audits provide a 
reasonable basis for our opinion.

In our opinion, the financial statements referred to above present 
fairly, in all material respects, the financial position of 
Technology Funding Medical Partners I, L.P. as of December 31, 
1997 and 1996, and the results of its operations and its cash 
flows for each of the years in the three-year period ended 
December 31, 1997, in conformity with generally accepted 
accounting principles.



Albuquerque, New Mexico                 /S/KPMG Peat Marwick LLP
March 25, 1998


<PAGE>

BALANCE SHEETS
- --------------
<TABLE>
<CAPTION>
	December 31,
	--------------------
	1997	1996
	-------	-------
<S>                                         <C>         <C>      
ASSETS

Equity investments (cost basis of
 $5,011,218 and $3,649,974 in 1997
 and 1996, respectively)	$6,481,986	4,019,458

Cash and cash equivalents	157,137	1,985,053

Organizational costs (net of accumulated
 amortization of $34,000 and $26,000 
 in 1997 and 1996, respectively)	6,000	14,000

Other assets	1,268	1,317
	---------	---------

     Total assets	$6,646,391	6,019,828
	=========	=========

LIABILITIES AND PARTNERS' CAPITAL

Accounts payable and accrued expenses	$   29,213	27,548

Due to related parties	31,958	28,692
	---------	---------

     Total liabilities	61,171	56,240

Commitments and subsequent events
 (Notes 3, 5 and 8)

Partners' capital:
  Limited Partners 
   (Units outstanding of 79,716 
    for both 1997 and 1996)	5,127,957	5,602,813
  General Partners	(13,505)	(8,709)
  Net unrealized fair value increase 
   from cost of equity investments	1,470,768	369,484
	---------	---------

     Total partners' capital	6,585,220	5,963,588
	---------	---------

     Total liabilities and partners'
       capital	$6,646,391	6,019,828
	=========	=========
</TABLE>
See accompanying notes to financial statements.

<PAGE

STATEMENTS OF OPERATIONS
- ------------------------
<TABLE>
<CAPTION>
	For the Years Ended December 31,
	------------------------------------
	1997	1996	1995
	-------	------	-------
<S>                          <C>            <C>          <C>      
Income:
  Interest income	$   73,349	178,979	245,800
  Dividend income	136	--	--
	---------	-------	-------
      Total income	73,485	178,979	245,800

Costs and expenses:
  Management fees	158,597	158,597	204,134
  Individual General 
   Partners' compensation	31,804	31,138	31,575
  Amortization of
   organizational costs	8,000	8,000	8,000
  Operating expenses:
    Administrative and 
     investor services	210,039	154,880	252,565
    Investment operations	69,447	62,721	78,333
    Computer services	45,699	38,897	29,172
    Professional fees	30,719	61,233	48,478
    Expenses absorbed by
     General Partners	--	(54,010)	(77,958)
    Expenses previously
     absorbed by General
     Partners	--	128,120	--
	---------	-------	-------
      Total operating
        expenses	355,904	391,841	330,590
	---------	-------	-------
      Total costs and
        expenses	554,305	589,576	574,299
	---------	-------	-------
Net operating loss	(480,820)	(410,597)	(328,499)

Net realized gain (loss) 
  from sales of equity 
  investments	1,168	(1,876)	--
	---------	-------	-------
Net realized loss	(479,652)	(412,473)	(328,499)

Change in net unrealized fair
 value of equity investments	1,101,284	377,961	(8,477)
	---------	-------	-------

Net income (loss)	$  621,632	(34,512)	(336,976)
	=========	=======	=======

Net realized loss per Unit	$       (6)	(5)	(4)
	=========	=======	=======
</TABLE>
See accompanying notes to financial statements.

<PAGE>
STATEMENTS OF PARTNERS' CAPITAL
- -------------------------------
<TABLE>
<CAPTION>
For the years ended December 31, 1997, 1996 and 1995:

                                                          Net Unrealized
                                                        Fair Value (Decrease)
                               Limited      General    Increase from Cost of
                               Partners     Partners    Equity Investments      Total
                               --------     --------    ------------------      -----

<S>                            <C>            <C>           <C>             <C>       

Partners' capital,
 December 31, 1994             $4,780,868     (1,382)            --         4,779,486

Sales of partnership
 interests                      1,865,844      1,868             --         1,867,712

Syndication fees                 (233,326)    (1,007)            --          (234,333)

Distributions of Offering
 Period income                    (77,011)      (778)            --           (77,789)

Change in net unrealized fair
 value of equity investments           --         --         (8,477)           (8,477)

Net realized loss                (325,214)    (3,285)            --          (328,499)
                                ---------     ------      ---------         ---------

Partners' capital,
 December 31, 1995              6,011,161     (4,584)        (8,477)        5,998,100

Change in net unrealized fair
 value of equity investments           --         --        377,961           377,961

Net realized loss                (408,348)    (4,125)            --          (412,473)
                                ---------     ------      ---------         ---------

Partners' capital,
 December 31, 1996              5,602,813     (8,709)       369,484         5,963,588

Change in net unrealized fair
 value of equity investments           --         --      1,101,284         1,101,284

Net realized loss                (474,856)    (4,796)            --          (479,652)
                                ---------     ------      ---------         ---------

Partners' capital,
 December 31, 1997
                               $5,127,957    (13,505)     1,470,768         6,585,220
                                =========     ======      =========         =========

</TABLE>
See accompanying notes to financial statements.

<PAGE>
STATEMENTS OF CASH FLOWS
- ------------------------
<TABLE>
<CAPTION>
	For the Years Ended December 31,
	--------------------------------
	1997	1996	1995
	------	------	------
<S>                                      <C>             <C>          <C>     
Cash flows from operating activities:
  Interest received	$   62,579	160,695	245,373
  Dividends received	136	--	--
  Cash paid to vendors	(100,938)	(111,299)	(92,428)
  Cash paid to related parties	(440,388)	(480,081)	(466,503)
	---------	---------	---------

    Net cash used by operating activities	(478,611)	(430,685)	(313,558)
	---------	---------	---------

Cash flows from investing activities:
  Purchases of equity investments	(1,357,786)	(1,533,007)	(819,131)
  Proceeds from sales of equity
   investments	8,481	--	--
	---------	---------	---------

    Net cash used by investing activities	(1,349,305)	(1,533,007)	(819,131)
	---------	---------	---------

Cash flows from financing activities:
  Proceeds from sales of limited 
    partnership interests	--	--	1,865,844
  General Partners' capital contribution	--	--	1,868
  Distributions of Offering Period income	--	--	(123,713)
  Payments for syndication fees and
    organizational costs	--	--	(234,333)
	---------	---------	---------
    Net cash provided by financing
     activities	--	--	1,509,666
	---------	---------	---------
Net (decrease) increase in cash and 
 cash equivalents	(1,827,916)	(1,963,692)	376,977

Cash and cash equivalents 
 at beginning of year	1,985,053	3,948,745	3,571,768
	---------	---------	---------

Cash and cash equivalents 
 at end of year	$  157,137	1,985,053	3,948,745
	=========	=========	=========
Reconciliation of net income (loss)
 to net cash used by operating 
  activities:

Net income (loss)	$  621,632	 (34,512)	(336,976)

Adjustments to reconcile net income
 (loss) to net cash used by operating
  activities:

   Amortization of organizational costs	8,000	8,000	8,000
   Change in net unrealized fair value
    of equity investments	(1,101,284)	(377,961)	8,477
   Net realized (gain) loss from sales
    of equity investments	(1,168)	1,876	--

Changes in:
   Accounts payable and accrued expenses	1,665	1,433	899
   Due to related parties	3,266	(10,794)	7,343
   Other, net	(10,722)	(18,727)	(1,301)
	---------	---------	---------

Net cash used by operating activities	$ (478,611)	 (430,685)	(313,558)
	=========	=========	=========

</TABLE>
See accompanying notes to financial statements.

<PAGE>

NOTES TO FINANCIAL STATEMENTS
- -----------------------------

1.  Summary of Significant Accounting Policies
    ------------------------------------------

Organization
- ------------

Technology Funding Medical Partners I, L.P. (the "Partnership") is 
a limited partnership organized under the laws of the State of 
Delaware on September 3, 1992.  The purpose of the Partnership is 
to make venture capital investments in emerging growth companies.  
The Partnership elected to be a business development company under 
the Investment Company Act of 1940, as amended (the "Act"), and 
operates as a non-diversified investment company as that term is 
defined in the Act.  The Managing General Partners are Technology 
Funding Ltd. ("TFL"), and Technology Funding Inc. ("TFI"), a 
wholly-owned subsidiary of TFL.  There are also three Individual 
General Partners.  A wholly-owned subsidiary of TFI, Technology 
Funding Securities Corporation ("TFSC"), was the dealer-manager for 
the offering.

For the period from September 3, 1992, through May 3, 1993, the 
Partnership was inactive.  The Partnership's registration statement 
was declared effective by the Securities and Exchange Commission on 
May 3, 1993, and the Partnership began selling units of limited 
partnership interests ("Units") in May of 1993.

On October 8, 1993, the Commencement Date, the minimum number of 
Units required to begin Partnership operations (12,000) had been 
sold.  The offering terminated with 79,716 Units sold on May 3, 
1995.  The Partnership Agreement provides that the Partnership will 
continue until December 31, 2002, unless further extended for up to 
two additional two-year periods from such date if the Individual 
General Partners so determine or unless sooner dissolved.

Preparation of Financial Statements and Use of Estimates
- --------------------------------------------------------

The preparation of financial statements in conformity with 
generally accepted accounting principles requires management to 
make estimates and assumptions that affect the amounts reported in 
the financial statements and accompanying notes. Actual results 
could differ from those estimates.  Estimates are used when 
accounting for investments, change in unrealized fair value of 
investments, liabilities and contingencies.  Because of the 
inherent uncertainty of valuation, the estimated fair value of 
investments may differ significantly from the values that would 
have been used had a ready market for investments existed, and the 
differences could be material.  

Equity Investments
- ------------------

The Partnership's method of accounting for investments, in 
accordance with generally accepted accounting principles, is the 
fair value basis used for investment companies.  The fair value of 
Partnership equity investments is their initial cost basis with 
changes as noted below:

The fair value for publicly-traded equity investments (marketable 
equity securities) is based upon the five-day-average closing sales 
price or bid/ask price that is available on a national securities 
exchange or over-the-counter market.  Certain publicly-traded 
equity investments may not be marketable due to selling 
restrictions and for those securities, an illiquidity discount of 
up to 33% is applied when determining the fair value; the actual 
discount percentage is based on the type and length of the 
restrictions.  Investments valued under this method were $1,180,687 
and $249,469 at December 31, 1997 and 1996, respectively.

All investments which are not publicly traded are valued at fair 
market value as determined by the Managing General Partners in the 
absence of readily ascertainable market values. Investments valued 
under this method were $5,301,299 and $3,769,989 at December 31, 
1997 and 1996, respectively.  Generally, investments in privately 
held companies are valued at original cost unless there is clear 
evidence of a change in fair value, such as a recent round of 
third-party financings or events that, in the opinion of the 
Managing General Partners, indicate a change in value. 

Convertible and subordinated notes receivable are stated at cost 
plus accrued interest, which is equivalent to fair value, and are 
included in equity investments as repayment of these notes 
generally occurs through conversion into equity investments.

Venture capital limited partnership investments are initially 
recorded at cost and are valued based on the fair value of the 
underlying investments.  Limited partnership distributions that are 
a return of capital reduce the cost basis of the Partnership's 
investment.  Distributions from limited partnership cumulative 
earnings are reflected as realized gains by the Partnership.

Where, in the opinion of the Managing General Partners, events 
indicate that the fair value of equity and venture capital 
investments and convertible and subordinated notes receivable may 
not be recoverable, a write down to estimated fair value is 
recorded.  Temporary changes in fair value result in increases or 
decreases to the unrealized fair value of equity investments. 
Adjustments to fair value basis are reflected as "Change in net 
unrealized fair value of equity investments."  In the case of an 
other than temporary decline in value below cost basis, an 
appropriate reduction in the cost basis is recognized as a realized 
loss with the fair value being adjusted to match the new cost 
basis. Cost basis adjustments are reflected as "Realized losses 
from investment write-downs" or "Net realized loss from venture 
capital limited partnership investments" on the Statements of 
Operations. 

Sales of equity investments are recorded on the trade date.  The 
basis on which cost is determined in computing realized gains or 
losses is specific identification.





Cash and Cash Equivalents
- -------------------------

Cash and cash equivalents are principally comprised of cash 
invested in demand accounts and money market instruments and are 
stated at cost plus accrued interest.  The Partnership considers 
all money market and short-term investments with an original 
maturity of three months or less to be cash equivalents.

Organizational Costs
- --------------------

Organizational costs of $40,000 are amortized over 60 months using 
the straight-line method.

Net Realized Income (Loss) Per Unit
- -----------------------------------

Net realized income (loss) per Limited Partner Unit is calculated 
by dividing the weighted average number of Limited Partner Units 
outstanding for the years ended December 31, 1997, 1996 and 1995, 
of 79,716, 79,716 and 74,425, respectively, into total net realized 
loss allocated to the Limited Partners.  The Managing General 
Partners contributed 0.1% of total Limited Partner capital 
contribution and did not receive any Partnership units.

Provision for Income Taxes
- --------------------------

No provision for income taxes has been made by the Partnership as 
the Partnership is not directly subject to taxation.  The partners 
are to report their respective shares of Partnership income or loss 
on their individual tax returns.

The accompanying financial statements are prepared using generally 
accepted accounting principles which may not equate to tax 
accounting.  The difference in the total book and tax cost basis as 
of December 31, 1997, is not material.

Syndication Fees
- ----------------

Syndication fees, which consist of commissions and certain 
organizational and offering costs, are deducted from the partners' 
capital accounts.  Pursuant to the Partnership Agreement, selling 
commissions are allocated solely to the Limited Partners.  All 
other syndication fees are allocated 99% to the Limited Partners 
and 1% to the Managing General Partners.  Syndication fees are not 
deductible for income tax purposes.  Such fees may result in a 
reduction of any gain (or an increase in any loss) realized for tax 
purposes by the partners upon dissolution of the Partnership or a 
transfer of their interests.





2.  Financing of Partnership Operations
    -----------------------------------

The Managing General Partners expect cash received from the future 
liquidation of Partnership investments will provide the necessary 
liquidity to fund Partnership operations.  The Partnership may be 
dependent upon the financial support of the Managing General 
Partners to fund operations if future proceeds are not received 
timely.  The Managing General Partners have committed to support 
the Partnership's working capital requirements through short-term 
advances as necessary.

3.  Related Party Transactions
    --------------------------

Included in costs and expenses are related party costs as follows:
<TABLE>
<CAPTION>
	1997	1996	1995
	------	-----	------
  <S>                                <C>         <C>        <C>

  Management fees	$158,597	158,597	204,134
  Syndication fees	--	--	234,333
  Individual General Partners'
   compensation	31,804	31,138	31,575
  Amortization of organizational
   costs	8,000	8,000	8,000
  Reimbursable operating expenses:
    Administrative and investor 
     services	145,407	114,191	216,113
    Investment operations	63,311	52,354	70,810
    Computer services	44,535	38,897	29,172
    Expenses absorbed by
     General Partners	--	(54,010)	(77,958)
    Expenses previously absorbed
     by General Partners	--	128,120	--
</TABLE>

Management fees are equal to two percent of the total Limited 
Partner capital contributions for the first year of Partnership 
operations through the sixth year.  Beginning in the seventh year, 
management fees will decline by ten percent per year from the 
initial two percent.  Management fees compensate the Managing 
General Partners solely for General Partner overhead (as defined in 
the Partnership Agreement) incurred in supervising the operation 
and management of the Partnership and the Partnership's 
investments.  Pursuant to the Partnership Agreement, a full first 
year fee is paid to the Managing General Partners as each 
additional Limited Partner is admitted to the Partnership, 
regardless of the date the Limited Partner is admitted.  Management 
fees payable were $26,433 and $13,216 at December 31, 1997 and 
1996, respectively.

The Partnership reimbursed the Managing General Partners for 
organizational and offering expenses (up to five percent of the 
total Limited Partner capital contributions) incurred in connection 
with organizing the Partnership and the offering of Units thereof.  
Such reimbursements have been reflected in the Statements of 
Partners' Capital as syndication fees except for $40,000 of 
organizational costs which have been capitalized.

Also included in the syndication fees are commissions and fees paid 
to Technology Funding Securities Corporation (TFSC), the dealer-
manager.  During the year ended December 31, 1995, the Partnership 
paid commissions and fees of $133,618 of which $118,711 was 
reallowed to participating broker-dealers.  In addition, the 
Partnership also paid $7,424 in 1995, to TFSC for due diligence 
expenses (up to one-half of one percent of total Limited Partner 
capital contributions) that TFSC paid to unaffiliated broker-
dealers.  No such commissions and fees were paid in 1997 or 1996.

Pursuant to the Partnership Agreement, the Partnership shall 
reimburse the Managing General Partners for operational costs 
incurred by the Managing General Partners in conjunction with the 
business of the Partnership.  The Partnership may not pay or 
reimburse the Managing General Partners for operational costs that 
aggregate more than 3% of total Limited Partner capital 
contributions of the Partnership in each year through the first 
five years of operations after the termination of Unit sales, and 
1.5% in any year thereafter.  For purposes of this limitation, the 
Partnership's operating year begins on May 3.  No expenses were 
absorbed by the General Partners in 1997.  Amounts due to related 
parties were $5,525 and $15,476 at December 31, 1997 and 1996, 
respectively.  In 1996 and 1995, the Managing General Partners 
absorbed $54,010 and $77,958, respectively, in operating expenses.  
In 1996, it was determined that certain operational costs paid 
directly to the Partnership, which had previously been absorbed by 
the General Partners were not subject to this limitation; 
consequently $128,120 was reimbursed to the General Partners.

Reimbursable operating expenses include expenses (other than 
Organizational and Offering expenses and General Partner overhead) 
such as administrative and investor services, investment 
operations, and computer services.  During late 1995, operating 
cost allocations to the Partnership were reevaluated.  The Managing 
General Partners determined that they had not fully recovered 
allocable overhead as permitted by the Partnership Agreement.  As a 
result, the Partnership was charged additional administrative and 
investor services costs of $52,403 that were not previously 
recognized by the Partnership.  This amount consisted of 
$26,613,and $25,790 for 1995 and prior years, respectively.  If 
this charge had been recorded in prior years, operating expenses 
(before expenses absorbed by General Partners and expenses not 
subject to limitation) would have been $317,731 and $382,758 for 
1996 and 1995, respectively.

As compensation for their services, the Individual General Partners 
each receive $6,000 annually beginning on the Commencement Date, 
plus $1,000 for each of the management committee meetings attended 
and related expenses.  The three Individual General Partners each 
own 20 Units.

Effective November 1, 1997, TFL assigned its California office 
lease to Technology Funding Property Management LLC (TFPM), an 
entity that is affiliated to the Managing General Partner.  Under 
the terms of a rent agreement, TFPM charges the Partnership for its 
share of office rent and related overhead costs.  These amounts are 
included in administrative and investor service costs.
Under the terms of a computer service agreement, Technology 
Administrative Management, a division of TFL, charges the 
Partnership for its share of computer support costs.  These amounts 
are included in computer services expenses.

Officers of the Managing General Partners occasionally receive 
stock options as compensation for serving on the Boards of 
Directors of portfolio companies.  It is the Managing General 
Partners' policy that all such compensation be transferred to the 
investing partnerships.  If the options are non-transferable, they 
are not recorded as an asset of the Partnership.  Any profit from 
the exercise of such options will be transferred if and when the 
options are exercised and the underlying stock is sold by the 
officers.

4.  Allocation of Profits and Losses
    --------------------------------

Net realized profit and loss of the Partnership are allocated based 
on the beginning of year partners' capital balances as follows:

(a)   Profits:

 (i) first, to those partners with deficit capital account 
balances in proportion to such deficits until the 
deficits have been eliminated; then

(ii) second, to the partners as necessary to offset net loss 
and sales commissions previously allocated to such 
partners; then

(iii)third, 75% to the Limited Partners as a group in 
proportion to the number of Units, 5% to the Limited 
Partners in proportion to the Unit months of each 
Limited Partner, and 20% to the Managing General 
Partners.  Unit months are the number of half months a 
Unit would be outstanding if held from the date the 
original holder of such Unit was deemed admitted into 
the Partnership until the termination of the offering 
of Units.

(b)   Losses:

(i)  first, to the partners as necessary to offset net 
profit previously allocated to the partners under 
(a)(iii) above plus losses from unaffiliated venture 
capital limited partnership investments; then

(ii) 99% to the Limited Partners as a group and 1% to the 
Managing General Partners.

Losses allocable to Limited Partners in excess of their capital 
account balances will be allocated to the Managing General 
Partners.  Net profit thereafter, otherwise allocable to those 
Limited Partners, would be allocated to the Managing General 
Partners to the extent of such losses.  

As indicated above, losses from unaffiliated venture capital 
limited partnership investments are allocated pursuant to section 
(b).  Gains are allocated first to offset previously allocated 
losses pursuant to (b)(i) above, and then 99% to Limited Partners 
and 1% to the Managing General Partners.

Income earned from short-term investments during the Offering 
Period was allocated monthly, 99% to the Limited Partners and 1% to 
the Managing General Partners.

In no event shall the General Partners' interest in profits and 
losses be less than 1%.



5.  Equity Investments
    ------------------

At December 31, 1997, and December 31, 1996, equity investments consisted of:

<TABLE>
<CAPTION>
December 31, 1997     December 31, 1996
                                        Principal     ------------------     -----------------
                             Investment Amount or     Cost       Fair        Cost        Fair
Industry/Company    Position    Date      Shares      Basis      Value       Basis       Value
- ----------------    --------    ----      ------      -----      -----       -----       -----
<S>                <C>         <C>      <C>        <C>         <C>         <C>         <C>

Medical/Biotechnology
- ---------------------
Acusphere, Inc.    Series B
                   Preferred
                   shares      05/95     125,000   $  200,000    375,000     200,000     267,500
Acusphere, Inc.    Series C
                   Preferred
                   shares      05/96     163,552      350,001    490,656     350,001     350,001
Acusphere, Inc.    Series D
                   Preferred
                   shares      11/97      52,083      156,250    156,250          --          --
Biex, Inc.         Series E
                   Preferred
                   shares       8/97     120,000      300,000    300,000          --          --
CV Therapeutics,   Common
 Inc.              share
                   warrant at
                   $20.00;
                   expiring
                   09/00       09/95       1,920          768          0         768           0
CV Therapeutics,   Common
 Inc.              shares      11/96      26,455      487,224    240,211     487,224     125,982
Peptide            Common
 Therapeutics      shares
 Group                         02/96       2,151           --         --       7,313       7,823
Prolinx, Inc.      Series A
                   Preferred
                   shares      05/95     119,631      119,631    209,354     119,631     119,631
Prolinx, Inc.      Series A
                   Preferred
                   shares      12/95     124,369      124,369    217,646     124,369     124,369
Prolinx, Inc.      Series A
                   Preferred
                   shares      09/96     156,000      156,000    273,000     156,000     156,000
Prolinx, Inc.      Series B
                   Preferred
                   shares      07/97     164,835      288,461    288,461          --          --
RedCell, Inc.      Series B
                   Preferred
                   shares      12/94     132,979      125,000          0     125,000     125,000
RedCell, Inc.      Convertible
                   note (1)    02/96     $89,966       98,149     98,149      96,285      96,285
RedCell, Inc.      Series C
                   Preferred
                   share warrant
                   exercise
                   price to be           $13,495
                   determined;           aggregate
                   expiring              purchase
                   02/01       02/96     price              0          0           0           0
RedCell, Inc.      Convertible
                   note (1)    07/96     $71,973       76,131     76,131      74,692      74,692
RedCell, Inc.      Series C
                   Preferred
                   share warrant
                   exercise 
                   price to be           $10,796
                   determined;           aggregate
                   expiring              purchase
                   07/01       07/96     price              0          0           0           0

Medical/Diagnostic Equipment
- ----------------------------
Endocare, Inc.     Common
                   shares      08/96       2,000        6,000      7,160       6,000       4,824





Endocare, Inc.     Common 
                   share
                   warrant at
                   $3.00;
                   expiring
                   08/01       08/96      30,000            0     13,050           0      12,060
Endocare, Inc.     Convertible
                   note (1)    08/96    $150,000           --         --     158,533     158,533
Endocare, Inc.     Common 
                   shares      01/97      66,400      166,000    214,480          --          --
Endocare, Inc.     Common 
                   shares      01/97      84,000      294,000    300,720          --          --
LifeCell           Series B
 Corporation       Preferred
                   shares      11/96       2,500      232,089    232,089     247,500     247,500
LifeCell           Common 
 Corporation       share
                   warrant at
                   $4.13;
                   expiring
                   11/01       11/96      56,451        2,500     37,258       2,500       2,500
LifeCell           Series B
 Corporation       Preferred
                   shares      02/97          29        2,692      2,692          --          --
LifeCell           Series B
 Corporation       Preferred
                   shares      05/97          60        5,570      5,570          --          --
LifeCell           Series B
 Corporation       Preferred
                   shares      08/97          38        3,528      3,528          --          --
LifeCell           Series B
 Corporation       Preferred
                   shares      11/97          39        3,621      3,621          --          --
R2 Technology,     Series A-1
 Inc.              Preferred
                   shares      05/94     100,000      100,000    184,000     100,000     184,000
R2 Technology,     Series B
 Inc.              Preferred
                   share warrant
                   at $2.00;
                   expiring
                   11/00       11/95       2,417            0          0           0           0
R2 Technology,     Series B-1
 Inc.              Preferred
                   shares      03/96      17,134       34,268     34,268      34,268      34,268

Health Information Systems
- --------------------------
ADESSO Specialty   Series D
 Services          Preferred
 Organization,     shares
 Inc.                          12/97      11,905      100,002    100,002          --          --
CareCentric        Series A
 Solutions, Inc.   Preferred
                   shares      10/95      66,667      100,000     65,710     100,000     113,333
CareCentric        Series B
 Solutions, Inc.   Preferred
                   shares      09/96      86,999      130,499     85,749     130,499     130,499
CareCentric        Series C
 Solutions, Inc.   Preferred
                   shares      12/97      31,051       32,604     32,604          --          --
CareCentric        Common
 Solutions, Inc.   share
                   warrant at
                   $.15
                   expiring
                   12/02       12/97      15,525       13,972     13,972          --          --

Pharmaceuticals
- ---------------
Axys               Common
 Pharmaceuticals   shares
 Inc.                          12/95       9,464      125,000     78,930     125,000     130,017
Megabios Corp.     Common
	shares      09/94      64,375      250,000    725,957     250,000     482,813
Megabios Corp.     Common
	shares      12/94      19,312       75,001    217,781      75,001     144,845
Megabios Corp.     Common
	shares      07/95      16,737       64,999    188,743      64,999     125,530
Neurex             Common
 Corporation       shares      09/96         149        3,129      2,004       3,129       2,350
Periodontix,       Series A
 Inc.              Preferred
                   shares      12/93     100,000      100,000    245,000     100,000     200,000
Periodontix,       Series B
 Inc.              Preferred
                   shares      02/96      67,000      134,000    164,150     134,000     134,000

Environmental
- -------------
Naiad Technologies,Series A
 Inc.              Preferred
                   shares      12/95      50,000       25,000    162,500      25,000     100,000
Naiad Technologies,Series B
 Inc.              Preferred 
                   Shares      11/96      62,602      125,204    203,457     125,204     125,204
Naiad Technologies,Series C
 Inc.              Preferred 
                   Shares      11/97      49,230      159,998    159,998          --          --

Venture Capital Limited Partnership Investments
- -----------------------------------------------
Medical Science    Limited
 Partners II       Partnership
                   Interests   various  $250,000      239,558    272,135     227,058     239,899
                                                    ---------  ---------   ---------   ---------

Total Equity Investments                           $5,011,218  6,481,986   3,649,974   4,019,458
                                                    =========  =========   =========   =========

 --   No investment held at end of period.
 0    Investment active with a carrying value or fair value of zero.
(1)    Convertible notes include accrued interest.  Interest rates on such notes ranged from 8%  
      to 16%.


</TABLE>

Marketable Equity Securities
- ----------------------------

At December 31, 1997 and 1996, marketable equity securities had 
an aggregate cost of $1,084,621 and $587,242, respectively, and 
an aggregate fair value of $1,180,687 and $249,469, respectively.  
The unrealized gain/loss at December 31, 1997 and 1996, included 
gross gains of $391,042 and $5,527, respectively. 

Acusphere, Inc.
- ---------------

In November of 1997, the Partnership made an additional 
investment in the company by purchasing 52,083 Series D Preferred 
shares for $156,250.  The pricing of this round, in which third 
parties participated, indicated a fair value increase of $248,155 
for the Partnership's existing investment.

Adesso Specialty Services Organization, Inc.
- ---------------------------------------------

In December of 1997, the Partnership purchased 11,905 Series D 
Preferred shares for $100,002.

Biex, Inc.
- ----------

In August of 1997, the Partnership purchased 120,000 Series E 
Preferred shares for $300,000.

CareCentric Solutions, Inc.
- ---------------------------

In December of 1997, the Partnership made an additional 
investment in the company by purchasing 31,051 Series C Preferred 
shares and a warrant for 15,525 common shares for a total cost of 
$46,576.  The pricing of this round, in which third parties 
participated, indicated a decrease in fair value of $92,373 for 
the Partnership's existing investment.

Endocare, Inc.
- --------------

In January of 1997, the Partnership made an additional investment 
in the company by purchasing 84,000 common shares for $294,000.  
In addition, the Partnership converted its $150,000 note 
receivable, including accrued interest of $16,000, into 66,400 
common shares at a total cost of $166,000.  At December 31, 1997, 
the Partnership recorded an increase of $58,526 in fair value to 
reflect the publicly-traded market price of its common stock and 
warrant investments; the fair value was net of a discount applied 
for restricted securities.

Megabios Corp.
- --------------

In September of 1997, the company completed its initial public 
offering ("IPO").  Prior to the IPO, the company effected a 
reverse stock split resulting in the Partnership's Preferred 
shares being converted to 100,424 Common shares.  At December 31, 
1997, the Partnership recorded an increase in the change in fair 
value of $379,293 to reflect the publicly traded market price of 
its investment, net of a discount applied as the Partnership is 
restricted from selling its shares until March 1998.

Subsequent to year end, the fair value of the Partnership's 
investment decreased by $319,047 as a result of a decrease in the 
publicly-traded market price at March 23, 1998.

Naiad Technologies, Inc. (formerly TMC, Inc.)
- ---------------------------------------------

In November of 1997, the Partnership made an additional 
investment in the company by purchasing 49,230 Series C Preferred 
shares for $159,998.  The pricing of this round, in which third 
parties participated, indicated an increase in fair value of 
$140,753 for the Partnership's existing investment.

Periodontix, Inc.
- -----------------

In December of 1997, the company had an additional round of 
financing in which the Partnership did not participate.  The 
pricing of this round, indicated an increase in fair value of 
$75,150 for the Partnership's existing investment.

Prolinx, Inc.
- -------------

In July of 1997, the Partnership made an additional investment in 
the company by purchasing 164,835 Series B Preferred shares for 
$288,461.  The pricing of this round in which third parties 
participated, indicated a $300,000 increase in the fair value of 
the Partnership's existing investment.

RedCell, Inc.
- -------------

During the second quarter of 1997, the company had a new round of 
financing in which the Partnership did not participate.  The 
pricing of this round indicated a decrease in fair value of 
$125,000 for the Partnership's existing investment at December 
31, 1997.

Venture Capital Limited Partnership Investment
- ----------------------------------------------

The Partnership recorded a cost basis increase of $12,500 in 
venture capital limited partnership investments in 1997, as a 
result of an additional capital contribution.  The Partnership 
recorded an increase in fair value of $19,736 due to the 
additional contribution and an increase in fair value of the 
underlying investments. 





Other Equity Investments
- ------------------------

Other significant changes reflected above relate to market value 
fluctuations or the elimination of a discount relating to selling 
restrictions for publicly-traded portfolio companies.

6.  Change in Net Unrealized Fair Value of Equity Investments
    ---------------------------------------------------------

In accordance with the accounting policy as stated in Note 1, the 
Statements of Operations include a line item entitled "Change in 
net unrealized fair value of equity investments. "  The table 
below discloses details of the changes:

<TABLE>
<CAPTION>

	For the Years Ended December 31,
	------------------------------------

	1997	1996	1995
	--------	--------	--------
<S>                          <C>             <C>           <C>   

Increase (decrease) in 
 fair value from cost of
 marketable equity
 securities	$  96,066	(337,773)	--

Increase (decrease) in fair 
 value from cost of
 non-marketable 
 equity securities	1,374,702	707,257	(8,477)
	---------	-------	-----

 Net unrealized fair 
  value increase (decrease)
  from cost at end of year	1,470,768	369,484	(8,477)

 Net unrealized fair
  value increase (decrease)
  from cost at beginning 
  of year	369,484	(8,477)	--
	---------	-------	-----

Change in net unrealized
 fair value of equity
 investments	$1,101,284	377,961	(8,477)
	=========	=======	=====

</TABLE>

7.  Cash and Cash Equivalents
    -------------------------

Cash and cash equivalents at December 31, 1997 and 1996,
consisted of:

<TABLE>
<CAPTION>
	1997	1996
	-------	-------

<S>                                       <C>           <C>

Demand accounts	$  3,470	2,844
Money-market accounts	153,667	1,982,209
	-------	---------

  Total	$157,137	1,985,053
	=======	=========

</TABLE>

8.  Commitments
    -----------

The Partnership is a party to financial instruments with off-
balance-sheet risk in the normal course of its business.  
Generally, these instruments are commitments for future equity 
fundings, venture capital limited partnership investments, 
equipment financing commitments, or accounts receivable lines of 
credit that are outstanding but not currently fully utilized.  As 
they do not represent current outstanding balances, these 
unfunded commitments are properly not recognized in the financial 
statements.  At December 31, 1997, the Partnership had no 
unfunded commitments.

The Partnership uses the same credit policies in making these 
commitments and conditional obligations as it does for on-
balance-sheet instruments.  Commitments to extend financing are 
agreements to lend to a company as long as there are no 
violations of any conditions established in the contract.  The 
credit lines generally have fixed termination dates or other 
termination clauses.  Since many of the commitments are expected 
to expire without being fully drawn upon, the total commitment 
amounts do not necessarily represent future cash requirements. 

<PAGE>


                              SIGNATURES
                              ----------

Pursuant to the requirements of Section 13 or 15(d) of the 
Securities Exchange Act of 1934, the Registrant has duly caused 
this Report to be signed on its behalf by the undersigned, 
thereunto duly authorized.


                      TECHNOLOGY FUNDING MEDICAL PARTNERS I, L.P.

                           By:  TECHNOLOGY FUNDING INC.
                                Managing General Partner


Date:  March 25, 1998      By:     /s/Michael Brenner
                                ------------------------------
                                   Michael Brenner
Controller

Pursuant to the requirements of the Securities Exchange Act of 
1934, this Report has been signed below by the following persons 
on behalf of the Registrant and in the capacities and on the 
dates indicated:

          Signature         Capacity                   Date
          ---------         --------                   ----

   /s/Charles R. Kokesh    President, Chief        March 25, 1998
- ------------------------   Executive Officer,
Charles R. Kokesh          Chief Financial 
                           Officer and Chairman of
                           Technology Funding Inc.
                           and Managing General
                           Partner of Technology
                           Funding, Ltd.

   /s/Gregory T. George    Group Vice President    March 25, 1998
- ------------------------   of Technology Funding
Gregory T. George          Inc. and a General
                           Partner of Technology
                           Funding, Ltd.

The above represents the Board of Directors of Technology Funding 
Inc. and the General Partners of Technology Funding Ltd.




<TABLE> <S> <C>

<ARTICLE>6
<LEGEND> THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION 
EXTRACTED FROM THE FORM 10-K AS OF DECEMBER 31, 1997, AND IS 
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL 
STATEMENTS.
<MULTIPLIER>1
       
<FISCAL-YEAR-END>             DEC-31-1997
<PERIOD-START>                JAN-01-1997
<PERIOD-END>                  DEC-31-1997
<PERIOD-TYPE>                        YEAR
<INVESTMENTS-AT-COST>           5,011,218
<INVESTMENTS-AT-VALUE>          6,481,986
<RECEIVABLES>                           0
<ASSETS-OTHER>                      7,268
<OTHER-ITEMS-ASSETS>              157,137
<TOTAL-ASSETS>                  6,646,391
<PAYABLE-FOR-SECURITIES>                0
<SENIOR-LONG-TERM-DEBT>                 0
<OTHER-ITEMS-LIABILITIES>          61,171
<TOTAL-LIABILITIES>                61,171
<SENIOR-EQUITY>                         0
<PAID-IN-CAPITAL-COMMON>        5,114,452
<SHARES-COMMON-STOCK>              79,716
<SHARES-COMMON-PRIOR>              79,716
<ACCUMULATED-NII-CURRENT>               0
<OVERDISTRIBUTION-NII>                  0
<ACCUMULATED-NET-GAINS>                 0
<OVERDISTRIBUTION-GAINS>                0
<ACCUM-APPREC-OR-DEPREC>        1,470,768
<NET-ASSETS>                    6,585,220
<DIVIDEND-INCOME>                       0
<INTEREST-INCOME>                  73,349
<OTHER-INCOME>                        136
<EXPENSES-NET>                    554,305
<NET-INVESTMENT-INCOME>          (480,820)
<REALIZED-GAINS-CURRENT>            1,168
<APPREC-INCREASE-CURRENT>       1,101,284
<NET-CHANGE-FROM-OPS>             621,632
<EQUALIZATION>                          0
<DISTRIBUTIONS-OF-INCOME>               0
<DISTRIBUTIONS-OF-GAINS>                0
<DISTRIBUTIONS-OTHER>                   0
<NUMBER-OF-SHARES-SOLD>                 0
<NUMBER-OF-SHARES-REDEEMED>             0
<SHARES-REINVESTED>                     0
<NET-CHANGE-IN-ASSETS>            621,632
<ACCUMULATED-NII-PRIOR>                 0
<ACCUMULATED-GAINS-PRIOR>               0
<OVERDISTRIB-NII-PRIOR>                 0
<OVERDIST-NET-GAINS-PRIOR>              0
<GROSS-ADVISORY-FEES>             158,597
<INTEREST-EXPENSE>                      0
<GROSS-EXPENSE>                   554,625
<AVERAGE-NET-ASSETS>            6,274,404
<PER-SHARE-NAV-BEGIN>                  75
<PER-SHARE-NII>                        (6)
<PER-SHARE-GAIN-APPREC>                 0 <F1>
<PER-SHARE-DIVIDEND>                    0
<PER-SHARE-DISTRIBUTIONS>               0
<RETURNS-OF-CAPITAL>                    0
<PER-SHARE-NAV-END>                    70
<EXPENSE-RATIO>                       8.8
<AVG-DEBT-OUTSTANDING>                  0
<AVG-DEBT-PER-SHARE>                    0
<FN>
<F1>
A zero value is used since the change in net unrealized fair 
value is not allocated to General Partners and Limited Partners 
as it is not taxable.  Only taxable gains or losses are allocated 
in accordance with the Partnership Agreement.
</FN>

</TABLE>


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