DIAMETRICS MEDICAL INC
DEF 14A, 1996-05-20
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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<PAGE>
 
                           SCHEDULE 14A INFORMATION

          Proxy Statement Pursuant to Section 14(a) of the Securities
                    Exchange Act of 1934 (Amendment No.  )
        
Filed by the Registrant [X]

Filed by a Party other than the Registrant [_] 

Check the appropriate box:
    
[_]  Preliminary Proxy Statement         [_]  CONFIDENTIAL, FOR USE OF THE
                                              COMMISSION ONLY (AS PERMITTED BY
                                              RULE 14A-6(E)(2))

[X]  Definitive Proxy Statement 
     
[_]  Definitive Additional Materials 

[_]  Soliciting Material Pursuant to Section 240.14a-11(c) or Section 240.14a-12

                           DIAMETRICS MEDICAL, INC.
- --------------------------------------------------------------------------------
               (Name of Registrant as Specified In Its Charter)


- --------------------------------------------------------------------------------
   (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

   
Payment of Filing Fee (Check the appropriate box):
    
[_]  $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), 14a-6(i)(2)
     or Item 22(a)(2) of Schedule 14A.
     
[_]  $500 per each party to the controversy pursuant to Exchange Act Rule
     14a-6(i)(3).

[_]  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

   
     (1) Title of each class of securities to which transaction applies:

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     (2) Aggregate number of securities to which transaction applies:

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     (3) Per unit price or other underlying value of transaction computed
         pursuant to Exchange Act Rule 0-11 (Set forth the amount on which
         the filing fee is calculated and state how it was determined):

     -------------------------------------------------------------------------
      

     (4) Proposed maximum aggregate value of transaction:

     -------------------------------------------------------------------------


     (5) Total fee paid:
  
     -------------------------------------------------------------------------
    
[X]  Fee paid previously with preliminary materials.
          
[_]  Check box if any part of the fee is offset as provided by Exchange
     Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee
     was paid previously. Identify the previous filing by registration statement
     number, or the Form or Schedule and the date of its filing.
     
     (1) Amount Previously Paid:
 
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     (2) Form, Schedule or Registration Statement No.:

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     (3) Filing Party:
      
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     (4) Date Filed:

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Notes:
<PAGE>
 
                           DIAMETRICS MEDICAL, INC.
                               2658 PATTON ROAD
                          ROSEVILLE, MINNESOTA 55113

                   NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                                 JUNE 27, 1996

TO THE SHAREHOLDERS OF DIAMETRICS MEDICAL, INC.:

     Notice is hereby given that the Annual Meeting of Shareholders of
Diametrics Medical, Inc. (the "Company") will be held at 3:30 p.m. on Thursday,
June 27, 1996, at the Minneapolis Hilton, 1001 Marquette Avenue, Minneapolis,
Minnesota, for the following purposes:

     1.   To elect seven members to the Board of Directors to serve for a term
          beginning June 30, 1996 and until their terms expire and until their
          successors are elected and qualified.

     2.   To approve an amendment to the Company's Bylaws providing for a
          classified Board of Directors, with the effect that approximately one-
          third of the Company's directors will be elected each year, and to
          approve certain other related amendments to the Bylaws and Restated
          Articles of Incorporation of the Company.

     3.   To consider and vote upon an amendment to the Company's 1990 Stock
          Option Plan to increase the number of shares of Common Stock available
          for issuance thereunder from 1,740,000 shares to 3,000,000 shares.

     4.   To consider and vote upon an amendment to the Company's 1993
          Directors' Stock Option Plan to increase the initial grant to
          directors thereunder from 10,000 shares to 14,500 shares and to
          increase subsequent annual grants to directors thereunder from 1,500
          to 4,000 shares.

     5.   To consider and vote upon an amendment to the Company's 1995 Employee
          Stock Purchase Plan to increase the number of shares of Common Stock
          available for issuance thereunder from 150,000 shares to 300,000
          shares.

     6.   To consider and act upon a proposal to approve the Company's 1995
          Directors' Equalizing Options.

     7.   To consider and act upon such other matters as may properly come
          before the meeting or any adjournment thereof.

     The Board of Directors has fixed the close of business on April 29, 1996
as the record date for the determination of shareholders entitled to notice of
and to vote at the meeting or any adjournment thereof.  A copy of the Company's
annual report is included with this mailing, which is being first made available
on approximately the date shown below.

     We encourage you to take part in the affairs of your Company either in
person or by executing and returning the enclosed proxy.

                                       By Order of the Board of Directors,
                                        
                                       /s/ Kenneth L. Cutler     

                                       Kenneth L. Cutler
                                       Secretary
    
Dated:  May 20, 1996    
            
WHETHER OR NOT YOU PLAN TO ATTEND THIS MEETING, PLEASE MARK, DATE AND SIGN THE
ENCLOSED PROXY AND RETURN IT PROMPTLY IN THE ENCLOSED ENVELOPE.  IF YOU LATER
DESIRE TO REVOKE YOUR PROXY, YOU MAY DO SO AT ANY TIME BEFORE IT IS EXERCISED.
<PAGE>
 
                           DIAMETRICS MEDICAL, INC.

                               2658 PATTON ROAD
                          ROSEVILLE, MINNESOTA 55113



                               -----------------



                                PROXY STATEMENT
                                      FOR
                        ANNUAL MEETING OF SHAREHOLDERS
                                 JUNE 27, 1996

    
     This Proxy Statement is furnished in connection with the solicitation of
proxies by the Board of Directors of Diametrics Medical, Inc. (the "Company")
for use at the Annual Meeting of Shareholders to be held on Thursday, June 27,
1996, at the Minneapolis Hilton, 1001 Marquette Avenue, Minneapolis, Minnesota
at 3:30 p.m., Minneapolis time, and at any adjournment thereof, for the purposes
set forth in the Notice of Annual Meeting of Shareholders. This Proxy Statement
and the form of proxy enclosed are being mailed to shareholders commencing on or
about May 20, 1996.     

     Shares of the Common Stock, $.01 par value (the "Common Stock"),
represented by proxies in the form solicited will be voted in the manner
directed by a shareholder. If no direction is made, the proxy will be voted for
the election of the nominees for director named in this Proxy Statement. Shares
voted as abstentions on any matter will be counted as shares that are present
and entitled to vote for purposes of determining the presence of a quorum at the
meeting and as unvoted, although present and entitled to vote, for purposes of
determining the approval of each matter as to which the shareholder has
abstained. If a broker submits a proxy which indicates that the broker does not
have discretionary authority as to certain shares to vote on one or more
matters, those shares will be counted as shares that are present and entitled to
vote for purposes of determining the presence of a quorum at the meeting, but
will not be considered as present and entitled to vote with respect to such
matters. Proxies may be revoked at any time before being exercised, by delivery
to the Secretary of the Company of a written notice of termination of the
proxies' authority or a duly executed proxy bearing a later date.

     All holders of the Common Stock whose names appear of record on the
Company's books at the close of business on April 29, 1996 will be entitled to
vote at the Annual Meeting or any adjournment thereof.  At the close of business
on April 29, 1996, a total of 15,123,395 shares of Common Stock were
outstanding, each share being entitled to one vote.  Officers, directors and
regular employees of the Company, who will receive no extra compensation for
their services, may solicit proxies by telephone or in person.  Expenses in
connection with the solicitation of proxies will be paid by the Company.

     So far as the management of the Company is aware, no matters other than
those described in this Proxy Statement will be acted upon at the meeting. In
the event that any other matters properly come before the meeting calling for a
vote of shareholders, the persons named as proxies in the enclosed form of proxy
will vote in accordance with their best judgment on such other matters.

     A copy of the Company's Annual Report for the year ended December 31, 1995
is being furnished to each shareholder with this Proxy Statement.
<PAGE>
 
                        ITEM 1:  ELECTION OF DIRECTORS

     The Company's Bylaws provide that the number of directors will be the
number established by resolution of the Board of Directors.  The Board of
Directors has established the number of directors to be elected for the coming
year at seven.  If the proposed amendments to the Company's Bylaws and Restated
Articles of Incorporation concerning classification of the Board of Directors
are adopted, James E. Ashton, Ph.D. and Fred E. Silverstein, M.D. are to be
elected for terms beginning effective June 30, 1996 and expiring at the Annual
Meeting in 1997; Gerald L. Cohn and Mark B. Knudson, Ph.D. are to be elected for
terms beginning effective June 30, 1996 and expiring at the Annual Meeting in
1998; and David T. Giddings, Andre de Bruin and Richard A. Norling are to be
elected for terms beginning effective June 30, 1996 and expiring at the Annual
Meeting in 1999 (or, in all cases, until their respective successors are elected
and qualified).  If the amendments are not adopted, all seven nominees will be
elected for terms expiring at the Annual Meeting in 1997 (or until their
respective successors are elected and qualified).  The persons named as proxies
in the enclosed form of proxy will vote for the election of the seven persons
named above as directors, unless otherwise directed in the proxy.  Only Mark B.
Knudson, Ph.D., James E. Ashton, Ph.D. and Fred E. Silverstein, M.D. are
presently directors of the Company.  The nominees have indicated a willingness
to serve, but in case a nominee is not a candidate at the meeting, for reasons
not now known to the Company, the proxies named in the enclosed form of proxy
may vote for a substitute nominee in their discretion.

     Certain biographical information furnished by the Company's current
directors and nominees for director is presented below.

<TABLE>
<CAPTION>
     Name                          Age             Position
     ----                          ---             --------
<S>                                <C>      <C>
Michael F. Connoy                  47       President and Director
Mark B. Knudson, Ph.D.(3)          47       Chairman of the Board 
                                             and Director
James E. Ashton, Ph.D.(2)          53       Director
Ronald E. Eibensteiner(1)(2)(3)    45       Director
William E. Engbers                 53       Director
Ronald A. Matricaria(3)            53       Director
Timothy I. Maudlin(1)(2)           45       Director
Walter L. Sembrowich, Ph.D.        53       Director
Fred E. Silverstein, M.D.          53       Director
Timothy A. Stepanek(1)(3)          47       Director
Richard A. Norling                 50       Director Nominee
David T. Giddings                  52       Chief Executive Officer
                                             and Director Nominee
Gerald L. Cohn                     67       Director Nominee
Andre de Bruin                     49       Director Nominee
- ----------------
</TABLE>

(1)  Member of the Compensation Committee of the Board of Directors.
(2)  Member of the Audit Committee of the Board of Directors.
(3)  Member of Nominating Committee of the Board of Directors.

     Mr. Connoy has been President and a director of the Company since February
1993.  He was Chief Executive Officer from February 1993 until April 1996.  From
April 1988 until January 1993, Mr. Connoy was President and Chief Operating
Officer of Empi, Inc., a manufacturer and marketer of medical devices for the
physical therapy, orthopedic and rehabilitation markets.

                                      -2-
<PAGE>
 
     Dr. Knudson has been the Chairman of the Board of Directors since March
1995 and a director of the Company since March 1990. Since 1989, Dr. Knudson has
been a limited partner of Medical Innovation Partners and, since 1993, a
Managing Venture Partner of Medical Innovation Partners II, each a private
investment partnership active in the formation, management, financing and
development of start-up medical technology and service companies and the general
partners of Medical Innovation Fund, a Limited Partnership ("Medical Innovation
Fund") and Medical Innovation Fund II, a Limited Partnership ("Medical
Innovation Fund II"), respectively. Dr. Knudson is also a director of InControl,
Inc. and Heartstream, Inc.

     Dr. Ashton has been a director of the Company since September 1995. Since
October 1995 Dr. Ashton has been the Chief Executive Officer of Fiberite, Inc.,
a manufacturer of a broad range of composite materials used in aerospace,
sporting and industrial applications. Dr. Ashton has also been a limited partner
of Carlisle Enterprises, L.P., a mergers and acquisitions firm, since November
1993. From April 1989 to June 1994, Dr. Ashton served as the vice president and
general manager of the Armament Systems Division of United Defense, L.P./FMC.

     Mr. Eibensteiner has been a director of the Company since March 1990. Since
January 1993, he has served as President of Wyncrest Capital, a seed investor in
early stage technology companies. From 1990 to January 1993, Mr. Eibensteiner
was Chairman of the Board of the Company. From January 1988 to December 1992, he
served as President and Chief Executive Officer of Mirror Technologies,
Incorporated, currently a provider of engineering, brokerage, part and remote
support services to users of IBM mainframe computers. Mr. Eibensteiner also
serves as a director of IVI Publishing, Inc., an interactive multimedia
publisher of health and medical titles.
  
     Mr. Engbers has been a director of the Company since February 1995.  Since
June 1989, he has been the Venture Group Manager of Allstate Insurance Company.
Mr. Engbers is also a director of a La Jolla Pharmaceutical Company, Applied
Biometrics Inc. and DM Management Company.

     Mr. Matricaria has been a director of the Company since April 1994. Mr.
Matricaria has been President and Chief Executive Officer of St. Jude Medical,
Inc., a medical device company, since April 1993, and was elected Chairman of
the Board of that company in January 1995.  From 1970 to April 1993, Mr.
Matricaria was employed by Eli Lilly and Company, Inc., a developer and marketer
of pharmaceuticals, medical instruments and diagnostic products, where he most
recently served as President of the Medical Devices and Diagnostics Division,
Executive Vice President of the Pharmaceutical Division and President of its
North American Operations.  Mr. Matricaria is also a director of St. Jude
Medical Inc., Centocor, Inc., Reality Interactive, Inc. and InControl, Inc.

     Mr. Maudlin has been a director of the Company since March 1990. Mr.
Maudlin has been Managing General Partner of Medical Innovation Partners since
1988 and Managing General Partner of Medical Innovation Partners II since 1993.
Mr. Maudlin is also a director of Curative Technologies, Inc., and IVI
Publishing, Inc.

     Dr. Sembrowich has been a director of the Company since March 1990.  From
March 1995 through December 1995, Dr. Sembrowich served as Executive Vice
President of New Business Development of the Company.  From January 1993 to
March 1995 he served as a Co-Chairman of the Board. From March 1990 through
January 1993, he was Chief Executive Officer of the Company.  Dr. Sembrowich is
also a director of St. Jude Medical, Inc., a developer and marketer of heart
valves and other cardiovascular devices.

     Dr. Silverstein has been a director of the Company since February 1995. Dr.
Silverstein was on the faculty of the University of Washington Medical School
for over 20 years, most recently as a 

                                      -3-
<PAGE>
 
tenured professor of medicine. He is currently a Clinical Professor of Medicine.
Since 1994, he has been a partner of Frazier & Company L.P., an investment
partnership. He holds a B.S. from Alfred University and an M.D. from Columbia
University College of Physicians and Surgeons. He is Board Certified in internal
medicine and gastroenterology. Dr. Silverstein is also a director of Vision
Sciences Inc. and several privately-held companies. He holds more than 20 United
States patents on a variety of medical devices.

     Mr. Stepanek has been a director of the Company since June 1991. Since
1989, Mr. Stepanek has been a Managing Partner of Parsnip River Company, a
private investment limited partnership. Mr. Stepanek is also a director of
United Market Services Company.

     Mr. Norling has been President and Chief Executive Officer of Fairview
Hospital and HealthCare Services since July 1989.  From June 1988 to June 1989,
Mr. Norling was Executive Vice President and Chief Operating Officer of
UniHealth America ("UniHealth"), a nonprofit system of hospitals and health care
organizations headquartered in Burbank, California.  Prior to joining UniHealth,
Mr. Norling was employed in management positions with a variety of hospitals,
HMO's and healthcare related organizations that were predecessors to UniHealth,
including Executive Vice President and Chief Operating Officer of LHS
Corporation and President and Executive Director of the California Medical
Center, both located in Los Angeles.  Mr. Norling is currently a member of the
American Hospital Association and Executive Committee member of American
Healthcare Systems.  Mr. Norling also serves as a director of Express Scripts,
Inc., a managed care pharmaceutical company.

     Mr. Giddings has been Chief Executive Officer of the Company since April
1996.  Prior to that time, he had been employed by Boehringer Mannheim
Corporation ("BMC"), an in-vitro diagnostic company, since 1992 and has been
President and Chief Operating Officer of BMC since June 1994.  Prior to joining
BMC, Mr. Giddings was employed by Eastman Kodak Company for 26-1/2 years, where
he most recently served as Vice President and General Manager, Printing and
Publishing Division.

     Mr. Cohn has been a private investor and consultant since 1991. From 1988
to 1991, Mr. Cohn participated with the Pritzker Family of Chicago with the
funding and restructuring for Monoclonal Antibodies, Inc. ("MABS"). Prior to
assisting MABS, Mr. Cohn assisted various companies restructure and attain
profitability, including DVI Inc., a health service finance company, and Pepco,
Inc., a large ferrous and non-ferrous metal recycle, and ferrous stevedoring and
shipping company. Mr. Cohn also serves as a director of DVI Inc., SMT Health
Services, Inc., a mobile diagnostic services provider, and International Metals
Acquisition Corp., a steel manufacturing company.

     Mr. de Bruin was appointed President and Chief Executive Officer of
Somatogen Corporation on July 13, 1994. On January 22, 1996, he was elected
Chairman of the Board of Somatogen. Immediately prior to joining Somatogen, he
was Chairman, President and Chief Executive Officer of Boehringer Mannheim
Corporation, Indianapolis, Indiana, the U.S. subsidiary of Corange Ltd., a
private, global health care corporation with sales exceeding $3 billion. He held
that position since 1989. Mr. de Bruin serves on the Board of Directors of both
DIANON Systems, Inc., a public company specializing in oncology and genetic
laboratory services, and BioStar, Inc., a private bio-diagnostics company based
in Boulder, Colorado.

BOARD COMMITTEES; ATTENDANCE

     The Board of Directors has a Compensation Committee which consisted of
Messrs. Eibensteiner, Maudlin and Stepanek (none of whom are standing for
reelection).  The Compensation Committee held one meeting during the year ended
December 31, 1995.  The Compensation Committee of the Board of Directors makes
recommendations concerning executive salaries and incentive compensation for

                                      -4-
<PAGE>
 
employees of the Company, subject to ratification by the full Board, and
administers the 1990 Stock Option Plan.

     The Board of Directors of the Company has an Audit Committee which
consisted of Dr. Ashton and Messrs. Eibensteiner and Maudlin (of whom Messrs.
Eibensteiner and Maudlin are not standing for reelection). The Audit Committee
held two meetings during the year ended December 31, 1995. The Audit Committee
reviews the results and scope of the audit and other services provided by the
Company's independent auditors, as well as the Company's accounting principles
and its system of internal controls, and reports the results of their review to
the full Board and to management.

     The Board of Directors of the Company has a Nominating Committee which
consists of Dr. Knudson and Messrs. Eibensteiner, Matricaria and Stepanek (of
whom Messrs. Eibensteiner, Matricaria and Stepanek are not standing for
reelection).  The Nominating Committee held two meetings during the year ended
December 31, 1995.  The Nominating Committee of the Board of Directors makes
recommendations concerning members of the Board of Directors and other matters
relevant to the Company's organizational structure.

     During the year ended December 31, 1995, the Board of Directors held six
meetings.  All incumbent directors attended at least 75% of the aggregate of
those meetings of the Board and committees of which they were members that were
held while they were serving on the Board or on such committee.  The Company's
Board and committees also act from time to time by written consent in lieu of
meetings.

DIRECTOR COMPENSATION

     Members of the Board of Directors who are not employees of the Company will
receive $1,000 per Board meeting attended during the 12 month period ending July
1, 1996 and each 12 month period thereafter, provided that if there are less
than 12 Board meetings in any such 12 month period, each non-employee Board
member will receive $2,000 for each Board meeting attended in person ($500 if
attended by telephone) and an additional fee equal to (a) $1,000 times (b) 12
minus the actual number of Board meetings held in such 12 month period.  In
addition, effective July 1, 1995, each non-employee member of the Board of
Directors of the Company serving on the Compensation Committee, the Audit
Committee and/or the Nominating Committee will receive $250 per committee
meeting attended.  All directors are reimbursed for expenses actually incurred
in attending meetings of the Board of Directors and its committees.

     In addition, non-employee directors are eligible to participate in the
Company's 1993 Directors' Stock Option Plan (the "Directors' Plan").  The
Directors' Plan provides for an automatic grant of nonqualified stock options to
purchase 10,000 shares of Common Stock to non-employee directors of the Company
on the later of June 15, 1993 or the date such individuals become directors of
the Company (the "Initial Grant"), and an option to purchase 1,500 shares of
Common Stock on each subsequent annual shareholder meeting date (the "Subsequent
Grant"), subject to certain limitations.  In August 1995 the Board of Directors
approved an amendment to the Directors' Plan to increase the Initial Grant of
options to directors joining the Company after such date from 10,000 shares to
14,500 shares, subject to shareholder approval.   In April 1996, the Board of
Directors approved an amendment to the Directors' Plan to increase the
Subsequent Grant of options to directors at each annual shareholder meeting from
1,500 to 4,000 shares, subject to shareholder approval.  See "Proposal to Amend
Directors' Plan."

     Options granted in connection with the Initial Grant vest and become
exercisable as to 50% of such shares on the twelve month anniversary of the date
of such Initial Grant and 25% at each such successive anniversary date
thereafter if the holder remains a director on such dates.  Options granted 

                                      -5-
<PAGE>
 
on the date of each annual meeting of shareholders become exercisable six months
subsequent to the date of grant. The Company has reserved 217,500 shares of
Common Stock for issuance under the Directors' Plan. The option price for
directors is equal to the fair market value (based on the Nasdaq Stock Market
closing price) of the Common Stock on the date of grant. Options to purchase an
aggregate of 113,000 shares have been automatically granted under the Directors'
Plan to Messrs. Eibensteiner, Engbers, Matricaria, Maudlin and Stepanek and Drs.
Ashton, Knudson and Silverstein. Options to purchase an aggregate of 59,500
additional shares of Common Stock will be issued under the Directors' Plan as of
the date of the Annual Meeting, assuming the election by the shareholders of
Messrs. Norling, Giddings, Cohn and de Bruin and Drs. Ashton, Knudson and
Silverstein. Mr. Maudlin and Mr. Stepanek have assigned all of their options and
Dr. Knudson has assigned 2,900 of his options to the venture capital funds for
which they serve as designee on the Company's Board of Directors pursuant to the
partnership agreements or policies of such funds.

     In order to equalize the number of options granted to each of the Company's
outside directors, the Compensation Committee and the Board of Directors
approved the additional one-time grant of options (the "Directors' Equalizing
Options") to purchase 4,500 shares of Common Stock at an exercise price of $9.75
per share (the fair market value on the date of grant) to each of Messrs.
Engbers and Matricaria and Dr. Silverstein.  Such options terminate on June 29,
2005, vest with respect to 50% of such shares on June 29, 1996 and vest with
respect to an additional 25% of such shares on June 29, 1997 and June 29, 1998,
respectively.  The Directors' Equalizing Options are subject to shareholder
approval.  See "Proposal to Approve Directors' Equalizing Options."

     In addition to the options granted as set forth above under the Directors'
Plan, Dr. Knudson received options to purchase an aggregate of 14,500 shares at
an exercise price of $9.75 per share (the fair market value of the Common Stock
on the date of grant) under the Company's 1990 Stock Option Plan as compensation
for his services to the Company as Chairman of the Board of Directors.  Such
options terminate on June 29, 2005, vest with respect to 50% of such shares on
June 29, 1996 and vest with respect to an additional 25% of such shares on June
29, 1997 and June 29, 1998, respectively.

   Effective December 21, 1995, the Company and Walter L. Sembrowich, Ph.D.
entered into a Severance/Consulting Agreement (the "Consulting Agreement") with
a term expiring on December 31, 1997. Under the Consulting Agreement, Dr.
Sembrowich retired from the Company effective December 31, 1995. In
consideration for his promises and obligations under the Consulting Agreement,
including his agreement to certain restrictions on his ability to compete with
the Company until December 31, 1998 and his release of the Company from all
claims, Dr. Sembrowich received a severance of $150,000 upon his retirement on
December 31, 1995. In addition, all options previously granted but not vested as
of December 21, 1995, vested as of such date and Dr. Sembrowich was given four
years from December 21, 1995 to exercise any unexercised options on the
Company's Common Stock. Dr. Sembrowich is also entitled to participate in the
Company's group health insurance program.

     Further, pursuant to the Consulting Agreement, from January 1, 1996 through
and including December 31, 1997 (the "Consulting Term"), Dr. Sembrowich agreed
to serve as a consultant to the Company without charge to the Company.  Dr.
Sembrowich has agreed to keep all confidential information acquired by him
during his employment with the Company and during the Consulting Term in
confidence.

     The affirmative vote of a majority of the shares of Common Stock
represented at the meeting is required for the election of the nominees for
director. THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE ELECTION OF THE
NOMINEES.

                                      -6-
<PAGE>
 
                            EXECUTIVE COMPENSATION

REPORT OF COMPENSATION COMMITTEE ON EXECUTIVE COMPENSATION

     Under rules established by the Securities and Exchange Commission, the
Company is required to provide certain data and information in regard to the
compensation and benefits provided to the Company's Chief Executive Officer and
its other executive officers.  The disclosure requirements for these individuals
(the "executive officers") include the use of tables and a report explaining the
rationale and considerations that led to fundamental executive compensation
decisions affecting those individuals.  In fulfillment of the report
requirement, the Compensation Committee of the Board of Directors (the
"Committee"), at the direction of the Board of Directors, has prepared the
following report for inclusion in this Proxy Statement.

     OVERVIEW

     The Committee is responsible for establishing and making certain
recommendations to the Board of Directors concerning executive compensation,
including annual base salaries, stock options and other benefits.  The Committee
is composed entirely of independent outside directors of the Company.  The
Committee annually reviews and evaluates the Company's corporate performance,
compensation levels and equity ownership of its executive officers.  The goal of
the Committee is to establish compensation policies and programs that will
attract and retain highly qualified executives and provide an incentive to such
executives to focus on the Company's long-term strategic goals by aligning their
financial interests closely with long-term shareholder interests.

     The Committee intends to make the executive compensation program
competitive with the marketplace, with emphasis on compensation in the form of
equity ownership, the value of which is contingent on the Company's long-term
market performance. For this purpose, the Committee compares the Company with a
self-selected group of development stage companies with similar business
characteristics and strategies.

     In addition, since the Company has only recently begun commercial
production and full-scale marketing of its product, it is difficult to select
objective criteria by which to measure individual and Company performance.  As a
result, the Committee's efforts to tie compensation to performance involve a
subjective element and take into account the achievement of such nonfinancial
goals such as development of the Company's sales and marketing force and growing
market acceptance of the Company's IRMA(TM) (Immediate Response Mobile Analysis)
System. In evaluating compensation relative to Company performance, the
Committee also considers the Company's stock performance and progress toward
profitability.  In the future, the Committee intends to implement a bonus 
program that will be tied to specific financial goals, including operating
revenues and earnings.

     EXECUTIVE COMPENSATION PROGRAM

     The components of the Company's executive compensation program which are
subject to the discretion of the Committee on an individual basis consist
primarily of base salaries, bonuses and stock options.  The ultimate composition
of executive compensation reflects the Company's goals of attracting and
retaining highly qualified personnel and supporting a performance-oriented
environment that rewards both corporate and personal performance over the long
term.  In general, stock option grants are used to enhance the competitiveness
of compensation packages, to reward exceptional performance and provide
incentive for reaching further performance goals.

                                      -7-
<PAGE>
 
     BASE SALARY AND BONUS.  Annual base salaries and bonuses are established as
a result of the Committee's analysis of each executive officer's individual
performance during the prior year, the overall performance of the Company during
the prior year and historical compensation levels within the executive officer
group.

     STOCK OPTIONS.  The Company's 1990 Stock Option Plan (the "Stock Option
Plan") is designed to align a portion of executive and other senior employee
compensation with the long-term interests of shareholders.  The Stock Option
Plan permits the granting of several different types of stock-based awards to a
broad range of employees.  To date, the Committee has awarded both stock options
and performance awards under the Stock Option Plan.  For a description of the
performance awards, see "--Stock Bonus Program" below.  The stock options give
the holder the right to purchase shares of the Common Stock over a ten-year
period at the fair market value per share as of the date the option is granted.

     In determining whether to grant options to an executive officer, the
Committee typically considers the individual's performance as such performance
relates to the achievement of Company objectives and any planned change in
functional responsibility.  Although the stock option position of executive
officers generally is reviewed on an annual basis, the Company's policy is to
not grant stock options annually, but to review each individual's stock option
position, at which point the Committee may or may not grant additional options
in its discretion.  The determination of whether any additional options will be
granted to an executive officer is based on a number of factors, including
Company performance, individual performance and levels of options granted by the
comparable companies referred to above.

     STOCK BONUS PROGRAM.  In 1995, the Committee established a stock award
program for all of the Company's employees, pursuant to which employees may be
granted unrestricted stock awards of 100 shares each, based upon the achievement
of certain Company performance milestones.  Two such performance milestones were
established and achieved in 1995, resulting in two grants of 100 shares each to
all employees on the date of grant.  The first milestone established and
achieved was the Company's release of its Electrolyte Cartridge on June 29, 1995
and the second milestone established and achieved was the achievement of a
twelve week shelf life on the Company's Blood Gas Cartridge by October 1995.

     COMPENSATION OF CHIEF EXECUTIVE OFFICER

     Compensation for the Chief Executive Officer consists of the following
components: base salary and stock options.  Mr. Connoy joined the Company in
February 1993 as Chief Executive Officer.  His 1993 annual base salary was set
at $175,000, and he was granted stock options to purchase 217,500 shares of
Common Stock.  Mr. Connoy's original compensation package was established by the
Committee based on the general experience of the Committee members in dealing
with compensation matters at other emerging growth companies, and was designed
to attract an individual with Mr. Connoy's abilities and experience to the
Company.  In 1994, Mr. Connoy's base salary increased 14% over the prior year to
$200,000, as a result of the Committee's efforts to make his salary competitive
with comparable companies, based on the Committee's informal review.  There was
no adjustment to Mr. Connoy's base salary in 1995.

     In addition to base salary, in 1995 Mr. Connoy received two grants of 100
unrestricted shares of Common Stock under the Company's Stock Bonus Program
described above.  Mr. Connoy received no additional stock options in 1995.  The
Committee believes that stock options granted to Mr. Connoy to date provide a
significant and appropriate tie between overall compensation and the performance
of the Company over the long term.

                                      -8-
<PAGE>
 
     SECTION 162(M)

     Section 162(m) of the Internal Revenue Code of 1986, as amended (the
"Code"), did not affect the deductibility of compensation paid to the Company's
executive officers in 1995 and will not effect the deductibility of such
compensation expected to be paid in 1996. The Committee will continue to monitor
this matter and may propose additional changes to the executive compensation
program if warranted.

RONALD E. EIBENSTEINER,
TIMOTHY I. MAUDLIN and
TIMOTHY A. STEPANEK,
The Members of the Compensation Committee

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
  
     Ronald E. Eibensteiner, Mark B. Knudson, Ph.D., Timothy I. Maudlin and
Timothy A. Stepanek served as members of the Company's Compensation Committee
during 1995.  Dr. Knudson resigned from, and Mr. Stepanek was elected to, such
committee effective March 17, 1995.

     Mr. Eibensteiner served as Chairman of the Board of Directors of the 
Company from 1990 to January 1993, although he received no compensation from 
the Company for serving in such capacity.  Dr. Knudson has served as Chairman 
of the Board of Directors of the Company since March 1995 and, although he is 
not an employee of the Company, has received options to purchase 14,500 shares
of Common Stock as described above under "Election of Directors--Director 
Compensation" as compensation for his services as Chairman of the Board.

     Dr. Knudson is a limited partner and Mr. Maudlin is Managing General
Partner of Medical Innovation Partners, the general partner of Medical
Innovation Fund. The Company has a sublease agreement with FIM, Inc. ("FIM"), a
wholly-owned subsidiary of Medical Innovation Fund. Pursuant to this agreement,
FIM leases approximately $1,300,000 in laboratory and computer equipment from an
unrelated third party, which equipment is, in turn, subleased by the Company
from FIM on the same terms as the original lease. The Company's lease
obligations are guaranteed by Medical Innovation Fund. The Company pays FIM an
amount equal to FIM's lease payments. In connection with this sublease, the
Company has issued warrants to purchase an aggregate of 290,994 shares of Common
Stock at a weighted average exercise price of $2.25 per share, to Medical
Innovation Fund. Medical Innovation Fund has guaranteed total lease obligations
of FIM of up to $1,300,000.

                                      -9-
<PAGE>
 
SUMMARY COMPENSATION TABLE

     The following table sets forth the cash and noncash compensation for each
of the last three fiscal years awarded to or earned by the Chief Executive
Officer and the other four most highly compensated executive officers of the
Company:

<TABLE>
<CAPTION>

                                                                             LONG-TERM
                                                                           COMPENSATION
                                                                              AWARDS
                                               ANNUAL COMPENSATION         -------------
                                               -------------------         STOCK OPTIONS          ALL OTHER
                                   YEAR        SALARY        BONUS           (SHARES)            COMPENSATION
                                   ----        ------        -----         -------------         ------------
<S>                                <C>        <C>            <C>           <C>                   <C>

Michael F. Connoy                  1995       $198,735           --                   --                --
 President and Chief               1994        200,000           --               40,000                --
  Executive Officer                1993        150,000           --              217,000                --

David W. Deetz                     1995        150,000           --                   --                --
 Executive Vice President of       1994        150,000           --               40,000                --
  Operations and Chief             1993        130,000           --                   --                --
  Technical Officer (1)

James R. Miller                    1995        143,269       25,000              100,000         $  88,839(3)
 Vice President of Sales           1994             --           --                   --                --
  and Marketing (2)                1993             --           --                   --                --

Barbara E. Roth                    1995        126,085           --                5,000                --
 Vice President of                 1994         83,499           --                5,000                --
  Manufacturing (4)                1993         74,511           --               21,750                --

Walter L. Sembrowich, Ph.D.        1995        150,000           --                   --           150,000(6)
 Executive Vice President of       1994        150,000           --               40,000                --
 New Business                      1993        130,000           --                   --                --
 Development (5)
</TABLE>
- ----------------

(1)  Mr. Deetz's employment with the Company terminated on February 2, 1996.

(2)  Mr. Miller was employed by the Company on March 20, 1995.

(3)  Includes a relocation expense reimbursement.

(4)  Ms. Roth's employment with the Company terminated on March 1, 1996.

(5)  Dr. Sembrowich's employment with the Company terminated on December 31,
     1995 and in connection therewith he received a severance payment of
     $150,000.  See "Election of Directors--Director Compensation."

EMPLOYMENT CONTRACTS AND CHANGE IN CONTROL AGREEMENTS

     Except as provided below, none of the Company's executive officers has a
written employment agreement.  The Company has a letter agreement with Michael
F. Connoy to continue his monthly salary for a period of up to a maximum of six
months or when he accepts a new position, whichever occurs first, in the event
of a termination of his employment for other than cause.  The Company has agreed
that it will pay Mr. Deetz his then current base salary for a period of twelve
months from the 

                                      -10-
<PAGE>
 
date of any termination by Mr. Deetz of his employment with the Company for
"good reason" (as defined in such agreement). Pursuant to this agreement, the
Company will pay Mr. Deetz $150,000 for the twelve month period commencing on
February 2, 1996 (Mr. Deetz's termination date).

     Barbara E. Roth has resigned as an employee of the Company effective as of
March 1, 1996.  Pursuant to an agreement between the Company and Ms. Roth, she
will receive an aggregate of $216,000 in consideration for her promises and
obligations under the agreement, including her agreement to release the Company
from all claims and certain nondisclosure, noncompetition and nonsolicitation
covenants.  In addition, Ms. Roth was given 90 days to exercise any of her
vested options to purchase shares of the Company's Common Stock.

     The Company's consulting agreement with Walter L. Sembrowich is described
above under "Election of Directors--Director Compensation."

     As described below in footnote 1 to the table entitled "Option Grants
During the Year Ended December 31, 1995," the exercisability of options granted
to named executive officers is accelerated in the event of a "change in control"
involving the Company.

STOCK OPTIONS

     The following table summarizes option grants during the year ended
December 31, 1995 to the executive officers named in the "Summary Compensation
Table" above:

               OPTION GRANTS DURING YEAR ENDED DECEMBER 31, 1995
<TABLE>
<CAPTION>

                                           % of                                                     Potential
                                           Total                                                 Realizable Value
                                          Options                                               At Assumed Annual
                                          Granted          Exercise                            Rates of Stock Price
                                            to              or Base                                Appreciation
                                         Employees         Exercise                            for Option Term (3)
                          Options        in Fiscal           Price        Expiration       ----------------------------
      Name              Granted (1)      Year 1995       Per Share (2)       Date            5%                  10%
- ------------------     ------------     -----------     ---------------  ------------      -------             --------
<S>                    <C>              <C>             <C>              <C>               <C>                 <C> 
James R. Miller..           100,000            32%       $      6.00      March 2005       377,337             956,245

Barbara E. Roth..             5,000             2%       $      7.38      June 2005         23,206              58,809
</TABLE>
- ------------------

(1)  Each option represents the right to purchase one share of Common Stock.
     The stock option grants shown in this column were all made in March 1995
     and June 1995 pursuant to the Stock Option Plan, became exercisable with
     respect to 25% of the shares on the date of grant, and 25% on each
     successive anniversary date for three years.  To the extent not already
     exercisable, the options become exercisable in the event of a "change in
     control" (as defined in the stock option agreement) involving the Company.

(2)  The exercise price is equal to the fair market value of the Common Stock on
     the date of grant in the case of each of such grants.  The exercise price
     may be paid in cash, in shares of Common Stock with a market value as of
     the date of exercise equal to the option price or a combination of cash and
     shares of Common Stock.

(3)  The compounding assumes a ten-year exercise period for all option grants.
     These amounts represent certain assumed rates of appreciation only.  Actual
     gains, if any, on stock option 

                                      -11-
<PAGE>
 
     exercises are dependent on the future performance of the Common Stock, and
     overall stock market conditions. The amounts reflected in this table may
     not necessarily be achieved.

     The following table summarizes the value realized upon exercise of options
in the year ended December 31, 1995 and the value of options held at
December 31, 1995 by the executive officers named in the "Summary Compensation
Table" above:


        AGGREGATE OPTION EXERCISES IN YEAR ENDED DECEMBER 31, 1995 AND
                 AGGREGATE OPTION VALUES AT DECEMBER 31, 1995

<TABLE>
<CAPTION>

                                                                         Number of Securities   Value of Unexercised
                                                                             Underlying             In-the-Money
                                                                          Unexercised Options        Options at
                                               Shares                         at 12/31/95             12/31/95
                                              Acquired       Value           (Exercisable/          (Exercisable/
            Name                             On Exercise   Realized(1)       Unexercisable)        Unexercisable(2))
- -----------------------------                -----------   -----------   --------------------   ---------------------
<S>                                          <C>           <C>           <C>                    <C>
Michael F. Connoy............                         --            --      155,001/102,499        $39,150/$19,575

David W. Deetz...............                         --            --        97,000/30,000        $    148,625/$0

James R. Miller..............                         --            --        20,000/80,000        $          0/$0

Barbara E. Roth..............                      7,400     $  43,522        69,683/12,667        $163,305/$1,958

Walter L. Sembrowich, Ph.D...                         --            --            141,500/0        $    194,300/--
- ----------------

(1) Value based on the difference between the fair market value of the share of
    Common Stock on the date of exercise and the exercise price of the options.

(2) Value based on the difference between the fair market value of the shares of
     Common Stock at December 31, 1995 ($4.87) and the exercise price of the
     options.
</TABLE>

                                      -12-
<PAGE>
 
                         COMPARATIVE STOCK PERFORMANCE
                                
     The graph below compares the cumulative total shareholder return on the
Common Stock with the cumulative total return of Standard & Poor's 500 Stock
Index and the Standard & Poor's Medical Products and Supplies Index over the
same period for the period from June 14, 1994 (the date of the initial public
offering of the Common Stock) to December 31, 1995 (assuming the investment in
the Common Stock and each index was $100 on June 14, 1994, and that dividends,
if any, were reinvested).

           COMPARISON OF CUMULATIVE TOTAL RETURN SINCE JUNE 14, 1994
              AMONG DIAMETRICS MEDICAL, INC., S&P 500 STOCK INDEX
                  AND S&P MEDICAL PRODUCTS AND SUPPLIES INDEX


                             [GRAPH APPEARS HERE]

<TABLE>
<CAPTION>
<S>                         <C>       <C>        <C>
                             6/14/94   12/30/94   12/30/95
                             -------   --------   --------

Diametrics Medical, Inc.    $ 100.00  $   87.50  $   81.25
S&P 500 Index                 100.00     101.54     139.70
S&P Medical Products and
   Supplies Index             100.00     115.72     195.58
</TABLE>



                                      -13-
<PAGE>
 
                             CERTAIN TRANSACTIONS

     In February 1995 the Company sold an aggregate of 1,754,635 shares of
Common Stock at a purchase price of $5.50 per share to certain institutional
investors in a private placement.  Of these shares, 454,545 shares were sold to
each of Frazier Healthcare Investments, L.P. ("Frazier") and Allstate Insurance
Company (or entities affiliated therewith) ("Allstate").  In connection with
this private placement and a related letter agreement with each of Frazier and
Allstate, the Company increased its board of directors by two persons, appointed
Dr. Silverstein and Mr. Engbers to serve on the board of directors as
representatives selected by Frazier and Allstate, respectively, and nominated
Dr. Silverstein and Mr. Engbers for election by the shareholders at the Annual
Meeting.  Each of Frazier and Allstate have agreed that, upon the Company's
request, such representatives will not stand for reelection to the board of
directors at the first annual shareholders meeting subsequent to the Company's
receipt of gross proceeds of at least $15,000,000 in a public offering of its
securities.  The Company sold these shares of Common Stock pursuant to purchase
agreements on the same terms as were sold to nonaffiliated purchasers.  Under
these purchase agreements, Frazier and Allstate are entitled to certain
registration rights with respect to their shares.

     Mr. Deetz, Mr. Eibensteiner and Dr. Sembrowich are limited partners of
Medical Innovation Partners II, which is the general partner of Medical
Innovation Fund II, and Mr. Murphy is a limited partner of Medical Innovation
Fund II.  As such limited partners, they have no voting or investment power over
shares of Common Stock held by Medical Innovation Fund II.  Each currently has
less than a 1% economic interest in such shares.

     For a discussion of certain Company transactions with Mr. Eibensteiner,
Mr. Maudlin and Dr. Knudson, see "Executive Compensation--Compensation Committee
Interlocks and Insider Participation" above.

                                      -14-
<PAGE>
 
                            PRINCIPAL SHAREHOLDERS

     The following table sets forth certain information regarding beneficial
ownership of the Common Stock, as of February 28, 1996 by:  (i) each person who
is known by the Company to beneficially own more than 5% of the Common Stock,
(ii) each of the Company's directors and nominees for director, (iii) each of
the officers named under the "Summary Compensation Table" above and (iv) all
directors, nominees and executive officers of the Company as a group:
<TABLE>
<CAPTION>
                                                      NUMBER OF
                                                       SHARES
                                                    BENEFICIALLY
                                                      OWNED (1)      PERCENT (1)
                                                    ------------     ----------
<S>                                                 <C>             <C>
 
Denver Investment Advisors LLC (2)...............     1,520,000         10.2%
  1225 17th Street, 26th Floor
  Denver, Colorado  80202
State of Wisconsin Investment Board (3)..........     1,380,000          9.3
  P.O. Box 7842
  Madison, Wisconsin 53707
Medical Innovation Funds (4).....................     1,241,017          8.1
  Opus Center, Suite 421
  9900 Bren Road East
  Minneapolis, Minnesota 55343
The Allstate Corporation.........................     1,099,328          7.4
  2775 Sanders Road
  Northbrook, Illinois 60062-6127
INVESCO Funds (5)................................       765,775          5.1
  c/o INVESCO plc
  11 Devonshire Square
  London EC2M 4YR
  England
James E. Ashton, Ph.D. (6).......................        16,293           *
Michael F. Connoy (7)............................       155,810          1.0
David W. Deetz (8)...............................       381,269          2.5
Ronald E. Eibensteiner (9).......................       176,207          1.2
William E. Engbers (10)..........................         6,500           *
Mark B. Knudson, Ph.D. (11)......................       162,150          1.1
Ronald A. Matricaria (12)........................         9,000           *
Timothy I. Maudlin (13)..........................            --           --
Walter L. Sembrowich, Ph.D. (14).................       309,497          2.1
Fred E. Silverstein, M.D. (15)...................            --           --
Timothy A. Stepanek (16).........................            --           --
James R. Miller (17).............................        41,456           *
Barbara E. Roth (18).............................        71,604           *
Richard A. Norling...............................            --           --
David T. Giddings................................            --           --
Gerald L. Cohn (20)..............................        92,000           *
Andre de Bruin...................................            --           --
All directors and executive officers as a group
  (15 persons) (19)..............................     1,485,420          9.6
- ----------------
</TABLE>

* Less than 1%.

(Footnotes continued on following pages)

                                      -15-
<PAGE>
 
(1)  Beneficial ownership is determined in accordance with rules of the
     Securities and Exchange Commission, and includes generally voting power
     and/or investment power with respect to securities.  Shares of Common Stock
     subject to options or warrants currently exercisable or exercisable within
     60 days of February 28, 1996 are deemed outstanding for computing the
     percentage of the person holding such options but are not deemed
     outstanding for computing the percentage of any other person.  Except as
     indicated by footnote, the persons named in the table above have sole
     voting and investment power with respect to all shares of Common Stock
     shown as beneficially owned by them.

(2)  In a Schedule 13G Report delivered to the Company as of April 9, 1996,
     Denver Investment Advisors LLC indicated that it decreased its interest in
     the Company to less than 5% of the outstanding shares of Common Stock.

(3)  In a Schedule 13G Report filed with the Securities and Exchange Commission
     in February 1996, the State of Wisconsin Investment Board indicated that it
     had sole voting and dispositive power with respect to all shares listed
     above.

(4)  Includes 818,666 shares of Common Stock held by Medical Innovation Fund and
     81,556 shares of Common Stock held by Medical Innovation Fund II.  Medical
     Innovation Partners and Medical Innovation Partners II are the general
     partners of Medical Innovation Fund and Medical Innovation Fund II,
     respectively.  Also includes 340,795 shares of Common Stock issuable upon
     exercise of outstanding options and warrants.

(5)  In a Schedule 13G Report delivered to the Company dated as of February 14,
     1996, the persons referred to below indicated that:  (a) each of INVESCO
     PLC, INVESCO North American Group, Ltd., INVESCO, Inc., INVESCO North
     American Holdings, Inc. and INVESCO Funds Group, Inc. share voting and
     dispositive power with respect to all of the shares listed above; (b)
     INVESCO PLC, organized under the laws of England, is the parent holding
     company of each of the entities listed above; and (c) INVESCO Funds Group,
     Inc. is an investment adviser registered under Section 203 of the
     Investment Advisers Act of 1940.

(6)  Includes 5,921 shares of Common Stock issuable upon the exercise of
     outstanding options.

(7)  Includes 155,001 shares of Common Stock issuable upon exercise of
     outstanding options and warrants.

(8)  Includes 97,000 shares of Common Stock issuable upon exercise of
     outstanding options and warrants. Excludes approximately 20 shares held by
     Medical Innovation Fund II which Mr. Deetz may be deemed to hold based on
     his limited partnership interest in the general partner of such entity.
     See "Certain Transactions." Mr. Deetz disclaims beneficial ownership of
     such shares.

(9)  Includes 12,375 shares of Common Stock issuable upon exercise of
     outstanding options.  Excludes approximately 20 shares held by Medical
     Innovation Fund II which Mr. Eibensteiner may be deemed to hold based on
     his limited partnership interest in the general partner of such entity.
     See "Certain Transactions."  Mr. Eibensteiner disclaims beneficial
     ownership of such shares.

(10) Includes 6,500 shares of Common Stock issuable upon the exercise of
     outstanding options and warrants.

                                      -16-
<PAGE>
 
(11) Includes 9,900 shares of Common Stock issuable upon the exercise of
     outstanding options.  Excludes an aggregate of 1,241,017 shares held by
     Medical Innovation Fund and Medical Innovation Fund II, of which Dr.
     Knudson is a limited partner and a general partner, respectively, of the
     general partner of each such partnership.  See Note 2 above.  Dr. Knudson
     disclaims beneficial ownership of such shares.

(12) Includes 9,000 shares of Common Stock issuable upon exercise of outstanding
     options and warrants.

(13) Excludes an aggregate of 1,241,017 shares held by Medical Innovation Fund
     and Medical Innovation Fund II, of which Mr. Maudlin is a general partner
     of the general partner of each such partnership.  See Note 2 above.  Mr.
     Maudlin disclaims beneficial ownership of such shares.

(14) Includes 142,897 shares of Common Stock issuable upon exercise of
     outstanding options and warrants.  Excludes approximately 20 shares held by
     Medical Innovation Fund II which Dr. Sembrowich may be deemed to hold based
     on his limited partnership interest in the general partner of such entity.
     See "Certain Transactions."  Dr. Sembrowich disclaims beneficial ownership
     of such shares.

(15) Excludes an aggregate of 461,045 shares held by Frazier Healthcare
     Investments, L.P.  The General Partner of Frazier Healthcare Investments,
     L.P., is Frazier Healthcare Management, L.P., whose General Partner is
     Frazier & Company L.P., whose  General Partner is Frazier Management L.L.C.
     Silverstein Capital, Inc., of which Dr. Silverstein is a shareholder, is a
     member of Frazier Management L.L.C.  Dr. Silverstein disclaims beneficial
     ownership of such shares.

(16) Excludes an aggregate of 578,843 shares held by Parsnip River Company, of
     which Mr. Stepanek is a general partner.  See Note 5 above.  Mr. Stepanek
     disclaims beneficial ownership of such shares.

(17) Includes 40,000 shares of Common Stock issuable upon the exercise of
     outstanding options and warrants.

(18) Includes 69,683 shares of Common Stock issuable upon the exercise of
     outstanding options and warrants.

(19) See Notes 5, 6, 8, 9, 10, 11, 12, 13, 14, 15 and 16 above.  Includes an
     additional 49,744 shares of Common Stock issuable upon exercise of
     outstanding options and warrants.  Does not include approximately 347
     additional shares held by Medical Innovation Fund II which Mr. Travis L.
     Murphy may be deemed to hold based on his limited partnership interest in
     such entity.  See "Certain Transactions."  Mr. Murphy disclaims beneficial
     ownership of such shares.

(20) Includes 12,000 shares held in the Hanna S. Cohn and Samuel A. Cohn
     Memorial Foundation, with respect to which Mr. Cohn disclaims beneficial
     ownership.

                                      -17-
<PAGE>
 
           ITEM 2:  CLASSIFIED BOARD AMENDMENT TO BYLAWS AND RELATED
         AMENDMENTS  TO BYLAWS AND RESTATED ARTICLES OF INCORPORATION

GENERAL

     The Board of Directors has determined that the amendment of Sections 3.02,
3.09 and 3.10 of Article III of the Company's Bylaws and the addition of an
Article VIII to its Restated Articles of Incorporation (the "Amendments") are
advisable and recommends their adoption at the Annual Meeting.  The proposed
amendments to Article III of the Bylaws would establish a classified Board of
Directors and staggered terms for directors and the requirement of an
affirmative vote by the holders of 80% of the outstanding shares of Common Stock
(an "80% Shareholder Vote") to increase or decrease the size of the Board and to
remove directors.  The new Article VIII of the Restated Articles of
Incorporation would require an 80% Shareholder Vote to amend or repeal Bylaws
fixing the number of directors or their classifications, qualifications or terms
of office, or containing procedures for removing directors or filling vacancies
in the Board.  Article VIII would also provide for an 80% Shareholder Vote to
increase or decrease the size of the Board and remove directors.  In addition,
Article VIII would require an 80% Shareholder Vote to approve a proposal to
amend or repeal Article VIII unless such proposal has been approved by the
"Continuing Directors" (as defined), in which case the vote is reduced to a
majority of the outstanding shares.  These changes are being presented to
shareholders for their approval as a single proposal.  The purpose of the
Amendments is to provide for continuity and stability of management by
staggering terms for which directors are elected, and to make it more difficult
for a substantial shareholder to change abruptly the entire Board of Directors
of the Company without the approval and cooperation of the incumbent Board.

     There has been a recent trend toward the accumulation of substantial stock
positions in public corporations as a prelude to proposing a takeover or a
restructuring or sale of all or part of the corporation or other similar
extraordinary corporate action.  Such actions are often undertaken without
advance notice to or consultation with management of the corporation.  In many
cases, the purchaser seeks representation on the corporation's board of
directors in order to increase the likelihood that its proposal will be
implemented by the corporation.  If the corporation resists the efforts of the
purchaser to obtain representation on its board, the purchaser may commence a
proxy contest to have its nominees elected to the board in place of certain
directors or the entire board.  In some cases, the purchaser may not truly be
interested in taking over the corporation but uses the threat of a proxy fight
or bid to take over the corporation as a means of forcing the corporation to
repurchase its equity position at a substantial premium over the then current
market price.

     The Board of Directors of the Company believes that any imminent threat of
removal of the Company's management in a proxy fight would severely curtail
management's ability to negotiate effectively with potential purchasers.
Management would be deprived of the time necessary to collect information and
evaluate the takeover proposal, to study alternative proposals and to help
ensure that the best price is obtained in any transaction involving the Company
which may ultimately be undertaken.  The Amendments will help ensure that the
Board will have sufficient time to review a proposal made by a third party which
has acquired a significant block of the Company's Common Stock and to evaluate
appropriate alternatives to the proposal.  The Amendments are intended to
encourage persons seeking to acquire control of the Company to initiate such an
acquisition through arms' length negotiations with the Company's management and
Board of Directors, who would then be in a position to negotiate a transaction
which is fair to all shareholders.

     The submission of the Amendments for shareholder approval is not being made
in response to any specific effort of which the Company is aware to accumulate
the Company's Common Stock or to obtain control of the Company.

                                      -18-
<PAGE>
 
     The Board of Directors does not believe that the Restated Articles of
Incorporation or the Bylaws currently contain any provisions which should be
viewed as anti-takeover devices.  Under the Restated Articles of Incorporation,
however, the shareholders have authorized 20,000,000 shares of Common Stock, of
which 4,876,605 shares were unissued and unreserved as of April 30, 1996.  Such
authorized and unissued shares could be used, by private placement or otherwise,
without the need for any action by the shareholders, in one or more transactions
which could make more difficult, discourage or thwart attempts by third parties
to gain control of the Company if the Board of Directors did not approve such
attempted takeover.  In addition, certain corporations have recently issued
warrants to acquire common stock as a dividend to the holders of their common
stock with terms designed to discourage or defeat acquisition proposals, which
may serve to deter third parties from making of offers to acquire the
corporation without the approval of the board of directors.  The Board of
Directors is currently considering using a portion of the authorized and
unissued Common Stock for this purpose, but has taken no formal action with
respect to adopting such an anti-takeover measure.

     The Amendments may significantly affect the ability of shareholders of the
Company to effect rapid changes in the composition of the Board of Directors.
Accordingly, before voting, shareholders are urged to read carefully the
following description of the Amendments and their purposes and effects.  The
text of the proposed Bylaw amendments is set forth in full as Exhibit A hereto.
The text of proposed Article VIII to the Restated Articles of Incorporation is
set forth in full as Exhibit B hereto.

DESCRIPTION OF AMENDMENTS TO BYLAWS

     The amendment to Section 3.02 of Article III of the Bylaws would provide
for the eventual election of all directors for three-year rather than one-year
terms, with approximately one-third of the directors to be elected each year.
Under the amendment, the seven directors to be elected at the Annual Meeting in
1996 will be divided into three classes, with two directors to be elected for
terms expiring in 1997, two directors to be elected for terms expiring in 1998
and three directors to be elected for terms expiring in 1999.  Commencing in
1997 and thereafter, all directors, except as described below, would be elected
to three-year terms.

     The proposed amendment to Section 3.02 of Article III of the Bylaws states
that the number of directors shall be no less than three nor more than twenty
and that such number shall be established by resolution of the Board of
Directors.  The amendment would provide that holders of 80% of the outstanding
shares of Common Stock would have the authority to increase or decrease the size
of the Board.  If the size of the Board were altered, the increase or decrease
would be distributed among the three classes of directors as equally as
possible, as determined by the Board or by an 80% Shareholder Vote.  Under the
Bylaws, the Board can also elect a director to fill a vacancy created by an
increase in the size of the Board or fill any vacancy created by the death,
resignation, retirement, disqualification or removal of a director.  Any such
director would have to stand for reelection at the next Annual Meeting of
Shareholders for his or her then unexpired term.  Presently, the Bylaws provide
that directors shall hold office until the next Annual Meeting and do not
contain any special voting requirements for increasing or decreasing the number
of directors.

     The proposed amendment to Section 3.09 of Article III of the Bylaws is
intended to clarify the procedures for filling vacancies in the Board and to
conform the language of Section 3.09 to the amendment effected by the proposed
amendment to Section 3.02.

     The proposed amendment to Section 3.10 of Article III of the Bylaws would
provide that directors may be removed from office, with or without cause, only
by an 80% Shareholder Vote.  

                                      -19-
<PAGE>
 
Currently, Section 3.10 provides that removal may be effected by majority
affirmative vote of the shares entitled to vote at an election of directors.

DESCRIPTION OF ARTICLE VIII OF THE RESTATED ARTICLES OF INCORPORATION

     In order to make the proposed amendments to the Bylaws effective, the Board
also recommends the addition of a new Article VIII to the Restated Articles of
Incorporation.  Article VIII provides that the Board of Directors shall have the
power, to the extent permitted by law, to adopt, amend or repeal the Bylaws,
subject to the power of the shareholders to adopt, amend or repeal them.  Under
Minnesota law, the Board may not adopt, amend or repeal Bylaws fixing a quorum
for meetings of shareholders prescribing procedures for removing directors or
filling vacancies in the Board, or fixing the number of directors or their
classifications, qualifications or terms of office, but may adopt or amend
Bylaws to increase the number of directors.

     Article VIII would impose the 80% Shareholder Vote requirement for the
adoption, amendment or repeal of Bylaws fixing the number of directors or their
classifications, qualifications or terms of office, or containing procedures for
removing directors or filling vacancies in the Board.  Article VIII would also
require an 80% Shareholder Vote to increase or decrease the size of the Board or
remove directors.  Such provisions of Article VIII are needed because, under
Minnesota law, requirements for shareholder votes greater than a majority must
be set forth in the Restated Articles of Incorporation to be effective.  The
Bylaws currently provide that they may be repealed or amended by a majority of
the whole Board of Directors, subject to the power of the shareholders,
exercisable in the manner provided under Minnesota law, to adopt, amend or
repeal the Bylaws adopted, amended or repealed by the Board of Directors.

     Article VIII would also require an 80% Shareholder Vote to approve a
proposal to amend or repeal Article VIII unless such proposal has been approved
by the Continuing Directors, in which case the vote is reduced to a majority of
the outstanding shares.  Continuing Director is defined to mean any director who
is unaffiliated with a "Controlling Person" (as defined) and was director prior
to the time the Controlling Person became a Controlling Person, and any
successor of a Continuing Director who is unaffiliated with a Controlling Person
and is recommended or elected to succeed a Continuing Director by a majority of
the Continuing Directors.  The term Controlling Person is defined to mean any
individual or any corporation, partnership and other entity which beneficially
owns in excess of 10% of the outstanding shares of Common Stock.

PURPOSE AND EFFECTS OF THE AMENDMENTS

     The classification of directors is intended to make it more difficult to
change the composition of the Board of Directors.  At least two shareholders'
meetings, instead of one, will generally be required for shareholders to effect
a change in control of the Board.  Although the Company has not encountered any
lack of continuity or stability, the Board believes that a longer period of time
being required to elect a majority of the directors will help assure continuity
and stability of the Company's affairs and policies in the future as a majority
of the directors at any given time will have prior experience as directors of
the Company.  The classification provision will apply to every election of
directors, whether or not a change in the composition of the Board, in the
opinion of some or a majority of the Company's shareholders, would be desirable.

     The provisions of the proposed amendments to Section 3.10 of Article III
and the Restated Articles of Incorporation relating to the removal of directors
are designed to protect the classified Board structure in the event a third
party gains control of a majority of the Company's outstanding Common Stock.
The requirement of an 80% Shareholder Vote to remove directors, together with
the 

                                      -20-
<PAGE>
 
provision of Section 3.09 that vacancies on the Board of Directors may be
filled by the directors, are intended to preclude such third party from removing
incumbent directors and simultaneously gaining control of the Board by filling
the vacancies created by removal.  Moreover, the currently existing provision
that newly created directorships are to be filled by the Board, along with the
amendments to Section 3.02 of Article III and the Restated Articles of
Incorporation that provide for Board action or an 80% Shareholder Vote to
increase the size of the Board of Directors, would prevent those seeking
majority representation on the Board of Directors from obtaining such
representation simply by enlarging the Board and filling the new directorships
created thereby with their own nominees.

     The requirement of an 80% Shareholder Vote to effect amendment or repeal of
Sections 3.02, 3.09 or 3.10 of Article III of the Bylaws or Article VIII of the
Restated Articles of Incorporation will prevent a takeover bidder or other
shareholder holding a majority (but less than 80%) of the Common Stock from
avoiding the requirements of the Amendments by simply repealing them.  However,
such requirement may give minority shareholders veto power over any changes in
the Amendments, unless the Continuing Directors approve such changes.

     The Amendments may make more difficult or discourage a proxy contest, the
removal of the incumbent Board or the assumption of control of the Company, by
tender offer or otherwise, by a third party, even though such action might be
beneficial to the Company and its shareholders, and could thus increase the
likelihood that incumbent directors will retain their positions.  Under the
Amendments, a shareholder or shareholders controlling a majority, but less than
80%, of the outstanding Common Stock of the Company would be unable to remove
directors without the approval of some of the shareholders holding the balance
of the Common Stock.  In addition, since the Amendments are designed in part to
discourage accumulations of large blocks of the Company's Common Stock by
purchasers whose objective is to have such stock repurchased by the Company at a
premium, adoption of the amendments could tend to reduce the temporary
fluctuations in the market price of the Company's Common Stock which could be
caused by accumulations of large blocks of Common Stock.  Accordingly,
shareholders could be deprived of possible opportunities to sell their Common
Stock at a temporarily higher market price.

     Takeovers or changes in the management of the Company proposed and effected
without prior consultation and negotiation with the Board would not necessarily
be detrimental to the Company and its shareholders.  However, the Board believes
that the benefits of seeking to protect its ability to negotiate with the
proponent of an unfriendly or unsolicited proposal to take over or restructure
the Company outweigh the disadvantages of discouraging such proposals.

VOTE REQUIRED FOR ADOPTION OF THE AMENDMENTS

     The affirmative vote of the holders of a majority of the shares of Common
Stock present and entitled to vote on the Amendments at the Annual Meeting is
required to adopt this proposal.  THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR"
THE ADOPTION OF THE AMENDMENTS.


                 ITEM 3:  PROPOSAL TO AMEND STOCK OPTION PLAN

     The Board of Directors has approved, subject to shareholder approval, an
amendment to the Stock Option Plan to increase the number of shares of Common
Stock available for issuance thereunder from 1,740,000 shares to 3,000,000
shares.  As of December 31, 1995, the Company had outstanding options to
purchase an aggregate of 1,450,188 shares, at a weighted average exercise price
of $4.66 per share, pursuant to the Stock Option Plan.  The Board of Directors
believes that the Stock Option Plan has been and continues to be an important
incentive in attracting, retaining and motivating key 

                                      -21-
<PAGE>
 
employees, and that it is appropriate to increase the number of shares available
for option grants and other awards under the Stock Option Plan at this time.
Approval of the proposed amendment to increase the number of authorized shares
under the Stock Option Plan will assure that sufficient shares are available to
enable the Committee to achieve the objectives of the Stock Option Plan to aid
in maintaining and developing personnel capable of assuring the future success
of the Company, to offer such personnel additional incentives to put forth
maximum effort for the success of the business and to afford them an opportunity
to acquire an interest in the Company through stock options.

     Pursuant to the Stock Option Plan, executive officers, other employees and
consultants of the Company may receive options to purchase Common Stock.  The
Stock Option Plan was approved by the Board of Directors in June 1990, amended
in July 1992 and June 1993 and approved by the Company's shareholders in June
1993.  The Stock Option Plan provides for the grant of both incentive stock
options ("ISOs") intended to qualify for preferential tax treatment under
Section 422 of the Internal Revenue Code of 1986, as amended, and nonqualified
stock options that do not qualify for such treatment.  The exercise price of all
options granted under the Stock Option Plan must equal or exceed the fair market
value of the Common Stock at the time of grant.  The Stock Option Plan also
provides for grants of stock appreciation rights ("SARs"), restricted stock
awards and performance awards.  Only employees are eligible for the grant of
incentive stock options.  The Stock Option Plan is administered by the
Compensation Committee; however, the Compensation Committee may delegate to the
Chief Executive Officer of the Company the right to grant awards with respect to
participants who are not subject to Section 16(b) of the Securities Exchange Act
of 1934.

     The following is a summary of the principal federal income tax consequences
generally applicable to options and awards under the Stock Option Plan.  The
grant of an option or SAR will result in no tax consequences for the recipient
or the Company or any subsidiary employing such individual (the "employer").
The holder of an ISO generally will have no taxable income upon exercising the
ISO (except that the alternative minimum tax may apply), and the employer
generally will receive no tax deduction when an ISO is exercised.  Upon exercise
of a stock option other than an ISO, the optionee must recognize ordinary income
equal to the excess of the fair market value of the shares acquired on the date
of exercise over the option price, and the employer will then be entitled to a
tax deduction for the same amount.  The tax consequences to an optionee of a
disposition of shares acquired through the exercise of an option will depend on
how long the shares have been held and upon whether such shares were acquired by
exercising an ISO or stock option other than an ISO.  Generally, there will be
no tax consequence to the employer in connection with a disposition of shares
acquired under an option except that the employer may be entitled to a tax
deduction in the case of a disposition of shares acquired under an ISO before
the applicable ISO holding period has been satisfied.

     With respect to other awards granted under the Plan that are settled either
in cash, shares or other property that is either transferable or not subject to
a substantial risk of forfeiture, the holder of an award must recognize ordinary
income equal to the excess of (a) the cash or the fair market value of the
shares or other property received (determined as of the date of such settlement)
over (b) the amount (if any) paid for such shares or other property by the
holder of the award, and the employer will then be entitled to a deduction for
the same amount.  With respect to awards that are settled in shares or other
property that is restricted as to transferability and subject to a substantial
risk of forfeiture, unless a special tax election is made to recognize ordinary
income upon receipt of the awards, the holder of the award must recognize
ordinary income equal to the excess of (i) the fair market value of the shares
or other property received (determined as of the first time the shares or other
property become transferable or not subject to a substantial risk of forfeiture,
whichever occurs earlier) over (ii) the amount (if any) paid by the participant
for such shares or other property, and the employer will then be entitled to a
deduction for the same amount.

                                      -22-
<PAGE>
 
     Special rules apply in the case of individuals subject to Section 16(b) of
the Securities Exchange Act of 1934.  In particular, under current law, shares
received pursuant to the exercise of a stock option, other purchase right, or
SAR may be treated as restricted as to transferability and subject to a
substantial risk of forfeiture for a period of up to six months after the date
of exercise.  Accordingly, unless a special tax election is made, the amount of
ordinary income recognized and the amount of the employer's deduction may be
determined as of such date.

     As of April 30, 1996, there were outstanding options to purchase an
aggregate of 1,392,595 shares of Common Stock under the Stock Option Plan as
follows:  Michael F. Connoy, 287,500 shares; Dennis J. McFadden, 80,000 shares;
James R. Miller, 100,000 shares; Travis L. Murphy, 43,000 shares; Barbara E.
Roth, 10,000 shares; Walter L. Sembrowich, Ph.D., 141,500 shares; all executive
officers as a group, 662,000 shares; and all employees (excluding executive
officers) as a group, 730,595 shares.  No options have been granted or are
expected to be granted to directors who are not also executive officers under
the Stock Option Plan, except for the grant to Dr. Knudson of an option to
purchase 14,500 shares of Common Stock as described above under "Election of
Directors--Director Compensation." An aggregate of 38,900 shares of Common Stock
have been awarded under the Stock Option Plan as performance awards pursuant to
the Company's Stock Bonus Program described above under "Executive Compensation-
- -Executive Compensation Program--Stock Bonus Program."  Future grants of options
and awards to executive officers and other employees under the Stock Option Plan
are not determinable.

     The affirmative vote of a majority of the shares of Common Stock
represented at the meeting is required for the approval of the amendment to the
Stock Option Plan.  THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE AMENDMENT
TO THE STOCK OPTION PLAN.


                  ITEM 4:  PROPOSAL TO AMEND DIRECTORS' PLAN

     The Board of Directors has approved an amendment to the Directors' Plan to
increase the number of shares of Common Stock subject to the Initial Grant of
options thereunder from 10,000 shares to 14,500 shares and the number of shares
of Common Stock subject to the Subsequent Grants of options thereunder from
1,500 shares to 4,000 shares, subject to shareholder approval.  Based on a
review of similar plans of other public companies, the Board of Directors
believes that an increase in the number of shares subject to the Initial Grant
of options and the Subsequent Grants of options under the Directors' Plan is
consistent with the plans of other public companies and is desirable at this
time in order to attract qualified individuals to serve as the Company's
directors.
 
     The Directors' Plan is designed to operate automatically and not to require
administration; however, to the extent administration is necessary, it will be
provided by the Board of Directors.  Only non-employee directors are eligible to
participate in the Directors' Plan.  In the event of a merger in which the
Company is not the surviving corporation, a transfer of all of the Company's
stock, a sale of substantially all of the Company's assets or a dissolution or
liquidation of the Company, all outstanding options will become exercisable in
full at least ten days prior to such event on such conditions as the Board shall
determine, unless the successor corporation assumes the outstanding options or
substitutes substantially equivalent options.

     The following is a summary of the principal federal income tax consequences
generally applicable to options and awards under the Directors' Plan.  The grant
of an option under the Director's Plan is not expected to result in any taxable
income for the recipient.  Upon exercising a non-qualified stock option, the
optionee must recognize ordinary income equal to the excess of the fair market
value of the shares of Common Stock acquired on the date of exercise over the
exercise price, and the Company will be entitled at that time to a tax deduction
for the same amount.  The tax consequence to a director 

                                      -23-
<PAGE>
 
upon a disposition of shares acquired through the exercise of a non-qualified
option granted under the Director's Plan will depend upon how long the shares
have been held. Generally, there will be no tax consequence to the Company in
connection with the disposition of shares acquired pursuant to such an option.

     Special rules apply to directors under Section 16(b) of the Exchange Act.
Under certain circumstances, shares received pursuant to the exercise of a stock
option may be deemed restricted under the Code for a period of up to six months
after the date of exercise resulting in the amount of any ordinary income
recognized, and the amount of the Company's tax deduction, being determined as
of the end of such period instead of on the date of exercise.

     Additional information concerning the Directors' Plan is set forth above
under "Election of Directors-Director Compensation."

     The affirmative vote of a majority of the shares of Common Stock
represented at the meeting is required for the approval of the amendment to the
Directors' Plan.  THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE AMENDMENT
TO THE DIRECTORS' PLAN.


                ITEM 5:  PROPOSAL TO AMEND STOCK PURCHASE PLAN

     The Board of Directors has approved an amendment to the 1995 Employee Stock
Purchase Plan (the "Stock Purchase Plan") to increase the number of shares of
Common Stock available for issuance thereunder from 150,000 shares to 300,000
shares, subject to shareholder approval.  Of the 150,000 shares currently
authorized for issuance pursuant to the Stock Purchase Plan, 94,622 shares are
available to the Company for future issuance.  The Board of Directors believes
that an increase in the authorized shares under the Stock Purchase Plan is
desirable to allow continued employee ownership participation in the Company for
the next several years.

     The Stock Purchase Plan was originally approved by the Board of Directors
in April 1995 and by the shareholders of the Company in June 1995.  The purpose
of the Stock Purchase Plan is to provide employees of the Company with an
opportunity to share in the ownership of the Company by providing them with a
convenient means for regular and systematic purchases of Common Stock, and,
thus, to develop a stronger incentive to work for the continued success of the
Company.  The Stock Purchase Plan is intended to qualify under Section 423 of
the Code.

     Under the Stock Purchase Plan, an eligible employee (including executive
officers of the Company) may purchase shares of Common Stock from the Company
through payroll deductions of up to 10% of their base compensation at a price
per share equal to 85% of the lesser of the fair market value (based on the
Nasdaq/NMS closing price) of the Company's Common Stock as of the first day or
the last day of each three-month offering period under the Stock Purchase Plan.
The offering periods will commence on January 1, April 1, July 1 and October 1
of each year.  The first purchase period commenced on July 1, 1995.

     The Stock Purchase Plan is administered by the Company's Compensation
Committee.  All questions of interpretation of the Stock Purchase Plan will be
determined by the Committee.  Any employee who is customarily employed for at
least 20 hours per week by the Company, and who does not own five percent or
more of the total combined voting power or value of all classes of the Company's
outstanding capital stock, is eligible to participate in the Stock Purchase
Plan, provided that the employee has been employed for at least 90 days prior to
the commencement date of an offering period.

                                      -24-
<PAGE>
 
     The maximum number of shares that a participant may purchase on the last
day of any offering period is determined by dividing the participant's payroll
deductions accumulated during the offering period by the purchase price.
However, no person may purchase shares under this or any other employee stock
purchase plan of the Company to the extent that purchases pursuant to such
employee stock purchase plans accrue a right to purchase shares at a rate that
exceeds $25,000 worth of stock (determined based on fair market value of the
shares on the first day of the offering period) for any calendar year and no
more than 2,000 shares may be purchased under the Stock Purchase Plan by any
participant during any purchase period.

     Payroll deductions under the Stock Purchase Plan will be reportable by a
participant as a part of the participant's income for the year in which such
amounts would otherwise have been paid.  The participant will not have any
additional taxable income at the time shares are purchased under the Stock
Purchase Plan, even though the purchase will be made for less than fair market
value.  A participant may have taxable income in the year in which a sale or
other disposition of the purchased shares is made, depending upon the
circumstances.  Generally, there will be no tax consequences to the Company in
connection with the issuance of shares under the Stock Purchase Plan, except
that the Company may be entitled to a tax deduction in the case of a
participant's disposition of shares acquired under the Stock Purchase Plan
before the applicable holding period for tax purposes has been satisfied.

     An aggregate of 55,378 shares have been issued under the Stock Purchase
Plan as follows:  Michael F. Connoy, 609 shares; James R. Miller, 1,256 shares;
Dennis J. McFadden, 501 shares; Travis L. Murphy, 89 shares; all executive
officers as a group, 2,455 shares; and all employees (excluding executive
officers) as a group, 52,923 shares.  Other than Michael F. Connoy, no director
has purchased shares under the Stock Purchase Plan.  The number of shares which
may be purchased in the future under the Stock Purchase Plan is not
determinable.

     The affirmative vote of a majority of the shares of Common Stock
represented at the meeting is required for the approval of the amendment to the
Stock Purchase Plan.  THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE
AMENDMENT TO THE STOCK PURCHASE PLAN.


          ITEM 6:  PROPOSAL TO APPROVE DIRECTORS' EQUALIZING OPTIONS

     As a result of the 1.45-for-one stock split of the Company's Common Stock
in June 1993, the Initial Grants under the Directors' Plan made prior to that
date were adjusted such that Initial Grants of options to purchase 10,000 shares
became options to purchase 14,500 shares of Common Stock pursuant to the terms
of the Directors' Plan and such options.  In addition, subject to shareholder
approval, the Directors' Plan has been amended such that directors joining the
Company after August 1995 have received or will receive an Initial Grant of
options to purchase 14,500 shares.  However, outside directors joining the Board
of Directors after the date of the stock split but prior to the date of the
amendment have received an Initial Grant of options to purchase 10,000 shares of
Common Stock.  In order to equalize the number of options granted to each of the
Company's outside directors, the Compensation Committee and the Board of
Directors approved the additional one-time grant of options (the "Directors'
Equalizing Options") to purchase 4,500 shares of Common Stock at an exercise
price of $9.75 per share (the fair market value on the date of grant) to each of
Messrs. Engbers and Matricaria and Dr. Silverstein.  Such options terminate on
June 29, 2005, vest with respect to 50% of such shares on June 29, 1996 and vest
with respect to an additional 25% of such shares on June 29, 1997 and June 29,
1998, respectively.  The Directors' Equalizing Options are subject to
shareholder approval.  See "Proposal to Approve Directors' Equalizing Options."

                                      -25-
<PAGE>
 
     The affirmative vote of a majority of the shares of Common Stock
represented at the meeting is required for the approval of the Directors'
Equalizing Options. THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE APPROVAL
OF THE DIRECTORS' EQUALIZING OPTIONS.


                       COMPLIANCE WITH SECTION 16(A) OF
                      THE SECURITIES EXCHANGE ACT OF 1934

     Section 16(a) of the Securities Exchange Act of 1934, as amended, requires
the Company's directors and executive officers, and persons who own more than
ten percent of a registered class of the Company's equity securities, to file
with the Securities and Exchange Commission initial reports of ownership and
reports of changes in ownership of common stock and other equity securities of
the Company. Officers, directors and greater-than ten percent shareholders are
also required by SEC regulation to furnish the Company with copies of all
Section 16(a) forms they file.

     To the Company's knowledge, based solely on review of the copies of such
reports furnished to the Company and written representations that no other
reports were required, during the fiscal year ended December 31, 1995 all
Section 16(a) filing requirements applicable to its officers, directors and
greater than ten-percent beneficial owners were satisfied.


                      APPOINTMENT OF INDEPENDENT AUDITORS

     The Board of Directors has appointed KPMG Peat Marwick LLP as independent
auditors for the Company for the fiscal year ending December 31, 1996. KPMG Peat
Marwick LLP has served as the Company's independent auditors since 1990 and has
no relationship with the Company other than that arising from its employment as
independent auditors. Representatives of KPMG Peat Marwick LLP are expected to
be present at the Annual Meeting, will have an opportunity to make a statement
if they desire to do so, and will be available to respond to appropriate
questions from shareholders.


                     PROPOSALS FOR THE NEXT ANNUAL MEETING
    
     Any proposal by a shareholder to be presented at the next Annual Meeting
must be received at the Company's principal executive offices, 2658 Patton Road,
Roseville, Minnesota 55113, no later than January 21, 1997.


                                BY ORDER OF THE BOARD OF DIRECTORS
 

                                /s/ Kenneth L. Cutler

                                Kenneth L. Cutler
                                Secretary



May 20, 1996     

                                      -26-
<PAGE>
 
                                                                       EXHIBIT A

                             AMENDMENTS TO BYLAWS


               AMENDED SECTION 3.02 OF ARTICLE III OF THE BYLAWS

     SECTION 3.02.  Number, Qualification and Term of Office.  The number of
directors shall be no less than three nor more than twenty and shall be
established by resolution of the Board of Directors.  Directors need not be
shareholders.  The number of directors may be increased or decreased from time
to time by a resolution adopted by the affirmative vote of the holders of at
least 80% of the outstanding shares of common stock, par value $.01 per share
(the "Common Stock"), of the corporation entitled to vote.  The directors shall
be divided into three classes, as equal in number as possible.  At the 1996
regular meeting of the shareholders:

          (i)    directors in the first class (currently two directors) shall be
     elected to serve until the 1997 regular meeting of shareholders,

          (ii)   directors in the second class (currently two directors) shall
     be elected to serve until the 1998 regular meeting of the shareholders, and

          (iii)  directors in the third class (currently three directors) shall
     be elected to serve until the 1999 regular meeting of the shareholders;

or until their successors shall be duly elected and qualified.  At each regular
meeting of the shareholders following the 1996 regular shareholders' meeting,
each director elected to succeed a director whose term has expired shall hold
office until the third succeeding regular meeting of the shareholders after such
director's election and until such director's successor has been duly elected
and qualified, or until the earlier death, resignation, removal or
disqualification of such director.  In case of any increase or decrease in the
number of directors, the increase or decrease shall be distributed among the
several classes as equally as possible as shall be determined by the Board of
Directors or by the affirmative vote of the holders of at least 80% of the
outstanding shares of Common Stock entitled to vote.

               AMENDED SECTION 3.09 OF ARTICLE III OF THE BYLAWS

     SECTION 3.09.  Vacancies.  Vacancies in the Board of Directors of this
corporation occurring by reason of death, resignation, removal or
disqualification shall be filled for the unexpired term by a majority of the
remaining directors, even though less than a quorum.  Vacancies resulting from
an increase in the number of directors may be filled by a majority vote of the
remaining directors.  Each director elected to fill a vacancy shall hold office,
subject to the provisions of these Bylaws, until a qualified successor is
elected by the shareholders at a regular or special meeting.  The shareholders
shall elect a director to fill the remainder of any unexpired term for which a
director has been elected to fill a vacancy by the Board of Directors at their
next regular or special meeting.

               AMENDED SECTION 3.10 OF ARTICLE III OF THE BYLAWS

     SECTION 3.10.  Removal.  The affirmative vote of the shareholders holding
at least 80% of the outstanding shares of Common Stock entitled to vote at an
election of directors may remove any or all of the directors from office at any
time, with or without cause.  In the event that the Board of Directors or any
one or more directors be so removed, new directors shall be elected at the same
meeting.  

                                      A-1
<PAGE>
 
A director named by the Board of Directors to fill a vacancy may be removed from
office at any time, with or without cause, by the affirmative vote of the
remaining directors if the shareholders have not elected directors in the
interim between the time of the appointment to fill such vacancy and the time of
the removal.

                                      A-2
<PAGE>
 
                                                                       EXHIBIT B

                            NEW ARTICLE VIII OF THE
                      RESTATED ARTICLES OF INCORPORATION


                                 ARTICLE VIII

     The Board of Directors shall have the power, to the extent permitted by
law, to adopt, amend or repeal the Bylaws of this corporation, subject to the
power of the shareholders to adopt, amend or repeal such Bylaws.  Bylaws fixing
the number of directors or their classifications, qualifications or terms of
office, or prescribing procedures for removing directors or filling vacancies in
the Board may be adopted, amended or repealed only by the affirmative vote of
the holders of 80% of the outstanding shares of Common Stock entitled to vote.

     The number of directors shall be no less than three nor more than twenty
and shall be established by resolution of the Board of Directors.  The number of
directors may be increased or decreased from time to time by a resolution
adopted by the holders of at least 80% of the outstanding shares of Common Stock
entitled to vote.  In case of any increase or decrease in the number of
directors, the increase or decrease shall be distributed among the several
classes of directors as equally as possible as shall be determined by the Board
of Directors or by the holders of at least 80% of the outstanding shares of
Common Stock entitled to vote.  The affirmative vote of shareholders holding at
least 80% of the outstanding shares of Common Stock entitled to vote at an
election of directors may remove any or all of the directors from office at any
time, with or without cause.

     Notwithstanding any other provisions of these Restated Articles of
Incorporation or the Bylaws of the corporation or the fact that a lesser
percentage may be specified by law, these Restated Articles of Incorporation or
the Bylaws of the corporation, the affirmative vote of the holders of at least
80% of outstanding shares of Common Stock entitled to vote shall be required to
amend or repeal all or any portion of this Article VIII; provided, however, that
if the Continuing Directors shall be majority vote of all Continuing Directors
have adopted a resolution approving the amendment or repeal proposal and have
determined to recommend it for approval by the holders of Common Stock, then the
vote required shall be the affirmative vote of the holders of at least a
majority of the outstanding Common Stock entitled to vote.

     The term "Common Stock" shall mean the Common Stock, par value $.01 per
share, of the corporation.

     The term "Continuing Director" shall mean any member of the Board of
Directors of the corporation who is unaffiliated with a Controlling Person and
was a member of the Board prior to the time that the Controlling Person became a
Controlling Person, and any successor of a Continuing Director who is
unaffiliated with a Controlling Person and is recommended or elected to succeed
a Continuing Director by a majority of all Continuing Directors.

     The term "Controlling Person" shall mean any Person who beneficially owns a
number of shares of Common Stock, whether or not such number includes shares not
then issued, which exceeds a number equal to ten percent of the outstanding
shares of Common Stock.

     The term "Person" shall mean an individual, a corporation, a partnership,
an association, a joint-stock company, a trust, any unincorporated organization
and any other entity or group.

                                      B-1
<PAGE>
 
PROXY

                            DIAMETRICS MEDICAL, INC.
                                2658 PATTON ROAD
                           ROSEVILLE, MINNESOTA 55113

             NOTICE OF ANNUAL MEETING OF SHAREHOLDERS JUNE 27, 1996

          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
    
  The undersigned appoints Michael F. Connoy and Dennis J. McFadden, and each
of them, with power to act without the other and with all the right of
substitution in each, the proxies of the undersigned to vote all shares of
Diametrics Medical, Inc. (the "Company") held by the undersigned on April 29,
1996, at the Annual Meeting of Shareholders of the Company, to be held on
Thursday, June 27, 1996, at 3:30 p.m., at the Minneapolis Hilton, 1001
Marquette Avenue, Minneapolis, Minnesota, and all adjournments thereof, with
all powers the undersigned would possess if present in person. All previous
proxies given with respect to the meeting are revoked.      

  Receipt of Notice of Annual Meeting of Shareholders and Proxy Statement is
acknowledged by your execution of this proxy. Complete, sign, date, and return
this proxy in the addressed envelope--no postage required. Please mail promptly
to save further solicitation expenses.

1. Election of directors:      
   [_] FOR all nominees listed below (except as marked to the contrary below).
   [_] WITHHOLD AUTHORITY to vote for all nominees listed below.

Nominees: James E. Ashton, Ph.D., Fred E. Silverstein, M.D., Gerald L. Cohn,
          Mark B. Knudson, Ph.D., David T. Giddings, Andre de Bruin, Richard A.
          Norling

(Instruction: To withhold authority for any individual nominee, write that
nominee's name in the space provided below.)

- --------------------------------------------------------------------------------
2. Proposal to approve an amendment to the Company's Bylaws providing for a
   classified Board of Directors and to approve certain other related amendments
   to the Bylaws and Restated Articles of Incorporation of the Company.
   
   [_] FOR     [_] AGAINST     [_] ABSTAIN

3. Proposal to approve an amendment to the Company's 1990 Stock Option Plan.

   [_] FOR     [_] AGAINST     [_] ABSTAIN

             (continued, and to be dated and signed, on other side)

4. Proposal to approve an amendment to the Company's 1993 Directors' Stock
   Option Plan.

   [_] FOR     [_] AGAINST     [_] ABSTAIN

5. Proposal to approve an amendment to the Company's 1995 Employee Stock
   Purchase Plan.

   [_] FOR     [_] AGAINST     [_] ABSTAIN

6. Proposal to approve the Company's 1995 Directors' Equalizing Options.

   [_] FOR     [_] AGAINST     [_] ABSTAIN

7. To vote with discretionary authority upon such other matters as may come
   before the meeting.

  THIS PROXY, WHEN PROPERLY EXECUTED, WILL BE VOTED IN THE MANNER DIRECTED
HEREIN BY THE UNDERSIGNED SHAREHOLDER. IF NO DIRECTION IS PROVIDED BY THE
UNDERSIGNED SHAREHOLDER, THIS PROXY WILL BE VOTED "FOR" ITEMS 1, 2, 3, 4, 5 AND
6 LISTED HEREIN. UPON ALL OTHER MATTERS, THE PROXIES SHALL VOTE AS THEY DEEM IN
THE BEST INTERESTS OF THE COMPANY.
 
                                           SIGNATURE(S)
 
                                           ------------------------------------
 
                                           ------------------------------------
 
                                           Dated: _______________________, 1996

                                           INSTRUCTION: When shares are held
                                           by joint tenants, all joint tenants
                                           should sign. When signing as attor-
                                           ney, executor, administrator,
                                           trustee, custodian, or guardian,
                                           please give full title as such. If
                                           shares are held by a corporation,
                                           this proxy should be signed in full
                                           corporate name by its president or
                                           other authorized officer. If a
                                           partnership holds the shares sub-
                                           ject to this proxy, an authorized
                                           person should sign in the name of
                                           such partnership.


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