VAN KAMPEN AMERICAN CAPITAL INSURED INCOME TRUST SER 49, 497J, 2000-11-29

VAN KAMPEN AMERICAN CAPITAL INSURED INCOME TRUST SER 49
497J, 2000-11-29

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                            November 29, 2000



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

Attn:  Filing Desk - Stop 1-4

 Re:  Van Kampen American Capital Insured Income Trust (Intermediate), Series 48
      Van Kampen American Capital Insured Income Trust, Series 49
      File No. 33-61319   CIK #897160

Ladies/Gentlemen:

         In accordance with the provisions of Rule 497(j) of Regulation C under
the Securities Act of 1933 (the "Securities Act") this letter serves to certify
that the most recent amendment to the Post-Effective of the subject Registration
Statement on Form S-6 for the above captioned Trust does not differ from that
which would have been filed pursuant to Rule 497(b) of the Securities Act. The
most recent amendment to the Registration Statement was filed electronically
with the commission on November 22, 2000.

                                    Very truly yours,




                                    Van Kampen Funds Inc.