HUMAN GENOME SCIENCES INC
S-8, EX-23.2, 2000-09-21
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                  EXHIBIT 23.2


               CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS


         We  consent  to the  incorporation  by  reference  in the  Registration
Statement on Form S-8,  pertaining to the Principia  Pharmaceutical  Corporation
1999 Equity  Compensation  Plan,  of our report  dated  February  9, 2000,  with
respect to the financial statements of Human Genome Sciences,  Inc., included in
its Annual Report on Form 10-K for the year ended December 31, 1999,  filed with
the Securities and Exchange Commission.


                                     /s/ Ernst & Young LLP

McLean, Virginia
September 20, 2000



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