INSURED MUNICIPALS INC TR & INV QUAL TAX EX TR MULTI SER 249
485BPOS, 1995-04-19
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                   Contents of Registration Statement
  
  This Amendment of Registration Statement comprises the following papers
  and documents:

      The facing sheet and
      The consents of independent public accountants, ratings services
      and legal counsel
  
  The following exhibits:
  
  1.1   Copy of Trust Agreement.
  
  1.4   Copy of Municipal Bond Investment Trust Insurance Policy issued by
        AMBAC Indemnity Corporation Company and/or Financial Guaranty
        Insurance Company for each Insured Trust.
  
  1.5   Form of Master Agreement Among Underwriters.
  
  3.1   Opinion and consent of counsel as to legality of securities being
        registered.
  
  3.2   Opinion of counsel as to the Federal, Colorado, Florida and
        Virginia income tax status of securities being registered.
  
  3.3   Opinion and consent of counsel as to New York income tax status of
        the Fund under New York law.
  
  3.4   Opinion and consent of counsel as to income tax status to
        Massachusetts residents of Units of the Massachusetts IM-IT Trust.
  
  4.1   Consent of Interactive Data Services, Inc.
  
  4.2   Consent of Standard & Poor's Ratings Group with respect to the
        Insured Trusts.
  
  4.3   Consent of Grant Thornton LLP.
  
  4.4   Financial Data Schedule.
                               Signatures
     
     The  Registrant,  Insured  Municipals Income  Trust  and  Investors'
Quality  Tax-Exempt  Trust, Multi-Series 249, hereby  identifies  Insured
Municipals  Income Trust and Investors' Quality Tax-Exempt Trust,  Multi-
Series  189  and  Multi-Series 213 for purposes  of  the  representations
required by Rule 487 and represents the following: (1) that the portfolio
securities  deposited in the series as to the securities  of  which  this
Registration Statement is being filed do not differ materially in type or
quality from those deposited in such previous series; (2) that, except to
the  extent  necessary  to  identify the  specific  portfolio  securities
deposited  in,  and to provide essential financial information  for,  the
series  with  respect  to  the  securities  of  which  this  Registration
Statement  is being filed, this Registration Statement does  not  contain
disclosures  that differ in any material respect from those contained  in
the  registration statements for such previous series  as  to  which  the
effective  date  was determined by the Commission or the staff;  and  (3)
that it has complied with Rule 460 under the Securities Act of 1933.
     
     Pursuant  to  the requirements of the Securities Act  of  1933,  the
Registrant,  Insured Municipals Income Trust and Investors' Quality  Tax-
Exempt  Trust,  Multi-Series 249 has duly caused this  Amendment  to  the
Registration  Statement to be signed on its behalf  by  the  undersigned,
thereunto  duly authorized, in the City of Chicago and State of  Illinois
on the 18th day of April, 1995.

                                    Insured Municipals Income Trust and
                                       Investors' Quality Tax-Exempt
                                       Trust, Multi-Series 249
                                    
                                    
                                    
                                    By Sandra A. Waterworth
                                       Vice President
     
     Pursuant  to  the requirements of the Securities Act of  1933,  this
Amendment  to  the Registration Statement has been signed  below  by  the
following persons, in the capacities indicated on April 18, 1995.

 Signature               Title

Don G. Powell         Chariman and Chief Exeutive
                        Officer

William R. Rybak      Senior Vice President and       )
                        Chief Financial Officer       )

Ronald A. Nyberg      Director                        )

William R. Molinari   Director

Sandra A. Waterworth
(Attorney-in-fact*)



* A copy of each of the related powers of attorney was
  filed with the Securities and Exchange Commission in connection with
  the Registration Statement on Form S-6 of Insured Municipals Income
  Trust and Investors' Quality Tax-Exempt Trust, Multi-Series 203 (File
  No. 33-65744) and with the Registration Statement on From S-6 of
  Insured Municipals Income Trust, 170th Insured Multi-Series (File No.
  33-55891) and the same are hereby incorporated herein by this
  reference.


                                                            Exhibit 1.1
                                   --
                   Insured Municipals Income Trust and
                   Investors' Quality Tax-Exempt Trust
                            Multi-Series 249
                                    
                             Trust Agreement
                                    
                                                  Dated: April 18, 1995
     
     This  Trust  Agreement between Van Kampen  American  Capital
Distributors, Inc., as Depositor, American Portfolio Evaluation Services,
a division of Van Kampen American Capital Investment Advisory Corp., as
Evaluator, and The Bank of New York, as Trustee, sets forth certain
provisions in full and incorporates other provisions by reference to the
document entitled "Standard Terms and Conditions of Trust For Van Kampen
American Capital Distributors, Inc. Tax-Exempt Trust, Dated March 16,
1995" (herein called the "Standard Terms and Conditions of Trust"), and
such provisions as are set forth in full and such provisions as are
incorporated by reference constitute a single instrument.  All references
herein to Articles and Sections are to Articles and Sections of the
Standard Terms and Conditions of Trust.
                                    
                            Witnesseth That:
     
     In consideration of the premises and of the mutual agreements herein
contained, the Depositor and the Trustee agree as follows:
                                    
                                 Part I
                                    
                 Standard Terms and Conditions of Trust
     
     Subject to the provisions of Part II hereof, all the provisions
contained in the Standard Terms and Conditions of Trust are herein
incorporated by reference in their entirety and shall be deemed to be a
part of this instrument as fully and to the same extent as though said
provisions had been set forth in full in this instrument.
                                    
                                 Part II
                                    
                  Special Terms and Conditions of Trust
     
     The following special terms and conditions are hereby agreed to:
     
          (a)    The  Bonds  defined in Section 1.01(4),  listed  in  the
     Schedules hereto, have been deposited in the Trusts under this Trust
     Agreement.
     
          (b)   The fractional undivided interest in and ownership of the
     various  Trusts represented by each Unit thereof is the  amount  set
     forth  under  "Summary of Essential Financial Information-Fractional
     Undivided Interest in the Trust per Unit" in the Prospectus.
     
          (c)    The approximate amounts, if any, which the Trustee shall
     be  required to advance out of its own funds and cause to be paid to
     the  Depositor pursuant to Section 3.05 shall be the amount per Unit
     that the Trustee agreed to reduce its fee or pay Trust expenses  set
     forth  in the footnotes to the "Per Unit Information" for each Trust
     in  the  Prospectus times the number of units in such Trust referred
     to in Part II (b) of this Trust Agreement.
     
         (d)   The First General Record Date and the amount of the second
     distribution of funds from the Interest Account of each Trust  shall
     be the record date for the Interest Account and the amount set forth
     under "Per Unit Information" for each Trust in the Prospectus.
     
          (e)    The  First Settlement Date shall be the date  set  forth
     under  "Summary of Essential Financial Information-First  Settlement
     Date" in the Prospectus.
     
          (f)    Any monies held to purchase "when issued" bonds will  be
     held in noninterest bearing accounts.
     
          (g)    The  Evaluation Time for purpose of  sale,  purchase  or
     redemption of Units shall be 4:00 P.M. Eastern time.
     
          (h)    As  set  forth  in Section 3.05, the  Record  Dates  and
     Distribution Dates for each Trust are those dates set forth  in  the
     section entitled "Per Unit Information" for each Trust as appears in
     the Prospectus.
     
          (i)    As  set  forth  in Section 3.15, the Evaluator's  Annual
     Supervisory  Fee  shall  be that amount set  forth  in  "Summary  of
     Essential Financial Information-Evaluator's Annual Supervisory  Fee"
     in the Prospectus.
     
          (j)    As  set  forth  in Section 4.03, the Evaluator's  Annual
     Evaluation Fee shall be that amount, and computed on that basis, set
     forth  in  "Summary  of  Essential Financial Information-Evaluator's
     Annual Evaluation Fee" in the Prospectus.
     
          (k)    the  Trustee's annual compensation as  set  forth  under
     Section  6.04, under each distribution plan shall be that amount  as
     specified  in  the Prospectus under the section entitled  "Per  Unit
     Information" for each Trust.
     
     In  Witness Whereof, Van Kampen American Capital Distributors,  Inc.
has  caused  this  Trust Agreement to be executed  by  one  of  its  Vice
Presidents  or  Assistant Vice Presidents and its corporate  seal  to  be
hereto  affixed  and  attested  by its  Secretary  or  one  of  its  Vice
Presidents   or  Assistant  Secretaries,  American  Portfolio  Evaluation
Services,  a division of Van Kampen American Capital Investment  Advisory
Corp.,  has  caused this Trust Indenture and Agreement to be executed  by
its President or one of its Vice Presidents and its corporate seal to  be
hereto  affixed and attested to by its Secretary, its Assistant Secretary
or  one  of  its Assistant Vice Presidents and The Bank of New York,  has
caused  this Trust Agreement to be executed by one of its Vice Presidents
and its corporate seal to be hereto affixed and attested to by one of its
Vice  Presidents, Assistant Vice Presidents or Assistant Treasurers;  all
as of the day, month and year first above written.

                                    VAN KAMPEN AMERICAN CAPITAL
                                       DISTRIBUTORS, INC., Depositor


                                    By Sandra A. Waterworth
                                       Vice President
[Seal]
Attest:



By Gina M. Scumaci
   Assistant Secretary

                                    American Portfolio Evaluation
                                       Services a division of Van Kampen
                                       American Capital Investment
                                       Advisory Corp.
                                    
                                    
                                    By Dennis J. Mcdonnell
                                       President
[Seal]
Attest:



By Scott E. Martin
   Secretary

                                    The Bank Of New York
                                    
                                    
                                    By Jeffrey Bieselin
                                       Vice President
[Seal]
Attest:



By Norbert Loney
   Assistant Treasurer 

                      Schedules to Trust Agreement
                                    
                     Securities Initially Deposited
                                    
                   Insured Municipals Income Trust and
                   Investors' Quality Tax-Exempt Trust
                                    
                            Multi-Series 249    

(Note:   Incorporated  herein and made a part hereof as  indicated  below
         are  the corresponding "Portfolios" of each of the Trusts as set
         forth in the Prospectus.)



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