SIGMA ALDRICH CORP
SC 13G/A, 1999-02-03
CHEMICALS & ALLIED PRODUCTS
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 14)*


                            SIGMA-ALDRICH CORPORATION
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                   826552 10 1
              -----------------------------------------------------
                                 (CUSIP Number)



                                December 31, 1998
             ------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)


Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

                      |_|     Rule 13d-1(b)

                      |_|     Rule 13d-1(c)

                      |X|     Rule 13d-1(d)

*

*        The  remainder  of this cover page shall be filled out for a  reporting
         person's  initial filing on this form with respect to the subject class
         of securities,  and for any subsequent amendment containing information
         which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                        (Continued on following page(s))
                               Page 1 of 4 Pages

<PAGE>



CUSIP No. 826552  10  1                                             2 of 4 Pages




  1       NAME OF REPORTING PERSON
          S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
          Alfred R. Bader (###-##-####)

  2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a)   [ ]

          Not Applicable                                              (b)   [ ]

  3       SEC USE ONLY

  4       CITIZENSHIP OR PLACE OF ORGANIZATION

          United States


        NUMBER OF            5       SOLE VOTING POWER
                                     5,274,260

         SHARES


       BENEFICIALLY          6       SHARED VOTING POWER
                                     0

        OWNED BY


          EACH               7       SOLE DISPOSITIVE POWER
                                     5,274,260

       REPORTING


         PERSON              8       SHARED DISPOSITIVE POWER
                                     0

          WITH


  9      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         5,274,260

 10      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES[ ]
         N/A

 11      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
         5.2%

 12      TYPE OF REPORTING PERSON*
         IN


                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
                      INCLUDE BOTH SIDES OF THE COVER PAGE,
                 RESPONSES TO ITEMS 1-7 (INCLUDING EXHIBITS) OF
                  THE SCHEDULE, AND THE SIGNATURE ATTESTATION.




<PAGE>






CUSIP No. 826552  10  1                                        Page 3 of 4 Pages


          This  amendment  no. 14 to Schedule  13G with regard to  Sigma-Aldrich
Corporation  is being filed on behalf of the  undersigned to amend Item 4 of the
originally  filed Schedule 13G.  Except as expressly  stated herein,  there have
been no material  changes in the information set forth in the Schedule 13G. 

 Item 4.  Ownership:  

          (a) Amount  Beneficially  Owned:
              5,274,260  

          (b) Percent of Class: 
              5.2% 

          (c) Number of shares as to which such person has:

              (i)   sole power to vote or to direct the vote:   5,274,260 Shares

              (ii)  shared power to vote or to direct the vote: 0 Shares

              (iii) sole power to dispose or to direct the disposition of:
                    5,274,260 Shares

              (iv)  shared power to dispose or to direct the disposition of:
                    0 Shares


<PAGE>

CUSIP No. 826552 10  1                                         Page 4 of 4 Pages


                                    SIGNATURE


          After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.



          February 1, 1999
          Date


       /s/Alfred R. Bader
          Alfred R. Bader



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