HUMAN GENOME SCIENCES INC
10-Q, 1996-05-13
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>
================================================================================

                                    FORM 10-Q


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

   For quarterly period ended March 31, 1996     Commission File Number 0-22962

                           HUMAN GENOME SCIENCES, INC.
                           (Exact name of registrant)
        Delaware                                          22-3178468
 (State of organization)                         (I.R.S. Employer Identification
                                                            Number)

              9410 Key West Avenue, Rockville, Maryland 20850-3331
              (Address of principal executive offices and zip code)

                                 (301) 309-8504
                         (Registrant's telephone Number)




         Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days.

Yes    X          No
      ----             -----


The number of shares of the registrant's  common stock  outstanding on April 30,
1996 was 18,650,355.




================================================================================
<PAGE>

                                              TABLE OF CONTENTS
<TABLE>
<CAPTION>


                                                                                                     Page
                                                                                                    Number
                                                                                                    ------
<S>                                                                                                  <C>
PART I.       FINANCIAL INFORMATION

Item 1.       Financial Statements

              Statements of Operations for the three months
                  ended March 31, 1996 and 1995..............................................         3

              Balance Sheets at March 31, 1996 and December 31, 1995.........................         4

              Statements of Cash Flows for the three months
                  ended March 31, 1996 and 1995..............................................         5

              Notes to Financial Statements..................................................         6

Item 2.       Management's Discussion and Analysis of
                  Financial Condition and Results of Operations..............................         7


PART II.       OTHER INFORMATION

Item 6.       Exhibits and Reports on Form 8-K...............................................         8

              Signatures.....................................................................         8

              Exhibit Index..................................................................    Exhibit Volume

</TABLE>

                                                         2
<PAGE>

                          PART I. FINANCIAL INFORMATION
                           HUMAN GENOME SCIENCES, INC.
                            STATEMENTS OF OPERATIONS


                                                        Three months ended
                                                               March 31,
                                                         1996            1995
                                                   ---------------  ------------
                                                   (dollars in thousands, except
                                                         per share amounts)
                                                                
Revenue - research and development
     collaborative contracts........................ $    13,934   $     - 0 -

Costs and expenses:
     Research and development:
         Direct expenditures........................       6,491         4,838
         Payments under research services agreement.       2,521         2,389
                                                     -----------  ------------
Total research and development......................       9,012         7,227

General and administrative..........................       2,023         1,718
                                                     -----------  ------------

         Total costs and expenses...................      11,035         8,945
                                                     -----------  ------------

Income (loss) from operations.......................       2,899       (8,945)

Interest income.....................................       1,586         1,081

Interest expense....................................       (108)         (137)
                                                     -----------  ------------

Income (loss) before taxes..........................       4,377       (8,001)

Provision (benefit) for income taxes................          90       (2,001)
                                                     -----------  ------------

NET INCOME (LOSS)................................... $     4,287  $    (6,000)
                                                     ===========  ============

NET INCOME (LOSS) PER SHARE......................... $      0.22  $     (0.40)
                                                     ===========  ============

Weighted average shares outstanding.................  19,489,122    14,858,784
                                                     ============ ============



                See accompanying notes to financial statements.

                                        3
<PAGE>

<TABLE>
<CAPTION>
                                            HUMAN GENOME SCIENCES, INC.
                                                  BALANCE SHEETS


                                                       ASSETS
                                                       ------
                                                                                   March 31,         December 31,
                                                                                ---------------   ------------------
                                                                                     1996                1995
                                                                                ---------------   ------------------
                                                                                       (dollars in thousands)

<S>                                                                             <C>               <C>               
Current assets:
     Cash and cash equivalents .................................................$        31,275   $           39,853
     Short-term investments.....................................................         95,558               65,609
     Prepaid expenses and other current assets..................................          2,825                2,163
                                                                                ---------------   ------------------
         Total current assets...................................................        129,658              107,625
Furniture and equipment (net of accumulated depreciation).......................         17,401               16,005
Restricted investments..........................................................          1,699                2,000
Other assets....................................................................          1,327                1,333
                                                                                ---------------   ------------------
         TOTAL..................................................................$       150,085   $          126,963
                                                                                ===============   ==================

                                                    LIABILITIES
                                                    -----------

Current liabilities:
     Current portion of long-term debt..........................................$           444   $              444
     Accounts payable and accrued expenses......................................          1,599                2,341
     Accrued payroll and related taxes..........................................          1,100                  692
     Current obligation under capital leases....................................          1,208                1,174
     Deferred income............................................................          3,000                2,000
     Income taxes payable.......................................................             90                - 0 -
                                                                                ---------------   ------------------
         Total current liabilities..............................................          7,441                6,651
Long-term debt, net of current portion..........................................          3,112                3,112
Obligations under capital leases, net of current portion........................            874                1,220
Other liabilities...............................................................            367                  374
                                                                                ---------------   ------------------
         TOTAL..................................................................         11,794               11,357

                                                STOCKHOLDERS' EQUITY
                                                --------------------

Common stock....................................................................            186                  182
Additional paid-in capital......................................................        161,019              142,624
Unearned portion of compensatory stock and warrants.............................           (715)                (885)
Unrealized gain (loss) on investments available for sale........................           (124)                  47
Retained earnings (deficit).....................................................        (22,075)             (26,362)
                                                                                ---------------   ------------------
         Total stockholders' equity.............................................        138,291              115,606
                                                                                ---------------   ------------------
         TOTAL..................................................................$       150,085   $          126,963
                                                                                ===============   ==================
</TABLE>

                See accompanying notes to financial statements.



                                        4
<PAGE>
                                            HUMAN GENOME SCIENCES, INC.
                                             STATEMENTS OF CASH FLOWS

<TABLE>
<CAPTION>


                                                                                            Three months ended
                                                                                                 March 31,
                                                                                           1996            1995
                                                                                      --------------  --------------
                                                                                            (dollars in thousands)

<S>                                                                                 <C>             <C>           
Cash flows from operating activities:
    Net income (loss)...............................................................$        4,287  $      (6,000)
    Adjustments to reconcile net income (loss) to net cash provided by
        (used in) operating activities:
        Accrued interest on U.S. Treasury bills and commercial paper................          (333)          (241)
        Depreciation................................................................         1,322            964
        Loss due to disposal and write-down of furniture and equipment..............         - 0 -              6
        Issuance of and accretion of compensatory stock and warrants................           170            176
        Changes in operating assets and liabilities:
           Prepaid expenses and other current assets................................          (691)          (301)
           Funds available - facility fund..........................................         - 0 -            (35)
           Other assets.............................................................             6            (45)
           Accounts payable and accrued expenses....................................          (498)          (210)
           Accrued payroll and related taxes........................................           408            140
           Deferred income..........................................................         1,000          4,500
           Income taxes payable.....................................................            90         (2,134)
           Other liabilities........................................................            (7)           (10)
                                                                                    --------------  --------------
        Net cash provided by (used in) operating activities.........................         5,754         (3,190)
                                                                                    --------------  --------------

Cash flows from investing activities:
    Capital expenditures - furniture and equipment..................................        (2,963)        (2,668)
    Purchase of short-term investments and marketable securities....................       (62,890)       (15,216)
    Proceeds from sales and maturities of short-term investments....................        33,133         12,818

                                                                                    --------------  --------------
        Net cash used in investing activities.......................................       (32,720)        (5,066)
                                                                                    --------------  --------------
Cash flows from financing activities:
    Proceeds of long-term debt......................................................         - 0 -          1,090
    Collateral on line of credit - restricted.......................................          301              (5)
    Payments on capital lease obligations...........................................         (312)           (212)
    Proceeds from issuance of common stock (net of expenses)........................       18,399             135
                                                                                    --------------  --------------
        Net cash provided by financing activities...................................       18,388           1,008
                                                                                    --------------  --------------
NET DECREASE IN CASH AND CASH EQUIVALENTS...........................................       (8,578)         (7,248)

Cash and cash equivalents - beginning of period.....................................       39,853          36,027
                                                                                    --------------  --------------
CASH AND CASH EQUIVALENTS - END OF PERIOD...........................................$      31,275  $       28,779
                                                                                    ==============  ==============

Supplemental  disclosures of cash flow information:  
     Cash paid during the period for:
        Interest....................................................................$          50  $           50
        Income taxes................................................................        - 0 -             508
</TABLE>

                See accompanying notes to financial statements.

                                                         5
<PAGE>


                         NOTES TO FINANCIAL STATEMENTS


Note 1.  Interim Financial Statements


The  accompanying  financial  statements  of Human Genome  Sciences,  Inc. ( the
"Company") have not been audited by independent auditors, except for the balance
sheet at December  31, 1995.  In the opinion of the  Company's  management,  the
financial  statements  reflect all  adjustments  necessary to present fairly the
results of operations for the three month periods ended March 31, 1996 and 1995,
the Company's  financial  position at March 31, 1996, and the cash flows for the
three month periods ended March 31, 1996 and 1995.  These  adjustments  are of a
normal recurring nature.

Certain  notes and other  information  have been  condensed  or omitted from the
interim  financial  statements  presented in this Quarterly report on Form 10-Q.
Therefore  these  financial  statements  should be read in conjunction  with the
Company's 1995 Annual Report on Form 10-K.

The results of  operations  for the three month  period ended March 31, 1996 are
not necessarily indicative of future financial results.

Note 2.  Income Taxes

The Company  produced income before taxes of $4,377,000  during the three months
ended March 31, 1996.  As of December 31,  1995,  the Company had net  operating
loss  carryforwards for federal income tax purposes of approximately $22 million
and available tax credit  carryforwards  of $4,347,000  that expire  between the
years  2000  and  2010.  The  Company  estimates  that  the net  operating  loss
carryforwards and tax credit carryforwards will be sufficient to offset ordinary
taxable  income,  if any,  during  1996,  and thus has provided for income taxes
during the current period based upon the  Alternative  Minimum Tax provisions of
the Internal Revenue Code.


                                        6
<PAGE>


                     MANAGEMENT'S DISCUSSION AND ANALYSIS OF
                  FINANCIAL CONDITION AND RESULTS OF OPERATION

               Three Month Periods ended March 31, 1996 and 1995.

Results of Operations
- - ---------------------

Quarters Ended March 31, 1996 and March 31, 1995
- - ------------------------------------------------

    Revenues.  The Company had  revenues of $13.9  million for the three  months
ended March 31, 1996  compared with no revenues for the three months ended March
31, 1995.  Revenue  consisted of $6.9 million upon the  achievement of Milestone
III pursuant to the Collaboration  Agreement with SmithKline  Beecham ("SB") and
$7.0  million  in license  fees and  milestone  payments  from  Pioneer  Hi-Bred
International,  Inc. (Pioneer") and F. Hoffmann-La Roche ("Roche").  The Company
expects  that its revenue  sources for at least the next  several  years will be
limited to interest  income,  payments under existing  Collaboration  Agreements
which are  contingent  on meeting  certain  product  milestones,  license  fees,
proceeds from the sale of rights and other payments from other collaborators and
licensees under existing or future arrangements,  to the extent that the Company
enters into any such further arrangements.

    Expenses.  Research and development expenses increased from $7.2 million for
the three  months  ended March 31, 1995 to $9.0 for the three months ended March
31, 1996. The Company's  payments to The Institute for Genomic Research ("TIGR")
were $2.5 million for the quarter  ended March 31, 1996 compared to $2.4 million
for the quarter ended March 31, 1995.  The  Company's  direct  expenditures  for
research and development  increased from $4.8 million for the three months ended
March 31, 1995 to $6.5 million for the three months ended March 31, 1996.  These
increases resulted  primarily from significant  expansions in the Company's cell
biology,  protein  expression  and  pharmacology  departments  and  reflect  the
Company's  increasing  emphasis  on  determinng  the  biological  functions  and
possible medical  utilities of genes and proteins  discovered as a result of the
Company's gene discovery efforts.

    General and  administrative  expenses  increased  from $1.7  million for the
three  months  ended March 31, 1995 to $2.0  million for the three  months ended
March 31, 1996. The increase resulted primarily from significantly  higher legal
expenses associated with filing a larger number of patent applications  relating
to  genes  and  proteins   discovered  by  the  Company.   Interest  income  was
significantly  higher for the three months ended March 31, 1996  compared to the
three months ended March 31, 1995 due to higher cash balances.

    Net Income.  The Company  recorded net income of $4.3  million,  or $.22 per
share for the three  months  ended  March 31,  1996  compared  to a loss of $6.0
million,  or $.40 per share for the  three  months  ended  March 31,  1995.  The
difference  in results  for the three  months  ended  March 31, 1996 and 1995 is
primarily due to the receipt of $13.9 million in license and milestone  revenues
during the three  months ended March 31, 1996,  which was  partially  off-set by
higher expenses.

Liquidity and Capital Resources
- - -------------------------------

    The Company had working capital of $122.2 million at March 31, 1996 compared
to $101.0  million at December 31,  1995.  The  increase  resulted  from the net
income  generated  during the quarter,  and the sale of 339,065 shares of Common
Stock to SB upon completion of the third milestone  ("Milestone  III") under the
Company's  collaboration  agreement  with  SB  for  $18.1  million,  which  were
partially off-set by capital expenditures and payments on capitalized leases.

    The Company's funds are currently  invested in U.S.  Treasury and government
agency  obligations,  investment-grade  commercial  paper  and  interest-bearing
securities having a maximum maturity of two years.

    The Company is committed to pay TIGR approximately  $50.5 million during the
next seven years, including  approximately $18.4 million through March 31, 1998.
At March 31, 1996, the Company had outstanding  commitments for construction and
equipment purchases totaling approximately $500,000.

    The  Company  expects  that  its  existing  funds,   interest  income,   and
anticipated  payments  from  Pioneer  and Roche upon  successful  completion  of
various  milestones  will be  sufficient to fund the  Company's  operations  for
approximately  three  years.  The  Company  may  require  additional  sources of
financing  or funds  prior to the time that it will  receive any  revenues  from
product sales or royalties on product sales by licensees.  The Company's  future
capital requirements and

                                        7
<PAGE>

the  adequacy  of its  available  funds will depend on many  factors,  including
scientific progress in its research and development  programs,  the magnitude of
those  programs,  the  ability of the  Company to  establish  collaborative  and
licensing  arrangements,  the cost involved in preparing,  filing,  prosecuting,
maintaining and enforcing patent claims and competing  technological  and market
developments.


                           PART II. OTHER INFORMATION


Item 6.  Exhibits and Reports on Form 8-K

         (a) Exhibits

          11.1) Computation of per share date.


          (b) Reports on Form 8-K

          None.


                                   SIGNATURES
                                   ----------


         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                  HUMAN GENOME SCIENCES, INC.



                                  BY: /s/William A. Haseltine
                                      --------------------------------
                                      William A. Haseltine, Ph.D.
                                      Chairman and Chief Executive Officer




                                  BY: /s/Melvin D. Booth
                                      ---------------------------------
                                      Melvin D. Booth
                                      President and Chief Operating Officer and
                                            Acting Chief Financial Officer




Dated:  May 13, 1996


                                        8
<PAGE>

                                  EXHIBIT INDEX



                                                                          Page
Exhibit                                                                  Number
- - -------                                                                  ------

  11.1     Computation of per share data................................








                                        9
<PAGE>


                                                                    EXHIBIT 11.1

                          COMPUTATION OF PER SHARE DATA
                      (In thousands except per share data)


<TABLE>
<CAPTION>

                                                                                    Three months ended,
                                                                                         March 31,
                                                                               ------------------------------
                                                                                    1996            1995
                                                                               --------------  --------------

<S>                                                                            <C>             <C>            
Net Income (Loss)............................................................. $        4,287  $       (6,000)
                                                                               ==============  ==============

Primary:
    Weighted average number of common shares outstanding......................         18,438          14,859

    Shares issuable upon exercise of dilutive stock options and warrants --- net
        of shares assumed to be repurchased (at the average market price for the
        period) from exercise proceeds........................................          1,051           - 0 -
                                                                               --------------  --------------
Shares used for computation...................................................         19,489          14,859
                                                                               ==============  ==============

Earnings (loss) per share of common stock (primary)........................... $         0.22  $       (0.40)
                                                                               ==============  ==============

Assuming full dilution:
    Weighted average number of common shares outstanding......................         18,438          14,859

    Shares issuable upon exercise of dilutive stock options and warrants --- net
        of shares assumed to be repurchased (at the higher of period-end  market
        price or the average market price for the period) from exercise proceeds        1,051           - 0 -
                                                                               --------------  --------------
Shares used for computation...................................................         19,489          14,859
                                                                               ==============  ==============

Earnings (loss) per share of common stock (assuming full
    dilution)  (1)............................................................ $         0.22  $       (0.40)
                                                                               ==============  ==============

Notes & assumptions:
(1)  Not presented as dilution is less than 3%.
</TABLE>


<PAGE>

<TABLE> <S> <C>


<ARTICLE>                     5
<MULTIPLIER>                  1000
       
<S>                                          <C>
<PERIOD-TYPE>                                    3-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-END>                               MAR-31-1996
<CASH>                                          31,275
<SECURITIES>                                    95,558
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                               129,658
<PP&E>                                          26,190
<DEPRECIATION>                                   8,789
<TOTAL-ASSETS>                                 150,085
<CURRENT-LIABILITIES>                            7,441
<BONDS>                                          3,986
<COMMON>                                           186
                                0
                                          0
<OTHER-SE>                                     138,108
<TOTAL-LIABILITY-AND-EQUITY>                   150,085
<SALES>                                              0
<TOTAL-REVENUES>                                13,934
<CGS>                                                0
<TOTAL-COSTS>                                        0
<OTHER-EXPENSES>                                 9,012
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                 108
<INCOME-PRETAX>                                  4,377
<INCOME-TAX>                                        90
<INCOME-CONTINUING>                              4,287
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                     4,287
<EPS-PRIMARY>                                      .22
<EPS-DILUTED>                                      .22
        
<PAGE>
</TABLE>


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