LXR BIOTECHNOLOGY INC
SC 13D/A, 1999-11-22
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE> 1

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

SCHEDULE 13D/A

UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 4)
LXR Biotechnology Inc.
- -----------------------------------------
(Name of Issuer)
Common Stock
- -----------------------------------------
(Title of Class Securities)
502468101
- -----------------------------------------
(CUSIP Number)
David J. Allen, Esquire, 290 South County Farm Rd., Third
Floor, Wheaton, IL 60187-4526 (630) 588-7200
- -----------------------------------------
(Name, Address and Telephone Number of Person Authorized to
Receive Notice and Communications)
November 19, 1999
- -----------------------------------------
(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on
Schedule 13G to report the acquisition which is the subject
of this Schedule 13D, and is filing this schedule because of
Section 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the
following box / /.

Note: Schedules filed in paper format shall include a
signed original and five copies of the schedule,
including all exhibits.  See Section 240.13d-7 for other
parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect
to the subject class of securities, and for any subsequent
amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page
shall not be deemed to be "filed" for the purpose of Section
18 of the Securities Exchange Act of 1934 ("Act") or
otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act
(however, see the Notes).

<PAGE> 2

SCHEDULE 13D/A

CUSIP NO. 502468101      PAGE  2  OF  4  PAGES

1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Grace Brothers, Ltd.

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(See
Instructions)
(a)/ /
(b)/ /

3 SEC USE ONLY

4 SOURCE OF FUNDS(See Instructions)
WC

5 CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e)/  /

6 CITIZENSHIP OR PLACE OR ORGANIZATION
ILLINOIS LIMITED PARTNERSHIP
              7 SOLE VOTING POWER
NUMBER OF       0 SHARES
SHARES
BENEFICIALLY  8 SHARED VOTING POWER
OWNED BY
EACH
REPORTING     9 SOLE DISPOSITIVE POWER
PERSON          0 SHARES
WITH         10 SHARED DISPOSITIVE POWER

11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
PERSON
0 SHARES

12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
CERTAIN SHARES(See Instructions)/  /

13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
0%

14 TYPE OF REPORTING PERSON*
BD,PN

<PAGE 3>

Page  3  of  4  Pages

Item 1.  Security and Issuer

This statement relates to the common stock, par value $.01
per share (the "Common Stock"), issued by LXR Biotechnology
Inc., a Delaware corporation (the "Company"), whose principal
executive offices are located at 1401 Marina Way South,
Richmond, California 94804.

Item 4.  Purpose of Transaction

On November 19, 1999, Grace Brothers, Ltd. ("Grace") sold
all shares owned by it, as shown on Schedule A.

Grace does not have any present plans or proposals which
would result in any of the actions enumerated in clauses (a)
- - (j) of Item 4 of Schedule 13D/A under the Act.

Item 5.  Interest in Securities of the Issuer.

(a) As of the date of this filing, Grace owns no shares of
Common Stock.

(b) Not applicable.

(c) The transactions effected by the Filers during the past
60 days are set forth on Schedule A hereto.

(d) Not applicable.

(e) Not applicable.

<PAGE 4>

Page   4   of  4  Pages

Item 6.  Contracts, Arrangements, Understandings or
Relationships with Respect to Securities of the Issuer.

There are no contracts, arrangements, understandings or other
relationships with respect to any securities of the Company.

Item 7.  Items to be filed as Exhibits.

Schedule A - Trade Activity for LXR Biotechnology Common
Stock

SIGNATURE

Grace Brothers, Ltd., after reasonable inquiry and to the
best of its knowledge and belief, certifies that the
information set forth in this statement is true, complete and
correct.

Dated:  November 22, 1999

Grace Brothers, Ltd.

By:/s/ Bradford T. Whitmore
   ------------------------
       Bradford T. Whitmore
       General Partner

SCHEDULE A

TRADE ACTIVITY FOR LXR BIOTECHNOLOGY COMMON STOCK.  SOLD IN A
PRIVATELY NEGOTIATED TRANSACTION.
<TABLE>
<CAPTION>
DATE      AMOUNT      PRICE/SHARE
<S>       <C>         <C>
11/19/99  9,191,034   $.02
</TABLE>



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