SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
________________________
SCHEDULE 13G
Information Statement pursuant to Rule 13d-1 and 13d-2
(Final Amendment)
GelTex Pharmaceuticals, Inc.
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(Name of Issuer)
Common Stock, $.01 par value
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(Title of Class of Securities)
368538104
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(CUSIP Number)
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CUSIP No. 368538104 Page 2 of 4 Pages
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1) Name of Reporting Person Domain Partners II,
S.S. or I.R.S. Identification L.P.
No. of Above Person
_________________________________________________________________
2) Check the Appropriate Box (a) [ ]
if a Member of a Group (b) [ ]
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3) SEC Use Only
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4) Citizenship or Place Delaware
of Organization
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Number of 5) Sole Voting -0-
Shares Beneficially Power
Owned by Each
Reporting Person
________________________________________
6) Shared Voting
Power -0-
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7) Sole Disposi- -0-
tive Power
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8) Shared Dis-
positive Power -0-
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9) Aggregate Amount Beneficially -0-
Owned by Each Reporting person
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10) Check if the Aggregate
Amount in Row (9)
Excludes Certain Shares
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11) Percent of Class
Represented by -0-
Amount in Row (9)
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12) Type of Reporting
Person PN
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CUSIP No. 368538104 Page 3 of 4 Pages
Final Amendment to Schedule 13G
_______________________________
Reference is hereby made to the statement on Schedule 13G
originally filed with the Securities and Exchange Commission on February 8,
1996 (the "Schedule 13G"). Terms defined in the Schedule 13G are used
herein as so defined.
The Schedule 13G is hereby amended as follows:
Item 4 - Ownership.
(a) Amount Beneficially Owned:
0 shares of Common Stock
(b) Percent of Class:
0%
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote: -0-
(ii) shared power to vote or to direct the vote: -0-
(iii) sole power to dispose or to direct the disposition
of: -0-
(iv) shared power to dispose or to direct the
disposition of: -0-
Item 5 - Ownership of Five Percent or Less of a Class:
This statement is being filed to report that as of the date
hereof Domain II has ceased to be the beneficial owner of more than five
percent of the Common Stock.
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CUSIP No. 368538104 Page 4 of 4 Pages
Signature:
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.
DOMAIN PARTNERS II, L.P.
By: One Palmer Square Associates,
II, L.P., General Partner
By /s/ Kathleen K. Schoemaker
_________________________________
Attorney-in-Fact
Date: February 2, 1998
