ENTREMED INC
SC 13D, 1999-01-29
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13D
                                 (Rule 13d-101)


                    INFORMATION TO BE INCLUDED IN STATEMENTS
                 FILED PURSUANT TO RULE 13d-1(a) AND AMENDMENTS
                     THERETO FILED PURSUANT TO RULE 13d-2(a)
                               (Amendment No.  )1

                                 ENTREMED, INC.
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                                (Name of Issuer)

                    COMMON STOCK, PAR VALUE $0.01 PER SHARE
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                         (Title of Class of Securities)

                                   29382F103
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                                 (CUSIP Number)

                GEORGE R. WHITTEMORE, MILLS VALUE ADVISER, INC.,
         707 EAST MAIN STREET, RICHMOND, VIRGINIA 23219 (804) 344-3804
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          (Name, Address and Telephone Number of Person Authorized to
                      Receive Notices and Communications)

                                January 11, 1999
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            (Date of Event which Requires Filing of this Statement)

         If the filing person has  previously  filed a statement on Schedule 13G
to report the  acquisition  that is the  subject of this  Schedule  13D,  and is
filing this schedule because of Rule 13d-1(e),  13d-1(f) or 13d-1(g),  check the
following box |_|.

         Note:  Schedules  filed in paper format shall include a signed original
and five copies of the schedule,  including all exhibits.  See Rule 13d-7(b) for
other parties to whom copies are to be sent.


                         (Continued on following pages)

                               (Page 1 of 6 Pages)




         1 The remainder  of this cover page shall be filled out for a reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.

         The information  required on the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934, as amended (the "Act"),  or otherwise subject to the liabilities of
that section of the Act but shall be subject to all other  provisions of the Act
(however, see the Notes).

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<PAGE>


- ----------------------------                        ----------------------------
    CUSIP No. 29382F103           SCHEDULE 13D            Page 2 of 6 Pages
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1        NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

         James T. Martin
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2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a)    |_|
                                                                      (b)    |_|
         Not Applicable
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3        SEC USE ONLY


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4        SOURCE OF FUNDS*

         PF
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5        CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
         ITEM 2(d) or 2(e)                                                   |_|

         Not Applicable
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6        CITIZENSHIP OR PLACE OF ORGANIZATION

         Bermuda
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       NUMBER OF           7        SOLE VOTING POWER

        SHARES                      625,090
                         -------------------------------------------------------
                           8        SHARED VOTING POWER
     BENEFICIALLY
                                    -0-
                         -------------------------------------------------------
     OWNED BY EACH         9        SOLE DISPOSITIVE POWER

       REPORTING                    625,090
                         -------------------------------------------------------
                           10       SHARED DISPOSITIVE POWER
     PERSON WITH
                                    -0-
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11       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         625,090
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12       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*
                                                                             |_|
         Not Applicable

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13       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         5.0%
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14       TYPE OF REPORTING PERSON*

         IN
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                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>

                                  SCHEDULE 13D
                                       FOR
                                 JAMES T. MARTIN


Item 1.       Security and Issuer

              This  statement  relates to the common stock,  par value $0.01 per
              share ("Common  Stock"),  of EntreMed,  Inc.,  9610 Medical Center
              Drive, Suite 200, Rockville, Maryland 20850 (the "Issuer").


Item 2.       Identity and Background

              (A)     James T. Martin

              (B)     Tuppeny House
                      Tuckerstown, Bermuda

              (C)     James T. Martin is a lecturer, author and consultant.

              (D)     During the past five  years,  James T. Martin has not been
                      convicted  in a  criminal  proceeding,  excluding  traffic
                      violations or similar misdemeanors.

              (E)     During the past five years, James T. Martin has not been a
                      party   to  a   civil   proceeding   of  a   judicial   or
                      administrative body of competent  jurisdiction and has not
                      been  subject  to  a  judgment,   decree  or  final  order
                      enjoining   future   violations   of,  or  prohibiting  or
                      mandating   activities   subject  to,   federal  or  state
                      securities  laws or finding any violation  with respect to
                      such laws.

              (F)     James T. Martin is a citizen of Bermuda  (subject of Great
                      Britain).


Item 3.       Source and Amount of Funds and Other Consideration

              The total  amount of the funds  used in making the  purchases  was
              $17,011,647. The sources of the funds used in making the purchases
              were personal funds.




                               Page 3 of 6 Pages
<PAGE>

Item 4.       Purpose of Transaction

              James  T.  Martin  has  purchased   shares  of  Common  Stock  for
              investment purposes.

              There are no plans or  proposals  which  James T.  Martin may have
              that relate to or would result in:

              (A)     The acquisition by any person of additional  securities of
                      the  Issuer,  or  the  disposition  of  securities  of the
                      Issuer, except as otherwise disclosed herein;

              (B)     An extraordinary corporate transaction,  such as a merger,
                      reorganization or liquidation, involving the Issuer or any
                      of its subsidiaries;

              (C)     A sale or transfer  of a material  amount of assets of the
                      Issuer or of any of its subsidiaries;

              (D)     Any change in the present board of directors or management
                      of the Issuer,  including any plans or proposals to change
                      the number or term of  directors  or to fill any  existing
                      vacancies on the board;

              (E)     Any  material  change  in the  present  capitalization  or
                      dividend policy of the Issuer;

              (F)     Any other  material  change in the  Issuer's  business  or
                      corporate structure;

              (G)     Changes in the  Issuer's  charter,  bylaws or  instruments
                      corresponding  thereto or other  actions  which may impede
                      the acquisition of control of the Issuer by any person;

              (H)     Causing a class of securities of the Issuer to be delisted
                      from a  national  securities  exchange  or to  cease to be
                      authorized  to  be  quoted  in an  inter-dealer  quotation
                      system of a registered national securities association;

              (I)     A  class  of  equity  securities  of the  Issuer  becoming
                      eligible  for  termination  of  registration  pursuant  to
                      Section  12(g)(4) of the Securities  Exchange Act of 1934,
                      as amended; or

              (J)     Any action similar to any of those enumerated above.



                               Page 4 of 6 Pages
<PAGE>

Item 5.       Interest in Securities of the Issuer

              (A)     The  aggregate  number  and  percentage  of  Common  Stock
                      beneficially  owned by James T. Martin are 625,090  Shares
                      and 5.0%, respectively.

              (B)     James T.  Martin  has the sole  power to vote or to direct
                      the vote of all the  shares  identified  pursuant  to Item
                      5(a).  Mr. Martin does not have any power to dispose or to
                      direct  the  disposition  of  all  the  shares  identified
                      pursuant to Item 5(a).

              (C)     Transactions in the securities identified pursuant to Item
                      5(a) during the past 60 days are as follows:

    Beneficial       Trans.        Amount of       Price Per         Where/How
      Owner           Date        Transaction        Share           Effected

   J.T. Martin      11/16/98        $360,626         $24.04         Open Market
   J.T. Martin      11/17/98        $232,877         $23.28         Open Market
   J.T. Martin      11/19/98        $240,356         $24.03         Open Market
   J.T. Martin      11/27/98        $480,960         $25.31         Open Market
   J.T. Martin      12/03/98        $244,312         $24.43         Open Market
   J.T. Martin      12/04/98      $1,251,751         $25.03         Open Market
   J.T. Martin      12/08/98        $248,851         $24.88         Open Market
   J.T. Martin      12/14/98        $239,351         $23.93         Open Market
   J.T. Martin      12/15/98        $240,601         $24.06         Open Market
   J.T. Martin      12/21/98        $233,101         $23.31         Open Market
   J.T. Martin      12/24/98        $235,231         $23.52         Open Market
   J.T. Martin      01/04/99        $219,291         $21.92         Open Market
   J.T. Martin      01/11/99        $252,671         $25.26         Open Market


              (D)     Not applicable.

              (E)     Not applicable.


Item 6.       Contracts,  Arrangements,  Understandings  or  Relationships  with
              Respect to Securities of the Issuer

              None


Item 7.       Material to be Filed as Exhibits

              None




                               Page 5 of 6 Pages
<PAGE>

                                   SIGNATURES

         After reasonable  inquiry and to the best of my knowledge and belief, I
certify  that the  information  set forth in this  statement  on Schedule 13D is
true, complete and correct.


                                             James T. Martin



Date:  January 11, 1999                      /s/ James T. Martin                
                                             -----------------------------------
                                             James T. Martin




Attention:    Intentional  misstatements or omissions of fact constitute Federal
              criminal violations (see 18 U.S.C. 1001).





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