HOLLIS EDEN PHARMACEUTICALS INC /DE/
SC 13G, 1998-02-12
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                                 UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C.  20549


                                  SCHEDULE 13G

                   UNDER THE SECURITIES EXCHANGE ACT OF 1934
                            
                            (AMENDMENT NO.      )*  
                                           -----


                       Hollis Eden Pharmaceuticals, Inc.
         -------------------------------------------------------------
                                (Name of Issuer)

                                 Common Stock
              ---------------------------------------------------
                        (Title of Class of Securities)

                                  435902101 
                   -----------------------------------------
                                 (CUSIP Number)


Check the following box if a fee is being paid with this statement [_]. (A fee
is not required only if the filing person: (1) has a previous statement on file
reporting beneficial ownership of more than five percent of the class of
securities described in Item 1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of five percent or less of such class.)
(See Rule 13d-7).

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).


                              Page 1 of 12 Pages

<PAGE>

- -----------------------                                  ---------------------
  CUSIP NO. 435902101                   13G               PAGE 2 OF 12 PAGES
- -----------------------                                  ---------------------
 
- ------------------------------------------------------------------------------
      NAME OF REPORTING PERSON
 1    I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
      Strome Susskind Investment Management, L.P.
      95-4450882  

- ------------------------------------------------------------------------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2                                                              (a) [_]
                                                                (b) [_]
                                                 
- ------------------------------------------------------------------------------
      SEC USE ONLY
 3
 

- ------------------------------------------------------------------------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4    
      Delaware 

- ------------------------------------------------------------------------------
                          SOLE VOTING POWER
                     5   
     NUMBER OF            
 
      SHARES       -----------------------------------------------------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                          356,578
     OWNED BY
                   -----------------------------------------------------------
       EACH               SOLE DISPOSITIVE POWER
                     7    
    REPORTING             
 
      PERSON       -----------------------------------------------------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                          356,578
- ------------------------------------------------------------------------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9  
      356,578

- ------------------------------------------------------------------------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10                  
                                                                    [_]
 
- ------------------------------------------------------------------------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11    
      5.3%

- ------------------------------------------------------------------------------
      TYPE OF REPORTING PERSON*
12
      PN, IA

- ------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>

- -----------------------                                  ---------------------
  CUSIP NO. 435902101                   13G               PAGE 3 OF 12 PAGES
- -----------------------                                  ---------------------
 
- ------------------------------------------------------------------------------
      NAME OF REPORTING PERSON
 1    I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
      SSCO, Inc.
      95-4450883  

- ------------------------------------------------------------------------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2                                                              (a) [_]
                                                                (b) [_]
                                                 
- ------------------------------------------------------------------------------
      SEC USE ONLY
 3
 

- ------------------------------------------------------------------------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4    
      Delaware 

- ------------------------------------------------------------------------------
                          SOLE VOTING POWER
                     5   
     NUMBER OF            
 
      SHARES       -----------------------------------------------------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                          356,578
     OWNED BY
                   -----------------------------------------------------------
       EACH               SOLE DISPOSITIVE POWER
                     7    
    REPORTING             
 
      PERSON       -----------------------------------------------------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                          356,578
- ------------------------------------------------------------------------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9  
      356,578

- ------------------------------------------------------------------------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10                  
                                                                    [_]
 
- ------------------------------------------------------------------------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11    
      5.3%

- ------------------------------------------------------------------------------
      TYPE OF REPORTING PERSON*
12
      CO, HC

- ------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!



<PAGE>

- -----------------------                                  ---------------------
  CUSIP NO. 435902101                   13G               PAGE 4 OF 12 PAGES
- -----------------------                                  ---------------------
 
- ------------------------------------------------------------------------------
      NAME OF REPORTING PERSON
 1    I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
      Mark E. Strome
      ###-##-####  

- ------------------------------------------------------------------------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
 2                                                              (a) [_]
                                                                (b) [_]
                                                 
- ------------------------------------------------------------------------------
      SEC USE ONLY
 3
 

- ------------------------------------------------------------------------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4    
      United States

- ------------------------------------------------------------------------------
                          SOLE VOTING POWER
                     5   
     NUMBER OF            
 
      SHARES       -----------------------------------------------------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                          356,578
     OWNED BY
                   -----------------------------------------------------------
       EACH               SOLE DISPOSITIVE POWER
                     7    
    REPORTING             
 
      PERSON       -----------------------------------------------------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                          356,578
- ------------------------------------------------------------------------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9  
      356,578

- ------------------------------------------------------------------------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
10                  
                                                                    [_]
 
- ------------------------------------------------------------------------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11    
      5.3%

- ------------------------------------------------------------------------------
      TYPE OF REPORTING PERSON*
12
      IN, HC

- ------------------------------------------------------------------------------

                     *SEE INSTRUCTIONS BEFORE FILLING OUT!



<PAGE>
 
                                                                    Page 5 of 12

Item 1 (a)   Name of Issuer:

             Hollis-Eden Pharmaceuticals, Inc.

Item 1 (b)   Address of Issuer's Principal Executive Offices:

             9333 Genesee Avenue, Suite 110
             San Diego, CA 92121

Item 2 (a)   Name of Person Filing:  This statement is being filed by:

             a.   Strome-Susskind Investment Management, L.P. ("SSIM")

             b.   SSCO, Inc. ("SSCO"); and

             c.   Mark E. Strome ("Strome")
 
             collectively the "Reporting Persons".

             SSIM is a Delaware limited partnership and a registered investment
             adviser. SSIM is the sole general partner of and investment adviser
             to two investment limited partnerships that directly own shares of
             common stock of Hollis-Eden Pharmaceuticals, Inc. (the "Stock").
             SSIM is also the investment adviser to two offshore investment
             corporations that directly own shares of the Stock.

             SSCO is the sole general partner of SSIM. The Mark E. Strome Living
             Trust, dated 01/16/97 (the "Trust") is the controlling shareholder
             of SSCO. Mark E. Strome is the settlor and a trustee of the Trust.

             SSIM's beneficial ownership of the Stock is direct because of its
             general partnership interests in the investment limited
             partnerships that directly own shares of the Stock. SSIM also has
             direct beneficial ownership of the Stock as a result of its
             discretionary authority to buy, sell and vote shares of such Stock
             for its investment advisory clients (i.e., the investment limited
             partnerships and the investment corporations (collectively referred
             to hereinafter as the "Entities")). SSCO's and Strome's beneficial
             ownership are indirect as a result of their ownership of SSIM, and
             is reported solely because Rule 13d-1(a) and (b) promulgated under
             the Securities Exchange Act of 1934, as amended, requires any
             person who is "directly or indirectly" the beneficial owner of more
             than five percent of any equity security of a specific class to
             file a Schedule 13G within the specific time period. The answers on
             blocks 6, 8, 9 and 11 on pages 3 and 4 above and in response to
             item 4 by SSCO and Strome are given on the basis of the
<PAGE>
 
                                                                    Page 6 of 12


             "indirect" beneficial ownership referred to in such Rule, based on
             the direct beneficial ownership of the Stock by SSIM and the
             relationship of SSCO and Strome to SSIM.

             Information with respect to each Reporting Person is given solely
             by the respective Reporting Person, and no Reporting Person
             undertakes hereby any responsibility for the accuracy or
             completeness of such information concerning any other Reporting
             Person.

Item 2 (b)   Address of Principal Business Office or, if none, Residence:


 
             a.  100 Wilshire Blvd., 15th Fl. Santa Monica, CA 90401

 
             b.  100 Wilshire Blvd., 15th Fl. Santa Monica, CA 90401
 
             c.  100 Wilshire Blvd., 15th Fl. Santa Monica, CA 90401

Item 2 (c)   Citizenship:

             a.  Strome-Susskind Investment Management, L.P.; Delaware limited
                 partnership
 
             b.  SSCO, Inc.; Delaware corporation

             c.  Mark E. Strome; United States
 
Item 2 (d)   Title of Class of Securities:

             Common Stock

Item 2 (e)   CUSIP Number:

             435902101

Item 3.      Statement Concerning Filings Pursuant to Rule 13d-1(b) or 13d-2(b):

             (e)  x  Investment Adviser
                  -                    
             (g)  x  Parent Holding Company [controlling shareholders] [See 
                  -      
                     Item 7]
<PAGE>
 
                                                                    Page 7 of 12


Item 4.      Ownership:

             (a)  Amount Beneficially Owned: Reporting Persons each directly or
             indirectly beneficially own 356,578 shares of Stock. The Entities'
             and SSIM's beneficial ownership is direct and SSCO's and Strome's
             beneficial ownership is indirect.

             (b)  Percent of Class: 5.3%

             (c)  Number of shares as to which such person has:
 
             (i)  sole power to vote or to direct the vote: 0

             (ii) shared power to vote or to direct the vote:

             The Reporting Persons share with each other the power to vote all
             356,578 shares of Stock for which they have direct or indirect
             beneficial ownership. No other person has the power to vote such
             shares.

             (iii) sole power to dispose or to direct the disposition of: 0

             (iv) shared power to dispose or to direct the disposition of:

             The Reporting Persons share with each other the power to dispose of
             all 356,578 shares for which they have direct or indirect
             beneficial ownership. They do not share this power with any other
             person.

Item 5.      Ownership of Five Percent or Less of a Class:

             Not Applicable

Item 6.      Ownership of More than Five Percent on Behalf of Another Person:

             SSIM, a registered investment adviser, SSCO, its general partner
             and Strome, the trustee of SSCO's controlling shareholder, have the
             right or the power to direct the receipt of dividends from the
             Stock, and to direct the receipt of proceeds from the sale of Stock
             to SSIM's investment advisory clients. No single investment
             advisory client of SSIM owns more the 5% of the Stock.
             
Item 7.      Identification and Classification of the Subsidiary Which Acquired
             the Security Being Reported on by the Parent Holding Company.

 
<PAGE>
 
                                                                    Page 8 of 12


             SSCO and Strome are each considered the equivalent of a parent
             holding company for purposes of this Schedule 13G. SSIM, a
             registered investment adviser, is considered SSCO's and Strome's
             subsidiary. See Exhibit B.

Item 8.      Identification and Classification of Members of the Group:

             Not Applicable

Item 9.      Notice of Dissolution of Group:

             Not Applicable

Item 10.     Certification:

             By signing below I certify that, to the best of my knowledge and
             belief, the securities referred to above were acquired in the
             ordinary course of business and were not acquired for the purpose
             of and do not have the effect of changing or influencing the
             control of the issuer of such securities and were not acquired in
             connection with or as a participant in any transaction having such
             purposes or effect.

             After reasonable inquiry and to the best of my knowledge and
             belief, I certify that the information set forth in this statement
             is true, complete and correct.


             /s/ Jeffrey S. Lambert
             ------------------------------ 
             Mark E. Strome

 
             STROME SUSSKIND INVESTMENT MANAGEMENT, L.P.
             By SSCO, Inc., its General Partner
 
             By: /s/ Jeffrey S. Lambert
                -------------------------------------------
                Jeffrey S. Lambert, Chief Financial Officer

             SSCO, INC.
 
             By: /s/ Jeffrey S. Lambert
                -------------------------------------------
                Jeffrey S. Lambert, Chief Financial Officer

             Date: 02/11/98
                  -------------------------- 
<PAGE>
 
                                                                    Page 9 of 12

                                    EXHIBITS


EXHIBIT A    Power of Attorney Granted by Mark E. Strome

EXHIBIT B    Statement With Respect to Joint Filing of Schedule 13G

EXHIBIT C    Identification and Classification of Subsidiary Which Acquired
             Security Being Reported On By the Parent Holding Company

<PAGE>
 
                                                                   Page 10 of 12

                                   Exhibit A

                          POWER OF ATTORNEY FORMS FOR
                       SCHEDULES 13D AND 13G AND FORM 13F


     I, Mark E. Strome in my individual capacity and as a principal of Strome
     Susskind Investment Management, L.P., hereby appoint Jeffrey S. Lambert as
     attorney-in-fact and agent, in all capacities, to execute, on my behalf and
     on behalf of Strome Susskind Investment Management, L.P. and to file with
     the appropriate issuers, exchanges and regulatory authorities, any and all
     Schedules 13D and 13G and Forms 13F and documents relating thereto required
     to be filed under the Securities Exchange Act of 1934, including exhibits,
     attachments and amendments thereto and request for confidential information
     contained therein.  I hereby grant to said attorney-in-fact full authority
     to do every act necessary to be done in order to effectuate the same as
     fully, to all intents and purposes, as I could if personally present,
     thereby ratifying all that said attorneys-in-fact and agents may lawfully
     do or cause to be done by virtue hereof.

     I hereby execute this Power of Attorney as of this 12th day of August, 
     1994.



                                             /s/ Mark E. Strome
                                             ------------------------------
                                             Mark E. Strome

<PAGE>
 
                                                                        11 of 12
                                   Exhibit B

              JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(f) (1)
              ----------------------------------------------------

This agreement is made pursuant to Rule 13d-1(f)(1) under the Securities
Exchange Act of 1934, as amended (the "Act") by and among the parties listed
below, each referred to herein as a "Joint Filer."  The Joint Filers agree that
a statement of beneficial ownership as required by Section 13(d) of the Act and
the Rules thereunder may be filed on each of their behalf on Schedule 13D or
Schedule 13G, as appropriate, and that said joint filing may thereafter be
amended by further joint filings.  The Joint Filers states that they each
satisfy the requirements for making a joint filing under Rule 13d-1.

Dated: February 2, 1998


/s/ Jeffrey S. Lambert
- ---------------------------------
Mark E. Strome

STROME SUSSKIND INVESTMENT MANAGEMENT, L.P.
By SSCO, Inc., its General Partner

By: /s/ Jeffrey S. Lambert
   -------------------------------------------
   Jeffrey S. Lambert, Chief Financial Officer

SSCO, INC.

By: /s/ Jeffrey S. Lambert
   -------------------------------------------
   Jeffrey S. Lambert, Chief Financial Officer

<PAGE>
 
                                                                   Page 12 of 12

 
                                   Exhibit C

             Identification and Classification of Subsidiary Which
       Acquired Security Being Reported On By the Parent Holding Company


SSIM, a registered investment adviser, acquired "beneficial ownership" of the
securities being reported on as a result of its discretionary authority to
acquire, dispose and (with respect to certain of such securities) vote the
securities being reported on.  Under a series of SEC no-action letters,
including the letter issued to Warren Buffet and Berkshire Hathaway, Inc.
(available December 18, 1987), SSCO and Strome are each considered the
equivalent of a parent holding company of SSIM and are therefore eligible to
report their indirect beneficial ownership in such shares on Schedule 13G.


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