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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. 2)*
GeneMedicine, Inc.
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(Name of Issuer)
Common Stock, $.001 par value
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(Title of Class of Securities)
368707105
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(CUSIP Number)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
Page 1 of 5 Pages
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CUSIP NO. 368707105 13G PAGE 2 OF 5 PAGES
- ----------------------- ---------------------
- ------------------------------------------------------------------------------
NAME OF REPORTING PERSON
1 I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Abingworth Bioventures SICAV
- ------------------------------------------------------------------------------
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
2 (a) [_]
(b) [_]
- ------------------------------------------------------------------------------
SEC USE ONLY
3
- ------------------------------------------------------------------------------
CITIZENSHIP OR PLACE OF ORGANIZATION
4
Luxembourg
- ------------------------------------------------------------------------------
SOLE VOTING POWER
5
NUMBER OF 987,144
SHARES -----------------------------------------------------------
SHARED VOTING POWER
BENEFICIALLY 6
- 0 -
OWNED BY
-----------------------------------------------------------
EACH SOLE DISPOSITIVE POWER
7
REPORTING 987,144
PERSON -----------------------------------------------------------
SHARED DISPOSITIVE POWER
WITH 8
- 0 -
- ------------------------------------------------------------------------------
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
9
987,144 shares
- ------------------------------------------------------------------------------
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10
[_]
- ------------------------------------------------------------------------------
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11
7.1%
- ------------------------------------------------------------------------------
TYPE OF REPORTING PERSON*
12
CO
- ------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 2 of 5 pages
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Item 1(a). Name of Issuer: GeneMedicine, Inc.
- ---------- --------------
Item 1(b). Address of Issuer's Principal Executive Offices:
- ---------- -----------------------------------------------
8301 New Trails Drive, The Woodlands, Texas 77381-4248
Item 2(a). Name of Person Filing: Abingworth Bioventures SICAV ("ABS")
- ---------- ---------------------
Item 2(b). Address of Principal Business Office or, if None, Residence: The
- ---------- -----------------------------------------------------------
address of the principal business office of ABS is 231 Val des Bons
Malades, L-2121 Luxembourg-Kirchberg.
Item 2(c). Citizenship: ABS is a corporation organized under the laws of
- ---------- -----------
Luxembourg.
Item 2(d). Title of Class of Securities: Common Stock, $.001 par value.
- ---------- ----------------------------
Item 2(e). CUSIP Number: 368707105
- ---------- -------------
Item 3. If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b),
- ------- -------------------------------------------------------------------
check whether the person filing is a:
------------------------------------
(a) [ ] Broker or Dealer registered under Section 15 of the
Securities Exchange Act of 1934 (the "Act").
(b) [ ] Bank as defined in Section 3(a)(6) of the Act.
(c) [ ] Insurance Company as defined in Section 3(a)(19) of
the Act.
(d) [ ] Investment Company registered under Section 8 of the
Investment Company Act of 1940.
(e) [ ] Investment Adviser registered under Section 203 of
the Investment Advisers Act of 1940.
(f) [ ] Employee Benefit Plan, Pension Fund which is subject
to the provisions of the Employee Retirement Income
Security Act of 1974 or Endowment Fund; see Rule 13d-
1(b)(1)(ii)(F) of the Act.
(g) [ ] Parent Holding Company, in accordance with Rule 13d-
1(b)(ii)(G) of the Act.
(h) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(H) of
the Act.
Not applicable. This statement on Schedule 13G is not filed
pursuant to Rule 13d-1(b) or Rule 13d-2(b).
Page 3 of 5 pages
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Item 4. Ownership.
----------
(a) Amount Beneficially Owned: ABS is the record and beneficial
owner of 987,144 shares of Common Stock as of December 31, 1997.
(b) Percent of Class: 7.1%. The foregoing percentage is calculated
based on the 13,831,309 shares of Common Stock reported to be
outstanding in the Quarterly Report on Form 10-Q of GeneMedicine,
Inc. for the quarter ended September 30, 1997.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
987,144 shares.
(ii) shared power to vote or to direct the vote:
0 shares.
(iii) sole power to dispose or to direct the disposition of:
987,144 shares.
(iv) shared power to dispose or to direct the disposition of:
0 shares.
Item 5. Ownership of Five Percent or Less of a Class.
- ------- ---------------------------------------------
Not applicable.
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
- ------- ---------------------------------------------------------------
Not applicable.
Item 7. Identification and Classification of the Subsidiary Which Acquired the
- ------- ----------------------------------------------------------------------
Security Being Reported on by the Parent Holding Company.
--------------------------------------------------------
Not applicable.
Item 8. Identification and Classification of Members of the Group.
- ------- ---------------------------------------------------------
Not applicable
Item 9. Notice of Dissolution of Group.
- ------- ------------------------------
Not applicable.
Item 10. Certification.
- -------- -------------
Not applicable. This statement on Schedule 13G is not filed pursuant
to Rule 13d-1(b).
Page 4 of 5 pages
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SIGNATURE
After reasonable inquiry and to the best of its knowledge and belief, the
undersigned certifies that the information set forth in this statement is true,
complete and correct.
Date: February 13, 1998
ABINGWORTH BIOVENTURES SICAV
By: /s/Karl U. SANNE
----------------
Name: Karl U. SANNE
Title: Director
--------
By: /s/Fernand HEIM
---------------
Name: Fernand HEIM
Title: Mandatory
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Page 5 of 5 pages
