INSURED MUNICIPALS INCOME TRUST 243RD INSURED MULTI SERIES
497J, 2000-02-28
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                            February 26, 2000



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

Attn:  Filing Desk - Stop 1-4

     Re:  Insured Municipals Income Trust-Insured Multi-Series 243
          File No. 333-64261   CIK #896602

Ladies/Gentlemen:

         In accordance with the provisions of Rule 497(j) of Regulation C under
the Securities Act of 1933 (the "Securities Act") this letter serves to certify
that the most recent amendment to the Post-Effective of the subject Registration
Statement on Form S-6 for the above captioned Trust does not differ from that
which would have been filed pursuant to Rule 497(b) of the Securities Act.
Amendment No. 1 to the Post-Effective, which was the most recent amendment to
the Post-Effective of the Registration Statement, was filed electronically with
the Commission on February 23, 2000.

                                    Very truly yours,




                                    Van Kampen Funds Inc.


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