PROFESSIONAL ADVISORY SERVICES INC
13F-HR, 2001-01-04
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				UNITED STATES
					SECURITIES AND EXCHANGE COMMISSION
					Washington, DC  20549
					FORM 13F
  					FORM 13F Cover Page

Report for the Calendar Year or Quarter Ended:	December 31, 2000

Check here if Amendment  [    ];     Amendment Number:
This Amendment  (check only one): 	[    ]  is a restatement
					[    ]  adds new holdings entries

Institutional Investment Manager Filing this Report:
Name:			Professional Advisory Services, Inc.
Address:		2770 Indian River Blvd. - Suite 204
			Vero Beach, FL  32960

13F File Number:  28-3358

The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing this report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables are considered integral parts of this form.

Person signing the report on behalf of Reporting Manager:
Name:	Kenneth M. Ligon
Title:	Secretary/Treasurer
Phone:	561-778-0552
Signature, Place and Date of Signing: ________________________

	Kenneth M. Ligon	Vero Beach, FL		January 4, 2001

Report type  (check one only):
	[ x  ]	13F Holdings Report
	[    ]	13F Notice Filing
	[    ]	13F Combination Report
List of other managers reporting for this Manager:		NONE

I am signing this report as required by the Securities Exchange Act of 1934.



                       FORM 13F SUMMARY PAGE

Report Summary:

Number of Other Included Managers:		0

Form 13F Information Table Entry Total:	44

Form 13F Information Table Value Total:	$295,495

List of Other Managers Included:		NONE
<TABLE>                                 <C>                          <C>
   ITEM 1:                      ITEM 2: ITEM 3:    ITEM 4:  ITEM 5:   ITEM 6(a):ITEM 8(a):
   NAME OF ISSUER   	        COM     CUSIP      MKT VAL  SHARES PR  	   SOLE      SOLE
D  ABBOTT LABS                  COM     002824100      569      11750     11750     11750
D  AES CORP                     COM     00130H105     7694     138950    138950    138950
D  AMERICAN EXPRESS CO          COM     025816109     9962     181340    181340    181340
D  AMERICAN INTERNATIONAL GP    COM     026874107    12520     127021    127021    127021
D  AUTOMATIC DATA PROCESSING    COM     053015103    10789     170400    170400    170400
D  AVAYA, INC.                  COM     053499109      258      25057     25057     25057
D  BANCO SANTANDER CENT HISP    COM     05964H105     9240     874785    874785    874785
D  BELLSOUTH CORP               COM     079860102      502      12268     12268     12268
D  BRISTOL MYERS SQUIBB CO.     COM     110122108      844      11417     11417     11417
D  CISCO SYSTEMS                COM     17275R102    12460     325739    325739    325739
D  CITIGROUP, INC.              COM     172967101    14784     289516    289516    289516
D  COCA COLA                    COM     191216100     8213     134770    134770    134770
D  COMPAQ COMPUTER              COM     204493100      311      20670     20670     20670
D  DISNEY, WALT                 COM     254687106     9830     339685    339685    339685
D  DONALDSON COMPANY            COM     257651109     1411      50725     50725     50725
D  DUKE POWER                   COM     264399106     2367      27760     27760     27760
D  DUPONT DE NEMOURS, I.E.      COM     263534109     8763     181384    181384    181384
D  E M C CORP                   COM     268648102     3864      58100     58100     58100
D  ERICSSON LM TEL - ADR        COM     294821400     8441     754480    754480    754480
D  EXXON MOBIL CORP             COM     30231G102    12301     141491    141491    141491
D  GANNETT CO.                  COM     364730101     1301      20625     20625     20625
D  GENERAL ELECTRIC             COM     369604103    13442     280406    280406    280406
D  GOLDMAN SACHS                COM     38141G104     7880      73690     73690     73690
D  HARBOR FLORIDA BANCSHARES    COM     411901101      211      14100     14100     14100
D  INTEL                        COM     458140100     9701     322689    322689    322689
D  JOHNSON & JOHNSON            COM     478160104    11048     105157    105157    105157
D  LUCENT TECHNOLOGIES          COM     549463107     4014     297297    297297    297297
D  MEDTRONIC INC                COM     585055106     1794      29722     29722     29722
D  MERCK & CO.                  COM     589331107    14209     151764    151764    151764
D  MICROSOFT                    COM     594918104     8829     203541    203541    203541
D  NORFOLK SOUTHERN CORP        COM     655844108     5050     379320    379320    379320
D  NORTEL NETWORK               COM     656568102     4899     152790    152790    152790
D  ORACLE CORP                  COM     68389X105     9922     341390    341390    341390
D  PEPSICO                      COM     713448108     9146     184525    184525    184525
D  PFIZER INC                   COM     717081103    11133     242029    242029    242029
D  PROCTOR & GAMBLE             COM     742718109     9104     116065    116065    116065
D  ROYAL DUTCH PETROL.          COM     780257804      963      15900     15900     15900
D  SCHERING PLOUGH CORP         COM     806605101      756      13320     13320     13320
D  STATE STREET CORP            COM     857477103    11925      96010     96010     96010
D  TEXAS INSTRUMENTS            COM     882508104    10175     214785    214785    214785
D  TYCO INTL                    COM     902124106     4842      87250     87250     87250
D  UNISOURCE ENERGY CORP        COM     909205106      589      31300     31300     31300
D  VIACOM CL B                  COM     925524308     8691     185902    185902    185902
D  WAL-MART                     COM     931142103      748      14084     14084     14084

S  REPORT SUMMARY                     44RECORDS     295495                    0OTHER MGRS
</TABLE>



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