COCENSYS INC
10-Q, 1998-11-09
PHARMACEUTICAL PREPARATIONS
Previous: DISCOVER CARD MASTER TRUST I, 424B5, 1998-11-09
Next: CHESAPEAKE ENERGY CORP, 8-K, 1998-11-09





<PAGE>

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

                       SECURITIES AND EXCHANGE COMMISSION

                              WASHINGTON, DC 20549

                                    FORM 10-Q

(Mark One)

[X]   QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE
      SECURITIES EXCHANGE ACT OF 1934

                FOR THE QUARTERLY PERIOD ENDED SEPTEMBER 30, 1998

                                       OR

[   ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
      SECURITIES EXCHANGE ACT OF 1934

               For the transition period from ________ to ________

                         Commission File Number 0-20954

                                 COCENSYS, INC.
                          (EXACT NAME OF REGISTRANT AS
                            SPECIFIED IN ITS CHARTER)

                     DELAWARE                           33-0538836
            (STATE OR OTHER JURISDICTION OF        (I.R.S. EMPLOYER
             INCORPORATION OR ORGANIZATION)        IDENTIFICATION NO.)

                     201 TECHNOLOGY DRIVE, IRVINE, CA 92618
          (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES, INCLUDING ZIP CODE)

                                 (949) 753-6100
              (REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15 (d) of the Securities Exchange Act of 1934
during the preceding 12 months (or for such shorter period that the registrant
was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.

      Yes    X      No
           ------      ------


Indicate the number of shares outstanding of each of the issuer's classes of
common stock, as of the latest practicable date.

            $.001 PAR VALUE                       27,231,157
        (CLASS OF COMMON STOCK)           (OUTSTANDING AT NOVEMBER 5, 1998)

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

                                TABLE OF CONTENTS
<TABLE>
<CAPTION>

                                                                                 PAGE NUMBER
<S>           <C>                                                                <C>
PART I.       FINANCIAL INFORMATION

              ITEM 1.  FINANCIAL STATEMENTS.

                          Condensed Balance Sheets as of September 30, 1998
                          and December 31, 1997                                       3

                          Condensed Statements of Operations for the three and
                          nine-month periods ended September 30, 1998 and 1997
                          and the period from inception (February 15, 1989)
                          through September 30, 1998                                  4

                          Condensed Statements of Cash Flows for the nine-month
                          periods ended September 30, 1998 and 1997 and the
                          period from inception (February 15, 1989) through
                          September 30, 1998                                          5

                          Notes to Condensed Financial Statements                     6

              ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
                       CONDITION AND RESULTS OF OPERATIONS.                          12

PART II.      OTHER INFORMATION

              ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K.                             18


SIGNATURES                                                                           19
</TABLE>

                                       2

<PAGE>





                                 COCENSYS, INC.
                          (A development stage company)

                            CONDENSED BALANCE SHEETS
               (In thousands, except share and par value amounts)
<TABLE>
<CAPTION>
                                                      SEPTEMBER 30,   DECEMBER 31,
                                                          1998             1997
                                                      -------------   ------------
                                                       (Unaudited)
<S>                                                   <C>            <C>  
ASSETS
Current assets:
  Cash and cash equivalents                              $   4,246   $  3,410
  Short-term investments                                    10,827      9,050
  Receivables from corporate partners                           14        414
  Other current assets                                         348        484
                                                         ---------   --------
TOTAL CURRENT ASSETS                                        15,435     13,358

Property and equipment, net                                  2,596      2,823
Investments                                                    500        500
Other assets, net                                              150        235
                                                         ---------   --------
                                                         $  18,681   $ 16,916
                                                         ---------   --------
                                                         ---------   --------

LIABILITIES & STOCKHOLDERS' EQUITY 
Current liabilities:
  Accounts payable                                       $     383   $    866
  Other accrued liabilities                                  1,045      1,911
  Accrued compensation and benefits                            837      1,107
  Deferred revenue                                           2,575         --
  Due to corporate partners                                  1,498        747
  Capital lease obligation - current portion                   334        353
                                                         ---------   --------
TOTAL CURRENT LIABILITIES                                    6,672      4,984

Capital lease obligation, less current portion                 359        567
Other liabilities                                              528        534

Commitments and contingencies

Stockholders' equity:
  Preferred stock - $.001 par value,
    5,000,000 shares authorized; 207,095 shares
    issued and outstanding at September 30, 1998 and
    214,286 at December 31, 1997                            16,664     13,000
Common stock - $.001 par value,
    75,000,000 shares authorized; 25,709,758 shares
    issued and outstanding at September 30, 1998 and
    22,857,506 at December 31, 1997                        106,667     97,230
Deficit accumulated during the development stage          (112,117)   (98,983)
Deferred compensation                                         (174)      (430)
Accumulated comprehensive income                                82         14
                                                         ---------   --------
TOTAL STOCKHOLDERS' EQUITY                                  11,122     10,831
                                                         ---------   --------
                                                         $  18,681   $ 16,916
                                                         ---------   --------
                                                         ---------   --------
</TABLE>

                            See accompanying notes.

                                       3
<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

                       CONDENSED STATEMENTS OF OPERATIONS
                    (In thousands, except per share amounts)
                                  (Unaudited)


<TABLE>
<CAPTION>

                                                                                          
                                                                                             PERIOD FROM
                                                                                              INCEPTION
                                                    THREE MONTHS ENDED   NINE MONTHS ENDED  (FEBRUARY 15,
                                                       SEPTEMBER 30,        SEPTEMBER 30,     1989) TO
                                                   -------------------   -----------------  SEPTEMBER 30,
                                                     1998       1997        1998      1997       1998
                                                   --------   --------   --------   --------   ---------
<S>                                                <C>        <C>        <C>        <C>        <C>      
REVENUES
  Co-promotion revenues from corporate partners    $      -   $    861   $    540   $  3,169   $  30,705
  Co-development revenues from corporate partners       325        951      1,346      7,900      18,039
                                                   --------   --------   --------   --------   ---------
Total revenues                                          325      1,812      1,886     11,069      48,744
                                                   --------   --------   --------   --------   ---------

OPERATING EXPENSES
  Research and development                            4,380      5,781     11,801     17,198     102,730
  Marketing, general and administrative               1,017      2,855      3,049      8,358      51,205
  Acquired research and development                      --         --         --         --      14,879
                                                   --------   --------   --------   --------   ---------
Total operating expenses                              5,397      8,636     14,850     25,556     168,814
                                                   --------   --------   --------   --------   ---------
OPERATING LOSS                                       (5,072)    (6,824)   (12,964)   (14,487)   (120,070)

Gain on disposition of sales division                    --         --        750         --       5,478
Interest income                                         261        230        695        638       5,148
Interest expense                                        (20)       (16)       (64)       (67)     (1,122)
                                                   --------   --------   --------   --------   ---------

NET LOSS                                             (4,831)    (6,610)   (11,583)   (13,916)   (110,566)
Dividends on preferred stock                          1,060         --      1,551         --       1,551
                                                   --------   --------   --------   --------   ---------

Net loss attributable to common shareholders       $ (5,891)  $ (6,610)  $(13,134)  $(13,916)  $(112,117)
                                                   --------   --------   --------   --------   ---------
                                                   --------   --------   --------   --------   ---------
Net loss per share                                 $  (0.24)  $  (0.29)  $  (0.55)  $  (0.62)
                                                   --------   --------   --------   --------  
                                                   --------   --------   --------   --------  
Shares used in computing net loss per share          24,717     22,707     23,791     22,497
                                                   --------   --------   --------   --------  
                                                   --------   --------   --------   --------  

</TABLE>

                            See accompanying notes.

                                       4


<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                       CONDENSED STATEMENTS OF CASH FLOWS
                                 (In thousands)
                                   (Unaudited)

<TABLE>
<CAPTION>
                                                                                             PERIOD
                                                                                              FROM
                                                                                            INCEPTION
                                                                       NINE MONTHS ENDED   (FEBRUARY 15,
                                                                          SEPTEMBER 30,      1989) TO
                                                                       ------------------- SEPTEMBER 30,
                                                                          1998       1997       1998
                                                                        --------   --------   ---------
<S>                                                                     <C>        <C>        <C>       
OPERATING ACTIVITIES
Net loss                                                                $(11,583)  $(13,916)  $(110,566)
Adjustments to reconcile net loss to net cash used in operating
activities:
  Depreciation and amortization                                              681        776       7,506
  Amortization of deferred compensation                                      255        203       3,862
  Issuance of stock and warrants for services                                 74         55       2,410
  Loss on sale of fixed assets                                                --         65         100
  Gain on disposition of sales force                                        (750)        --      (5,478)
  Acquired research and development                                           --         --      12,279
  Decrease (increase) in other current assets                                136        157        (420)
  Decrease (increase) in receivable from corporate partner                   400        589         (14)
  Increase (decrease) in advances from corporate partners                    751       (446)      1,498
  Increase in deferred revenue                                             2,575         --       2,575
  Increase (decrease) in accounts payable and other accrued
   liabilities                                                            (1,624)    (1,204)      1,142
                                                                        --------   --------   ---------
NET CASH USED IN OPERATING ACTIVITIES                                     (9,085)   (13,721)    (85,106)
                                                                        --------   --------   ---------
INVESTING ACTIVITIES

Decrease (increase) in short-term investments                             (1,709)     9,092     (10,745)
Purchase of property and equipment                                          (454)      (931)     (7,554)
Decrease (increase) in other assets and notes receivable from officers        85       (159)     (1,306)
Cash received on disposition of sales division                               750         --       8,750
Cash received on sale of fixed assets                                         --          1          20
Increase in deferred costs                                                    --         --      (2,475)
Purchase of investments                                                       --         --        (500)
Acquisition of Acea Pharmaceuticals, net of cash acquired                     --         --         (62)
                                                                        --------   --------   ---------
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES                       (1,328)     8,003     (13,872)
                                                                        --------   --------   ---------
FINANCING ACTIVITIES

Net cash proceeds from issuance of common stock                              156      2,329      61,401
Net cash proceeds from issuance of preferred stock                        11,320      5,000      40,701
Proceeds from sale/leaseback of fixed assets and notes payable               163        529       5,398
Payments on capital lease obligations and notes payable                     (390)      (677)     (4,276)
                                                                        --------   --------   ---------
NET CASH PROVIDED BY FINANCING ACTIVITIES                                 11,249      7,181     103,224
                                                                        --------   --------   ---------

NET INCREASE IN CASH AND CASH EQUIVALENTS                                    836      1,463       4,246
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD                           3,410      1,050          --
                                                                        --------   --------   ---------
CASH AND CASH EQUIVALENTS AT END OF PERIOD                              $  4,246   $  2,513   $   4,246
                                                                        --------   --------   --------- 
                                                                        --------   --------   ---------
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION

Cash paid for interest                                                  $     65   $     55   $     885
                                                                        --------   --------   ---------
                                                                        --------   --------   ---------
</TABLE>

                            See accompanying notes.

                                       5

<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

                               SEPTEMBER 30, 1998
                                   (UNAUDITED)

1.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

     BASIS OF PRESENTATION

     CoCensys, Inc. ("CoCensys" or the "Company") is a biopharmaceutical company
     dedicated to the discovery and development of small molecule drugs to treat
     neurological and psychiatric disorders. The interim financial information
     for the three and nine-month periods ended September 30, 1998 and 1997 is
     unaudited but includes all adjustments (consisting only of normal recurring
     entries) that the Company's management believes to be necessary for the
     fair presentation of the financial position, results of operations and cash
     flows for the periods presented. The accompanying interim financial
     statements should be read in conjunction with the financial statements and
     related notes included in the Company's Annual Report on Form 10-K for the
     year ended December 31, 1997. Certain information and footnote disclosures
     normally included in financial statements prepared in accordance with
     generally accepted accounting principles have been condensed or omitted
     pursuant to Securities and Exchange Commission rules and regulations.
     Interim results of operations for the three- and nine-month periods ended
     September 30, 1998, are not necessarily indicative of operating results to
     be expected for the full year.

     REVENUE AND EXPENSE RECOGNITION

     See Notes 2, 3, 4, 5 and 6 for revenue recognition policies related to
     co-promotion and co-development revenues from corporate partners.

     NET LOSS PER SHARE

     In 1997, Statement of Financial Accounting Standards No. 128, "Earnings per
     Share" ("SFAS 128"), replaced the calculation of primary and fully diluted
     earnings per share with basic and diluted earnings per share. Unlike
     primary earnings per share, basic earnings per share excludes any dilutive
     effect of options, warrants and convertible securities. All per share
     amounts for all prior periods have been presented and, where appropriate,
     restated to conform to the SFAS 128 requirements.

     Both basic and diluted loss per share are computed using the weighted
     average number of shares of common stock outstanding. Common equivalent
     shares from stock options, warrants and convertible securities are excluded
     from the computation of diluted earnings per share, as their effect would
     be antidilutive.


                                       6
<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

     COMPREHENSIVE INCOME

     As of January 1, 1998, the Company adopted Statement of Financial
     Accounting Standards No. 130, "Reporting Comprehensive Income" (SFAS 130).
     SFAS 130 establishes new rules for the reporting and display of
     comprehensive income and its components; however, the adoption of this
     Statement had no impact on the Company's net income or stockholders'
     equity. SFAS 130 requires unrealized gains and losses on available-for-sale
     securities, which prior to adoption were reported separately on
     stockholders' equity, to be included in other comprehensive income. Prior
     financial statements have been restated to conform to the requirements of
     SFAS 130.

     The components of comprehensive loss are as follows (in thousands):


<TABLE>
<CAPTION>
                                                                                               PERIOD FROM
                                                                                                INCEPTION
                                                    THREE MONTHS ENDED   NINE MONTHS ENDED    (FEBRUARY 15,
                                                       SEPTEMBER 30,        SEPTEMBER 30,       1989) TO
                                                   -------------------   -----------------    SEPTEMBER 30,
                                                     1998       1997        1998      1997         1998
                                                   --------   --------   --------   --------     ---------
<S>                                                <C>        <C>        <C>        <C>        <C>      
Net loss                                           $  (5,891) $  (6,610) $  (13,134) $  (13,916) $  (112,117)
Unrealized gain on investments                            99          9          81          23           82
                                                   ---------  ---------- ----------  ----------  -----------
Comprehensive loss                                 $  (5,792) $  (6,601) $  (13,053) $  (13,893) $  (112,035)
                                                   ---------  ---------- ----------  ----------  -----------
                                                   ---------  ---------- ----------  ----------  -----------
</TABLE>

     PENDING ADOPTION OF FINANCIAL ACCOUNTING STANDARDS NO. 131

     In June 1998, the Financial Accounting Standards Board issued Financial
     Accounting Standards No. 131, "Disclosures about Segments of an Enterprise
     and Related Information" (SFAS 131). SFAS 131 establishes standards for the
     way that public business enterprises report information about segments in
     annual financial statements and requires that those enterprises report
     selected information about operating segments in interim financial reports.
     SFAS 131 also establishes standards for related disclosures about products
     and services, geographic areas and major customers. SFAS 131 is effective
     for financial statements for fiscal years beginning after December 15,
     1997, and therefore the Company will adopt the new requirements effective
     with filing of the Annual Report on Form 10-K for the year ended December
     31, 1998. Management has not completed its review of SFAS 131, but does not
     expect that it will have an impact on the Company's results of operations,
     financial position or cash flows.

2.   DISPOSITION OF SALES AND MARKETING DIVISION

                                       7

<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS


     On October 8, 1997, the Company entered into an Asset Purchase Agreement
     (the "Agreement") to sell its sales and marketing division (the "Division")
     to Watson Laboratories, Inc. ("Watson"), a wholly owned subsidiary of
     Watson Pharmaceuticals, Inc. Under the terms of the Agreement, Watson
     assumed the Division's co-promotion agreements, acquired certain of its
     operating assets and obtained the right to hire approximately 70 employees
     of the Division. As consideration for these assets, the Company received
     $8.0 million from Watson in October 1997 with up to $1.0 million more due
     to the Company if Watson retained, as of specified future dates, certain
     percentages of the employees from the Division. Pursuant to this
     contingency arrangement, Watson paid CoCensys $750,000 in April 1998 and
     $250,000 in October 1998.

     In order to satisfy certain provisions of the Agreement, the Company
     entered into, and transferred to Watson, agreements with two pharmaceutical
     companies for marketing rights and NDAs for two drugs with an aggregate
     cost of $2.0 million. Of this total, the Company paid $1.0 million in
     October 1997. Additionally, $1.0 million of the $8.0 million of proceeds
     from the sale of the Division was placed into an escrow account to satisfy
     the future obligations related to these acquisitions. In October 1998,
     $500,000 of the funds held in escrow was disbursed.

3.   DEVELOPMENT AND COMMERCIALIZATION AGREEMENT WITH WYETH-AYERST
     LABORATORIES

     In May 1997, the Company entered into a development and commercialization
     agreement for Co 2-6749, its lead anxiolytic compound, with the
     Wyeth-Ayerst Laboratories Division ("Wyeth-Ayerst") of American Home
     Products Corporation ("AHP"). Under the terms of the agreement,
     Wyeth-Ayerst paid CoCensys a non-refundable $5.0 million licensing fee and
     AHP paid $5.0 million to purchase 100,000 shares of the Company's Series C
     Convertible Preferred Stock. Additionally, CoCensys will receive specified
     milestone payments dependent upon the achievement of key development events
     and $750,000 per quarter for up to three years to identify back-up
     compounds. However, if Co 2-6749 fails to meet certain criteria, and the
     back-up program fails to produce a back-up compound that meets other
     certain criteria, Wyeth-Ayerst has the right to terminate the back-up
     program and require CoCensys to reimburse them for a portion of the back-up
     funding. Accordingly, a portion of the back-up program funding has been
     recorded as deferred revenue and will be recognized as revenue when Co
     2-6749 or a back-up compound meets applicable criteria for acceptance by
     Wyeth-Ayerst.

     Wyeth-Ayerst is responsible for the costs associated with developing Co
     2-6749. The Company and Wyeth-Ayerst will co-promote any resulting product
     in certain market segments in the United States, while Wyeth-Ayerst will
     have rights to develop, register and market any drugs derived from the
     collaboration in the rest of the world, subject to royalty obligations to
     CoCensys. The preferred stock is convertible into common stock after May
     12, 1999, at a conversion price based on the market price of the common
     stock at that time (subject to certain minimum and maximum limits).

                                       8
<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

4.   MARKETING AND DEVELOPMENT COLLABORATION WITH WARNER-LAMBERT COMPANY

     In October 1995, the Company entered into collaboration with Warner-Lambert
     Company ("Warner-Lambert") and its Parke-Davis division to develop and
     market therapeutic drugs for the treatment of certain central nervous
     system disorders. This arrangement consists of the Research, Development
     and Marketing Collaboration Agreement (the "1995 Warner Collaboration
     Agreement"), for the worldwide development and commercialization of a new
     class of neurological and psychiatric drugs, termed subtype selective NMDA
     receptor antagonists ("SSNRAs"), and the Parke-Davis Promotion Agreement.
     Pursuant to the Parke-Davis Promotion Agreement, the Company co-promoted
     Parke-Davis' central nervous system drug, Cognex-Registered Trademark-, 
     until June 1997 when Parke-Davis terminated the co-promotion agreement. 
     In addition, in October 1997, the 1995 Warner Collaboration Agreement was 
     amended and extended until at least October 1999 (the "amended Warner 
     Collaboration Agreement").

     Under the amended Warner Collaboration Agreement, both companies share
     technology and resources to develop SSNRA candidates. Warner is obligated
     to pay for all costs to develop any development candidates arising from the
     Agreement, subject to CoCensys' right to re-engage in the development by
     funding a percentage of the development costs. Warner is also obligated to
     pay for all costs to promote any product developed under the Warner
     Collaboration Agreement, subject to CoCensys' right to co-promote in the
     United States (including sharing of costs to promote) any product for which
     CoCensys re-engaged development rights. CoCensys will receive royalties on
     sales of any products developed under the Warner Collaboration Agreement,
     at rates based in part upon whether CoCensys co-developed and co-promoted
     such product. In addition, upon achievement of certain clinical development
     and regulatory milestones, Warner will make nonrefundable milestone
     payments to CoCensys. Payments received under the amended Warner
     Collaboration Agreement are recognized as co-development revenues and
     payments made are recognized as expenses.

     Pursuant to the 1995 Warner Collaboration Agreement,
     Warner-Lambert purchased $2.0 million of CoCensys Common Stock in October
     1995 and an additional $2.0 million of CoCensys Common Stock in March 1997.

     In October 1997, in connection with the amended Warner Collaboration
     Agreement, Warner-Lambert purchased convertible preferred stock from the
     Company with a face value of $7.0 million. Warner-Lambert paid the Company
     $1.0 million of the $7.0 million total in October 1997 and $6.0 million in
     January 1998. The Company allocated $1.6 million to be recognized as
     co-development revenue during fiscal 1998, $4.4 million as preferred stock
     and $1.0 million as a liability (payable in common stock) due to
     Warner-Lambert in January 1999. The preferred stock accrues an imputed
     non-cash dividend at 12 percent per annum until its mandatory conversion
     date in October 2001 and is convertible at the price of the common stock at
     the time of conversion (subject to a limit on the maximum number of shares
     that may be issued). The Company may elect to force conversion at an
     earlier date at a price equal to the greater of the then current price or
     the price when issued.

                                       9

<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

5.   DEVELOPMENT AND COMMERCIALIZATION AGREEMENT WITH G.D. SEARLE & CO.

     In May 1996, the Company entered into an agreement with G.D. Searle & Co.
     ("Searle") to co-develop and co-promote CCD 3693, the Company's lead
     compound for the treatment of insomnia along with its back-up compounds.
     Pursuant to the agreement, Searle paid a $3.0 million license fee and
     purchased 100,000 shares of the Company's Series B Convertible Preferred
     Stock for $7.0 million. The license fee was recognized as co-development
     revenue in 1996. In May 1998, the Series B Convertible Preferred Stock
     converted, in accordance with its terms, into 1.6 million shares of common
     stock at a conversion price of $4.375 per share.

     In July 1998, Searle notified CoCensys that it had decided not to
     participate further in the development of the Company's proprietary
     compounds for the treatment of insomnia. CoCensys intends to continue
     research and development of its compounds to treat insomnia and will
     consider seeking a new partner for the program in the future.

6.   PROMOTION AGREEMENT WITH SOMERSET PHARMACEUTICALS, INC.

     In January 1996, the Company and Somerset Pharmaceuticals, Inc.
     ("Somerset") entered into the Somerset Promotion Agreement, pursuant to
     which the Company, through its sales and marketing division, promoted
     Somerset's drug Eldepryl-Registered Trademark- to neurologists in the 
     United States for the treatment of Parkinson's disease. Effective 
     January 1, 1997, the initial agreement was superseded by the 1997 Somerset
     Promotion Agreement. Under the 1997 Somerset Promotion Agreement, CoCensys 
     had the exclusive right to detail Eldepryl to certain neurologists and 
     other physicians in the United States and was compensated based upon the 
     number of details undertaken and gross sales of Eldepryl. In October 1997 
     the Company sold its sales and marketing division, and all related 
     co-promotion agreements, to Watson. In March 1998, the Company received 
     and recognized a $540,000 bonus for 1997 sales of Eldepryl. The Company 
     does not expect to receive any more payments pursuant to the Somerset 
     agreement.

7.   CYTOVIA LICENSING AGREEMENT

     In January 1998, the Company licensed certain non-core technology to
     Cytovia, Inc., a new company that will focus on the commercialization of
     patented drug screening technology, using living cells, in the area of
     apoptosis or programmed cell death. In exchange, CoCensys received shares
     of common stock of Cytovia, will be entitled to receive certain royalties
     and will retain certain rights relating to the development of future
     therapeutic agents for central nervous system disorders. As of September
     30, 1998, CoCensys' interest in Cytovia was less than twenty percent and is
     accounted for on a cost basis.

                                       10

<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

8.   PRIVATE PLACEMENT OF PREFERRED STOCK

     In June 1998, the Company raised $8.0 million through the private placement
     of convertible preferred stock. The preferred stock is convertible into
     common stock on June 8, 2001, or earlier at the holder's option at a price
     based on the value of the common stock, subject to a maximum price of $3.93
     per share. The terms of the private placement included the issuance of
     warrants to purchase 350,000 shares of common stock at $4.50 per share,
     with additional warrants to be issued for 100,000 shares of common stock if
     investors hold a specified amount of preferred stock for at least five
     months following purchase.

     The preferred stock carries an annual dividend of 7.5 percent of the face
     value of the outstanding shares, subject to reductions in the dividend rate
     if the market price of Company's common stock increases to certain levels.
     Dividends are payable quarterly in cash or, at the election of the Company,
     by adding the amount of the dividend to the conversion value of the
     preferred stock. Additionally, $390,000 of the $8.0 million in proceeds was
     allocated to the warrants and $890,000 was allocated to a beneficial
     conversion feature that allows investors to convert at 90% of the market
     price of the common stock after 122 days. These two allocated amounts have
     been credited to additional paid in capital and will be treated as issuance
     discounts. Accordingly, the $390,000 and $890,000 will be amortized over
     three years and 122 days, respectively, in the form of additional noncash
     preferred dividends.

9.   SUBSEQUENT EVENT

     On October 16, 1998, the Company announced results from its Phase II
     clinical trial using a tablet formulation of ganaxolone for acute migraine.
     While the patients receiving ganaxolone reported pain relief at a rate in
     excess of those receiving placebo, the difference was not statistically
     significant. The Company did achieve statistically significant results in
     pain relief at two hours in a subset of forty-five female patients who were
     dosed with ganaxolone or placebo within five days following start of
     menses. Based on the results of the trial, the Company intends to seek a
     collaboration partner to develop ganaxolone for migraine prophylaxis as
     well as for epilepsy, for which the drug has shown promising results in
     previous clinical trials. The Company also will seek a collaboration
     partner to develop backup compounds to ganaxolone for acute migraine
     therapy.


                                       11

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)


     ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
             AND RESULTS OF OPERATIONS

     EXCEPT FOR THE HISTORICAL INFORMATION CONTAINED HEREIN, THE FOLLOWING
     DISCUSSION CONTAINS FORWARD-LOOKING STATEMENTS THAT INVOLVE RISKS AND
     UNCERTAINTIES. THE COMPANY'S ACTUAL RESULTS COULD DIFFER MATERIALLY.
     FACTORS THAT COULD CAUSE OR CONTRIBUTE TO SUCH DIFFERENCES INCLUDE, BUT ARE
     NOT LIMITED TO, THOSE DISCUSSED BELOW AND IN THE COMPANY'S 1997 ANNUAL
     REPORT ON FORM 10-K.

     OVERVIEW

     CoCensys, Inc. is a biopharmaceutical company dedicated to the discovery
     and development of small molecule drugs to treat neurological and
     psychiatric disorders. The Company's product discovery and development
     programs are focused on the exploration of novel receptors and enzymes and
     their ligands and inhibitors through three technology platforms: GABA
     receptor modulators named Epalons; glutamate receptor antagonists; and
     sodium channel blockers.

     Since its inception in February 1989, the Company has devoted substantially
     all of its resources to the discovery and development of
     neuropharmaceutical products for the treatment of disorders affecting the
     central nervous system. The Company has incurred losses since inception and
     expects losses to continue for the foreseeable future, primarily due to the
     expansion of programs for research and development. Operating results are
     expected to fluctuate as a result of uncertainty in the timing and amount
     of revenues to be earned from achievement of research and development
     milestones, and uncertainty in the timing and amount of expenses for
     product development, including clinical trials. As of September 30, 1998,
     the Company's accumulated deficit was approximately $112.1 million.

     RESULTS OF OPERATIONS

     The Company recognized no co-promotion revenues for the three-month period
     ended September 30, 1998, and $540,000 for the nine-month period ended
     September 30, 1998, compared to $861,000 and $3.2 million during the same
     periods in fiscal 1997. In October 1997, the Company sold its sales and
     marketing division to Watson Pharmaceuticals, Inc. ("Watson") and is no
     longer involved in co-promotional activities. The 1998 co-promotion revenue
     is attributable to a bonus for fiscal 1997 activity that was received and
     recognized in March 1998.

     The Company recognized $325,000 and $1.3 million in co-development revenues
     for the three and nine-month periods ended September 30, 1998,
     respectively, compared to $951,000 and $7.9 million for the same periods in
     1997. In 1998, co-development revenues are primarily associated with the
     SSNRA (subtype-selective NMDA receptor antagonists) program with
     Warner-Lambert. In the second quarter of 1997, the Company recognized $5.8
     million related to an agreement with Wyeth-Ayerst to co-develop the
     Company's anxiolytic compound.

                                       12

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

     Research and development expenses decreased to $4.4 and $11.8 million for
     the three and nine-month periods ended September 30, 1998, respectively,
     from $5.8 and $17.2 million in the comparable periods of the prior year.
     The decreases in expenses in the current year are attributable to a lower
     level of external clinical activity relative to a year earlier and cost
     savings that resulted from last year's organizational restructuring. In the
     first nine months of 1997, the Company had ongoing clinical trials for
     epilepsy, migraine and stroke. In the first nine months of 1998, the
     Company's clinical efforts were mainly focused on a clinical trial of
     ganaxolone in the treatment of migraine and preclinical development of the
     Company's sodium channel blocker. The narrower focus in the current year
     resulted in lower overall research and development expenses.

     Marketing, general and administrative expense decreased to $1.0 and $3.0
     million in the three and nine-month periods ended September 30, 1998,
     respectively, from $2.9 and $8.4 million in the comparable periods of the
     prior year. Results for the first nine months of 1997 include the costs of
     the sales and marketing division, which was sold in October 1997.

     Gain on disposition of sales division was $750,000 for the nine-month
     period ended September 30, 1998. In April 1998, Watson paid the Company the
     first of two contingent payments based on Watson's ability to retain
     members of the sales and marketing division. The final payment of $250,000
     was made in October 1998 and will be recognized in the fourth quarter.

     Interest income was $261,000 and $695,000 for the three- and nine-month
     periods ended September 30, 1998, respectively, compared to $230,000 and
     $638,000 for the same periods in fiscal 1997. The increase is due to higher
     average cash and investment balances in the current year when compared to
     the same periods a year earlier.

     Preferred dividends were $1.1 million and $1.6 million for the three and
     nine-month periods ended September 30, 1998, respectively, while there were
     no dividends in the comparable periods of the prior fiscal year. Preferred
     dividends arise from the amortization of discounts from the face value of
     outstanding preferred stock and do not involve the payment of cash. Certain
     of the discounts relating to the June 1998 sale of preferred stock will be
     fully amortized as of October 8, 1998; accordingly, the Company anticipates
     that the amount of preferred dividends will decrease in future periods.

     LIQUIDITY AND CAPITAL RESOURCES

     From its inception in February 1989 through September 30, 1998, the Company
     has financed its operations primarily through private and public offerings
     of its equity securities, raising net proceeds of approximately $102.0
     million. At September 30, 1998, the Company's balances of cash, cash
     equivalents and investments totaled $15.6 million, compared to $13.0
     million at December 31, 1997.

     Since its inception in February 1989 through September 30, 1998, the
     Company had invested $7.6 million in leasehold improvements, laboratory and
     computer equipment and office furnishings and equipment. The Company has
     financed $3.6 million of these capital additions through capital lease
     lines. In addition, the Company leases its laboratory and office facilities
     under operating leases. 

                                       13

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

     While additional equipment will be needed as the Company increases its 
     research and development activities, the Company has no material 
     commitments for the acquisition of property and equipment.

     On June 8, 1998, the Company issued 8,000 shares of Series E Convertible
     Preferred Stock with a stated value of $1,000 per share for an aggregate of
     $8 million in a private placement pursuant to Regulation D of the
     Securities Act of 1933, as amended. See Note 8 of the Notes to Condensed
     Financial Statements "Private Placement of Preferred Stock," above.

     Pursuant to an agreement with Watson, in October 1997, the Company sold it
     sales and marketing division, related co-promotion agreements and certain
     other assets to Watson for $8.0 million in cash with an additional $1.0
     million due to CoCensys contingent upon the occurrence of specified events.
     Of this contingent amount, Watson paid the Company $750,000 in April 1998
     and $250,000 in October 1998.

     Pursuant to the 1995 collaboration agreement with Warner-Lambert Company,
     as amended and extended in October 1997, Warner-Lambert is obligated to
     make certain milestone payments for each compound selected for development,
     as well as pay for its share of development costs. Under the terms of the
     1995 agreement, Warner-Lambert purchased $2.0 million of CoCensys Common
     Stock in October 1995 and an additional $2.0 million of CoCensys Common
     Stock in March 1997. Under the terms of the 1997 amendment, Warner-Lambert
     purchased preferred stock with a face value of $7.0 million, of which
     Warner-Lambert paid the Company $1.0 million in October 1997 and $6.0
     million in January 1998. Of this $7.0 million in total proceeds, the
     Company has allocated $1.6 million to be recognized as co-development
     revenue during fiscal 1998, $4.4 million as preferred stock and $1.0
     million as a liability (payable in common stock) due to Warner Lambert in
     January 1999. The preferred stock accrues an imputed non-cash dividend at
     12 percent per annum until its mandatory conversion date in October 2001.

     Pursuant to the May 1997 Development and Commercialization Agreement with
     Wyeth-Ayerst, Wyeth-Ayerst paid the Company a $5.0 million license fee and
     purchased 100,000 shares of the Company's Series C Convertible Preferred
     stock for $5.0 million. Furthermore, Wyeth-Ayerst is obligated to pay all
     development costs associated with Co 2-6749, as well as make milestone
     payments upon the occurrence of certain agreed upon events and pay the
     Company $3.0 million per year for up to three years to identify back-up
     compounds. However, if Co 2-6749 fails to meet certain criteria, and the
     back-up program fails to produce a back-up compound that meets other
     certain criteria, Wyeth-Ayerst has the right to terminate the back-up
     program and require CoCensys to reimburse them for a portion of the back-up
     funding.

     Pursuant to the Company's Development and Commercialization Agreement with
     G.D. Searle & Co., both companies were obligated to pay a portion of the
     development costs of CCD 3693 and its back-up compounds for the U.S.
     market. In addition, Searle purchased 100,000 shares of the Company's
     Series B Convertible Preferred Stock for $7.0 million during 1996. In May
     1998, the preferred stock converted, in accordance with its terms, into 1.6
     million shares of common stock at a conversion price of $4.375 per share.
     In July 1998, Searle notified CoCensys that it had decided not to
     participate further in the development of the Company's proprietary
     compounds for the 


                                       14

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

     treatment of insomnia. CoCensys intends to continue research and 
     development of its compounds to treat insomnia and will consider seeking 
     a new partner for the program in the future.

     CoCensys' operations to date have consumed substantial amounts of cash. The
     negative cash flow from operations is expected to continue and will likely
     increase over the foreseeable future, subject to the Company's ability to
     mitigate such negative cash flows with revenues, if any, derived from
     license fees and milestone payments from research and development
     collaborations for its proprietary products and additional sales of equity.
     The Company anticipates that its existing capital resources, including
     funding expected to be available through current partner collaborations 
     and additional research and development collaborations that will be sought 
     by the Company, will be adequate to satisfy its capital needs for at least 
     the next 12 months.

     The Company will need to obtain substantial additional funds to conduct the
     costly and time-consuming research, preclinical development and clinical
     trials necessary to bring its products to market. The Company intends to
     seek additional funding through additional research and development
     collaborations with suitable corporate partners and/or through public or
     private financing. There can be no assurance that additional financings or
     suitable collaborations will be available on favorable terms, if at all.
     Insufficient funds may require the Company to delay, scale back or
     eliminate some or all of its research and product development programs or
     to license third parties to commercialize products or technologies that the
     Company would otherwise seek to develop itself.

     The Company's future capital requirements will depend on many factors,
     including the progress of the Company's research and development programs,
     the scope and results of preclinical testing and clinical trials, the time
     and costs involved in obtaining regulatory approvals, the rate of
     technological advances, determinations as to the commercial potential of
     the Company's products under development, the status of competitive
     products, the establishment of third-party manufacturing arrangements and
     the establishment of additional collaborative relationships.

     IMPACT OF YEAR 2000

     Some of the Company's older computer programs were written using two digits
     rather than four to define the applicable year. As a result, those computer
     programs recognize a date using "00" as the year 1900 rather than the year
     2000. This could cause a system failure or miscalculations causing
     disruptions of operations, including a temporary inability to process
     transactions or engage in normal business activities.

     The Company has completed a preliminary assessment and will have to modify
     or replace portions of its software and hardware so that its computer
     systems will function properly with respect to dates in the year 2000 and
     thereafter. However, the majority of software and hardware used by the
     Company consists of commercially available, off-the-shelf programs and
     equipment that have already been modified, or are soon to be modified, by
     their manufacturers to handle the year 2000 correctly. As such, management
     believes that the year 2000 issue does not pose a significant problem for
     the Company and it is expected that this project will be completed not
     later than December 31, 1998 at a 

                                       15

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

     total cost of less than $50,000. The Company has incurred minimal costs to 
     date. However, if such modifications and conversions are not made, or are 
     not completed timely, the year 2000 issue could have a material impact on 
     the operations of the Company.

     ADDITIONAL RISKS

     In addition to those discussed above, the Company is subject to the
     following risks:

     The Company's products are in an early stage of development and face a high
     degree of technological, regulatory and competitive risks. Drug discovery
     and development are capital intensive activities, and there can be no
     assurance the Company will be able to raise the additional capital
     necessary to develop and commercialize products. The Company's strategy for
     the development, clinical testing and commercialization of its products
     includes entering into various collaborations with corporate partners,
     licensors, licensees and others. There can be no assurance that the Company
     will be able to negotiate further collaborative arrangements on acceptable
     terms, if at all, or that the current collaborative efforts will be
     continued or successful. Human clinical trials require considerable time
     and funding, and results from any stage of testing may not predict results
     of later stages. In addition, if results of any clinical trial fail to meet
     the Company's requirements, the study plan for such compound may be
     adjusted or another compound may be substituted, either of which may result
     in delays in future clinical studies. Unfavorable clinical trials could
     result in cancellation of future clinical studies. Inherent in the fact
     that CoCensys is an early stage biopharmaceutical company are a range of
     additional risks, including those associated with obtaining and enforcing
     patents and protecting proprietary technology and the risk of regulatory
     change, among others.

     The securities markets have from time to time experienced significant price
     and volume fluctuations that may be unrelated to the operating performance
     of particular companies. The market prices of the common stock of many
     publicly traded biopharmaceutical companies have in the past been, and can
     in the future be expected to be, especially volatile due to various
     external factors, including but not limited to, announcements of
     technological innovations or new products by the Company or its
     competitors, developments or disputes concerning patents or proprietary
     rights, publicity regarding actual or potential results relating to
     products under development, regulatory developments in both the United
     States and foreign countries and public concern as to the safety of
     biotechnology products.

     As of November 5, 1998, 6,455 shares of the Series E Convertible Preferred
     Stock ("Series E Stock") were issued and outstanding. Each share of the
     Series E Stock is convertible into such number of shares of common stock as
     is determined by dividing the stated value ($1,000) of the share of Series
     E Stock (as such value is increased by dividends based on the number of
     days the Series E Stock is held) by the then current conversion price
     (which is determined by reference to the then current market price). If
     converted on November 5, 1998, the Series E Stock would have been
     convertible into approximately 12 million shares of common stock, but this
     number of shares could prove to be significantly greater in the event of a
     decrease in the market price of the common stock which could cause
     substantial dilution of the Company's common stock.


                                       16

<PAGE>

                                 COCENSYS, INC.
                          (A development stage company)

     In order to comply with the rules of the Nasdaq Stock Market, the Company
     is required to obtain the approval of the holders of a majority of its
     common stock (not including shares of common stock issued as a dividend on
     or upon conversion of the Series E Stock) prior to issuing shares of common
     stock as a dividend on or upon conversion of Series E Stock in excess of an
     aggregate of 4,932,948 shares. If such approval is not obtained, the
     Company would be required to redeem the then-outstanding Series E Stock for
     cash in an amount equal to 110% of the aggregate conversion price then in
     effect. The occurrence of certain other events, including certain
     bankruptcy events or delisting of the common stock, also require redemption
     of the Series E Stock. Redemption of the Series E Stock could significantly
     deplete the Company's cash reserves and materially adversely affect its
     operations and financial condition.

     The Company's common stock is traded on the Nasdaq National Market. In
     order to maintain its listing of the Nasdaq National Market, the Company
     must maintain net tangible assets, market capitalization and public float
     at specified levels, and generally must maintain a minimum bid price of
     $1.00 per share. The low bid price for the Company's shares has recently
     included bids below $1.00 per share. The Nasdaq SmallCap Market also
     requires a minimum bid price of $1.00 per share. If the Company is unable
     to maintain continued listing of the common stock on either of these
     markets, its securities could trade on the OTC Bulletin Board or in the
     over-the-counter market in what is commonly referred to as the "pink
     sheets." If this occurs, a stockholder will find it more difficult to
     dispose of the securities or to obtain accurate quotations as to the price
     of the securities. In addition, the common stock could become subject to
     the "penny stock" regulations promulgated under the Exchange Act, which
     impose additional restrictions on broker-dealers who trade in such stock
     and could severely limit the liquidity of the Company's securities. Failure
     to maintain listing on the Nasdaq National Market or Nasdaq SmallCap Market
     also would constitute an event requiring redemption of the Series E Stock.

                                       17
<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

PART II.  OTHER INFORMATION

ITEM 6.   EXHIBITS AND REPORTS ON FORM 8-K

     (a)  Exhibits
<TABLE>
 <S>    <C>                                                <C>

  10.1   1998 Non-Officer Equity Incentive Plan and 
               Form of Agreements                           **

  27     Financial Data Schedule                            **
</TABLE>
- ----------
**   Filed with EDGAR version only.

(b)  Reports on Form 8-K

     The Company filed a Form 8-K on August 5, 1998, reporting under Item 5 that
     G.D. Searle & Co. decided not to participate further in the development of
     CCD 3693, CoCensys' lead compound for the treatment of insomnia.

     The Company filed a Form 8-K on October 23, 1998, reporting under Item 5
     the results of its Phase II clinical trial of ganaxolone for acute
     migraine.

                                       18

<PAGE>


                                 COCENSYS, INC.
                          (A development stage company)

                                   SIGNATURES

Pursuant to the requirements of the Securities and Exchange Act of 1934, the
registrant has duly caused this report to be signed in its behalf by the
undersigned thereunto duly authorized.

                                               CoCensys, Inc.

Date:   November 5, 1998             By:   /s/  F. Richard Nichol, Ph.D.
      ----------------------             ---------------------------------- 
                                              F. Richard Nichol, Ph.D.
                                      President and Chief Executive Officer
                                           (PRINCIPAL EXECUTIVE OFFICER)

Date:   November 5, 1998             By:   /s/  Robert R. Holmen
      ----------------------             ---------------------------------- 
                                               Robert R. Holmen
                                         Acting Chief Financial Officer
                                    (PRINCIPAL FINANCIAL AND ACCOUNTING OFFICER)

                                       19



<PAGE>

                                          
                                                                   EXHIBIT 10.1
                                   COCENSYS, INC.

                       1998 NON-OFFICER EQUITY INCENTIVE PLAN
                                          
           ADOPTED BY THE BOARD OF DIRECTORS EFFECTIVE SEPTEMBER 16, 1998



1.   PURPOSES.

     (a)  The purpose of the Plan is to provide a means by which selected 
Employees and Consultants may be given an opportunity to benefit from 
increases in value of the common stock of the Company ("Common Stock") 
through the granting of (i) Nonstatutory Stock Options, (ii) stock bonuses 
and (iii) rights to purchase restricted stock, all as defined below. 

     (b)  The Company, by means of the Plan, seeks to retain the services of 
persons who are now Employees or Consultants, to secure and retain the 
services of new Employees and Consultants and to provide incentives for such 
persons to exert maximum efforts for the success of the Company and its 
Affiliates.

     (c)  The Company intends that the Stock Awards issued under the Plan 
shall, in the discretion of the Board, be either (i) Nonstatutory Stock 
Options granted pursuant to Section 6 hereof, or (ii) stock bonuses or rights 
to purchase restricted stock granted pursuant to Section 7 hereof.  All 
Options shall be in such form as issued pursuant to Section 6.

2.   DEFINITIONS.

     (a)  "AFFILIATE" means a corporation or other organization or person 
that directly, or indirectly through one or more intermediaries, controls, or 
is controlled by, or is under common control with, the Company, as defined in 
Rule 144 of the Securities Act.

     (b)  "BOARD" means the Board of Directors of the Company.

     (c)  "CODE"" means the Internal Revenue Code of 1986, as amended.

     (d)  "COMMITTEE" means a committee appointed by the Board in accordance 
with subsection 3(c) of the Plan.

     (e)  "COMPANY" means CoCensys, Inc., a Delaware corporation.

     (f)  "CONSULTANT" means any person, including an advisor, engaged by the 
Company or an Affiliate to render consulting services and who is compensated 
for such services, provided that the term "Consultant" shall not include a 
Director.

     (g)  "CONTINUOUS STATUS AS AN EMPLOYEE OR CONSULTANT" means the service 
relationship of a person, whether as an Employee or a Consultant, is not 
interrupted or terminated.  The Board or the Committee, in that party's sole 
discretion, may determine whether Continuous Status as an Employee or 
Consultant shall be considered interrupted in the case of:

                                       1

<PAGE>

(i) any leave of absence approved by the Board, including sick leave, 
military leave, or any other personal leave or (ii) transfers between 
locations of the Company or between the Company, Affiliates or their 
successors.

     (h)  "DIRECTOR" means a member of the Board.

     (i)  "DISABILITY" means that an individual is unable to engage in any 
substantial gainful activity by reason of any medically determinable physical 
or mental impairment which can be expected to result in death or which has 
lasted for a sufficiently long period of time for the individual to be 
eligible under the Company's policy of long-term disability insurance.

     (j)  "EMPLOYEE" means any person employed by the Company or any 
Affiliate of the Company.  Neither service as a Director nor payment of a 
Director's fee by the Company shall be sufficient to constitute "employment" 
by the Company.

     (k)  "EXCHANGE ACT" means the Securities Exchange Act of 1934, as 
amended.

     (l)  "FAIR MARKET VALUE" means, as of any date, the value of the Common 
Stock of the Company determined as follows:

          (1)  If the Common Stock is listed on any established stock 
exchange or traded on the Nasdaq National Market or The Nasdaq SmallCap 
Market, the Fair Market Value of a Share shall be the closing sales price for 
such Share (or the closing bid, if no sales were reported) as quoted on such 
exchange or market (or the exchange or market with the greatest volume of 
trading in the Common Stock) on the last market trading day prior to the day 
of determination, as reported in THE WALL STREET JOURNAL or such other source 
as the Board deems reliable.

          (2)  In the absence of such markets for the Common Stock, the Fair 
Market Value shall be determined in good faith by the Board.

     (m)  "NONSTATUTORY STOCK OPTION" means an Option not intended to qualify 
as an incentive stock option pursuant to Section 422 of the Code and the 
regulations promulgated thereunder.

     (n)  "OFFICER" means an Employee of the Company who holds the position 
of vice president or a more senior position or is an "executive officer" of 
the Company as defined in Section 16 of the Exchange Act.

     (0)  "OPTION" means a Nonstatutory Stock Option granted pursuant to the 
Plan.

     (p)  "OPTION AGREEMENT" means a written agreement between the Company 
and an Option Holder evidencing the terms and conditions of an individual 
Option grant.  Each Option Agreement shall be subject to the terms and 
conditions of the Plan.

     (q)  "OPTION HOLDER" means a person to whom an Option is granted 
pursuant to the Plan.

     (r)  "PLAN" means this CoCensys, Inc. 1998 Non-Officer Equity Incentive 
Plan.

                                      2

<PAGE>

     (s)  "SHARE" means a share of Common Stock of the Company.

     (t)  "STOCK AWARD" means any right granted under the Plan, including any 
Option, any stock bonus and any right to purchase restricted stock. 

     (u)  "SECURITIES ACT" means the Securities Act of 1933, as amended.

     (v)  "STOCK AWARD AGREEMENT" means a written agreement between the 
Company and a holder of a Stock Award evidencing the terms and conditions of 
an individual Stock Award grant.  Each Stock Award Agreement shall be subject 
to the terms and conditions of the Plan.

3.   ADMINISTRATION.

     (a)  The Plan shall be administered by the Board unless and until the 
Board delegates administration to a Committee, as provided in subsection 3(c).

     (b)  The Board shall have the power, subject to, and within the 
limitations of, the express provisions of the Plan:

          (1)  To determine from time to time which of the persons eligible 
under the Plan shall be granted Stock Awards; when and how each Stock Award 
shall be granted; whether a Stock Award will be an Option, a stock bonus, a 
right to purchase restricted stock, or a combination of the foregoing; the 
provisions of each Stock Award granted (which need not be identical), 
including the time or times when a person shall be permitted to receive 
Shares pursuant to a Stock Award and the number of Shares with respect to 
which a Stock Award shall be granted to each such person.

          (2)  To construe and interpret the Plan and Stock Awards granted 
under it, and to establish, amend and revoke rules and regulations for its 
administration.  The Board, in the exercise of this power, may correct any 
defect, omission or inconsistency in the Plan or in any Stock Award 
Agreement, in a manner and to the extent it shall deem necessary or expedient 
to make the Plan fully effective.

          (3)  To amend the Plan or a Stock Award as provided in Section 12.

          (4)  Generally, to exercise such powers and to perform such acts as 
the Board deems necessary or expedient to promote the best interests of the 
Company which are not in conflict with the provisions of the Plan.

     (c)  The Board may delegate administration of the Plan to a committee or 
committees ("Committee") of one or more members of the Board.  If 
administration is delegated to a Committee, the Committee shall have, in 
connection with the administration of the Plan, the powers theretofore 
possessed by the Board (and references in this Plan to the Board shall 
thereafter be to the Committee), subject, however, to such resolutions, not 
inconsistent with the provisions of the Plan, as may be adopted from time to 
time by the Board.  The Board may abolish the Committee at any time and 
revest in the Board the administration of the Plan.

                                       3

<PAGE>

4.   SHARES SUBJECT TO THE PLAN.

     (a)  Subject to the provisions of Section 11 relating to adjustments 
upon changes in the Common Stock, the Shares that may be issued pursuant to 
Stock Awards shall not exceed in the aggregate two million (2,000,000) 
Shares.  If any Stock Award shall for any reason expire or otherwise 
terminate, in whole or in part, without having been exercised in full (or 
vested in the case of restricted stock), the Shares not acquired under such 
Stock Award shall revert to and again become available for issuance under the 
Plan.

     (b)  The Shares subject to the Plan may be unissued Shares or reacquired 
Shares bought on the market or otherwise.

5.   ELIGIBILITY.

     Stock Awards may be granted only to Employees or Consultants who are 
not, at the time of such grants, either (i) Directors or (ii) Officers.

6.   OPTION PROVISIONS.

     Each Option shall be in such form and shall contain such terms and 
conditions as the Board shall deem appropriate.  The provisions of separate 
Options need not be identical, but each Option shall include (through 
incorporation of provisions hereof by reference in the Option or otherwise) 
the substance of each of the following provisions:

     (a)  TERM.  No Option shall be exercisable after the expiration of ten 
(10) years from the date it was granted or such longer or shorter term as may 
be provided in the Option Agreement.

     (b)  PRICE.  The exercise price of each Option shall be as determined by 
the Board and shall be set forth in the Option Agreement.

     (c)  CONSIDERATION.  The consideration to be paid for the Shares to be 
issued upon exercise of an Option, including the method of payment, shall be 
determined by the Board and may consist entirely of (i) cash or check, (ii) 
promissory note (except that payment of the Share's "par value", as defined 
in the Delaware General Corporation Law, shall not be made by deferred 
payment), (iii) other Shares having a fair market value on the date of 
surrender equal to the aggregate exercise price of the Shares as to which the 
Option shall be exercised, including by delivering to the Company an 
attestation of ownership of owned and unencumbered Shares in a form approved 
by the Company, (iv) payment pursuant to a program developed under Regulation 
T as promulgated by the Federal Reserve Board which, prior to the issuance of 
the Shares, results in either the receipt of cash (or check) by the Company 
or the receipt of irrevocable instructions to pay the aggregate exercise 
price to the Company from the sales proceeds, (v) any combination of such 
methods of payment or (vi) such other consideration and method of payment for 
the issuance of Shares to the extent permitted under applicable law.  In 
making its determination as to the type of consideration to accept, the Board 
shall consider if acceptance of such consideration may be reasonably expected 
to benefit the Company.  In the case of any deferred payment arrangement, 
interest shall be charged at the minimum rate of

                                       4

<PAGE>

interest necessary to avoid the treatment as interest, under any applicable 
provisions of the Code, of any amounts other than amounts stated to be 
interest under the deferred payment arrangement.

     (d)  TRANSFERABILITY.  An Option may be transferred to the extent 
provided in the Option Agreement; provided that if the Option Agreement does 
not expressly permit the transfer of an Option, the Option shall not be 
transferable except by will or by the laws of descent and distribution and 
shall be exercisable during the lifetime of the person to whom the Option is 
granted only by such person.  Notwithstanding the foregoing, the person to 
whom the Option is granted may, by delivering written notice to the Company, 
in a form satisfactory to the Company, designate a third party who, in the 
event of the death of the Option Holder, shall thereafter be entitled to 
exercise the Option.

     (e)  VESTING.  The total number of Shares subject to an Option may, but 
need not, be allotted in periodic installments (which may, but need not, be 
equal).  The Option Agreement may provide that from time to time during each 
of such installment periods, the Option may become exercisable ("vest") with 
respect to some or all of the Shares allotted to that period, and may be 
exercised with respect to some or all of the Shares allotted to such period 
and/or any prior period as to which the Option became vested but was not 
fully exercised.  The Option may be subject to such other terms and 
conditions on the time or times when it may be exercised (which may be based 
on performance or other criteria) as the Board may deem appropriate.  The 
vesting provisions of individual Options may vary.  The provisions of this 
subsection 6(e) are subject to any Option provisions governing the minimum 
number of Shares as to which an Option may be exercised.

     (f)  TERMINATION OF EMPLOYMENT OR CONSULTING RELATIONSHIP.

          (1)  If an Option Holder's Continuous Status as an Employee or 
Consultant terminates (other than upon the Option Holder's death or 
disability), the Option Holder may exercise his or her Option within such 
period of time designated by the Board, which shall in no event be later than 
the expiration of the term of the Option as set forth in the Option Agreement 
(the "Post-Termination Exercise Period") and only to the extent that the 
Option Holder was entitled to exercise the Option on the date the Option 
Holder's Continuous Status as an Employee or Consultant terminates.  The 
Board may at any time extend the Post-Termination Exercise Period and provide 
for continued vesting during such extended period.  If, as of the date of 
termination, the Option Holder is not entitled to exercise his or her entire 
Option, the Shares covered by the unexercisable portion of the Option shall 
revert to the Plan.  If, after termination, the Option Holder does not 
exercise his or her Option within the time specified in the Option Agreement 
or as otherwise determined above, the Option shall terminate, and the Shares 
covered by such Option shall revert to the Plan.  Notwithstanding the 
foregoing, the Board shall have the power to permit an Option to vest, in 
whole or in part, during the Post-Termination Exercise Period.

          (2)  An Option Holder's Option Agreement may also provide that if 
the exercise of the Option following the termination of the Option Holder's 
Continuous Status as an Employee or Consultant (other than upon the Option 
Holder's death or disability) would be prohibited at any time solely because 
the issuance of Shares would violate the registration requirements under the 
Securities Act, then the Option shall terminate on the earlier of (i) the 

                                      5

<PAGE>

expiration of the term of the Option set forth in the first paragraph of this 
subsection 6(f), or (ii) the expiration of a period of three (3) months after 
the termination of the Option Holder's Continuous Status as an Employee or 
Consultant during which the exercise of the Option would not be in violation 
of such registration requirements.

     (g)  DISABILITY OF OPTION HOLDER.  If an Option Holder's Continuous 
Status as an Employee or Consultant terminates as a result of the Option 
Holder's Disability, the Option Holder may exercise his or her Option (to the 
extent that the Option Holder was entitled to exercise it as of the date of 
termination), but only within such period of time ending on the earlier of 
(i) the date twelve (12) months following such termination (or such longer or 
shorter period specified in the Option Agreement), or (ii) the expiration of 
the term of the Option as set forth in the Option Agreement.  If, at the date 
of termination, the Option Holder is not entitled to exercise his or her 
entire Option, the Shares covered by the unexercisable portion of the Option 
shall revert to and again become available for issuance under the Plan.  If, 
after termination, the Option Holder does not exercise his or her Option 
within the time specified herein, the Option shall terminate, and the Shares 
covered by such Option shall revert to and again become available for 
issuance under the Plan.

     (h)  DEATH OF OPTION HOLDER.  In the event of the death of an Option 
Holder during, or within a period specified in the Option Agreement after the 
termination of, the Option Holder's Continuous Status as an Employee or 
Consultant, the Option may be exercised (to the extent the Option Holder was 
entitled to exercise the Option as of the date of death) by the Option 
Holder's estate, by a person who acquired the right to exercise the Option by 
bequest or inheritance, but only within the period ending on the earlier of 
(i) the date twelve (12) months following the date of death (or such longer 
or shorter period specified in the Option Agreement), or (ii) the expiration 
of the term of such Option as set forth in the Option Agreement.  If, at the 
time of death, the Option Holder was not entitled to exercise his or her 
entire Option, the Shares covered by the unexercisable portion of the Option 
shall revert to and again become available for issuance under the Plan.  If, 
after death, the Option is not exercised within the time specified herein, 
the Option shall terminate, and the Shares covered by such Option shall 
revert to and again become available for issuance under the Plan.

     (i)  EARLY EXERCISE.  The Option may, but need not, include a provision 
whereby the Option Holder may elect at any time while an Employee or 
Consultant to exercise the Option as to any part or all of the Shares subject 
to the Option prior to the full vesting of the Option.  Any unvested Shares 
so purchased may be subject to a repurchase right in favor of the Company or 
to any other restriction the Board determines to be appropriate.

     (j)  RE-LOAD OPTIONS.

          (1)  Without in any way limiting the authority of the Board to make 
or not to make grants of Options hereunder, the Board shall have the 
authority (but not an obligation) to include as part of any Option Agreement 
a provision entitling the Option Holder to a further Option (a "Re-Load 
Option") if the Option Holder exercises the Option evidenced by the Option 
Agreement, in whole or in part, by surrendering other Shares in accordance 
with this Plan and the terms and conditions of the Option Agreement.  Any 
such Re-Load Option (i) shall be for a number of Shares equal to the number 
of Shares surrendered as part or all of the exercise price of

                                      6

<PAGE>

such Option, (ii) shall have an expiration date which is the same as the 
expiration date of the Option the exercise of which gave rise to such Re-Load 
Option and (iii) shall have an exercise price which is equal to one hundred 
percent (100%) of the Fair Market Value of the Shares subject to the Re-Load 
Option on the date of exercise of the original Option.

          (2)  There shall be no Re-Load Options on a Re-Load Option.  Any 
such Re-Load Option shall be subject to the availability of sufficient Shares 
under subsection 4(a) and shall be subject to such other terms and conditions 
as the Board may determine which are not inconsistent with the express 
provisions of the Plan regarding the terms of Options.

7.   TERMS OF STOCK BONUSES AND PURCHASES OF RESTRICTED STOCK.

     Each stock bonus or restricted stock purchase agreement shall be in such 
form and shall contain such terms and conditions as the Board shall deem 
appropriate.  The terms and conditions of stock bonus or restricted stock 
purchase agreements may change from time to time, and the terms and 
conditions of separate agreements need not be identical, but each stock bonus 
or restricted stock purchase agreement shall include (through incorporation 
of provisions hereof by reference in the agreement or otherwise) the 
substance of each of the following provisions as appropriate:

     (a)  PURCHASE PRICE.  The purchase price under each restricted stock 
purchase agreement shall be such amount as the Board shall determine and 
designate in such agreement.  Notwithstanding the foregoing, the Board may 
determine that eligible participants in the Plan may be awarded stock 
pursuant to a stock bonus agreement in consideration for past services 
actually rendered to the Company or for its benefit.

     (b)  TRANSFERABILITY.  No rights under a stock bonus or restricted stock 
purchase agreement shall be transferable except by will or the laws of 
descent and distribution so long as stock awarded under such agreement 
remains subject to the terms of any restrictive covenant (such as a 
repurchase option or reacquisition option) in favor of the Company.

     (c)  CONSIDERATION.  The purchase price of Shares acquired pursuant to a 
stock purchase agreement shall be paid either:  (i) in cash or by check at 
the time of purchase, (ii) at the discretion of the Board, according to a 
deferred payment documented by use of a promissory note or other arrangement 
with the person to whom the Shares are sold on such terms approved by the 
Board, except that payment of the common stock's "par value" (as defined in 
the Delaware General Corporation Law) shall not be made by deferred payment, 
or (iii) in any other form of legal consideration that may be acceptable to 
the Board in its discretion.  Notwithstanding the foregoing, the Board may 
award stock pursuant to a stock bonus agreement in consideration for past 
services actually rendered to the Company or for its benefit.

     (d)  VESTING.  Shares sold or awarded under the Plan may, but need not, 
be subject to a repurchase option or reacquisition option in favor of the 
Company in accordance with a vesting schedule to be determined by the Board.

     (e)  TERMINATION OF CONTINUOUS STATUS AS AN EMPLOYEE OR CONSULTANT.  If 
a Participant's Continuous Status as an Employee or Consultant terminates, 
the Company may repurchase or otherwise reacquire any or all of the Shares 
held by that person which have not

                                       7

<PAGE>

vested as of the date of termination under the terms of the stock bonus or 
restricted stock purchase agreement between the Company and such person.

8.   CANCELLATION AND RE-GRANT OF OPTIONS.

     The Board shall have the authority to effect, at any time and from time 
to time, (i) the repricing of any outstanding Options under the Plan and/or 
(ii) with the consent of any adversely affected holders of Options, the 
cancellation of any outstanding Options under the Plan and the grant in 
substitution therefor of new Options under the Plan covering the same or 
different numbers of Shares.

9.   COVENANTS OF THE COMPANY.

     (a)  During the terms of the Stock Awards, the Company shall keep 
available at all times the number of Shares required to satisfy such Stock 
Awards.

     (b)  The Company shall seek to obtain from each regulatory commission or 
agency having jurisdiction over the Plan such authority as may be required to 
issue and sell Shares under Stock Awards; provided, however, that this 
undertaking shall not require the Company to register under the Securities 
Act either the Plan, any Stock Award or any Shares issued or issuable 
pursuant to any such Stock Award.  If, after reasonable efforts, the Company 
is unable to obtain from any such regulatory commission or agency the 
authority which counsel for the Company deems necessary for the lawful 
issuance and sale of Shares under the Plan, the Company shall be relieved 
from any liability for failure to issue and sell Shares upon exercise of such 
Stock Awards unless and until such authority is obtained.

10.  USE OF PROCEEDS FROM SHARES.

     Proceeds from the sale of Shares pursuant to Stock Awards shall 
constitute general funds of the Company.

11.  MISCELLANEOUS.

     (a)  The Board shall have the power to accelerate the time at which all 
or any part of a Stock Award may first be exercised or the time during which 
a Stock Award or any part thereof will vest, notwithstanding the provisions 
in the Stock Award stating the time at which it may first be exercised or the 
time during which it will vest.

     (b)  No Employee, Consultant or any person to whom a Stock Award is 
transferred in accordance with the Plan shall be deemed to be the holder of, 
or to have any of the rights of a holder with respect to, any Shares subject 
to such Stock Award unless and until such person has satisfied all 
requirements for exercise of the Stock Award pursuant to its terms.

     (c)  Nothing in the Plan or any instrument executed or Stock Award 
granted pursuant thereto shall confer upon any Employee, Consultant or other 
holder of Stock Awards any right to continue in the employ of the Company or 
any Affiliate or to continue serving as a Consultant or shall affect the 
right of the Company or any Affiliate to terminate the employment of any 
Employee with or without notice and with or without cause, or the right to 
terminate the

                                      8

<PAGE>

relationship of any Consultant pursuant to the terms of such Consultant's 
agreement with the Company or Affiliate.

     (d)  The Company may require any person to whom a Stock Award is 
granted, or any person to whom a Stock Award is transferred in accordance 
with the Plan, as a condition of exercising or acquiring Shares under any 
Stock Award, (i) to give written assurances satisfactory to the Company as to 
such person's knowledge and experience in financial and business matters 
and/or to employ a purchaser representative reasonably satisfactory to the 
Company who is knowledgeable and experienced in financial and business 
matters, and that he or she is capable of evaluating, alone or together with 
the purchaser representative, the merits and risks associated with the Stock 
Award, and (ii) to give written assurances satisfactory to the Company 
stating that such person is acquiring the Shares subject to the Stock Award 
for such person's own account and not with any present intention of selling 
or otherwise distributing the Shares.  The foregoing requirements, and any 
assurances given pursuant to such requirements, shall be inoperative if (1) 
the issuance of the Shares upon the exercise or acquisition of Shares under 
the Stock Award has been registered under a then currently effective 
registration statement under the Securities Act, or (2) as to any particular 
requirement, a determination is made by counsel for the Company that such 
requirement need not be met in the circumstances under the then applicable 
securities laws.  The Company may, upon advice of counsel to the Company, 
place legends on stock certificates issued under the Plan as such counsel 
deems necessary or appropriate in order to comply with applicable securities 
laws, including, but not limited to, legends restricting the transfer of the 
Shares.

     (e)  To the extent provided by the terms of a Stock Award Agreement, the 
person to whom a Stock Award is granted may satisfy any federal, state or 
local tax withholding obligation relating to the exercise or acquisition of 
Shares under a Stock Award by any of the following means or by a combination 
of such means:  (i) tendering a cash payment, (ii) authorizing the Company to 
withhold Shares from the Shares otherwise issuable to the participant as a 
result of the exercise or acquisition of Shares under the Stock Award or 
(iii) delivering to the Company owned and unencumbered Shares, including by 
delivering to the Company an attestation of ownership of owned and 
unencumbered Shares in a form approved by the Company.

12.  ADJUSTMENTS UPON CHANGES IN STOCK.

     (a)  If any change is made in the Shares subject to the Plan, or subject 
to any Stock Award, without the receipt of consideration by the Company 
(through merger, consolidation, reorganization, recapitalization, 
reincorporation, stock dividend, dividend in property other than cash, stock 
split, liquidating dividend, combination of Shares, exchange of Shares, 
change in corporate structure or other transaction not involving the receipt 
of consideration by the Company), the Plan will be appropriately adjusted in 
the class(es) and maximum number of Shares subject to the Plan pursuant to 
subsection 4(a), and the outstanding Stock Awards will be appropriately 
adjusted in the class(es) and number of Shares and price per Share subject to 
such outstanding Stock Awards. Such adjustments shall be made by the Board, 
the determination of which shall be final, binding and conclusive.  (The 
conversion of any convertible securities of the Company shall not be treated 
as a "transaction not involving the receipt of consideration by the Company".)

                                       9

<PAGE>

     (b)  In the event of:  (1) a dissolution, liquidation, or sale of all or 
substantially all of the assets of the Company, (2) a merger or consolidation 
in which the Company is not the surviving corporation, (3) a reverse merger 
in which the Company is the surviving corporation but Shares outstanding 
immediately preceding the merger are converted by virtue of the merger into 
other property, whether in the form of securities, cash or otherwise, then to 
the extent permitted by applicable law:  (i) any surviving corporation (or an 
Affiliate thereof) shall assume any Stock Awards outstanding under the Plan 
or shall substitute similar Stock Awards for those outstanding under the 
Plan, or (ii) such Stock Awards shall continue in full force and effect.  If 
any surviving corporation (or Affiliate) refuses to assume such Stock Awards, 
or to substitute similar Stock Awards for those outstanding under the Plan, 
then with respect to Stock Awards held by persons then performing services as 
Employees or Consultants, the time during which such Stock Awards may be 
exercised shall be accelerated to allow the Option Holders a reasonable 
amount of time to exercise all Shares covered by such Stock Award and the 
Stock Awards terminated if not exercised during such time.

13.  AMENDMENT OF THE PLAN AND STOCK AWARDS.

     (a)  The Board at any time, and from time to time, may amend the Plan.

     (b)  The Board, in its sole discretion, may submit the Plan and/or any 
amendment to the Plan for stockholder approval.

     (c)  Rights and obligations under any Stock Award granted before 
amendment of the Plan shall not be impaired by any amendment of the Plan 
unless (i) the Company requests the consent of the person to whom the Stock 
Award was granted and (ii) such person consents in writing.

     (d)  The Board at any time, and from time to time, may amend the terms 
of any one or more Stock Awards; provided, however, that the rights and 
obligations under any Stock Award shall not be impaired by any such amendment 
unless (i) the Company requests the consent of the person to whom the Stock 
Award was granted and (ii) such person consents in writing.

14.  TERMINATION OR SUSPENSION OF THE PLAN.

     (a)  The Board may suspend or terminate the Plan at any time.  Unless 
sooner terminated, the Plan shall terminate when all Shares reserved for 
issuance under the Plan have been issued and all such issued Shares are no 
longer subject to a repurchase option or a reacquisition option in favor of 
the Company.  No Stock Awards may be granted under the Plan while the Plan is 
suspended or after it is terminated.

     (b)  Rights and obligations under any Stock Award granted while the Plan 
is in effect shall not be impaired by suspension or termination of the Plan, 
except with the written consent of the person to whom the Stock Award was 
granted.

15.  EFFECTIVE DATE OF PLAN.

     The Plan shall become effective on September 16, 1998.

                                        10

<PAGE>
                                          
                             NONSTATUTORY STOCK OPTION
                                          
                       1998 NON-OFFICER EQUITY INCENTIVE PLAN

__________________________, Optionholder:

     CoCensys, Inc. (the "Company"), pursuant to its 1998 Non-Officer Equity 
Incentive Plan (the "Plan"), has granted to you, the optionholder named 
above, an option to purchase shares of the common stock of the Company 
("Common Stock").  This option is NOT intended to qualify as an "incentive 
stock option" within the meaning of Section 422 of the Internal Revenue Code 
of 1986, as amended (the "Code").

     The grant hereunder is in connection with and in furtherance of the 
Company's compensatory benefit plan for participation of the Company's 
employees or consultants.  Defined terms not explicitly defined in this 
agreement but defined in the Plan shall have the same definitions as in the 
Plan.

     The details of your option are as follows:

     1.   TOTAL NUMBER OF SHARES SUBJECT TO THIS OPTION.  The total number of
shares of Common Stock subject to this option is ____________________ (______).

     2.   VESTING.  Subject to the limitations contained herein, [25%] of the 
shares will vest (become exercisable) on ____________, ____ and the remaining 
[_____________] shares will vest in [thirty-six (36)] equal monthly 
installments thereafter until either (i) you cease to provide services to the 
Company for any reason, or (ii) this option becomes fully vested.

     3.   EXERCISE PRICE AND METHOD OF PAYMENT.

          (a)  EXERCISE PRICE.  The exercise price of this option is 
_________________ ($____) per share, being not less than eighty-five percent 
(85%) of the fair market value of the Common Stock on the date of grant of 
this option.

          (b)  METHOD OF PAYMENT.  Payment of the exercise price per share is 
due in full upon exercise of all or any part of each installment which has 
accrued to you.  You may elect, to the extent permitted by applicable 
statutes and regulations, to make payment of the exercise price under one of 
the following alternatives:

                    (i)   Payment of the exercise price per share in cash 
(including check) at the time of exercise;

                   (ii)   Payment pursuant to a program developed under 
Regulation T as promulgated by the Federal Reserve Board which, prior to the 
issuance of Common Stock, results in either the receipt of cash (or check) by 
the Company or the receipt of irrevocable instructions to pay the aggregate 
exercise price to the Company from the sales proceeds;

                                     11

<PAGE>

                  (iii)   Provided that at the time of exercise the Company's 
Common Stock is publicly traded and quoted regularly in the Wall Street 
Journal, payment by delivery of already-owned shares of Common Stock, held 
for the period required to avoid a charge to the Company's reported earnings, 
and owned free and clear of any liens, claims, encumbrances or security 
interests, which Common Stock shall be valued at its fair market value on the 
date of exercise; or

                   (iv)   Payment by a combination of the methods of payment 
permitted by subparagraph 3(b)(i) through 3(b)(iii) above.

     4.   WHOLE SHARES.  This option may only be exercised for whole shares.

     5.   SECURITIES LAW COMPLIANCE.  Notwithstanding anything to the 
contrary contained herein, this option may not be exercised unless the shares 
issuable upon exercise of this option are then registered under the 
Securities Act or, if such shares are not then so registered, the Company has 
determined that such exercise and issuance would be exempt from the 
registration requirements of the Securities Act.

     6.   TERM.  The term of this option commences on ____________, ____, the 
date of grant, and expires on _________________ (the "Expiration Date"), 
which date shall be no more than ten (10) years from date this option is 
granted, unless this option expires sooner as set forth below or in the Plan. 
 In no event may this option be exercised on or after the Expiration Date.  
This option shall terminate prior to the Expiration Date as follows:  three 
(3) months after the termination of your Continuous Status as an Employee or 
Consultant with the Company or an Affiliate of the Company unless one of the 
following circumstances exists:

          (a)  Your termination of Continuous Status as an Employee or 
Consultant is due to your disability.  This option will then expire on the 
earlier of the Expiration Date set forth above or twelve (12) months 
following such termination of Continuous Status as an Employee or Consultant.

          (b)  Your termination of Continuous Status as an Employee or 
Consultant is due to your death or your death occurs within three (3) months 
following your termination of Continuous Status as an Employee or Consultant 
for any other reason.  This option will then expire on the earlier of the 
Expiration Date set forth above or twelve (12) months after your death.

          (c)  If during any part of such three (3)-month period you may not 
exercise your option solely because of the condition set forth in paragraph 5 
above, then your option will not expire until the earlier of the Expiration 
Date set forth above or until this option shall have been exercisable for an 
aggregate period of three (3) months after your termination of Continuous 
Status as an Employee or Consultant.

          (d)  If your exercise of the option within three (3) months after 
termination of your Continuous Status as an Employee or Consultant with the 
Company or with an Affiliate of the Company would result in liability under 
section 16(b) of the Securities Exchange Act of 1934, then your option will 
expire on the earlier of (i) the Expiration Date set forth above, (ii) the 
tenth (10th) day after the last date upon which exercise would result in such 
liability or (iii) six

                                      12

<PAGE>

(6) months and ten (10) days after the termination of your Continuous Status 
as an Employee or Consultant with the Company or an Affiliate of the Company.

     However, this option may be exercised following termination of 
Continuous Status as an Employee or Consultant only as to that number of 
shares as to which it was exercisable on the date of termination of 
Continuous Status as an Employee or Consultant under the provisions of 
paragraph 2 of this option.

     7.   EXERCISE.

          (a)  This option may be exercised, to the extent specified above, 
by delivering a notice of exercise (in a form designated by the Company) 
together with the exercise price to the Secretary of the Company, or to such 
other person as the Company may designate, during regular business hours, 
together with such additional documents as the Company may then require 
pursuant to subsection 11(d) of the Plan.

          (b)  By exercising this option you agree that, as a precondition to 
the completion of any exercise, the Company may require you to enter an 
arrangement providing for the payment by you to the Company of any tax 
withholding obligation of the Company arising by reason of (1) the exercise 
of this option; (2) the lapse of any substantial risk of forfeiture to which 
the shares are subject at the time of exercise; or (3) the disposition of 
shares acquired upon such exercise.  You also agree that the exercise of this 
option has not been completed and that the Company is under no obligation to 
issue any shares of Common Stock to you until such an arrangement is 
established or the Company's tax withholding obligations are satisfied, as 
determined by the Company.

     8.   TRANSFERABILITY.  This option is not transferable, except by will 
or by the laws of descent and distribution, and is exercisable during your 
life only by you.  Notwithstanding the foregoing, by delivering written 
notice to the Company, in a form satisfactory to the Company, you may 
designate a third party who, in the event of your death, shall thereafter be 
entitled to exercise this option.

     9.   OPTION NOT A SERVICE CONTRACT.  This option is not an employment 
contract and nothing in this option shall be deemed to create in any way 
whatsoever any obligation on your part to continue in the employ of the 
Company, or of the Company to continue your employment with the Company.  In 
addition, nothing in this option shall obligate the Company or any Affiliate 
of the Company, or officers or employees to continue any relationship which 
you might have as a Consultant for the Company or Affiliate of the Company.

     10.  NOTICES.  Any notices provided for in this option or the Plan shall 
be given in writing and shall be deemed effectively given upon receipt or, in 
the case of notices delivered by the Company to you, five (5) days after 
deposit in the United States mail, postage prepaid, addressed to you at the 
address specified below or at such other address as you hereafter designate 
by written notice to the Company.

     11.  GOVERNING PLAN DOCUMENT.  This option is subject to all the 
provisions of the Plan, a copy of which is attached hereto and its provisions 
are hereby made a part of this option, including without limitation the 
provisions of Section 6 of the Plan relating to option provisions,

                                     13

<PAGE>

and is further subject to all interpretations, amendments, rules and 
regulations which may from time to time be promulgated and adopted pursuant 
to the Plan.  In the event of any conflict between the provisions of this 
option and those of the Plan, the provisions of the Plan shall control.

     Dated                     ,         .
           --------------------  --------

                              
                              Very truly yours,

                              COCENSYS, INC.


                              Signed:                            
                                     -----------------------------
                                     Duly authorized on behalf 
                                     of the Board of Directors


                                          
                           ACKNOWLEDGEMENT AND AGREEMENT

The undersigned optionholder:

     (a)  Acknowledges receipt of the foregoing option and the attachments 
referenced therein and understands that all rights and liabilities with 
respect to this option are set forth in the option and the Plan; and

     (b)  Acknowledges that as of the date of grant of this option, it sets 
forth the entire understanding between the undersigned option holder and the 
Company and its Affiliates regarding the acquisition of stock in the Company 
under this option and supersedes and terminates all prior oral and written 
agreements on that subject.


                              ------------------------------------
                              OPTIONHOLDER

                              Address:                            
                                      ----------------------------
                              ------------------------------------


                                     14


<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
COMPANY'S FORM 10-Q FOR THE PERIOD ENDED SEPTEMBER 30, 1998, AND IS QUALIFIED IN
ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                          DEC-31-1998
<PERIOD-START>                             JAN-01-1998
<PERIOD-END>                               SEP-30-1998
<CASH>                                           4,246
<SECURITIES>                                    10,827
<RECEIVABLES>                                       14
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                15,435
<PP&E>                                           6,813
<DEPRECIATION>                                 (4,216)
<TOTAL-ASSETS>                                  18,681
<CURRENT-LIABILITIES>                            6,672
<BONDS>                                            359
                                0
                                     16,664
<COMMON>                                       106,667
<OTHER-SE>                                   (112,209)
<TOTAL-LIABILITY-AND-EQUITY>                    18,681
<SALES>                                              0
<TOTAL-REVENUES>                                 1,886
<CGS>                                                0
<TOTAL-COSTS>                                        0
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                (64)
<INCOME-PRETAX>                               (11,583)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                           (11,583)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                  (11,583)
<EPS-PRIMARY>                                    (.55)
<EPS-DILUTED>                                    (.55)
        

</TABLE>


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission