VAN KAMPEN AMERICAN CAPITAL EQUITY OPPORTUNITY TR SER 16
24F-2NT, 1996-09-27
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U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549 

FORM 24F-2 
Annual Notice of Securities Sold 
Pursuant to Rule 24f-2 



1. Name and address of issuer:  Van Kampen American Capital Equity 
                                  Opportunity Trust, Series 16
                                One Parkview Plaza
                                Oakbrook Terrace, IL 60181


2. Name of each series or class of funds for which this notice is filed: 

   Van Kampen American Capital Equity Opportunity Trust, Series 16


3. Investment Company Act File Number: 811-2754

   Securities Act File Number: 33-61507


4. Last day of fiscal year for which this notice is filed: September 17, 1996


5. Check box if this notice is being filed more than 180 days after the 
close of the issuer's fiscal year for purposes of reporting securities sold 
after the close of the fiscal year but before termination of the issuer's 
24f-2 declaration:     [    ] 


6. Date of termination of issuer's declaration under rule 24f-2(a)(1), if
applicable (see Instruction A.6): 


7. Number and amount of securities of the same class or series which had been
registered under the Securities Act of 1933 other than pursuant to rule 24f-2
in a prior fiscal year, but which remained unsold at the beginning of the
fiscal year:       - 0 -


8. Number and amount of securities registered during the year other than
pursuant to rule 24f-2:       - 0 -


9.Number and aggregate sale price of securities sold during the fiscal year: 

              2,335,460                $29,698,973


10.Number and aggregate sale price of securities issued during the fiscal year
in reliance upon registration pursuant to rule 24f-2:

              2,335,460                $29,698,973


11.Number and aggregate sale price of securities issued during the fiscal year
in connection with dividend reinvestment plans, if applicable (see Instruction
B.7):     - 0 -





    



<TABLE>
<CAPTION>
12.      Calculation of registration fee:                                                                                          
<S>      <C>                                                                                                         <C>           
(i)      Aggregate sale price of securities sold during the fiscal year in reliance on rule 24f-2 (from Item 10):    $   29,698,973
                                                                                                                     --------------
         Aggregate price of shares issued in connection with dividend reinvestment plans (from Item 11, if                         
(ii)     applicable):                                                                                                +        - 0 -
                                                                                                                     --------------
(iii)    Aggregate price of shares redeemed or repurchased during the fiscal year (if applicable):                   -    3,334,323
                                                                                                                     --------------
         Aggregate price of shares redeemed or repurchased and previously applied as a reduction to filing fees                   
(iv)     pursuant to rule 24e-2 (if applicable):                                                                     +        - 0 -
                                                                                                                     --------------
         Net aggregate price of securities sold and issued during the fiscal year in reliance on rule 24f-2 [line                 
(v)      (i), plus line (ii), less line (iii), plus line (iv)] (if applicable):                                          26,364,650
                                                                                                                     --------------
         Multiplier prescribed by Section 6(b) of the Securities Act of 1933 or other applicable law or regulation                 
(vi)     (see Instruction C.6):                                                                                      x       1/2900
                                                                                                                     --------------
(vii)    Fee due [line (i) or line (v) multiplied by line (vi)]:                                                     $        9,091
                                                                                                                     ==============
- -----------------------------------------------------------------------------------------------------------------------------------
</TABLE>


 

Instruction:Issuers should complete lines (ii), (iii), (iv) and (v) only if
the form is being filed within 60 days after the close of the issuer's fiscal
year. See Instruction C.3. 


13.Check box if fees are being remitted to the Commission's lockbox depository
as described in section 3a of the Commission's Rules of Informal and Other
Procedures (17 CFR 202.3a).        [ x ] 


Date of mailing or wire transfer of filing fees to the Commission's lockbox
depository:   08/29/96




SIGNATURES

This report has been signed below by the following persons on behalf of the
issuer and in the capacities and on the dates indicated. 



By (Signature and Title)*  /s/Sandy A. Waterworth

                              Sandy A. Waterworth
                              Vice President



Date: 09/27/96

        *Please print the name and title of the signing officer below the
signature. 



                           CHAPMAN AND CUTLER
                         111 West Monroe Street
                        Chicago, Illinois  60603


                           September 27, 1996



Van Kampen American Capital Distributors, Inc.
One Parkview Plaza
Oakbrook Terrace, Illinois  60181


     Re:              Van Kampen American Capital
            Equity Opportunity Trust, Series 16 (the "Trust")

Gentlemen:
     
     We   have   served  as  counsel  for  Van  Kampen  American  Capital
Distributors, Inc. ("Van Kampen"), as Sponsor and Depositor of the  Trust
in  connection with the preparation, execution and delivery  of  a  Trust
Indenture  and  Agreement for the above-captioned  series  of  which  Van
Kampen  is Depositor and Bank of New York is Trustee, pursuant  to  which
the  Depositor has delivered to and deposited Bonds listed in Schedule  A
to  the  Trust Indenture and Agreement with the Trustee and  pursuant  to
which  the  Trustee  has issued to or on the order  of  the  Depositor  a
certificate or certificates representing an aggregate number of Units  of
fractional undivided interest in and ownership of the Trust created under
said Trust Indenture and Agreement.
     
     In connection therewith, we have examined such pertinent records and
documents  and  matters of law as we have deemed necessary  in  order  to
enable us to express the opinions hereinafter set forth.
     
     Based   upon  the  foregoing,  we  are  of  the  opinion  that   the
certificates  evidencing  the Units in the  Trust  constitute  valid  and
binding obligations of the Trust in accordance with the terms thereof.

                                    Very truly yours,



                                    CHAPMAN AND CUTLER
MJK/cjw



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