<PAGE> 1
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13D
(Amendment No. 1)*
Under the Securities Exchange Act of 1934
XENOVA GROUP PLC
----------------
(Name of Issuer)
ORDINARY SHARES OF 10p EACH
---------------------------
(Title of Class of Securities)
984111104
---------
(CUSIP Number)
DR. ANDREAS BREMER
GRAFENAUWEG 4, 6301 ZUG CH/SWITZERLAND
011-41-41-724-5959
------------------
(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
Copy to:
Daniel L. Goelzer, Esq.
Baker & McKenzie
815 Connecticut Avenue, N.W.
Washington, D.C. 20006
MARCH 11, 1997
--------------
(Date of Event which Requires
Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G
to report the acquisition which is the subject of this Schedule 13D, and is
filing this schedule because of Rule 13d- 1(b)(3) or (4), check the following
box [ ].
Check the following box if a fee is being paid with the statement [ ].
(A fee is not required only if the reporting person: (1) has a previous
statement on file reporting beneficial ownership of more than five percent of
the class of securities described in Item 1; and (2) has filed no amendment
subsequent thereto reporting beneficial ownership of five percent or less of
such class.) (See Rule 13d-7.)
Note: Six copies of this statement, including all exhibits, should be
filed with the Commission. See Rule 13d-1(a) for other parties to whom copies
are to be sent.
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.
Page 1 of 5 Pages
<PAGE> 2
The information required on the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that
section of the Act but shall be subject to all other provisions of the Act
(however, see the Notes).
Page 2 of 5 Pages
<PAGE> 3
CUSIP No. 984111104
- -------------------------------------------------------------------------------
(1) Name of Reporting Person
S.S. or I.R.S. Identification No. of Above Person
BB Biotech AG
Biotech Target, S.A.
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(2) Check the Appropriate Box if a Member (a) [ ]
of a Group (See Instructions) (b) [X]
- -------------------------------------------------------------------------------
(3) SEC Use Only
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(4) Source of Funds (See Instructions)
WC
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(5) Check Box if Disclosure of Legal Proceedings [ ]
is Required Pursuant to Item 2(d) or 2(e)
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(6) Citizenship or Place of Organization
BB Biotech AG -- Switzerland
Biotech Target, S.A. -- Panama
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Number of Shares (7) Sole Voting Power:
Beneficially Owned 0 by BB Biotech AG
by Each Reporting ---------------------------------
Person With (8) Shared Voting Power
100,000 (See Item 5)
---------------------------------
(9) Sole Dispositive Power
0 by BB Biotech AG
---------------------------------
(10) Shared Dispositive Power
100,000(See Item 5)
---------------------------------
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(11) Aggregate Amount Beneficially Owned by Each Reporting Person
100,000 shares (See Item 5)
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(12) Check Box if the Aggregate Amount in Row (11) [ ]
Excludes Certain Shares (See Instructions)
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(13) Percent of Class Represented by Amount in Row (11)
0.79%
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(14) Type of Reporting Person (See Instructions)
BB Biotech AG -- HC, CO
Biotech Target, S.A. -- CO
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Page 3 of 5 Pages
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SCHEDULE 13D
This Amendment No. 1 reflects open market sales of 1,150,000 ordinary
shares, 10p each ("Ordinary Shares"), of Xenova Group PLC ("Xenova") by Biotech
Target S.A., a Panamanian corporation ("Biotech Target") and wholly owned
subsidiary of BB Biotech AG, a Swiss corporation ("BB Biotech") during the
period of March 6, 1997 through April 15, 1997. As of March 19, 1997, Biotech
Target and BB Biotech ceased to have beneficial ownership of more than 5
percent of the outstanding ordinary shares of Xenova.
ITEM 5. INTEREST IN SECURITIES OF THE ISSUER
ITEMS 5(a), (b), (c) AND (e) ARE AMENDED IN THEIR ENTIRETY TO READ AS
FOLLOWS:
(a) As of October 26, 1995, Biotech Target held 1,000,000 shares,
or approximately 8.8 percent, of Xenova's outstanding ordinary shares. Since
that time, Biotech Target has sold shares in the open market to reduce its
holdings to 100,000 shares, or approximately 0.79 percent of the outstanding
ordinary shares of Xenova, as reported in Xenova's Form 20-F for the period
ending December 31, 1995. As a result of its ownership of Biotech Target, BB
Biotech may be deemed to be the indirect beneficial owner of the Xenova
ordinary shares held directly in the aggregate by Biotech Target as of April
11, 1997, which represents approximately 0.79 percent of the outstanding Xenova
ordinary shares. No Xenova ordinary shares are directly owned by BB Biotech. To
the best knowledge of BB Biotech and Biotech Target, no director or executive
officer of BB Biotech or Biotech Target owns any Xenova ordinary shares.
(b) The number of ordinary shares of Xenova to which there is
sole power to vote or to direct the vote, shared power to vote or to direct the
vote, sole power to dispose or to direct the disposition, or shared power to
dispose or direct the disposition is set forth in the cover pages and such
information is incorporated herein by reference. BB Biotech, through its
ownership of Biotech Target, may be deemed to beneficially own the ordinary
shares of Xenova within the meaning of Regulation 13D under the Exchange Act,
and may be deemed to share with Biotech Target the power to vote or direct the
vote of and the power to dispose of or direct the disposition of the aggregate
100,000 ordinary shares of Xenova directly held by Biotech Target. BB Biotech
hereby expressly declares that the filing of this statement shall not be
construed as an admission that it is, for purposes of Section 13(d) of the
Exchange Act, the beneficial owner of the Xenova ordinary shares held by
Biotech Target.
(c) A summary of transactions in Xenova ordinary shares
effected by Biotech Target during the past sixty days is attached
Page 4 of 5 Pages
<PAGE> 5
hereto as Exhibit A and such information is incorporated herein by reference.
(e) As of March 19, 1997, BB Biotech and Biotech Target ceased to
have beneficial ownership of more than 5 percent of Xenova's outstanding
ordinary shares.
SIGNATURES
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
BB BIOTECH AG
Date: April 18, 1997 By:/s/ Hans-Joerg Graf*
--------------------
Name: Hans-Joerg Graf
Date: April 18, 1997 By:/s/ Dr. Victor Bischoff*
------------------------
Name: Dr. Victor Bischoff
BIOTECH TARGET, S.A.
Date: April 18, 1997 By:/s/ Dr. Andreas Bremer
----------------------
Name: Dr. Andreas Bremer
Date: April 18, 1997 By:/s/ Dr. Anders Hove
-------------------
Name: Dr. Anders Hove
- ----------------
* See power of attorney, attached as an exhibit 99.E to the Schedule 13D
relating to Biogen, Inc. filed with the Securities and Exchange Commission on
June 2, 1994, which exhibit is incorporated by reference herein.
Page 5 of 5 Pages
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Exhibit A
EXHIBIT A IS HEREBY AMENDED TO ADD THE FOLLOWING SUMMARY OF
TRANSACTIONS IN XENOVA ORDINARY SHARES EFFECTED BY BIOTECH TARGET
IN THE LAST 60 DAYS.
<TABLE>
<CAPTION>
- --------------------------------------------------------------------------------------------
DATE TYPE OF TRANSACTION AND SALE PRICE BENEFICIALLY PERCENT OF
NUMBER OF SHARES OF SHARES OWNED SHARES OUTSTANDING
PER SHARE OWNED
<C> <C> <C> <C> <C>
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3/6/97 Sale of 250,000 shares 5.04 1,000,000 7.96
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3/11/97 Sale of 125,000 shares 5.02 875,000 6.96
- --------------------------------------------------------------------------------------------
3/13/97 Sale of 60,000 shares 5.12 815,000 6.49
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3/14/97 Sale of 50,000 shares 5.12 765,000 6.09
- --------------------------------------------------------------------------------------------
3/17/97 Sale of 60,000 shares 5.02 705,000 5.61
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3/19/97 Sale of 100,000 shares 5.12 605,000 4.81
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3/21/97 Sale of 120,000 shares 5.12 485,000 3.86
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3/25/97 Sale of 40,000 shares 5.70 445,000 3.54
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3/26/97 Sale of 25,000 shares 5.62 420,000 3.34
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3/27/97 Sale of 60,000 shares 5.62 360,000 2.86
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3/31/97 Sale of 10,000 shares 5.50 350,000 2.79
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4/2/97 Sale of 150,000 shares 5.78 200,000 1.59
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4/7/97 Sale of 20,000 shares 5.75 180,000 1.43
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4/8/97 Sale of 10,000 shares 5.75 170,000 1.35
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4/11/97 Sale of 10,000 shares 5.75 160,000 1.27
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4/15/97 Sale of 60,000 shares 5.62 100,000 0.79
============================================================================================
</TABLE>
