ELLIOTT ASSOCIATES LP
SC 13D/A, 2000-02-22
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D
                    Under the Securities Exchange Act of 1934

INFORMATION  TO BE INCLUDED IN  STATEMENTS  FILED  PURSUANT TO RULE 13d-1(a) AND
AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a)

                               (Amendment No. 4)*

Vion Pharmaceuticals, Inc.
(Name of Issuer)

Common Stock, $.01 par value
(Title of Class of Securities)

927624106
(CUSIP Number)

Martin D. Sklar, Esq., Kleinberg,  Kaplan, Wolff & Cohen, P.C. 551 Fifth Avenue,
New York, New York 10176 Tel: (212) 986-6000 (Name, Address and Telephone Number
of Person Authorized to Receive Notices and Communications)

February 22, 2000
(Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box
[ ].

Note:  Schedules  filed in paper format shall include a signed original and five
copies of the  schedule,  including  all  exhibits.  See Rule 13d-7(b) for other
parties to whom copies are to be sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                       (Continued on the following pages)
                                  (Page 1 of 7)


<PAGE>





1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Elliott Associates, L.P.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  WC

5.   CHECK BOX IF DISCLOSURE OF LEGAL  PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS
     2(d) or 2(e) [ ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  1,483,394

8        SHARED VOTING POWER
                  0

9.       SOLE DISPOSITIVE POWER
                  1,483,394

10.      SHARED DISPOSITIVE POWER
                  0

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                  1,483,394

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*   [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  7.5%

14.      TYPE OF REPORTING PERSON*
                  PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Westgate International, L.P.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  WC

5.       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
         REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)     [ ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Cayman Islands, British West Indies

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  0

8.       SHARED VOTING POWER
                  1,485,819

9.       SOLE DISPOSITIVE POWER
                  0

10.      SHARED DISPOSITIVE POWER
                  1,485,819

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
         REPORTING PERSON
                  1,485,819

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*           [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  7.5%

14.      TYPE OF REPORTING PERSON*
                  PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Martley International, Inc.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  00

5.   CHECK BOX IF DISCLOSURE OF LEGAL  PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS
     2(d) or 2(e)           [ ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH
REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  0

8.       SHARED VOTING POWER
                  1,485,819

9.       SOLE DISPOSITIVE POWER
                  0

10.      SHARED DISPOSITIVE POWER
                  1,485,819

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
         REPORTING PERSON
                  1,485,819

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*           [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  7.5%

14.      TYPE OF REPORTING PERSON*
                  CO

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


         This  statement is filed  pursuant to Rule 13d-2(a) with respect to the
shares  of  common  stock,   $.01  par  value  (the  "Common   Stock")  of  Vion
Pharmaceuticals, Inc. (the "Issuer") beneficially owned by the Reporting Persons
specified herein as of February 22, 2000 and amends and supplements the Schedule
13D dated August 14, 1998,  as amended on September 3, 1998,  April 15, 1999 and
October 28, 1999 (the "Schedule 13D").  Except as set forth herein, the Schedule
13D, as previously amended, is unmodified.

ITEM 3.  Source and Amount of Funds or Other Consideration

         The source and amount of funds used by Elliott in making its  purchases
of the shares of Common Stock beneficially owned by it are set forth below:

SOURCE OF FUNDS                                      AMOUNT OF FUNDS
Working Capital                                      $4,994,510

         The source and amount of funds used by Westgate in making its purchases
of the shares of Common Stock beneficially owned by it are set forth below:

SOURCE OF FUNDS                                      AMOUNT OF FUNDS
Working Capital                                      $4,468,037

ITEM 5.  Interest in Securities of the Issuer

         (a)  Elliott  beneficially  owns  1,483,394  shares  of  Common  Stock,
consisting  of  1,327,130  shares of Common Stock held  outright,  78,132 of the
Issuer's Class A Warrants  ("Class A Warrants")  which are  exercisable  for (i)
78,132 shares of Common Stock, and (ii) 78,132 of the Issuer's Class B Warrants,
which are in turn  exercisable  for  78,132  shares of Common  Stock.  Elliott's
beneficial ownership of 1,483,394 shares of Common Stock constitutes 7.5% of the
total outstanding shares of Common Stock.

         Elliott's  2,500 shares of the Issuer's 5% Convertible  Preferred Stock
Series 1998 ("5%  Preferred  Stock") were  automatically  converted into 753,512
shares of Common  Stock on  February  22,  2000  pursuant  to  Section 12 of the
Certificate of Designations of the 5% Preferred Stock.

         Westgate and Martley  together  beneficially  own  1,485,819  shares of
Common  Stock,  consisting  of 1,330,371  shares of Common Stock held  outright,
77,724 Class A Warrants  which are  exercisable  for (i) 77,724 shares of Common
Stock,  and (ii)  77,724 of the  Issuer's  Class B  Warrants,  which are in turn
exercisable  for  77,724  shares  of  Common  Stock.  Westgate's  and  Martley's
aggregate  beneficial  ownership of 1,485,819 shares of Common Stock constitutes
7.5% of the total outstanding shares of Common Stock.
         Westgate's  2,500  shares  of 5%  Preferred  Stock  were  automatically
converted  into 753,512  shares of Common Stock on February 22, 2000 pursuant to
Section 12 of the Certificate of Designations of the 5% Preferred Stock.

         The Issuer has  exercised  its option to call all  outstanding  Class A
Warrants for $.05 per  underlying  Share of Common Stock  effective on March 13,
2000.

         Together,  Elliott,  Westgate and Martley  beneficially  own  2,969,213
shares of Common Stock  constituting  14.8% of the outstanding  shares of Common
Stock.

         (b) Elliott has the power to vote or direct the vote of, and to dispose
or direct the disposition of, the shares of Common Stock  beneficially  owned by
it.

         Westgate  and Martley  have the shared power to vote or direct the vote
of,  and to dispose or direct  the  disposition  of, the shares of Common  Stock
owned by Westgate and Martley.

         (c) The following transactions were effected by Elliott during the past
sixty (60) days:

                                                      Approx. Price per
                                Amount of Shs.         Share (excl. of
Date             Security       Bought (Sold)            commissions)

2/15/00          Common           (11,600)               $16.0533
2/16/00          Common           (16,500)               $15.5392
2/17/00          Common           (20,000)               $15.5154
2/18/00          Common            (2,250)               $14.5444
2/22/00          Common            (1,500)               $15.0000

         The above transactions were effected by Elliott over-the-counter.

         The following  transactions  were effected by Westgate  during the past
sixty (60) days:

                                                       Approx. Price per
                                  Amount of Shs.        Share (excl. of
Date             Security         Bought (Sold)           commissions)

2/15/00          Common           (11,600)                $16.0533
2/16/00          Common           (16,500)                $15.5392
2/17/00          Common           (20,000)                $15.5154
2/18/00          Common            (2,250)                $14.5444
2/22/00          Common            (1,500)                $15.0000

         The above transactions were effected by Westgate over-the-counter.

         No  other  transactions  with  respect  to the  Common  Stock  that are
required to be reported  and have not been  previously  reported on Schedule 13D
were effected by either Elliott or Westgate during the past sixty (60) days.

         (d) No person  other than Elliott has the right to receive or the power
to direct the receipt of dividends  from,  or the proceeds from the sale of, the
shares of Common Stock beneficially owned by Elliott.

         No person  other than  Westgate and Martley has the right to receive or
the power to direct the receipt of dividends from, or the proceeds from the sale
of, the shares of Common Stock beneficially owned by Westgate and Martley.

         (e)      Not applicable.

                                   SIGNATURES

         After  reasonable  inquiry and to the best of its knowledge and belief,
the undersigned each certifies that the information with respect to it set forth
in this statement is true, complete and correct.

Dated: February 22, 2000

                                       ELLIOTT ASSOCIATES, L.P.
                                       By:  Braxton Associates, L.P., as General
                                                    Partner

                                       By: Braxton Associates, Inc., as General
                                                    Partner


                                         By: /s/ Elliot Greenberg
                                                 Elliot Greenberg
                                                 Vice President

                                        WESTGATE INTERNATIONAL, L.P.
                                        By: Martley International, Inc.,
                                             as Attorney-in-Fact


                                          By: /s/ Elliot Greenberg
                                                  Elliot Greenberg
                                                  Vice President

                                       MARTLEY INTERNATIONAL, INC.


                                          By: /s/ Elliot Greenberg
                                                  Elliot Greenberg
                                                  Vice President



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