HOLLIS EDEN PHARMACEUTICALS INC /DE/
SC 13G, 2000-02-10
PHARMACEUTICAL PREPARATIONS
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                                 UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549


                                 SCHEDULE 13G
                                (Rule 13d-102)

           INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
          TO RULES 13d-11(b)(c), AND (d) AND AMENDMENTS THERETO FILED
                           PURSUANT TO RULE 13d-2(b)
                             (Amendment No. 1)/1/


                       HOLLIS-EDEN PHARMACEUTICALS, INC.
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                         Common Stock, par value $.01
- --------------------------------------------------------------------------------
                        (Title of Class of Securities)

                                  435902 10 1
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

                                   12/31/99
- --------------------------------------------------------------------------------
            (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     [_] Rule 13d-1(b)

     [_] Rule 13d-1(c)

     [X] Rule 13d-1(d)

______________________

1.   The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.

     The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).

                               Page 1 of 4 pages
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- ------------------------                                ------------------------
  CUSIP No. 435902 10 1              13G                    Page 2 of 4 Pages
- ------------------------                                ------------------------


- ------------------------------------------------------------------------------
      NAMES OF REPORTING PERSONS
 1    I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

      RICHARD B. HOLLIS

- ------------------------------------------------------------------------------
      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP          (a) [_]
 2
                                                                (b) [_]

- ------------------------------------------------------------------------------
      SEC USE ONLY
 3


- ------------------------------------------------------------------------------
      CITIZENSHIP OR PLACE OF ORGANIZATION
 4
      UNITED STATES

- ------------------------------------------------------------------------------
                          SOLE VOTING POWER
                     5
     NUMBER OF            3,513,258 (1)

      SHARES       -----------------------------------------------------------
                          SHARED VOTING POWER
   BENEFICIALLY      6
                          0
     OWNED BY
                   -----------------------------------------------------------
       EACH               SOLE DISPOSITIVE POWER
                     7
    REPORTING             3,513,258 (1)

      PERSON       -----------------------------------------------------------
                          SHARED DISPOSITIVE POWER
       WITH          8
                          0
- ------------------------------------------------------------------------------
      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 9
      3,513,258 (1)

- ------------------------------------------------------------------------------
      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
10
                                                                    [_]

- ------------------------------------------------------------------------------
      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
11
      29.6%

- ------------------------------------------------------------------------------
      TYPE OF REPORTING PERSON
12
      IN

- ------------------------------------------------------------------------------

(1)   INCLUDES 396,667 SHARES ISSUABLE UPON EXERCISE OF OPTIONS TO PURCHASE
COMMON STOCK AND 393,250 SHARES ISSUABLE UPON EXERCISE OF WARRANTS TO PURCHASE
393,250 SHARES OF COMMON STOCK WITHIN 60 DAYS OF DECEMBER 31, 1999.

                               Page 2 of 4 pages

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Item 1(a).   Name of Issuer:

             Hollis-Eden Pharmaceuticals, Inc.
             ---------------------------------

Item 1(b).   Address of Issuer's Principal Executive Offices:

             9333 Genesee Avenue, Suite 200
             ------------------------------

             San Diego, CA 92121
             -------------------

Item 2(a).   Name of Person Filing:

             Richard B. Hollis
             -----------------

Item 2(b).   Address of Principal Business Office or, if none, Residence:

             9333 Genesee Avenue, Suite 200
             ------------------------------

             San Diego, CA 92121
             -------------------

Item 2(c).   Citizenship:

             United States
             -------------

Item 2(d).   Title of Class of Securities:

             Common Stock, par value $.01
             ----------------------------

Item 2(e).   CUSIP Number:

             435902 10 1
             -----------

Item 3.      Not applicable.

Item 4.      Ownership.

             (a)  Amount beneficially owned:

                  3,513,258 shares, including 396,667 shares issuable upon
                  --------------------------------------------------------
                  exercise of options and 393,250 shares issuable upon exercise
                  -------------------------------------------------------------
                  of warrants outstanding within 60 days of 12/31/99.
                  ---------------------------------------------------

             (b)  Percent of Class:  29.6%

             (c)  Number of shares as to which such person has:

                  (i)   sole power to vote or to direct the vote:  3,513,258
                  (ii)  shared power to vote or to direct the vote:  0
                  (iii) sole power to dispose or to direct the disposition of:
                        3,513,258
                  (iv)  shared power to dispose or to direct the disposition of:
                        0

                               Page 3 of 4 pages

<PAGE>

Item 5.  Ownership of Five Percent or Less of a Class.

         If this statement is being filed to report the fact that as of the date
         hereof the reporting person has ceased to be the beneficial owner of
         more than five percent of the class of securities, check the following:
         [_]

Item 6.  Ownership of More than Five Percent on Behalf of Another Person.

         Not applicable.

Item 7.  Identification and Classification of the Subsidiary Which Acquired the
         Security Being Reported on by the Parent Holding Company.

         Not applicable.

Item 8.  Identification and Classification of Members of the Group.

         Not applicable.

Item 9.  Notice of Dissolution of Group

         Not applicable.

Item 10. Certification

         Not applicable.


                                   SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.


                                              February 7, 2000
                                              ----------------------------------
                                              Date

                                              /s/ Richard B. Hollis
                                              ----------------------------------
                                              Signature

                                              Richard B. Hollis
                                              ----------------------------------
                                              Name/Title

                               Page 4 of 4 pages


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