COCENSYS INC
SC 13D, 1996-12-31
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13D

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                               (AMENDMENT NO. 2)*


                                 CoCensys, Inc.
- --------------------------------------------------------------------------------
                               (Name of Issuer)

                          Common Stock, $.001 par value
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                   0001912631
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

       Stephen T. Mears, Testa, Hurwitz & Thibeault, LLP, 125 High Street
                         Boston, MA 02110 (617) 248-7000
- --------------------------------------------------------------------------------
 (Name, Address and Telephone Number of Person Authorized to Receive Notices and
 Communications)

Statement is being filed to reflect ownership of less than 5% of the
class - see Item 5(e).
- --------------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)


If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box [ ].

Check the following box if a fee is being paid with the statement [ ]. (A fee is
not required only if the reporting person:  (1) has a previous statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7.)

NOTE: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule  13d-1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).




                                  SCHEDULE 13D

- --------------------------------------------------------------------------------
CUSIP NO. 0001912631                                      Page  2  of   9 Pages
- --------------------------------------------------------------------------------



- ---------- ---------------------------------------------------------------------
    1      NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Biotechnology Venture Fund, S.A. in Voluntary Liquidation
- ---------- ---------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) [ ]
                                                                        (b) [ ] 

- ---------- ---------------------------------------------------------------------
    3      SEC USE ONLY

- ---------- ---------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           N/A
- ---------- ---------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED         [ ]
           PURSUANT TO ITEMS 2(d) or 2(e)

- ---------- ---------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Luxembourg
- ---------------------------- -------- ------------------------------------------
                                7     SOLE VOTING POWER

         NUMBER OF                    570,000
                             -------- ------------------------------------------
          SHARES                8     SHARED VOTING POWER
       BENEFICIALLY
         OWNED BY                     0
                             -------- ------------------------------------------
           EACH                 9     SOLE DISPOSITIVE POWER
         REPORTING
          PERSON                      570,000
                             -------- ------------------------------------------
           WITH                10     SHARED DISPOSITIVE POWER

                                      0
- ---------- ---------------------------------------------------------------------
   11      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           1,070,674
- ---------- ---------------------------------------------------------------------
   12      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN   [ ] 
           SHARES*

- ---------- ---------------------------------------------------------------------
   13      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           4.8%
- ---------- ---------------------------------------------------------------------
   14      TYPE OF REPORTING PERSON *

           CO
- ---------- ---------------------------------------------------------------------
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
          INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
      (INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE ATTESTATION.






                                  SCHEDULE 13D

- --------------------------------------------------------------------------------
CUSIP NO. 0001912631                                      Page  3  of   9 Pages
- --------------------------------------------------------------------------------


- ---------- ---------------------------------------------------------------------
    1      NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Abingworth Bioventures SICAV

- ---------- ---------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) [ ]
                                                                        (b) [ ] 

- ---------- ---------------------------------------------------------------------
    3      SEC USE ONLY


- ---------- ---------------------------------------------------------------------
    4      SOURCE OF FUNDS*                                                 [ ]

           N/A
- ---------- ---------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED         [ ] 
           PURSUANT TO ITEMS 2(d) or 2(e)

- ---------- ---------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Luxembourg
- ---------- ---------------------------------------------------------------------
                                7     SOLE VOTING POWER

         NUMBER OF                    500,674
                             -------- ------------------------------------------
          SHARES                8     SHARED VOTING POWER
       BENEFICIALLY
         OWNED BY                     0
                             -------- ------------------------------------------
           EACH                 9     SOLE DISPOSITIVE POWER
         REPORTING
          PERSON                      500,674
                             -------- ------------------------------------------
           WITH                10     SHARED DISPOSITIVE POWER

                                      0
- ---------------------------- -------- ------------------------------------------
   11      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           1,070,674
- ---------- ---------------------------------------------------------------------
   12      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN   [ ] 
           SHARES*

- ---------- ---------------------------------------------------------------------
   13      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           4.8%
- ---------- ---------------------------------------------------------------------
   14      TYPE OF REPORTING PERSON *

           CO
- ---------- ---------------------------------------------------------------------
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
          INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
      (INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE ATTESTATION.






                                  SCHEDULE 13D

Item 1.  Security and Issuer.

         This statement  relates to the shares of Common Stock,  $.001 par value
per share (the "Shares"),  of CoCensys, Inc. (the "Issuer") having its principal
executive office at 213 Technology Drive, Irvine, CA 92618.

Item 2.  Identity and Background.

         This statement is being filed by  Biotechnology  Venture Fund,  S.A. in
Voluntary  Liquidation   ("Biotechnology")  and  Abingworth   Bioventures  SICAV
("ABS"). Each of Biotechnology and ABS is a corporation organized under the laws
of Luxembourg  with its principal  business and principal  office located at 231
Val des Bons Malades,  L-2121  Luxembourg-Kirchberg.  The principal  business of
each of Biotechnology and ABS is venture capital.

         The  directors  and executive  officers of ABS and the  liquidators  of
Biotechnology are Jacques Bemberg,  M. Rose Dock, Paul Meyers, Karl U. Sanne and
Jean Welter (collectively, the "Directors").

         Mr.  Bemberg  resides  at  38,  avenue  de  l'Elysee,   1006  Lausanne,
Switzerland.  Mr. Bemberg is a director of various  companies.  Mr. Bemberg is a
citizen of France.

         Ms.  Dock's  business  address  is Sanne & Cie  Sarl,  231 Val des Bons
Malades, L-2121  Luxembourg-Kirchberg.  She is general manager and a director of
Sanne & Cie Sarl, a trustee and fiduciary  services  firm. Ms. Dock is a citizen
of Luxembourg.

         Mr.  Meyers is the managing  director of Banque  Generale du Luxembourg
S.A., located at 27 avenue Monterey, L-2951 Luxembourg.  Mr. Meyers is a citizen
of Luxembourg.

         Mr.  Sanne is  managing  director  of Sanne & Cie Sarl,  a trustee  and
fiduciary  services  firm,  located  at  231  Val  des  Bons  Malades,   L-2121,
Luxembourg-Kirchberg. He is a citizen of Norway.

         Mr. Welter is a lawyer located at 100 Boulevard de la Petrusse,  L-2320
Luxembourg, and a citizen of Luxembourg.

         During the five years prior to the date hereof,  neither Biotechnology,
ABS nor any of the Directors has been convicted in a criminal  proceeding or has
been a party to a civil proceeding  ending in a judgment,  decree or final order
enjoining future violations of, or prohibiting or mandating  activities  subject
to,  federal or state  securities  laws or finding any violation with respect to
such laws.

Item 3.  Source and Amount of Funds or Other Consideration.

         Not applicable. This statement is being filed to report dispositions of
Shares.

Item 4.  Purpose of Transaction.

         This  statement  is  being  filed to  report  dispositions  of  Shares.
Depending on market conditions,  their continuing evaluation of the business and
prospects of the Issuer and other factors,  



                               Page 4 of 9 Pages





ABS and/or Biotechnology may dispose of or acquire additional Shares.  Except as
set forth above,  neither ABS,  Biotechnology  nor any of the  Directors has any
present plans which relate to or would result in:

         (a)      The acquisition by any person of additional  securities of the
                  Issuer, or the disposition of securities of the Issuer;

         (b)      An  extraordinary  corporate  transaction,  such as a  merger,
                  reorganization or liquidation,  involving the Issuer or any of
                  its subsidiaries;

         (c)      A sale or transfer of material  amount of assets of the Issuer
                  or any of its subsidiaries;

         (d)      Any change in the present  board of directors or management of
                  the Issuer,  including  any plans or  proposals  to change the
                  number or term of directors or to fill any existing  vacancies
                  on the board;

         (e)      Any material change in the present  capitalization or dividend
                  policy of the Issuer;

         (f)      Any  other  material  change  in  the  Issuer's   business  or
                  corporate structure;

         (g)      Changes  in  the  Issuer's  charter,   bylaws  or  instruments
                  corresponding  thereto or other  actions  which may impede the
                  acquisition of control of the Issuer by any person;

         (h)      Causing a class of  securities  of the  Issuer to be  delisted
                  from  a  national  securities  exchange  or  to  cease  to  be
                  authorized to be quoted in an inter-dealer quotation system of
                  a registered national securities association;

         (i)      A class of equity  securities of the Issuer becoming  eligible
                  for termination of registration  pursuant to section  12(g)(4)
                  of the Securities Exchange Act of 1934; or

         (j)      Any action similar to any of those enumerated above.

Item 5.  Interest in Securities of the Issuer.

         (a)      Biotechnology  and  ABS  may be  deemed  to  beneficially  own
                  1,070,674  Shares as of the date hereof.  Biotechnology is the
                  record owner of 570,000 Shares (the  "Biotechnology  Shares").
                  ABS is the record owner of 376,384  Shares (the "ABS Shares").
                  In addition, ABS may be deemed to beneficially own the 124,290
                  Shares  (the  "Warrant  Shares")  issuable  to  ABS  upon  the
                  exercise of currently  exercisable warrants which ABS holds of
                  record.  (The  Biotechnology  Shares,  the ABS  Shares and the
                  Warrant  Shares are  referred  to  collectively  herein as the
                  "Record   Shares").   By  virtue  of  their   relationship  as
                  affiliated corporations with the same individuals as directors
                  or liquidators,  Biotechnology  and ABS may be deemed to share
                  the  power to  direct  the vote and the  power to  direct  the
                  disposition of the Record Shares. Hence, each of Biotechnology
                  and ABS may be deemed to  beneficially  own 1,070,674  Shares,
                  representing beneficial ownership of approximately 4.8% of the
                  Issuer's  issued and  outstanding  Common  Stock  based 



                               Page 5 of 9 Pages





                  on  the  22,014,656  Shares  of  the  Issuer  reported  to  be
                  outstanding in the quarterly report on Form 10-Q of the Issuer
                  for the quarter ended September 30, 1996, as adjusted pursuant
                  to Rule  13d-3(d)(1).  However,  each of Biotechnology and ABS
                  disclaims  beneficial  ownership of any Shares except for that
                  number of Shares that it holds of record or that are  issuable
                  to it upon the  exercise of warrants  that it holds of record:
                  Biotechnology: 570,000 Shares; ABS: 500,674 Shares.

                  None of the  Directors  beneficially  owns any  Shares  of the
Issuer.

         (b)      Regarding the number of shares as to which such person has:

                  (i)      sole power to vote or to direct the vote:

                           Biotechnology:  570,000 Shares; ABS:  500,674 Shares;
                           Each of the Directors:  -0- Shares.

                  (ii)     shared power to vote or to direct the vote:

                           Biotechnology:  -0- Shares; ABS:  -0- Shares;
                           Each of the Directors:  -0- Shares.

                  (iii)    sole power to dispose or to direct the disposition:

                           Biotechnology:  570,000 Shares; ABS:  500,674 Shares;
                           Each of the Directors:  -0- Shares.

                  (iv)     shared power to dispose or to direct the disposition:

                           Biotechnology:  -0- Shares; ABS:  -0- Shares;
                           Each of the Directors:  -0- Shares.

             (c) During  the 60 days  prior  to the  date  hereof,  ABS sold the
                 following amounts of Shares in the open market on the following
                 dates at the following per share prices:

           Date                         Shares                   Price Per Share
           ----                         ------                   ---------------
    November 25, 1996                   5,000                         $6.00
    November 26, 1996                   32,900                        $6.00
    November 27, 1996                   12,100                       $6.0625
    December 3, 1996                    15,300                        $6.00
    December 4, 1996                    5,300                         $6.00
    December 5, 1996                    6,600                         $6.00
    December 11, 1996                   6,800                         $6.00
    December 16, 1996                   11,000                        $6.00
    December 17, 1996                   5,000                         $6.00

         (d)      No other  person is known to have the right to  receive or the
                  power to direct the receipt of dividends from, or any proceeds
                  from the sale of, Shares  beneficially  owned by Biotechnology
                  and ABS.



                               Page 6 of 9 Pages





         (e)      Biotechnology  and ABS  ceased to be the  beneficial  owner of
                  more than five percent of the Shares on December 3, 1996.

Item 6.  Contracts, Arrangements, Understandings or Relationships with Respect 
         to Securities of the Issuer.

         Except  as  described   elsewhere  herein,   there  are  no  contracts,
arrangements,   understandings  or  relationships  (legal  or  otherwise)  among
Biotechnology,  ABS and the  Directors or between any such persons and any other
person with respect to any Shares,  including but not limited to the transfer or
voting of any of the  Shares,  finder's  fees,  joint  ventures,  loan or option
arrangements,  puts or calls,  guarantees  of  profits,  division  of profits or
losses or the giving or withholding of proxies.

Item 7.  Material to be Filed as Exhibits.

         Exhibit 1 - Agreement regarding filing of joint Schedule 13D.



                                Page 7 of 9 Pages






                                    SIGNATURE
                                    ---------

         After  reasonable  inquiry and to the best of its knowledge and belief,
each of the  undersigned  certifies  that  the  information  set  forth  in this
statement is true, complete and correct.

Date:    December 24, 1996

BIOTECHNOLOGY VENTURE FUND, S.A. (i.l.)

By: /s/ Karl U. Sanne
    ----------------------------------------------------    
    Name:  Karl U. Sanne

Title:   Liquidator

By: /s/ Fernand Heim
    ----------------------------------------------------    
    Name:  Fernand Heim

Title:   Mandatory

ABINGWORTH BIOVENTURES SICAV

By: /s/ Karl U. Sanne
    ----------------------------------------------------    
    Name:  Karl U. Sanne

Title:   Director

By: /s/ Fernand Heim
    ----------------------------------------------------    
    Name:  Fernand Heim

Title:   Mandatory


                                Page 8 of 9 Pages


  




                                                                       Exhibit 1
                                                                       ---------

                                    AGREEMENT

         Pursuant to Rule 13d-1(f)(1) under the Securities Exchange Act of 1934,
the undersigned hereby agree that only one statement  containing the information
required by Schedule 13D need be filed with respect to the  ownership by each of
the undersigned of shares of stock of CoCensys, Inc.

         This Agreement may be executed in any number of  counterparts,  each of
which shall be deemed an original.

         EXECUTED this 24th day of December, 1996.

BIOTECHNOLOGY VENTURE FUND, S.A. (i.l.)

By: /s/ Karl U. Sanne
   -----------------------------------------------------    
    Name:  Karl U. Sanne

Title:   Liquidator

By: /s/ Fernand Heim
    ----------------------------------------------------    
    Name:  Fernand Heim

Title:   Mandatory

ABINGWORTH BIOVENTURES SICAV

By: /s/ Karl U. Sanne
    ----------------------------------------------------    
    Name:  Karl U. Sanne

Title:   Director

By: /s/ Fernand Heim
    ----------------------------------------------------    
    Name:  Fernand Heim

Title:   Mandatory



209STM141/1.300182-1




                                Page 9 of 9 Pages





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