JANUS ASPEN SERIES, 485APOS, 1999-11-01

JANUS ASPEN SERIES
485APOS, 1999-11-01

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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form N-1A

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 [X]

Pre- Effective Amendment No. [ ]

Post-Effective Amendment No. 21 [X]

and/or

REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT
OF 1940 [X]

Amendment No. 23 [X]

(Check appropriate box or boxes.)

JANUS ASPEN SERIES
(Exact Name of Registrant as Specified in Charter)

100 Fillmore Street, Denver, Colorado 80206-4928
Address of Principal Executive Offices (Zip Code)

Registrant's Telephone No., including Area Code: 303-333-3863

Thomas A. Early - 100 Fillmore Street, Denver, Colorado 80206-4928
(Name and Address of Agent for Service)

Approximate Date of Proposed Offering: January 15, 2000

It is proposed that this filing will become effective (check appropriate box):
[ ] immediately upon filing pursuant to paragraph (b) of Rule 485
[ ] on (date) pursuant to paragraph (b) of Rule 485
[ ] 60 days after filing pursuant to paragraph (a)(1) of Rule 485
[ ] on (date) pursuant to paragraph (a)(1) of Rule 485
[X] 75 days after filing pursuant to paragraph (a)(2) of Rule 485 (on
January 15, 2000).
[ ] on (date) pursuant to paragraph (a)(2) of Rule 485.

If appropriate, check the following box:
[ ] This post-effective amendment designates a new effective date for a
previously filed post-effective amendment.

<PAGE>

JANUS ASPEN SERIES

Cross Reference Sheet
Between the Prospectuses and Statements of
Additional Information and Form N-1A Item

This Post-Effective Amendment No. 21 contains the Janus Aspen Series Global Life
Sciences Portfolio and Global Technology Portfolio - Institutional Shares and
Service Shares Prospectuses and Statements of Additional Information. The Cross
Reference Sheet for Other Series of Janus Aspen Series are included in a
previous post-effective amendment relating to those series.

FORM N-1A ITEM CAPTION IN PROSPECTUSES

PART A

1. Front and Back Cover Pages Cover Pages

2. Risk/Return Summary: Risk/Return Summary
Investments, Risks, and
Performance

3. Risk/Return Summary: Fee Risk/Return Summary
Table

4. Investment Objectives, Investment Objectives, Principal
Principal Investment Investment Strategies, and Risks;
Strategies, and Related Risks Rating Categories

5. Management's Discussion of Not Applicable
Fund Performance

6. Management, Organization, and Management of the Funds
Capital Structure

7. Shareholder Information Shareholder's Guide; Other
Information; Distributions and Taxes

8. Distribution Arrangements Distributions and Taxes

9. Financial Highlights Financial Highlights
Information

<PAGE>

FORM N-1A ITEM CAPTION IN STATEMENTS OF
ADDITIONAL INFORMATION

PART B

10. Cover Page and Table of Cover Page; Table of Contents
Contents

11. Fund History Miscellaneous Information

12. Description of the Fund and Classification, Portfolio Turnover,
Its Investments and Risks Investment Policies and Restrictions,
Investment Strategies and Risks;

13. Management of the Fund Investment Adviser; Trustees and
Officers

14. Control Persons and Principal Principal Shareholders
Holders of Securities

15. Investment Advisory and Other Investment Adviser; Custodian,
Services Transfer Agent, and Certain
Affiliations; Portfolio Transactions
and Brokerage; Trustees and Officers;
Miscellaneous Information

16. Brokerage Allocation and Portfolio Transactions and
Other Practices Brokerage

17. Capital Stock and Other Purchases; Redemptions; Miscellaneous
Securities Information

18. Purchase, Redemption, and Purchases; Redemptions; Miscellaneous
Pricing of Shares Information

19. Taxation of the Fund Income Dividends, Capital Gains
Distributions and Tax Status

20. Underwriters Custodian, Transfer Agent, and
Certain Affiliations

<PAGE>

21. Calculation of Performance Performance Information
Data

22. Financial Statements Not Applicable

<PAGE>

THE INFORMATION IN THIS PROSPECTUS IS NOT COMPLETE AND MAY BE CHANGED. WE MAY
NOT SELL THESE SECURITIES UNTIL THE REGISTRATION STATEMENT FILED WITH THE
SECURITIES AND EXCHANGE COMMISSION IS EFFECTIVE. THIS PROSPECTUS IS NOT AN OFFER
TO SELL THESE SECURITIES AND IS NOT SOLICITING AN OFFER TO BUY THESE SECURITIES
IN ANY STATE WHERE THE OFFER IS NOT PERMITTED.

[JANUS LOGO]

Subject to Completion

Preliminary Prospectus Dated November 1, 1999

Janus Aspen Series

PROSPECTUS

JANUARY 15, 2000

Global Life Sciences Portfolio

Global Technology Portfolio

THE SECURITIES AND EXCHANGE COMMISSION HAS NOT APPROVED OR
DISAPPROVED OF THESE SECURITIES OR PASSED ON THE ACCURACY OR
ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE
CONTRARY IS A CRIMINAL OFFENSE.
<PAGE>

[JANUS LOGO]

This prospectus describes two mutual funds (the "Portfolios")
which are series of Janus Aspen Series. Both of these Portfolios
offer two classes of shares. The Institutional Shares (the
"Shares") are sold under the name of "Janus Aspen Series" and
are offered by this prospectus in connection with investment in
and payments under variable annuity contracts and variable life
insurance contracts, as well as certain qualified retirement
plans.

Janus Aspen Series sells and redeems its Shares at net asset
value without sales charges, commissions or redemption fees.
Each variable insurance contract involves fees and expenses that
are not described in this Prospectus. Certain Portfolios may not
be available in connection with a particular contract and
certain contracts may limit allocations among the Portfolios.
See the accompanying contract prospectus for information
regarding contract fees and expenses and any restrictions on
purchases or allocations.

This prospectus contains information that a prospective
purchaser of a variable insurance contract or plan participant
should consider in conjunction with the accompanying separate
account prospectus of the specific insurance company product
before allocating purchase payments or premiums to the
Portfolios.
<PAGE>
Table of contents

<TABLE>
<S> <C>
RISK/RETURN SUMMARY
Global Life Sciences Portfolio........................... 2
Global Technology Portfolio.............................. 2
Fees and expenses........................................ 4
INVESTMENT OBJECTIVES, PRINCIPAL INVESTMENT STRATEGIES AND
RISKS
General portfolio policies............................... 7
Risks for Global Life Sciences Portfolio and Global
Technology Portfolio..................................... 9
Risks Common to both Portfolios..........................
Investment techniques....................................
MANAGEMENT OF THE PORTFOLIOS
Investment adviser....................................... 12
Management expenses and expense limits................... 12
Investment personnel..................................... 13
OTHER INFORMATION........................................... 14
DISTRIBUTIONS AND TAXES
Distributions............................................ 15
Taxes.................................................... 15
SHAREHOLDER'S GUIDE
Purchases................................................ 16
Redemptions.............................................. 16
Shareholder communications............................... 17
FINANCIAL HIGHLIGHTS........................................ 18
GLOSSARY
Glossary of investment terms............................. 19

</TABLE>

Table of contents 1
<PAGE>
Risk return summary

The Global Life Sciences and Global Technology Portfolios are designed
for long-term investors who seek growth of capital and who can
tolerate the greater risks associated with common stock investments.

1. WHAT ARE THE INVESTMENT OBJECTIVES OF THE GLOBAL LIFE SCIENCES AND GLOBAL
TECHNOLOGY PORTFOLIOS?

- --------------------------------------------------------------------------------

Global Life Sciences and Global Technology Portfolios seek long-term
growth of capital.

The Portfolios' Trustees may change these objectives without a
shareholder vote and the Portfolios will notify you of any changes
that are material. If there is a material change to a Portfolio's
objective or policies, you should consider whether that Portfolio
remains an appropriate investment for you. There is no guarantee that
a Portfolio will meet its objective.

2. WHAT ARE THE MAIN INVESTMENT STRATEGIES OF THE PORTFOLIOS?

The portfolio managers apply a "bottom up" approach in choosing
investments. In other words, they look for companies with earnings
growth potential one at a time. If a portfolio manager is unable to
find investments with earnings growth potential, a significant portion
of a Portfolio's assets may be in cash or similar investments.

GLOBAL LIFE SCIENCES PORTFOLIO invests primarily in equity securities
of U.S. and foreign companies selected for their growth potential.
Normally, it invests at least 65% of its total assets in securities of
companies that the portfolio manager believes have a life science
orientation. As a fundamental policy, the Portfolio normally invests
at least 25% of its total assets, in the aggregate, in the following
industry groups: health care; pharmaceuticals; agriculture;
cosmetics/personal care; and biotechnology.

GLOBAL TECHNOLOGY PORTFOLIO invests primarily in equity securities of
U.S. and foreign companies selected for their growth potential. Under
normal circumstances, it invests at least 65% of its total assets in
securities of companies that the portfolio manager believes will
benefit significantly from advances or improvements in technology.

3. WHAT ARE THE MAIN RISKS OF INVESTING IN THE PORTFOLIOS?

The biggest risk is that the Portfolios' returns may vary, and you
could lose money. If you are considering investing in either of the
Portfolios, remember that they are each designed for long-term
investors who can accept the risks of investing in a portfolio with
significant common stock holdings. Common stocks tend to be more
volatile than other investment choices.

The value of a Portfolio may decrease if the value of an individual
company in the portfolio decreases. The value of a Portfolio could
also decrease if the stock market goes down. If the value of a
Portfolio decreases, its net asset value (NAV) will also decrease,
which means if you sell your shares in a Portfolio you would get back
less money.

Global Life Sciences Portfolio and Global Technology Portfolio may
have significant exposure to foreign markets. As a result, their
returns and NAV may be affected to a large degree by fluctuations in
currency exchange rates or political or economic conditions in a
particular country.

Global Life Sciences Portfolio and Global Technology Portfolio are
nondiversified. In other words, they may hold larger positions in a
smaller number of securities than a diversified fund. As a result, a
single security's increase or decrease in value may have a greater
impact on a Portfolio's NAV and total return.

An investment in these Portfolios is not a bank deposit and is not
insured or guaranteed by the Federal Deposit Insurance Corporation or
any other government agency.

2 Janus Aspen Series
<PAGE>

GLOBAL LIFE SCIENCES PORTFOLIO concentrates its investments in related
industry groups. Because of this, companies in its portfolio may share
common characteristics and react similarly to market developments. For
example, many companies with a life science orientation are highly
regulated and may be dependent upon certain types of technology. As a
result, changes in government funding or subsidies, new or anticipated
legislative changes, or technological advances could affect the value
of such companies and, therefore, the Portfolio's NAV. The Portfolio's
returns may be more volatile than those of a less concentrated
portfolio.

Although GLOBAL TECHNOLOGY PORTFOLIO does not concentrate its
investments in specific industries, it may invest in companies related
in such a way that they react similarly to certain market pressures.
For example, competition among technology companies may result in
increasingly aggressive pricing of their products and services, which
may affect the profitability of companies in the portfolio. In
addition, because of the rapid pace of technological development,
products or services developed by companies in the Portfolio's
portfolio may become rapidly obsolete or have relatively short product
cycles. As a result, the Portfolio's returns may be considerably more
volatile than the returns of a fund that does not invest in similarly
related companies.

Risk return summary 3
<PAGE>

FEES AND EXPENSES

SHAREHOLDER FEES, such as sales loads, redemption fees or exchange
fees, are charged directly to an investor's account. All Janus funds
are no-load investments, so you will not pay any shareholder fees when
you buy or sell shares of the Portfolios. However, each variable
insurance contract involves fees and expenses not described in this
prospectus. See the accompanying contract prospectus for information
regarding contract fees and expenses and any restrictions on purchases
or allocations.

ANNUAL FUND OPERATING EXPENSES are paid out of a Portfolio's assets
and include fees for portfolio management, maintenance of shareholder
accounts, shareholder servicing, accounting and other services. You do
not pay these fees directly but, as the example on the next page
shows, these costs are borne indirectly by all shareholders.

This table and example are designed to assist participants in
qualified plans that invest in the Shares of the Portfolios in
understanding the fees and expenses that you may pay as an investor in
the Shares. This table describes the fees and expenses that you may
pay if you buy and hold Shares of the Portfolios. The information
shown is based upon estimated annualized expenses the Portfolios'
shares expect to incur during their initial fiscal year. OWNERS OF
VARIABLE INSURANCE CONTRACTS THAT INVEST IN THE SHARES SHOULD REFER TO
THE VARIABLE INSURANCE CONTRACT PROSPECTUS FOR A DESCRIPTION OF FEES
AND EXPENSES, AS THE TABLE AND EXAMPLE DO NOT REFLECT DEDUCTIONS AT
THE SEPARATE ACCOUNT LEVEL OR CONTRACT LEVEL FOR ANY CHARGES THAT MAY
BE INCURRED UNDER A CONTRACT.

Total Annual Fund Total Annual Fund
Operating Expenses Operating Expenses
Management Other Without Waivers Total With Waivers
Fee Expenses or Reductions* Waivers and Reductions or Reductions*
<S> <C> <C> <C> <C> <C>
Global Life Sciences Portfolio 0.75% 0.30% 1.05% N/A 1.05%
Global Technology Portfolio 0.75% 0.30% 1.05% 0.02% 1.03%
</TABLE>

- --------------------------------------------------------------------------------

* All expenses are based on the estimated annualized expenses the shares
expect to incur during their fiscal year and are stated both with and
without contractual waivers and fee reductions by Janus Capital. Fee
reductions for Global Life Sciences and Global Technology Portfolios
reduce the Management Fee to the level of the corresponding Janus retail
fund. Other waivers, if applicable, are first applied against the
Management Fee and then against "Other Expenses." Janus Capital has
agreed to continue the waivers and fee reductions until at least the
next annual renewal of the advisory agreement.

- --------------------------------------------------------------------------------

EXAMPLE:
THE FOLLOWING EXAMPLE IS BASED ON EXPENSES WITHOUT WAIVERS OR
REDUCTIONS. This example is intended to help you compare the cost of
investing in the Portfolios with the cost of investing in other mutual
funds. The example assumes that you invest $10,000 in each of the
Portfolios for the time periods indicated then redeem all of your shares
at the end of those periods. The example also assumes that your
investment has a 5% return each year, and that the Portfolios' operating
expenses remain the same. Although your actual costs may be higher or
lower, based on these assumptions your costs would be:

<TABLE>
<CAPTION>
1 Year 3 Years
------------------
<S> <C> <C>
Global Life Sciences Portfolio $107 $ 334
Global Technology Portfolio $105 $ 326
</TABLE>

4 Janus Aspen Series
<PAGE>
Investment objectives, principal investment
strategies and risks

Each of the Portfolios has a similar investment objective and similar
principal investment strategies to a Janus retail fund:

<TABLE>
<S> <C>
Global Life Sciences Portfolio Janus Global Life Sciences Fund
Global Technology Portfolio Janus Global Technology Fund
</TABLE>

Although it is anticipated that each Portfolio and its corresponding
retail fund will hold similar securities, differences in asset size,
cash flow needs and other factors may result in differences in
investment performance. The expenses of each Portfolio and its
corresponding retail fund are expected to differ. The variable
contract owner will also bear various insurance related costs at the
insurance company level. You should review the accompanying separate
account prospectus for a summary of fees and expenses.

This section takes a closer look at the investment objectives of the
Global Life Sciences and Global Technology Portfolios, their principal
investment strategies and certain risks of investing in the
Portfolios. Strategies and policies that are noted as "fundamental"
cannot be changed without a shareholder vote.

Please carefully review the "Risks" section of this Prospectus on
pages 9-11 for a discussion of risks associated with certain
investment techniques. We've also included a Glossary with
descriptions of investment terms used throughout this Prospectus.

INVESTMENT OBJECTIVES AND PRINCIPAL INVESTMENT STRATEGIES

GLOBAL LIFE SCIENCES PORTFOLIO

Global Life Sciences Portfolio seeks long-term growth of capital. It
pursues its objective by investing primarily in equity securities of
U.S. and foreign companies selected for their growth potential.
Normally, it invests at least 65% of its total assets in securities of
companies that the portfolio manager believes have a life science
orientation. As a fundamental policy, the Portfolio normally invests
at least 25% of its total assets, in the aggregate, in the following
industry groups: health care; pharmaceuticals; agriculture;
cosmetics/personal care; and biotechnology.

GLOBAL TECHNOLOGY PORTFOLIO

Global Technology Portfolio seeks long-term growth of capital. It
pursues its objective by investing primarily in equity securities of
U.S. and foreign companies selected for their growth potential.
Normally, it invests at least 65% of its total assets in securities of
companies that the portfolio manager believes will benefit
significantly from advances or improvements in technology. These
companies generally fall into two categories:

a. Companies that the portfolio manager believes have or will develop
products, processes or services that will provide significant
technological advancements or improvements; and

b. Companies that the portfolio manager believes rely extensively on
technology in connection with their operations or services.

Investment objectives, principal investment strategies and risks 5
<PAGE>

The following questions and answers are designed to help you better understand
the Portfolios' principal investment strategies.

1. HOW ARE COMMON STOCKS SELECTED?

Each of the Portfolios may invest substantially all of its assets in
common stocks if its portfolio manager believes that common stocks
will appreciate in value. The portfolio managers generally take a
"bottom up" approach to selecting companies. In other words, they seek
to identify individual companies with earnings growth potential that
may not be recognized by the market at large. They make this
assessment by looking at companies one at a time, regardless of size,
country of organization, place of principal business activity, or
other similar selection criteria. Realization of income is not a
significant consideration when choosing investments for the
Portfolios. Income realized on the Portfolios' investments will be
incidental to their objectives.

2. ARE THE SAME CRITERIA USED TO SELECT FOREIGN SECURITIES?

Generally, yes. The portfolio managers seek companies that meet their
selection criteria, regardless of where a company is located. Foreign
securities are generally selected on a stock-by-stock basis without
regard to any defined allocation among countries or geographic
regions. However, certain factors such as expected levels of
inflation, government policies influencing business conditions, the
outlook for currency relationships, and prospects for economic growth
among countries, regions or geographic areas may warrant greater
consideration in selecting foreign securities. There are no
limitations on the countries in which the Portfolios may invest and
the Portfolios may at times have significant foreign exposure.

3. WHAT DOES "LIFE SCIENCE ORIENTATION" MEAN IN RELATION TO GLOBAL LIFE SCIENCES
PORTFOLIO?

Generally speaking, the "life sciences" relate to maintaining or
improving quality of life. So, for example, companies with a "life
science orientation" include companies engaged in research,
development, production or distribution of products or services
related to health and personal care, medicine or pharmaceuticals. Life
science oriented companies also include companies that the portfolio
manager believes have growth potential primarily as a result of
particular products, technology, patents or other market advantages in
the life sciences. Life sciences encompass a variety of industries,
including health care, nutrition, agriculture, medical diagnostics,
nuclear and biochemical research and development and health care
facilities ownership and operation.

4. HOW DOES GLOBAL TECHNOLOGY PORTFOLIO'S INDUSTRY POLICY DIFFER FROM THAT OF
GLOBAL LIFE SCIENCES PORTFOLIO?

Unlike Global Life Sciences Portfolio, Global Technology Portfolio
will not concentrate its investments in any particular industry or
group of related industries. As a result, its portfolio manager may
have more flexibility to find companies that he believes will benefit
from advances or improvements in technology in a number of industries.
Nevertheless, the Portfolio may hold a significant portion of its
assets in industries such as: aerospace/defense; biotechnology;
computers; office/business equipment; semi-conductors; software;
telecommunications; and telecommunications equipment.

6 Janus Aspen Series
<PAGE>

GENERAL PORTFOLIO POLICIES OF THE PORTFOLIOS

Each of the following policies applies to both of the Portfolios. The
percentage limitations included in these policies and elsewhere in
this Prospectus apply at the time of purchase of the security. So, for
example, if a Portfolio exceeds a limit as a result of market
fluctuations or the sale of other securities, it will not be required
to dispose of any securities.

CASH POSITION
When a portfolio manager believes that market conditions are
unfavorable for profitable investing, or when he or she is otherwise
unable to locate attractive investment opportunities, the Portfolios'
cash or similar investments may increase. In other words, the
Portfolios do not always stay fully invested in stocks and bonds. Cash
or similar investments generally are a residual - they represent the
assets that remain after a portfolio manager has committed available
assets to desirable investment opportunities. However, a portfolio
manager may also temporarily increase a Portfolio's cash position to
protect its assets or maintain liquidity. Partly because the portfolio
managers act independently of each other, the cash positions of the
Portfolios may vary significantly.

When a Portfolio's investments in cash or similar investments
increase, it may not participate in market advances or declines to the
same extent that it would if the Portfolio remained more fully
invested in stocks.

OTHER TYPES OF INVESTMENTS

The Global Life Sciences and Global Technology Portfolios invest
primarily in domestic and foreign equity securities, which may include
preferred stocks, common stocks, warrants and securities convertible
into common or preferred stocks. The Portfolios may also invest to a
lesser degree in other types of securities. These securities (which
are described in the Glossary) may include:

- debt securities

- indexed/structured securities

- high-yield/high-risk securities (less than 35% of each Portfolio's
assets)

- options, futures, forwards and other types of derivatives for
hedging purposes or for non-hedging purposes such as seeking to
enhance return

- securities purchased on a when-issued, delayed delivery or forward
commitment basis

ILLIQUID INVESTMENTS

Each Portfolio may invest up to 15% of its net assets in illiquid
investments. An illiquid investment is a security or other position
that cannot be disposed of quickly in the normal course of business.
For example, some securities are not registered under U.S. securities
laws and cannot be sold to the U.S. public because of SEC regulations
(these are known as "restricted securities"). Under procedures adopted
by the Portfolios' Trustees, certain restricted securities may be
deemed liquid, and will not be counted toward this 15% limit.

FOREIGN SECURITIES
The Portfolios may invest without limit in foreign equity and debt
securities. The Portfolios may invest directly in foreign securities
denominated in a foreign currency and not publicly traded in the
United

Investment objectives, principal investment strategies and risks 7
<PAGE>

States. Other ways of investing in foreign securities include
depositary receipts or shares, and passive foreign investment
companies.

SPECIAL SITUATIONS
Each Portfolio may invest in special situations. A special situation
arises when, in the opinion of a Portfolio's manager, the securities
of a particular issuer will be recognized and appreciate in value due
to a specific development with respect to that issuer. Developments
creating a special situation might include, among others, a new
product or process, a technological breakthrough, a management change
or other extraordinary corporate event, or differences in market
supply of and demand for the security. A Portfolio's performance could
suffer if the anticipated development in a "special situation"
investment does not occur or does not attract the expected attention.

PORTFOLIO TURNOVER
The Portfolios generally intend to purchase securities for long-term
investment although, to a limited extent, a Portfolio may purchase
securities in anticipation of relatively short-term price gains.
Short-term transactions may also result from liquidity needs,
securities having reached a price or yield objective, changes in
interest rates or the credit standing of an issuer, or by reason of
economic or other developments not foreseen at the time of the
investment decision. A Portfolio may also sell one security and
simultaneously purchase the same or a comparable security to take
advantage of short-term differentials in bond yields or securities
prices. Changes are made in a Portfolio's holdings whenever its
portfolio manager believes such changes are desirable. Portfolio
turnover rates are generally not a factor in making buy and sell
decisions.

Global Technology Portfolio may invest in companies with relatively
short product cycles, for example, 6 to 9 months. Consequently its
portfolio turnover may be more frequent. Increased portfolio turnover
may result in higher costs for brokerage commissions, dealer mark-ups
and other transaction costs and may also result in taxable capital
gains. Higher costs associated with increased portfolio turnover may
offset gains in a Portfolio's performance.

8 Janus Aspen Series
<PAGE>

RISKS FOR GLOBAL LIFE SCIENCES AND GLOBAL TECHNOLOGY PORTFOLIOS

Because the Portfolios may invest substantially all of their assets in
common stocks, the main risk is the risk that the value of the stocks
they hold might decrease in response to the activities of an
individual company or in response to general market and/or economic
conditions. If this occurs, a Portfolio's share price may also
decrease. A Portfolio's performance may also be affected by risks
specific to certain types of investments, such as foreign securities,
derivative investments, non-investment grade debt securities or
companies with relatively small market capitalizations.

The following questions and answers are designed to help you better understand
some of the risks of investing in the Portfolios.

1. THE FUNDS MAY INVEST IN SMALLER OR NEWER COMPANIES. DOES THIS CREATE ANY
SPECIAL RISKS?

Particularly in the area of technology, many attractive investment
opportunities may be smaller, start-up companies offering emerging
products or services. Smaller or newer companies may suffer more
significant losses as well as realize more substantial growth than
larger or more established issuers because they may lack depth of
management, be unable to generate funds necessary for growth or
potential development, or be developing or marketing new products or
services for which markets are not yet established and may never
become established. In addition, such companies may be insignificant
factors in their industries and may become subject to intense
competition from larger or more established companies. Securities of
smaller or newer companies may have more limited trading markets than
the markets for securities of larger or more established issuers, and
may be subject to wide price fluctuations. Investments in such
companies tend to be more volatile and somewhat more speculative.

2. HOW COULD THE PORTFOLIOS' INVESTMENTS IN FOREIGN SECURITIES AFFECT THEIR
PERFORMANCE?

The Portfolios may invest without limit in foreign securities either
indirectly (e.g., depositary receipts) or directly in foreign markets.
Investments in foreign securities, including those of foreign
governments, may involve greater risks than investing in domestic
securities because the Portfolios' performance may depend on issues
other than the performance of a particular company. These issues
include:

- CURRENCY RISK. As long as a Portfolio holds a foreign security, its
value will be affected by the value of the local currency relative
to the U.S. dollar. When a Portfolio sells a foreign denominated
security, its value may be worth less in U.S. dollars even if the
security increases in value in its home country. U.S. dollar
denominated securities of foreign issuers may also be affected by
currency risk.

- POLITICAL AND ECONOMIC RISK. Foreign investments may be subject to
heightened political and economic risks, particularly in emerging
markets which may have relatively unstable governments, immature
economic structures, national policies restricting investments by
foreigners, different legal systems, and economies based on only a
few industries. In some countries, there is the risk that the
government may take over the assets or operations of a company or
that the government may impose taxes or limits on the removal of a
Portfolio's assets from that country.

- REGULATORY RISK. There may be less government supervision of foreign
markets. As a result, foreign issuers may not be subject to the
uniform accounting, auditing and financial reporting standards and
practices applicable to domestic issuers and there may be less
publicly available information about foreign issuers.

- MARKET RISK. Foreign securities markets, particularly those of
emerging market countries, may be less liquid and more volatile than
domestic markets. Certain markets may require payment for securities

Investment objectives, principal investment strategies and risks 9
<PAGE>

before delivery and delays may be encountered in settling securities
transactions. In some foreign markets, there may not be protection
against failure by other parties to complete transactions.

- TRANSACTION COSTS. Costs of buying, selling and holding foreign
securities, including brokerage, tax and custody costs, may be
higher than those involved in domestic transactions.

3. WHAT IS "INDUSTRY RISK"?

Industry risk is the possibility that a group of related stocks will
decline in price due to industry-specific developments. Companies in
the same or similar industries may share common characteristics and
are more likely to react similarly to industry-specific market or
economic developments. In the life sciences, for example, many
companies are subject to government regulation and approval of their
products and services, which may affect their price or availability.
In addition, the products and services offered by these companies may
quickly become obsolete in the face of scientific or technological
developments. The economic outlook of such companies may fluctuate
dramatically due to changes in regulatory or competitive environments.
In technology-related industries, competitive pressures may have a
significant effect on the performance of companies in which Global
Technology Portfolio may invest. In addition, technology and
technology-related companies often progress at an accelerated rate,
and these companies may be subject to short product cycles and
aggressive pricing which may increase their volatility.

Global Life Sciences Portfolio invests in a concentrated portfolio,
which may result in greater exposure to related industries. As a
result, the Portfolio may be more volatile than a less concentrated
portfolio. Although Global Technology Portfolio does not "concentrate"
in a specific group of industries, it may, at times, have significant
exposure to companies in a variety of technology-related industries.

4. HOW DOES THE NONDIVERSIFIED STATUS OF THE PORTFOLIOS AFFECT THEIR RISK?

Diversification is a way to reduce risk by investing in a broad range
of stocks or other securities. A "nondiversified" portfolio has the
ability to take larger positions in a smaller number of issuers.
Because the appreciation or depreciation of a single stock may have a
greater impact on the NAV of a nondiversified portfolio, its share
price can be expected to fluctuate more than a comparable diversified
portfolio. This fluctuation, if significant, may affect the
performance of a Portfolio.

5. ARE THERE SPECIAL RISKS ASSOCIATED WITH INVESTMENTS IN HIGH-YIELD/HIGH-RISK
SECURITIES?

High-yield/high-risk securities (or "junk" bonds) are securities rated
below investment grade by the primary rating agencies such as Standard
& Poor's and Moody's. The value of lower quality securities generally
is more dependent on credit risk, or the ability of the issuer to meet
interest and principal payments, than investment grade debt
securities. Issuers of high-yield securities may not be as strong
financially as those issuing bonds with higher credit ratings and are
more vulnerable to real or perceived economic changes, political
changes or adverse developments specific to the issuer.

6. HOW DO THE PORTFOLIOS TRY TO REDUCE RISK?

The Portfolios may use futures, options and other derivative
instruments to "hedge" or protect their portfolios from adverse
movements in securities prices and interest rates. The Portfolios may
also use a variety of currency hedging techniques, including forward
currency contracts, to manage exchange rate risk. The portfolio
managers believe the use of these instruments will benefit the
Portfolios. However, a Portfolio's performance could be worse than if
the Portfolio had not used such instruments if a portfolio manager's
judgement proves incorrect. Risks associated with the use of
derivative instruments are described in the SAI.

10 Janus Aspen Series
<PAGE>

7. I'VE HEARD A LOT ABOUT HOW THE CHANGE TO THE YEAR 2000 COULD AFFECT COMPUTER
SYSTEMS. DOES THIS CREATE ANY SPECIAL RISKS?

The portfolio managers carefully research each potential investment
before making an investment decision and, among other things, consider
Year 2000 readiness when selecting portfolio holdings. However, there
is no guarantee that the information a portfolio manager receives
regarding a company's Year 2000 readiness is completely accurate. If a
company has not satisfactorily addressed Year 2000 issues, the
Portfolio's performance could suffer.

Investment objectives, principal investment strategies and risks 11
<PAGE>
Management of the portfolios

INVESTMENT ADVISER

Janus Capital, 100 Fillmore Street, Denver, Colorado 80206-4928, is
the investment adviser to each of the Portfolios and is responsible
for the day-to-day management of the investment portfolios and other
business affairs of the Portfolios.

Janus Capital began serving as investment adviser to Janus Fund in
1970 and currently serves as investment adviser to all of the Janus
retail funds, acts as sub-adviser for a number of private-label mutual
funds and provides separate account advisory services for
institutional accounts.

Janus Capital furnishes continuous advice and recommendations
concerning each Portfolio's investments. Janus Capital also furnishes
certain administrative, compliance and accounting services for the
Portfolios, and may be reimbursed by the Portfolios for its costs in
providing those services. In addition, Janus Capital employees serve
as officers of the Trust and Janus Capital provides office space for
the Portfolios and pays the salaries, fees and expenses of all
Portfolio officers and those Trustees who are affiliated with Janus
Capital.

Participating insurance companies that purchase the Portfolios' shares
may perform certain administrative services relating to the Portfolios
and Janus Capital or the Portfolios may pay those companies for such
services.

MANAGEMENT EXPENSES AND EXPENSE LIMITS

Each Portfolio pays Janus Capital a management fee which is calculated
daily. The advisory agreement with each Portfolio spells out the
management fee and other expenses that the Portfolios must pay. Each
of the Portfolios is subject to the following management fee schedule
(expressed as an annual rate). In addition, the Shares of each
Portfolio incur expenses not assumed by Janus Capital, including
transfer agent and custodian fees and expenses, legal and auditing
fees, printing and mailing costs of sending reports and other
information to existing shareholders, and independent Trustees' fees
and expenses.

<TABLE>
<CAPTION>
Average Daily
Net Assets Annual Rate Expense Limit
Fee Schedule of Portfolio Percentage (%) Percentage (%)
- -----------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C>
Global Life Sciences Portfolio First $300 Million 0.75 1.25(1)(2)
Global Technology Portfolio Next $200 Million 0.70
Over $500 Million 0.65
- ------------------------------------------------------------------------------------------------------------------
</TABLE>

(1) Janus Capital has agreed to reduce Global Life Sciences and Global
Technology Portfolios' management fee to the extent that such fee exceeds
the effective rate of the Janus retail fund corresponding to such Portfolio.
Janus Capital has agreed to continue such waivers until at least the next
annual renewal of the advisory contracts. The effective rate is the
management fee calculated by the corresponding retail fund as of the last
day of each calendar quarter (expressed as an annual rate). The effective
rates of Janus Global Life Sciences Fund and Janus Global Technology Fund
were % and %, respectively, for the quarter ended December 31, 1999.

(2) Janus Capital has agreed to limit the Portfolios' expenses as indicated
until at least the next annual renewal of the advisory contracts.

12 Janus Aspen Series
<PAGE>

INVESTMENT PERSONNEL

PORTFOLIO MANAGERS

C. MIKE LU

- --------------------------------------------------------------------------------

is Executive Vice President and portfolio manager of Global
Technology Portfolio and Janus Global Technology Fund, which he
has managed since inception. He joined Janus Capital in 1991 as a
research analyst and has consistently focused on companies in the
technology industry. Mr. Lu has a Bachelor of Arts in History and
a Bachelor of Arts in Economics from Yale University. Mr. Lu
received the Chartered Financial Analyst designation.

THOMAS R. MALLEY

- --------------------------------------------------------------------------------

is Executive Vice President and portfolio manager of Global Life
Sciences Portfolio and Janus Global Life Sciences Fund, which he
has managed since inception. He joined Janus Capital in 1991 as a
research analyst and has focused on companies in the health care,
pharmaceutical and biotechnology industries. Mr. Malley has a
Bachelor of Science in Biology from Stanford University and
received the Chartered Financial Analyst designation.

Management of the portfolios 13
<PAGE>
Other information

CLASSES OF SHARES

Each Portfolio currently offers two classes of Shares, one of which,
the Institutional Shares, are offered pursuant to this prospectus and
are sold under the name Janus Aspen Series. The Shares offered by this
Prospectus are available only in connection with investment in and
payments under variable insurance contracts as well as certain
qualified retirement plans. Service Shares of each Portfolio are
offered by separate prospectus and are available only in connection
with variable insurance contracts and certain qualified retirement
plans offered by entities that require payment for distribution and
shareholder servicing. Because the expenses of each class may differ,
the performance of each class is expected to differ. If you would like
additional information about the Service Shares, please call
1-800-525-0020.

CONFLICTS OF INTEREST

The Trust's shares are available only to variable annuity and variable
life separate accounts of insurance companies that are unaffiliated
with Janus Capital and to certain qualified retirement plans. Although
the Portfolios do not currently anticipate any disadvantages to policy
owners because each Portfolio offers its shares to such entities,
there is a possibility that a material conflict may arise. The
Trustees monitor events in order to identify any disadvantages or
material irreconcilable conflicts and to determine what action, if
any, should be taken in response. If a material disadvantage or
conflict occurs, the Trustees may require one or more insurance
company separate accounts or qualified plans to withdraw its
investments in one or more Portfolios or substitute shares of another
Portfolio. If this occurs, a Portfolio may be forced to sell its
securities at disadvantageous prices. In addition, the Trustees may
refuse to sell shares of any Portfolio to any separate account or
qualified plan or may suspend or terminate the offering of a
Portfolio's shares if such action is required by law or regulatory
authority or is in the best interests of that Portfolio's
shareholders. It is possible that a qualified plan investing in the
Portfolios could lose its qualified plan status under the Internal
Revenue Code, which could have adverse tax consequences on insurance
company separate accounts investing in the Portfolios. Janus Capital
intends to monitor such qualified plans and the Portfolios may
discontinue sales to a qualified plan and require plan participants
with existing investments in the Portfolios to redeem those
investments if a plan loses (or in the opinion of Janus Capital is at
risk of losing) its qualified plan status.

YEAR 2000

Preparing for Year 2000 is a high priority for Janus Capital, which
has established a dedicated group to address this issue. Janus Capital
has devoted considerable internal resources and has engaged one of the
foremost experts in the field to help achieve Year 2000 readiness.
Janus Capital does not anticipate that Year 2000-related issues will
have a material impact on its ability to continue to provide the
Portfolios with service at current levels; however, Janus Capital
cannot make any assurances that the steps it has taken to ensure Year
2000 readiness will be successful. In addition, there can be no
assurance that Year 2000 issues will not affect the companies in which
the Portfolios invest or worldwide markets and economies.

14 Janus Aspen Series
<PAGE>
Distributions and taxes

DISTRIBUTIONS

To avoid taxation of the Portfolios, the Internal Revenue Code
requires each Portfolio to distribute net income and any net gains
realized on its investments annually. A Portfolio's income from
dividends and interest and any net realized short-term gains are paid
to shareholders as ordinary income dividends. Net realized long-term
gains are paid to shareholders as capital gains distributions.

Each class of each Portfolio makes semi-annual distributions in June
and December of substantially all of its investment income and an
annual distribution in June of its net realized gains, if any. All
dividends and capital gains distributions from Shares of a Portfolio
will automatically be reinvested into additional Shares of that
Portfolio.

HOW DISTRIBUTIONS AFFECT NAV

Distributions, other than daily income dividends, are paid to
shareholders as of the record date of the distribution of a Portfolio,
regardless of how long the shares have been held. Undistributed income
and realized gains are included in the daily NAV of a Portfolio's
Shares. The Share price of a Portfolio drops by the amount of the
distribution, net of any subsequent market fluctuations. For example,
assume that on December 31, the Shares of Global Life Sciences
Portfolio declared a dividend in the amount of $0.25 per share. If the
price of Global Life Sciences Portfolio's Shares was $10.00 on
December 30, the share price on December 31 would be $9.75, barring
market fluctuations.

TAXES

TAXES ON DISTRIBUTIONS

Because Shares of the Portfolios may be purchased only through
variable insurance contracts and qualified plans, it is anticipated
that any income dividends or capital gains distributions made by the
Shares of a Portfolio will be exempt from current taxation if left to
accumulate within the variable insurance contract or qualified plan.
Generally, withdrawals from such contracts may be subject to ordinary
income tax and, if made before age 59 1/2, a 10% penalty tax. The tax
status of your investment depends on the features of your qualified
plan or variable insurance contract. Further information may be found
in your plan documents or in the prospectus of the separate account
offering such contract.

TAXATION OF THE PORTFOLIOS

Dividends, interest and some gains received by the Portfolios on
foreign securities may be subject to withholding of foreign taxes. The
Portfolios may from year to year make the election permitted under
Section 853 of the Internal Revenue Code to pass through such taxes to
shareholders. If such election is not made, any foreign taxes paid or
accrued will represent an expense to the Portfolios which will reduce
their investment income.

The Portfolios do not expect to pay any federal income or excise taxes
because they intend to meet certain requirements of the Internal
Revenue Code. In addition, each Portfolio intends to qualify under the
Internal Revenue Code with respect to the diversification requirements
related to the tax-deferred status of insurance company separate
accounts.

Distributions and taxes 15
<PAGE>
Shareholder's guide

INVESTORS MAY NOT PURCHASE OR REDEEM SHARES OF THE PORTFOLIOS
DIRECTLY. SHARES MAY BE PURCHASED OR REDEEMED ONLY THROUGH VARIABLE
INSURANCE CONTRACTS OFFERED BY THE SEPARATE ACCOUNTS OF PARTICIPATING
INSURANCE COMPANIES OR THROUGH QUALIFIED RETIREMENT PLANS. CERTAIN
PORTFOLIOS MAY NOT BE AVAILABLE IN CONNECTION WITH A PARTICULAR
CONTRACT AND CERTAIN CONTRACTS MAY LIMIT ALLOCATIONS AMONG THE
PORTFOLIOS. REFER TO THE PROSPECTUS FOR THE PARTICIPATING INSURANCE
COMPANY'S SEPARATE ACCOUNT OR YOUR PLAN DOCUMENTS FOR INSTRUCTIONS ON
PURCHASING OR SELLING OF VARIABLE INSURANCE CONTRACTS AND ON HOW TO
SELECT SPECIFIC PORTFOLIOS AS INVESTMENT OPTIONS FOR A CONTRACT OR A
QUALIFIED PLAN.

PRICING OF PORTFOLIO SHARES

Investments will be processed at the NAV next determined after an
order is received and accepted by a Portfolio or its agent. In order
to receive a day's price, your order must be received by the close of
the regular trading session of the New York Stock Exchange any day
that the NYSE is open. Securities of the Portfolios are valued at
market value or, if a market quotation is not readily available, at
their fair value determined in good faith under procedures established
by and under the supervision of the Trustees. Short-term instruments
maturing within 60 days are valued at amortized cost, which
approximates market value. See the SAI for more detailed information.

To the extent a Portfolio holds securities that are primarily listed
on foreign exchanges that trade on weekends or other days when the
Portfolios do not price their shares, the NAV of a Portfolio's shares
may change on days when shareholders will not be able to purchase or
redeem the Portfolio's shares.

PURCHASES

Purchases of Shares may be made only by the separate accounts of
insurance companies for the purpose of funding variable insurance
contracts or by qualified plans. Refer to the prospectus of the
appropriate insurance company separate account or your plan documents
for information on how to invest in the Shares of each Portfolio.
Participating insurance companies and certain other designated
organizations are authorized to receive purchase orders on the
Portfolios' behalf.

Each Portfolio reserves the right to reject any specific purchase
order. Purchase orders may be refused if, in Janus Capital's opinion,
they are of a size that would disrupt the management of a Portfolio.
Although there is no present intention to do so, the Portfolios may
discontinue sales of their shares if management and the Trustees
believe that continued sales may adversely affect a Portfolio's
ability to achieve its investment objective. If sales of a Portfolio's
Shares are discontinued, it is expected that existing policy owners
and plan participants invested in that Portfolio would be permitted to
continue to authorize investment in that Portfolio and to reinvest any
dividends or capital gains distributions, absent highly unusual
circumstances.

REDEMPTIONS

Redemptions, like purchases, may be effected only through the separate
accounts of participating insurance companies or through qualified
plans. Please refer to the appropriate separate account prospectus or
plan documents for details.

Shares of any Portfolio may be redeemed on any business day.
Redemptions are processed at the NAV next calculated after receipt and
acceptance of the redemption order by the Portfolio or its agent.
Redemption proceeds will normally be wired to the participating
insurance company the business day following receipt of the redemption
order, but in no event later than seven days after receipt of such
order.

16 Janus Aspen Series
<PAGE>

SHAREHOLDER COMMUNICATIONS

Shareholders will receive annual and semiannual reports including the
financial statements of the Shares of the Portfolios that they have
authorized for investment. Each report will show the investments owned
by each Portfolio and the market values thereof, as well as other
information about the Portfolios and their operations. The Trust's
fiscal year ends December 31.

Shareholder's guide 17
<PAGE>
Financial highlights

No Financial Highlights are presented because the Portfolios did not
commence operations until January 15, 2000.

18 Janus Aspen Series
<PAGE>
Glossary of investment terms

This glossary provides a more detailed description of some of the
types of securities and other instruments in which the Portfolios may
invest. The Portfolios may invest in these instruments to the extent
permitted by their investment objectives and policies. The Portfolios
are not limited by this discussion and may invest in any other types
of instruments not precluded by the policies discussed elsewhere in
this Prospectus. Please refer to the SAI for a more detailed
discussion of certain instruments.

I. EQUITY AND DEBT SECURITIES

BONDS are debt securities issued by a company, municipality,
government or government agency. The issuer of a bond is required to
pay the holder the amount of the loan (or par value of the bond) at a
specified maturity and to make scheduled interest payments.

COMMERCIAL PAPER is a short-term debt obligation with a maturity
ranging from 1 to 270 days issued by banks, corporations and other
borrowers to investors seeking to invest idle cash. The Portfolios may
purchase commercial paper issued in private placements under Section
4(2) of the Securities Act of 1933.

COMMON STOCKS are equity securities representing shares of ownership
in a company and usually carry voting rights and earns dividends.
Unlike preferred stock, dividends on common stock are not fixed but
are declared at the discretion of the issuer's board of directors.

CONVERTIBLE SECURITIES are preferred stocks or bonds that pay a fixed
dividend or interest payment and are convertible into common stock at
a specified price or conversion ratio.

DEBT SECURITIES are securities representing money borrowed that must
be repaid at a later date. Such securities have specific maturities
and usually a specific rate of interest or an original purchase
discount.

DEPOSITARY RECEIPTS are receipts for shares of a foreign-based
corporation that entitle the holder to dividends and capital gains on
the underlying security. Receipts include those issued by domestic
banks (American Depositary Receipts), foreign banks (Global or
European Depositary Receipts) and broker-dealers (depositary shares).

FIXED-INCOME SECURITIES are securities that pay a specified rate of
return. The term generally includes short-and long-term government,
corporate and municipal obligations that pay a specified rate of
interest or coupons for a specified period of time, and preferred
stock, which pays fixed dividends. Coupon and dividend rates may be
fixed for the life of the issue or, in the case of adjustable and
floating rate securities, for a shorter period.

HIGH-YIELD/HIGH-RISK SECURITIES are securities that are rated below
investment grade by the primary rating agencies (e.g., BB or lower by
Standard & Poor's and Ba or lower by Moody's). Other terms commonly
used to describe such securities include "lower rated bonds,"
"noninvestment grade bonds" and "junk bonds."

MORTGAGE- AND ASSET-BACKED SECURITIES are shares in a pool of
mortgages or other debt. These securities are generally pass-through
securities, which means that principal and interest payments on the
underlying securities (less servicing fees) are passed through to
shareholders on a pro rata basis. These securities involve prepayment
risk, which is the risk that the underlying mortgages or other debt
may be refinanced or paid off prior to their maturities during periods
of declining interest rates. In that case, a portfolio manager may
have to reinvest the proceeds from the securities at a lower rate.
Potential market gains on a security subject to prepayment risk may be
more limited than potential market gains on a comparable security that
is not subject to prepayment risk.

PASSIVE FOREIGN INVESTMENT COMPANIES (PFICS) are any foreign
corporations which generate certain amounts of passive income or hold
certain amounts of assets for the production of passive income.
Passive

Glossary of investment terms 19
<PAGE>

income includes dividends, interest, royalties, rents and annuities.
To avoid taxes and interest that the Portfolios must pay if these
investments are profitable, the Portfolios may make various elections
permitted by the tax laws. These elections could require that the
Portfolios recognize taxable income, which in turn must be
distributed, before the securities are sold and before cash is
received to pay the distributions.

PAY-IN-KIND BONDS are debt securities that normally give the issuer an
option to pay cash at a coupon payment date or give the holder of the
security a similar bond with the same coupon rate and a face value
equal to the amount of the coupon payment that would have been made.

PREFERRED STOCKS are equity securities that generally pay dividends at
a specified rate and have preference over common stock in the payment
of dividends and liquidation. Preferred stock generally does not carry
voting rights.

REPURCHASE AGREEMENTS involve the purchase of a security by a
Portfolio and a simultaneous agreement by the seller (generally a bank
or dealer) to repurchase the security from the Portfolio at a
specified date or upon demand. This technique offers a method of
earning income on idle cash. These securities involve the risk that
the seller will fail to repurchase the security, as agreed. In that
case, a Portfolio will bear the risk of market value fluctuations
until the security can be sold and may encounter delays and incur
costs in liquidating the security.

REVERSE REPURCHASE AGREEMENTS involve the sale of a security by a
Portfolio to another party (generally a bank or dealer) in return for
cash and an agreement by the Portfolio to buy the security back at a
specified price and time. This technique will be used primarily to
provide cash to satisfy unusually high redemption requests, or for
other temporary or emergency purposes.

RULE 144A SECURITIES are securities that are not registered for sale
to the general public under the Securities Act of 1933, but that may
be resold to certain institutional investors.

STANDBY COMMITMENTS are obligations purchased by a Portfolio from a
dealer that give the Portfolio the option to sell a security to the
dealer at a specified price.

STEP COUPON BONDS are debt securities that trade at a discount from
their face value and pay coupon interest. The discount from the face
value depends on the time remaining until cash payments begin,
prevailing interest rates, liquidity of the security and the perceived
credit quality of the issuer.

STRIP BONDS are debt securities that are stripped of their interest
(usually by a financial intermediary) after the securities are issued.
The market value of these securities generally fluctuates more in
response to changes in interest rates than interest-paying securities
of comparable maturity.

TENDER OPTION BONDS are generally long-term securities that are
coupled with an option to tender the securities to a bank,
broker-dealer or other financial institution at periodic intervals and
receive the face value of the bond. This type of security is commonly
used as a means of enhancing the security's liquidity.

U.S. GOVERNMENT SECURITIES include direct obligations of the U.S.
government that are supported by its full faith and credit. Treasury
bills have initial maturities of less than one year, Treasury notes
have initial maturities of one to ten years and Treasury bonds may be
issued with any maturity but generally have maturities of at least ten
years. U.S. government securities also include indirect obligations of
the U.S. government that are issued by federal agencies and government
sponsored entities. Unlike Treasury securities, agency securities
generally are not backed by the full faith and credit of the U.S.
government. Some agency securities are supported by the right of the
issuer to borrow from the Treasury, others are supported by the
discretionary authority of the U.S. government to purchase the
agency's obligations and others are supported only by the credit of
the sponsoring agency.

20 Janus Aspen Series
<PAGE>

VARIABLE AND FLOATING RATE SECURITIES have variable or floating rates
of interest and, under certain limited circumstances, may have varying
principal amounts. These securities pay interest at rates that are
adjusted periodically according to a specified formula, usually with
reference to some interest rate index or market interest rate. The
floating rate tends to decrease the security's price sensitivity to
changes in interest rates.

WARRANTS are securities, typically issued with preferred stock or
bonds, that give the holder the right to buy a proportionate amount of
common stock at a specified price, usually at a price that is higher
than the market price at the time of issuance of the warrant. The
right may last for a period of years or indefinitely.

WHEN-ISSUED, DELAYED DELIVERY AND FORWARD TRANSACTIONS generally
involve the purchase of a security with payment and delivery at some
time in the future - i.e., beyond normal settlement. The Portfolios do
not earn interest on such securities until settlement and bear the
risk of market value fluctuations in between the purchase and
settlement dates. New issues of stocks and bonds, private placements
and U.S. government securities may be sold in this manner.

ZERO COUPON BONDS are debt securities that do not pay regular interest
at regular intervals, but are issued at a discount from face value.
The discount approximates the total amount of interest the security
will accrue from the date of issuance to maturity. The market value of
these securities generally fluctuates more in response to changes in
interest rates than interest-paying securities.

II. FUTURES, OPTIONS AND OTHER DERIVATIVES

FORWARD CONTRACTS are contracts to purchase or sell a specified amount
of a financial instrument for an agreed upon price at a specified
time. Forward contracts are not currently exchange traded and are
typically negotiated on an individual basis. The Portfolios may enter
into forward currency contracts to hedge against declines in the value
of securities denominated in, or whose value is tied to, a currency
other than the U.S. dollar or to reduce the impact of currency
appreciation on purchases of such securities. They may also enter into
forward contracts to purchase or sell securities or other financial
indices.

FUTURES CONTRACTS are contracts that obligate the buyer to receive and
the seller to deliver an instrument or money at a specified price on a
specified date. The Portfolios may buy and sell futures contracts on
foreign currencies, securities and financial indices including
interest rates or an index of U.S. government, foreign government,
equity or fixed-income securities. The Portfolios may also buy options
on futures contracts. An option on a futures contract gives the buyer
the right, but not the obligation, to buy or sell a futures contract
at a specified price on or before a specified date. Futures contracts
and options on futures are standardized and traded on designated
exchanges.

INDEXED/STRUCTURED SECURITIES are typically short- to
intermediate-term debt securities whose value at maturity or interest
rate is linked to currencies, interest rates, equity securities,
indices, commodity prices or other financial indicators. Such
securities may be positively or negatively indexed (i.e. their value
may increase or decrease if the reference index or instrument
appreciates). Indexed/structured securities may have return
characteristics similar to direct investments in the underlying
instruments and may be more volatile than the underlying instruments.
A Portfolio bears the market risk of an investment in the underlying
instruments, as well as the credit risk of the issuer.

INTEREST RATE SWAPS involve the exchange by two parties of their
respective commitments to pay or receive interest (e.g., an exchange
of floating rate payments for fixed rate payments).

INVERSE FLOATERS are debt instruments whose interest rate bears an
inverse relationship to the interest rate on another instrument or
index. For example, upon reset the interest rate payable on a security
may go down when the underlying index has risen. Certain inverse
floaters may have an interest rate reset

Glossary of investment terms 21
<PAGE>

mechanism that multiplies the effects of change in the underlying
index. Such mechanism may increase the volatility of the security's
market value.

OPTIONS are the right, but not the obligation, to buy or sell a
specified amount of securities or other assets on or before a fixed
date at a predetermined price. The Portfolios may purchase and write
put and call options on securities, securities indices and foreign
currencies.

22 Janus Aspen Series
<PAGE>

[JANUS LOGO]

1-800-525-0020

100 Fillmore Street
Denver, Colorado 80206-4928
janus.com

You can request other information, including a Statement of
Additional Information, free of charge, by contacting your insurance
company or plan sponsor or visiting our Web site at janus.com. Other
information is also available from financial intermediaries that
sell Shares of the Portfolios. The Statement of Additional
Information provides detailed information about the Portfolios and
is incorporated into this Prospectus by reference. You may review
the Portfolios' Statement of Additional Information at the Public
Reference Room of the SEC or get text only copies for a fee, by
writing to or calling the Public Reference Room, Washington, D.C.
20549-6009 (1-800-SEC-0330). You may obtain the Statement of
Additional Information for free from the SEC's Web site at
http://www.sec.gov.

Investment Company Act File No. 811-7736

PCAI0599
<PAGE>

[JANUS LOGO]

Subject to Completion

Preliminary Prospectus Dated November 1, 1999

Janus Aspen Series

Service Shares

PROSPECTUS

JANUARY 15, 2000

Global Life Sciences Portfolio

Global Technology Portfolio

[JANUS LOGO]

This prospectus describes two mutual funds (the "Portfolios")
which are series of Janus Aspen Series. Both of these Portfolios
offer two classes of shares. The Service Shares (the "Shares")
are offered by this prospectus in connection with investment in
and payments under variable annuity contracts and variable life
insurance contracts (collectively, "variable insurance
contracts"), as well as certain qualified retirement plans.

<PAGE>

Table of contents

<TABLE>
<S> <C>
RISK/RETURN SUMMARY
Global Life Sciences Portfolio........................... 2
Global Technology Portfolio.............................. 2
Fees and expenses........................................ 4
INVESTMENT OBJECTIVES, PRINCIPAL INVESTMENT STRATEGIES AND
RISKS
General portfolio policies............................... 7
Risks for Global Life Sciences and Global Technology
Portfolios............................................... 9
Risks Common to both Portfolios..........................
Investment techniques....................................
MANAGEMENT OF THE PORTFOLIOS
Investment adviser....................................... 12
Management expenses and expense limits................... 12
Investment personnel..................................... 13
OTHER INFORMATION........................................... 14
DISTRIBUTIONS AND TAXES
Distributions............................................ 15
Taxes.................................................... 15
SHAREHOLDER'S GUIDE
Purchases................................................ 16
Redemptions.............................................. 16
Shareholder communications............................... 17
FINANCIAL HIGHLIGHTS........................................ 18
GLOSSARY
Glossary of investment terms............................. 19

</TABLE>

Table of contents 1
<PAGE>
Risk return summary

GLOBAL LIFE SCIENCES AND GLOBAL TECHNOLOGY PORTFOLIOS

The Growth Portfolios are designed for long-term investors who seek
growth of capital and who can tolerate the greater risks associated
with common stock investments.

1. WHAT ARE THE INVESTMENT OBJECTIVES OF THE GLOBAL LIFE SCIENCES AND GLOBAL
TECHNOLOGY PORTFOLIOS?

- --------------------------------------------------------------------------------

Global Life Sciences and Global Technology Portfolios seek long-term
growth of capital.

2. WHAT ARE THE MAIN INVESTMENT STRATEGIES OF THE PORTFOLIOS?

3. WHAT ARE THE MAIN RISKS OF INVESTING IN THE PORTFOLIOS?

An investment in these Portfolios is not a bank deposit and is not
insured or guaranteed by the Federal Deposit Insurance Corporation or
any other government agency.

2 Janus Aspen Series
<PAGE>

Risk return summary 3
<PAGE>

FEES AND EXPENSES

This table and example are designed to assist participants in
qualified plans that invest in the Shares of the Portfolios in
understanding the fees and expenses that you may pay as an investor in
the Shares. The information shown is based upon estimated annualized
expenses the Portfolios' Shares expect to incur during their initial
fiscal year. OWNERS OF VARIABLE INSURANCE CONTRACTS THAT INVEST IN THE
SHARES SHOULD REFER TO THE VARIABLE INSURANCE CONTRACT PROSPECTUS FOR
A DESCRIPTION OF FEES AND EXPENSES, AS THE TABLE AND EXAMPLE DO NOT
REFLECT DEDUCTIONS AT THE SEPARATE ACCOUNT LEVEL OR CONTRACT LEVEL FOR
ANY CHARGES THAT MAY BE INCURRED UNDER A CONTRACT.

Total Annual Fund
Total Annual Fund Operating
Distribution Operating Expenses Total Expenses
Management (12b-1) Other Without Waivers Waivers With Waivers
Fee Fees(1) Expenses or Reductions(2) and Reductions or Reductions(2)
<S> <C> <C> <C> <C> <C> <C>
Global Life Sciences Portfolio 0.75% 0.25% 0.30% 1.30% N/A 1.30%
Global Technology Portfolio 0.75% 0.25% 0.30% 1.30% 0.02% 1.28%
</TABLE>

- --------------------------------------------------------------------------------
(1) Long-term shareholders may pay more than the economic equivalent of
the maximum front-end sales charges permitted by the National
Association of Securities Dealers, Inc.

(2) All expenses are based on the estimated annualized expenses the Shares
expect to incur during their initial fiscal year and are stated both
with and without contractual waivers and fee reductions by Janus
Capital. Global Life Sciences and Global Technology Portfolios reduce
the Management Fee to the level of the corresponding Janus retail
fund. Other waivers, if applicable, are first applied against the
Management Fee and then against Other Expenses. Janus Capital has
agreed to continue the waivers and fee reductions until at least the
next annual renewal of the advisory agreement.

- --------------------------------------------------------------------------------

<TABLE>
<CAPTION>
1 Year 3 Years
------------------
<S> <C> <C>
Global Life Sciences Portfolio $132 $412
Global Technology Portfolio $130 $406
</TABLE>

4 Janus Aspen Series
<PAGE>
Investment objectives, principal investment
strategies and risks

Each of the Portfolios has a similar investment objective and similar
principal investment strategies to a Janus retail fund:

<TABLE>
<S> <C>
Global Life Sciences Portfolio Janus Global Life Sciences Fund
Global Technology Portfolio Janus Global Technology Fund
</TABLE>

GROWTH PORTFOLIOS

INVESTMENT OBJECTIVES AND PRINCIPAL INVESTMENT STRATEGIES

GLOBAL LIFE SCIENCES PORTFOLIO

GLOBAL TECHNOLOGY PORTFOLIO

a. Companies that the portfolio manager believes have or will develop
products, processes or services that will provide significant
technological advancements or improvements; and

b. Companies that the portfolio manager believes rely extensively on
technology in connection with their operations or services.

Investment objectives, principal investment strategies and risks 5
<PAGE>

The following questions and answers are designed to help you better understand
the Portfolios' principal investment strategies.

1. HOW ARE COMMON STOCKS SELECTED?

2. ARE THE SAME CRITERIA USED TO SELECT FOREIGN SECURITIES?

3. WHAT DOES "LIFE SCIENCE ORIENTATION" MEAN IN RELATION TO GLOBAL LIFE SCIENCES
PORTFOLIO?

4. HOW DOES GLOBAL TECHNOLOGY PORTFOLIO'S INDUSTRY POLICY DIFFER FROM THAT OF
GLOBAL LIFE SCIENCES PORTFOLIO?

6 Janus Aspen Series
<PAGE>

GENERAL PORTFOLIO POLICIES OF THE PORTFOLIOS

OTHER TYPES OF INVESTMENTS

- debt securities

- indexed/structured securities

- high-yield/high-risk securities (less than 35% of each Portfolio's
assets)

- options, futures, forwards and other types of derivatives for
hedging purposes or for non-hedging purposes such as seeking to
enhance return

- securities purchased on a when-issued, delayed delivery or forward
commitment basis

ILLIQUID INVESTMENTS
Each Portfolio may invest up to 15% of its net assets in illiquid
investments. An illiquid investment is a security or other position
that cannot be disposed of quickly in the normal course of business.
For example, some securities are not registered under U.S. securities
laws and cannot be sold to the U.S. public because of SEC regulations
(these are known as "restricted securities"). Under procedures adopted
by the Portfolios' Trustees, certain restricted securities may be
deemed liquid, and will not be counted toward this 15% limit.

Investment objectives, principal investment strategies and risks 7
<PAGE>

States. Other ways of investing in foreign securities include
depositary receipts or shares, and passive foreign investment
companies.

Global Technology Portfolio may invest in companies with relatively
short product cycles, for example 6-9 months. Consequently its
portfolio turnover may be more frequent. Increased portfolio turnover
may result in higher costs for brokerage commissions, dealer mark-ups
and other transaction costs and may also result in taxable capital
gains. Higher costs associated with increased portfolio turnover may
offset gains in a Portfolio's performance.

8 Janus Aspen Series
<PAGE>

RISKS FOR GLOBAL LIFE SCIENCES AND GLOBAL TECHNOLOGY PORTFOLIOS

The following questions and answers are designed to help you better understand
some of the risks of investing in the Portfolios.

1. THE FUNDS MAY INVEST IN SMALLER OR NEWER COMPANIES. DOES THIS CREATE ANY
SPECIAL RISKS?

2. HOW COULD THE PORTFOLIOS' INVESTMENTS IN FOREIGN SECURITIES AFFECT THEIR
PERFORMANCE?

Investment objectives, principal investment strategies and risks 9
<PAGE>

before delivery and delays may be encountered in settling securities
transactions. In some foreign markets, there may not be protection
against failure by other parties to complete transactions.

- TRANSACTION COSTS. Costs of buying, selling and holding foreign
securities, including brokerage, tax and custody costs, may be
higher than those involved in domestic transactions.

3. WHAT IS "INDUSTRY RISK"?

4. HOW DOES THE NONDIVERSIFIED STATUS OF THE PORTFOLIOS AFFECT THEIR RISK?

5. ARE THERE SPECIAL RISKS ASSOCIATED WITH INVESTMENTS IN HIGH-YIELD/HIGH-RISK
SECURITIES?

6. HOW DO THE PORTFOLIOS TRY TO REDUCE RISK?

10 Janus Aspen Series
<PAGE>

7. I'VE HEARD A LOT ABOUT HOW THE CHANGE TO THE YEAR 2000 COULD AFFECT COMPUTER
SYSTEMS. DOES THIS CREATE ANY SPECIAL RISKS?

Investment objectives, principal investment strategies and risks 11
<PAGE>
Management of the portfolios

INVESTMENT ADVISER

Participating insurance companies that purchase the Portfolios' Shares
may perform administrative services relating to the Portfolios and
Janus Capital or the Portfolios may pay those companies for such
services.

MANAGEMENT EXPENSES AND EXPENSE LIMITS

Each Portfolio pays Janus Capital a management fee which is calculated
daily. The advisory agreement with each Portfolio spells out the
management fee and other expenses that the Portfolios must pay. Each
of the Portfolios is subject to the following management fee schedule
(expressed as an annual rate). In addition, the Shares of each
Portfolio incur expenses not assumed by Janus Capital, including the
distribution fee, transfer agent and custodian fees and expenses,
legal and auditing fees, printing and mailing costs of sending reports
and other information to existing shareholders, and independent
Trustees' fees and expenses.

<TABLE>
<CAPTION>
Average Daily
Net Assets Annual Rate Expense Limit
Fee Schedule of Portfolio Percentage (%) Percentage (%)
- ------------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C>
Global Life Sciences Portfolio First $300 Million 0.75 1.25(1)(2)
Global Technology Portfolio Next $200 Million 0.70
Over $500 Million 0.65
- ------------------------------------------------------------------------------------------------------------------
</TABLE>

(1) Janus Capital has agreed to reduce Global Life Sciences and Global
Technology Portfolio's management fee to the extent that such fee exceeds
the effective rate of the Janus retail fund corresponding to such Portfolio.
Janus Capital has agreed to continue such waivers until at least the next
annual renewal of the advisory agreements. The effective rate is the
management fee calculated by the corresponding retail fund as of the last
day of each calendar quarter (expressed as an annual rate). The effective
rates of Janus Global Life Sciences Fund and Janus Global Technology Fund
were . % and . %, respectively, for the quarter ended December 31, 1999.

(2) Janus Capital has agreed to limit the Portfolios' expenses as indicated
until at least the next annual renewal of the advisory contracts. The
distribution fee described on page 14 is not included in the expense limit.

12 Janus Aspen Series
<PAGE>

INVESTMENT PERSONNEL

PORTFOLIO MANAGERS

C. MIKE LU

- --------------------------------------------------------------------------------

THOMAS R. MALLEY

- --------------------------------------------------------------------------------

Management of the portfolios 13
<PAGE>
Other information

CLASSES OF SHARES

Each Portfolio offers two classes of shares, one of which, the Service
Shares, are offered pursuant to this prospectus. The Shares offered by
this prospectus are available only in connection with investment in
and payments under variable insurance contracts as well as certain
qualified retirement plans. Institutional shares of each portfolio are
offered by separate prospectus. Because the expenses of each class may
differ, the performance of each class is expected to differ. If you
would like additional information about the Institutional Shares,
please call 1-800-525-0020.

DISTRIBUTION FEE

Under a distribution and service plan adopted in accordance with Rule
12b-1 under the 1940 Act, the Shares may pay Janus Distributors, Inc.,
the Trust's distributor, a fee at an annual rate of up to 0.25% of the
average daily net assets of the Shares of a Portfolio. Under the terms
of the Plan, the Trust is authorized to make payments to Janus
Distributors for remittance to insurance companies and qualified plan
service providers as compensation for distribution and shareholder
servicing performed by such entities. Because 12b-1 fees are paid out
of the Service Shares' assets on an ongoing basis, they will increase
the cost of your investment and may cost you more than paying other
types of sales charges.

CONFLICTS OF INTEREST

The Trust's shares are available only to variable annuity and variable
life separate accounts of insurance companies that are unaffiliated
with Janus Capital and to certain qualified retirement plans. Although
the Portfolios do not currently anticipate any disadvantages to owners
of variable insurance contracts because each Portfolio offers its
shares to such entities, there is a possibility that a material
conflict may arise. The Trustees monitor events in order to identify
any disadvantages or material irreconcilable conflicts and to
determine what action, if any, should be taken in response. If a
material disadvantage or conflict occurs, the Trustees may require one
or more insurance company separate accounts or qualified plans to
withdraw its investments in one or more Portfolios or substitute
shares of another Portfolio. If this occurs, a Portfolio may be forced
to sell its securities at disadvantageous prices. In addition, the
Trustees may refuse to sell shares of any Portfolio to any separate
account or qualified plan or may suspend or terminate the offering of
a Portfolio's shares if such action is required by law or regulatory
authority or is in the best interests of that Portfolio's
shareholders. It is possible that a qualified plan investing in the
Portfolios could lose its qualified plan status under the Internal
Revenue Code, which could have adverse tax consequences on insurance
company separate accounts investing in the Portfolios. Janus Capital
intends to monitor such qualified plans and the Portfolios may
discontinue sales to a qualified plan and require plan participants
with existing investments in the Portfolios to redeem those
investments if a plan loses (or in the opinion of Janus Capital is at
risk of losing) its qualified plan status.

YEAR 2000

14 Janus Aspen Series
<PAGE>
Distributions and taxes

DISTRIBUTIONS

HOW DISTRIBUTIONS AFFECT NAV

TAXES

TAXES ON DISTRIBUTIONS

Because Shares of the Portfolios may be purchased only through
variable insurance contracts and qualified plans, it is anticipated
that any income dividends or capital gains distributions made by the
Shares of a Portfolio will be exempt from current taxation if left to
accumulate within the variable insurance contract or qualified plan.
Generally, withdrawals from such contracts or plans may be subject to
ordinary income tax and, if made before age 59 1/2, a 10% penalty tax.
The tax status of your investment depends on the features of your
qualified plan or variable insurance contract. Further information may
be found in your plan documents or in the prospectus of the separate
account offering such contract.

TAXATION OF THE PORTFOLIOS

The Portfolios do not expect to pay any federal income or excise taxes
because they intend to meet certain requirements of the Internal
Revenue Code. In addition, because a class of shares of each Portfolio
are sold in connection with variable annuity contracts and variable
life insurance contracts, each Portfolio intends to qualify under the
Internal Revenue Code with respect to the diversification requirements
related to the tax-deferred status of insurance company separate
accounts.

Distributions and taxes 15
<PAGE>
Shareholder's guide

PRICING OF PORTFOLIO SHARES

PURCHASES

Each Portfolio reserves the right to reject any specific purchase
order. Purchase orders may be refused if, in Janus Capital's opinion,
they are of a size that would disrupt the management of a Portfolio.
Although there is no present intention to do so, the Portfolios may
discontinue sales of their shares if management and the Trustees
believe that continued sales may adversely affect a Portfolio's
ability to achieve its investment objective. If sales of a Portfolio's
Shares are discontinued, it is expected that existing participants
invested in that Portfolio would be permitted to continue to authorize
investment in that Portfolio and to reinvest any dividends or capital
gains distributions, absent highly unusual circumstances. The
Portfolios may discontinue sales to a qualified plan and require plan
participants with existing investments in the Shares to redeem those
investments if the plan loses (or in the opinion of Janus Capital, is
at risk of losing) its qualified plan status.

REDEMPTIONS

16 Janus Aspen Series
<PAGE>

proceeds will normally be wired the business day following receipt of
the redemption order, but in no event later than seven days after
receipt of such order.

SHAREHOLDER COMMUNICATIONS

Shareholder's guide 17
<PAGE>
Financial highlights

No Financial Highlights are presented because the Portfolios did not
commence operations until January 15, 2000.

18 Janus Aspen Series
<PAGE>
Glossary of investment terms

I. EQUITY AND DEBT SECURITIES

CONVERTIBLE SECURITIES are preferred stocks or bonds that pay a fixed
dividend or interest payment and are convertible into common stock at
a specified price or conversion ratio.

Glossary of investment terms 19
<PAGE>

RULE 144A SECURITIES are securities that are not registered for sale
to the general public under the Securities Act of 1933, but that may
be resold to certain institutional investors.

STANDBY COMMITMENTS are obligations purchased by a Portfolio from a
dealer that give the Portfolio the option to sell a security to the
dealer at a specified price.

20 Janus Aspen Series
<PAGE>

II. FUTURES, OPTIONS AND OTHER DERIVATIVES

INTEREST RATE SWAPS involve the exchange by two parties of their
respective commitments to pay or receive interest (e.g., an exchange
of floating rate payments for fixed rate payments).

Glossary of investment terms 21
<PAGE>

mechanism that multiplies the effects of change in the underlying
index. Such mechanism may increase the volatility of the security's
market value.

22 Janus Aspen Series
<PAGE>

[JANUS LOGO]

1-800-525-0020

100 Fillmore Street
Denver, Colorado 80206-4928
janus.com

You can request other information, including a Statement of
Additional Information, free of charge, by contacting your plan
sponsor or visiting our Web site at janus.com. Other information is
also available from financial intermediaries that sell Shares of the
Portfolios. The Statement of Additional Information provides
detailed information about the Portfolios and is incorporated into
this Prospectus by reference. You may review the Portfolios'
Statement of Additional Information at the Public Reference Room of
the SEC or get text only copies for a fee, by writing to or calling
the Public Reference Room, Washington, D.C. 20549-6009
(1-800-SEC-0330). You may obtain the Statement of Additional
Information for free from the SEC's Web site at http://www.sec.gov.

Investment Company Act File No. 811-7736

<PAGE>

LOGO

1-800-525-0020

100 Fillmore Street
Denver, Colorado 80206-4928
janus.com

<PAGE>

The information in this Statement of Additional Information is not complete and
may be changed. We may not sell these securities until the registration
statement filed with the Securities and Exchange Commission is effective. This
Statement of Additional Information is not an offer to sell these securities and
is not soliciting an offer to buy these securities in any state where the offer
is not permitted.

LOGO

Subject to Completion

Preliminary Statement of Additional Information Dated
November 1, 1999

Janus Aspen Series

Global Life Sciences Portfolio

Global Technology Portfolio

100 Fillmore Street
Denver, CO 80206-4928

(800) 525-0020

Statement of Additional Information

January 15, 2000

This Statement of Additional Information expands upon and
supplements the information contained in the current Prospectus
for the Institutional Shares (the "Shares") of the portfolios
listed above, each of which is a separate series of Janus Aspen
Series, a Delaware business trust. The Shares are sold under
the name "Janus Aspen Series." Each of these series of the
Trust represents shares of beneficial interest in a separate
portfolio of securities and other assets with its own objective
and policies. Each Portfolio is managed separately by Janus
Capital Corporation.

The Shares of the Portfolios may be purchased only by the
separate accounts of insurance companies for the purpose of
funding variable life insurance policies and variable annuity
contracts (collectively, "variable insurance contracts") and by
certain qualified retirement plans. Each Portfolio also offers
a second class of shares to certain participant directed
qualified plans.

This SAI is not a Prospectus and should be read in conjunction
with the Portfolios' Prospectus dated January 15, 2000, which
is incorporated by reference into this SAI and may be obtained
from your insurance company. This SAI contains additional and
more detailed information about the Portfolios' operations and
activities than the Prospectus. The Annual Reports, which
contain important financial information about the Portfolios,
are incorporated by reference into this SAI and are also
available, without charge, from your insurance company.

<PAGE>

LOGO
<PAGE>
Table of contents

<TABLE>
<S> <C>
Classification, Portfolio Turnover, Investment Policies and
Restrictions, and Investment Strategies and Risks........... 2
Investment Adviser.......................................... 21
Custodian, Transfer Agent and Certain Affiliations.......... 23
Portfolio Transactions and Brokerage........................ 24
Trustees and Officers....................................... 26
Shares of the Trust......................................... 30
Net Asset Value Determination............................ 30
Purchases................................................ 30
Redemptions.............................................. 31
Income Dividends, Capital Gains Distributions and Tax
Status...................................................... 32
Miscellaneous Information................................... 33
Shares of the Trust...................................... 33
Shareholder Meetings..................................... 33
Voting Rights............................................ 33
Independent Accountants.................................. 34
Registration Statement................................... 34
Performance Information..................................... 35
Appendix A.................................................. 36
Explanation of Rating Categories......................... 36
</TABLE>

1
<PAGE>
Classification, portfolio turnover, investment policies
and restrictions, and investment
strategies and risks

CLASSIFICATION

Each Portfolio is a series of the Trust, an open-end, management
investment company. The Investment Company Act of 1940 ("1940 Act")
classifies mutual funds as either diversified or nondiversified.
Global Life Sciences Portfolio and Global Technology Portfolio are
nondiversified funds. Both of these Portfolios reserve the right to
become a diversified fund by limiting the investments in which more
than 5% of its total assets are invested.

PORTFOLIO TURNOVER

The Prospectus includes a discussion of portfolio turnover policies.
Portfolio turnover is calculated by dividing total purchases or sales,
whichever is less, by the average monthly value of a Portfolio's
securities.

INVESTMENT POLICIES AND RESTRICTIONS

The Portfolios are subject to certain fundamental policies and
restrictions that may not be changed without shareholder approval.
Shareholder approval means approval by the lesser of (i) more than 50%
of the outstanding voting securities of the Trust (or a particular
Portfolio or particular class of shares if a matter affects just that
Portfolio or that class of shares), or (ii) 67% or more of the voting
securities present at a meeting if the holders of more than 50% of the
outstanding voting securities of the Trust (or a particular Portfolio
or class of shares) are present or represented by proxy. As
fundamental policies, each of the Portfolios may not:

(1) Own more than 10% of the outstanding voting securities of any one
issuer and, as to fifty percent (50%) of the value of the total
assets, purchase the securities of any one issuer (except cash items
and "government securities" as defined under the Investment Company
Act of 1940, as amended), if immediately after and as a result of such
purchase, the value of the holdings of a Portfolio in the securities
of such issuer exceeds 5% of the value of such Portfolio's total
assets. With respect to the other 50% of the value of their total
assets, the Portfolios may invest in the securities of as few as two
issuers.

(2) Invest directly in real estate or interests in real estate;
however, the Portfolios may own debt or equity securities issued by
companies engaged in those businesses.

(3) Purchase or sell physical commodities other than foreign
currencies unless acquired as a result of ownership of securities (but
this limitation shall not prevent the Portfolios from purchasing or
selling options, futures, swaps and forward contracts or from
investing in securities or other instruments backed by physical
commodities).

(4) Lend any security or make any other loan if, as a result, more
than 25% of a Portfolio's total assets would be lent to other parties
(but this limitation does not apply to purchases of commercial paper,
debt securities or repurchase agreements).

(5) Act as an underwriter of securities issued by others, except to
the extent that a Portfolio may be deemed an underwriter in connection
with the disposition of its portfolio securities.

As a fundamental policy, Global Life Sciences Portfolio will normally
invest at least 25% of its total assets, in the aggregate, in the
following industry groups: health care; pharmaceuticals; agriculture;
cosmetics/personal care; and biotechnology. Global Technology
Portfolio will not invest 25% or more of the value of its total assets
in any particular industry (other than U.S. government securities).

As a fundamental policy, each Portfolio may, notwithstanding any other
investment policy or limitation (whether or not fundamental), invest
all of its assets in the securities of a single open-end management

2
<PAGE>

investment company with substantially the same fundamental investment
objective, policies and limitations as such Portfolio.

The Trustees have adopted additional investment restrictions for the
Portfolios. These restrictions are operating policies of the
Portfolios and may be changed by the Trustees without shareholder
approval. The additional investment restrictions adopted by the
Trustees to date include the following:

(a) A Portfolio will not (i) enter into any futures contracts and
related options for purposes other than bona fide hedging transactions
within the meaning of Commodity Futures Trading Commission ("CFTC")
regulations if the aggregate initial margin and premiums required to
establish positions in futures contracts and related options that do
not fall within the definition of bona fide hedging transactions will
exceed 5% of the fair market value of a Portfolio's net assets, after
taking into account unrealized profits and unrealized losses on any
such contracts it has entered into; and (ii) enter into any futures
contracts if the aggregate amount of such Portfolio's commitments
under outstanding futures contracts positions would exceed the market
value of its total assets.

(b) The Portfolios do not currently intend to sell securities short,
unless they own or have the right to obtain securities equivalent in
kind and amount to the securities sold short without the payment of
any additional consideration therefor, and provided that transactions
in futures, options, swaps and forward contracts are not deemed to
constitute selling securities short.

(c) The Portfolios do not currently intend to purchase securities on
margin, except that the Portfolios may obtain such short-term credits
as are necessary for the clearance of transactions, and provided that
margin payments and other deposits in connection with transactions in
futures, options, swaps and forward contracts shall not be deemed to
constitute purchasing securities on margin.

(d) A Portfolio may not mortgage or pledge any securities owned or
held by such Portfolio in amounts that exceed, in the aggregate, 15%
of that Portfolio's net asset value, provided that this limitation
does not apply to reverse repurchase agreements, deposits of assets to
margin, guarantee positions in futures, options, swaps or forward
contracts, or the segregation of assets in connection with such
contracts.

(e) The Portfolios may borrow money for temporary or emergency
purposes (not for leveraging or investment) in an amount not exceeding
25% of the value of their respective total assets (including the
amount borrowed) less liabilities (other than borrowings). If
borrowings exceed 25% of the value of a Portfolio's total assets by
reason of a decline in net assets, the Portfolio will reduce its
borrowings within three business days to the extent necessary to
comply with the 25% limitation. This policy shall not prohibit reverse
repurchase agreements, deposits of assets to margin or guarantee
positions in futures, options, swaps or forward contracts, or the
segregation of assets in connection with such contracts.

(f) The Portfolios do not currently intend to purchase any security or
enter into a repurchase agreement, if as a result, more than 15% of
their respective net assets would be invested in repurchase agreements
not entitling the holder to payment of principal and interest within
seven days and in securities that are illiquid by virtue of legal or
contractual restrictions on resale or the absence of a readily
available market. The Trustees, or the Portfolios' investment adviser
acting pursuant to authority delegated by the Trustees, may determine
that a readily available market exists for securities eligible for
resale pursuant to Rule 144A under the Securities Act of 1933 ("Rule
144A Securities"), or any successor to such rule, Section 4(2)
commercial paper and municipal lease obligations. Accordingly, such
securities may not be subject to the foregoing limitation.

(g) The Portfolios may not invest in companies for the purpose of
exercising control of management.

3
<PAGE>

Under the terms of an exemptive order received from the Securities and
Exchange Commission ("SEC"), each of the Portfolios may borrow money
from or lend money to other funds that permit such transactions and
for which Janus Capital serves as investment adviser. All such
borrowing and lending will be subject to the above limits. A Portfolio
will borrow money through the program only when the costs are equal to
or lower than the cost of bank loans. Interfund loans and borrowings
normally extend overnight, but can have a maximum duration of seven
days. A Portfolio will lend through the program only when the returns
are higher than those available from other short-term instruments
(such as repurchase agreements). A Portfolio may have to borrow from a
bank at a higher interest rate if an interfund loan is called or not
renewed. Any delay in repayment to a lending Portfolio could result in
a lost investment opportunity or additional borrowing costs.

For purposes of the Portfolios' restriction on investing in a
particular industry, the Portfolios will rely primarily on industry
classifications as published by Bloomberg L.P. To the extent that
Bloomberg L.P. classifications are so broad that the primary economic
characteristics in a single class are materially different, the
Portfolios may further classify issuers in accordance with industry
classifications as published by the SEC.

4
<PAGE>

INVESTMENT STRATEGIES AND RISKS

Cash Position

As discussed in the Prospectus, when a portfolio manager believes that
market conditions are unfavorable for profitable investing, or when he
or she is otherwise unable to locate attractive investment
opportunities, the Portfolio's investment in cash and similar
investments may increase. Securities that the Portfolios may invest in
as a means of receiving a return on idle cash include commercial
paper, certificates of deposit, repurchase agreements or other
short-term debt obligations. The Portfolios may also invest in money
market funds, including funds managed by Janus Capital. (See
"Investment Company Securities" on page 8).

Illiquid Investments

Each Portfolio may invest up to 15% of its net assets in illiquid
investments (i.e., securities that are not readily marketable). The
Trustees have authorized Janus Capital to make liquidity
determinations with respect to certain securities, including Rule 144A
Securities, commercial paper and municipal lease obligations purchased
by the Portfolios. Under the guidelines established by the Trustees,
Janus Capital will consider the following factors: (1) the frequency
of trades and quoted prices for the obligation; (2) the number of
dealers willing to purchase or sell the security and the number of
other potential purchasers; (3) the willingness of dealers to
undertake to make a market in the security; and (4) the nature of the
security and the nature of the marketplace trades, including the time
needed to dispose of the security, the method of soliciting offers and
the mechanics of the transfer. In the case of commercial paper, Janus
Capital will also consider whether the paper is traded flat or in
default as to principal and interest and any ratings of the paper by a
nationally recognized statistical rating organization ("NRSRO"). A
foreign security that may be freely traded on or through the
facilities of an offshore exchange or other established offshore
securities market is not deemed to be a restricted security subject to
these procedures.

If illiquid securities exceed 15% of a Portfolio's net assets after
the time of purchase the Portfolio will take steps to reduce in an
orderly fashion its holdings of illiquid securities. Because illiquid
securities may not be readily marketable, a portfolio manager may not
be able to dispose of them in a timely manner. As a result, a
Portfolio may be forced to hold illiquid securities while their price
depreciates. Depreciation in the price of illiquid securities may
cause the net asset value of a Portfolio to decline.

Securities Lending

The Portfolios may lend securities to qualified parties (typically
brokers or other financial institutions) who need to borrow securities
in order to complete certain transactions such as covering short
sales, avoiding failures to deliver securities or completing arbitrage
activities. The Portfolios may seek to earn additional income through
securities lending. Since there is the risk of delay in recovering a
loaned security or the risk of loss in collateral rights if the
borrower fails financially, securities lending will only be made to
parties that Janus Capital deems creditworthy and in good standing. In
addition, such loans will only be made if Janus Capital believes the
benefit from granting such loans justifies the risk. The Portfolios
will not have the right to vote on securities while they are being
lent, but they will call a loan in anticipation of any important vote.
All loans will be continuously secured by collateral which consists of
cash, U.S. government securities, letters of credit and such other
collateral permitted by the Securities and Exchange Commission and
policies approved by the Trustees. Cash collateral may be invested in
money market funds advised by Janus Capital to the extent consistent
with exemptive relief obtained from the Securities and Exchange
Commission.

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Short Sales

Each Portfolio may engage in "short sales against the box." This
technique involves selling either a security that a Portfolio owns, or
a security equivalent in kind and amount to the security sold short
that the Portfolio has the right to obtain, for delivery at a
specified date in the future. A Portfolio may enter into a short sale
against the box to hedge against anticipated declines in the market
price of portfolio securities. If the value of the securities sold
short increases prior to the scheduled delivery date, a Portfolio
loses the opportunity to participate in the gain.

Zero Coupon, Step Coupon and Pay-In-Kind Securities

Each Portfolio may invest up to 10% of its assets in zero coupon,
pay-in-kind and step coupon securities. Zero coupon bonds are issued
and traded at a discount from their face value. They do not entitle
the holder to any periodic payment of interest prior to maturity. Step
coupon bonds trade at a discount from their face value and pay coupon
interest. The coupon rate is low for an initial period and then
increases to a higher coupon rate thereafter. The discount from the
face amount or par value depends on the time remaining until cash
payments begin, prevailing interest rates, liquidity of the security
and the perceived credit quality of the issuer. Pay-in-kind bonds
normally give the issuer an option to pay cash at a coupon payment
date or give the holder of the security a similar bond with the same
coupon rate and a face value equal to the amount of the coupon payment
that would have been made. For the purposes of any Portfolio's
restriction on investing in income-producing securities,
income-producing securities include securities that make periodic
interest payments as well as those that make interest payments on a
deferred basis or pay interest only at maturity (e.g., Treasury bills
or zero coupon bonds).

Current federal income tax law requires holders of zero coupon
securities and step coupon securities to report the portion of the
original issue discount on such securities that accrues during a given
year as interest income, even though the holders receive no cash
payments of interest during the year. In order to qualify as a
"regulated investment company" under the Internal Revenue Code of 1986
and the regulations thereunder (the "Code"), a Portfolio must
distribute its investment company taxable income, including the
original issue discount accrued on zero coupon or step coupon bonds.
Because a Portfolio will not receive cash payments on a current basis
in respect of accrued original-issue discount on zero coupon bonds or
step coupon bonds during the period before interest payments begin, in
some years that Portfolio may have to distribute cash obtained from
other sources in order to satisfy the distribution requirements under
the Code. A Portfolio might obtain such cash from selling other
portfolio holdings which might cause that Portfolio to incur capital
gains or losses on the sale. Additionally, these actions are likely to
reduce the assets to which Portfolio expenses could be allocated and
to reduce the rate of return for that Portfolio. In some
circumstances, such sales might be necessary in order to satisfy cash
distribution requirements even though investment considerations might
otherwise make it undesirable for a Portfolio to sell the securities
at the time.

Generally, the market prices of zero coupon, step coupon and
pay-in-kind securities are more volatile than the prices of securities
that pay interest periodically and in cash and are likely to respond
to changes in interest rates to a greater degree than other types of
debt securities having similar maturities and credit quality.

Pass-Through Securities

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pool of securities. The issuers of the underlying securities make
interest and principal payments to the intermediary which are passed
through to purchasers, such as the Portfolios. The most common type of
pass-through securities are mortgage-backed securities. Government
National Mortgage Association ("GNMA") Certificates are
mortgage-backed securities that evidence an undivided interest in a
pool of mortgage loans. GNMA Certificates differ from bonds in that
principal is paid back monthly by the borrowers over the term of the
loan rather than returned in a lump sum at maturity. A Portfolio will
generally purchase "modified pass-through" GNMA Certificates, which
entitle the holder to receive a share of all interest and principal
payments paid and owned on the mortgage pool, net of fees paid to the
"issuer" and GNMA, regardless of whether or not the mortgagor actually
makes the payment. GNMA Certificates are backed as to the timely
payment of principal and interest by the full faith and credit of the
U.S. government.

The Federal Home Loan Mortgage Corporation ("FHLMC") issues two types
of mortgage pass-through securities: mortgage participation
certificates ("PCs") and guaranteed mortgage certificates ("GMCs").
PCs resemble GNMA Certificates in that each PC represents a pro rata
share of all interest and principal payments made and owned on the
underlying pool. FHLMC guarantees timely payments of interest on PCs
and the full return of principal. GMCs also represent a pro rata
interest in a pool of mortgages. However, these instruments pay
interest semiannually and return principal once a year in guaranteed
minimum payments. This type of security is guaranteed by FHLMC as to
timely payment of principal and interest but it is not guaranteed by
the full faith and credit of the U.S. government.

The Federal National Mortgage Association ("FNMA") issues guaranteed
mortgage pass-through certificates ("FNMA Certificates"). FNMA
Certificates resemble GNMA Certificates in that each FNMA Certificate
represents a pro rata share of all interest and principal payments
made and owned on the underlying pool. This type of security is
guaranteed by FNMA as to timely payment of principal and interest but
it is not guaranteed by the full faith and credit of the U.S.
government.

Except for GMCs, each of the mortgage-backed securities described
above is characterized by monthly payments to the holder, reflecting
the monthly payments made by the borrowers who received the underlying
mortgage loans. The payments to the security holders (such as the
Portfolios), like the payments on the underlying loans, represent both
principal and interest. Although the underlying mortgage loans are for
specified periods of time, such as 20 or 30 years, the borrowers can,
and typically do, pay them off sooner. Thus, the security holders
frequently receive prepayments of principal in addition to the
principal that is part of the regular monthly payments. A portfolio
manager will consider estimated prepayment rates in calculating the
average-weighted maturity of a Portfolio. A borrower is more likely to
prepay a mortgage that bears a relatively high rate of interest. This
means that in times of declining interest rates, higher yielding
mortgage-backed securities held by a Portfolio might be converted to
cash and that Portfolio will be forced to accept lower interest rates
when that cash is used to purchase additional securities in the
mortgage-backed securities sector or in other investment sectors.
Additionally, prepayments during such periods will limit a Portfolio's
ability to participate in as large a market gain as may be experienced
with a comparable security not subject to prepayment.

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<PAGE>

or lease with a vendor. Such securities may be secured by the assets
purchased or leased by the municipality; however, if the municipality
stops making payments, there generally will be no recourse against the
vendor. The market for tax-exempt asset-backed securities is still
relatively new. These obligations are likely to involve unscheduled
prepayments of principal.

Investment Company Securities

From time to time, the Portfolios may invest in securities of other
investment companies, subject to the provisions of Section 12(d)(1) of
the 1940 Act. The Portfolios may invest in securities of money market
funds managed by Janus Capital in excess of the limitations of Section
12(d)(1) under the terms of an SEC exemptive order obtained by Janus
Capital and the Janus funds.

Depositary Receipts

The Portfolios may invest in sponsored and unsponsored American
Depositary Receipts ("ADRs"), which are receipts issued by an American
bank or trust company evidencing ownership of underlying securities
issued by a foreign issuer. ADRs, in registered form, are designed for
use in U.S. securities markets. Unsponsored ADRs may be created
without the participation of the foreign issuer. Holders of these ADRs
generally bear all the costs of the ADR facility, whereas foreign
issuers typically bear certain costs in a sponsored ADR. The bank or
trust company depositary of an unsponsored ADR may be under no
obligation to distribute shareholder communications received from the
foreign issuer or to pass through voting rights. The Portfolios may
also invest in European Depositary Receipts ("EDRs"), Global
Depositary Receipts ("GDRs") and in other similar instruments
representing securities of foreign companies. EDRs are receipts issued
by a European financial institution evidencing an arrangement similar
to that of ADRs. EDRs, in bearer form, are designed for use in
European securities markets. GDRs are securities convertible into
equity securities of foreign issuers. Depositary Receipts are
generally subject to the same sort of risks as direct investments in a
foreign country, such as, currency risk, political and economic risk,
and market risk, because their values depend on the performance of a
foreign security denominated in its home currency. The risks of
foreign investing are addressed in some detail in the Portfolios'
prospectus.

Municipal Obligations

The Portfolios may invest in municipal obligations issued by states,
territories and possessions of the United States and the District of
Columbia. The value of municipal obligations can be affected by
changes in their actual or perceived credit quality. The credit
quality of municipal obligations can be affected by, among other
things, the financial condition of the issuer or guarantor, the
issuer's future borrowing plans and sources of revenue, the economic
feasibility of the revenue bond project or general borrowing purpose,
political or economic developments in the region where the security is
issued, and the liquidity of the security. Because municipal
securities are generally traded over-the-counter, the liquidity of a
particular issue often depends on the willingness of dealers to make a
market in the security. The liquidity of some municipal obligations
may be enhanced by demand features, which would enable a Portfolio to
demand payment on short notice from the issuer or a financial
intermediary.

Other Income-Producing Securities

Other types of income producing securities that the Portfolios may
purchase include, but are not limited to, the following types of
securities:

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<PAGE>

to changes in interest rates. These types of securities are relatively
long-term instruments that often carry demand features permitting the
holder to demand payment of principal at any time or at specified
intervals prior to maturity. In order to most effectively use these
investments, a portfolio manager must correctly assess probable
movements in interest rates. This involves different skills than those
used to select most portfolio securities. If the portfolio manager
incorrectly forecasts such movements, a Portfolio could be adversely
affected by the use of variable or floating rate obligations.

STANDBY COMMITMENTS. These instruments, which are similar to a put,
give a Portfolio the option to obligate a broker, dealer or bank to
repurchase a security held by that Portfolio at a specified price.

TENDER OPTION BONDS. Tender option bonds are relatively long-term
bonds that are coupled with the agreement of a third party (such as a
broker, dealer or bank) to grant the holders of such securities the
option to tender the securities to the institution at periodic
intervals.

INVERSE FLOATERS. Inverse floaters are debt instruments whose interest
bears an inverse relationship to the interest rate on another
security. No Portfolio will invest more than 5% of its assets in
inverse floaters. Similar to variable and floating rate obligations,
effective use of inverse floaters requires skills different from those
needed to select most portfolio securities. If movements in interest
rates are incorrectly anticipated, a fund could lose money or its NAV
could decline by the use of inverse floaters.

STRIP BONDS. Strip bonds are debt securities that are stripped of
their interest (usually by a financial intermediary) after the
securities are issued. The market value of these securities generally
fluctuates more in response to changes in interest rates than
interest-paying securities of comparable maturity.

The Portfolios will purchase standby commitments, tender option bonds
and instruments with demand features primarily for the purpose of
increasing the liquidity of their holdings.

Repurchase and Reverse Repurchase Agreements

In a repurchase agreement, a Portfolio purchases a security and
simultaneously commits to resell that security to the seller at an
agreed upon price on an agreed upon date within a number of days
(usually not more than seven) from the date of purchase. The resale
price consists of the purchase price plus an agreed upon incremental
amount that is unrelated to the coupon rate or maturity of the
purchased security. A repurchase agreement involves the obligation of
the seller to pay the agreed upon price, which obligation is in effect
secured by the value (at least equal to the amount of the agreed upon
resale price and marked-to-market daily) of the underlying security or
"collateral." A risk associated with repurchase agreements is the
failure of the seller to repurchase the securities as agreed, which
may cause a Portfolio to suffer a loss if the market value of such
securities declines before they can be liquidated on the open market.
In the event of bankruptcy or insolvency of the seller, a Portfolio
may encounter delays and incur costs in liquidating the underlying
security. Repurchase agreements that mature in more than seven days
are subject to the 15% limit on illiquid investments. While it is not
possible to eliminate all risks from these transactions, it is the
policy of the Portfolios to limit repurchase agreements to those
parties whose creditworthiness has been reviewed and found
satisfactory by Janus Capital.

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<PAGE>

custodial account to cover its obligation under the agreement. The
Portfolios will enter into reverse repurchase agreements only with
parties that Janus Capital deems creditworthy. Using reverse
repurchase agreements to earn additional income involves the risk that
the interest earned on the invested proceeds is less than the expense
of the reverse repurchase agreement transaction. This technique may
also have a leveraging effect on the Portfolio, although the
Portfolio's intent to segregate assets in the amount of the reverse
repurchase agreement minimizes this effect.

High-Yield/High-Risk Bonds

The Portfolios intend to invest less than 35% of their respective net
assets in debt securities that are rated below investment grade (e.g.,
securities rated BB or lower by Standard & Poor's Ratings Services or
Ba or lower by Moody's Investors Service, Inc.). No other Portfolio
intends to invest 35% or more of its net assets in such securities.
Lower rated securities involve a higher degree of credit risk, which
is the risk that the issuer will not make interest or principal
payments when due. In the event of an unanticipated default, a
Portfolio would experience a reduction in its income, and could expect
a decline in the market value of the securities so affected.

Each Portfolio may also invest in unrated debt securities of foreign
and domestic issuers. Unrated debt, while not necessarily of lower
quality than rated securities, may not have as broad a market. Because
of the size and perceived demand of the issue, among other factors,
certain municipalities may not incur the costs of obtaining a rating.
A Portfolio's manager will analyze the creditworthiness of the issuer,
as well as any financial institution or other party responsible for
payments on the security, in determining whether to purchase unrated
municipal bonds. Unrated debt securities will be included in the 35%
limit of each Portfolio unless its manager deems such securities to be
the equivalent of investment grade securities.

Subject to the above limits, each Portfolio may purchase defaulted
securities only when its portfolio manager believes, based upon
analysis of the financial condition, results of operations and
economic outlook of an issuer, that there is potential for resumption
of income payments and that the securities offer an unusual
opportunity for capital appreciation. Notwithstanding the portfolio
manager's belief about the resumption of income, however, the purchase
of any security on which payment of interest or dividends is suspended
involves a high degree of risk. Such risk includes, among other
things, the following:

Financial and Market Risks. Investments in securities that are in
default involve a high degree of financial and market risks that can
result in substantial or, at times, even total losses. Issuers of
defaulted securities may have substantial capital needs and may become
involved in bankruptcy or reorganization proceedings. Among the
problems involved in investments in such issuers is the fact that it
may be difficult to obtain information about the condition of such
issuers. The market prices of such securities also are subject to
abrupt and erratic movements and above average price volatility, and
the spread between the bid and asked prices of such securities may be
greater than normally expected.

Disposition of Portfolio Securities. Although these Portfolios
generally will purchase securities for which their portfolio managers
expect an active market to be maintained, defaulted securities may be
less actively traded than other securities and it may be difficult to
dispose of substantial holdings of such securities at prevailing
market prices. The Portfolios will limit holdings of any such
securities to amounts that the portfolio managers believe could be
readily sold, and holdings of such securities would, in any event, be
limited so as not to limit the Portfolios' ability to readily dispose
of securities to meet redemptions.

Other. Defaulted securities require active monitoring and may, at
times, require participation in bankruptcy or receivership proceedings
on behalf of the Portfolios.

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Futures, Options and Other Derivative Instruments

FUTURES CONTRACTS. The Portfolios may enter into contracts for the
purchase or sale for future delivery of fixed-income securities,
foreign currencies or contracts based on financial indices, including
indices of U.S. government securities, foreign government securities,
equity or fixed-income securities. U.S. futures contracts are traded
on exchanges which have been designated "contract markets" by the CFTC
and must be executed through a futures commission merchant ("FCM"), or
brokerage firm, which is a member of the relevant contract market.
Through their clearing corporations, the exchanges guarantee
performance of the contracts as between the clearing members of the
exchange.

The buyer or seller of a futures contract is not required to deliver
or pay for the underlying instrument unless the contract is held until
the delivery date. However, both the buyer and seller are required to
deposit "initial margin" for the benefit of the FCM when the contract
is entered into. Initial margin deposits are equal to a percentage of
the contract's value, as set by the exchange on which the contract is
traded, and may be maintained in cash or certain other liquid assets
by the Portfolios' custodian or subcustodian for the benefit of the
FCM. Initial margin payments are similar to good faith deposits or
performance bonds. Unlike margin extended by a securities broker,
initial margin payments do not constitute purchasing securities on
margin for purposes of the Portfolio's investment limitations. If the
value of either party's position declines, that party will be required
to make additional "variation margin" payments for the benefit of the
FCM to settle the change in value on a daily basis. The party that has
a gain may be entitled to receive all or a portion of this amount. In
the event of the bankruptcy of the FCM that holds margin on behalf of
a Portfolio, that Portfolio may be entitled to return of margin owed
to such Portfolio only in proportion to the amount received by the
FCM's other customers. Janus Capital will attempt to minimize the risk
by careful monitoring of the creditworthiness of the FCMs with which
the Portfolios do business and by depositing margin payments in a
segregated account with the Portfolios' custodian.

The Portfolios intend to comply with guidelines of eligibility for
exclusion from the definition of the term "commodity pool operator"
adopted by the CFTC and the National Futures Association, which
regulate trading in the futures markets. The Portfolios will use
futures contracts and related options primarily for bona fide hedging
purposes within the meaning of CFTC regulations. To the extent that
the Portfolios hold positions in futures contracts and related options
that do not fall within the definition of bona fide hedging
transactions, the aggregate initial margin and premiums required to
establish such positions will not exceed 5% of the fair market value
of a Portfolio's net assets, after taking into account unrealized
profits and unrealized losses on any such contracts it has entered
into.

Although a Portfolio will segregate cash and liquid assets in an
amount sufficient to cover its open futures obligations, the
segregated assets would be available to that Portfolio immediately
upon closing out the futures position, while settlement of securities
transactions could take several days. However, because a Portfolio's
cash that may otherwise be invested would be held uninvested or
invested in other liquid assets so long as the futures position
remains open, such Portfolio's return could be diminished due to the
opportunity losses of foregoing other potential investments.

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<PAGE>

index as anticipated, the value of the futures contracts will
increase, thereby serving as a hedge against that Portfolio not
participating in a market advance. This technique is sometimes known
as an anticipatory hedge. To the extent a Portfolio enters into
futures contracts for this purpose, the segregated assets maintained
to cover such Portfolio's obligations with respect to the futures
contracts will consist of liquid assets from its portfolio in an
amount equal to the difference between the contract price and the
aggregate value of the initial and variation margin payments made by
that Portfolio with respect to the futures contracts. Conversely, if a
Portfolio holds stocks and seeks to protect itself from a decrease in
stock prices, the Portfolio might sell stock index futures contracts,
thereby hoping to offset the potential decline in the value of its
portfolio securities by a corresponding increase in the value of the
futures contract position. A Portfolio could protect against a decline
in stock prices by selling portfolio securities and investing in money
market instruments, but the use of futures contracts enables it to
maintain a defensive position without having to sell portfolio
securities.

If a Portfolio owns Treasury bonds and the portfolio manager expects
interest rates to increase, that Portfolio may take a short position
in interest rate futures contracts. Taking such a position would have
much the same effect as that Portfolio selling Treasury bonds in its
portfolio. If interest rates increase as anticipated, the value of the
Treasury bonds would decline, but the value of that Portfolio's
interest rate futures contract will increase, thereby keeping the net
asset value of that Portfolio from declining as much as it may have
otherwise. If, on the other hand, a portfolio manager expects interest
rates to decline, that Portfolio may take a long position in interest
rate futures contracts in anticipation of later closing out the
futures position and purchasing the bonds. Although a Portfolio can
accomplish similar results by buying securities with long maturities
and selling securities with short maturities, given the greater
liquidity of the futures market than the cash market, it may be
possible to accomplish the same result more easily and more quickly by
using futures contracts as an investment tool to reduce risk.

The ordinary spreads between prices in the cash and futures markets,
due to differences in the nature of those markets, are subject to
distortions. First, all participants in the futures market are subject
to initial margin and variation margin requirements. Rather than
meeting additional variation margin requirements, investors may close
out futures contracts through offsetting transactions which could
distort the normal price relationship between the cash and futures
markets. Second, the liquidity of the futures market depends on
participants entering into offsetting transactions rather than making
or taking delivery of the instrument underlying a futures contract. To
the extent participants decide to make or take delivery, liquidity in
the futures market could be reduced and prices in the futures market
distorted. Third, from the point of view of speculators, the margin
deposit requirements in the futures market are less onerous than
margin requirements in the securities market. Therefore, increased
participation by speculators in the futures market may cause temporary
price distortions. Due to the possibility of the foregoing
distortions, a correct forecast of general price trends by a portfolio
manager still may not result in a successful use of futures.

Futures contracts entail risks. Although the Portfolios believe that
use of such contracts will benefit the Portfolios, a Portfolio's
overall performance could be worse than if such Portfolio had not
entered into futures contracts if the portfolio manager's investment
judgement proves incorrect. For example, if a Portfolio has hedged
against the effects of a possible decrease in prices of securities
held in its portfolio and prices increase instead, that Portfolio will
lose part or all of the benefit of the increased value of these
securities because of offsetting losses in its futures positions. In
addition, if a Portfolio has insufficient cash, it may have to sell
securities from its portfolio to meet daily variation margin
requirements. Those sales may be, but will not necessarily be, at
increased prices which reflect the rising market and may occur at a
time when the sales are disadvantageous to such Portfolio.

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<PAGE>

The prices of futures contracts depend primarily on the value of their
underlying instruments. Because there are a limited number of types of
futures contracts, it is possible that the standardized futures
contracts available to a Portfolio will not match exactly such
Portfolio's current or potential investments. A Portfolio may buy and
sell futures contracts based on underlying instruments with different
characteristics from the securities in which it typically
invests - for example, by hedging investments in portfolio securities
with a futures contract based on a broad index of securities - which
involves a risk that the futures position will not correlate precisely
with the performance of such Portfolio's investments.

Futures prices can also diverge from the prices of their underlying
instruments, even if the underlying instruments closely correlate with
a Portfolio's investments. Futures prices are affected by factors such
as current and anticipated short-term interest rates, changes in
volatility of the underlying instruments and the time remaining until
expiration of the contract. Those factors may affect securities prices
differently from futures prices. Imperfect correlations between a
Portfolio's investments and its futures positions also may result from
differing levels of demand in the futures markets and the securities
markets, from structural differences in how futures and securities are
traded, and from imposition of daily price fluctuation limits for
futures contracts. A Portfolio may buy or sell futures contracts with
a greater or lesser value than the securities it wishes to hedge or is
considering purchasing in order to attempt to compensate for
differences in historical volatility between the futures contract and
the securities, although this may not be successful in all cases. If
price changes in a Portfolio's futures positions are poorly correlated
with its other investments, its futures positions may fail to produce
desired gains or result in losses that are not offset by the gains in
that Portfolio's other investments.

Because futures contracts are generally settled within a day from the
date they are closed out, compared with a settlement period of three
days for some types of securities, the futures markets can provide
superior liquidity to the securities markets. Nevertheless, there is
no assurance that a liquid secondary market will exist for any
particular futures contract at any particular time. In addition,
futures exchanges may establish daily price fluctuation limits for
futures contracts and may halt trading if a contract's price moves
upward or downward more than the limit in a given day. On volatile
trading days when the price fluctuation limit is reached, it may be
impossible for a Portfolio to enter into new positions or close out
existing positions. If the secondary market for a futures contract is
not liquid because of price fluctuation limits or otherwise, a
Portfolio may not be able to promptly liquidate unfavorable futures
positions and potentially could be required to continue to hold a
futures position until the delivery date, regardless of changes in its
value. As a result, such Portfolio's access to other assets held to
cover its futures positions also could be impaired.

OPTIONS ON FUTURES CONTRACTS. The Portfolios may buy and write put and
call options on futures contracts. An option on a future gives a
Portfolio the right (but not the obligation) to buy or sell a futures
contract at a specified price on or before a specified date. The
purchase of a call option on a futures contract is similar in some
respects to the purchase of a call option on an individual security.
Depending on the pricing of the option compared to either the price of
the futures contract upon which it is based or the price of the
underlying instrument, ownership of the option may or may not be less
risky than ownership of the futures contract or the underlying
instrument. As with the purchase of futures contracts, when a
Portfolio is not fully invested it may buy a call option on a futures
contract to hedge against a market advance.

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<PAGE>

amount of the option premium which provides a partial hedge against
any decline that may have occurred in that Portfolio's holdings. The
writing of a put option on a futures contract constitutes a partial
hedge against increasing prices of the security or foreign currency
which is deliverable under, or of the index comprising, the futures
contract. If the futures price at expiration of the option is higher
than the exercise price, a Portfolio will retain the full amount of
the option premium which provides a partial hedge against any increase
in the price of securities which that Portfolio is considering buying.
If a call or put option a Portfolio has written is exercised, such
Portfolio will incur a loss which will be reduced by the amount of the
premium it received. Depending on the degree of correlation between
the change in the value of its portfolio securities and changes in the
value of the futures positions, a Portfolio's losses from existing
options on futures may to some extent be reduced or increased by
changes in the value of portfolio securities.

The purchase of a put option on a futures contract is similar in some
respects to the purchase of protective put options on portfolio
securities. For example, a Portfolio may buy a put option on a futures
contract to hedge its portfolio against the risk of falling prices or
rising interest rates.

The amount of risk a Portfolio assumes when it buys an option on a
futures contract is the premium paid for the option plus related
transaction costs. In addition to the correlation risks discussed
above, the purchase of an option also entails the risk that changes in
the value of the underlying futures contract will not be fully
reflected in the value of the options bought.

FORWARD CONTRACTS. A forward contract is an agreement between two
parties in which one party is obligated to deliver a stated amount of
a stated asset at a specified time in the future and the other party
is obligated to pay a specified amount for the assets at the time of
delivery. The Portfolios may enter into forward contracts to purchase
and sell government securities, equity or income securities, foreign
currencies or other financial instruments. Forward contracts generally
are traded in an interbank market conducted directly between traders
(usually large commercial banks) and their customers. Unlike futures
contracts, which are standardized contracts, forward contracts can be
specifically drawn to meet the needs of the parties that enter into
them. The parties to a forward contract may agree to offset or
terminate the contract before its maturity, or may hold the contract
to maturity and complete the contemplated exchange.

The following discussion summarizes the Portfolios' principal uses of
forward foreign currency exchange contracts ("forward currency
contracts"). A Portfolio may enter into forward currency contracts
with stated contract values of up to the value of that Portfolio's
assets. A forward currency contract is an obligation to buy or sell an
amount of a specified currency for an agreed price (which may be in
U.S. dollars or a foreign currency). A Portfolio will exchange foreign
currencies for U.S. dollars and for other foreign currencies in the
normal course of business and may buy and sell currencies through
forward currency contracts in order to fix a price for securities it
has agreed to buy or sell ("transaction hedge"). A Portfolio also may
hedge some or all of its investments denominated in a foreign currency
or exposed to foreign currency fluctuations against a decline in the
value of that currency relative to the U.S. dollar by entering into
forward currency contracts to sell an amount of that currency (or a
proxy currency whose performance is expected to replicate or exceed
the performance of that currency relative to the U.S. dollar)
approximating the value of some or all of its portfolio securities
denominated in that currency ("position hedge") or by participating in
options or futures contracts with respect to the currency. A Portfolio
also may enter into a forward currency contract with respect to a
currency where the Portfolio is considering the purchase or sale of
investments denominated in that currency but has not yet selected the
specific investments ("anticipatory hedge"). In any of these
circumstances a Portfolio may, alternatively, enter into a forward
currency contract to purchase or sell one foreign currency for a
second currency that is expected

14
<PAGE>

to perform more favorably relative to the U.S. dollar if the portfolio
manager believes there is a reasonable degree of correlation between
movements in the two currencies ("cross-hedge").

These types of hedging minimize the effect of currency appreciation as
well as depreciation, but do not eliminate fluctuations in the
underlying U.S. dollar equivalent value of the proceeds of or rates of
return on a Portfolio's foreign currency denominated portfolio
securities. The matching of the increase in value of a forward
contract and the decline in the U.S. dollar equivalent value of the
foreign currency denominated asset that is the subject of the hedge
generally will not be precise. Shifting a Portfolio's currency
exposure from one foreign currency to another removes that Portfolio's
opportunity to profit from increases in the value of the original
currency and involves a risk of increased losses to such Portfolio if
its portfolio manager's projection of future exchange rates is
inaccurate. Proxy hedges and cross-hedges may result in losses if the
currency used to hedge does not perform similarly to the currency in
which hedged securities are denominated. Unforeseen changes in
currency prices may result in poorer overall performance for a
Portfolio than if it had not entered into such contracts.

The Portfolios will cover outstanding forward currency contracts by
maintaining liquid portfolio securities denominated in or whose value
is tied to the currency underlying the forward contract or the
currency being hedged. To the extent that a Portfolio is not able to
cover its forward currency positions with underlying portfolio
securities, the Portfolios' custodian will segregate cash or other
liquid assets having a value equal to the aggregate amount of such
Portfolio's commitments under forward contracts entered into with
respect to position hedges, cross-hedges and anticipatory hedges. If
the value of the securities used to cover a position or the value of
segregated assets declines, a Portfolio will find alternative cover or
segregate additional cash or other liquid assets on a daily basis so
that the value of the covered and segregated assets will be equal to
the amount of such Portfolio's commitments with respect to such
contracts. As an alternative to segregating assets, a Portfolio may
buy call options permitting such Portfolio to buy the amount of
foreign currency being hedged by a forward sale contract or a
Portfolio may buy put options permitting it to sell the amount of
foreign currency subject to a forward buy contract.

While forward contracts are not currently regulated by the CFTC, the
CFTC may in the future assert authority to regulate forward contracts.
In such event, the Portfolios' ability to utilize forward contracts
may be restricted. In addition, a Portfolio may not always be able to
enter into forward contracts at attractive prices and may be limited
in its ability to use these contracts to hedge Portfolio assets.

OPTIONS ON FOREIGN CURRENCIES. The Portfolios may buy and write
options on foreign currencies in a manner similar to that in which
futures or forward contracts on foreign currencies will be utilized.
For example, a decline in the U.S. dollar value of a foreign currency
in which portfolio securities are denominated will reduce the U.S.
dollar value of such securities, even if their value in the foreign
currency remains constant. In order to protect against such
diminutions in the value of portfolio securities, a Portfolio may buy
put options on the foreign currency. If the value of the currency
declines, such Portfolio will have the right to sell such currency for
a fixed amount in U.S. dollars, thereby offsetting, in whole or in
part, the adverse effect on its portfolio.

Conversely, when a rise in the U.S. dollar value of a currency in
which securities to be acquired are denominated is projected, thereby
increasing the cost of such securities, a Portfolio may buy call
options on the foreign currency. The purchase of such options could
offset, at least partially, the effects of the adverse movements in
exchange rates. As in the case of other types of options, however, the
benefit to a Portfolio from purchases of foreign currency options will
be reduced by the amount of the premium and related transaction costs.
In addition, if currency exchange rates do not move in the direction
or to the

15
<PAGE>

extent projected, a Portfolio could sustain losses on transactions in
foreign currency options that would require such Portfolio to forego a
portion or all of the benefits of advantageous changes in those rates.

The Portfolios may also write options on foreign currencies. For
example, to hedge against a potential decline in the U.S. dollar value
of foreign currency denominated securities due to adverse fluctuations
in exchange rates, a Portfolio could, instead of purchasing a put
option, write a call option on the relevant currency. If the expected
decline occurs, the option will most likely not be exercised and the
decline in value of portfolio securities will be offset by the amount
of the premium received.

Similarly, instead of purchasing a call option to hedge against a
potential increase in the U.S. dollar cost of securities to be
acquired, a Portfolio could write a put option on the relevant
currency which, if rates move in the manner projected, should expire
unexercised and allow that Portfolio to hedge the increased cost up to
the amount of the premium. As in the case of other types of options,
however, the writing of a foreign currency option will constitute only
a partial hedge up to the amount of the premium. If exchange rates do
not move in the expected direction, the option may be exercised and a
Portfolio would be required to buy or sell the underlying currency at
a loss which may not be offset by the amount of the premium. Through
the writing of options on foreign currencies, a Portfolio also may
lose all or a portion of the benefits which might otherwise have been
obtained from favorable movements in exchange rates.

The Portfolios may write covered call options on foreign currencies. A
call option written on a foreign currency by a Portfolio is "covered"
if that Portfolio owns the foreign currency underlying the call or has
an absolute and immediate right to acquire that foreign currency
without additional cash consideration (or for additional cash
consideration held in a segregated account by its custodian) upon
conversion or exchange of other foreign currencies held in its
portfolio. A call option is also covered if a Portfolio has a call on
the same foreign currency in the same principal amount as the call
written if the exercise price of the call held (i) is equal to or less
than the exercise price of the call written or (ii) is greater than
the exercise price of the call written, if the difference is
maintained by such Portfolio in cash or other liquid assets in a
segregated account with the Portfolios' custodian.

The Portfolios also may write call options on foreign currencies for
cross-hedging purposes. A call option on a foreign currency is for
cross-hedging purposes if it is designed to provide a hedge against a
decline due to an adverse change in the exchange rate in the U.S.
dollar value of a security which a Portfolio owns or has the right to
acquire and which is denominated in the currency underlying the
option. Call options on foreign currencies which are entered into for
cross-hedging purposes are not covered. However, in such
circumstances, a Portfolio will collateralize the option by
segregating cash or other liquid assets in an amount not less than the
value of the underlying foreign currency in U.S. dollars
marked-to-market daily.

OPTIONS ON SECURITIES. In an effort to increase current income and to
reduce fluctuations in net asset value, the Portfolios may write
covered put and call options and buy put and call options on
securities that are traded on United States and foreign securities
exchanges and over-the-counter. The Portfolios may write and buy
options on the same types of securities that the Portfolios may
purchase directly.

A put option written by a Portfolio is "covered" if that Portfolio (i)
segregates cash not available for investment or other liquid assets
with a value equal to the exercise price of the put with the
Portfolios' custodian or (ii) holds a put on the same security and in
the same principal amount as the put written and the exercise price of
the put held is equal to or greater than the exercise price of the put
written. The premium paid by the buyer of an option will reflect,
among other things, the relationship of the exercise price to the
market price and the volatility of the underlying security, the
remaining term of the option, supply and demand and interest rates.

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<PAGE>

A call option written by a Portfolio is "covered" if that Portfolio
owns the underlying security covered by the call or has an absolute
and immediate right to acquire that security without additional cash
consideration (or for additional cash consideration held in a
segregated account by the Portfolios' custodian) upon conversion or
exchange of other securities held in its portfolio. A call option is
also deemed to be covered if a Portfolio holds a call on the same
security and in the same principal amount as the call written and the
exercise price of the call held (i) is equal to or less than the
exercise price of the call written or (ii) is greater than the
exercise price of the call written if the difference is maintained by
that Portfolio in cash and other liquid assets in a segregated account
with its custodian.

The Portfolios also may write call options that are not covered for
cross-hedging purposes. A Portfolio collateralizes its obligation
under a written call option for cross-hedging purposes by segregating
cash or other liquid assets in an amount not less than the market
value of the underlying security, marked-to-market daily. A Portfolio
would write a call option for cross-hedging purposes, instead of
writing a covered call option, when the premium to be received from
the cross-hedge transaction would exceed that which would be received
from writing a covered call option and its portfolio manager believes
that writing the option would achieve the desired hedge.

The writer of an option may have no control over when the underlying
securities must be sold, in the case of a call option, or bought, in
the case of a put option, since with regard to certain options, the
writer may be assigned an exercise notice at any time prior to the
termination of the obligation. Whether or not an option expires
unexercised, the writer retains the amount of the premium. This
amount, of course, may, in the case of a covered call option, be
offset by a decline in the market value of the underlying security
during the option period. If a call option is exercised, the writer
experiences a profit or loss from the sale of the underlying security.
If a put option is exercised, the writer must fulfill the obligation
to buy the underlying security at the exercise price, which will
usually exceed the then market value of the underlying security.

The writer of an option that wishes to terminate its obligation may
effect a "closing purchase transaction." This is accomplished by
buying an option of the same series as the option previously written.
The effect of the purchase is that the writer's position will be
canceled by the clearing corporation. However, a writer may not effect
a closing purchase transaction after being notified of the exercise of
an option. Likewise, an investor who is the holder of an option may
liquidate its position by effecting a "closing sale transaction." This
is accomplished by selling an option of the same series as the option
previously bought. There is no guarantee that either a closing
purchase or a closing sale transaction can be effected.

In the case of a written call option, effecting a closing transaction
will permit a Portfolio to write another call option on the underlying
security with either a different exercise price or expiration date or
both. In the case of a written put option, such transaction will
permit a Portfolio to write another put option to the extent that the
exercise price is secured by deposited liquid assets. Effecting a
closing transaction also will permit a Portfolio to use the cash or
proceeds from the concurrent sale of any securities subject to the
option for other investments. If a Portfolio desires to sell a
particular security from its portfolio on which it has written a call
option, such Portfolio will effect a closing transaction prior to or
concurrent with the sale of the security.

17
<PAGE>

received from a sale transaction is less than the premium paid to buy
the option. Because increases in the market of a call option generally
will reflect increases in the market price of the underlying security,
any loss resulting from the repurchase of a call option is likely to
be offset in whole or in part by appreciation of the underlying
security owned by a Portfolio.

An option position may be closed out only where a secondary market for
an option of the same series exists. If a secondary market does not
exist, the Portfolio may not be able to effect closing transactions in
particular options and the Portfolio would have to exercise the
options in order to realize any profit. If a Portfolio is unable to
effect a closing purchase transaction in a secondary market, it will
not be able to sell the underlying security until the option expires
or it delivers the underlying security upon exercise. The absence of a
liquid secondary market may be due to the following: (i) insufficient
trading interest in certain options, (ii) restrictions imposed by a
national securities exchange ("Exchange") on which the option is
traded on opening or closing transactions or both, (iii) trading
halts, suspensions or other restrictions imposed with respect to
particular classes or series of options or underlying securities, (iv)
unusual or unforeseen circumstances that interrupt normal operations
on an Exchange, (v) the facilities of an Exchange or of the Options
Clearing Corporation ("OCC") may not at all times be adequate to
handle current trading volume, or (vi) one or more Exchanges could,
for economic or other reasons, decide or be compelled at some future
date to discontinue the trading of options (or a particular class or
series of options), in which event the secondary market on that
Exchange (or in that class or series of options) would cease to exist,
although outstanding options on that Exchange that had been issued by
the OCC as a result of trades on that Exchange would continue to be
exercisable in accordance with their terms.

A Portfolio may write options in connection with buy-and-write
transactions. In other words, a Portfolio may buy a security and then
write a call option against that security. The exercise price of such
call will depend upon the expected price movement of the underlying
security. The exercise price of a call option may be below
("in-the-money"), equal to ("at-the-money") or above
("out-of-the-money") the current value of the underlying security at
the time the option is written. Buy-and-write transactions using
in-the-money call options may be used when it is expected that the
price of the underlying security will remain flat or decline
moderately during the option period. Buy-and-write transactions using
at-the-money call options may be used when it is expected that the
price of the underlying security will remain fixed or advance
moderately during the option period. Buy-and-write transactions using
out-of-the-money call options may be used when it is expected that the
premiums received from writing the call option plus the appreciation
in the market price of the underlying security up to the exercise
price will be greater than the appreciation in the price of the
underlying security alone. If the call options are exercised in such
transactions, a Portfolio's maximum gain will be the premium received
by it for writing the option, adjusted upwards or downwards by the
difference between that Portfolio's purchase price of the security and
the exercise price. If the options are not exercised and the price of
the underlying security declines, the amount of such decline will be
offset by the amount of premium received.

The writing of covered put options is similar in terms of risk and
return characteristics to buy-and-write transactions. If the market
price of the underlying security rises or otherwise is above the
exercise price, the put option will expire worthless and a Portfolio's
gain will be limited to the premium received. If the market price of
the underlying security declines or otherwise is below the exercise
price, a Portfolio may elect to close the position or take delivery of
the security at the exercise price and that Portfolio's return will be
the premium received from the put options minus the amount by which
the market price of the security is below the exercise price.

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<PAGE>

A Portfolio may buy put options to hedge against a decline in the
value of its portfolio. By using put options in this way, a Portfolio
will reduce any profit it might otherwise have realized in the
underlying security by the amount of the premium paid for the put
option and by transaction costs.

A Portfolio may buy call options to hedge against an increase in the
price of securities that it may buy in the future. The premium paid
for the call option plus any transaction costs will reduce the
benefit, if any, realized by such Portfolio upon exercise of the
option, and, unless the price of the underlying security rises
sufficiently, the option may expire worthless to that Portfolio.

EURODOLLAR INSTRUMENTS. A Portfolio may make investments in Eurodollar
instruments. Eurodollar instruments are U.S. dollar-denominated
futures contracts or options thereon which are linked to the London
Interbank Offered Rate ("LIBOR"), although foreign
currency-denominated instruments are available from time to time.
Eurodollar futures contracts enable purchasers to obtain a fixed rate
for the lending of funds and sellers to obtain a fixed rate for
borrowings. A Portfolio might use Eurodollar futures contracts and
options thereon to hedge against changes in LIBOR, to which many
interest rate swaps and fixed-income instruments are linked.

SWAPS AND SWAP-RELATED PRODUCTS. A Portfolio may enter into interest
rate swaps, caps and floors on either an asset-based or
liability-based basis, depending upon whether it is hedging its assets
or its liabilities, and will usually enter into interest rate swaps on
a net basis (i.e., the two payment streams are netted out, with a
Portfolio receiving or paying, as the case may be, only the net amount
of the two payments). The net amount of the excess, if any, of a
Portfolio's obligations over its entitlement with respect to each
interest rate swap will be calculated on a daily basis and an amount
of cash or other liquid assets having an aggregate net asset value at
least equal to the accrued excess will be maintained in a segregated
account by the Portfolios' custodian. If a Portfolio enters into an
interest rate swap on other than a net basis, it would maintain a
segregated account in the full amount accrued on a daily basis of its
obligations with respect to the swap. A Portfolio will not enter into
any interest rate swap, cap or floor transaction unless the unsecured
senior debt or the claims-paying ability of the other party thereto is
rated in one of the three highest rating categories of at least one
NRSRO at the time of entering into such transaction. Janus Capital
will monitor the creditworthiness of all counterparties on an ongoing
basis. If there is a default by the other party to such a transaction,
a Portfolio will have contractual remedies pursuant to the agreements
related to the transaction.

The swap market has grown substantially in recent years with a large
number of banks and investment banking firms acting both as principals
and as agents utilizing standardized swap documentation. Janus Capital
has determined that, as a result, the swap market has become
relatively liquid. Caps and floors are more recent innovations for
which standardized documentation has not yet been developed and,
accordingly, they are less liquid than swaps. To the extent a
Portfolio sells (i.e., writes) caps and floors, it will segregate cash
or other liquid assets having an aggregate net asset value at least
equal to the full amount, accrued on a daily basis, of its obligations
with respect to any caps or floors.

There is no limit on the amount of interest rate swap transactions
that may be entered into by a Portfolio. These transactions may in
some instances involve the delivery of securities or other underlying
assets by a Portfolio or its counterparty to collateralize obligations
under the swap. Under the documentation currently used in those
markets, the risk of loss with respect to interest rate swaps is
limited to the net amount of the payments that a Portfolio is
contractually obligated to make. If the other party to an interest
rate swap that is not collateralized defaults, a Portfolio would risk
the loss of the net amount of the payments that it

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<PAGE>

contractually is entitled to receive. A Portfolio may buy and sell
(i.e., write) caps and floors without limitation, subject to the
segregation requirement described above.

ADDITIONAL RISKS OF OPTIONS ON FOREIGN CURRENCIES, FORWARD CONTRACTS
AND FOREIGN INSTRUMENTS. Unlike transactions entered into by the
Portfolios in futures contracts, options on foreign currencies and
forward contracts are not traded on contract markets regulated by the
CFTC or (with the exception of certain foreign currency options) by
the SEC. To the contrary, such instruments are traded through
financial institutions acting as market-makers, although foreign
currency options are also traded on certain Exchanges, such as the
Philadelphia Stock Exchange and the Chicago Board Options Exchange,
subject to SEC regulation. Similarly, options on currencies may be
traded over-the-counter. In an over-the-counter trading environment,
many of the protections afforded to Exchange participants will not be
available. For example, there are no daily price fluctuation limits,
and adverse market movements could therefore continue to an unlimited
extent over a period of time. Although the buyer of an option cannot
lose more than the amount of the premium plus related transaction
costs, this entire amount could be lost. Moreover, an option writer
and a buyer or seller of futures or forward contracts could lose
amounts substantially in excess of any premium received or initial
margin or collateral posted due to the potential additional margin and
collateral requirements associated with such positions.

Options on foreign currencies traded on Exchanges are within the
jurisdiction of the SEC, as are other securities traded on Exchanges.
As a result, many of the protections provided to traders on organized
Exchanges will be available with respect to such transactions. In
particular, all foreign currency option positions entered into on an
Exchange are cleared and guaranteed by the OCC, thereby reducing the
risk of counterparty default. Further, a liquid secondary market in
options traded on an Exchange may be more readily available than in
the over-the-counter market, potentially permitting a Portfolio to
liquidate open positions at a profit prior to exercise or expiration,
or to limit losses in the event of adverse market movements.

The purchase and sale of exchange-traded foreign currency options,
however, is subject to the risks of the availability of a liquid
secondary market described above, as well as the risks regarding
adverse market movements, margining of options written, the nature of
the foreign currency market, possible intervention by governmental
authorities and the effects of other political and economic events. In
addition, exchange-traded options on foreign currencies involve
certain risks not presented by the over-the-counter market. For
example, exercise and settlement of such options must be made
exclusively through the OCC, which has established banking
relationships in applicable foreign countries for this purpose. As a
result, the OCC may, if it determines that foreign governmental
restrictions or taxes would prevent the orderly settlement of foreign
currency option exercises, or would result in undue burdens on the OCC
or its clearing member, impose special procedures on exercise and
settlement, such as technical changes in the mechanics of delivery of
currency, the fixing of dollar settlement prices or prohibitions on
exercise.

In addition, options on U.S. government securities, futures contracts,
options on futures contracts, forward contracts and options on foreign
currencies may be traded on foreign exchanges and over-the-counter in
foreign countries. Such transactions are subject to the risk of
governmental actions affecting trading in or the prices of foreign
currencies or securities. The value of such positions also could be
adversely affected by (i) other complex foreign political and economic
factors, (ii) lesser availability than in the United States of data on
which to make trading decisions, (iii) delays in a Portfolio's ability
to act upon economic events occurring in foreign markets during
non-business hours in the United States, (iv) the imposition of
different exercise and settlement terms and procedures and margin
requirements than in the United States, and (v) low trading volume.

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Investment adviser

As stated in the Prospectus, each Portfolio has an Investment Advisory
Agreement with Janus Capital, 100 Fillmore Street, Denver, Colorado
80206-4928. Each Advisory Agreement provides that Janus Capital will
furnish continuous advice and recommendations concerning the
Portfolios' investments, provide office space for the Portfolios, and
pay the salaries, fees and expenses of all Portfolio officers and of
those Trustees who are affiliated with Janus Capital. Janus Capital
also may make payments to selected broker-dealer firms or institutions
which were instrumental in the acquisition of shareholders for the
Portfolios or other Janus Funds or which perform recordkeeping or
other services with respect to shareholder accounts. The minimum
aggregate size required for eligibility for such payments, and the
factors in selecting the broker-dealer firms and institutions to which
they will be made, are determined from time to time by Janus Capital.
Janus Capital is also authorized to perform the management and
administrative services necessary for the operation of the Portfolios.

The Portfolios pay custodian and transfer agent fees and expenses,
brokerage commissions and dealer spreads and other expenses in
connection with the execution of portfolio transactions, legal and
accounting expenses, interest and taxes, registration fees, expenses
of shareholders' meetings and reports to shareholders, fees and
expenses of Portfolio Trustees who are not affiliated with Janus
Capital and other costs of complying with applicable laws regulating
the sale of Portfolio shares. Pursuant to the Advisory Agreements,
Janus Capital furnishes certain other services, including net asset
value determination, portfolio accounting and recordkeeping, for which
the Portfolios may reimburse Janus Capital for its costs.

Global Life Sciences Portfolio and Global Technology Portfolio have
each agreed to compensate Janus Capital for its services by the
monthly payment of a fee at the annual rate of 0.75% of the first $300
million of the average daily net assets of each Portfolio, 0.70% of
the next $200 million of the average daily net assets of each
Portfolio and 0.65% on the average daily net assets of each Portfolio
in excess of $500 million. The advisory fee is calculated and payable
daily. Janus Capital has voluntarily agreed to cap the advisory fee of
Global Life Sciences Portfolio and Global Technology Portfolio at the
effective rate of Janus Global Life Sciences Fund and Janus Global
Technology Fund (the "retail funds"), respectively. The effective rate
of each retail fund is the advisory fee calculated by such fund on the
last day of each calendar quarter. If the assets of the corresponding
retail fund exceed the assets of a Portfolio as of the last day of any
calendar quarter, then the advisory fee payable by that Portfolio for
the following calendar quarter will be a flat rate equal to such
effective rate. The effective rate (annualized) of Janus Global Life
Sciences Fund and Janus Global Technology Fund were 0. % and 0. %,
respectively, for the quarter ended December 31, 1999. Janus Capital
has agreed to continue such reductions until at least the next annual
renewal of the advisory agreements.

In addition, Janus Capital has agreed to reimburse Global Life
Sciences Portfolio and Global Technology Portfolio by the amount, if
any, that such Portfolio's normal operating expenses in any fiscal
year, including the investment advisory fee but excluding brokerage
commissions, interest, taxes and extraordinary expenses, exceed an
annual rate of 1.25% of the average daily net assets of the Portfolio
until at least the next annual renewal of the advisory agreements.
Mortality risk, expense risk and other charges imposed by
participating insurance companies are excluded from the above expense
limitation.

The Advisory Agreement for each of the Portfolios is dated December
14, 1999 and will continue in effect from year to year so long as such
continuance is approved annually by a majority of the Portfolios'
Trustees who are not parties to the Advisory Agreements or interested
persons of any such party, and by either a majority of the outstanding
voting shares or the Trustees of the Portfolios. Each Advisory
Agreement (i) may be terminated without the payment of any penalty by
any Portfolio or Janus Capital on 60 days' written notice; (ii)
terminates automatically in the event of its assignment; and (iii)
generally, may not be amended without the approval by vote of a
majority of the Trustees of the affected Portfolio,

21
<PAGE>
including the Trustees who are not interested persons of that
Portfolio or Janus Capital and, to the extent required by the 1940
Act, the vote of a majority of the outstanding voting securities of
that Portfolio.

Janus Capital acts as sub-adviser for a number of private-label mutual
funds and provides separate account advisor services for institutional
accounts. Investment decisions for each account managed by Janus
Capital, including the Portfolios, are made independently from those
for any other account that is or may in the future become managed by
Janus Capital or its affiliates. If, however, a number of accounts
managed by Janus Capital are contemporaneously engaged in the purchase
or sale of the same security, the orders may be aggregated and/or the
transactions may be averaged as to price and allocated equitably to
each account. In some cases, this policy might adversely affect the
price paid or received by an account or the size of the position
obtained or liquidated for an account. Pursuant to an exemptive order
granted by the SEC, the Portfolios and other portfolios advised by
Janus Capital may also transfer daily uninvested cash balances into
one or more joint trading accounts. Assets in the joint trading
accounts are invested in money market instruments and the proceeds are
allocated to the participating portfolios on a pro rata basis.

[TO BE REVISED] Kansas City Southern Industries, Inc. ("KCSI") owns
approximately 82% of the outstanding voting stock of Janus Capital,
most of which it acquired in 1984. KCSI is a publicly traded holding
company whose primary subsidiaries are engaged in transportation,
information processing and financial services. Thomas H. Bailey,
President and Chairman of the Board of Janus Capital, owns
approximately 12% of its voting stock and, by agreement with KCSI,
selects a majority of Janus Capital's Board.

KCSI has announced its intention to separate its transportation and
financial services businesses. KCSI is currently studying alternatives
for completion of the separation that meet its business objectives
without risking adverse tax consequences. KCSI expects completion of
the separation to be contemplated in 1999.

Each account managed by Janus Capital has its own investment objective
and policies and is managed accordingly by a particular portfolio
manager or team of portfolio managers. As a result, from time to time
two or more different managed accounts may pursue divergent investment
strategies with respect to investments or categories of investments.

Janus Capital does not permit the Portfolios' portfolio managers to
purchase and sell securities for their own accounts except under the
limited exceptions contained in Janus Capital's policy regarding
personal investing by directors/Trustees, officers and employees of
Janus Capital and the Trust. The policy requires investment personnel
and officers of Janus Capital, inside directors/Trustees of Janus
Capital and the Portfolios and other designated persons deemed to have
access to current trading information to pre-clear all transactions in
securities not otherwise exempt under the policy. Requests for trading
authority will be denied when, among other reasons, the proposed
personal transaction would be contrary to the provisions of the policy
or would be deemed to adversely affect any transaction then known to
be under consideration for or to have been effected on behalf of any
client account, including the Portfolios.

In addition to the pre-clearance requirement described above, the
policy subjects investment personnel, officers and directors/Trustees
of Janus Capital and the Trust to various trading restrictions and
reporting obligations. All reportable transactions are required to be
reviewed for compliance with Janus Capital's policy. Those persons
also may be required under certain circumstances to forfeit their
profits made from personal trading.

The provisions of the policy are administered by and subject to
exceptions authorized by Janus Capital.

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Custodian, transfer agent and certain affiliations

State Street Bank and Trust Company, P.O. Box 0351, Boston,
Massachusetts 02117-0351 is the custodian of the domestic securities
and cash of the Portfolios. State Street and the foreign subcustodians
it selects, have custody of the assets of the Portfolios held outside
the U.S. and cash incidental thereto. The custodians and subcustodians
hold the Portfolios' assets in safekeeping and collect and remit the
income thereon, subject to the instructions of each Portfolio.

Janus Service Corporation, P.O. Box 173375, Denver, Colorado
80217-3375, a wholly-owned subsidiary of Janus Capital, is the
Portfolios' transfer agent. In addition, Janus Service provides
certain other administrative, recordkeeping and shareholder relations
services to the Portfolios. Janus Service is not compensated for its
services related to the Shares, except for out-of-pocket costs.

The Portfolios pay DST Systems, Inc., a subsidiary of KCSI, license
fees at the rate of $3.06 per shareholder account for the growth and
combination portfolios and $3.98 per shareholder account for the
fixed-income portfolios for the use of DST's shareholder accounting
system. The Portfolios also pay DST $1.10 per closed shareholder
account. The Portfolios pay DST for the use of its portfolio and fund
accounting system a monthly base fee of $250 to $1,250 per month based
on the number of Janus funds using the system and an asset charge of
$1 per million dollars of net assets (not to exceed $500 per month).

The Trustees have authorized the Portfolios to use another affiliate
of DST as introducing broker for certain Portfolio transactions as a
means to reduce Portfolio expenses through credits against the charges
of DST and its affiliates with regard to commissions earned by such
affiliate. DST charges shown above are net of such credits. See
"Portfolio Transactions and Brokerage."

Janus Distributors, Inc., 100 Fillmore Street, Denver, Colorado
80206-4928, a wholly-owned subsidiary of Janus Capital, is a
distributor of the Portfolios. Janus Distributors is registered as a
broker-dealer under the Securities Exchange Act of 1934 and is a
member of the National Association of Securities Dealers, Inc.

23
<PAGE>
Portfolio transactions and brokerage

Decisions as to the assignment of portfolio business for the
Portfolios and negotiation of its commission rates are made by Janus
Capital whose policy is to obtain the "best execution" (prompt and
reliable execution at the most favorable security price) of all
portfolio transactions. The Portfolios may trade foreign securities in
foreign countries because the best available market for these
securities is often on foreign exchanges. In transactions on foreign
stock exchanges, brokers' commissions are frequently fixed and are
often higher than in the United States, where commissions are
negotiated.

In selecting brokers and dealers and in negotiating commissions, Janus
Capital considers a number of factors, including but not limited to:
Janus Capital's knowledge of currently available negotiated commission
rates or prices of securities currently available and other current
transaction costs; the nature of the security being traded; the size
and type of the transaction; the nature and character of the markets
for the security to be purchased or sold; the desired timing of the
trade; the activity existing and expected in the market for the
particular security; confidentiality; the quality of the execution,
clearance and settlement services; financial stability of the broker
or dealer; the existence of actual or apparent operational problems of
any broker or dealer; rebates of commissions by a broker to a
Portfolio or to a third party service provider to the Portfolio to pay
Portfolio expenses; and research products or services provided. In
recognition of the value of the foregoing factors, Janus Capital may
place portfolio transactions with a broker or dealer with whom it has
negotiated a commission that is in excess of the commission another
broker or dealer would have charged for effecting that transaction if
Janus Capital determines in good faith that such amount of commission
was reasonable in relation to the value of the brokerage and research
provided by such broker or dealer viewed in terms of either that
particular transaction or of the overall responsibilities of Janus
Capital. Research may include furnishing advice, either directly or
through publications or writings, as to the value of securities, the
advisability of purchasing or selling specific securities and the
availability of securities or purchasers or sellers of securities;
furnishing seminars, information, analyses and reports concerning
issuers, industries, securities, trading markets and methods,
legislative developments, changes in accounting practices, economic
factors and trends and portfolio strategy; access to research
analysts, corporate management personnel, industry experts, economists
and government officials; comparative performance evaluation and
technical measurement services and quotation services, and products
and other services (such as third party publications, reports and
analyses, and computer and electronic access, equipment, software,
information and accessories that deliver, process or otherwise utilize
information, including the research described above) that assist Janus
Capital in carrying out its responsibilities. Research received from
brokers or dealers is supplemental to Janus Capital's own research
efforts. Most brokers and dealers used by Janus Capital provide
research and other services described above.

Janus Capital may use research products and services in servicing
other accounts in addition to the Portfolios. If Janus Capital
determines that any research product or service has a mixed use, such
that it also serves functions that do not assist in the investment
decision-making process, Janus Capital may allocate the costs of such
service or product accordingly. Only that portion of the product or
service that Janus Capital determines will assist it in the investment
decision-making process may be paid for in brokerage commission
dollars. Such allocation may create a conflict of interest for Janus
Capital.

Janus Capital does not enter into agreements with any brokers
regarding the placement of securities transactions because of the
research services they provide. It does, however, have an internal
procedure for allocating transactions in a manner consistent with its
execution policy to brokers that it has identified as providing
superior executions and research, research-related products or
services which benefit its advisory clients, including the Portfolios.
Research products and services incidental to effecting securities
transactions furnished by brokers or dealers may be used in servicing
any or all of Janus Capital's clients

24
<PAGE>

and such research may not necessarily be used by Janus Capital in
connection with the accounts which paid commissions to the
broker-dealer providing such research products and services.

Janus Capital may consider sales of Portfolio Shares or shares of
other Janus funds by a broker-dealer or the recommendation of a
broker-dealer to its customers that they purchase Portfolio Shares as
a factor in the selection of broker-dealers to execute Portfolio
transactions. Janus Capital may also consider payments made by brokers
effecting transactions for a Portfolio (i) to the Portfolio or (ii) to
other persons on behalf of the Portfolio for services provided to the
Portfolio for which it would be obligated to pay. In placing Portfolio
business with such broker-dealers, Janus Capital will seek the best
execution of each transaction.

When the Portfolios purchase or sell a security in the
over-the-counter market, the transaction takes place directly with a
principal market-maker, without the use of a broker, except in those
circumstances where in the opinion of Janus Capital better prices and
executions will be achieved through the use of a broker.

The Portfolios' Trustees have authorized Janus Capital to place
transactions with DST Securities, Inc. ("DSTS"), a wholly-owned
broker-dealer subsidiary of DST. Janus Capital may do so if it
reasonably believes that the quality of the transaction and the
associated commission are fair and reasonable and if, overall, the
associated transaction costs, net of any credits described above under
"Custodian, Transfer Agent and Certain Affiliations," are lower than
those that would otherwise be incurred.

25
<PAGE>
Trustees and officers

The following are the names of the Trustees and officers of the Trust,
together with a brief description of their principal occupations
during the last five years.

TRUSTEES

Thomas H. Bailey, Age 62 - Trustee, Chairman and President*#
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------
Trustee, Chairman and President of Janus Investment Fund. Chairman,
Chief Executive Officer, Director and President of Janus Capital.
Director of Janus Distributors, Inc.

James P. Craig, III, Age 43 - Trustee*#
100 Fillmore Street

Denver, CO 80206-4928
- --------------------------------------------------------------------------------

Trustee of Janus Investment Fund. Chief Investment Officer, Director
of Research, Vice Chairman and Director of Janus Capital. Formerly
Executive Vice President and Portfolio Manager of Growth Portfolio and
Janus Fund (from inception and 1986, respectively, until December
1999). Formerly Executive Vice President and Co-Manager of Janus
Venture Fund (from inception to December 1999).

Gary O. Loo, Age 59 - Trustee#
102 N. Cascade, Suite 500

Colorado Springs, CO 80903
- --------------------------------------------------------------------------------
Trustee of Janus Investment Fund. President and Director of High
Valley Group, Inc., Colorado Springs, CO (investments).

Dennis B. Mullen, Age 56 - Trustee

7500 E. McCormick Parkway, #24
Scottsdale, AZ 85258
- --------------------------------------------------------------------------------
Trustee of Janus Investment Fund. Private Investor. Formerly
(1997-1998), Chief Financial Officer-Boston Market Concepts, Boston
Chicken, Inc., Golden, CO (restaurant chain); (1993-1997), President
and Chief Executive Officer of BC Northwest, L.P., a franchise of
Boston Chicken, Inc., Bellevue, WA (restaurant chain).

James T. Rothe, Age 56 - Trustee

102 South Tejon Street, Suite 1100
Colorado Springs, CO 80903
- --------------------------------------------------------------------------------
Trustee of Janus Investment Fund. Professor of Business, University of
Colorado, Colorado Springs, CO. Principal, Phillips-Smith Retail
Group, Colorado Springs, CO (a venture capital firm). Formerly (1986-
1994), Dean of the College of Business, University of Colorado,
Colorado Springs, CO.

- --------------------------------------------------------------------------------
*Interested person of the Trust and of Janus Capital.
#Member of the Trust's Executive Committee.

26
<PAGE>

William D. Stewart, Age 56 - Trustee#
5330 Sterling Drive

Boulder, CO 80302

- --------------------------------------------------------------------------------

Trustee of Janus Investment Fund. President of HPS Division of MKS
Instruments, Boulder, CO (manufacturer of vacuum fittings and valves).

Martin H. Waldinger, Age 61 - Trustee

4940 Sandshore Court

San Diego, CA 92130

- --------------------------------------------------------------------------------

Trustee of Janus Investment Fund. Private Consultant. Formerly
(1993-1996), Director of Run Technologies, Inc., a software
development firm, San Carlos, CA.

OFFICERS

C. Mike Lu, Age 30 - Executive Vice President*

100 Fillmore Street

Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Portfolio Manager of Janus Investment Fund. Formerly, research analyst
at Janus Capital (1991-1998).

Thomas R. Malley, Age 30 - Executive Vice President*

100 Fillmore Street

Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Portfolio Manager of Janus Investment Fund. Formerly, research analyst
at Janus Capital (1991-1998).

Thomas A. Early, Age 45 - Vice President and General Counsel*
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Vice President and General Counsel of Janus Investment Fund. Vice
President, General Counsel and Secretary of Janus Capital. Vice
President and General Counsel of Janus Service Corporation, Janus
Distributors, Inc. and Janus Capital International, Ltd. Director of
Janus World Funds Plc. Formerly (1997 to 1998), Executive Vice
President and General Counsel of Prudential Investments Fund
Management LLC, Newark, New Jersey. Formerly (1994 to 1997), Vice
President and General Counsel of Prudential Retirement Services,
Newark, New Jersey.

- --------------------------------------------------------------------------------

#Member of the Trust's Executive Committee.

*Interested person of the Trust and of Janus Capital.

27
<PAGE>

Steven R. Goodbarn, Age 42 - Vice President and Chief Financial Officer*
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------
Vice President and Chief Financial Officer of Janus Investment Fund+.
Vice President of Finance, Treasurer and Chief Financial Officer of
Janus Capital, Janus Service Corporation, and Janus Distributors, Inc.
Director of Janus Service Corporation, Janus Distributors, Inc. and
Janus World Funds Plc. Director, Treasurer and Vice President of
Finance of Janus Capital International Ltd. Formerly (1992-1996),
Treasurer of Janus Investment Fund and Janus Aspen Series.

Kelley Abbott Howes, Age 34 - Assistant Vice President and Secretary*
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Vice President and Secretary of Janus Investment Fund. Vice President
and Associate Counsel of Janus Capital. Vice President of Janus
Distributors, Inc. Assistant Vice President of Janus Service
Corporation.

Glenn P. O'Flaherty, Age 41 - Treasurer and Chief Accounting Officer*
100 Fillmore Street, Suite 300
Denver, CO 80206-4928

The Trustees are responsible for major decisions relating to each
Portfolio's objective, policies and techniques. The Trustees also
supervise the operation of the Portfolios by their officers and review
the investment decisions of the officers although they do not actively
participate on a regular basis in making such decisions.

The Trust's Executive Committee shall have and may exercise all the
powers and authority of the Trustees except for matters requiring
action by all Trustees pursuant to the Trust's Bylaws or Trust
Instrument, Delaware law or the 1940 Act.

- --------------------------------------------------------------------------------

*Interested person of the Trust and of Janus Capital.

28
<PAGE>

The following table shows the aggregate compensation paid to each
Trustee by the Portfolios described in this Statement of Additional
Information and all funds advised and sponsored by Janus Capital
(collectively, the "Janus Funds") for the periods indicated. None of
the Trustees receive pension or retirement benefits from the
Portfolios or the Janus Funds.

<TABLE>
<CAPTION>
Aggregate Compensation Total Compensation
from the Portfolios for from the Janus Funds for
fiscal year ended calendar year ended
Name of Person, Position December 31, 1999 December 31, 1999**
<S> <C> <C>
- -----------------------------------------------------------------------------------------------------------------
Thomas H. Bailey, Chairman and Trustee* $ 0 $
James P. Craig, III, Trustee* $ 0 $
William D. Stewart, Trustee $ 0 $
Gary O. Loo, Trustee $ 0 $
Dennis B. Mullen, Trustee $ 0 $
Martin H. Waldinger, Trustee $ 0 $
James T. Rothe, Trustee $ 0 $
</TABLE>

* An interested person of the Portfolios and of Janus Capital. Compensated by
Janus Capital and not the Portfolios.

** As of December 31, 1999, Janus Funds consisted of two registered investment
companies comprised of a total of 32 funds.

29
<PAGE>
Shares of the trust

NET ASSET VALUE DETERMINATION

As stated in the Prospectus, the net asset value ("NAV") of the Shares
of each Portfolio is determined once each day on which the NYSE is
open, at the close of its regular trading session (normally 4:00 p.m.,
New York time, Monday through Friday). The NAV of the Shares of each
Portfolio is not determined on days the NYSE is closed (generally, New
Year's Day, Martin Luther King Day, Presidents' Day, Good Friday,
Memorial Day, Independence Day, Labor Day, Thanksgiving and
Christmas). The per Share NAV of the Shares of each Portfolio is
determined by dividing the total value of a Portfolio's securities and
other assets, less liabilities, attributable to the Shares of a
Portfolio, by the total number of Shares outstanding. In determining
NAV, securities listed on an Exchange, the NASDAQ National Market and
foreign markets are valued at the closing prices on such markets, or
if such price is lacking for the trading period immediately preceding
the time of determination, such securities are valued at their current
bid price. Municipal securities held by the Portfolios are traded
primarily in the over-the-counter market. Valuations of such
securities are furnished by one or more pricing services employed by
the Portfolios and are based upon last trade or closing sales prices
or a computerized matrix system or appraisals obtained by a pricing
service, in each case in reliance upon information concerning market
transactions and quotations from recognized municipal securities
dealers. Other securities that are traded on the over-the-counter
market are valued at their closing bid prices. Foreign securities and
currencies are converted to U.S. dollars using the exchange rate in
effect at the close of the NYSE. Each Portfolio will determine the
market value of individual securities held by it, by using prices
provided by one or more professional pricing services which may
provide market prices to other funds, or, as needed, by obtaining
market quotations from independent broker-dealers. Short-term
securities maturing within 60 days are valued on an amortized cost
basis. Securities for which quotations are not readily available, and
other assets, are valued at fair values determined in good faith under
procedures established by and under the supervision of the Trustees.

Trading in securities on European and Far Eastern securities exchanges
and over-the-counter markets is normally completed well before the
close of business on each business day in New York (i.e., a day on
which the NYSE is open). In addition, European or Far Eastern
securities trading generally or in a particular country or countries
may not take place on all business days in New York. Furthermore,
trading takes place in Japanese markets on certain Saturdays and in
various foreign markets on days which are not business days in New
York and on which a Portfolio's NAV is not calculated. A Portfolio
calculates its NAV per Share, and therefore effects sales, redemptions
and repurchases of its Shares, as of the close of the NYSE once on
each day on which the NYSE is open. Such calculation may not take
place contemporaneously with the determination of the prices of the
foreign portfolio securities used in such calculation.

PURCHASES

Shares of the Portfolios can be purchased only by (i) the separate
accounts of participating insurance companies for the purpose of
funding variable insurance contracts and (ii) certain qualified
retirement plans. Participating insurance companies and certain other
designated organizations are authorized to receive purchase orders on
the Portfolios' behalf and those organizations are authorized to
designate their agents and affiliates as intermediaries to receive
purchase orders. Purchase orders are deemed received by a Portfolio
when authorized organizations, their agents or affiliates receive the
order. The Portfolios are not responsible for the failure of any
designated organization or its agents or affiliates to carry out its
obligations to its customers. Shares of the Portfolios are purchased
at the NAV per Share as determined at the close of the regular trading
session of the NYSE next occurring after a purchase order is received
and accepted by a Portfolio or its authorized agent. In order to
receive a day's price, your order must be received by the close of the
regular trading session of the NYSE as described above in "Net Asset
Value

30
<PAGE>

Determination." The prospectus for your insurance company's separate
account or your plan documents contain detailed information about
investing in the different Portfolios.

REDEMPTIONS

Redemptions, like purchases, may only be effected through the separate
accounts of participating insurance companies or qualified retirement
plans. Certain designated organizations are authorized to receive
redemption orders on the Portfolios' behalf and those organizations
are authorized to designate their agents and affiliates as
intermediaries to receive redemption orders. Redemption orders are
deemed received by a Portfolio when authorized organizations, their
agents or affiliates receive the order. The Portfolios are not
responsible for the failure of any designated organization or its
agents or affiliates to carry out its obligations to its customers.
Shares normally will be redeemed for cash, although each Portfolio
retains the right to redeem its Shares in kind under unusual
circumstances, in order to protect the interests of remaining
shareholders, by delivery of securities selected from its assets at
its discretion. However, the Portfolios are governed by Rule 18f-1
under the 1940 Act, which requires each Portfolio to redeem shares
solely in cash up to the lesser of $250,000 or 1% of the NAV of that
Portfolio during any 90-day period for any one shareholder. Should
redemptions by any shareholder exceed such limitation, a Portfolio
will have the option of redeeming the excess in cash or in kind. If
shares are redeemed in kind, the redeeming shareholder might incur
brokerage costs in converting the assets to cash. The method of
valuing securities used to make redemptions in kind will be the same
as the method of valuing portfolio securities described under "Shares
of the Trust - Net Asset Value Determination" and such valuation will
be made as of the same time the redemption price is determined.

The right to require the Portfolios to redeem their shares may be
suspended, or the date of payment may be postponed, whenever (1)
trading on the NYSE is restricted, as determined by the SEC, or the
NYSE is closed except for holidays and weekends, (2) the SEC permits
such suspension and so orders, or (3) an emergency exists as
determined by the SEC so that disposal of securities or determination
of NAV is not reasonably practicable.

31
<PAGE>
Income dividends, capital gains distributions and tax status

It is a policy of the Shares of the Portfolios to distribute
substantially all of their respective investment income at least
semi-annually and their respective net realized gains, if any at least
annually. The Portfolios intend to qualify as regulated investment
companies by satisfying certain requirements prescribed by Subchapter
M of the Internal Revenue Code ("Code"). In addition, each Portfolio
intends to comply with the diversification requirements of Code
Section 817(h) related to the tax-deferred status of insurance company
separate accounts.

All income dividends and capital gains distributions, if any, on a
Portfolio's Shares are reinvested automatically in additional Shares
of that Portfolio at the NAV determined on the first business day
following the record date.

The Portfolios may purchase securities of certain foreign corporations
considered to be passive foreign investment companies by the IRS. In
order to avoid taxes and interest that must be paid by the Portfolios
if these instruments appreciate in value, the Portfolios may make
various elections permitted by the tax laws. However, these elections
could require that the Portfolios recognize taxable income, which in
turn must be distributed, before the securities are sold and before
cash is received to pay the distributions.

Some foreign securities purchased by the Portfolios may be subject to
foreign taxes which could reduce the yield on such securities. The
amount of such foreign taxes is expected to be insignificant. The
Portfolios may from year to year make the election permitted under
Section 853 of the Code to pass through such taxes to shareholders. If
such election is not made, any foreign taxes paid or accrued will
represent an expense to each Portfolio which will reduce its
investment company taxable income.

Because Shares of the Portfolios can only be purchased through
variable insurance contracts or qualified plans, it is anticipated
that any income dividends or capital gains distributions will be
exempt from current taxation if left to accumulate within such
contracts or plans. See the prospectus for the separate account of the
related insurance company or the plan documents for additional
information.

32
<PAGE>
Miscellaneous information

Each Portfolio is a series of the Trust, an open-end management
investment company registered under the 1940 Act and organized as a
Delaware business trust on May 20, 1993. As of the date of this SAI,
the Trust is offering thirteen series of shares, known as
"Portfolios," each of which consists of three classes of shares except
for Global Life Sciences Portfolio and Global Technology Portfolio
which consist of two classes of shares. Additional series and/or
classes may be created from time to time.

SHARES OF THE TRUST

The Trust is authorized to issue an unlimited number of shares of
beneficial interest with a par value of $.001 per share for each
series of the Trust. Shares of each Portfolio are fully paid and
nonassessable when issued. Shares of a Portfolio participate equally
in dividends and other distributions by the shares of such Portfolio,
and in residual assets of that Portfolio in the event of liquidation.
Shares of each Portfolio have no preemptive, conversion or
subscription rights.

The Portfolios each offer two classes of shares. The Shares discussed
in this SAI are offered only in connection with investment in and
payments under variable insurance contracts and to qualified
retirement plans. A second class of shares, Service Shares, is offered
in connection with investment in and payments under variable insurance
contracts and to qualified retirement plans that require a fee from
Portfolio assets to procure distribution and administrative services
to contract owners and plan participants.

SHAREHOLDER MEETINGS

The Trust does not intend to hold annual shareholder meetings.
However, special meetings may be called for a specific Portfolio or
for the Trust as a whole for purposes such as electing or removing
Trustees, terminating or reorganizing the Trust, changing fundamental
policies, or for any other purpose requiring a shareholder vote under
the 1940 Act. Separate votes are taken by each Portfolio or class only
if a matter affects or requires the vote of only that Portfolio or
class or that Portfolio's or class' interest in the matter differs
from the interest of other Portfolios of the Trust. Shareholders are
entitled to one vote for each Share owned.

VOTING RIGHTS

A participating insurance company issuing a variable insurance
contract will vote shares in the separate account as required by law
and interpretations thereof, as may be amended or changed from time to
time. In accordance with current law and interpretations, a
participating insurance company is required to request voting
instructions from policy owners and must vote shares in the separate
account, including shares for which no instructions have been
received, in proportion to the voting instructions received.
Additional information may be found in the participating insurance
company's separate account prospectus.

The Trustees are responsible for major decisions relating to each
Portfolio's policies and objectives; the Trustees oversee the
operation of each Portfolio by its officers and review the investment
decisions of the officers.

The present Trustees were elected by the initial trustee of the Trust
on May 25, 1993, and were approved by the initial shareholder on May
25, 1993, with the exception of Mr. Craig and Mr. Rothe who were
appointed by the Trustees as of June 30, 1995 and as of January 1,
1997, respectively. Under the Trust Instrument, each Trustee will
continue in office until the termination of the Trust or his earlier
death, retirement, resignation, bankruptcy, incapacity or removal.
Vacancies will be filled by a majority of the remaining Trustees,
subject to the 1940 Act. Therefore, no annual or regular meetings of
shareholders normally will be held, unless otherwise required by the
Trust Instrument or the 1940 Act. Subject to the

33
<PAGE>

foregoing, shareholders have the power to vote to elect or remove
Trustees, to terminate or reorganize their Portfolio, to amend the
Trust Instrument, to bring certain derivative actions and on any other
matters on which a shareholder vote is required by the 1940 Act, the
Trust Instrument, the Trust's Bylaws or the Trustees.

As mentioned above in "Shareholder Meetings," each share of each
portfolio of the Trust has one vote (and fractional votes for
fractional shares). Shares of all portfolios of the Trust have
noncumulative voting rights, which means that the holders of more than
50% of the shares of all series of the Trust voting for the election
of Trustees can elect 100% of the Trustees if they choose to do so
and, in such event, the holders of the remaining shares will not be
able to elect any Trustees.

INDEPENDENT ACCOUNTANTS

PricewaterhouseCoopers LLP, 950 Seventeenth Street, Suite 2500,
Denver, Colorado 80202, independent accountants for the Portfolios,
audit the Portfolios' annual financial statements and prepare their
tax returns.

REGISTRATION STATEMENT

The Trust has filed with the SEC, Washington, D.C., a Registration
Statement under the Securities Act of 1933, as amended, with respect
to the securities to which this SAI relates. If further information is
desired with respect to the Portfolios or such securities, reference
is made to the Registration Statement and the exhibits filed as a part
thereof.

34
<PAGE>
Performance information

Quotations of average annual total return for the Shares of a
Portfolio will be expressed in terms of the average annual compounded
rate of return of a hypothetical investment in the Shares of such
Portfolio over periods of 1, 5, and 10 years (up to the life of the
Portfolio). These are the annual total rates of return that would
equate the initial amount invested to the ending redeemable value.
These rates of return are calculated pursuant to the following
formula: P(1 + T)(n) = ERV (where P = a hypothetical initial payment
of $1,000, T = the average annual total return, n = the number of
years and ERV = the ending redeemable value of a hypothetical $1,000
payment made at the beginning of the period). All total return figures
reflect the deduction of a proportional share of expenses of the
Shares of a Portfolio on an annual basis, and assume that all
dividends and distributions are reinvested when paid.

From time to time in advertisements or sales material, the Portfolios
may discuss their performance ratings or other information as
published by recognized mutual fund statistical rating services,
including, but not limited to, Lipper Analytical Services, Inc.,
Ibbotson Associates, Micropal or Morningstar, Inc. or by publications
of general interest such as Forbes, Money, The Wall Street Journal,
Mutual Funds Magazine, Kiplinger's or Smart Money. The Portfolios may
also compare their performance to that of other selected mutual funds
(for example, peer groups created by Lipper or Morningstar), mutual
fund averages or recognized stock market indicators, including, but
not limited to, the Standard & Poor's 500 Composite Stock Price Index,
the Dow Jones Industrial Average, and the NASDAQ composite. Global
Life Sciences and Global Technology Portfolios may also compare their
performance to the record of global market indicators, such as the
Morgan Stanley International World Index or Morgan Stanley Capital
International Europe, Australasia, Far East Index (EAFE Index). Such
performance ratings or comparisons may be made with funds that may
have different investment restrictions, objectives, policies or
techniques than the Portfolios and such other funds or market
indicators may be comprised of securities that differ significantly
from the Portfolios' investments.

35
<PAGE>
Appendix A

EXPLANATION OF RATING CATEGORIES

The following is a description of credit ratings issued by two of the
major credit ratings agencies. Credit ratings evaluate only the safety
of principal and interest payments, not the market value risk of lower
quality securities. Credit rating agencies may fail to change credit
ratings to reflect subsequent events on a timely basis. Although Janus
Capital considers security ratings when making investment decisions,
it also performs its own investment analysis and does not rely solely
on the ratings assigned by credit agencies.

STANDARD & POOR'S
RATINGS SERVICES

<TABLE>
<S> <C>
BOND RATING EXPLANATION
-----------------------------------------------------------------------------------------
Investment Grade
AAA......................... Highest rating; extremely strong capacity to pay principal
and interest.
AA.......................... High quality; very strong capacity to pay principal and
interest.
A........................... Strong capacity to pay principal and interest; somewhat more
susceptible to the adverse effects of changing circumstances
and economic conditions.
BBB......................... Adequate capacity to pay principal and interest; normally
exhibit adequate protection parameters, but adverse economic
conditions or changing circumstances more likely to lead to
a weakened capacity to pay principal and interest than for
higher rated bonds.
Non-Investment Grade
BB, B, CCC, CC, C........... Predominantly speculative with respect to the issuer's
capacity to meet required interest and principal payments.
BB -- lowest degree of speculation; C -- the highest degree
of speculation. Quality and protective characteristics
outweighed by large uncertainties or major risk exposure to
adverse conditions.
D........................... In default.
</TABLE>

MOODY'S INVESTORS SERVICE, INC.

<TABLE>
<S> <C>
BOND RATING EXPLANATION
-----------------------------------------------------------------------------------------
Investment Grade
Aaa......................... Highest quality, smallest degree of investment risk.
Aa.......................... High quality; together with Aaa bonds, they compose the
high-grade bond group.
A........................... Upper-medium grade obligations; many favorable investment
attributes.
Baa......................... Medium-grade obligations; neither highly protected nor
poorly secured. Interest and principal appear adequate for
the present but certain protective elements may be lacking
or may be unreliable over any great length of time.
Non-Investment Grade
Ba.......................... More uncertain, with speculative elements. Protection of
interest and principal payments not well safeguarded during
good and bad times.
B........................... Lack characteristics of desirable investment; potentially
low assurance of timely interest and principal payments or
maintenance of other contract terms over time.
Caa......................... Poor standing, may be in default; elements of danger with
respect to principal or interest payments.
Ca.......................... Speculative in a high degree; could be in default or have
other marked shortcomings.
C........................... Lowest-rated; extremely poor prospects of ever attaining
investment standing.
</TABLE>

Unrated securities will be treated as noninvestment grade securities
unless the portfolio manager determines that such securities are the
equivalent of investment grade securities. Securities that have
received ratings from more than one agency are considered investment
grade if at least one agency has rated the security investment grade.

36
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<PAGE>

LOGO

1-800-525-0020

100 Fillmore Street

Denver, Colorado 80206-4928

janus.com

SCAI0599

<PAGE>

LOGO

Subject to Completion

Preliminary Statement of Additional Information Dated
November 1, 1999

Janus Aspen Series

Service Shares

Global Life Sciences Portfolio

Global Technology Portfolio

100 Fillmore Street
Denver, CO 80206-4928

(800) 525-0020

Statement of Additional Information

January 15, 2000

This Statement of Additional Information expands upon and
supplements the information contained in the current Prospectus
for the Retirement Shares (the "Shares") of the portfolios
listed above, each of which is a separate series of Janus Aspen
Series, a Delaware business trust. Each of these series of the
Trust represents shares of beneficial interest in a separate
portfolio of securities and other assets with its own objective
and policies. Each Portfolio is managed separately by Janus
Capital Corporation.

The Service Shares of the Portfolios may be purchased only by
separate accounts of insurance companies for the purpose of
funding variable life insurance policies and variable annuity
contracts (collectively, "variable insurance contracts") and by
certain qualified retirement plans.

This SAI is not a Prospectus and should be read in conjunction
with the Portfolios' Prospectus dated January 15, 2000, which
is incorporated by reference into this SAI and may be obtained
from your insurance company or plan sponsor. This SAI contains
additional and more detailed information about the Portfolios'
operations and activities than the Prospectus. The Annual
Reports, which contain important financial information about
the Portfolios, are incorporated by reference into this SAI and
are also available, without charge from your insurance company
or plan sponsor.

<PAGE>

LOGO
<PAGE>
Table of contents

<TABLE>
<S> <C>
Classification, Portfolio Turnover, Investment Policies and
Restrictions, and Investment Strategies and Risks........... 2
Investment Adviser.......................................... 21
Custodian, Transfer Agent and Certain Affiliations.......... 23
Portfolio Transactions and Brokerage........................ 24
Trustees and Officers....................................... 26
Shares of the Trust......................................... 30
Net Asset Value Determination............................ 30
Purchases................................................ 30
Distribution and Shareholder Servicing Plan.............. 31
Redemptions.............................................. 31
Income Dividends, Capital Gains Distributions and Tax
Status...................................................... 33
Miscellaneous Information................................... 34
Shares of the Trust...................................... 34
Shareholder Meetings..................................... 34
Voting Rights............................................ 34
Independent Accountants.................................. 35
Registration Statement................................... 35
Performance Information..................................... 36
Appendix A.................................................. 37
Explanation of Rating Categories......................... 37
</TABLE>

1
<PAGE>
Classification, portfolio turnover, investment policies
and restrictions, and investment
strategies and risks

CLASSIFICATION

PORTFOLIO TURNOVER

INVESTMENT POLICIES AND RESTRICTIONS

(2) Invest directly in real estate or interests in real estate;
however, the Portfolios may own debt or equity securities issued by
companies engaged in those businesses.

(5) Act as an underwriter of securities issued by others, except to
the extent that a Portfolio may be deemed an underwriter in connection
with the disposition of its portfolio securities.

2
<PAGE>

investment company with substantially the same fundamental investment
objective, policies and limitations as such Portfolio.

(g) The Portfolios may not invest in companies for the purpose of
exercising control of management.

3
<PAGE>

INVESTMENT STRATEGIES AND RISKS

Cash Position

Illiquid Investments

4
<PAGE>

Securities Lending

Short Sales

Zero Coupon, Step Coupon and Pay-In-Kind Securities

Each Portfolio may invest up to 10% (without limit for High-Yield
Portfolio and Flexible Income Portfolio) of its assets in zero coupon,
pay-in-kind and step coupon securities. Zero coupon bonds are issued
and traded at a discount from their face value. They do not entitle
the holder to any periodic payment of interest prior to maturity. Step
coupon bonds trade at a discount from their face value and pay coupon
interest. The coupon rate is low for an initial period and then
increases to a higher coupon rate thereafter. The discount from the
face amount or par value depends on the time remaining until cash
payments begin, prevailing interest rates, liquidity of the security
and the perceived credit quality of the issuer. Pay-in-kind bonds
normally give the issuer an option to pay cash at a coupon payment
date or give the holder of the security a similar bond with the same
coupon rate and a face value equal to the amount of the coupon payment
that would have been made. For the purposes of any Portfolio's
restriction on investing in income-producing securities,
income-producing securities include securities that make periodic
interest payments as well as those that make interest payments on a
deferred basis or pay interest only at maturity (e.g., Treasury bills
or zero coupon bonds).

5
<PAGE>

have to distribute cash obtained from other sources in order to
satisfy the distribution requirements under the Code. A Portfolio
might obtain such cash from selling other portfolio holdings which
might cause that Portfolio to incur capital gains or losses on the
sale. Additionally, these actions are likely to reduce the assets to
which Portfolio expenses could be allocated and to reduce the rate of
return for that Portfolio. In some circumstances, such sales might be
necessary in order to satisfy cash distribution requirements even
though investment considerations might otherwise make it undesirable
for a Portfolio to sell the securities at the time.

Pass-Through Securities

The Portfolios may invest in various types of pass-through securities,
such as mortgage-backed securities, asset-backed securities and
participation interests. A pass-through security is a share or
certificate of interest in a pool of debt obligations that have been
repackaged by an intermediary, such as a bank or broker-dealer. The
purchaser of a pass-through security receives an undivided interest in
the underlying pool of securities. The issuers of the underlying
securities make interest and principal payments to the intermediary
which are passed through to purchasers, such as the Portfolios. The
most common type of pass-through securities are mortgage-backed
securities. Government National Mortgage Association ("GNMA")
Certificates are mortgage-backed securities that evidence an undivided
interest in a pool of mortgage loans. GNMA Certificates differ from
bonds in that principal is paid back monthly by the borrowers over the
term of the loan rather than returned in a lump sum at maturity. A
Portfolio will generally purchase "modified pass-through" GNMA
Certificates, which entitle the holder to receive a share of all
interest and principal payments paid and owned on the mortgage pool,
net of fees paid to the "issuer" and GNMA, regardless of whether or
not the mortgagor actually makes the payment. GNMA Certificates are
backed as to the timely payment of principal and interest by the full
faith and credit of the U.S. government.

6
<PAGE>

loans are for specified periods of time, such as 20 or 30 years, the
borrowers can, and typically do, pay them off sooner. Thus, the
security holders frequently receive prepayments of principal in
addition to the principal that is part of the regular monthly
payments. A portfolio manager will consider estimated prepayment rates
in calculating the average-weighted maturity of a Portfolio. A
borrower is more likely to prepay a mortgage that bears a relatively
high rate of interest. This means that in times of declining interest
rates, higher yielding mortgage-backed securities held by a Portfolio
might be converted to cash and that Portfolio will be forced to accept
lower interest rates when that cash is used to purchase additional
securities in the mortgage-backed securities sector or in other
investment sectors. Additionally, prepayments during such periods will
limit a Portfolio's ability to participate in as large a market gain
as may be experienced with a comparable security not subject to
prepayment.

Asset-backed securities represent interests in pools of consumer loans
and are backed by paper or accounts receivables originated by banks,
credit card companies or other providers of credit. Generally, the
originating bank or credit provider is neither the obligor nor the
guarantor of the security, and interest and principal payments
ultimately depend upon payment of the underlying loans by individuals.
Tax-exempt asset-backed securities include units of beneficial
interests in pools of purchase contracts, financing leases, and sales
agreements that may be created when a municipality enters into an
installment purchase contract or lease with a vendor. Such securities
may be secured by the assets purchased or leased by the municipality;
however, if the municipality stops making payments, there generally
will be no recourse against the vendor. The market for tax-exempt
asset-backed securities is still relatively new. These obligations are
likely to involve unscheduled prepayments of principal.

Investment Company Securities

Depositary Receipts

7
<PAGE>

Municipal Obligations

Other Income-Producing Securities

Other types of income producing securities that the Portfolios may
purchase include, but are not limited to, the following types of
securities:

VARIABLE AND FLOATING RATE OBLIGATIONS. These types of securities have
variable or floating rates of interest and, under certain limited
circumstances, may have varying principal amounts. These securities
pay interest at rates that are adjusted periodically according to a
specified formula, usually with reference to some interest rate index
or market interest rate. The floating rate tends to decrease the
security's price sensitivity to changes in interest rates. These types
of securities are relatively long-term instruments that often carry
demand features permitting the holder to demand payment of principal
at any time or at specified intervals prior to maturity. In order to
most effectively use these investments, a portfolio manager must
correctly assess probable movements in interest rates. This involves
different skills than those used to select most portfolio securities.
If the portfolio manager incorrectly forecasts such movements, a
Portfolio could be adversely affected by the use of variable or
floating rate obligations.

The Portfolios will purchase standby commitments, tender option bonds
and instruments with demand features primarily for the purpose of
increasing the liquidity of their holdings.

Repurchase and Reverse Repurchase Agreements

8
<PAGE>

more than seven) from the date of purchase. The resale price consists
of the purchase price plus an agreed upon incremental amount that is
unrelated to the coupon rate or maturity of the purchased security. A
repurchase agreement involves the obligation of the seller to pay the
agreed upon price, which obligation is in effect secured by the value
(at least equal to the amount of the agreed upon resale price and
marked-to-market daily) of the underlying security or "collateral." A
risk associated with repurchase agreements is the failure of the
seller to repurchase the securities as agreed, which may cause a
Portfolio to suffer a loss if the market value of such securities
declines before they can be liquidated on the open market. In the
event of bankruptcy or insolvency of the seller, a Portfolio may
encounter delays and incur costs in liquidating the underlying
security. Repurchase agreements that mature in more than seven days
are subject to the 15% limit on illiquid investments. While it is not
possible to eliminate all risks from these transactions, it is the
policy of the Portfolios to limit repurchase agreements to those
parties whose creditworthiness has been reviewed and found
satisfactory by Janus Capital.

A Portfolio may use reverse repurchase agreements to obtain cash to
satisfy unusually heavy redemption requests or for other temporary or
emergency purposes without the necessity of selling portfolio
securities, or to earn additional income on portfolio securities, such
as Treasury bills or notes. In a reverse repurchase agreement, a
Portfolio sells a portfolio security to another party, such as a bank
or broker-dealer, in return for cash and agrees to repurchase the
instrument at a particular price and time. While a reverse repurchase
agreement is outstanding, a Portfolio will maintain cash and
appropriate liquid assets in a segregated custodial account to cover
its obligation under the agreement. The Portfolios will enter into
reverse repurchase agreements only with parties that Janus Capital
deems creditworthy. Using reverse repurchase agreements to earn
additional income involves the risk that the interest earned on the
invested proceeds is less than the expense of the reverse repurchase
agreement transaction. This technique may also have a leveraging
effect on the Portfolio, although the Portfolio's intent to segregate
assets in the amount of the reverse repurchase agreement minimizes
this effect.

High-Yield/High-Risk Bonds

9
<PAGE>

resumption of income, however, the purchase of any security on which
payment of interest or dividends is suspended involves a high degree
of risk. Such risk includes, among other things, the following:

Other. Defaulted securities require active monitoring and may, at
times, require participation in bankruptcy or receivership proceedings
on behalf of the Portfolios.

Futures, Options and Other Derivative Instruments

10
<PAGE>

trading in the futures markets. The Portfolios will use futures
contracts and related options primarily for bona fide hedging purposes
within the meaning of CFTC regulations. To the extent that the
Portfolios hold positions in futures contracts and related options
that do not fall within the definition of bona fide hedging
transactions, the aggregate initial margin and premiums required to
establish such positions will not exceed 5% of the fair market value
of a Portfolio's net assets, after taking into account unrealized
profits and unrealized losses on any such contracts it has entered
into.

A Portfolio's primary purpose in entering into futures contracts is to
protect that Portfolio from fluctuations in the value of securities or
interest rates without actually buying or selling the underlying debt
or equity security. For example, if the Portfolio anticipates an
increase in the price of stocks, and it intends to purchase stocks at
a later time, that Portfolio could enter into a futures contract to
purchase a stock index as a temporary substitute for stock purchases.
If an increase in the market occurs that influences the stock index as
anticipated, the value of the futures contracts will increase, thereby
serving as a hedge against that Portfolio not participating in a
market advance. This technique is sometimes known as an anticipatory
hedge. To the extent a Portfolio enters into futures contracts for
this purpose, the segregated assets maintained to cover such
Portfolio's obligations with respect to the futures contracts will
consist of liquid assets from its portfolio in an amount equal to the
difference between the contract price and the aggregate value of the
initial and variation margin payments made by that Portfolio with
respect to the futures contracts. Conversely, if a Portfolio holds
stocks and seeks to protect itself from a decrease in stock prices,
the Portfolio might sell stock index futures contracts, thereby hoping
to offset the potential decline in the value of its portfolio
securities by a corresponding increase in the value of the futures
contract position. A Portfolio could protect against a decline in
stock prices by selling portfolio securities and investing in money
market instruments, but the use of futures contracts enables it to
maintain a defensive position without having to sell portfolio
securities.

11
<PAGE>

price relationship between the cash and futures markets. Second, the
liquidity of the futures market depends on participants entering into
offsetting transactions rather than making or taking delivery of the
instrument underlying a futures contract. To the extent participants
decide to make or take delivery, liquidity in the futures market could
be reduced and prices in the futures market distorted. Third, from the
point of view of speculators, the margin deposit requirements in the
futures market are less onerous than margin requirements in the
securities market. Therefore, increased participation by speculators
in the futures market may cause temporary price distortions. Due to
the possibility of the foregoing distortions, a correct forecast of
general price trends by a portfolio manager still may not result in a
successful use of futures.

12
<PAGE>

existing positions. If the secondary market for a futures contract is
not liquid because of price fluctuation limits or otherwise, a
Portfolio may not be able to promptly liquidate unfavorable futures
positions and potentially could be required to continue to hold a
futures position until the delivery date, regardless of changes in its
value. As a result, such Portfolio's access to other assets held to
cover its futures positions also could be impaired.

The writing of a call option on a futures contract constitutes a
partial hedge against declining prices of the security or foreign
currency which is deliverable under, or of the index comprising, the
futures contract. If the futures price at the expiration of the option
is below the exercise price, a Portfolio will retain the full amount
of the option premium which provides a partial hedge against any
decline that may have occurred in that Portfolio's holdings. The
writing of a put option on a futures contract constitutes a partial
hedge against increasing prices of the security or foreign currency
which is deliverable under, or of the index comprising, the futures
contract. If the futures price at expiration of the option is higher
than the exercise price, a Portfolio will retain the full amount of
the option premium which provides a partial hedge against any increase
in the price of securities which that Portfolio is considering buying.
If a call or put option a Portfolio has written is exercised, such
Portfolio will incur a loss which will be reduced by the amount of the
premium it received. Depending on the degree of correlation between
the change in the value of its portfolio securities and changes in the
value of the futures positions, a Portfolio's losses from existing
options on futures may to some extent be reduced or increased by
changes in the value of portfolio securities.

13
<PAGE>

contract before its maturity, or may hold the contract to maturity and
complete the contemplated exchange.

14
<PAGE>

15
<PAGE>

16
<PAGE>

the purchase is that the writer's position will be canceled by the
clearing corporation. However, a writer may not effect a closing
purchase transaction after being notified of the exercise of an
option. Likewise, an investor who is the holder of an option may
liquidate its position by effecting a "closing sale transaction." This
is accomplished by selling an option of the same series as the option
previously bought. There is no guarantee that either a closing
purchase or a closing sale transaction can be effected.

A Portfolio will realize a profit from a closing transaction if the
price of the purchase transaction is less than the premium received
from writing the option or the price received from a sale transaction
is more than the premium paid to buy the option. A Portfolio will
realize a loss from a closing transaction if the price of the purchase
transaction is more than the premium received from writing the option
or the price received from a sale transaction is less than the premium
paid to buy the option. Because increases in the market of a call
option generally will reflect increases in the market price of the
underlying security, any loss resulting from the repurchase of a call
option is likely to be offset in whole or in part by appreciation of
the underlying security owned by a Portfolio.

17
<PAGE>

decline moderately during the option period. Buy-and-write
transactions using at-the-money call options may be used when it is
expected that the price of the underlying security will remain fixed
or advance moderately during the option period. Buy-and-write
transactions using out-of-the-money call options may be used when it
is expected that the premiums received from writing the call option
plus the appreciation in the market price of the underlying security
up to the exercise price will be greater than the appreciation in the
price of the underlying security alone. If the call options are
exercised in such transactions, a Portfolio's maximum gain will be the
premium received by it for writing the option, adjusted upwards or
downwards by the difference between that Portfolio's purchase price of
the security and the exercise price. If the options are not exercised
and the price of the underlying security declines, the amount of such
decline will be offset by the amount of premium received.

18
<PAGE>

there is a default by the other party to such a transaction, a
Portfolio will have contractual remedies pursuant to the agreements
related to the transaction.

19
<PAGE>

traded options on foreign currencies involve certain risks not
presented by the over-the-counter market. For example, exercise and
settlement of such options must be made exclusively through the OCC,
which has established banking relationships in applicable foreign
countries for this purpose. As a result, the OCC may, if it determines
that foreign governmental restrictions or taxes would prevent the
orderly settlement of foreign currency option exercises, or would
result in undue burdens on the OCC or its clearing member, impose
special procedures on exercise and settlement, such as technical
changes in the mechanics of delivery of currency, the fixing of dollar
settlement prices or prohibitions on exercise.

20
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Investment adviser

Global Life Sciences Portfolio and Global Technology Portfolio have
each agreed to compensate Janus Capital for its services by the
monthly payment of a fee at the annual rate of 0.75% of the first $300
million of the average daily net assets of each Portfolio, 0.70% of
the next $200 million of the average daily net assets of each
Portfolio and 0.65% on the average daily net assets of each Portfolio
in excess of $500 million. The advisory fee is calculated and payable
daily. Janus Capital has voluntarily agreed to cap the advisory fee of
Global Life Sciences Portfolio and Global Technology Portfolio at the
effective rate of Janus Global Life Sciences Fund and Janus Global
Technology Fund (the "retail funds"), respectively. The effective rate
of each retail fund is the advisory fee calculated by such fund on the
last day of each calendar quarter. If the assets of the corresponding
retail fund exceed the assets of a Portfolio as of the last day of any
calendar quarter, then the advisory fee payable by that Portfolio for
the following calendar quarter will be a flat rate equal to such
effective rate. The effective rate (annualized) of Janus Global Life
Sciences Fund and Janus Global Technology Fund were % and %,
respectively, for the quarter ended December 31, 1999. Janus Capital
has agreed to continue such reductions until at least the next annual
renewal of the advisory agreements.

In addition, Janus Capital has agreed to reimburse Global Life
Sciences Portfolio and Global Technology Portfolio by the amount, if
any, that such Portfolio's normal operating expenses in any fiscal
year, including the investment advisory fee but excluding the
distribution fee described below, brokerage commissions, interest,
taxes and extraordinary expenses, exceed an annual rate of 1.25% of
the average daily net assets of the Portfolio until at least the next
annual renewal of the advisory agreements. Mortality risk, expense
risk and other charges imposed by participating insurance companies
are also excluded from the above expense limitation.

21
<PAGE>

not be amended without the approval by vote of a majority of the
Trustees of the affected Portfolio, including the Trustees who are not
interested persons of that Portfolio or Janus Capital and, to the
extent required by the 1940 Act, the vote of a majority of the
outstanding voting securities of that Portfolio.

Kansas City Southern Industries, Inc. ("KCSI") owns approximately 82%
of the outstanding voting stock of Janus Capital, most of which it
acquired in 1984. KCSI is a publicly traded holding company whose
primary subsidiaries are engaged in transportation, information
processing and financial services. Thomas H. Bailey, President and
Chairman of the Board of Janus Capital, owns approximately 12% of its
voting stock and, by agreement with KCSI, selects a majority of Janus
Capital's Board.

[TO BE UPDATED] KCSI has announced its intention to separate its
transportation and financial services businesses. KCSI is currently
studying alternatives for completion of the separation that meet its
business objectives without risking adverse tax consequences. KCSI
expects completion of the separation to be contemplated in 1999.

The provisions of the policy are administered by and subject to
exceptions authorized by Janus Capital.

22
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Custodian, transfer agent and certain affiliations

Janus Service Corporation, P.O. Box 173375, Denver, Colorado
80217-3375, a wholly-owned subsidiary of Janus Capital, is the
Portfolios' transfer agent. In addition, Janus Service provides
certain other administrative, recordkeeping and shareholder relations
services to the Portfolios. Janus Service Corporation is not
compensated for its services related to the Shares, except for
out-of-pocket costs.

Janus Distributors, Inc., 100 Fillmore Street, Denver, Colorado
80206-4928, a wholly-owned subsidiary of Janus Capital, is the Trust's
distributor. Janus Distributors is registered as a broker-dealer under
the Securities Exchange Act of 1934 and is a member of the National
Association of Securities Dealers, Inc.

23
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Portfolio transactions and brokerage

24
<PAGE>

25
<PAGE>
Trustees and officers

The following are the names of the Trustees and officers of the Trust,
together with a brief description of their principal occupations
during the last five years.

TRUSTEES

Thomas H. Bailey, Age 62 - Trustee, Chairman and President*#
100 Fillmore Street
Denver, CO 80206-4928

James P. Craig, III, Age 43 - Trustee
100 Fillmore Street

Denver, CO 80206-4928
- --------------------------------------------------------------------------------

Gary O. Loo, Age 59 - Trustee#
102 N. Cascade, Suite 500

Dennis B. Mullen, Age 56 - Trustee

- --------------------------------------------------------------------------------
*Interested person of the Trust and of Janus Capital.
#Member of the Trust's Executive Committee.

26
<PAGE>

James T. Rothe, Age 56 - Trustee

William D. Stewart, Age 56 - Trustee#
5330 Sterling Drive

Boulder, CO 80302

- --------------------------------------------------------------------------------

Trustee of Janus Investment Fund. President of HPS Division of MKS
Instruments, Boulder, CO (manufacturer of vacuum fittings and valves).

Martin H. Waldinger, Age 61 - Trustee

4940 Sandshore Court

San Diego, CA 92130

- --------------------------------------------------------------------------------

Trustee of Janus Investment Fund. Private Consultant. Formerly
(1993-1996), Director of Run Technologies, Inc., a software
development firm, San Carlos, CA.

OFFICERS

C. Mike Lu, Age 30 - Executive Vice President*

100 Fillmore Street

Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Portfolio Manager of Janus Investment Fund. Formerly, research analyst
at Janus Capital (1991-1998).

Thomas R. Malley, Age 30 - Executive Vice President*

100 Fillmore Street

Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Portfolio Manager of Janus Investment Fund. Formerly, research analyst
at Janus Capital (1991-1998).

- --------------------------------------------------------------------------------

*Interested person of the Trust and of Janus Capital.

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<PAGE>

Thomas A. Early, Age 45 - Vice President and General Counsel*
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Steven R. Goodbarn, Age 42 - Vice President and Chief Financial Officer*
100 Fillmore Street
Denver, CO 80206-4928

Kelley Abbott Howes, Age 34 - Assistant Vice President and Secretary*
100 Fillmore Street
Denver, CO 80206-4928

- --------------------------------------------------------------------------------

Glenn P. O'Flaherty, Age 41 - Treasurer and Chief Accounting Officer*
100 Fillmore Street, Suite 300
Denver, CO 80206-4928

- --------------------------------------------------------------------------------
Treasurer and Chief Accounting Officer of Janus Investment Fund. Vice
President of Janus Capital. Formerly (1991-1997), Director of Fund
Accounting, Janus Capital.
----------------------------------------------------------------------
*Interested person of the Trust and of Janus Capital.

28
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<TABLE>
<CAPTION>
Aggregate Compensation Total Compensation
from the Portfolios for from the Janus Funds for
fiscal year ended calendar year ended
Name of Person, Position December 31, 1999 December 31, 1999**
- -----------------------------------------------------------------------------------------------------------------
<S> <C> <C>
Thomas H. Bailey, Chairman and Trustee* $ 0 $
James P. Craig, III, Trustee* $ 0 $
William D. Stewart, Trustee $ 0 $
Gary O. Loo, Trustee $ 0 $
Dennis B. Mullen, Trustee $ 0 $
Martin H. Waldinger, Trustee $ 0 $
James T. Rothe, Trustee $ 0 $
</TABLE>

* An interested person of the Portfolios and of Janus Capital. Compensated by
Janus Capital and not the Portfolios.

** As of December 31, 1999, Janus Funds consisted of two registered investment
companies comprised of a total of 32 funds.

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Shares of the trust

NET ASSET VALUE DETERMINATION

PURCHASES

Shares of the Portfolios can be purchased only by (i) the separate
accounts of participating insurance companies for the purpose of
funding variable insurance contracts and (ii) qualified retirement
plans. Participating insurance companies and certain designated
organizations are authorized to receive purchase orders on the
Portfolios' behalf and those organizations are authorized to designate
their agents and affiliates as intermediaries to receive purchase
orders. Purchase orders are deemed received by a Portfolio when
authorized organizations, their agents or affiliates receive the
order. The Portfolios are not responsible for the failure of any
designated organization or its agents or affiliates to carry out its
obligations to its customers. Shares of the Portfolios are purchased
at the NAV per Share as determined at the close of the regular trading
session of the NYSE next occurring after a purchase order is received
and accepted by a Portfolio or its authorized agent. In order to
receive a day's price, your order must be received by the close of the
regular trading session of the NYSE as described above in "Net Asset
Value Determination." The

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prospectus for your insurance company's separate account or your plan
documents contain detailed information about investing in the
different Portfolios.

DISTRIBUTION AND SHAREHOLDER SERVICING PLAN

Under a distribution and shareholder servicing plan ("Plan") adopted
in accordance with Rule 12b-1 under the 1940 Act, the Shares may pay
Janus Distributors, the Trust's distributor, a fee at an annual rate
of up to 0.25% of the average daily net assets of the Shares of a
Portfolio. Under the terms of the Plan, the Trust is authorized to
make payments to Janus Distributors for remittance to insurance
companies and qualified plan service providers as compensation for
distribution and shareholder servicing performed by such service
providers. The Plan is a compensation type plan and permits the
payment at an annual rate of up to 0.25% of the average daily net
assets of the Shares of a Portfolio for recordkeeping and
administrative services as well as activities which are primarily
intended to result in sales of the Shares, including but not limited
to preparing, printing and distributing prospectuses, Statements of
Additional Information, shareholder reports, and educational materials
to prospective and existing contract owners and plan participants;
responding to inquiries by contract owners and plan participants;
receiving and answering correspondence; contract owner and participant
level recordkeeping and administrative services; and similar
activities. On September 14, 1999, Trustees unanimously approved the
Plan which became effective on that date. The Plan and any Rule 12b-1
related agreement that is entered into by the Portfolios or Janus
Distributors in connection with the Plan will continue in effect for a
period of more than one year only so long as continuance is
specifically approved at least annually by a vote of a majority of the
Trustees, and of a majority of the Trustees who are not interested
persons (as defined in the 1940 Act) of the Trust and who have no
direct or indirect financial interest in the operation of the Plan or
any related agreements ("12b-1 Trustees"). All material amendments to
the Plan must be approved by a majority vote of the Trustees,
including a majority of the 12b-1 Trustees, at a meeting called for
that purpose. In addition, the Plan may be terminated at any time,
without penalty, by vote of a majority of the outstanding Shares of a
Portfolio or by vote of a majority of 12b-1 Trustees.

REDEMPTIONS

Redemptions, like purchases, may only be effected through the separate
accounts of participating insurance companies or qualified retirement
plans. Certain designated organizations are authorized to receive
redemption orders on the Portfolios' behalf and those organizations
are authorized to designate their agents and affiliates as
intermediaries to receive redemption orders. Redemption orders are
deemed received by a Portfolio when authorized organizations, their
agents or affiliates receive the order. The Portfolios are not
responsible for the failure of any designated organization or its
agents or affiliates to carry out its obligations to its customers.
Shares normally will be redeemed for cash, although each Portfolio
retains the right to redeem its shares in kind under unusual
circumstances, in order to protect the interests of remaining
shareholders, by delivery of securities selected from its assets at
its discretion. However, the Portfolios are governed by Rule 18f-1
under the 1940 Act, which requires each Portfolio to redeem shares
solely in cash up to the lesser of $250,000 or 1% of the NAV of that
Portfolio during any 90-day period for any one shareholder. Should
redemptions by any shareholder exceed such limitation, a Portfolio
will have the option of redeeming the excess in cash or in kind. If
shares are redeemed in kind, the redeeming shareholder might incur
brokerage costs in converting the assets to cash. The method of
valuing securities used to make redemptions in kind will be the same
as the method of valuing portfolio securities described under "Shares
of the Trust - Net Asset Value Determination" and such valuation will
be made as of the same time the redemption price is determined.

31
<PAGE>

32
<PAGE>
Income dividends, capital gains distributions and tax status

It is a policy of the Shares of the Portfolios to distribute
substantially all of their respective investment income at least
semi-annually and their respective net realized gains, if any, at
least annually. The Portfolios intend to qualify as regulated
investment companies by satisfying certain requirements prescribed by
Subchapter M of the Internal Revenue Code ("Code"). In addition, each
Portfolio intends to comply with the diversification requirements of
Code Section 817(h) related to the tax-deferred status of insurance
company separate accounts.

Because Shares of the Portfolios can only be purchased through
variable insurance contracts or qualified plans, it is anticipated
that any income dividends or capital gains distributions will be
exempt from current taxation if left to accumulate within such plans.
See the prospectus for the separate account of the related insurance
company or the plan documents for additional information.

33
<PAGE>
Miscellaneous information

SHARES OF THE TRUST

The Portfolios each offer two classes of shares. The Shares discussed
in this SAI are offered only in connection with investment in and
payments under variable insurance contracts and to qualified
retirement plans that require a fee from Portfolio assets to procure
distribution and administrative services to contract owners and plan
participants. The second class of shares, Institutional Shares, is
offered only in connection with investments in and payments under
variable insurance contracts as well as other qualified retirement
plans.

SHAREHOLDER MEETINGS

The Trust does not intend to hold annual shareholder meetings.
However, special meetings may be called for a specific Portfolio or
for the Trust as a whole for purposes such as electing or removing
Trustees, terminating or reorganizing the Trust, changing fundamental
policies, or for any other purpose requiring a shareholder vote under
the 1940 Act. Separate votes are taken by each Portfolio or class only
if a matter affects or requires the vote of only that Portfolio or
class or that Portfolio's or class' interest in the matter differs
from the interest of other Portfolios of the Trust. A shareholder is
entitled to one vote for each Share owned.

VOTING RIGHTS

34
<PAGE>

INDEPENDENT ACCOUNTANTS

REGISTRATION STATEMENT

35
<PAGE>
Performance information

From time to time in advertisements or sales material, the Portfolios
may discuss their performance ratings or other information as
published by recognized mutual fund statistical rating services,
including, but not limited to, Lipper Analytical Services, Inc.,
Ibbotson Associates, Micropal or Morningstar, Inc. or by publications
of general interest such as Forbes, Money, The Wall Street Journal,
Mutual Funds Magazine, Kiplinger's or Smart Money. The Portfolios may
also compare their performance to that of other selected mutual funds
(for example, peer groups created by Lipper or Morningstar), mutual
fund averages or recognized stock market indicators, including, but
not limited to, the Standard & Poor's 500 Composite Stock Price Index,
the Dow Jones Industrial Average, the and the NASDAQ composite. Global
Life Sciences and Global Technology Portfolios may also compare their
performance to the record of global market indicators, such as the
Morgan Stanley International World Index or Morgan Stanley Capital
International Europe, Australasia, Far East Index (EAFE Index). Such
performance ratings or comparisons may be made with funds that may
have different investment restrictions, objectives, policies or
techniques than the Portfolios and such other funds or market
indicators may be comprised of securities that differ significantly
from the Portfolios' investments.

36
<PAGE>
Appendix A

EXPLANATION OF RATING CATEGORIES

STANDARD & POOR'S
RATINGS SERVICES

MOODY'S INVESTORS SERVICE, INC.

37
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38
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<PAGE>

LOGO

1-800-525-0020

100 Fillmore Street
Denver, Colorado 80206-4928
janus.com

<PAGE>

JANUS ASPEN SERIES

PART C - OTHER INFORMATION
ITEM 23 Exhibits

Exhibit 1 (a) Trust Instrument dated May 19, 1993, is
incorporated herein by reference to Registrant's
Registration Statement on Form N-1A filed with the
Securities and Exchange Commission on May 20,
1993.

(b) Amendments to Trust Instrument are incorporated
herein by reference to Exhibit 1(b) to
Post-Effective Amendment No. 7, filed on February
14, 1996.

(c) Amendment to Trust Instrument dated December 10,
1996 is incorporated herein by reference to
Exhibit 1(c) to Post-Effective Amendment No. 10,
filed on February 13, 1997.

(d) Amendment to Trust Instrument dated September 14,
1999 is incorporated herein by reference to
Exhibit 1(d) to Post-Effective Amendment No. 20,
filed on October 26, 1999.

(e) Amendment to Trust Instrument dated December 14,
1999 is filed herein as Exhibit 1(e).

Exhibit 2 (a) Restated Bylaws are incorporated herein by
reference to Exhibit 2(a) to Post-Effective
Amendment No. 7, filed on February 14, 1996.

(b) First Amendment to the Bylaws is incorporated
herein by reference to Exhibit 2(b) to
Post-Effective Amendment No. 7, filed on February
14, 1996.

Exhibit 3 Not Applicable

Exhibit 4 (a) Investment Advisory Agreement for Growth
Portfolio, Aggressive Growth Portfolio, Worldwide
Growth Portfolio, Balanced Portfolio, Flexible
Income Portfolio and Short-Term Bond Portfolio is
incorporated herein by reference to Exhibit 5(a)
to Post-Effective Amendment No. 15, filed on
February 27, 1998.

(b) Investment Advisory Agreement for International
Growth Portfolio is incorporated herein by
reference to Exhibit 5(b)

<PAGE>

to Post-Effective Amendment No. 15, filed on
February 27, 1998.

(c) Investment Advisory Agreement for Money Market
Portfolio is incorporated herein by reference to
Exhibit 5(c) to Post-Effective Amendment No. 15,
filed on February 27, 1998.

(d) Investment Advisory Agreement for High-Yield
Portfolio is incorporated herein by reference to
Exhibit 5(d) to Post-Effective Amendment No. 15,
filed on February 27, 1998.

(e) Investment Advisory Agreement for Equity Income
Portfolio is incorporated herein by reference to
Exhibit 5(e) to Post-Effective Amendment No. 15,
filed on February 27, 1998.

(f) Investment Advisory Agreement for Capital
Appreciation Portfolio is incorporated herein by
reference to Exhibit 5(f) to Post-Effective
Amendment No. 15, filed on February 27, 1998.

(g) Form of Investment Advisory Agreement for Growth
and Income Portfolio is incorporated herein by
reference to Exhibit 5(g) to Post-Effective
Amendment No. 12, filed on August 11, 1997.

(h) Form of Investment Advisory Agreement for Global
Life Sciences Portfolio is filed herein as Exhibit
4(h).

(i) Form of Investment Advisory Agreement for Global
Technology Portfolio is filed herein as Exhibit
4(i).

Exhibit 5 (a) Distribution Agreement for Retirement Shares is
incorporated herein by reference to Exhibit 6(a)
to Post-Effective Amendment No. 10, filed on
February 13, 1997.

(b) Form of Distribution and Shareholder Services
Agreement for Retirement Shares is incorporated
herein by reference to Post-Effective Amendment
No. 11, filed on April 30, 1997.

<PAGE>
(d) Amended Distribution Agreement dated September 14,
1999 is incorporated herein by reference to
Post-Effective Amendment No. 20, filed on October
26, 1999.

(e) Form of Distribution and Shareholder Services
Agreement for Service Shares for Qualified Plans
is incorporated herein by reference to
Post-Effective Amendment No. 20, filed on October
26, 1999.

(f) Form of Distribution and Shareholder Services
Agreement for Service Shares for Insurance
Companies is incorporated herein by reference to
Post-Effective Amendment No. 20, filed on October
26, 1999.

Exhibit 6 Not Applicable

Exhibit 7 (a) Form of Custody Agreement between Janus Aspen
Series and Investors Fiduciary Trust Company is
incorporated herein by reference to Exhibit 8(a)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

(b) Form of Custodian Contract between Janus Aspen
Series and State Street Bank and Trust Company is
incorporated herein by reference to Exhibit 8(b)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

(c) Letter Agreement dated April 4, 1994 regarding
State Street Custodian Agreement is incorporated
herein by reference to Exhibit 8(c) to
Post-Effective Amendment No. 11, filed on April
30, 1997.

(d) Form of Custodian Agreement between Janus Aspen
Series and United Missouri Bank, N.A. is
incorporated herein by reference to Exhibit 8(d)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

(e) Amendment dated October 11, 1995 of State Street
Custodian Contract is incorporated herein by
reference to Exhibit 8(e) to Post-Effective
Amendment No. 7, filed on February 14, 1996.

<PAGE>

(f) Letter Agreement dated September 10, 1996
regarding State Street Custodian is incorporated
herein by reference to Exhibit 8(f) to
Post-Effective Amendment No. 9, filed on October
24, 1996.

(g) Form of Subcustodian Contract between United
Missouri Bank, N.A. and State Street Bank and
Trust Company is incorporated herein by reference
to Exhibit 8(g) to Post-Effective Amendment No. 9,
filed on October 24, 1996.

(h) Form of Letter Agreement dated September 9, 1997,
regarding State Street Custodian Contract is
incorporated herein by reference to Exhibit 8(h)
to Post-Effective Amendment No. 14, filed on
October 24, 1997.

(i) Form of Global Custody Services Agreement dated
March 11, 1999 with Citibank N.A. is incorporated
herein by reference to Exhibit 7 to Post-Effective
Amendment No. 19, filed on April 30, 1999.

Exhibit 8 (a) Transfer Agency Agreement with Janus Service
Corporation is incorporated herein by reference to
Exhibit 9(a) to Post-Effective Amendment No. 11,
filed on April 30, 1997.

(b) Transfer Agency Agreement as amended May 1, 1997
is incorporated herein by reference to Exhibit
9(b) to Post-Effective Amendment No. 10, filed on
February 13, 1997.

(c) Form of Model Participation Agreement is
incorporated herein by reference to Exhibit 9(c)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

Exhibit 9 (a) Opinion and Consent of Fund Counsel with respect
to shares of Growth Portfolio, Aggressive Growth
Portfolio, Worldwide Growth Portfolio, Balanced
Portfolio, Flexible Income Portfolio and
Short-Term Bond Portfolio is incorporated herein
by reference to Exhibit 10 to Post-Effective
Amendment No. 11, filed on April 30, 1997.

(b) Opinion and Consent of Fund Counsel with respect
to shares of International Growth Portfolio is
incorporated herein by reference to Exhibit 10(b)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

<PAGE>

(c) Opinion and Consent of Fund Counsel with respect
to shares of Money Market Portfolio is
incorporated herein by reference to Exhibit 10(c)
to Post-Effective Amendment No. 11, filed on April
30, 1997.

(d) Opinion and Consent of Fund Counsel with respect
to High-Yield Portfolio is incorporated herein by
reference to Exhibit 10(d) to Post-Effective
Amendment No. 7, filed on February 14, 1996.

(e) Opinion and Consent of Fund Counsel with respect
to Equity Income Portfolio and Capital
Appreciation Portfolio is incorporated herein by
reference to Exhibit 10(e) to Post-Effective
Amendment No. 10, filed on February 13, 1997.

(f) Opinion and Consent of Fund Counsel with respect
to the Retirement Shares of all the Portfolios is
incorporated herein by reference to Exhibit 10(f)
to Post-Effective Amendment No. 10, filed on
February 13, 1997.

(g) Opinion and Consent of Fund Counsel with respect
to Growth and Income Portfolio is incorporated
herein by reference to Exhibit 10(g) to
Post-Effective Amendment No. 12, filed on August
11, 1997.

(h) Opinion and Consent of Fund Counsel with respect
to Retirement Shares of Growth and Income
Portfolio is incorporated herein by reference to
Exhibit 10(h) to Post-Effective Amendment No. 12,
filed on August 11, 1997.

(i) Opinion and Consent of Fund Counsel with respect
to Service Shares of all the Portfolios is
incorporated herein by reference to Exhibit 9(I)
to Post-Effective 20, filed on October 26, 1999.

(j) Opinion and Consent of Fund Counsel with respect
to Global Life Sciences Portfolio and Global
Technology Portfolio for Service Shares and
Institutional Shares is filed herein as Exhibit
9(j).

Exhibit 10 Consent of PricewaterhouseCoopers LLP is filed
herein as Exhibit 10.

<PAGE>

Exhibit 11 Not Applicable

Exhibit 12 Not Applicable

Exhibit 13 (a) Form of Distribution and Shareholder Servicing
Plan for Retirement Shares dated May 1, 1997
between Janus Distributors, Inc. and Janus Aspen
Series is incorporated herein by reference to
Exhibit 15 to Post-Effective Amendment No. 10,
filed on February 13, 1997.

(b) Form of Distribution and Shareholder Servicing
Plan for Service Shares between Janus
Distributors, Inc. and Janus Aspen Series is
incorporated herein by reference to Exhibit 13(b)
to Post-Effective Amendment No. 20, filed on
October 26, 1999.

Exhibit 14 Not Applicable

Exhibit 15 (a) Rule 18f-3 Plan dated December 10, 1996 is
incorporated herein by reference to Exhibit 18 to
Post-Effective Amendment No. 10, filed on February
13, 1997.

(b) Rule 18f-3 Plan dated June 15, 1999 is filed
incorporated herein by reference to Exhibit 15 to
Post-Effective Amendment No. 19, filed on June 21,
1999.

(c) Rule 18f-3 Plan dated September 14, 1999 is
incorporated herein by reference to Exhibit 15(c)
to Post-Effective Amendment No. 20, filed on
October 26, 1999.

ITEM 24. Persons Controlled by or Under Common Control with Registrant

None

ITEM 25. Indemnification

Article IX of Janus Aspen Series' Trust Instrument provides for
indemnification of certain persons acting on behalf of the Portfolios. In
general, Trustees and officers will be indemnified against liability and against
all expenses of litigation incurred by them in connection with any claim,
action, suit or proceeding (or settlement of the same) in which they become
involved by virtue of their office in connection with the Portfolios, unless
their conduct is determined to constitute willful misfeasance, bad faith, gross
negligence or reckless disregard of their duties, or unless it has been
determined that they have not acted in good faith in the reasonable belief that
their actions were in the best interests of the Portfolios. A determination that
a person covered

<PAGE>

by the indemnification provisions is entitled to indemnification may be made by
the court or other body before which the proceeding is brought, or by either a
vote of a majority of a quorum of Trustees who are neither "interested persons"
of the Trust nor parties to the proceeding or by an independent legal counsel in
a written opinion. The Portfolios also may advance money for these expenses,
provided that the Trustee or officer undertakes to repay the Portfolios if his
conduct is later determined to preclude indemnification, and that either he
provide security for the undertaking, the Trust be insured against losses
resulting from lawful advances or a majority of a quorum of disinterested
Trustees, or independent counsel in a written opinion, determines that he
ultimately will be found to be entitled to indemnification. The Trust also
maintains a liability insurance policy covering its Trustees and officers.

ITEM 26. Business and Other Connections of Investment Adviser

The only business of Janus Capital Corporation is to serve as the
investment adviser of the Registrant and as investment adviser or subadviser to
several other mutual funds, and for individual, charitable, corporate, private
and retirement accounts. Business backgrounds of the principal executive
officers and directors of the adviser that also hold positions with the
Registrant are included under "Officers and Trustees" in the currently effective
Statements of Additional Information of the Registrant. The remaining principal
executive officers of the investment adviser and their positions with the
adviser and affiliated entities are: Mark B. Whiston, Vice President and Chief
Marketing Officer of Janus Capital Corporation, Director and President of Janus
Capital International Ltd., Director of Janus World Funds Plc; Marjorie G. Hurd,
Vice President and Chief Operations Officer of Janus Capital Corporation,
Director and President of Janus Service Corporation; Thomas A. Early, Vice
President, General Counsel and Secretary of Janus Capital Corporation, Vice
President and General Counsel of Janus Service Corporation, Janus Distributors,
Inc. and Janus Capital International, Ltd., Director of Janus World Funds Plc,
and Stephen L. Stieneker, Assistant General Counsel, Chief Compliance Officer
and Vice President of Compliance of Janus Capital Corporation. Mr. Michael E.
Herman, a director of Janus Capital Corporation, is Chairman of the Finance
Committee (1990 to present) of Ewing Marion Kauffman Foundation, 4900 Oak,
Kansas City, Missouri 64112. Mr. Michael N. Stolper, a director of Janus Capital
Corporation, is President of Stolper & Company, Inc., 525 "B" Street, Suite
1080, San Diego, California 92101, an investment performance consultant. Mr.
Thomas A. McDonnell, a director of Janus Capital Corporation, is President,
Chief Executive Officer and a Director of DST Systems, Inc., 333 West 11th
Street, 5th Floor, Kansas City, Missouri 64105, provider of data processing and
recordkeeping services for various mutual funds, and is Executive Vice President
and a director of Kansas City Southern Industries, Inc., 114 W. 11th Street,
Kansas City, Missouri 64105, a publicly traded holding company whose primary
subsidiaries are engaged in transportation and financial services. Mr. Landon H.
Rowland, a director of Janus Capital Corporation, is President and Chief
Executive Officer of Kansas City Southern Industries, Inc.

<PAGE>

ITEM 27. Principal Underwriters

(a) Janus Distributors, Inc. ("Janus Distributors") serves as
principal underwriter for the Registrant and Janus
Investment Fund.

(b) The principal business address, positions with Janus
Distributors and positions with Registrant of Thomas A.
Early, Kelley Abbott Howes and Steven R. Goodbarn, officers
and directors of Janus Distributors, are described under
"Officers and Trustees" in the Statement of Additional
Information included in this Registration Statement. The
remaining principal executive officer of Janus Distributors
is Marjorie G. Hurd, Director and President. Ms. Hurd does
not hold any positions with the Registrant. Ms. Hurd's
principal business address is 100 Fillmore Street, Denver,
Colorado 80206-4928.

ITEM 28. Location of Accounts and Records

The accounts, books and other documents required to be maintained by
Section 31(a) of the Investment Company Act of 1940 and the rules promulgated
thereunder are maintained by Janus Capital Corporation and Janus Service
Corporation, both of which are located at 100 Fillmore Street, Denver, Colorado
80206-4928 and by State Street Bank and Trust Company, P.O. Box 0351, Boston,
Massachusetts 02117-0351 and Citibank, N.A., 111 Wall Street, 24th Floor, Zone
5, New York, NY 10043.

ITEM 29. Management Services

The Registrant has no management-related service contract which is not
discussed in Part A or Part B of this form.

ITEM 30. Undertakings

Not applicable.

<PAGE>

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the
Investment Company Act of 1940, the Registrant has duly caused this Amendment to
its Registration Statement to be signed on its behalf by the undersigned,
thereto duly authorized, in the City of Denver, and State of Colorado, on the
1st of November, 1999.

JANUS ASPEN SERIES

By: /s/ Thomas H. Bailey
Thomas H. Bailey, President

Janus Aspen Series is organized under a Trust Instrument dated May 19,
1993. The obligations of the Registrant hereunder are not binding upon any of
the Trustees, shareholders, nominees, officers, agents or employees of the
Registrant personally, but bind only the trust property of the Registrant, as
provided in the Trust Instrument. The execution of this Amendment to the
Registration Statement has been authorized by the Trustees of the Registrant and
this Amendment to the Registration Statement has been signed by an authorized
officer of the Registrant, acting as such, and neither such authorization by
such Trustees nor such execution by such officer shall be deemed to have been
made by any of them personally, but shall bind only the trust property of the
Registrant as provided in its Trust Instrument.

Pursuant to the requirements of the Securities Act of 1933, this Amendment
to the Registration Statement has been signed below by the following persons in
the capacities and on the dates indicated.

Signature Title Date

/s/ Thomas H. Bailey President November 1, 1999
Thomas H. Bailey (Principal Executive
Officer) and Trustee

/s/ Steven R. Goodbarn Vice President and November 1, 1999
Steven R. Goodbarn Chief Financial Officer
(Principal Financial Officer)

/s/ Glenn P. O'Flaherty Treasurer and Chief November 1, 1999
Glenn P. O'Flaherty Accounting Officer
(Principal Accounting Officer)

<PAGE>

/s/ James P. Craig, III Trustee November 1, 1999
James P. Craig, III

Gary O. Loo* Trustee November 1, 1999
Gary O. Loo

Dennis B. Mullen* Trustee November 1, 1999
Dennis B. Mullen

James T. Rothe* Trustee November 1, 1999
James T. Rothe

William D. Stewart* Trustee November 1, 1999
William D. Stewart

Martin H. Waldinger* Trustee November 1, 1999
Martin H. Waldinger

/s/ Steven R. Goodbarn
*By Steven R. Goodbarn
Attorney-in-Fact

<PAGE>

INDEX OF EXHIBITS

Exhibit Number Exhibit Title

Exhibit 1(e) Amendment to Trust Instrument dated
December 14, 1999

Exhibit 4(h) Form of Investment Advisory Agreement
for Global Life Sciences Portfolio

Exhibit 4(i) Form of Investment Advisory Agreement
for Global Technology Portfolio

Exhibit 9(j) Opinion and Consent of Fund Counsel with
respect to Global Life Sciences
Portfolio and Global Technology
Portfolio

Exhibit 10 Consent of PricewaterhouseCoopers LLP

Exhibit 1(e)

EIGHTH AMENDMENT DATED DECEMBER 14, 1999

TO JANUS ASPEN SERIES TRUST INSTRUMENT DATED MAY 19, 1993

Pursuant to authority granted by the Trustees, Schedule A of the Trust
Instrument is amended as follows to reflect the addition of the Global Life
Sciences Portfolio and the Global Technology Portfolio as series of Janus Aspen
Series:

SCHEDULE A

Series of the Trust Available Classes

Aggressive Growth Portfolio Institutional Shares
Retirement Shares
Service Shares

Balanced Portfolio Institutional Shares
Retirement Shares
Service Shares

Capital Appreciation Portfolio Institutional Shares
Retirement Shares
Service Shares

Equity Income Portfolio Institutional Shares
Retirement Shares
Service Shares

Flexible Income Portfolio Institutional Shares
Retirement Shares
Service Shares

Global Life Sciences Portfolio Institutional Shares
Retirement Shares

Global Technology Portfolio Institutional Shares
Retirement Shares

Growth Portfolio Institutional Shares
Retirement Shares
Service Shares

Growth and Income Portfolio Institutional Shares
Retirement Shares
Service Shares

<PAGE>

High-Yield Portfolio Institutional Shares
Retirement Shares
Service Shares

International Growth Portfolio Institutional Shares
Retirement Shares
Service Shares

Money Market Portfolio Institutional Shares
Retirement Shares
Service Shares

Worldwide Growth Portfolio Institutional Shares
Retirement Shares
Service Shares

[SEAL]

Exhibit 4(h)

JANUS ASPEN SERIES

INVESTMENT ADVISORY AGREEMENT

GLOBAL LIFE SCIENCES PORTFOLIO

THIS INVESTMENT ADVISORY AGREEMENT (the "Agreement") is made this ___ th
day of __________ , 1999, between JANUS ASPEN SERIES, a Delaware business trust
(the "Trust"), and JANUS CAPITAL CORPORATION, a Colorado corporation ("JCC").

W I T N E S S E T H:

WHEREAS, the Trust is registered as an open-end management investment
company under the Investment Company Act of 1940, as amended (the "1940 Act"),
and has registered its shares for public offering under the Securities Act of
1933, as amended (the "1933 Act"); and

WHEREAS, the Trust is authorized to create separate funds, each with its
own separate investment portfolio of which the beneficial interests are
represented by a separate series of shares; one of such funds created by the
Trust being designated as the Global Life Sciences Portfolio (the "Fund"); and

WHEREAS, the Trust and JCC deem it mutually advantageous that JCC should
assist the Trustees and officers of the Trust in the management of the
securities portfolio of the Fund.

NOW, THEREFORE, the parties agree as follows:

1. Investment Advisory Services. JCC shall furnish continuous advice and
recommendations to the Fund as to the acquisition, holding, or disposition of
any or all of the securities or other assets which the Fund may own or
contemplate acquiring from time to time. JCC shall give due consideration to the
investment policies and restrictions and the other statements concerning the
Fund in the Trust Instrument, bylaws, and registration statements under the 1940
Act and the 1933 Act, and to the provisions of the Internal Revenue Code, as
amended from time to time, applicable to the Fund as a regulated investment
company and as a funding vehicle for variable insurance contracts. In addition,
JCC shall cause its officers to attend meetings and furnish oral or written
reports, as the Trust may reasonably require, in order to keep the Trustees and
appropriate officers of the Trust fully informed as to the condition of the
investment portfolio of the Fund, the investment recommendations of JCC, and the
investment considerations which have given rise to those recommendations. JCC
shall supervise the purchase and sale of securities as directed by the
appropriate officers of the Trust.

2. Other Services. JCC is hereby authorized (to the extent the Trust
has not otherwise contracted) but not obligated (to the extent it so notifies
the Trustees at least 60 days in advance), to perform (or arrange for the
performance by affiliates of) the management and administrative services
necessary for the operation of the Fund. JCC is specifically authorized, on
behalf of the Trust, to conduct relations with custodians, depositories,
transfer and pricing agents, accountants,

<PAGE>

attorneys, underwriters, brokers and dealers, corporate fiduciaries, insurance
company separate accounts, insurers, banks and such other persons in any such
other capacity deemed by JCC to be necessary or desirable. JCC shall generally
monitor and report to Fund officers the Fund's compliance with investment
policies and restrictions as set forth in the currently effective prospectus and
statement of additional information relating to the shares of the Fund under the
Securities Act of 1933, as amended. JCC shall make reports to the Trustees of
its performance of services hereunder upon request therefor and furnish advice
and recommendations with respect to such other aspects of the business and
affairs of the Fund as it shall determine to be desirable. JCC is also
authorized, subject to review by the Trustees, to furnish such other services as
JCC shall from time to time determine to be necessary or useful to perform the
services contemplated by this Agreement.

3. Obligations of Trust. The Trust shall have the following obligations
under this Agreement:

(a) to keep JCC continuously and fully informed as to the composition
of its investment portfolio and the nature of all of its assets
and liabilities from time to time;

(b) to furnish JCC with a certified copy of any financial statement
or report prepared for it by certified or independent public
accountants and with copies of any financial statements or
reports made to its shareholders or to any governmental body or
securities exchange;

(c) to furnish JCC with any further materials or information which
JCC may reasonably request to enable it to perform its function
under this Agreement; and

(d) to compensate JCC for its services and reimburse JCC for its
expenses incurred hereunder in accordance with the provisions
hereof.

4. Compensation. The Trust shall pay to JCC for its investment advisory
services a fee, calculated and payable for each day that this Agreement is in
effect, of 1/365 of 0.75% of the first $300,000,000 of the daily closing net
asset value of the Fund, plus 1/365 of 0.70% of the next $200,000,000 of the
daily closing net asset value of the Fund, plus 1/365 of 0.65% of the daily
closing net asset value of the Fund in excess of $500,000,000.

5. Expenses Borne by JCC. In addition to the expenses which JCC may incur
in the performance of its investment advisory functions under this Agreement,
and the expenses which it may expressly undertake to incur and pay under other
agreements with the Trust or otherwise, JCC shall incur and pay the following
expenses relating to the Fund's operations without reimbursement from the Fund:

(a) Reasonable compensation, fees and related expenses of the Trust's
officers and its Trustees, except for such Trustees who are not
interested persons of JCC;

<PAGE>

(b) Rental of offices of the Trust; and

(c) All expenses of promoting the sale of shares of the Fund other
than expenses incurred in complying with federal and state laws,
including insurance laws, and the laws of any foreign country or
territory or other jurisdiction applicable to the issue, offer or
sale of shares of the Fund including without limitation
registration fees and costs, the costs of preparing the Fund's
registration statement and amendments thereto, and the costs and
expenses of preparing, printing, and mailing prospectuses (and
statements of additional information) to shareholders of the
Fund.

6. Expenses Borne by the Trust. The Trust assumes and shall pay all
expenses incidental to its organization, operations and business not
specifically assumed or agreed to be paid by JCC pursuant to Sections 2 and 5
hereof, including, but not limited to, investment adviser fees; any
compensation, fees, or reimbursements which the Trust pays to its Trustees who
are not interested persons of JCC; compensation of the Fund's custodian,
transfer agent, registrar and dividend disbursing agent; legal, accounting,
audit and printing expenses; administrative, clerical, recordkeeping and
bookkeeping expenses; brokerage commissions and all other expenses in connection
with execution of portfolio transactions (including any appropriate commissions
paid to JCC or its affiliates for effecting exchange listed, over-the-counter or
other securities transactions); interest; all federal, state and local taxes
(including stamp, excise, income and franchise taxes); costs of stock
certificates and expenses of delivering such certificates to purchasers thereof;
expenses of local representation in Delaware; expenses of shareholders' meetings
and of preparing, printing and distributing proxy statements, notices, and
reports to shareholders; expenses of preparing and filing reports and tax
returns with federal and state regulatory authorities; all expenses incurred in
complying with all federal and state laws and the laws of any foreign country
applicable to the issue, offer, or sale of shares of the Fund, including, but
not limited to, all costs involved in the registration or qualification of
shares of the Fund for sale in any jurisdiction, the costs of portfolio pricing
services and compliance systems, and all costs involved in preparing, printing
and mailing prospectuses and statements of additional information of the Fund;
and all fees, dues and other expenses incurred by the Trust in connection with
the membership of the Trust in any trade association or other investment company
organization. To the extent that JCC shall perform any of the above described
administrative and clerical functions, including transfer agency, registry,
dividend disbursing, recordkeeping, bookkeeping, accounting and blue sky
monitoring and registration functions, and the preparation of reports and
returns, the Trust shall pay to JCC compensation for, or reimburse JCC for its
expenses incurred in connection with, such services as JCC and the Trust shall
agree from time to time, any other provision of this Agreement notwithstanding.

7. Treatment of Investment Advice. The Trust shall treat the investment
advice and recommendations of JCC as being advisory only, and shall retain full
control over its own investment policies. However, the Trustees may delegate to
the appropriate officers of the Trust, or to a committee of the Trustees, the
power to authorize purchases, sales or other actions affecting the portfolio of
the Fund in the interim between meetings of the Trustees.

<PAGE>

8. Termination. This Agreement may be terminated at any time, without
penalty, by the Trustees of the Trust, or by the shareholders of the Trust
acting by vote of at least a majority of its outstanding voting securities,
provided in either case that sixty (60) days advance written notice of
termination be given to JCC at its principal place of business. This Agreement
may be terminated by JCC at any time, without penalty, by giving sixty (60) days
advance written notice of termination to the Trust, addressed to its principal
place of business. The Trust agrees that, consistent with the terms of the Trust
Instrument, the Trust shall cease to use the name "Janus" in connection with the
Fund as soon as reasonably practicable following any termination of this
Agreement if JCC does not continue to provide investment advice to the Fund
after such termination.

9. Assignment. This Agreement shall terminate automatically in the event of
any assignment of this Agreement.

10. Term. This Agreement shall continue in effect until July 1, 2001,
unless sooner terminated in accordance with its terms, and shall continue in
effect from year to year thereafter only so long as such continuance is
specifically approved at least annually by the vote of a majority of the
Trustees of the Trust who are not parties hereto or interested persons of any
such party, cast in person at a meeting called for the purpose of voting on the
approval of the terms of such renewal, and by either the Trustees of the Trust
or the affirmative vote of a majority of the outstanding voting securities of
the Trust. The annual approvals provided for herein shall be effective to
continue this Agreement from year to year if given within a period beginning not
more than ninety (90) days prior to July 1 of each applicable year,
notwithstanding the fact that more than three hundred sixty-five (365) days may
have elapsed since the date on which such approval was last given.

11. Amendments. This Agreement may be amended by the parties only if such
amendment is specifically approved (i) by a majority of the Trustees, including
a majority of the Trustees who are not interested persons (as that phrase is
defined in Section 2(a)(19) of the 1940 Act) of JCC and, if required by
applicable law, (ii) by the affirmative vote of a majority of the outstanding
voting securities of the Fund (as that phrase is defined in Section 2(a)(42) of
the 1940 Act).

12. Other Series. The Trustees shall determine the basis for making an
appropriate allocation of the Trust's expenses (other than those directly
attributable to the Fund) between the Fund and the other series of the Trust.

13. Limitation of Personal Liability. All the parties hereto acknowledge
and agree that all liabilities of the Trust arising, directly or indirectly,
under this Agreement, of any and every nature whatsoever, shall be satisfied
solely out of the assets of the Fund and that no Trustee, officer or holder of
shares of beneficial interest of the Trust shall be personally liable for any of
the foregoing liabilities. The Trust Instrument describes in detail the
respective responsibilities and limitations on liability of the Trustees,
officers and holders of shares of beneficial interest of the Trust.

<PAGE>

of its duties, or by reason of reckless disregard of its obligations and duties
hereunder and except to the extent otherwise provided by law. As used in this
Section 15, "JCC" shall include any affiliate of JCC performing services for the
Trust contemplated hereunder and directors, officers and employees of JCC and
such affiliates.

15. Activities of JCC. The services of JCC to the Trust hereunder are not
to be deemed to be exclusive, and JCC and its affiliates are free to render
services to other parties. It is understood that trustees, officers and
shareholders of the Trust are or may become interested in JCC as directors,
officers and shareholders of JCC, that directors, officers, employees and
shareholders of JCC are or may become similarly interested in the Trust, and
that JCC may become interested in the Trust as a shareholder or otherwise.

16. Certain Definitions. The terms "vote of a majority of the outstanding
voting securities", "assignment" and "interested persons" when used herein,
shall have the respective meanings specified in the 1940 Act, as now in effect
or hereafter amended, and the rules and regulations thereunder, subject to such
orders, exemptions and interpretations as may be issued by the Securities and
Exchange Commission under said Act and as may be then in effect.

IN WITNESS WHEREOF, the parties have caused their duly authorized officers
to execute this Investment Advisory Agreement as of the date and year first
above written.

JANUS CAPITAL CORPORATION

By:
Steven R. Goodbarn, Vice President

JANUS ASPEN SERIES

By:
Thomas H. Bailey

Exhibit 4(i)

JANUS ASPEN SERIES

INVESTMENT ADVISORY AGREEMENT

GLOBAL TECHNOLOGY PORTFOLIO

THIS INVESTMENT ADVISORY AGREEMENT (the "Agreement") is made this __ th day
of _________ , 1999, between JANUS ASPEN SERIES, a Delaware business trust (the
"Trust"), and JANUS CAPITAL CORPORATION, a Colorado corporation ("JCC").

W I T N E S S E T H:

WHEREAS, the Trust and JCC deem it mutually advantageous that JCC should
assist the Trustees and officers of the Trust in the management of the
securities portfolio of the Fund.

NOW, THEREFORE, the parties agree as follows:

2. Other Services. JCC is hereby authorized (to the extent the Trust has
not otherwise contracted) but not obligated (to the extent it so notifies the
Trustees at least 60 days in advance), to perform (or arrange for the
performance by affiliates of) the management and administrative services
necessary for the operation of the Fund. JCC is specifically authorized, on
behalf of the Trust, to conduct relations with custodians, depositories,
transfer and pricing agents, accountants, attorneys, underwriters, brokers and
dealers, corporate fiduciaries, insurance company separate

<PAGE>

accounts, insurers, banks and such other persons in any such other capacity
deemed by JCC to be necessary or desirable. JCC shall generally monitor and
report to Fund officers the Fund's compliance with investment policies and
restrictions as set forth in the currently effective prospectus and statement of
additional information relating to the shares of the Fund under the Securities
Act of 1933, as amended. JCC shall make reports to the Trustees of its
performance of services hereunder upon request therefor and furnish advice and
recommendations with respect to such other aspects of the business and affairs
of the Fund as it shall determine to be desirable. JCC is also authorized,
subject to review by the Trustees, to furnish such other services as JCC shall
from time to time determine to be necessary or useful to perform the services
contemplated by this Agreement.

3. Obligations of Trust. The Trust shall have the following obligations
under this Agreement:

(a) to keep JCC continuously and fully informed as to the composition
of its investment portfolio and the nature of all of its assets
and liabilities from time to time;

(c) to furnish JCC with any further materials or information which
JCC may reasonably request to enable it to perform its function
under this Agreement; and

(d) to compensate JCC for its services and reimburse JCC for its
expenses incurred hereunder in accordance with the provisions
hereof.

(a) Reasonable compensation, fees and related expenses of the Trust's
officers and its Trustees, except for such Trustees who are not
interested persons of JCC;

(b) Rental of offices of the Trust; and

<PAGE>

by JCC at any time, without penalty, by giving sixty (60) days advance written
notice of termination to the Trust, addressed to its principal place of
business. The Trust agrees that, consistent with the terms of the Trust
Instrument, the Trust shall cease to use the name "Janus" in connection with the
Fund as soon as reasonably practicable following any termination of this
Agreement if JCC does not continue to provide investment advice to the Fund
after such termination.

9. Assignment. This Agreement shall terminate automatically in the event of
any assignment of this Agreement.

14. Limitation of Liability of JCC. JCC shall not be liable for any error
of judgment or mistake of law or for any loss arising out of any investment or
for any act or omission taken with respect to the Trust, except for willful
misfeasance, bad faith or gross negligence in the performance of its duties, or
by reason of reckless disregard of its obligations and duties hereunder and
except to the extent otherwise provided by law. As used in this Section 15,
"JCC" shall include any affiliate of JCC performing services for the Trust
contemplated hereunder and directors, officers and employees of JCC and such
affiliates.

<PAGE>

IN WITNESS WHEREOF, the parties have caused their duly authorized officers
to execute this Investment Advisory Agreement as of the date and year first
above written.

JANUS CAPITAL CORPORATION

By:
Steven R. Goodbarn, Vice President

JANUS ASPEN SERIES

By:
Thomas H. Bailey, President

Exhibit 9(j)
JANUS
100 FILLMORE STREET
DENVER, COLORADO 80206-4928
PH: 303-333-3863
http://www.janus.com

October 26, 1999

Janus Aspen Series
100 Fillmore Street
Denver, Colorado 80206-4928

Re: Public Offering of Janus Aspen Series Global Technology Portfolio and
Global Life Sciences Portfolio

Gentlemen:

I have acted as counsel for Janus Aspen Series, a Delaware business trust (the
"Trust"), in connection with the filing with the Securities and Exchange
Commission of a registration statement with respect to the proposed sale of
shares of beneficial interest, $0.001 par value of the Institutional Shares and
Service Shares (the "Shares"), as separate classes of shares of the Global
Technology Portfolio and Global Life Sciences Portfolio ("Portfolios"), two new
series of the Trust.

I have examined the Trust Instrument and Bylaws, as amended, the proceedings of
the Trust's trustees relating to the authorization, issuance and proposed sale
of the Shares of the Portfolios, and such other records and documents as I have
deemed relevant. Based upon such examination, it is my opinion that upon the
issuance and sale of the Shares of the Portfolios in the manner contemplated by
the aforesaid registration statement, such Shares will be legally issued, fully
paid and nonassessable.

I hereby consent to the filing of this opinion as an exhibit to the
above-referenced registration statement. This opinion is for the exclusive use
of Janus Aspen Series in connection with the filing of such registration
statement with the Securities and Exchange Commission and is not to be used,
circulated, quoted, relied upon or otherwise referred to by any other person or
for any other purpose. This opinion is given as of the date hereof and I render
no opinion and disclaim any obligation to revise or supplement this opinion
based upon any change in applicable law or any factual matter that occurs or
comes to my attention after the date hereof.

Very truly yours,

/s/Thomas A. Early
Thomas A. Early
Vice President and General Counsel

/djw

EXHIBIT 10

CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the incorporation by reference in the Prospectuses and
Statements of Additional Information constituting parts of this Post-Effective
Amendment No. 21 to the registration statement on N-1A (the "Registration
Statement") of our report dated February 3, 1999, relating to the financial
statements and financial highlights appearing in the December 31, 1998 Annual
Report to Shareholders of Janus Aspen Series, which is also incorporated by
reference into the Registration Statement. We also consent to the reference to
us under the heading "Independent Accountants" in the Statements of Additional
Information.

/s/PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP

Denver, Colorado
October 29, 1999