INHALE THERAPEUTIC SYSTEMS
10-Q, 1996-11-14
PHARMACEUTICAL PREPARATIONS
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<PAGE>


                                    UNITED STATES 
                          SECURITIES AND EXCHANGE COMMISSION
                                WASHINGTON,  DC  20549
                                           
                                      FORM 10-Q

[X]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934.

For the quarterly period ended September 30, 1996
                                         or,
[ ]  TRANSITION REPORTS PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
     EXCHANGE ACT OF 1934.

For the transition period from                    to                     .
                              -------------------   ---------------------

                           COMMISSION FILE NUMBER: 0-23556

                              INHALE THERAPEUTIC SYSTEMS
                (Exact name of registrant as specified in its charter)

           CALIFORNIA                                   94-3134940
- ---------------------------------                  ---------------------
(State of other jurisdiction of                        (IRS Employer
 incorporation or organization)                      Identification No.)

                               1060 EAST MEADOW CIRCLE
                            PALO ALTO,  CALIFORNIA  94303
                       (Address of principal executive offices)

                                     415-354-0700
                 (Registrant's telephone number, including area code)

                                    Not applicable
- -------------------------------------------------------------------------------
                 (Former name, former address and former fiscal year,
                            if changed since last report)
                                           

Indicate by check mark whether the registrant (1) has filed all reports 
required by Section 13 or 15(d) of the Securities Exchange Act of 1934 during 
the preceding 12 months (or for such shorter period that the registrant was 
required to file such reports), and (2) has been subject to such filing 
requirements for the past 90 days. [X] Yes        [  ]  No

                         APPLICABLE ONLY TO CORPORATE ISSUERS

The number of outstanding shares of the registrant's Common Stock, no par 
value, was 11,821,472 as of November 11, 1996.


                                                                   Page 1 of 12


<PAGE>

                              INHALE THERAPEUTIC SYSTEMS
                                        INDEX



PART I: FINANCIAL INFORMATION
- -----------------------------
                                                                            PAGE

Item 1.   Condensed Financial Statements - unaudited . . . . . . . . . . . . . 3

          Condensed Balance Sheets - September 30, 1996 and December 31, 1995. 3

          Condensed Statements of Operations for the three month and
            nine month periods ended September 30, 1996 and 1995 . . . . . . . 4

          Condensed Statements of Cash Flows for the nine months
            ended September 30, 1996 and 1995. . . . . . . . . . . . . . . . . 5

          Notes to Condensed Financial Statements. . . . . . . . . . . . . . . 6

Item 2.   Management's Discussion and Analysis of Financial Condition and 
            Result of Operations . . . . . . . . . . . . . . . . . . . . . . . 7



PART II:  OTHER INFORMATION
- ---------------------------

Item 1.   Legal Proceedings. . . . . . . . . . . . . . . . . . . . . . . . . .11

Item 2.   Changes in Securities. . . . . . . . . . . . . . . . . . . . . . . .11

Item 3.   Defaults Upon Senior Securities. . . . . . . . . . . . . . . . . . .11

Item 4.   Submission of Matters to a Vote of Security Holders. . . . . . . . .11

Item 5.   Other Information. . . . . . . . . . . . . . . . . . . . . . . . . .11

Item 6.   Exhibits and Reports on Form 8-K . . . . . . . . . . . . . . . . . .11

          Signatures . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12


                                                                   Page 2 of 12

<PAGE>

Item 1.
                              INHALE THERAPEUTIC SYSTEMS

                               Condensed Balance Sheets
                                    (in thousands)
<TABLE>
<CAPTION>

                                               September 30, 1996    December 31, 1995
                                               ------------------    -----------------
                                                   (unaudited)
<S>                                            <C>                   <C>
                                        ASSETS

Current assets:
   Cash and cash equivalents                        $    8,631             $  3,834
   Short-term investments                               22,409               16,093
   Other current assets                                  2,103                  487
                                                    ----------             --------
      Total current assets                              33,143               20,414

Property and equipment, net                              3,488                2,660
Deposits and other assets                                  202                  174
                                                    ----------             --------
                                                    $   36,833             $ 23,248
                                                    ----------             --------
                                                    ----------             --------

                         LIABILITIES AND SHAREHOLDERS' EQUITY

Current liabilities:
   Accounts payable and accrued liabilities         $    1,524             $  1,616
   Accrued compensation                                    464                  519
   Deferred revenue - current portion                    1,358                  578
                                                    ----------             --------
      Total current liabilities                          3,346                2,713

Equipment financing obligations                            231                  353

Shareholders' equity:
   Common stock, no par value: 30,000
   shares authorized, 11,545 shares and
   10,142 shares issued and outstanding at 
   September 30, 1996 and December 31, 1995, 
   respectively.                                        57,794               38,202
   Deferred compensation                                  (129)                (250)
   Accumulated deficit                                 (24,409)             (17,770)
                                                    ----------             --------

      Total shareholders' equity                        33,256               20,182
                                                    ----------             --------
                                                    $   36,833             $ 23,248
                                                    ----------             --------
                                                    ----------             --------
</TABLE>

Note:  The balance sheet at December 31, 1995 has been derived from the audited
       financial statements at that date but does not include all of the
       information and footnotes required by generally accepted accounting
       principles for complete financial statements.

SEE ACCOMPANYING NOTES.


                                                                   Page 3 of 12

<PAGE>

                              INHALE THERAPEUTIC SYSTEMS

                          Condensed Statements of Operations
                     (in thousands, except per share information) 
                                     (unaudited) 



<TABLE>
<CAPTION>

                                                  Three Months Ended     Nine Months Ended
                                                      September 30,         September 30,
                                                      -------------         -------------

                                                     1996       1995       1996       1995
                                                     ----       ----       ----       ----
<S>                                                <C>        <C>        <C>        <C>
Contract research revenue                          $ 1,791    $ 1,010    $ 4,722    $ 2,619

Operating costs and expenses:
   Research and development                          3,697      2,335     10,129      6,471
   General and administrative                          784        650      2,341      2,445
                                                   -------    -------    -------    -------

   Total operating costs and expenses                4,481      2,985     12,470      8,916
                                                   -------    -------    -------    -------
Loss from operations                                (2,690)    (1,975)    (7,748)    (6,297)

Interest income, net                                   437        320      1,109        882
                                                   -------    -------    -------    -------

Net loss                                           $(2,253)   $(1,655)   $(6,639)   $(5,415)
                                                   -------    -------    -------    -------
                                                   -------    -------    -------    -------

Net loss per share                                 $ (0.20)   $ (0.16)   $ (0.58)   $ (0.56)
                                                   -------    -------    -------    -------
                                                   -------    -------    -------    -------

Shares used in computing net loss per share         11,538     10,124     11,463      9,739
                                                   -------    -------    -------    -------
                                                   -------    -------    -------    -------

</TABLE>


SEE ACCOMPANYING NOTES.


                                                                   Page 4 of 12


<PAGE>

                              INHALE THERAPEUTIC SYSTEMS

                          Condensed Statements of Cash Flows
                   Increase/(Decrease) in Cash and Cash Equivalents
                                    (in thousands)
                                     (unaudited)





                                                             Nine Months Ended
                                                               September 30,
                                                               -------------

                                                              1996       1995
                                                              ----       ----

CASH FLOWS FROM OPERATING ACTIVITIES:
   Cash used in operations                                 $ (6,670)  $ (3,793)

CASH FLOWS FROM INVESTING ACTIVITIES:

   Purchases of available for sale securities               (39,118)   (38,691)
   Sales of available for sale securities                     2,020      5,865
   Maturities of available for sale securities               30,782     18,103
   Purchases of property and equipment, net                  (1,608)      (938)
                                                           --------   --------

Net cash used in investing activities                        (7,924)   (15,661)


CASH FLOWS FROM FINANCING ACTIVITIES:
   Payments of equipment financing obligations                 (201)      (164)
   Issuance of common stock, net of issuance costs           19,592     12,247
                                                           --------   --------

   Net cash provided by financing activities                 19,391     12,083
                                                           --------   --------

   Net increase/(decrease) in cash and cash equivalents       4,797     (7,371)

Cash and cash equivalents at beginning of period              3,834     10,510
                                                           --------   --------

Cash and cash equivalents at end of period                 $  8,631     $3,139
                                                           --------   --------
                                                           --------   --------


SEE ACCOMPANYING NOTES.


                                                                  Page 5 of 12

<PAGE>

                              INHALE THERAPEUTIC SYSTEMS

                       NOTES TO CONDENSED FINANCIAL STATEMENTS
                                  September 30,1996
                                      (unaudited)

1.  BASIS OF PRESENTATION

      The accompanying unaudited condensed financial statements of Inhale 
Therapeutic Systems ("Inhale" or the "Company") have been prepared in 
accordance with generally accepted accounting principles for interim 
financial information and with the instructions for Form 10-Q and Article 10 
of Regulation S-X.  The balance sheet as of September 30, 1996, the related 
statements of operations for the three and nine month periods ended September 
30, 1996 and 1995 and cash flows for the nine month period ended September 
30, 1996 and 1995, are unaudited but include all adjustments (consisting of 
normal recurring adjustments) which the Company considers necessary for a 
fair presentation of the financial position at such dates and the operating 
results and cash flows for those periods.  Although the Company believes that 
the disclosures in these financial statements are adequate to make the 
information presented not misleading, certain information normally included 
in financial statements and related footnotes prepared in accordance with 
generally accepted accounting principles have been condensed or omitted 
pursuant to the rules and regulations of the Securities and Exchange 
Commission (the "Commission").  The accompanying financial statements should 
be read in conjunction with the financial statements and notes thereto 
included in the Company's Annual Report on Form 10-K for the year ended 
December 31, 1995 filed with the Commission.

      Results for any interim period are not necessarily indicative of 
results for any other interim period or for the entire year.

2. REVENUE RECOGNITION

      Contract revenue from collaborative research agreements is recorded 
when earned and as the related costs are incurred.  Payments received which 
are related to future performance are deferred and recognized as revenue when 
earned over future performance periods.  In accordance with contract terms, 
up-front and milestone payments from collaborative research agreements are 
considered reimbursements for costs incurred under the agreements, and 
accordingly, are generally recognized based on actual efforts expended over 
the terms of the agreements.  The Company's research revenue is derived 
primarily from partners in the pharmaceutical and biotechnology industries.  
All of the Company's research and development agreements are generally 
cancelable by the partner without significant penalty to the partner.


                                                                  Page 6 of 12


<PAGE>

      Contract research revenue from three partners represented 77%, 11% and 
10%, respectively, of the Company's revenue in the nine month period ended 
September 30, 1996.  Contract revenue from two partners accounted for 74% and 
15% of the Company's revenue in the same period last year.  Costs of contract 
research revenue approximate such revenue and are included in research and 
development expenses.

3. NET LOSS PER SHARE

      Net loss per share is computed using the weighted average number of 
shares of Common Stock outstanding.  Common equivalent shares from stock 
options and a warrant are excluded from the computation as their effect is 
antidilutive.

4. SUBSEQUENT EVENTS

      On October 23, 1996 the Company signed a lease agreement for a third 
building of approximately 121,000 square feet. The lease has a fifteen year 
term. In connection with the lease agreement, the Company issued to the 
landlord warrants to purchase 20,000 shares of the Company's common stock, 
which are exercisable if the landlord provides the Company with financing of 
up to $5 million for leasehold improvements.

      On October 24, 1996 the Company received a second $5 million equity 
investment from Pfizer Inc. ("Pfizer") pursuant to a stock purchase agreement 
between the Company and Pfizer dated January 18, 1995. This investment was 
made at a 25% premium to the market price of the Company common stock. The 
first $5 million equity investment made by Pfizer on February 28, 1995 also 
was made at a 25% premium to the market price of the Company's common stock. 
These equity investments were made in conjunction with a collaborative 
agreement between the Company and Pfizer to collaborate on the development of 
insulin products using Inhale's non-invasive pulmonary drug delivery system.

Item 2.

      MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
                              RESULTS OF OPERATIONS

      This Management's Discussion and Analysis of Financial Condition 
and Results of Operations for the three and nine months ended September 
30, 1996 and 1995, should be read in conjunction with the Management's 
Discussion and Analysis of Financial Condition and Results of Operations 
included in the Company's Annual Report on Form 10-K for the year ended 
December 31, 1995. The following discussion contains forward-looking 
statements that involve risk and uncertainties. The Company's actual 
results could differ materially from those discussed here. Factors that 
could cause or contribute to such differences include, but are not 
limited to those discussed herein, as well as those discussed under the 
heading "Risk Factors" in the Company's Annual Report on Form 10-K for 
the year ended December 31, 1995. Readers are cautioned not to place 
undue reliance on these forward-looking statements, which reflect 
management's analysis only as of the date hereof.  The Company 
undertakes no obligation to publicly release the results of any revision 
to these forward-looking statements 

                                                                  Page 7 of 12

<PAGE>

which may be made to reflect events or circumstances occuring after the date 
hereof or to reflect the occurance of unanticipated events.

OVERVIEW

      Since its inception in July 1990, Inhale has been engaged in the 
development of a pulmonary system for the delivery of macromolecule drugs for 
systemic and local lung applications.  The Company has been unprofitable 
since inception and expects to incur significant and increasing additional 
operating losses over the next several years primarily due to increasing 
research and development expenditures and expansion of late stage clinical 
and early stage commercial manufacturing facilities.  To date, Inhale has not 
sold any products and does not anticipate receiving revenue from product 
sales or royalties in the near future.  For the period from inception through 
September 30, 1996, the Company incurred a cumulative net loss of 
approximately $24.4 million.  Inhale's sources of working capital have been 
equity financing, financing of equipment acquisitions, interest  earned on 
investments of cash, and revenues from short-term research and feasibility 
agreements and development contracts.

      Inhale typically has been compensated for research and development 
expenses during initial feasibility work performed under collaborative 
arrangements. Inhale's strategy is to enter into development contracts with 
pharmaceutical and biotechnology corporate partners after feasibility is 
demonstrated. Partners that enter into collaborative agreements will pay for 
research and development expenses and may make payments to Inhale as it 
achieves certain key milestones. Inhale expects to receive royalties from its 
partners based on revenues received from product sales, and to receive 
revenue from the manufacturing of powders and the supply of devices.  To 
date, one up-front signing payment and two milestone and no royalty payments 
have been received by the Company under its collaborative agreements.  In 
certain cases, the Company may enter into collaborative agreements under 
which the Company's partners would manufacture or package powders or supply 
inhalation devices, thereby potentially limiting one or more sources of 
revenue for the Company.  To achieve and sustain profitable operations, the 
Company, alone or with others, must successfully develop, obtain regulatory 
approval for, manufacture, introduce, market and sell products utilizing its 
pulmonary drug delivery system.  There can be no assurance that the Company 
can generate sufficient product or contract research revenue to become 
profitable or to sustain profitability.

RESULTS OF OPERATIONS

      Revenues in the third quarter of 1996 were $1,791,000, as compared to 
$1,010,000 in the third quarter of 1995, an increase of 77%.  Revenues for 
the nine months ended September 30, 1996 were $4,722,000, as compared to 
$2,619,000 for the nine months ended September 30, 1995, an increase of 80%.  
The increase in revenues was primarily due to revenue recognized under the 
Company's collaborative agreement entered into with Pfizer, Inc. ("Pfizer") 
on January 18, 1995.  Such revenue was comprised of reimbursed research and 
development expenses and the amortization of the pro-rata portion of the 
up-front signing and milestone payments based on actual efforts expended.  
The collaboration covers the development of insulin products using Inhale's 
non-invasive pulmonary drug delivery system for macromolecules.  Costs of 
contract

                                                                  Page 8 of 12

<PAGE>

research revenue approximate such revenue and are included in research and 
development expense.

      Research and development expenses increased to approximately $3,697,000 
in the third quarter of 1996 from $2,335,000 in the third quarter of 1995, an 
increase of 58%.  Research and development expenses for the nine months ended 
September 30, 1996 increased to $10,129,000 from $6,471,000 for the nine 
months ended September 30, 1995, an increase of 57%.  The increase is 
primarily attributed to continued expansion of research activities resulting 
from an increase in the number of projects, additional hiring of scientific 
personnel, and increased costs of laboratory supplies and consulting 
services.  The Company expects research, development and process development 
spending to increase significantly over the next few years as the Company 
continues to expand its research and development and commence its early stage
manufacturing efforts.

      General and administrative expenses increased to $784,000 in the third 
quarter of 1996 from $650,000 in the third quarter of 1995, an increase of 
21%. General and administrative expenses for the nine months ended September 
30, 1996 were $2,341,000, as compared to $2,445,000 for the nine months ended 
September 30, 1995, a decrease of 4%.  The decrease in the first nine months 
of 1996 was due primarily to the marketing consulting costs associated with 
the Company's collaborative agreements that were incurred in the first 
quarter of 1995 but not experienced at the same level in the same period this 
year. General and administrative expenses are expected to continue to 
increase to support increased levels of research, development and 
manufacturing activities and to cover the costs of being a public company.

      Net interest income increased to $437,000 in the third quarter of 1996 
compared to $320,000 in the third quarter of 1995.  Net interest income 
increased to $1,109,000 for the nine months ended September 30, 1996 from 
$882,000 for the nine months ended September 30, 1995, an increase of 26%. 
Interest income was earned on larger cash and investment balances held by the 
Company in the three and nine month periods ended September 30, 1996, 
compared to the same periods last year.  The higher cash balance is a result 
of the $20.0 million equity investment made by Baxter on April 9, 1996.

LIQUIDITY AND CAPITAL RESOURCES

      The Company has financed its operations primarily through private 
placements of its equity securities, public offerings, contract research 
revenues, interest income earned on its investments of cash and financing of 
equipment acquisitions. On April 9, 1996, Baxter Healthcare Corporation 
("Baxter") made a $20.0 million equity investment in Inhale at a 25% premium 
to market price in conjunction with an agreement the Company signed with 
Baxter in March 1996 to develop products using Inhale's non-invasive 
pulmonary drug delivery system for macromolecules. At September 1996, the 
Company had cash, cash equivalents and short-term investments of 
approximately $31.0 million.

      The Company's operations used cash of $6.7 million in the nine months 
ended September 30, 1996, as compared to $3.8 million for the nine months 
ended September 30, 1995. The increase in cash usage was due to increased 
operating expenses in the nine month period ended September 30, 1996 as 
compared to the same period last year. These amounts differed from the


                                                                   Page 9 of 12
<PAGE>

Company's net operating losses in these periods due principally to 
depreciation expenses, and increases in accounts payable and accrued 
liabilities. 

      The Company expects its cash requirements to increase due to expected 
increases in expenses related to the further research and development of its 
technologies resulting from a larger number of projects, development of drug 
formulations, process development for the manufacture and filling of powders 
and devices, marketing, and general and administrative costs.  These expenses 
include, but are not limited to, increases in personnel and personnel related 
costs, capital equipment, inhalation device prototype construction and 
facilities expansion, including the planning and building of a late-stage 
clinical and early-stage commercial manufacturing facility.

      The Company believes that its cash, cash equivalents and short-term 
investments as of September 30, 1996 of approximately $31.0 million, together 
with the: i) $5.0 million equity investment made by Pfizer on October 24, 
1996; and ii) interest income and possible additional equipment financing, 
will be sufficient to meet its operating expense and capital expenditure 
requirements at least through 1997.  However, the Company's capital needs 
will depend on many factors, including continued scientific progress in its 
research and development arrangements, progress with pre-clinical and 
clinical trials, the time and costs involved in obtaining regulatory 
approvals, the costs of developing and the rate of scale-up of the Company's 
powder processing and packaging technologies, the timing and cost of its 
late-stage clinical and early commercial production facility, the costs 
involved in preparing, filing, prosecuting, maintaining and enforcing patent 
claims, the need to acquire licenses to new technologies and the status of 
competitive products.  To satisfy its long-term needs, the Company intends to 
seek additional funding, as necessary, from corporate partners and from the 
sale of securities.  There can be no assurance that additional funds, if and 
when required, will be available to the Company on favorable terms, if at all.



PART II:  OTHER INFORMATION
- ---------------------------


Item 1.   Legal Proceedings  -  None

Item 2.   Changes in Securities  -  None

Item 3.   Defaults upon Senior Securities  -  None

Item 4.   Submission of Matters to a Vote of Security Holders  -  None

Item 5.   Other Information  -  None


                                                                 Page 10 of 12

<PAGE>

Item 6.   Exhibits and Reports on Form 8-K

          (a)  Exhibits

          The following exhibits are filed herewith or incorporated by reference
<TABLE>
<CAPTION>

  EXHIBIT                                          EXHIBIT TITLE
- ------------------------------------------------------------------------------------------
<S>         <C>
 3.1(3)     Restated Articles of Incorporation of the Registrant.
 3.2(1)     Bylaws of the Registrant.
 4.1        Reference is made to Exhibits 3.1 through 3.2.
 4.2(1)     Restated Investor Rights Agreement among the Registrant and certain other
            persons named therein, dated April 29, 1993, as amended October 29, 1993.
 4.3(1)     Stock Purchase Agreement between the Registrant and Robert M. Platz, dated
            August 2, 1990.
 4.4(1)     Stock Purchase Agreement between the Registrant and John S. Patton, dated
            August 2, 1990.
 4.5(1)     Warrant to purchase 18,182 Shares of Series C Preferred Stock between the
            Registrant and Phoenix Leasing Incorporated, dated October 29, 1993.
 4.6(1)     Specimen stock certificate.
 4.7(1)     Stock Restriction Agreement between the Registrant and Robert M. Platz, dated
            September 13, 1991.
 4.8(1)     Stock Restriction Agreement between the Registrant and John S. Patton, dated
            September 13, 1991.
 4.9(2)     Stock Purchase Agreement between the Registrant and Pfizer Inc., dated
            January 18, 1995.
 4.10       Warrant to Purchase 10,000 shares of Common Stock between the Registrant and
            Thomas J. Peirona, dated November 1, 1996.
 4.11       Warrant to Purchase 10,000 shares of Common Stock between the Registrant and
            Kiet Nguyen, dated November 1, 1996.
 10.1(4)    Registrant's 1994 Equity Incentive Plan, as amended (the Equity Incentive Plan).
 10.2(1)    Form of Incentive Stock Option under the Equity Incentive Plan.
 10.3(1)    Form of Nonstatutory Stock Option under the Equity Incentive Plan.
 10.4(7)    Registrant's 1994 Non-Employee Directors' Stock Option Plan, as amended.
 10.5(1)    Registrant's 1994 Employee Stock Purchase Plan.
 10.6(1)    Standard Industrial Lease between the Registrant and W.F. Batton & Co., Inc.,
            dated September 17, 1992, as amended September 18, 1992.
 10.7(1)    Master Equipment Lease between the Registrant and Phoenix Leasing Incorporated,
            dated August 15, 1992 and Schedules i to 4 thereto.
 10.8(1)    Senior Loan and Security Agreement between the Registrant and Phoenix Leasing
            Incorporated, dated September 15, 1993.
 10.9(1)    Sublicense Agreement between the Registrant and John S. Patton, dated
            September 13, 1991.
 10.10(2)   Offer Letter, dated September 16, 1994, from the Registrant to Jack M. Anthony.
 10.11(2)   Addendum to Lease dated September 17, 1992, between the Registrant and W.F. Batton &
            Marie A. Batton.
 10.12(6)   Lease dated May 31, 1995, between the Registrant and W.F. Batton &
            Marie A. Batton.
 10.13(6)   Addendum Number One to Lease dated September 17, 1992, between the Registrant
            and W.F. Batton & Marie A. Batton.
 10.14(6)   Addendum to Lease dated May 31, 1995 between the Registrant and W.F. Batton &
            Marie A. Batton.
 10.15(6)   Addendum Number Two to Lease dated September 17, 1992, between the Registrant
            and W.F. Batton & Marie A. Batton.
 10.16(5)   Stock Purchase Agreement between the Registrant and Baxter World Trade
            Corporation, dated March 1, 1996.
 10.17      Sublease and Lease Agreement, dated October 2, 1996, between the 
            Registrant and T.M.T. Associates L.L.C.
 27.1       Financial Data Schedule

</TABLE>
                                                                  Page 11 of 12
<PAGE>

___________

(1)  Incorporated by reference to the indicated exhibit in the Company's
     Registration Statement (No. 33-75942), as amended.
(2)  Incorporated by reference to the indicated exhibit in the Company's
     Registration Statement (No. 33-89502), as amended.
(3)  Incorporated by reference to the indicated exhibit in the Company's Annual
     Report on Form 10-K for  the year ended December 31, 1994.
(4)  Incorporated by reference to the Company's Registration Statement on
     Form S-8 (No. 333-07969).
(5)  Incorporated by reference to the indicated exhibit in the Company's 
     Quarterly Report on Form 10-Q for the quarter ended March 31, 1996.
(6)  Incorporated by reference to the indicated exhibit in the Company's Annual 
     Report on Form 10-K for the year ended December 31, 1995.
(7)  Incorporated by reference to the indicated exhibit in the Company's
     Quarterly Report on Form 10-Q for the quarter ended June 30, 1996.

         (b)  No reports on Form 8-K were filed during the quarter ended
September 30, 1996

Pursuant to the requirements of the Securities Exchange Act of 1934, the 
registrant has duly caused this report to be signed on its behalf by the 
undersigned thereunto.


                                            INHALE THERAPEUTIC SYSTEMS




DATE: November 14, 1996                          BY: /S/Robert B. Chess
                                                 ------------------------------
                                                 Robert  B. Chess
                                                 President, Chief Executive
                                                 Officer and Director




DATE: November 14, 1996                          BY: /S/Judi R. Lum
                                                 ------------------------------
                                                 Judi R. Lum
                                                 Chief Financial Officer


                                                                  Page 12 of 12


<PAGE>


                                                             WARRANT NO. CSW-1

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED FOR 
INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR 
ANY STATE SECURITIES LAWS.  SUCH SECURITIES MAY NOT BE SOLD OR TRANSFERRED IN 
THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SAID ACT AND 
ANY APPLICABLE STATE SECURITIES LAWS.

                          WARRANT TO PURCHASE 10,000 SHARES
                                 OF COMMON STOCK OF 
                              INHALE THERAPEUTIC SYSTEMS
                             (VOID AFTER OCTOBER 1, 2006)


    This certifies that Thomas J. Peirona or his assigns (the "Holder"), for 
value received, is entitled to purchase from Inhale Therapeutic Systems, a 
California corporation (the "Company"), having a place of business at 1060 
East Meadow Circle, Palo Alto, California, 94303, a maximum of Ten Thousand 
(10,000) fully paid and nonassessable shares of the Company's Common Stock 
for cash at a price of $13.125 per share (the "Stock Purchase Price") at any 
time or from time to time after the satisfaction of the conditions set forth 
in Section 1.1 below and until 5:00 p.m. (Pacific time) on October 1, 2006 
(the "Expiration Date"), upon surrender to the Company at its principal 
office (or at such other location as the Company may advise the Holder in 
writing) of this Warrant properly endorsed with the Form of Subscription 
attached hereto duly filled in and signed and, if applicable, upon payment in 
cash or by check of the aggregate Stock Purchase Price for the number of 
shares for which this Warrant is being exercised determined in accordance 
with the provisions hereof.  The Stock Purchase Price and the number of 
shares purchasable hereunder are subject to adjustment as provided in Section 
3 of this Warrant.

    This Warrant is subject to the following terms and conditions:

1.  Exercise; Issuance of Certificates; Payment for Shares.

    1.1  EXERCISABILITY.  This Warrant shall not be exercisable until such time
as T.M.T. Associates LLC ("Landlord") has completed one of the following two
conditions:  (a)  Landlord shall have closed the Tenant Improvement Loan
referred to in Section 3.1 of that certain Lease Agreement, dated October 2,
1996, by and between the Company and Landlord (the "Lease") and shall have
disbursed proceeds from such Tenant Improvement Loan of at least $5,000,000 to
the Company; or (b) in the event the Company waives Landlord's obligation to
procure the Tenant Improvement Loan under the Lease, Landlord shall have
procured a written loan commitment on the terms and conditions described in
Section 3.1(c) of the Lease from a lender meeting the qualifications set forth
in Section 3.1(c) of the Lease.  Upon the completion of one of the two
conditions set forth in the preceding sentence prior to the Expiration Date,
this Warrant shall be exercisable upon the terms and conditions set forth
herein.  If neither of the two


                                     1

<PAGE>

conditions is satisfied prior to the Expiration Date, this Warrant shall not 
become exercisable and shall expire and be of no further force or effect.

    1.2. GENERAL.  Subject to the requirements of Section 1.1 above, this 
Warrant is exercisable at the option of the holder of record hereof up to the 
Expiration Date for all or any part of the shares of Common Stock (but not 
for a fraction of a share) which may be purchased hereunder.  The Company 
agrees that the shares of Common Stock purchased under this Warrant shall be 
and are deemed to be issued to the Holder hereof as the record owner of such 
shares as of the close of business on the date on which this Warrant shall 
have been surrendered, properly endorsed, the completed, executed Form of 
Subscription delivered and payment made for such shares.  Certificates for 
the shares of Common Stock so purchased, together with any other securities 
or property to which the Holder hereof is entitled upon such exercise, shall 
be delivered to the Holder hereof by the Company at the Company's expense 
within a reasonable time after the rights represented by this Warrant have 
been so exercised.  In case of a purchase of less than all the shares which 
may be purchased under this Warrant, the Company shall cancel this Warrant 
and execute and deliver a new Warrant or Warrants of like tenor for the 
balance of the shares purchasable under the Warrant surrendered upon such 
purchase to the Holder hereof within a reasonable time.  Each stock 
certificate so delivered shall be in such denominations of Common Stock as 
may be requested by the Holder hereof and shall be registered in the name of 
such Holder. 

    1.3. NET ISSUE EXERCISE.  Notwithstanding any provisions herein to the 
contrary, if the fair market value of one share of the Company's Common Stock 
is greater than the Stock Purchase Price (at the date of calculation as set 
forth below), in lieu of exercising this Warrant for cash, the Holder may 
elect to receive shares equal to the value (as determined below) of this 
Warrant (or the portion thereof being canceled) by surrender of this Warrant 
at the principal office of the Company together with the properly endorsed 
Form of Subscription and notice of such election in which event the Company 
shall issue to the Holder a number of shares of Common Stock computed using 
the following formula:

              X = Y (A-B)
                  -------
                      A

         Where        X =  the number of shares of Common Stock to be issued
                      to the Holder
                      Y =  the number of shares of Common Stock purchasable
                           under the Warrant or, if only a portion of the
                           Warrant is being exercised, the portion of the
                           Warrant being canceled (at the date of such
                           calculation)
                      A =  the fair market value of one share of the Company's
                           Common Stock (at the date of such calculation)



                                     2

<PAGE>

                      B =  Stock Purchase Price (as adjusted to the date of 
                           such calculation)

For purposes of the above calculation, if the Common Stock is traded in a 
public market, the fair market value of one share of Common Stock shall be 
the average of the closing price of the Company's Common Stock reported for 
each of the five (5) business days immediately preceding the business day on 
which Holder delivers the Form of Subscription to the Company.  If the Common 
Stock is not traded in a public market, fair market value of one share of 
Common Stock shall be determined by the Company's Board of Directors in good 
faith.  The Company and the Holder agree to report any exercise under this 
Section 1.3 for federal and state income tax purposes in the following 
manner:  Holder will be treated as having excised a portion of the Warrant 
for X shares of the Company's Common Stock, and having paid the Stock 
Purchase Price due upon such exercise by surrendering to the Company another 
portion of the Warrant exercisable for a number of shares equal to Y-X, with 
such surrender portion of the Warrant valued at (Y-X)(A-B).

2.  SHARES TO BE FULLY PAID; RESERVATION OF SHARES.  The Company covenants 
and agrees that all shares of Common Stock which may be issued upon the 
exercise of the rights represented by this Warrant will, upon issuance, be 
duly authorized, validly issued, fully paid and nonassessable and free from 
all preemptive rights of any shareholder and free of all taxes, liens and 
charges with respect to the issue thereof. The Company further covenants and 
agrees that, during the period within which the rights represented by this 
Warrant may be exercised, the Company will at all times have authorized and 
reserved, for the purpose of issue or transfer upon exercise of the 
subscription rights evidenced by this Warrant, a sufficient number of shares 
of authorized but unissued Common Stock, or other securities and property, 
when and as required to provide for the exercise of the rights represented by 
this Warrant.  The Company will take all such action as may be necessary to 
assure that such shares of Common Stock may be issued as provided herein 
without violation of any applicable law or regulation, or of any requirements 
of any domestic securities exchange upon which the Common Stock may be 
listed; provided, however, that the Company shall not be required to effect a 
registration under Federal or State securities laws with respect to such 
exercise.  The Company will not take any action which would result in any 
adjustment of the Stock Purchase Price (as set forth in Section 3 hereof) if 
the total number of shares of Common Stock issuable after such action upon 
exercise of all outstanding warrants, together with all shares of Common 
Stock then outstanding and all shares of Common Stock then issuable upon 
exercise of all options and upon the conversion of all convertible securities 
then outstanding, would exceed the total number of shares of Common Stock 
then authorized by the Company's Restated Articles of Incorporation.

3.  ADJUSTMENT OF STOCK PURCHASE PRICE AND NUMBER OF SHARES.  The Stock 
Purchase Price and the number of shares purchasable upon the exercise of this 
Warrant shall be subject to adjustment from time to time upon the occurrence 
of certain events described in this Section 3.  Upon each adjustment of the 
Stock Purchase Price, the Holder of this Warrant shall thereafter be entitled 
to purchase, at the Stock Purchase Price resulting from such adjustment, the 
number of shares obtained by multiplying the Stock Purchase Price in effect 
immediately prior to such adjustment by the number of shares purchasable 
pursuant hereto immediately prior to such

                                     3

<PAGE>

adjustment, and dividing the product thereof by the Stock Purchase Price 
resulting from such adjustment.

    3.1. SUBDIVISION OR COMBINATION OF STOCK.  In case the Company shall at 
any time subdivide its outstanding shares of Common Stock into a greater 
number of shares, the Stock Purchase Price in effect immediately prior to 
such subdivision shall be proportionately reduced, and conversely, in case 
the outstanding shares of Common Stock of the Company shall be combined into 
a smaller number of shares, the Stock Purchase Price in effect immediately 
prior to such combination shall be proportionately increased.

    3.2. DIVIDENDS IN COMMON STOCK, OTHER STOCK, PROPERTY, RECLASSIFICATION.  
If at any time or from time to time the Holders of Common Stock (or any 
shares of stock or other securities at the time receivable upon the exercise 
of this Warrant) shall have received or become entitled to receive, without 
payment therefor,

         (a)  Common Stock or any shares of stock or other securities which 
are at any time directly or indirectly convertible into or exchangeable for 
Common Stock, or any rights or options to subscribe for, purchase or 
otherwise acquire any of the foregoing by way of dividend or other 
distribution,

         (b)  any cash paid or payable otherwise than as a cash dividend, or

         (c)  Common Stock or additional stock or other securities or 
property (including cash) by way of spinoff, split-up, reclassification, 
combination of shares or similar corporate rearrangement, (other than shares 
of Common Stock issued as a stock split or adjustments in respect of which 
shall be covered by the terms of Section 3.1 above), then and in each such 
case, the Holder hereof shall, upon the exercise of this Warrant, be entitled 
to receive, in addition to the number of shares of Common Stock receivable 
thereupon, and without payment of any additional consideration therefor, the 
amount of stock and other securities and property (including cash in the 
cases referred to in clause (b) above and this clause (c)) which such Holder 
would hold on the date of such exercise had he been the holder of record of 
such Common Stock as of the date on which holders of Common Stock received or 
became entitled to receive such shares or all other additional stock and 
other securities and property.

    3.3. REORGANIZATION, RECLASSIFICATION, CONSOLIDATION, MERGER OR SALE.  If 
any recapitalization, reclassification or reorganization of the capital stock 
of the Company, or any consolidation or merger of the Company with another 
corporation, or the sale of all or substantially all of its assets or other 
transaction shall be effected in such a way that holders of Common Stock 
shall be entitled to receive stock, securities, or other assets or property 
(an "Organic Change"), then, as a condition of such Organic Change, lawful 
and adequate provisions shall be made by the Company whereby the Holder 
hereof shall thereafter have the right to purchase and receive (in lieu of 
the shares of the Common Stock of the Company immediately theretofore 
purchasable and receivable upon the exercise of the rights represented 
hereby) such shares of stock, securities or other assets or property as may 
be issued or payable with respect to or in exchange for a number of 
outstanding shares of such Common Stock equal to the number of


                                     4

<PAGE>

shares of such stock immediately theretofore purchasable and receivable upon 
the exercise of the rights represented hereby; provided, however, that in the 
event the value of the stock or securities (determined in good faith by the 
Board of Directors of the Company) issuable or payable with respect to one 
share of the Common Stock of the Company immediately theretofore purchasable 
and receivable upon the exercise of the rights represented hereby is in 
excess of the Stock Purchase Price hereof effective at the time of a merger 
and the stock or securities received in such reorganization, if any, are 
publicly traded and are freely tradeable by the Holder under Rule 144 or 145 
under the Securities Act of 1933, as amended, then this Warrant shall expire 
unless exercised prior to such Organic Change.  In the event of any Organic 
Change, appropriate provision shall be made by the Company with respect to 
the rights and interests of the Holder of this Warrant to the end that the 
provisions hereof (including, without limitation, provisions for adjustments 
of the Stock Purchase Price and of the number of shares purchasable and 
receivable upon the exercise of this Warrant) shall thereafter be applicable, 
in relation to any shares of stock, securities or assets thereafter 
deliverable upon the exercise hereof.

    3.4.      CERTAIN EVENTS.  If any change in the outstanding Common Stock 
of the Company or any other event occurs as to which the other provisions of 
this Section 3 are not strictly applicable or if strictly applicable would 
not fairly protect the purchase rights of the Holder of the Warrant in 
accordance with such provisions, then the Board of Directors of the Company 
shall make an adjustment in the number and class of shares available under 
the Warrant, the Stock Purchase Price or the application of such provisions, 
so as to protect such purchase rights as aforesaid.  The adjustment shall be 
such as will give the Holder of the Warrant upon exercise for the same 
aggregate Stock Purchase Price the total number, class and kind of shares as 
he would have owned had the Warrant been exercised prior to the event and had 
he continued to hold such shares until after the event requiring adjustment.

    3.5. NOTICES OF CHANGE.

         (a)  Promptly following any adjustment in the number or class of 
shares subject to this Warrant and of the Stock Purchase Price, the Company 
shall give written notice thereof to the Holder, setting forth in reasonable 
detail and certifying the calculation of such adjustment.

         (b)  The Company shall give written notice to the Holder at least 10 
business days prior to the date on which the Company closes its books or 
takes a record for determining rights to receive any dividends or 
distributions.

         (c)  The Company shall also give written notice to the Holder at 
least 15 business days prior to the date on which an Organic Change shall 
take place.

4.  ISSUE TAX.  The issuance of certificates for shares of Common Stock upon 
the exercise of the Warrant shall be made without charge to the Holder of the 
Warrant for any issue tax (other than any applicable income taxes) in respect 
thereof; provided, however, that the Company shall not be required to pay any 
tax which may be payable in respect of any transfer involved in the


                                     5

<PAGE>

issuance and delivery of any certificate in a name other than that of the 
then Holder of the Warrant being exercised.

5.  CLOSING OF BOOKS.  The Company will at no time close its transfer books 
against the transfer of any warrant or of any shares of Common Stock issued 
or issuable upon the exercise of any warrant in any manner which interferes 
with the timely exercise of this Warrant.

6.  NO VOTING OR DIVIDEND RIGHTS; LIMITATION OF LIABILITY.  Nothing contained 
in this Warrant shall be construed as conferring upon the Holder hereof the 
right to vote or to consent or to receive notice as a shareholder of the 
Company or any other matters or any rights whatsoever as a shareholder of the 
Company.  No dividends or interest shall be payable or accrued in respect of 
this Warrant or the interest represented hereby or the shares purchasable 
hereunder until, and only to the extent that, this Warrant shall have been 
exercised.  No provisions hereof, in the absence of affirmative action by the 
holder to purchase shares of Common Stock, and no mere enumeration herein of 
the rights or privileges of the holder hereof, shall give rise to any 
liability of such Holder for the Stock Purchase Price or as a shareholder of 
the Company, whether such liability is asserted by the Company or by its 
creditors.

7.  WARRANTS TRANSFERABLE.  Subject to compliance with applicable federal and 
state securities laws, this Warrant and all rights hereunder are 
transferable, in whole or in part, without charge to the holder hereof 
(except for transfer taxes), upon surrender of this Warrant properly 
endorsed.  Each taker and holder of this Warrant, by taking or holding the 
same, consents and agrees that this Warrant, when endorsed in blank, shall be 
deemed negotiable, and that the holder hereof, when this Warrant shall have 
been so endorsed, may be treated by the Company, at the Company's option, and 
all other persons dealing with this Warrant as the absolute owner hereof for 
any purpose and as the person entitled to exercise the rights represented by 
this Warrant, or to the transfer hereof on the books of the Company any 
notice to the contrary notwithstanding; but until such transfer on such 
books, the Company may treat the registered owner hereof as the owner for all 
purposes.

8.  RIGHTS AND OBLIGATIONS SURVIVE EXERCISE OF WARRANT.  The rights and 
obligations of the Company, of the holder of this Warrant and of the holder 
of shares of Common Stock issued upon exercise of this Warrant, referred to 
in Section 7 shall survive the exercise of this Warrant.

9.  MODIFICATION AND WAIVER.  This Warrant and any provision hereof may be 
changed, waived, discharged or terminated only by an instrument in writing 
signed by the party against which enforcement of the same is sought. 

10. NOTICES.  Any notice, request or other document required or permitted to be 
given or delivered to the holder hereof or the Company shall be delivered or 
shall be sent by certified mail, postage prepaid, to each such holder at its 
address as shown on the books of the Company or to the Company at the address 
indicated therefor in the first paragraph of this Warrant or such other 
address as either may from time to time provide to the other.


                                     6

<PAGE>

11. BINDING EFFECT ON SUCCESSORS.  This Warrant shall be binding upon any 
corporation succeeding the Company by merger, consolidation or acquisition of 
all or substantially all of the Company's assets.  All of the obligations of 
the Company relating to the Common Stock issuable upon the exercise of this 
Warrant shall survive the exercise and termination of this Warrant.  All of 
the covenants and agreements of the Company shall inure to the benefit of the 
successors and assigns of the holder hereof.

12. DESCRIPTIVE HEADINGS AND GOVERNING LAW.  The description headings of the 
several sections and paragraphs of this Warrant are inserted for convenience 
only and do not constitute a part of this Warrant.  This Warrant shall be 
construed and enforced in accordance with, and the rights of the parties 
shall be governed by, the laws of the State of California. 

13. LOST WARRANTS.  The Company represents and warrants to the Holder hereof 
that upon receipt of evidence reasonably satisfactory to the Company of the 
loss, theft, destruction, or mutilation of this Warrant and, in the case of 
any such loss, theft or destruction, upon receipt of an indemnity reasonably 
satisfactory to the Company, or in the case of any such mutilation upon 
surrender and cancellation of such Warrant, the Company, at its expense, will 
make and deliver a new Warrant, of like tenor, in lieu of the lost, stolen, 
destroyed or mutilated Warrant.

14. FRACTIONAL SHARES.  No fractional shares shall be issued upon exercise of 
this Warrant.  The Company shall, in lieu of issuing any fractional share, 
pay the holder entitled to such fraction a sum in cash equal to such fraction 
multiplied by the then effective Stock Purchase Price.



                        [THIS SPACE INTENTIONALLY LEFT BLANK]



                                        7

<PAGE>



    IN WITNESS WHEREOF, the Company has caused this Warrant to be duly 
executed by its officers, thereunto duly authorized this 1st day of November, 
1996.

                                  INHALE THERAPEUTIC SYSTEMS,
                                  a California corporation


                                    /s/ Robert B. Chess
                                  -------------------------------------
                                       Robert B. Chess
                                       President

ATTEST:


/s/ Mark P. Tanoury
- -------------------------------
Mark P. Tanoury
Secretary




                                        8
<PAGE>

                               EXHIBIT A
                                           
                           SUBSCRIPTION FORM
                                           
                                                Date:  _________________, 19___

Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

/ /  The undersigned hereby elects to exercise the warrant issued to it by
     Inhale Therapeutic Systems (the "Company") and dated November
     1, 1996 Warrant No. CSW-1 (the "Warrant") and to purchase thereunder
     __________________________________ shares of the Common Stock of the
     Company (the "Shares") at a purchase price of ______________________
     Dollars ($__________) per Share or an aggregate purchase price of
     __________________________________ Dollars ($__________) (the
     "Purchase Price").

/ /  The undersigned hereby elects to convert _______________________
     percent (____%) of the value of the Warrant pursuant to the
     provisions of Section 1.3 of the Warrant.

     Pursuant to the terms of the Warrant the undersigned has delivered the 
Purchase Price herewith in full in cash or by certified check or wire 
transfer.  The undersigned also makes the representations set forth on the 
attached Exhibit B of the Warrant.

                              Very truly yours,

                              ______________________________________________

                              By:                                               
                                 ___________________________________________

                              Title:                                            
                                    ________________________________________



                                        1.

<PAGE>


                              EXHIBIT B
                                         
                      INVESTMENT REPRESENTATION
                                           
                                                Date:  _________________, 19___


Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

    The undersigned, _________________________ ("Purchaser"), intends to 
acquire up to ______________ shares of the Common Stock (the "Common Stock") 
of Inhale Therapeutic Systems (the "Company") from the Company pursuant to 
the exercise of that certain Warrant to purchase Common Stock held by 
Purchaser.  The Common Stock will be issued to Purchaser in a transaction not 
involving a public offering and pursuant to an exemption from registration 
under the Securities Act of 1933, as amended (the "1933 Act") and applicable 
state securities laws.  In connection with such purchase and in order to 
comply with the exemptions from registration relied upon by the Company, 
Purchaser represents, warrants and agrees as follows:

    Purchaser is acquiring the Common Stock for its own account, to hold for 
investment, and Purchaser shall not make any sale, transfer or other 
disposition of the Common Stock in violation of the 1933 Act or the General 
Rules and Regulations promulgated thereunder by the Securities and Exchange 
Commission (the "SEC") or in violation of any applicable state securities 
law.      

    Purchaser has been advised that the Common Stock has not been registered 
under the 1933 Act or state securities laws on the ground that this 
transaction is exempt from registration, and that reliance by the Company on 
such exemptions is predicated in part on Purchaser's representations set 
forth in this letter.

    Purchaser has been informed that under the 1933 Act, the Common Stock 
must be held indefinitely unless it is subsequently registered under the 1933 
Act or unless an exemption from such registration (such as Rule 144) is 
available with respect to any proposed transfer or disposition by Purchaser 
of the Common Stock.  Purchaser further agrees that the Company may refuse to 
permit Purchaser to sell, transfer or dispose of the Common Stock (except as 
permitted under Rule 144) unless there is in effect a registration statement 
under the 1933 Act and any applicable state securities laws covering such 
transfer, or unless Purchaser furnishes an opinion of counsel reasonably 
satisfactory to counsel for the Company, to the effect that such registration 
is not required.


                                        2.
<PAGE>


    Purchaser also understands and agrees that there will be placed on the 
certificate(s) for the Common Stock, or any substitutions therefor, a legend 
stating in substance:    

         "The shares represented by this certificate have not 
    been registered under the Securities Act of 1933, as amended
    (the "Securities Act"), or any state securities laws.
    These shares have been acquired for investment and may not be
    sold or otherwise transferred in the absence of an effective
    registration statement for these shares under the Securities
    Act and applicable state securities laws, or an opinion of 
    counsel satisfactory to the Company that registration is not
    required and that an applicable exemption is available."

    Purchaser has carefully read this letter and has discussed its 
requirements and other applicable limitations upon Purchaser's resale of the
Common Stock with Purchaser's counsel.

                                   Very truly yours,

                                   _____________________________________

                                   By:
                                      __________________________________

                                   Title:
                                         _______________________________




                                        3.


<PAGE>


                                                           WARRANT NO. CSW-2

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED FOR 
INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR 
ANY STATE SECURITIES LAWS.  SUCH SECURITIES MAY NOT BE SOLD OR TRANSFERRED IN 
THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM UNDER SAID ACT AND 
ANY APPLICABLE STATE SECURITIES LAWS.


                       WARRANT TO PURCHASE 10,000 SHARES
                              OF COMMON STOCK OF 
                           INHALE THERAPEUTIC SYSTEMS
                          (VOID AFTER OCTOBER 1, 2006)


    This certifies that Kiet Nguyen or his assigns (the "Holder"), for value
received, is entitled to purchase from Inhale Therapeutic Systems, a California
corporation (the "Company"), having a place of business at 1060 East Meadow
Circle, Palo Alto, California, 94303, a maximum of Ten Thousand (10,000) fully
paid and nonassessable shares of the Company's Common Stock for cash at a price
of $13.125 per share (the "Stock Purchase Price") at any time or from time to
time after the satisfaction of the conditions set forth in Section 1.1 below 
and until 5:00 p.m. (Pacific time) on October 1, 2006 (the "Expiration Date"), 
upon surrender to the Company at its principal office (or at such other 
location as the Company may advise the Holder in writing) of this Warrant 
properly endorsed with the Form of Subscription attached hereto duly filled in 
and signed and, if applicable, upon payment in cash or by check of the 
aggregate Stock Purchase Price for the number of shares for which this Warrant 
is being exercised determined in accordance with the provisions hereof.  The 
Stock Purchase Price and the number of shares purchasable hereunder are subject 
to adjustment as provided in Section 3 of this Warrant.

    This Warrant is subject to the following terms and conditions:

1.  Exercise; Issuance of Certificates; Payment for Shares.

    1.1  EXERCISABILITY.  This Warrant shall not be exercisable until such time
as T.M.T. Associates LLC ("Landlord") has completed one of the following two
conditions:  (a)  Landlord shall have closed the Tenant Improvement Loan
referred to in Section 3.1 of that certain Lease Agreement, dated October 2,
1996, by and between the Company and Landlord (the "Lease") and shall have
disbursed proceeds from such Tenant Improvement Loan of at least $5,000,000 to
the Company; or (b) in the event the Company waives Landlord's obligation to
procure the Tenant Improvement Loan under the Lease, Landlord shall have
procured a written loan commitment on the terms and conditions described in
Section 3.1(c) of the Lease from a lender meeting the qualifications set forth
in Section 3.1(c) of the Lease.  Upon the completion of one of the two
conditions set forth in the preceding sentence prior to the Expiration Date,
this Warrant shall be exercisable upon the terms and conditions set forth
herein.  If neither of the two


                                     1
<PAGE>


conditions is satisfied prior to the Expiration Date, this Warrant shall not
become exercisable and shall expire and be of no further force or effect.

    1.2. GENERAL.  Subject to the requirements of Section 1.1 above, this
Warrant is exercisable at the option of the holder of record hereof up to the
Expiration Date for all or any part of the shares of Common Stock (but not for a
fraction of a share) which may be purchased hereunder.  The Company agrees that
the shares of Common Stock purchased under this Warrant shall be and are deemed
to be issued to the Holder hereof as the record owner of such shares as of the
close of business on the date on which this Warrant shall have been surrendered,
properly endorsed, the completed, executed Form of Subscription delivered and
payment made for such shares.  Certificates for the shares of Common Stock so
purchased, together with any other securities or property to which the Holder
hereof is entitled upon such exercise, shall be delivered to the Holder hereof
by the Company at the Company's expense within a reasonable time after the
rights represented by this Warrant have been so exercised.  In case of a
purchase of less than all the shares which may be purchased under this Warrant,
the Company shall cancel this Warrant and execute and deliver a new Warrant or
Warrants of like tenor for the balance of the shares purchasable under the
Warrant surrendered upon such purchase to the Holder hereof within a reasonable
time.  Each stock certificate so delivered shall be in such denominations of
Common Stock as may be requested by the Holder hereof and shall be registered in
the name of such Holder. 

    1.3. NET ISSUE EXERCISE.  Notwithstanding any provisions herein to the 
contrary, if the fair market value of one share of the Company's Common Stock 
is greater than the Stock Purchase Price (at the date of calculation as set 
forth below), in lieu of exercising this Warrant for cash, the Holder may 
elect to receive shares equal to the value (as determined below) of this 
Warrant (or the portion thereof being canceled) by surrender of this Warrant 
at the principal office of the Company together with the properly endorsed 
Form of Subscription and notice of such election in which event the Company 
shall issue to the Holder a number of shares of Common Stock computed using 
the following formula:

              X = Y (A-B)
                  -------
                    A

         Where      X =  the number of shares of Common Stock to be issued to 
                         the Holder
 
                    Y =  the number of shares of Common Stock purchasable 
                         under the Warrant or, if only a portion of the 
                         Warrant is being exercised, the portion of the Warrant 
                         being canceled (at the date of such calculation)

                    A =  the fair market value of one share of the Company's 
                         Common Stock (at the date of such calculation)

                                      2
<PAGE>

                    B =  Stock Purchase Price (as adjusted to the date of such 
                         calculation)

For purposes of the above calculation, if the Common Stock is traded in a 
public market, the fair market value of one share of Common Stock shall be the 
average of the closing price of the Company's Common Stock reported for each 
of the five (5) business days immediately preceding the business day on which 
Holder delivers the Form of Subscription to the Company.  If the Common Stock 
is not traded in a public market, fair market value of one share of Common 
Stock shall be determined by the Company's Board of Directors in good faith.  
The Company and the Holder agree to report any exercise under this Section 1.3 
for federal and state income tax purposes in the following manner:  Holder 
will be treated as having excised a portion of the Warrant for X shares of the 
Company's Common Stock, and having paid the Stock Purchase Price due upon such 
exercise by surrendering to the Company another portion of the Warrant 
exercisable for a number of shares equal to Y-X, with such surrender portion 
of the Warrant valued at (Y-X)(A-B).

2.  SHARES TO BE FULLY PAID; RESERVATION OF SHARES.  The Company covenants and 
agrees that all shares of Common Stock which may be issued upon the exercise of
the rights represented by this Warrant will, upon issuance, be duly authorized,
validly issued, fully paid and nonassessable and free from all preemptive 
rights of any shareholder and free of all taxes, liens and charges with 
respect to the issue thereof. The Company further covenants and agrees that, 
during the period within which the rights represented by this Warrant may be 
exercised, the Company will at all times have authorized and reserved, for the 
purpose of issue or transfer upon exercise of the subscription rights evidenced 
by this Warrant, a sufficient number of shares of authorized but unissued Common
Stock, or other securities and property, when and as required to provide for 
the exercise of the rights represented by this Warrant.  The Company will take 
all such action as may be necessary to assure that such shares of Common Stock 
may be issued as provided herein without violation of any applicable law or 
regulation, or of any requirements of any domestic securities exchange upon 
which the Common Stock may be listed; provided, however, that the Company 
shall not be required to effect a registration under Federal or State 
securities laws with respect to such exercise.  The Company will not take any 
action which would result in any adjustment of the Stock Purchase Price (as 
set forth in Section 3 hereof) if the total number of shares of Common Stock 
issuable after such action upon exercise of all outstanding warrants, together 
with all shares of Common Stock then outstanding and all shares of Common 
Stock then issuable upon exercise of all options and upon the conversion of 
all convertible securities then outstanding, would exceed the total number of 
shares of Common Stock then authorized by the Company's Restated Articles of 
Incorporation.

3.  ADJUSTMENT OF STOCK PURCHASE PRICE AND NUMBER OF SHARES.  The Stock 
Purchase Price and the number of shares purchasable upon the exercise of this 
Warrant shall be subject to adjustment from time to time upon the occurrence 
of certain events described in this Section 3.  Upon each adjustment of the 
Stock Purchase Price, the Holder of this Warrant shall thereafter be entitled 
to purchase, at the Stock Purchase Price resulting from such adjustment, the 
number of shares obtained by multiplying the Stock Purchase Price in effect 
immediately prior to such adjustment by the number of shares purchasable 
pursuant hereto immediately prior to such 
                                     3
<PAGE>

adjustment, and dividing the product thereof by the Stock Purchase Price 
resulting from such adjustment.

    3.1. SUBDIVISION OR COMBINATION OF STOCK.  In case the Company shall at 
any time subdivide its outstanding shares of Common Stock into a greater 
number of shares, the Stock Purchase Price in effect immediately prior to 
such subdivision shall be proportionately reduced, and conversely, in case 
the outstanding shares of Common Stock of the Company shall be combined into 
a smaller number of shares, the Stock Purchase Price in effect immediately 
prior to such combination shall be proportionately increased.

    3.2. DIVIDENDS IN COMMON STOCK, OTHER STOCK, PROPERTY, RECLASSIFICATION.  
If at any time or from time to time the Holders of Common Stock (or any 
shares of stock or other securities at the time receivable upon the exercise 
of this Warrant) shall have received or become entitled to receive, without 
payment therefor,

         (a)  Common Stock or any shares of stock or other securities which 
are at any time directly or indirectly convertible into or exchangeable for 
Common Stock, or any rights or options to subscribe for, purchase or 
otherwise acquire any of the foregoing by way of dividend or other 
distribution,

         (b)  any cash paid or payable otherwise than as a cash dividend, or

         (c)  Common Stock or additional stock or other securities or 
property (including cash) by way of spinoff, split-up, reclassification, 
combination of shares or similar corporate rearrangement, (other than shares 
of Common Stock issued as a stock split or adjustments in respect of which 
shall be covered by the terms of Section 3.1 above), then and in each such 
case, the Holder hereof shall, upon the exercise of this Warrant, be entitled 
to receive, in addition to the number of shares of Common Stock receivable 
thereupon, and without payment of any additional consideration therefor, the 
amount of stock and other securities and property (including cash in the 
cases referred to in clause (b) above and this clause (c)) which such Holder 
would hold on the date of such exercise had he been the holder of record of 
such Common Stock as of the date on which holders of Common Stock received or 
became entitled to receive such shares or all other additional stock and 
other securities and property.

    3.3. REORGANIZATION, RECLASSIFICATION, CONSOLIDATION, MERGER OR SALE.  If 
any recapitalization, reclassification or reorganization of the capital stock 
of the Company, or any consolidation or merger of the Company with another 
corporation, or the sale of all or substantially all of its assets or other 
transaction shall be effected in such a way that holders of Common Stock 
shall be entitled to receive stock, securities, or other assets or property 
(an "Organic Change"), then, as a condition of such Organic Change, lawful 
and adequate provisions shall be made by the Company whereby the Holder 
hereof shall thereafter have the right to purchase and receive (in lieu of 
the shares of the Common Stock of the Company immediately theretofore 
purchasable and receivable upon the exercise of the rights represented 
hereby) such shares of stock, securities or other assets or property as may 
be issued or payable with respect to or in exchange for a number of 
outstanding shares of such Common Stock equal to the number of 
                                     4
<PAGE>

shares of such stock immediately theretofore purchasable and receivable upon 
the exercise of the rights represented hereby; provided, however, that in the 
event the value of the stock or securities (determined in good faith by the 
Board of Directors of the Company) issuable or payable with respect to one 
share of the Common Stock of the Company immediately theretofore purchasable 
and receivable upon the exercise of the rights represented hereby is in 
excess of the Stock Purchase Price hereof effective at the time of a merger 
and the stock or securities received in such reorganization, if any, are 
publicly traded and are freely tradeable by the Holder under Rule 144 or 145 
under the Securities Act of 1933, as amended, then this Warrant shall expire 
unless exercised prior to such Organic Change.  In the event of any Organic 
Change, appropriate provision shall be made by the Company with respect to 
the rights and interests of the Holder of this Warrant to the end that the 
provisions hereof (including, without limitation, provisions for adjustments 
of the Stock Purchase Price and of the number of shares purchasable and 
receivable upon the exercise of this Warrant) shall thereafter be applicable, 
in relation to any shares of stock, securities or assets thereafter 
deliverable upon the exercise hereof.

    3.4.      CERTAIN EVENTS.  If any change in the outstanding Common Stock 
of the Company or any other event occurs as to which the other provisions of 
this Section 3 are not strictly applicable or if strictly applicable would 
not fairly protect the purchase rights of the Holder of the Warrant in 
accordance with such provisions, then the Board of Directors of the Company 
shall make an adjustment in the number and class of shares available under 
the Warrant, the Stock Purchase Price or the application of such provisions, 
so as to protect such purchase rights as aforesaid.  The adjustment shall be 
such as will give the Holder of the Warrant upon exercise for the same 
aggregate Stock Purchase Price the total number, class and kind of shares as 
he would have owned had the Warrant been exercised prior to the event and had 
he continued to hold such shares until after the event requiring adjustment.

    3.5. NOTICES OF CHANGE.

         (a)  Promptly following any adjustment in the number or class of 
shares subject to this Warrant and of the Stock Purchase Price, the Company 
shall give written notice thereof to the Holder, setting forth in reasonable 
detail and certifying the calculation of such adjustment.

         (b)  The Company shall give written notice to the Holder at least 10 
business days prior to the date on which the Company closes its books or 
takes a record for determining rights to receive any dividends or 
distributions.

         (c)  The Company shall also give written notice to the Holder at 
least 15 business days prior to the date on which an Organic Change shall 
take place.

4.  ISSUE TAX.  The issuance of certificates for shares of Common Stock upon 
the exercise of the Warrant shall be made without charge to the Holder of the 
Warrant for any issue tax (other than any applicable income taxes) in respect 
thereof; provided, however, that the Company shall not be required to pay any 
tax which may be payable in respect of any transfer involved in the 

                                     5
<PAGE>

issuance and delivery of any certificate in a name other than that of the 
then Holder of the Warrant being exercised.

5.  CLOSING OF BOOKS.  The Company will at no time close its transfer books 
against the transfer of any warrant or of any shares of Common Stock issued 
or issuable upon the exercise of any warrant in any manner which interferes 
with the timely exercise of this Warrant.

6.  NO VOTING OR DIVIDEND RIGHTS; LIMITATION OF LIABILITY.  Nothing contained 
in this Warrant shall be construed as conferring upon the Holder hereof the 
right to vote or to consent or to receive notice as a shareholder of the 
Company or any other matters or any rights whatsoever as a shareholder of the 
Company.  No dividends or interest shall be payable or accrued in respect of 
this Warrant or the interest represented hereby or the shares purchasable 
hereunder until, and only to the extent that, this Warrant shall have been 
exercised.  No provisions hereof, in the absence of affirmative action by the 
holder to purchase shares of Common Stock, and no mere enumeration herein of 
the rights or privileges of the holder hereof, shall give rise to any 
liability of such Holder for the Stock Purchase Price or as a shareholder of 
the Company, whether such liability is asserted by the Company or by its 
creditors.

7.  WARRANTS TRANSFERABLE.  Subject to compliance with applicable federal and 
state securities laws, this Warrant and all rights hereunder are 
transferable, in whole or in part, without charge to the holder hereof 
(except for transfer taxes), upon surrender of this Warrant properly 
endorsed.  Each taker and holder of this Warrant, by taking or holding the 
same, consents and agrees that this Warrant, when endorsed in blank, shall be 
deemed negotiable, and that the holder hereof, when this Warrant shall have 
been so endorsed, may be treated by the Company, at the Company's option, and 
all other persons dealing with this Warrant as the absolute owner hereof for 
any purpose and as the person entitled to exercise the rights represented by 
this Warrant, or to the transfer hereof on the books of the Company any 
notice to the contrary notwithstanding; but until such transfer on such 
books, the Company may treat the registered owner hereof as the owner for all 
purposes.

8.  RIGHTS AND OBLIGATIONS SURVIVE EXERCISE OF WARRANT.  The rights and 
obligations of the Company, of the holder of this Warrant and of the holder 
of shares of Common Stock issued upon exercise of this Warrant, referred to 
in Section 7 shall survive the exercise of this Warrant.

9.  MODIFICATION AND WAIVER.  This Warrant and any provision hereof may be 
changed, waived, discharged or terminated only by an instrument in writing 
signed by the party against which enforcement of the same is sought.

10. NOTICES.  Any notice, request or other document required or permitted to 
be given or delivered to the holder hereof or the Company shall be delivered 
or shall be sent by certified mail, postage prepaid, to each such holder at 
its address as shown on the books of the Company or to the Company at the 
address indicated therefor in the first paragraph of this Warrant or such 
other address as either may from time to time provide to the other.

                                     6
<PAGE>

11. BINDING EFFECT ON SUCCESSORS.  This Warrant shall be binding upon any 
corporation succeeding the Company by merger, consolidation or acquisition of 
all or substantially all of the Company's assets.  All of the obligations of 
the Company relating to the Common Stock issuable upon the exercise of this 
Warrant shall survive the exercise and termination of this Warrant.  All of 
the covenants and agreements of the Company shall inure to the benefit of the 
successors and assigns of the holder hereof.  

12. DESCRIPTIVE HEADINGS AND GOVERNING LAW.  The description headings of the 
several sections and paragraphs of this Warrant are inserted for convenience 
only and do not constitute a part of this Warrant.  This Warrant shall be 
construed and enforced in accordance with, and the rights of the parties 
shall be governed by, the laws of the State of California.

13. LOST WARRANTS.  The Company represents and warrants to the Holder hereof 
that upon receipt of evidence reasonably satisfactory to the Company of the 
loss, theft, destruction, or mutilation of this Warrant and, in the case of 
any such loss, theft or destruction, upon receipt of an indemnity reasonably 
satisfactory to the Company, or in the case of any such mutilation upon 
surrender and cancellation of such Warrant, the Company, at its expense, will 
make and deliver a new Warrant, of like tenor, in lieu of the lost, stolen, 
destroyed or mutilated Warrant.  

14. FRACTIONAL SHARES.  No fractional shares shall be issued upon exercise of 
this Warrant.  The Company shall, in lieu of issuing any fractional share, 
pay the holder entitled to such fraction a sum in cash equal to such fraction 
multiplied by the then effective Stock Purchase Price.

                        [THIS SPACE INTENTIONALLY LEFT BLANK]
                                     7
<PAGE>

    IN WITNESS WHEREOF, the Company has caused this Warrant to be duly 
executed by its officers, thereunto duly authorized this 1st day of November, 
1996.

                                  INHALE THERAPEUTIC SYSTEMS,
                                  a California corporation


                                      /s/ Robert B. Chess
                                  ----------------------------
                                       Robert B. Chess
                                       President

ATTEST:


/s/ Mark P. Tanoury
- ---------------------------
Mark P. Tanoury
Secretary


                                     8
<PAGE>


                                      EXHIBIT A
                                           
                                  SUBSCRIPTION FORM
                                           
                                               Date:                 , 19
                                                    ------------------    ----

Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

/ /  The undersigned hereby elects to exercise the warrant issued to it by 
     Inhale Therapeutic Systems (the "Company") and dated November 1, 1996
     Warrant No. CSW-2 (the "Warrant") and to purchase thereunder 
     __________________________________ shares of the Common Stock of the 
     Company (the "Shares") at a purchase price of _______________________ 
     Dollars ($__________) per Share or an aggregate purchase price of 
     ____________________ Dollars ($__________) (the      "Purchase Price").

/ /  The undersigned hereby elects to convert _______________________ percent 
     (____%) of the value of the Warrant pursuant to the provisions of Section 
     1.3 of the Warrant.

     Pursuant to the terms of the Warrant the undersigned has delivered the 
Purchase Price herewith in full in cash or by certified check or wire 
transfer.  The undersigned also makes the representations set forth on the 
attached Exhibit B of the Warrant.

                              Very truly yours,

                              --------------------------------


                              By:
                                 -----------------------------

                              Title:
                                    --------------------------


<PAGE>

                                      EXHIBIT B
                                           
                              INVESTMENT REPRESENTATION
                                           
                                                Date:                 , 19
                                                    ------------------    ----


Inhale Therapeutic Systems
1060 East Meadow Circle
Palo Alto, CA 94303

Attn:  President

Ladies and Gentlemen:

     The undersigned, _________________________ ("Purchaser"), intends to 
acquire up to ______________ shares of the Common Stock (the "Common Stock") 
of Inhale Therapeutic Systems (the "Company") from the Company pursuant to 
the exercise of that certain Warrant to purchase Common Stock held by 
Purchaser.  The Common Stock will be issued to Purchaser in a transaction not 
involving a public offering and pursuant to an exemption from registration 
under the Securities Act of 1933, as amended (the "1933 Act") and applicable 
state securities laws.  In connection with such purchase and in order to 
comply with the exemptions from registration relied upon by the Company, 
Purchaser represents, warrants and agrees as follows:

     Purchaser is acquiring the Common Stock for its own account, to hold for 
investment, and Purchaser shall not make any sale, transfer or other 
disposition of the Common Stock in violation of the 1933 Act or the General 
Rules and Regulations promulgated thereunder by the Securities and Exchange 
Commission (the "SEC") or in violation of any applicable state securities law.

     Purchaser has been advised that the Common Stock has not been registered 
under the 1933 Act or state securities laws on the ground that this 
transaction is exempt from registration, and that reliance by the Company on 
such exemptions is predicated in part on Purchaser's representations set 
forth in this letter.

     Purchaser has been informed that under the 1933 Act, the Common Stock 
must be held indefinitely unless it is subsequently registered under the 1933 
Act or unless an exemption from such registration (such as Rule 144) is 
available with respect to any proposed transfer or disposition by Purchaser 
of the Common Stock.  Purchaser further agrees that the Company may refuse to 
permit Purchaser to sell, transfer or dispose of the Common Stock (except as 
permitted under Rule 144) unless there is in effect a registration statement 
under the 1933 Act and any applicable state securities laws covering such 
transfer, or unless Purchaser furnishes an opinion of counsel reasonably 
satisfactory to counsel for the Company, to the effect that such registration 
is not required.

<PAGE>

     Purchaser also understands and agrees that there will be placed on the 
certificate(s) for the Common Stock, or any substitutions therefor, a legend 
stating in substance:
     
          "The shares represented by this certificate have not been 
     registered under the Securities Act of 1933, as amended (the      
     "Securities Act"), or any state securities laws.  These shares
     have been acquired for investment and may not be sold or otherwise      
     transferred in the absence of an effective registration statement
     for these shares under the Securities Act and applicable state
     securities laws, or an opinion of counsel satisfactory to the
     Company that registration is not required and that an applicable
     exemption is available."
     
     Purchaser has carefully read this letter and has discussed its 
requirements and other applicable limitations upon Purchaser's resale of 
the Common Stock with Purchaser's counsel.

                              Very truly yours,

                              --------------------------------


                              By:
                                 -----------------------------

                              Title:
                                    --------------------------

                                     3



<PAGE>

                                           
                                           
                                           
                                           
                                           
                             SUBLEASE AND LEASE AGREEMENT
                                           


                                       Landlord
                                 TMT Associates, LLC


                                        Tenant
                              Inhale Therapeutic Systems



                               DATED:  October 2, 1996




                                 1515 Industrial Way
                                 Belmont, California


<PAGE>
                                    LEASE SUMMARY

Parties:

          Landlord: TMT Associates, LLC.

          Tenant:   Inhale Therapeutic Systems.

Premises:           A portion of the building located at 1515 Industrial Way,
                    Belmont, California. 

Floor Area:         Initially approximately 121,390 square feet, to be increased
                    and confirmed in accordance with the provisions of
                    Paragraph 1.

Commencement
Date:               The date of this Sublease and Lease Agreement.

Expiration Date:    Fifteen (15) years following the last day of the calendar
                    month which includes the Rent Commencement Date (as
                    defined in Paragraph 2.2 below).

Scheduled Rent
Commencement
Date:               To be determined in accordance with the provisions of
                    Paragraph 2.

Rent:               Initial Base Rent of approximately $40, 300.00 per month, to
                    be confirmed in accordance with the provisions of 
                    Paragraph 1 and increased in accordance with the
                    provisions of Paragraph 3.


Security Deposit:   $80,600.00

Tenant's Share of Building:   Initially 54%, to be increased and confirmed
pursuant to the provisions of Paragraph 1.

Options to Extend:  Three (3) options to extend the term for periods of five (5)
years each.

<PAGE>



                                  TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                                                 PAGE
                                                                                 ----
<S>                                                                              <C>
1. Initial Sublease; Premises; Option to Expand; Right of First Refusal. . . . . . .1

2. Term and Delivery of Possession . . . . . . . . . . . . . . . . . . . . . . . . .5
     2.1 Term. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
     2.2 Rent Commencement Date. . . . . . . . . . . . . . . . . . . . . . . . . . .5

3. Rent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
     3.1 Initial Base Rent . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
     3.2 Rental Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
     3.3 Manner of Payment . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
     3.4 Late Payment Charge . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

4. Security Deposit. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

5. Taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
     5.1 Tenant's Personal Property. . . . . . . . . . . . . . . . . . . . . . . . 11
     5.2 Real Property Taxes . . . . . . . . . . . . . . . . . . . . . . . . . . . 11

6. Use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
     6.1 Permitted Uses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
     6.2 Compliance with Law . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
     6.3 Hazardous Materials . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
     6.4 Restrictions on Use . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

7. Direct Operating Expenses . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
     7.1 Landlord to Maintain and Control Outside Areas. . . . . . . . . . . . . . 16
     7.2 Tenant to Pay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
     7.3 Monthly Payments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18

8. Maintenance and Repairs . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
     8.1 Tenant's Obligations. . . . . . . . . . . . . . . . . . . . . . . . . . . 18
     8.2 Landlord's Obligations. . . . . . . . . . . . . . . . . . . . . . . . . . 19

9. Alterations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
     9.1 Landlord's Consent Required . . . . . . . . . . . . . . . . . . . . . . . 19
     9.2 Plans and Permits . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
     9.3 Construction Work Done by Tenant. . . . . . . . . . . . . . . . . . . . . 20
     9.4 Roof Repairs. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
     9.5 Title to Alterations. . . . . . . . . . . . . . . . . . . . . . . . . . . 20
     9.6 Removal of Alterations. . . . . . . . . . . . . . . . . . . . . . . . . . 20

10. Mechanics' Liens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

11. Utilities. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

12. Indemnity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

13. Waiver of Claims . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

                                           i

<PAGE>

14. Insurance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
     14.1 Tenant's Liability Insurance . . . . . . . . . . . . . . . . . . . . . . 22
     14.2 Landlord's Liability Insurance . . . . . . . . . . . . . . . . . . . . . 22
     14.3 Property Insurance . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
     14.4 Payment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
     14.5 Insurance Policies . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
     14.6 Waiver of Subrogation. . . . . . . . . . . . . . . . . . . . . . . . . . 24
     14.7 No Limitation of Liability . . . . . . . . . . . . . . . . . . . . . . . 24
     14.8 Impounding of Premiums . . . . . . . . . . . . . . . . . . . . . . . . . 24

15. Damage or Destruction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
     15.1 Partial Damage-Insured . . . . . . . . . . . . . . . . . . . . . . . . . 25
     15.2 Partial Damage-Uninsured . . . . . . . . . . . . . . . . . . . . . . . . 25
     15.3 Total Destruction. . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
     15.4 Damage Near End of Term. . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.5 Abatement of Rent. . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.6 Waiver . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.7 Tenant's Property. . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.8 Notice of Damage . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.9 Replacement Cost . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
     15.10 Tenant's Cancellation Right . . . . . . . . . . . . . . . . . . . . . . 27

16. Condemnation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
     16.1 Partial Taking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
     16.2 Total Taking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
     16.3 Distribution of Award. . . . . . . . . . . . . . . . . . . . . . . . . . 27
     16.4 Sale Under Threat of Condemnation. . . . . . . . . . . . . . . . . . . . 27
     16.5 Temporary Taking . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28

17. Assignment and Subletting. . . . . . . . . . . . . . . . . . . . . . . . . . . 28
     17.1 Documentation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
     17.2 Terms and Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . 28
     17.3 Partnership. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
     17.4 Permitted Transfers. . . . . . . . . . . . . . . . . . . . . . . . . . . 29
     17.5 Landlord's Remedies. . . . . . . . . . . . . . . . . . . . . . . . . . . 29
     17.6 Encumbrances, Licenses and Concession Agreements . . . . . . . . . . . . 29

18. Default by Tenant. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
     18.1 Event of Default . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
     18.2 Remedies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
     18.3 No Relief From Forfeiture After Default. . . . . . . . . . . . . . . . . 32
     18.4 Landlord's Right to Perform Tenant's Obligations . . . . . . . . . . . . 32
     18.5 Interest on Past Due Obligations . . . . . . . . . . . . . . . . . . . . 32
     18.6 Additional Rent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
     18.7 Remedies Not Exclusive . . . . . . . . . . . . . . . . . . . . . . . . . 32

19. Default by Landlord. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
     19.1 Cure Period. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
     19.2 Mortgagee Protection . . . . . . . . . . . . . . . . . . . . . . . . . . 33

20. Advertisements and Signs . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

21. Entry by Landlord. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

22. Subordination, Attornment and Non-Disturbance. . . . . . . . . . . . . . . . . 33

                                           ii

<PAGE>

     22.1 Subordination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
     22.2 Attornment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
     22.3 Non-Disturbance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

23. Estoppel Certificates and Financial Statements . . . . . . . . . . . . . . . . 34

24. Notices. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

25. Waiver . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

26. No Accord and Satisfaction . . . . . . . . . . . . . . . . . . . . . . . . . . 35

27. Attorney's Fees. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35

28. Surrender. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35

29. Holding Over . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35

30. Transfer of Premises by Landlord . . . . . . . . . . . . . . . . . . . . . . . 36

31. Rules and Regulations of Building. . . . . . . . . . . . . . . . . . . . . . . 36

32. General Provisions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.1 Entire Agreement . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.2 Time . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.3 Captions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.4 California Law . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.5 Gender; Singular and Plural. . . . . . . . . . . . . . . . . . . . . . . 37
     32.6 Partial Invalidity . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.7 No Warranties. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.8 Joint and Several Liability. . . . . . . . . . . . . . . . . . . . . . . 37
     32.9 Successors and Assigns . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.10 Rules and Regulations . . . . . . . . . . . . . . . . . . . . . . . . . 37
     32.11 Authority . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     32.12 Memorandum of Lease . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     32.13 Merger. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     32.14 Force Majeure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     32.15 Real Estate Brokers . . . . . . . . . . . . . . . . . . . . . . . . . . 38

33. Option(s) to Extend. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     33.1 Options. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
     33.2  Extended Term Rent. . . . . . . . . . . . . . . . . . . . . . . . . . . 39

34. Performance of Landlord's Work; Construction of Tenant Improvements. . . . . . 40
     34.1  Definitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
     34.2  Procedures and Time Schedules . . . . . . . . . . . . . . . . . . . . . 41
     34.3  Delivery of Possession. . . . . . . . . . . . . . . . . . . . . . . . . 43


EXHIBITS

Exhibit "A" - Premises/Tenant Improvements/Parking Areas
Exhibit "B" - Option Agreement
Exhibit "C" - List of Hazardous Material Reports
</TABLE>

                                           iii

<PAGE>

                             SUBLEASE AND LEASE AGREEMENT


     This Sublease and Lease Agreement (this "Lease") is made and entered into
as of October 2, 1996. by and between TMT Associates, LLC, a California limited
liability company, a California corporation ("Landlord"), whose address is 1515
Industrial Way, Belmont, California 94002 and Inhale Therapeutic Systems, a
California corporation ("Tenant"), whose present address is 1060 E. Meadow
Circle, Palo Alto, California  94303 but from and after the Rent Commencement
Date (as defined below) shall be the address of the premises, which is 1515
Industrial Way, Belmont, California 94002.

     Landlord and Tenant agree to the terms, covenants and conditions of this
Lease, as follows:

     1.   INITIAL SUBLEASE; PREMISES; OPTION TO EXPAND; RIGHT OF FIRST REFUSAL. 
As of the date of this Lease, Landlord is the lessee of the Project (as defined
below) as assignee of the tenant's interest under that certain Standard
Industrial/Commercial Single-Tenant Lease-Net (the "Master Lease") dated
November 15, 1995, by and between Landlord's predecessor in interest, KLN
Precision Machining Corporation ("KLN"), and Intrinsic Ventures, Inc., W.L.
Butler Investment Corporation, and Sharp Development Company (collectively,
"Master Landlord").  All of the interest of the Master Landlord under the Master
Lease has been assigned to Intrinsic Ventures, Inc.  Landlord also holds the
right to purchase the Project pursuant to the terms of, and as the assignee of
the optionee's interest under, that certain Option Agreement (the "Master Option
Agreement") dated November 15, 1995, by and between KLN, as optionee, and Master
Landlord, as optionor.  Landlord is not permitted under the Master Option
Agreement to acquire title to the Project until on or after October 27, 1997. 
Until Landlord's acquisition of the Project pursuant to the Option Agreement,
this Lease shall be a sublease by and between Landlord, as sublessor, and
Tenant, as sublessee, which sublease shall be subject and subordinate to the
Master Lease.  The consent of the Master Landlord to this Lease is not required
under the Master Lease.  The terms and conditions of the Master Lease shall not
be incorporated into this Lease, with the effect that the rights and obligations
of Landlord and Tenant with respect to the premises shall be exclusively set
forth in this Lease and the Option Agreement by and between Landlord and Tenant,
as described in Paragraph 2.1 below.  The following shall be conditions to
Tenant's obligations under this Lease:  (a) on or before November 4, 1996, the
Master Landlord shall execute and deliver a non-disturbance agreement for the
benefit of Tenant in a form reasonably acceptable to Tenant, (b) on or before
October 26, 1996, Tenant's Board of Directors shall approve this Lease, (c) on
or before October 15, 1996, Tenant shall have approved that certain report
entitled Phase II Site Investigation Results prepared by Geomatrix Consultants,
Inc., dated November, 1994, and (d) on or before March 1, 1997, Landlord shall
complete Landlord's Work (as defined in Paragraph 34.1(a) below).  In the event
of a failure of any of the above conditions, Tenant shall have the right to
cancel this Lease by delivery of written notice to Landlord of such cancellation
on or before the date which is five (5) business days after the applicable date
for satisfaction of each condition set forth above, after which date Tenant
shall have no further right to cancel this Lease due to the failure of the
applicable condition.  Notwithstanding the condition for Tenant's benefit set
forth in subparagraph (d) above, Tenant shall not be entitled to cancel this
Lease due to a failure of such condition if prior to March 1, 1997, Tenant
exercises it right to complete Landlord's Work set forth in Paragraph 34.2(f)
below.  In the event of any such cancellation the Deposit (as defined in
Paragraph 4 below) shall be returned to Tenant and neither party shall have any
further obligations under this Lease.  Upon Landlord's acquisition of the
Project pursuant to the terms of the Master Option Agreement, this Lease shall
be a direct lease between Landlord and Tenant on all the terms and conditions
set forth herein.  Landlord


                                       1

<PAGE>


will use due diligence and all commercially reasonable efforts to enforce 
Landlord's rights under the Master Lease to protect and give effect to all 
rights of Tenant under this Lease.  

          Landlord hereby leases to Tenant and Tenant hereby leases from
Landlord for the term, at the rental, and upon all of the other terms, covenants
and conditions set forth herein, the premises described below, which is part of
a building located on a parcel of land situated in the County of San Mateo,
State of California, as shown on Exhibit "A" attached hereto and more
particularly described as follows:

     Parcel 2, as said parcel is delineated upon that certain Parcel Map
entitled "Being all of the Lands of W.L. Butler Investment Corporation et al, as
described in Instrument No. 95140475, O.R. San Mateo County Records, San Mateo
County California," which Parcel Map was filed in the Office of the Recorder,
County of San Mateo, State of California on June 13, 1996, in Book 69 of Maps,
at Pages 26 and 27.

     The premises shall initially consist of approximately 121,390 square feet
of the building, designated as Phase I on Exhibit A.  Tenant shall have the
option to expand the premises as provided in this Paragraph 1. Tenant may expand
the premises to include the additional 23,201 square feet designated as Phase II
on Exhibit A, by delivery of written notice of exercise of its option to expand
the premises by the date which is six (6) months prior to the date Tenant
desires to occupy the Phase II space for the purpose of installation and
construction of Tenant's desired improvements to such space, which shall be at
Tenant's sole cost.  In the event of such exercise, the Phase II space shall be
delivered to Tenant by Landlord as soon as possible, but not later than the date
which is six (6) months following Landlord's receipt of Tenant's exercise of its
expansion option.  Landlord shall deliver the expansion space in a broom clean
condition, with all Hazardous Materials (as defined in Paragraph 6.3(a) below)
and all of Landlord's personal property and equipment removed,  provided that
Landlord shall not have any obligation to demolish or remove any partitions,
building operating systems or similar improvements installed in such space (such
condition hereinafter referred to as the "Vacant Condition").  The Phase II
space shall be added to the premises for all purposes of this Lease, including,
but not limited to, the payment of Base Rent pursuant to Paragraph 3.1 below,
effective as of the date which is the earlier of:  (i) six (6) months after
Landlord's delivery of the Phase II space in Vacant Condition, or (ii) the date
Tenant first commences use of the Phase II space.  Tenant's early entry into the
Phase II space for the purpose of constructing improvements shall be subject to
the following conditions:  (a) Tenant shall cause the insurance policies which
Tenant is required to maintain under Paragraph 14 below to be applicable to
Tenant's activities in the expansion space prior to its inclusion in the
premises, and (b) the provisions of Paragraphs 9, 10, 11, 12 and 13 below shall
be applicable to Tenant's entry into and activities in the expansion space prior
to its inclusion in the premises.  The terms and conditions applicable to
Tenant's entry into the expansion space set forth in the immediately preceding
sentence shall be referred to herein as the "Early Entry Conditions".  Unless
Tenant has previously exercised such option with the effect that the Phase II
space is already included within the premises, the Phase II space shall be added
to the premises for all purposes of this Lease effective as of the first (1st)
day of the fourth (4th) year of the term of the Lease.  Upon or following the
inclusion of the Phase II space in the premises, Tenant shall have an additional
option to expand the premises to include the 24,066 square feet designated as
Phase III on Exhibit A, by delivery of written notice of such exercise by the
date which is twenty-four (24) months prior to the date Tenant desires to occupy
the Phase III space for the purpose of installation and construction of Tenant's
desired improvements to such space, which shall be at Tenant's sole cost and
shall be on the Early Entry Conditions.  In the event of such exercise, the
Phase III space shall be delivered by Landlord to Tenant in Vacant Condition not
later than the date which is twenty-four (24) months following Landlord's
receipt of Tenant's exercise of its expansion option.  If requested by Tenant,
Landlord shall use


                                       2

<PAGE>

reasonable efforts to vacate the Phase III space prior to such date in order 
to accelerate the date on which the Phase III space shall be added to the 
premises for all purposes of this Lease.  Unless Tenant has requested such 
acceleration, Tenant shall have no obligation to accept delivery of the Phase 
III space prior to the date which is eighteen (18) months after the date of 
delivery of Tenant's expansion notice for the Phase III space.  The Phase III 
space shall be added to the premises for all purposes of this Lease as of the 
date which is the earlier of:  (i) six (6) months after Landlord's delivery 
of the Phase III space to Tenant in Vacant Condition, or (ii) the date Tenant 
first commences use of the Phase III space.  If the second option to expand 
has been exercised by Tenant, then Tenant shall have the additional right to 
expand the premises to include the 56,231 square feet designated as Phase IV 
on Exhibit A, by delivery of written notice of such exercise to Landlord not 
sooner than the date which is thirty-six (36) months after the Commencement 
Date and on or before the date which is twenty-four (24) months prior to the 
date Tenant desires to occupy the Phase IV space for the purpose of 
installation and construction of Tenant's desired improvements to such space, 
which shall be at Tenant's sole cost and shall be on the Early Entry 
Conditions.  In the event of such exercise, the Phase IV space shall be 
delivered by Landlord to Tenant in Vacant Condition not later than the date 
which is twenty-four (24) months following Landlord's receipt of Tenant's 
exercise of its expansion option.  If requested by Tenant, Landlord shall use 
reasonable efforts to vacate the Phase IV space prior to such date in order 
to accelerate the date on which the Phase IV space shall be added to the 
premises for all purposes of this Lease.  Unless Tenant has requested such 
acceleration, Tenant shall have no obligation to accept delivery of the Phase 
IV space prior to the date which is eighteen (18) months after the date of 
delivery of Tenant's expansion notice for the Phase IV space.  The Phase IV 
space shall be added to the premises for all purposes of this Lease as of the 
date which is the earlier of:  (i) six (6) months after Landlord's delivery 
of the Phase IV space to Tenant in Vacant Condition, or (ii) the date Tenant 
first commences use of the Phase IV space.  Notwithstanding anything to the 
contrary set forth above, Tenant shall deliver any exercise of its options to 
expand on or before the date which is six (6) years following the 
Commencement Date, after which date Tenant shall have no further right to 
expand the premises.  The size of the premises, and the applicable dates upon 
which expansion is effected, are summarized in the chart below.

                                       3

<PAGE>

<TABLE>
<CAPTION>

APPLICABLE DATE                      SIZE OF PREMISES            TENANT'S SHARE OF BUILDING
- ---------------                ----------------------------      --------------------------
<S>                            <C>                               <C>
Upon Commencement Date              121,390 square feet,                  53.98%
                                  designated as Phase I on
                                         Exhibit A 

Six (6) months following the   144,591 square feet, additional            64.29%
earlier of delivery or use,     23,201 square feet designated
 but not later than year 4        as Phase II on Exhibit A

Six (6) months following the   168,657 square feet, additional               75%
earlier of delivery or use      24,066 square feet designated 
                                  as Phase III on Exhibit A

Six (6) months following the   224,888 square feet, additional              100%
 earlier of delivery or use     56,231 square feet designated 
                                  as Phase IV on Exhibit A 
</TABLE>

     Commencing the first (1st) day of the seventh (7th) year of the term of
this Lease, at which date Tenant shall have no further option to expand the
premises as set forth above in this Paragraph 1, Tenant shall have the right of
first refusal to lease any portion of the Building (as defined below) which is
not then leased by Tenant on the terms set forth in this Paragraph 1 below.  In
the event Landlord intends to lease any remaining space in the Building to a
third party, Landlord shall deliver to Tenant a copy of the written offer
received from such third party regarding the terms and conditions on which such
third party is willing to lease space in the Building.  Tenant shall have ten
(10) business days from receipt of the copy of the third party offer to advise
Landlord in writing whether Tenant elects to exercise its right of first refusal
with respect to that portion of the Building which is the subject of the third
party offer (the "First Right Space").  Tenant shall have the right to add the
First Right Space to the premises for all purposes of this Lease, at the Base
Rent then payable by Tenant under this Lease, for the balance of the initial
term of this Lease.  Tenant shall not have the right to match the terms and
conditions of the third party offer.  In the event Tenant elects to exercise the
right of first refusal described above, Landlord and Tenant shall execute an
appropriate amendment to this Lease which adds the First Right Space to the
premises for all purposes of this Lease with an effective date of the earlier
of:  (i) six (6) months after Tenant's election to exercise the first right of
refusal, or (ii) the date Tenant first commences use of the First Right Space. 
During the period following Tenant's exercise of its right of first refusal
until the addition of the First Right Space to the premises, Tenant shall be
permitted to enter the First Right Space for the purpose of commencing Tenant's
desired improvements thereto, which entry shall be on the Early Entry
Conditions.  In the event Tenant does not elect to exercise such right, or
Tenant fails to respond to Landlord in writing within the ten (10) business day
period set forth above, then Landlord shall be free to lease such space to such
third party for the term set forth in the offer delivered to Tenant, provided
that such lease transaction is completed within four (4) months following the
date Tenant receives a copy of such third party offer.  In the event such lease
transaction is not completed within such four (4) month period, or in the event
of an increase to the proposed term of the lease with such third party, then
Landlord shall again offer to Tenant the opportunity to lease such space in
accordance with the above provisions following the expiration of the four (4)
month period described above or delivery of written notice to Tenant of the
proposed increased term of the lease with such third party.  The right of first
refusal granted to Tenant in this Paragraph 1 shall not terminate in the event
Tenant elects, or is deemed to have elected, not to

                                      4
<PAGE>

exercise its first right of refusal and shall remain in effect throughout the 
initial term of this Lease, but shall not be in effect during any extended 
term.  

     The building described above is hereafter called the "Building."

     The portion of the Building, or the entire Building, as the case may be,
leased by Landlord to Tenant is hereafter called the "premises."

     The parcel of land described above, together with the Building and all
other improvements now or hereafter located thereon, is hereafter called the
"Project."

     The portion of the parcel of land described above not covered by the
Building is hereafter called the "Outside Areas."

     "Tenant's Share" as used in this Lease means that percentage calculated by
dividing the total number of square feet of leasable space in the Building into
the total number of leasable square feet contained in the premises, which the
parties agree initially shall be 53.98% , subject to adjustment as set forth in
the table above and by the results of the measurement described below.

     Landlord and Tenant acknowledge that the size of the Building and the
various Phases described above are estimates only, and that precise areas shall
be determined by measurement.  For the purposes of such measurement, the
Building and the various Phases shall include all areas located within the
perimeter drip line of the Building.  Such measurement shall be conducted by a
third party reasonably approved by Landlord and Tenant.  The cost of such
measurement shall be paid equally by Landlord and Tenant.  The results of such
measurement shall modify, if necessary, the Tenant's Share set forth above and
the Base Rent payable under Paragraph 3.1(a) below.

     2.     TERM AND DELIVERY OF POSSESSION.

          2.1  TERM.  The term of this Lease (the "Term") shall commence on 
the date of this Lease (the "Commencement Date"), and end on the date which 
is fifteen (15) years after the Rent Commencement Date (as defined in 
Paragraph 2.2 below), plus the number of days necessary to cause the end of 
the Term to fall on the last day of a calendar month (the "Expiration Date"), 
unless sooner terminated pursuant to the provisions hereof.  Landlord and 
Tenant have entered into that certain Option Agreement, a copy of which is 
attached hereto as Exhibit B, dated October 2, 1996, by which Landlord grants 
to Tenant the right to purchase the Project.  In the event Tenant exercises 
such option, the term of this Lease shall expire on the date of the close of 
escrow for such purchase, notwithstanding the provisions of this Paragraph 
2.1 above to the contrary.  Landlord shall deliver possession of the premises 
to Tenant on the Commencement Date.  

          2.2  RENT COMMENCEMENT DATE.  The date (the "Rent Commencement 
Date") upon which the payment of Base Rent (as defined in Paragraph 3.1 
below) shall commence shall be the earlier of: (a) the date upon which Tenant 
substantially completes (as defined in Paragraph 34.1(e) below) its desired 
improvements to the premises and receives a certificate of occupancy 
authorizing the use and occupancy of the premises, or (b) June 1, 1997.  
Notwithstanding the foregoing sentence:  (c) in the event Landlord shall not 
have completed Landlord's Work, as defined in and pursuant to Paragraph 34 
below, by December 1, 1996, the Rent Commencement Date shall be extended by 
one (1) day for each day of delay past December 1, 1996, in the completion of 
Landlord's Work, and (d) the payment of Tenant Improvement


                                      5
<PAGE>

Base Rent (as defined in Paragraph 3.1(b) below) shall commence at such time 
as installment payments are due under the Tenant Improvement Loan (as defined 
in Paragraph 3.1(b) below).  

     3.  RENT.

          3.1  INITIAL BASE RENT.

               (a)  Upon execution of this Lease, Tenant shall pay to Landlord
$40,300, which amount shall be applied to the first (1st) month for which base
rent is due in accordance with the terms of this Paragraph 3.1(a) below. 
Commencing on the Rent Commencement Date, Tenant shall pay to Landlord for each
subsequent calendar month of the term of this Lease (excepting the first (1st)
such month following the Rent Commencement Date, for which rent shall be paid by
the application of the payment described above), monthly base rent (hereafter
called "Base Rent"), in installments as follows:

                                       6
<PAGE>

Applicable Period of Lease Term (inclusive), 
             commencing upon
         Rent Commencement Date                 Monthly Base Rent
         ----------------------                 -----------------

Months 1 - 6                                       $40,300.00

Months 7 -12                                       $59,150.00

Years 2 and 3                    .65/square foot/month multiplied by the area of
                                          the premises per Paragraph 1

Year 4                                       .70/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Year 5                                       .75/square foot/month  
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Years 6 and 7                                .80/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Years 8 and 9                                .85/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Years 10 and 11                              .90/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Years 12 and 13                              .95/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Years 14 and 15                             1.00/square foot/month 
                                      multiplied by the area of the premises
                                                 per Paragraph 1

Base Rent shall be subject to adjustment from time to time as set forth in
Paragraph 3.2.  At such time as the premises is expanded pursuant to the
provisions of Paragraph 1 above, the Base Rent for the additional space added to
the premises shall be the greater of:  (i) the Base Rent rate in effect as of
the date of inclusion of such additional space in the premises, as determined in
accordance with the above schedule, or (ii) the Base Rent then in effect for the
existing premises immediately prior to such inclusion, after giving effect to
any adjustments required by Paragraph 3.2(a) below.  

               (b)  Landlord and Tenant intend that Landlord shall fund a
portion of the costs of the Tenant Improvements by payment of the Tenant's
Improvement Allowance (as such terms are defined in Paragraph 34 below) in the
amount of Five Million Dollars ($5,000,000).  Subject to the provisions of this
Paragraph 3.1(b) below, Landlord shall borrow 


                                       7
<PAGE>

the funds required to pay the Tenant's Improvement Allowance under a loan 
(the "Tenant Improvement Loan") from a third party to be secured by 
Landlord's interest in the Project.  In addition to the amount of Base Rent 
payable pursuant to the provisions of Paragraph 3.1(a) above, Base Rent shall 
also include a monthly amount (the "Tenant Improvement Base Rent") determined 
by amortizing the principal balance of the Tenant Improvement Loan over the 
period of amortization utilized to determine monthly payments under such 
loan, at the interest rate payable by Landlord under the Tenant Improvement 
Loan, plus two percent (2%) per annum.  Landlord shall use its reasonable 
best efforts and due diligence to obtain the Tenant Improvement Loan in a 
timely manner in order to permit Landlord to contribute to the costs of 
constructing the Tenant Improvements as such costs are incurred in the time 
periods contemplated by this Lease.  Tenant shall pay all reasonable costs 
and expenses incurred by Landlord to secure the Tenant Improvement Loan, 
including without limitation all lender's fees, points, legal fees, title 
insurance premiums and similar customary charges required in connection 
therewith.  Notwithstanding the immediately preceding sentence, in the event 
Landlord combines the Tenant Improvement Loan with any additional financing 
which Landlord desires to secure by the Project, then Tenant shall be 
obligated to pay only that percentage of the above described costs which is 
equal to the percentage determined by dividing the principal amount of the 
Tenant Improvement Loan by the total principal amount of the combined loan.  
At such time as Landlord has received from such third party lender written 
terms and conditions of the proposed Tenant Improvement Loan, Landlord shall 
provide Tenant with a copy of the document or correspondence which sets forth 
such terms and conditions.  Tenant shall have a period of five (5) business 
days in which to advise Landlord whether Tenant desires Landlord to proceed 
with the Tenant Improvement Loan, or whether Tenant elects not to cause 
Landlord to proceed with the Tenant Improvement Loan.  In the event that 
Landlord, despite the exercise of due diligence and reasonable best efforts 
to obtain the Tenant Improvement Loan, is unable to obtain such loan, or if 
Tenant elects not to proceed with such loan, Tenant shall fund the amount of 
the Tenant's Improvement Allowance directly, no Tenant Improvement Base Rent 
shall be payable by Tenant under this Paragraph 3.1(b), and the provisions of 
Paragraph 3.2(b) below shall apply. Landlord shall use due diligence and 
reasonable best efforts to include in the terms of the Tenant Improvement 
Loan a prepayment right on the most favorable terms possible to the borrower 
under such loan.  Subject to the provisions of Paragraph 34.2(g) below, 
Tenant shall have the right to cause Landlord to exercise such prepayment 
privilege in accordance with the terms of the Tenant Improvement Loan, on the 
condition that Tenant shall pay any prepayment premium, penalty or similar 
charge and all other costs and expenses incurred in connection with 
prepayment of the Tenant Improvement Loan.  In the event of such prepayment 
by Tenant, or upon the full repayment of the Tenant Improvement Loan, that 
portion of the Base Rent which is Tenant Improvement Base Rent shall 
terminate and shall be deleted from the monthly installment of Base Rent 
payable by Tenant under this Lease.  

               (c)  In consideration of Landlord's obligations under this Lease,
Tenant shall issue to Landlord, or directly to the members of Landlord as
Landlord shall designate, within thirty (30) days of the date of this Lease, a
warrant to purchase Tenant's common stock at the closing price for such shares
on the Commencement Date, which warrant shall be applicable to twenty thousand
(20,000) shares of Tenant's common stock. Tenant shall prepare the required
agreement regarding issuance of the warrant and take all necessary actions to
issue such warrant in compliance with federal and state securities laws.  The
agreement regarding issuance of such warrant by Tenant to Landlord or Landlord's
designee shall be in a form reasonably acceptable to Landlord and shall include
provisions that the closing of the Tenant Improvement Loan and the disbursement
of the proceeds thereof to Tenant in accordance with the terms of this Lease
shall be a condition to the exercise of such warrant.  Notwithstanding the
above, such agreement shall also provide that the warrant may be exercised by
Landlord in the event Tenant exercises its option to cause Landlord not to
procure the Tenant Improvement Loan as set forth in Paragraph 


                                       8
<PAGE>

3.1(b) above, on the condition that Landlord has made available to Tenant for 
its review a loan commitment from a third party lender not affiliated with 
Landlord, and in which Landlord has no economic interest, for a loan on the 
following terms and conditions:  (i) the interest rate payable under such 
loan shall be ten percent (10%) per annum or less, (ii) the period of 
amortization of such loan for the purposes of calculating installment 
payments thereunder shall be fifteen (15) years or longer, and (iii) the term 
of the loan shall be seven (7) years or longer.  If Landlord is able to 
produce a loan commitment on the terms and conditions described above from a 
lender meeting the qualifications described above, then Tenant shall be 
obligated to issue the warrant and Landlord shall be entitled to exercise the 
same in accordance with this Paragraph 3.1(c), notwithstanding Tenant's 
election not to close the Tenant Improvement Loan.

          3.2  RENTAL ADJUSTMENT.

               (a)  The monthly Base Rent payable hereunder may be adjusted as
of each anniversary of the Rent Commencement Date (each such date herein called
a "Rental Adjustment Date") during the term of this Lease to reflect certain
changes in the cost of living as provided below.  The adjustment or adjustments,
if any, shall be calculated upon the basis of the United States Department of
Labor, Bureau of Labor Statistics CONSUMER PRICE INDEX FOR ALL URBAN CONSUMERS,
FOR SAN FRANCISCO-OAKLAND-SAN JOSE (1982-84=100), hereafter referred to as the
"Index".  No adjustment to the Base Rent set forth in Paragraph 3.1 above shall
be made under this Paragraph 3.2 unless the Index increases by an amount greater
than eight percent (8%) in any year of the term of the Lease, each such year
commencing upon an anniversary of the Rent Commencement Date.  In the event of
any such increase in the Index, one-half (1/2) of the amount of the percentage
increase in the Index in excess of eight percent (8%) shall be added to the Base
Rent then in effect.  For example, if in any year of the term of the Lease the
Index increases ten percent (10%), then the Base Rent shall be increased by one
percent (1%) of the amount of Base Rent then in effect, such percentage increase
representing one-half (1/2) of the annual increase in the Index in excess of
eight percent (8%).  In no event shall the monthly Base Rent be reduced on any
Rental Adjustment Date.  An increase in Base Rent resulting from the application
of this Paragraph 3.2(a) shall be deemed to modify the provisions of Paragraph
3.1 above, and any scheduled increases in Base Rent set forth in Paragraph 3.1
shall be added to the modified Base Rent determined in accordance with the
provisions of this Paragraph 3.2(a).  When and if the Base Rent is determined
upon the Rental Adjustment Date, Landlord shall give Tenant written notice to
that effect indicating how the new Base Rent figure was computed in accordance
with this paragraph.  If the Index does not exist on any Rental Adjustment Date
in the same format as referred to in this paragraph, Landlord and Tenant shall
jointly select in lieu thereof an index reasonably comparable to the Index
referred to above which is then published by the Bureau of Labor Statistics, or
by a successor or similar governmental agency, or, if no governmental agency
then publishes an index, Landlord and Tenant shall jointly select any commonly
accepted index designed to reflect changes in the cost of living which is
published by a reputable private organization.

               (b)  In the event that Landlord, despite the exercise of due
diligence and reasonable best efforts to obtain the Tenant Improvement Loan, is
unable to obtain such loan on or before the date which is one (1) year from the
Rent Commencement Date, or if Tenant elects not to cause Landlord to complete
the Tenant Improvement Loan as set forth in Paragraph 3.1(b) above, then:  (i)
the Base Rent shall not include Tenant Improvement Base Rent determined in
accordance with Paragraph 3.1(b) above, and (ii) the Base Rent payable under
Paragraph 3.1(a) above shall be reduced in accordance with the provisions of
this Paragraph 3.2(b).  Commencing upon the thirteenth (13th) month following
the Rent Commencement Date, the Base Rent shall be reduced by Thirty Thousand
Twenty-Eight Dollars and Fifty-Four Cents ($30,028.54) each month for a total of
eighteen (18) consecutive months.  The parties agree such 


                                       9
<PAGE>

amount is determined by amortizing the principal amount of Five Hundred 
Thousand Dollars ($500,000) at an interest rate of ten percent (10%) per 
annum over a period of eighteen (18) months.  Landlord shall have the right, 
at any time during such eighteen (18) month period, to prepay the remaining 
principal balance of the original Five Hundred Thousand Dollar ($500,000) 
obligation without premium or penalty. Such prepayment amount shall be 
determined by calculating the then outstanding balance of principal utilizing 
the amortization criteria set forth above. Following such eighteen (18) month 
period, the Base Rent shall be fully payable in accordance with the 
provisions of this Lease.  The reduction in Base Rent described above shall 
have no effect upon the rent escalations set forth in Paragraphs 3.1(a) and 
3.2(a) above, and the deduction required by this Paragraph 3.2(b)(ii) shall 
be subtracted from the Base Rent as adjusted pursuant to such paragraphs.  

          3.3  MANNER OF PAYMENT. Tenant shall pay to Landlord the rent 
calculated as set forth above without deduction, offset, or abatement, and 
without prior notice or demand, in advance on the first day of each calendar 
month of the term of this Lease following the Rent Commencement Date.  Rent 
shall be payable in lawful money of the United States to Landlord at the 
address stated in the preamble paragraph to this Lease or to such other 
places as Landlord may from time to time designate in writing. Tenant's 
obligation to pay rent for any partial month shall be prorated on the basis 
of a thirty (30) day month.

          3.4  LATE PAYMENT CHARGE. If any installment of rent or any other 
sum due from Tenant is not received by Landlord within five (5) business days 
after the due date, Tenant shall pay to Landlord an additional sum equal to 
five percent (5) of the amount overdue as a late charge. Such late charge 
shall be added to the installment of rent due but unpaid and such sum shall 
bear interest from the date the installment of rent was due until paid at the 
rate specified in Paragraph 18.5 below.  The amount of the late charge shall 
represent liquidated damages for, and a reasonable estimate of, Landlord's 
administrative costs of collection, the exact amount of which would be 
extremely difficult or impractical to fix.  Landlord's acceptance of such 
late charge shall not excuse any default by Tenant hereunder, and shall not 
preclude Landlord from pursuing any other rights and remedies it may have 
relating to such default.

     4.   SECURITY DEPOSIT.  Upon execution of this Lease, Tenant shall 
deposit with Landlord in cash the sum of Eighty Thousand Six Hundred Dollars 
($80,600.00) (the "Deposit") as security for the faithful performance by 
Tenant of all of its obligations hereunder.  If Tenant fails to pay rent or 
any other sums due hereunder, or otherwise defaults with respect to any 
provision of this Lease, Landlord may use, apply, or retain all or any 
portion of the Deposit for the payment of any rent or other sum in default, 
or to compensate Landlord for the payment of any other sum which Landlord may 
become obligated to spend by reason of Tenant's default, or to compensate 
Landlord for any expenditures, loss or damage which Landlord may suffer 
thereby.  If Landlord so uses or applies all or any portion of the Deposit, 
Tenant shall, within ten (10) days after written demand therefor, deposit 
with Landlord an amount in cash sufficient to restore the Deposit to the full 
amount hereinabove stated.  Landlord shall not be required to keep the 
Deposit separate from its general funds.  The Deposit, less any portion 
thereof which Landlord is entitled to retain, shall be returned, without 
payment of interest, to Tenant (or to the last assignee, if any, of Tenant's 
interest hereunder) within thirty (30) days after the later of the expiration 
of the term hereof, or the date on which Tenant vacates the premises.  
Landlord and Tenant acknowledge and agree that Landlord shall be the borrower 
under the Tenant Improvement Loan, but that Tenant shall be responsible for 
the payment of all costs which arise in connection with the Tenant 
Improvement Loan and for the repayment of the Tenant Improvement Loan.  In 
the event that Tenant's cash and cash equivalents shall at any time during 
the Term or any Extended Term of this Lease be less than Ten Million Dollars 
($10,000,000), Tenant shall deposit with Landlord, as a supplement to the 
Deposit, an amount equal to the lesser 


                                       10
<PAGE>

of : (a) six (6) monthly installments actually payable by Landlord under the 
Tenant Improvement Loan at such time, or (b) the total amount of remaining 
payments under the Tenant Improvement Loan. Such supplemental amount shall be 
added to the Deposit and subject to all the terms of this Paragraph 4 above.  
On each anniversary of the Rent Commencement Date, or upon ten (10) days 
prior written notice from Landlord, an appropriate officer of Tenant shall 
certify to Landlord under the penalty of perjury that Tenant's cash and cash 
equivalents are equal to or in excess of Ten Million Dollars ($10,000,000).  
If such certification cannot be given to Landlord, then Tenant shall deliver 
to Landlord the additional payments described above.  In the event Tenant is 
required under this Paragraph 4 to make the additional deposit described 
above, and thereafter Tenant's cash and cash equivalents are equal to or in 
excess of Ten Million Dollars ($10,000,000), then upon certification of such 
fact by an appropriate officer of Tenant under the penalty of perjury, 
Landlord shall promptly return to Tenant the amount of the additional deposit 
previously made by Tenant under this Paragraph 4.  Such additional deposit 
may subsequently be required if the Tenant Improvement Loan has not been 
repaid and Tenant's cash and cash equivalents at any time during the Term or 
any Extended Term of this Lease are less than Ten Million Dollars 
($10,000,000).   

     5.   TAXES.

          5.1  TENANT'S PERSONAL PROPERTY.  Tenant shall pay directly to the 
charging authority prior to delinquency all taxes assessed against and levied 
upon Tenant's leasehold improvements, trade fixtures, furnishings, equipment 
and all other personal property and merchandise of Tenant situated in or 
about the premises.

          5.2  REAL PROPERTY TAXES.

               (a)  Tenant shall pay to Landlord Tenant's Share of all Real 
Property Taxes (as hereafter defined) levied with respect to the Project.  
Tenant shall pay to Landlord all Real Property Taxes on or before the later 
of (1) ten (10) days prior to delinquency thereof, or (2) ten (10) days after 
the date on which Tenant receives a copy of the tax bill or other reasonable 
evidence of the amount of Real Property Taxes due and payable by Tenant 
hereunder.

               (b)  The term "Real Property Taxes" as used herein shall mean 
(i) all taxes, assessments, levies, and other charges of any kind or nature 
whatsoever, general and special, foreseen and unforeseen (including all 
installments of principal and interest required to pay for any general or 
special assessments for public improvements, services, or benefits and any 
increases resulting from reassessments caused by any change in ownership, new 
construction, or change in valuation), now or hereafter imposed by any 
governmental or quasi-governmental authority or special district having the 
direct or indirect power to tax or levy assessments, which are levied or 
assessed against or with respect to (a) the value, occupancy or use of the 
Project (as now constructed or as may at any time hereinafter be constructed, 
altered, or otherwise changed), (b)the fixtures, equipment, and other real or 
personal property of Landlord that are an integral part of the Project, (c) 
the gross receipts, income, and rentals from the Project, or (d) the use of 
the Outside Areas, public utilities, or energy within the Project; (ii) all 
charges, levies or fees imposed by reason of environmental regulation of 
Tenant's business, such as Hazardous Materials storage fees for Tenant's 
Hazardous Materials, but not including any charges, levies or fees relating 
to the remediation or investigation of soil or groundwater or any other 
environmental response costs (except to the extent such items are caused by 
Tenant's use of Hazardous Materials); and (iii) all costs and fees (including 
attorneys' fees) incurred by Landlord in contesting any Real Property Taxes 
and in negotiating with public authorities as to any Real Property Taxes.  If 
at any time during the lease term the taxation or assessment of the Project 
prevailing as of the Commencement Date shall be altered so that in lieu of or 
in addition to any 


                                       11
<PAGE>

Real Property Taxes described above there shall be levied, assessed or 
imposed (whether by reason of a change in the method of taxation or 
assessment, creation of a new tax or charge, or any other cause) an 
alternate, substitute, or additional tax or charge (i) on the value, use or 
occupancy of the Project, (ii) on or measured by the gross receipts, income, 
or rentals from the Project, or on Landlord's business of leasing the 
Project, or (iii) computed in any manner with respect to the operation of the 
Project, then any such tax or charge, however designated, shall be included 
within the meaning of the term "Real Property Taxes" for purposes of the 
Lease.  If any Real Property Tax is based upon property or rents unrelated to 
the Project, then only that part of such Real Property Tax that is fairly 
allocable to the Project shall be included within the meaning of the term 
"Real Property Taxes."  Notwithstanding the foregoing, the term "Real 
Property Taxes" shall not include estate, inheritance, transfer, gift or 
franchise taxes of Landlord or the federal or state net income tax imposed on 
Landlord's income from all sources, or any tax, lien or charge imposed upon 
or assessed against the Project as a result of any Hazardous Material (as 
defined in Paragraph 6.3(a) below) condition on or about the Project, except 
to the extent such condition results from Hazardous Materials brought onto 
the Project by, or at the direction of, Tenant or Tenant's employees, agents, 
contractors, invitees or subtenants.

               (c)  Tenant's liability to pay Real Property Taxes shall be 
prorated on the basis of a 365-day year to account for any fractional portion 
of a fiscal tax year included in the Lease term at the commencement or 
expiration of the term.

               (d)  If Landlord's lender requires Landlord to pay any or all 
Real Property Taxes into an impound account on a periodic basis during the 
term of this Lease, Tenant, on notice from Landlord indicating this 
requirement, shall pay a sum of money toward its liability under Paragraph 
5.2 to Landlord on a periodic basis in accordance with the lender's 
requirements.

               (e)  Tenant, at its cost, shall have the right at any time to
seek a reduction in or otherwise contest any taxes for which it is obligated to
reimburse Landlord pursuant to this Paragraph 5, by action or proceeding against
the entity with authority to assess or impose the same.  Landlord shall not be
required to join in any proceeding or action brought by Tenant unless the
provisions of applicable law require that such proceeding or action be brought
by or in the name of Landlord, in which event Landlord shall join in such
proceeding or action or permit it to be brought in Landlord's name, provided
that Tenant shall pay all costs arising in connection therewith and shall
protect, indemnify, and hold Landlord free and harmless from and against any
liability, cost or expense in connection with such proceeding or consent. 
Tenant shall continue, during the pendency of such proceeding or action, to pay
the taxes due as determined by Landlord pursuant to this Paragraph 5.  If Tenant
is successful in such action or proceeding, Landlord shall reimburse to Tenant
Tenant's Share of the reduction in taxes realized by Tenant in such contest or
proceeding within ten (10) days after the amount of any refund has been received
by Landlord. 

     6.   USE.

          6.1  PERMITTED USES.  The premises shall be used and occupied only 
for the following purposes:  office, research and development, pharmaceutical 
manufacturing and warehousing, and other legal uses related to the uses 
described above, and for no other use or purpose.  Landlord does not make any 
warranty to Tenant regarding the suitability of the premises, or the 
suitability of the Building electrical and other systems servicing the 
premises, for Tenant's intended use thereof, and this Lease shall not be 
construed to imply any such warranty.


                                       12
<PAGE>

          6.2  COMPLIANCE WITH LAW.

               (a)  Landlord shall complete Landlord's Work (as defined in
Paragraph 34.1(a))in accordance with all applicable building codes and other
applicable law and regulations.

               (b)  Except as provided in Paragraph 6.2(a), Tenant shall accept
possession of the premises "as is" in their condition existing as of the date of
completion of Landlord's Work and Tenant acknowledges that neither Landlord nor
its agents has made any representations to Tenant regarding the condition of the
premises.  Landlord shall have no obligation to make any alterations,
improvements, or repairs to the premises unless otherwise expressly required in
this Lease.  Tenant acknowledges that its possession and use of the premises is
subject to all applicable laws, ordinances, codes, rules, orders, directions and
regulations of lawful governmental authority regulating the use or occupancy of
the premises, and all matters disclosed by any exhibits attached hereto
(collectively called "regulations").  Tenant, at Tenant's sole expense, shall
promptly comply with all such regulations as may now or hereafter be in effect
relating to or affecting the condition, use or occupancy of the premises, except
that Tenant shall not be required to make changes to structural elements of the
premises except to the extent the requirement to make such changes results from
Tenant's improvements to or particular use of the premises.

          6.3  HAZARDOUS MATERIALS.

               (a)  As used herein, "Hazardous Materials" means any substance or
material which is now or hereafter regulated by any local, state or federal
governmental entity due to its dangerous, hazardous, toxic, flammable or
corrosive characteristics.

               (b)  Tenant shall not cause or permit any Hazardous Materials to
be released from or about the Project, including, without limitation, releases
into the groundwater, soils or air underlying, adjacent to or in the vicinity of
the Project.  Tenant's use of Hazardous Materials in full compliance with:  (i)
validly issued governmental permits or authorizations, or (ii) applicable laws,
regulations or ordinances shall not violate the prohibition of the immediately
preceding sentence.  Tenant shall, prior to the execution hereof, advise
Landlord, after reasonable investigation, whether any of the Hazardous Materials
Tenant anticipates using in the premises are of the kind described as currently
present on or about the Project in the environmental reports delivered to Tenant
by Landlord pursuant to Paragraph 6.3(e) below.  On or about each anniversary of
the Commencement Date, Tenant shall also provide Landlord with an updated
written report setting forth any additional Hazardous Materials which Tenant
uses or stores on the Project.  The notification obligations set forth in the
immediately preceding sentence shall not apply to Tenant's use of typical office
products or occasional use of de minimis amounts of Hazardous Materials, but
shall include Hazardous Materials Tenant intends to regularly use in its
operations on the premises.  

               (c)  Tenant, at its sole expense shall comply with all applicable
governmental rules, regulations, codes, ordinances, statutes, directives and
other requirements (collectively, "Laws") respecting Hazardous Materials brought
on the Project by, or at the direction of, Tenant or Tenant's employees, agents,
contractors, invitees or subtenants.  Tenant, at its sole cost, shall perform
all investigations, clean-up and other response actions which may be required of
Tenant by any governmental authority in, on, or about the Project resulting from
Hazardous Materials brought on the Project by, or at the direction of, Tenant or
Tenant's employees, agents, contractors, invitees or subtenants.  


                                       13
<PAGE>

               (d)  Tenant shall indemnify, protect, defend (by legal counsel
subject to Landlord's approval, which shall not unreasonably be withheld) and
hold harmless Landlord from and against all costs (including, but not limited
to, environmental response costs), expenses, claims, judgments, losses, damages,
demands, liabilities, causes of action, governmental directives, proceedings or
hearings, including Landlord's attorneys and experts' fees and costs, relating
to or arising in connection with the use, handling, generation, storage,
transportation, release or disposal of Hazardous Materials brought on the
Project by, or at the direction of, Tenant or Tenant's employees, agents,
contractors, invitees or subtenants and/or relating to the breach of any of
Tenant's obligations under this Paragraph 6.3.  Tenant shall reimburse Landlord
for (i) losses in or reductions to rental income, (ii) all costs of clean-up or
other alterations to the premises, the Building or the Project, and (iii) any
diminution in the fair market value of the Project caused by Tenant's use,
handling, generation, storage, transportation, release or disposal of Hazardous
Materials brought on the Project by, or at the direction of, Tenant or Tenant's
employees, agents, contractors, invitees or subtenants.  The indemnity
obligations of Tenant set forth in Paragraph 6.3(d) shall control and supersede
any other indemnity obligations set forth in this Lease with respect to the use
of Hazardous Materials by Tenant, or its agents, contractors or invitees.

               (e)  Landlord and Tenant acknowledge that certain Hazardous
Materials are present on or about the premises as set forth in written reports
delivered by Landlord to Tenant prior to the execution of this Lease, which
reports are described on Exhibit C attached hereto.  The parties further
acknowledge that General Instrument Corporation, a Delaware corporation
("General Instrument"), is undertaking certain remediation of Hazardous
Materials in the vicinity of the premises pursuant to the requirements of
governmental agencies and the terms of that certain Environmental Undertakings
and Indemnity (the "Indemnity") dated December 1, 1995, by and between General
Instrument and Master Landlord.  Landlord and Tenant acknowledge that the
Indemnity provides General Instrument shall indemnify, defend and hold harmless
any person who acquires any portion of the premises, including such acquiring
parties' lessees, from certain costs related to Hazardous Materials.  Landlord
and Tenant further acknowledge their mutual intent that each party shall be a
direct beneficiary of the Indemnity.  Landlord and Tenant have jointly
determined to seek certain clarifications from General Instrument regarding the
status of third party beneficiaries under the Indemnity.  Landlord shall use due
diligence and reasonable efforts to obtain such clarifications in a form
reasonably acceptable to Tenant on or before December 1, 1996.  A copy of the
Indemnity has been provided by Landlord to Tenant prior to the execution of this
Lease, and Tenant acknowledges receipt and review of the Indemnity.  Landlord
makes no representation regarding the enforceability or efficacy of the
Indemnity, and any reliance thereon by Tenant shall be at Tenant's sole
discretion and risk.  Tenant acknowledges and agrees that General Instrument's
performance of the remediation and monitoring of Hazardous Materials in the
vicinity of the premises will require General Instrument to have access to
certain locations in the Outside Areas.  Tenant hereby grants such access to
General Instrument and its consultants and contractors to perform necessary
remediation and monitoring of Hazardous Materials in the vicinity of the
premises in accordance with requirements of all governmental agencies with
applicable jurisdiction, provided that General Instrument and its consultants
and contractors shall use due diligence to exercise such rights in a manner
which shall not unreasonably interfere with Tenant's use of the premises. 
Landlord and Tenant shall each immediately notify the other in writing upon
becoming aware of any other environmental investigation, clean-up or other
environmental response action or any claim or action requested, demanded,
instituted or to be instituted by any person, including but not limited to a
governmental entity, relating to any release or migration of Hazardous Materials
on, in, beneath, or adjacent to the Project.


                                       14
<PAGE>

               (f)  Landlord shall have the right, but not the obligation, in
its sole discretion, to conduct any Hazardous Materials inspections of the
premises, the Building or the Project.  Except in the event of an emergency
situation, Landlord shall give Tenant forty-eight (48) hours advance notice of
any such inspection and such inspection shall be conducted during normal
business hours.  When conducting any such inspections, Landlord shall avoid
unreasonably disrupting Tenant's activities.  Tenant shall provide Landlord with
reasonable cooperation to facilitate any such inspection by Landlord, its agents
or representatives.  Tenant shall not conduct any Hazardous Materials
investigation on or about the Project which includes any form of drilling or
subsurface penetration or any structural modifications without the prior written
consent of Landlord, which shall not be unreasonably withheld.

               (g)  Under no circumstances shall Tenant install, temporarily or
permanently, any underground or below-floor tanks, sumps or floor drains
relating to the use, storage or disposal of Hazardous Materials, without
Landlord's prior written approval, which shall not be unreasonably withheld,
which should not be unreasonably withheld.

               (h)  Upon either (i) the expiration or earlier termination of the
Lease term, or (ii) Landlord's reasonable determination, after consultation with
Landlord's environmental consultant, that Tenant may have released Hazardous
Materials on or about the Project, Tenant, at Tenant's sole cost, shall engage
the services of a qualified environmental engineering firm reasonably acceptable
to Landlord to determine whether any Hazardous Materials have been released by
Tenant on or about the Project.  The manner and scope of such examination shall
be reasonably approved by both Tenant and Landlord.  If any Hazardous Materials
contamination is discovered on or about the Project which has been caused by
Tenant, Tenant shall undertake all investigative and remedial action required to
remediate any contamination by Hazardous Materials caused by Tenant, or its
agents, contractors or invitees in a manner reasonably satisfactory to Landlord
and any governmental agency with jurisdiction over the Project.  Tenant agrees
that it shall be reasonable for Landlord to withhold its approval of any
investigative or remedial actions undertaken by Tenant unless such actions are
completed by Tenant with the effect that Landlord shall not be subject to any
losses, costs or further liabilities with respect to any Hazardous Materials
contamination which was caused by Tenant.

               (i)  Landlord shall indemnify, protect, defend (by legal counsel
subject to Tenant's approval, which shall not unreasonably be withheld) and hold
harmless Tenant from and against all costs (including, but not limited to,
environmental response costs), expenses, claims, judgments, losses, damages,
demands, liabilities, causes of action, governmental directives, proceedings or
hearings, including Tenant's attorneys and experts' fees and costs, relating to
or arising in connection with:  (i) the use, handling, generation, storage,
transportation, release or disposal of Hazardous Materials by Landlord, its
employees, agents, invitees or contractors, on, in, beneath, about or from the
Project, and/or relating to the breach of any of Landlord's obligations under
this Paragraph 6.3, and (ii) the release, migration or disposal of Hazardous
Materials on, in, beneath, about or from the Project which results from the acts
or omissions of any third party, which occurs prior to or during the Term or any
Extended Term of this Lease ("Claims").  The indemnification obligations of
Landlord set forth in the immediately preceding sentence shall:  (iii) terminate
with respect to costs of defense upon Landlord's expenditure of One Million
Dollars ($1,000,000) in connection with Landlord's performance of such
obligations, and shall terminate with respect to the remaining indemnification
obligations upon Landlord's expenditure of Two Million Five Hundred Thousand
Dollars ($2,500,000) in connection with Landlord's performance of such
obligations, (iv) not require Landlord to expend in excess of Fifty Thousand
Dollars ($50,000) in any calendar month in connection with the performance of
such obligations (although obligations in excess of Fifty Thousand Dollars
($50,000) per month shall be paid to Tenant in subsequent months with interest
at the rate of ten 


                                       15
<PAGE>

percent (10%) per annum, until such obligations are satisfied or until the 
limits in the prior clause are exceeded, which ever comes first), (v) not be 
binding on any independent third party lender of Landlord, in which Landlord 
has no economic interest, under a loan secured by Landlord's interest in the 
Project, in the event such third party lender acquires Landlord's interest in 
the Project through exercise of such Lender's loan remedies or receipt of a 
deed in lieu of exercise of such remedies, and (vi) be applicable only to 
Hazardous Materials conditions on or about the Project which originate or 
occur prior to or during the period of ownership of the Project by the 
individuals or entities which then comprise Landlord.  Landlord shall be 
entitled to retain legal counsel (subject to Tenant's approval, not to be 
unreasonably withheld) to jointly defend Landlord and Tenant from any Claim, 
so long as Landlord has acknowledged its obligation to indemnify Tenant 
without any reservation of rights, and if Tenant desires separate 
representation in connection with the defense of such Claim, the cost of such 
defense shall be paid by Tenant.  Notwithstanding the provisions of this 
Paragraph 6.3(i) above to the contrary, Landlord's indemnification 
obligations set forth above shall be reduced: (vii) to the extent Landlord is 
prejudice or damaged by any failure of Tenant to perform its notification 
obligations regarding Tenant's use of Hazardous Materials set forth in 
Paragraph 6.3(b) above, and (viii) in an amount equal to any default by 
Tenant in the payment of Base Rent pursuant to the provisions of Paragraph 
3.1 above, during the period any such amount remains in default.  

               (j)  To the extent any of the other provisions of this Lease
conflict with the provisions of this Paragraph 6.3, the provisions of this
Paragraph 6.3 shall be controlling.  The obligations of Landlord and Tenant
under this Paragraph 6.3 shall survive the expiration or earlier termination of
the Lease term.

          6.4  RESTRICTIONS ON USE.  Tenant shall not use or permit the use 
of the premises in any manner that will tend to create waste on the premises 
or constitute a nuisance to any other occupant or user of the Building or any 
neighboring building.  No materials or articles of any nature shall be stored 
or treated upon any portion of the Outside Areas unless located within an 
enclosure approved by Landlord, such approval not to be unreasonably withheld.

     7.   DIRECT OPERATING EXPENSES.

          7.1  LANDLORD TO MAINTAIN AND CONTROL OUTSIDE AREAS.  Landlord 
shall maintain the Outside Areas, together with all facilities and 
improvements now or hereafter located thereon, and together with all street 
improvements or other improvements adjacent thereto as may be required from 
time to time by governmental authority.  The manner in which such areas shall 
be maintained shall be reasonably determined by Landlord, subject to Tenant's 
approval, which shall not be unreasonably withheld. Landlord shall at all 
times have exclusive control of the Outside Areas and may at any time 
temporarily close any part thereof, may exclude and restrain anyone from any 
part thereof (except the bona fide customers, employees and invitees of 
Tenant who use the Outside Areas in accordance with the rules and regulations 
that Landlord may from time to time promulgate), and Landlord may change the 
configuration of the Outside Areas or the location of facilities thereon so 
long as any such change by Landlord does not unreasonably interfere with 
Tenant's use of the premises, the parking improvements or any storage or 
treatment area approved by Landlord under Paragraph 6.4.  Landlord shall also 
be entitled to employ third parties to operate and maintain all or any part 
of such areas on such terms and conditions as Landlord shall reasonably 
determine.  The surface parking facilities shall be available for the 
automobiles of Tenant and Tenant's customers, employees and invitees on an 
assigned, exclusive basis, in the locations set forth on Exhibit A attached 
hereto.  In exercising any such rights, Landlord shall make a reasonable 
effort to minimize any disruption of Tenant's business.


                                       16


<PAGE>


     7.2 TENANT TO PAY. Tenant shall pay Tenant's Share of such reasonable
costs and expenses as may be paid or incurred by Landlord in maintaining,
operating and repairing the Outside Areas and such adjacent areas referred
to in Paragraph 7.1 (hereinafter referred to as the "Direct Operating
Expenses") during the term of this Lease.  The Direct Operating Expenses
may include, without limitation, the cost of labor, equipment rental,
materials, supplies and services used or consumed in maintaining, operating
and repairing the Outside Areas and such adjacent areas referred to in
Paragraph 7.1, including without limitation, the following:  (a) landscaping
maintenance and replacement; (b) cleaning and repairing concrete walkways and
patios; (c) sweeping and repairing paved parking areas; (d) operating and
maintaining the parking and landscaping pole lighting, if any; (e) maintaining
all directional and security signs; (f) furnishing water for landscaping;
(g) pest control service (exterior only); and (h) security patrol service,
if any is provided by Landlord.

Notwithstanding the foregoing provisions of this Paragraph 7.2, the following
shall not be included within Direct Operating Expenses:  (i) leasing
commissions, attorneys' fees, costs, disbursements, and other expenses incurred
in connection with negotiations or disputes with tenants, or in connection with
leasing, renovating, or improving space for tenants or other occupants or
prospective tenants or other occupants of the Building, (ii) the cost of any
service sold to any other tenant or other occupant for which Landlord is
entitled to be reimbursed as an additional charge or rental over and above the
basic rent and escalations payable under the lease with that tenant, (iii) any
depreciation on the Building or Project, (iv) costs of a capital nature,
including but not limited to capital improvements and alterations, capital
repairs, capital equipment, and capital tools as determined in accordance with
generally accepted accounting principles, provided, however, that Landlord shall
be permitted to charge Tenant for the costs of such capital items to the extent
such costs are amortized by Landlord over the useful life of such improvements,
as reasonably determined by Landlord, in accordance with generally accepted
accounting principles, (v) expenses in connection with services or other
benefits of a type that are not provided to Tenant but which are provided
another tenant or occupant of the Building or Project, (vi) costs incurred due
to Landlord's violation of any terms or conditions of this Lease or any other
lease relating to the Building or Project, (vii) overhead profit increments paid
to Landlord's subsidiaries or affiliates for management or other services on or
to the Building or for supplies or other materials to the extent that the cost
of the services, supplies, or materials exceeds the cost that would have been
paid had the services, supplies, or materials been provided by unaffiliated
parties on a competitive basis, (viii) all interest, loan fees, and other
carrying costs related to any mortgage or deed of trust, and all rental and
other amounts payable under any ground or underlying lease, or any lease for any
equipment ordinarily considered to be of a capital nature (except janitorial
equipment which is not affixed to the Building), (ix) any compensation paid to
clerks, attendants, or other persons in commercial concessions operated by
Landlord, (x) advertising and promotional expenditures, (xi) costs of repairs
and other work occasioned by fire, windstorm, or other casualty of an insurable
nature, to the extent Landlord receives proceeds from insurance required to be
carried under this Lease, (xii) any costs, fines, or penalties incurred due to
violations by Landlord of any governmental rule or authority, this Lease or any
other lease in the Project, or due to Landlord's negligence or willful
misconduct, (xiii) management costs to the extent they exceed management costs
charged for similar facilities in the area and in any event, to the extent they
exceed 5% of all other Direct Operating Expenses, (xiv) costs for sculptures,
paintings or other objects of art (nor insurance thereon or extraordinary
security in connection therewith, (xv) wages, salaries, or other compensation
paid to any executive employees above the grade of building manager, and (xvi)
the cost of containing, removing, or otherwise remediating any contamination of
the Project (including the underlying land and ground water) by any Hazardous
Materials, where such contamination was not caused by Tenant, its agents,
employees, invitees or contractors.


                                     17

<PAGE>



          7.3  MONTHLY PAYMENTS.  Tenant shall pay to Landlord on the first
day of each calendar month during the twelve (12) month period immediately
following the Rent Commencement Date an amount estimated by Landlord to be
one-twelfth of Tenant's Share of the Direct Operating Expenses for such
twelve (12) month period.  During each one (1) year period after the initial
year following the Rent Commencement Date, Tenant shall pay to Landlord on the
first day of each calendar month thereof in advance one-twelfth of Tenant's
Share (to the nearest $5.00) of the actual Direct Operating Expenses for the
one (1) year period immediately prior thereto.  Within sixty (60) days following
the anniversary of the Rent Commencement Date Landlord shall furnish Tenant a
statement covering such period and the payments made by Tenant with respect to
such period as set forth in this Paragraph 7.3.  If Tenant's payments for said
Direct Operating Expenses did not equal the actual amount of said Direct
Operating Expenses, Tenant shall pay to Landlord the deficiency within
ten (10) days after  receipt of such statement.  If said payments exceed
the actual Direct Operating Expenses, Landlord shall either credit the excess
against payments next thereafter to become due to Landlord pursuant to this
Paragraph 7.3, or refund the amount of the overpayments to Tenant, in cash, as
Landlord shall elect.  Direct Operating Expenses shall be prorated as of the
Rent Commencement Date and the Expiration Date (or the date of any sooner
termination of the term of this Lease) to reflect the portion of the payment
period occurring within the lease term.  Within 90 days after receipt of
Landlord's statement setting forth actual Direct Operating Expenses (the
"Statement"), Tenant shall have the right to audit at Landlord's local offices,
at Tenant's expense, Landlord's accounts and records relating thereto.  Such
audit shall be conducted by a certified public accountant approved by Landlord,
which approval shall not be unreasonably withheld.  If such audit reveals that
Landlord has overcharged Tenant, the amount overcharged shall be paid to Tenant
within thirty (30) days after the audit is concluded, together with interest
thereon at the rate of  ten percent (10%) per annum, from the date such amounts
were paid by Tenant until payment of the overcharge is made to Tenant.  In
addition, if the Statement exceeds the actual Direct Operating Expenses which
should have been charged to Tenant by more than five percent (5%) the cost of
the audit shall be paid by Landlord.

     8.   MAINTENANCE AND REPAIRS.  

          8.1  TENANT'S OBLIGATIONS.  Except as provided in Paragraphs
6.2(a), 8.2, 15, and 16, Tenant shall, at Tenant's expense, keep in good and
safe condition, order and repair the premises and every part thereof,
including without limitation, all plumbing, heating, air conditioning,
ventilating, fire sprinklers, electrical and lighting facilities, systems,
appliances, and equipment within the premises; and all fixtures, interior
walls, interior surfaces of exterior walls, floors, ceilings, windows, doors,
entrances, all glass (including plate glass), and skylights located within
the premises and the roof membrane installed over the premises.  Tenant shall,
at Tenant's expense, maintain in full force at all times during the term of
this Lease a heating, ventilating and air conditioning ("HVAC") systems 
preventive maintenance contract with a qualified service company satisfactory
to Landlord covering all HVAC systems servicing the premises, which
shall provide for and include, without limitation, replacement of filters,
oiling and lubricating of machinery, parts replacement, adjustment of drive
belts, oil changes, weatherproofing of all exposed HVAC equipment and ducts, and
other preventive maintenance; provided, however, that Tenant shall have the
benefit of all warranties available regarding the equipment in said systems. 
Said contract shall call for periodic servicing no less than every sixty (60)
days.  Tenant shall be permitted to provide the above described HVAC maintenance
services through a qualified employee of Tenant in lieu of a third party
contractor.  Tenant shall also maintain continuously throughout the lease term a
service contract for the washing of all windows of the premises (both interior
and exterior surfaces) with a contractor approved by Landlord which provides for
the periodic washing of all such windows sufficiently often that such windows
remain clean.  Tenant shall furnish Landlord with copies of all such service


                                      18

<PAGE>


contracts, which shall provide that they may not be cancelled or changed without
at least thirty (30) days prior written notice to Landlord.  All repairs
required to be made by Tenant shall be made promptly with new materials of like
kind and quality.  If the repair work affects the structural parts of the
Building, or if the estimated cost of any item of repair exceeds $25,000, then
Tenant shall first obtain Landlord's written approval of the scope of work,
plans therefor, materials to be used, and the contractor.  Tenant hereby waives
the benefit of any statute now or hereafter in effect which would otherwise
afford Tenant the right to make repairs at Landlord's expense or to terminate
this Lease because of Landlord's failure to keep the premises in good condition,
order and repair.  Tenant specifically waives all rights it may have under
Sections 1932(1), 1941, and 1942 of the California Civil Code, and any similar
or successor statute or law.

          8.2  LANDLORD'S OBLIGATIONS.  Landlord shall, at Landlord's expense,
keep in good condition, order and repair the foundation and exterior walls of
the Building (excluding the interior of all walls and the exterior and interior
of all windows, doors, plate glass, and show cases), and the structural portions
(but not the membrane) of the roof of the Building (except that Tenant shall
repair at Tenant's expense any damage caused by the activities of Tenant,
Tenant's HVAC maintenance service contractor, and/or Tenant's other agents on
the roof, including but not limited to the installation of air conditioning
equipment and/or duct work, or other roof penetrations, and improper flashing
or caulking, and any damage to exposed air conditioning equipment and duct-work
installed by or for Tenant).  Landlord shall exercise reasonable diligence in
performing such repairs as soon as practicable.  Landlord shall promptly make
repairs under this Paragraph 8.2 after Landlord's receipt of written notice
from Tenant of the need for such repairs.  Except as otherwise specifically
provided herein, there shall be no abatement of rent or other sums payable by
Tenant prior to or during any repairs by Tenant or Landlord, and Tenant waives
all claims for loss of business or lost profits relating to any such repairs.
Notwithstanding the provisions of Paragraph 7.1 or this Paragraph 8.2 above to
the contrary, in the event, and at such time as, Tenant leases the entire
Building, all maintenance and repair obligations of Landlord shall terminate,
and all maintenance, repair and replacement obligations of Landlord set forth
in this Lease, including the obligation under Paragraph 7.1 above with respect
to maintenance and repair of the Outside Areas, shall be assumed and performed
by Tenant, at its sole cost. 

     9.  ALTERATIONS.

          9.1  LANDLORD'S CONSENT REQUIRED.  Tenant shall not, without
Landlord's prior written consent, which shall not be unreasonably withheld,
make any alterations, improvements, additions, or utility installations
(collectively called "alterations") in, on or about the premises, except
for nonstructural alterations with a cost equal to or less than
Twenty-Five Thousand Dollars ($25,000).  As used in this Paragraph 9.1,
the term "utility installation" means power panels, wiring, fluorescent
fixtures, space heaters, conduits, air conditioning and plumbing.  Should 
Tenant make any alterations requiring the prior written consent of Landlord
without obtaining such consent, Tenant shall immediately remove the same at
Tenant's expense upon demand by Landlord.


                                      19

<PAGE>


          9.2  PLANS AND PERMITS.  Any alteration that Tenant shall desire to
make in or about the premises and which requires the consent of Landlord shall
be presented to Landlord in written form, with proposed detailed plans and
specifications therefor prepared at Tenant's sole expense.  Any consent by
Landlord thereto shall be deemed conditioned upon Tenant's acquisition of all
permits required to make such alteration from all appropriate governmental
agencies, the furnishing of copies thereof to Landlord prior to commencement
of the work, and the compliance by Tenant with all conditions of said permits
in a prompt and expeditious manner, all at Tenant's sole expense.  Upon
completion of any such alteration, Tenant, at Tenant's sole cost, shall
immediately deliver to Landlord "as-built" plans and specifications therefor.

          9.3  CONSTRUCTION WORK DONE BY TENANT.  All construction work
required or permitted to be done by Tenant, including that work which Tenant is
required to complete prior to the Rent Commencement Date (as described in
Paragraph 34 below), shall be performed by licensed contractors reasonably
acceptable to Landlord in a prompt, diligent, and good and workmanlike manner,
and shall not diminish the value of the Building.  All such construction work
shall be performed in compliance with all applicable statutes, ordinances,
regulations, codes and orders of governmental authorities and insurers of the
premises.  Tenant or its agents shall obtain and pay for all licenses and
permits necessary therefor.

          9.4  ROOF REPAIRS.  All installation of air conditioning equipment
and duct work requiring penetration of the roof shall be properly flashed
and caulked.  Any equipment placed by Tenant on the roof shall be elevated
and supported by Tenant so as not to inhibit drainage or Landlord's repair
of the roof pursuant to Paragraph 8.2. 

          9.5  TITLE TO ALTERATIONS.  During the term of the Lease, improvements
to the premises and the Project made by Tenant at Tenant's expense shall be the
property of Tenant.  Unless Landlord requires the removal thereof as set forth
in Paragraphs 9.1 or 9.6, any alterations which may be made on the premises
shall remain upon and be surrendered with the premises at the expiration or
sooner termination of the term of this Lease, and shall become the property
of Landlord at that time.  Without limiting the generality of the foregoing,
all heating, lighting, electrical (including all wiring, conduits, main and
subpanels), air conditioning, partitioning, drapery, and carpet installations
made by Tenant, regardless of how affixed to the premises, together with all
other alterations that have become an integral part of the premises, shall
not be deemed trade fixtures, and shall remain upon and be surrendered with
the premises at the expiration or sooner termination of this Lease, and shall
become the property of the Landlord at that time.  Notwithstanding the
provisions of this Paragraph 9.5 above, Tenant's furnishings, machinery and
equipment, other than that which is affixed to the premises so that it cannot
be removed without material damage to the premises, shall remain the property
of Tenant and may be removed by Tenant, provided Tenant at Tenant's expense
immediately after removal repairs any damage to the premises caused thereby.

          9.6  REMOVAL OF ALTERATIONS.  Landlord may elect, by notice to Tenant
given in the same notice by which Landlord consents to the installation of any
alteration by Tenant, to require Tenant to remove such alterations and to
restore the premises as hereafter provided.  If Landlord so elects, Tenant
shall, at its sole expense, upon expiration of the Lease term or within twenty
(20) days after any sooner termination thereof, remove such alterations, repair
any damage occasioned thereby, and restore the premises to the condition
existing as of the completion of the Tenant Improvements.  The obligations of
Tenant set forth in this paragraph shall survive the termination of this Lease.


                                   20

<PAGE>

    10. MECHANICS' LIENS.  Tenant shall keep the premises, the Building, and the
Project free from any liens arising out of any work performed, materials 
furnished or obligations incurred by Tenant.  In the event that Tenant shall 
not, within ten (10) days following the imposition of any such lien, cause the 
same to be released of record, Landlord shall have, in addition to all other 
remedies provided herein and by law, the right, but no obligation, to cause the 
same to be released by such means as Landlord shall deem proper, including 
payment of the claim giving rise to such lien.  All sums paid by Landlord for 
such purpose, and all expenses incurred by it in connection therewith, shall be 
payable to Landlord by Tenant on demand with interest at the rate of fifteen 
percent (15%) per annum, or the maximum rate permitted by law, whichever is 
less.  Tenant shall give Landlord notice of the date of commencement of any 
work in the premises not less than ten (10) days prior thereto, and Landlord 
shall have the right to post notices of non-responsibility or similar notices 
in or on the premises in connection therewith.

    11. UTILITIES.  Commencing upon the Commencement Date, Tenant shall pay when
due directly to the charging authority all charges for water, gas, electricity,
telephone, refuse pickup, janitorial services, and all other utilities and 
services supplied or furnished to the premises together with any taxes thereon.
In no event shall Landlord be liable to Tenant for failure or interruption of 
any such utilities or services, unless caused by the negligence or willful 
misconduct of or breach of this Lease by Landlord, and no such failure or 
interruption shall entitle Tenant to terminate this Lease or to withhold rent or
other sums due hereunder.  In the event Landlord anticipates that any planned 
actions of Landlord may interrupt utility services to the premises, Landlord 
shall provide Tenant with reasonable advance notice to permit Tenant to monitor 
such action and to make any necessary preparations for any interruption in 
utility services.  Landlord shall not be responsible for providing security 
guards or other security protection for all or any portion of the premises, 
and Tenant shall at its own expense provide or obtain such security services 
as Tenant shall desire to insure the safety of the premises. 

    12. INDEMNITY.  Each party (the "Indemnifying Party") shall indemnify, 
protect, defend, and hold harmless the other party (the "Non-Indemnifying 
Party") from and against any and all claims, damages, losses, proceedings, 
causes of action, costs, expenses or liabilities due to, but not limited to,
bodily injury, including death resulting at any time therefrom, and/or 
property damage, now or hereafter arising from any act, work or things done or 
permitted to be done or otherwise suffered, or any omission in or about the 
premises, the Building, or the Project, by the Indemnifying Party or by any of 
the Indemnifying Party's agents, employees, contractors, or invitees, or from 
any breach or default by the Indemnifying Party in the performance of any 
obligation on the part of the Indemnifying Party to be performed under the terms
of this Lease, except to the extent such damage, loss, expense or liability is 
caused by the negligence or willful misconduct of or a breach of this Lease by 
the Non-Indemnifying Party or its employees, agents, contractor or invitees. 
The Indemnifying Party shall also indemnify the Non-Indemnifying Party from and 
against all damage, loss, expense (including without limitation, attorneys' 
fees, costs of investigation, and expert witness fees) and liability incurred or
suffered by the Non-Indemnifying Party in the defense of or arising out of or 
resulting from any claim or any action or proceeding brought thereon.  In the 
event any action or proceeding shall be brought against the Non-Indemnifying 
Party by reason of any such claim, the Indemnifying Party upon notice from the 
Non-Indemnifying Party shall defend the same at the Indemnifying Party's expense
with counsel reasonably satisfactory to the Non-Indemnifying Party.  The 
obligations of the Indemnifying Party contained in this paragraph shall survive 
the termination of this Lease.

    13. WAIVER OF CLAIMS.  Tenant hereby waives any claims against Landlord for 
injury to Tenant's business or any loss of income therefrom or for damage to the
goods, wares, merchandise or other property of Tenant, or for injury or death of
Tenant's agents, employees, invitees, or any other person in or about the 
premises, the Building, and the Project, from any 

                                       21

<PAGE>

cause whatsoever, regardless of whether the same results from conditions 
existing upon the premises or from other sources or places, and regardless 
of whether the cause of such damage or injury or the means of repairing the 
same is inaccessible to Tenant.  The above waiver shall not apply to any claims
based upon Landlord's breach of its obligations under this Lease or upon the 
negligence or willful misconduct of Landlord.  Nothing in this Paragraph 13 
shall prevent Tenant from making any claims or receiving any benefits under the 
insurance policies which are required to be maintained hereunder.   

      14. INSURANCE.

          14.1 TENANT'S LIABILITY INSURANCE.  Tenant shall, at its sole cost 
and expense, obtain and keep in force during the term of this Lease either 
Comprehensive General Liability insurance or Commercial General Liability 
insurance applying to the condition, use, occupancy, and maintenance of the 
premises and the business operated on the premises by Tenant, or any other 
party occupying the premises pursuant to a sublease, concession, license or 
similar agreement with Tenant.  Such insurance shall include Broad Form 
Contractual liability insurance coverage insuring all of Tenant's indemnity 
obligations under this Lease.  Such coverage shall have a minimum combined 
single limit of liability of at least Three Million Dollars ($3,000,000).  All 
such policies shall be written to apply to all bodily injury, property damage, 
personal injury and other  covered loss, however occasioned. All such policies 
shall be endorsed to add Landlord and any lender or other party named by 
Landlord as an additional insured and to provide that any insurance maintained 
by Landlord shall be excess insurance only.  Such coverage shall also contain 
endorsements:  (i) deleting any employee exclusion on personal injury coverage;
and (ii) including employees as additional insureds. All such insurance shall 
provide for severability of interests; shall provide that an act or omission of
one of the named insureds shall not reduce or avoid coverage to the other named 
insureds; and shall afford coverage for all claims based on acts, omissions, 
injury and damage, which claims occurred or arose (or the onset of which 
occurred or arose) in whole or in part during the policy period.  Tenant shall 
also maintain Workers' Compensation insurance in accordance with California law,
and employers liability insurance with a limit no less than One Million Dollars 
($1,000,000) per employee and One Million Dollars ($1,000,000) per occurrence.  
The limits of all insurance described in this Paragraph 14.1 shall not, however,
limit the liability of Tenant hereunder. Not more frequently than once each 
calendar year if, in the reasonable opinion of Landlord, the amount of insurance
required hereunder is not adequate, Tenant shall increase said insurance 
coverage as reasonably required by Landlord; provided that, in no event shall 
any such increase in coverage require Tenant to maintain insurance coverage 
which exceeds that which is customary and commercially reasonable for buildings
of similar type, use and location.  The failure of Landlord to require any 
additional insurance coverage at any time shall not relieve Tenant from the 
obligation to provide increased coverage at any later time or relieve Tenant 
from any other obligations under this Lease. 

         14.2 LANDLORD'S LIABILITY INSURANCE.  Landlord shall maintain a policy 
or policies of commercial general liability insurance insuring Landlord (and 
such other persons as may be designated by Landlord) against liability for 
personal injury, bodily injury or death and damage to property occurring or 
resulting from an occurrence in, on, or about the Project with a combined single
limit of not less than Three Million Dollars ($3,000,000), or such greater 
coverage as Landlord may from time to time determine is reasonably necessary for
its protection. 

         14.3 PROPERTY INSURANCE.

              (a) Landlord shall obtain and keep in force during the term of 
this Lease a policy or policies of insurance covering loss or damage to the 
Project, but excluding 

                                       22

<PAGE>


coverage of merchandise, fixtures, equipment and leasehold improvements and 
alterations (including the Tenant Improvements) of Tenant, in the amount of the
full replacement value thereof, providing protection against all perils included
within the classification of fire, extended coverage, vandalism, malicious 
mischief, special extended perils (all risk), including boiler and machinery
coverage and an inflation endorsement, and, at Landlord's option, flood and/or
earthquake.  Tenant's obligation to reimburse Landlord for insurance premiums 
attributable to flood and/or earthquake coverage shall not exceed an annual 
premium in an amount calculated at the rate of Three Thousand Five Hundred 
Dollars ($3,500) per each One Million Dollars ($1,000,000) of the value of 
Landlord's property to which such insurance is applicable, such limitation to 
be increased throughout the term of the Lease at a compounded annual interest 
rate of five percent (5%).  In addition, Landlord shall obtain and keep in 
force, during the term of this Lease, a policy of rental loss insurance covering
a period of one year, commencing on the date of loss, with proceeds payable to 
Landlord, which insurance may also cover all Real Property Taxes, Direct 
Operating Expenses, insurance premiums, and other sums payable by Tenant to 
Landlord hereunder for said period.  The insurance coverage may include 
sprinkler leakage insurance if the Building contains fire sprinklers.  Tenant 
shall have no interest in or right to the proceeds of any such insurance carried
by Landlord, except that Tenant may require Landlord to utilize proceeds of such
insurance to complete Landlord's repair and restoration obligations set forth 
herein.  Tenant shall have the right to reasonably approve the amount of any 
deductibles applicable to the insurance maintained by Landlord pursuant to this
Paragraph 14.3(a). 

              (b) Tenant shall, at Tenant's sole expense, obtain and keep in 
force during the term of this Lease, a policy of fire and extended coverage 
insurance including a standard "all risk" endorsement, insuring the inventory,
fixtures, equipment, personal property, and leasehold improvements and 
alterations of Tenant (including the Tenant Improvements) which are a part of 
or comprise the premises for the full replacement value thereof, as the same may
increase from time to time due to inflation or otherwise.  The proceeds from any
of such policies shall be used for Tenant's repair or replacement of such items
so insured and, provided such insurance proceeds are used for such repair and 
replacement, Landlord shall have no interest in such insurance proceeds.

         14.4 PAYMENT.  Tenant shall pay to Landlord Tenant's Share of the 
premium for the insurance obtained by Landlord pursuant to Paragraph 14.2.
Tenant shall pay to Landlord a share (the "Property Insurance Share") of 
the premium for the insurance obtained by Landlord pursuant to Paragraph 
14.3(a).  The Property Insurance Share shall be that percentage of the 
premium paid for such insurance by Landlord which is the percentage of 
coverage under such policy attributable to the improvements located in the
Outside Area and to any portion of the Building which is jointly used by or
provides joint benefits to both Landlord and Tenant (e.g., a boiler or utility
room) if any.  The Property Insurance Share shall be determined by Landlord and 
shall be subject to Tenant's approval, such approval not to be unreasonably 
withheld.  Tenant shall pay to Landlord the Property Insurance Share of the 
amount of any deductibles for claims under insurance obtained by Landlord under
Paragraph 14.3(a) relating to loss or damage to the Project from any peril 
(including flood and earthquake) covered by such insurance.  Notwithstanding the
preceding sentence, Tenant shall pay to Landlord the entire amount of any 
deductibles and other amounts not paid by Landlord's insurance carriers relating
to claims under Landlord's insurance policies resulting from the negligent acts 
or omissions of, or a breach of this Lease by, Tenant, or its agents, employees,
and invitees.  Notwithstanding the foregoing, Landlord may obtain liability 
insurance and property insurance for the Project separately, or together with 
other buildings and improvements under blanket policies of insurance.  In the 
latter  case Tenant shall be liable for only such portion of the premiums for 
such blanket policies as are allocable to the premises, as reasonably determined
by the insurer or Landlord.  Tenant shall pay such premiums and/or deductibles 
and other amounts to Landlord within thirty (30) days after 

                                       23

<PAGE>

receipt by Tenant of a copy of the premium statement or other reasonable 
evidence of the amount due. If the term of this Lease does not commence or 
expire concurrently with the commencement or expiration, respectively, of the
period covered by such insurance, Tenant's liability for premiums shall be 
prorated on an annual basis. 

         14.5 INSURANCE POLICIES. The insurance required to be obtained by 
Tenant pursuant to Paragraphs 14.1 and 14.3(b) shall be primary insurance and 
(a) shall provide that the insurer shall be liable for the full amount of the 
loss up to and including the total amount of liability set forth in the 
declarations without the right of contribution from any other insurance coverage
of Landlord, (b) shall be carried with companies mutually acceptable to Landlord
and Tenant, which shall be rated at least A VIII or better by Best's Insurance 
Guide, and (c) shall specifically provide that such policies shall not be 
subject to cancellation, reduction of coverage or other change except after at 
least thirty (30) days prior written notice to Landlord.  The policy or policies
required under this Paragraph 14, or duly executed certificates for them, 
together with satisfactory evidence of payment of the premium thereon, shall be
deposited with the non-maintaining party on or prior to the Commencement Date,
and upon each renewal of such policies, which shall be effected not less than 
thirty (30) days prior to the expiration date of the term of such coverage.  
Tenant shall not do or permit to be done anything which shall invalidate any of 
the insurance policies referred to in Paragraphs 14.1, 14.2, and 14.3.

         14.6 WAIVER OF SUBROGATION.  Tenant and Landlord each hereby waives any
and all rights of recovery against the other, or against the officers, 
employees, agents, partners and beneficiaries of the other, for loss of or 
damage to the property of the waiving party, or the property of others under its
control, to the extent of proceeds received as a result of such loss or damage 
under any insurance policy carried by Landlord or Tenant.  Tenant and Landlord 
shall, upon obtaining the policies of insurance required hereunder, give notice
to the insurance carrier or carriers that the foregoing mutual waiver is 
contained in this Lease. 

         14.7 NO LIMITATION OF LIABILITY.  Neither party makes any 
representation that the limits of liability specified to be carried by Tenant
or Landlord under the terms of this Lease are adequate to protect any party,
except that the parties shall use due diligence to assure that insurance 
coverages maintained hereunder are adequate to permit the parties to perform 
their respective repair and restoration obligations under this Lease.  If 
Tenant believes that the insurance coverage required under this Lease is 
insufficient to adequately protect Tenant, Tenant shall provide, at its own 
expense, such additional insurance as Tenant deems adequate. 

         14.8 IMPOUNDING OF PREMIUMS.  If Landlord's lender requires Landlord 
to pay insurance premiums into an impound account on a periodic basis during the
term of this Lease, Tenant, upon notice from Landlord indicating this 
requirement, shall pay a sum of money toward its liabilities under Paragraphs 
14.2 and 14.3(a) to Landlord on a periodic basis in accordance with the lender's
reasonable requirements. Landlord shall impound the insurance premiums received
from Tenant in accordance with the reasonable requirements of the lender.

                                       24

<PAGE>

    15. DAMAGE OR DESTRUCTION.

         15.1 PARTIAL DAMAGE-INSURED.  If the premises or the Building, as the 
case may be, are damaged to the extent of less than fifty percent (50%) of the 
then replacement value thereof (excluding excavations and foundations with 
respect to the Building), and if such damage was caused by an act or casualty 
covered under an insurance policy required to be maintained pursuant to 
Paragraph 14.3(a), and if the proceeds of such insurance received by Landlord 
are sufficient to repair the damage (less any deductible amounts payable under
such policy), and if Landlord is permitted, under all applicable laws, to 
restore the premises and/or the Building to their prior condition, Landlord 
shall at Landlord's expense repair such damage as soon as reasonably possible 
and this Lease shall continue in full force and effect.

         15.2 PARTIAL DAMAGE-UNINSURED.  Subject to the provisions of Paragraph 
15.3, if at any time during the term hereof the premises or the Building, as the
case may be, are damaged and the insurance proceeds received by Landlord are not
sufficient to repair such damage, or such damage was caused by an act or 
casualty not covered under an insurance policy required to be maintained by 
Landlord pursuant to Paragraph 14.3(a), Landlord may at Landlord's option either
(a) repair such damage as soon as reasonably possible at Landlord's expense, in 
which event this Lease shall continue in full force and effect, or (b) give 
written notice of termination of this Lease to Tenant within thirty (30) days 
after the date of the occurrence of such damage, with the effective date of 
such termination to be the date of the occurrence of such damage.  In the event 
Landlord gives such notice of termination of this Lease, Tenant shall have the 
right, within thirty (30) days after receipt of such notice, to agree in 
writing on a basis satisfactory to Landlord to pay for the entire cost of 
repairing such damage less only the amount of insurance proceeds, if any, 
received by Landlord, in which event the notice of termination shall be 
ineffective and this Lease shall continue in full force and effect, and Landlord
shall proceed to make such repairs as soon as reasonably possible.  If Tenant 
does not give such notice within such thirty (30) day period this Lease shall 
be terminated pursuant to such notice of termination by Landlord.  The 
conditions to Landlord's restoration obligation set forth in this Paragraph 
15.2 shall not be an excuse to Landlord's completion of such restoration 
obligations if the damage to the premises or the Building was caused by the 
negligence or willful misconduct of Landlord, its agents, contractors or 
invitees.  

         15.3 TOTAL DESTRUCTION. If at any time during the term hereof either 
the premises or the Building is destroyed to the extent of fifty percent (50%)
or more of the then replacement value thereof (excluding excavations and 
foundations with respect to the Building), from any cause whether or not 
covered by the insurance maintained by Landlord pursuant to Paragraph 14.3(a),
or if, regardless of the extent of the damage, Landlord is not permitted under
all applicable laws to restore the premises and/or the Building to the condition
which existed prior to the casualty, this Lease shall at the option of Landlord
terminate as of the date of such destruction.  Landlord shall exercise its right
to terminate this Lease by delivery of notice of termination to Tenant within 
thirty (30) days after the date that Tenant notifies Landlord of the occurrence
of such damage.  In the event Landlord does not elect to terminate this Lease, 
Landlord shall at Landlord's expense repair such damage as soon as reasonably 
possible, and this Lease shall continue in full force and effect.  In the event
Landlord terminates this Lease pursuant to the provisions of this Paragraph 
15.3, Tenant shall have the right, within thirty (30) days after Tenant's 
receipt of such notice of termination, to agree in writing on a basis reasonably
satisfactory to Landlord to pay for the entire cost of repair or restoration of 
the premises or Building, less only the amount of insurance proceeds available 
for such restoration, in which event the notice of termination shall be 
ineffective and this Lease shall continue in full force and effect and Landlord 
shall restore the premises and/or the Building as soon as reasonably possible.  

                                       25

<PAGE>

If Tenant does not give such notice with such thirty (30) day period, this Lease
shall be terminated pursuant to such notice of termination delivered by 
Landlord.

         15.4 DAMAGE NEAR END OF TERM.  Notwithstanding anything to the contrary
in Paragraph 15, if the premises or the Building, as the case may be, are 
destroyed or damaged in whole or in part during the last one (1) year of the 
Term of this Lease, such that the cost of repair would equal Fifty Thousand 
Dollars ($50,000) or more, whether from an insured or uninsured casualty,  
Landlord may at Landlord's option cancel and terminate this Lease as of the date
of occurrence of such damage by giving written notice to Tenant of Landlord's 
election to do so within thirty (30) days after the date of occurrence of such 
damage.  If any damage or destruction of the premises or the Building occurs 
within the last year of the Term or any Extended Term, and the period in which 
Tenant has the right to exercise its option to renew the Term or the Extended 
Term pursuant to Paragraph 33 below has not expired, Tenant shall have thirty 
(30) days following receipt of Landlord's notice of termination in which to 
notify Landlord if its election to exercise such renewal option, in which event
the foregoing provisions of this Paragraph 15 shall control Landlord and 
Tenant's rights in connection with cancellation of this Lease.  

         15.5 ABATEMENT OF RENT. Notwithstanding anything to the contrary 
contained in Paragraph 3 or elsewhere in this Lease, if the premises or the 
Building are partially damaged or totally destroyed and Landlord elects or is 
required to repair or restore them pursuant to the provisions of this Paragraph 
15, the rent, including Base Rent, Tenant's Share of Direct Operating Expenses,
Real Property Taxes, and insurance premiums, payable hereunder for the period 
commencing on the occurrence of such damage and ending upon completion of such 
repair or restoration shall be abated in proportion to the extent to which 
Tenant's use of the premises is impaired during the period of repair.  Except 
for abatement of rent, if any, Tenant shall have no claim against Landlord for 
any damage suffered by reason of any such damage, destruction, repair or 
restoration, unless caused by the negligence or willful misconduct of Landlord.

         15.6 WAIVER.  Tenant waives the provisions of California Civil Code 
Sections 1932(2) and 1933(4), and any similar or successor statutes relating to 
termination of leases when the thing leased is substantially or entirely 
destroyed, and agrees that any such occurrence shall instead be governed by the 
terms of this Lease. 

         15.7 TENANT'S PROPERTY. Landlord's obligation to rebuild or restore 
shall not include restoration of Tenant's trade fixtures, equipment, 
merchandise, or any improvements, alterations or additions (including the Tenant
Improvements) made by Tenant to the premises, which shall all be repaired, 
restored or replaced by Tenant at its sole cost.

         15.8 NOTICE OF DAMAGE. Tenant shall notify Landlord within five (5) 
days after the occurrence thereof of any damage to all or any portion of the 
premises.  In no event shall Landlord have any obligation to repair or 
restore the premises pursuant to this Paragraph 15 until a reasonable period 
of time after Landlord's receipt of notice from Tenant of the nature and scope 
of any damage to the premises, and a reasonable period of time to collect 
insurance proceeds arising from such damage (unless such damage is clearly not 
covered by insurance then in effect covering the premises).

         15.9 REPLACEMENT COST. The determination of Landlord (after 
consultation with Landlord's architect or contractor) of the estimated cost of 
repair of any damage, or of the replacement cost, shall be reasonably made by 
Landlord in good faith, and shall be conclusive for purposes of this Paragraph 
15.

                                       26

<PAGE>


         15.10     TENANT'S CANCELLATION RIGHT.  Upon any damage to or
destruction of the premises or the Building (if such Building damage materially
and adversely affects Tenant's use of the premises), Landlord shall, within
thirty (30) days following such casualty, advise Tenant in writing of the
estimated period required to complete Landlord's repair and restoration
obligations under this Paragraph 15.  Such estimate shall be reasonably made by
Landlord in good faith following consultation with Landlord's architect or
contractor.  If the estimated period required to complete Landlord's repair or
restoration obligations set forth in such notice exceeds one hundred eighty
(180) days from the date of such casualty, Tenant shall have the right, by
delivery of written notice to Landlord within fifteen (15) business days
following Tenant's receipt of such notice, to cancel this Lease.  Such
cancellation shall be effective upon delivery of such notice to Landlord. 
Notwithstanding anything to the contrary contained in this Paragraph 15.10, if
the damage to or destruction of the premises or the Building was caused by the
negligence or willful misconduct of, or a breach of this Lease by, Tenant, its
agents, contractors, or invitees, Tenant shall not have the right to cancel this
Lease and all repair or restoration obligations, less any amounts received under
applicable insurance policies, shall be paid by Tenant at its sole cost and
expense.  It shall be a condition to any cancellation of this Lease by Tenant
under this Paragraph 15.10 that Tenant fully pay any outstanding amounts due
under the Tenant Improvement Loan.  

    16. CONDEMNATION.

         16.1 PARTIAL TAKING. Subject to Paragraph 16.5, if part of the 
premises is taken for any public or quasi-public use, under any statute or right
of eminent domain (collectively a "taking"), and a part of the premises remains 
which is reasonably suitable for Tenant's continued occupancy for the uses 
permitted by this Lease, and a portion of the parking area within the Project 
remains which is reasonably sufficient for Tenant's needs, this Lease shall, as 
to the part so taken, terminate as of the date the condemnor or purchaser takes 
possession of the property being taken, and the monthly Base Rent payable 
hereunder shall be reduced in the same proportion that the floor area of the 
portion of the premises so taken bears to the total floor area of the premises 
immediately prior to such taking.  Landlord shall, at its own cost and expense, 
make all necessary repairs or alterations to the premises in order to make the 
portion of the premises not taken a complete architectural unit.  Each party 
hereto waives the provisions of California Code of Civil Procedure Section 
1265.130 allowing either party to petition the superior court to terminate this 
Lease in the event of a partial taking of the premises.

         16.2 TOTAL TAKING. Subject to Paragraph 16.5, if all of the premises 
are taken, or such part thereof is taken so that there does not remain a 
portion of the premises suitable for Tenant's continued occupancy for the 
uses permitted hereunder, or a portion of the parking area in the Project as 
of the Commencement Date is taken leaving insufficient parking to fulfill 
Tenant's reasonable needs, such taking shall be treated as a total taking and 
this Lease shall terminate upon the date possession shall be taken by the 
condemning authority.

         16.3 DISTRIBUTION OF AWARD.  All compensation awarded upon a taking 
governed by Paragraph 16.1 or Paragraph 16.2 shall belong to and be paid to 
Landlord, except that Tenant shall receive from the award a sum attributable to 
Tenant's improvements or alterations made to the premises by Tenant at Tenant's 
expense with Landlord's consent in accordance with this Lease.

         16.4 SALE UNDER THREAT OF CONDEMNATION.  A sale by Landlord to any 
authority having the power of eminent domain, either under threat of 
condemnation or while condemnation 

                                       27

<PAGE>


proceedings are pending, shall be deemed a taking under the power of eminent 
domain for purposes of this Paragraph 16.

         16.5 TEMPORARY TAKING. If all or any part of the premises is occupied,
taken, or appropriated by military or other public or quasi-public use or other 
governmental authority for less than one hundred eighty (180) consecutive days, 
it shall not constitute a taking of the premises which would be governed by 
Paragraph 16.1 or Paragraph 16.2.  In such event, during such a "temporary 
taking," all of the provisions of this Lease shall remain in force and effect, 
except that the monthly Base Rent payable during such temporary taking shall be 
reduced in the same proportion that the floor area of the portion of the 
premises so occupied, taken, or appropriated bears to the total floor area of 
the premises prior to such temporary taking.  Any award that may be paid in 
connection with such a temporary taking shall be paid to Landlord.  In the 
event a taking which appears, at its commencement, to be only a temporary 
taking nevertheless continues for one hundred eighty (180) consecutive days 
or more, a partial or total taking, as the case may be, shall be deemed to have 
occurred on the one hundred eightieth (180th) consecutive day of such taking, 
and shall be governed by the provisions of either Paragraph 16.1 or Paragraph 
16.2 as the case may be. 

    17. ASSIGNMENT AND SUBLETTING.  Subject to Paragraph 17.4 below, Tenant 
shall not assign this Lease, or any interest therein, voluntarily or 
involuntarily, and shall not sublet the premises or any part thereof, or any 
right or privilege appurtenant thereto, or suffer any other person (the agents 
and servants of Tenant excepted) to occupy or use the premises, or any portion 
hereof, without the prior written consent of Landlord in each instance pursuant
to the terms and conditions set forth below, which consent shall not 
unreasonably be withheld. 

         17.1 DOCUMENTATION. Prior to any assignment or sublease which Tenant 
desires to make, Tenant shall provide to Landlord the name and address of the 
proposed assignee or sublessee, a statement of the proposed use of the premises 
by the assignee or sublessee (including an indication of the extent to and 
manner in which Hazardous Materials [as defined in Paragraph 6.3(a)] will be 
utilized), and true and complete copies of all documents relating to Tenant's 
prospective agreement to assign or sublease, and shall specify all consideration
to be received by Tenant for such assignment or sublease in the form of lump sum
payments, installments of rent, or otherwise.  For purposes of this Paragraph 
17, the term "consideration" shall include, without limitation, all monies or 
other consideration of any kind, if such sums are related to Tenant's interest 
in this Lease or in the premises, including but not limited to, bonus money, and
payments (in excess of book value thereof) for Tenant's assets, fixtures,
inventory, accounts, good will, equipment, furniture, general intangibles, and
any capital stock or other equity ownership of Tenant.  Within fifteen (15)
business days after the receipt of such written notice, Landlord shall either
consent in writing to such proposed assignment or sublease subject to the terms
and conditions hereinafter set forth, or notify Tenant in writing that Landlord
refuses such consent, specifying reasonable grounds for such refusal. 
Landlord's failure to respond within such time period shall be deemed approval
of Tenant's request.  

         17.2 TERMS AND CONDITIONS.  As a condition to Landlord's granting its 
consent to any assignment or sublease, (a) Landlord may require that Tenant pay
to Landlord, as and when received by Tenant, one-half of the amount of any 
excess of such consideration to be received by Tenant in connection with said 
assignment or subletting over and above the rental amount fixed by this Lease 
and payable by Tenant to Landlord (prorated to reflect the rent allocable to the
portion of the premises subject to such assignment or sublease); provided that 
Tenant shall first be entitled to retain an amount of such excess consideration
equal to Tenant's unamortized costs of constructing that portion of the Tenant 
Improvements which shall be included in the portion of the premises subject to 
such assignment or sublease and Tenant's  

                                       28

<PAGE>


reasonable direct costs of assigning or subletting, including real estate 
brokerage commissions, if any, but not  including carrying costs due to vacancy
or otherwise, and (b) Tenant and the proposed assignee or sublessee must 
demonstrate to Landlord's reasonable satisfaction that the assignee or sublessee
is financially responsible and proposes to use the premises for substantially 
the same use or a use which is otherwise satisfactory to Landlord, and that the 
proposed use does not pose an unreasonable risk (as determined by Landlord in 
its reasonable discretion) of contamination of the Project with Hazardous 
Materials and is not otherwise injurious to the premises. 
Each assignment or sublease agreement to which Landlord has consented shall be
an instrument in writing in form satisfactory to Landlord, and shall be executed
by both Tenant and the assignee or sublessee, as the case may be.  Each such
assignment or sublease agreement shall recite that it is and shall be subject
and subordinate to the provisions of this Lease, that the assignee or sublessee
accepts such assignment or sublease and agrees to perform all of the obligations
of Tenant hereunder, and that the termination of this Lease shall, at Landlord's
sole election, constitute a termination of every such assignment or sublease. 
In the event Landlord shall consent to an assignment or sublease, Tenant shall
nonetheless remain primarily liable for all obligations and liabilities of
Tenant under this Lease, including but not limited to the payment of rent. 
Tenant agrees to reimburse Landlord upon demand for reasonable attorneys' fees
incurred by Landlord in connection with the negotiation, review, and
documentation of any such requested assignment or subleasing.  Tenant hereby
stipulates that the foregoing terms and conditions are reasonable.

         17.3 PARTNERSHIP.  If Tenant is a partnership, a transfer, voluntary 
or involuntary, of all or any part of an interest in the partnership, or the 
dissolution of the partnership, shall be deemed an assignment requiring 
Landlord's prior written consent.

         17.4 PERMITTED TRANSFERS. Tenant shall have the right, without 
Landlord's prior consent, to sublease or assign its interest under this 
Lease to any entity resulting from a merger, consolidation or corporate 
reorganization involving Tenant, or to any entity which controls, is controlled 
by or is under common control with Tenant or which purchases substantially all 
of the assets of Tenant, on the condition such subtenant or assignee shall have
a net worth, computed in accordance with generally accepted accounting 
principles, at least equal to the net worth of Tenant at the time of execution 
of this Lease.  Tenant shall provide Landlord with such subtenant or assignee's 
financial statements prior to such action to verify compliance with this 
condition.

         17.5 LANDLORD'S REMEDIES. Any assignment or sublease without Landlord's
prior written consent, except as permitted by Paragraph 17.4 above, shall at 
Landlord's election be void, and shall constitute a default.  The consent by 
Landlord to any assignment or sublease shall not constitute a waiver of the 
provisions of this Paragraph 17, including the requirement of Landlord's 
prior written consent, with respect to any subsequent assignment or sublease.
If Tenant shall purport to assign this Lease, or sublease all or any portion of 
the premises, or permit any person or persons other than Tenant to occupy the 
premises, without Landlord's prior written consent, except as permitted by 
Paragraph 17.4 above, Landlord may collect rent from the person or persons then 
or thereafter occupying the premises and apply the net amount collected to the 
rent reserved herein, but no such collection shall be deemed a waiver of 
Landlord's rights and remedies under this Paragraph 17, or the acceptance of any
such purported assignee, sublessee or occupant, or a release of Tenant from the 
further performance by Tenant of covenants on the part of Tenant herein 
contained.

         17.6 ENCUMBRANCES, LICENSES AND CONCESSION AGREEMENTS.  Tenant may 
encumber its interest under this Lease or any rights of Tenant hereunder, or 
enter into any license or concession agreement respecting all or any portion 
of the premises, without Landlord's prior written consent.

                                       29

<PAGE>

    18. DEFAULT BY TENANT.

         18.1 EVENT OF DEFAULT. The occurrence of any one or more of the 
following events (an "Event of Default") shall constitute a default and breach 
of this Lease by Tenant:

              (a) The failure by Tenant to make any payment of rent or any 
other payment requited to be made by Tenant hereunder, as and when due, and 
such failure shall not have been cured within three (3) days after written 
notice thereof from Landlord.  Any such notice shall constitute the notice 
required under Section 1161 of the California Code of Civil Procedure
(and/or any related or successor statutes regarding unlawful detainer actions),
provided such notice is given in accordance with the requirements of such
statute;

              (b) Tenant's failure to perform any other term, covenant or 
condition contained in this Lease and such failure shall have continued 
for thirty (30) days after written notice of such failure is given to 
Tenant; provided that, where such failure cannot reasonably be cured
within said thirty (30) day period, Tenant shall not be in default if Tenant
commences such cure within said thirty (30) day period and thereafter diligently
continues to pursue all reasonable efforts to complete said cure until
completion thereof;

              (c)  Tenant's assignment of its assets for the benefit of its
creditors;

              (d)  The sequestration of, attachment of, or execution on, any
substantial part of the property of Tenant or on any property essential to the
conduct of Tenant's business on the premises, and Tenant shall have failed to
obtain a return or release on such property within thirty (30) days thereafter,
or prior to sale pursuant to such sequestration, attachment or execution,
whichever is earlier;

              (e)  An entry of any of the following orders by a court having
jurisdiction, and such order shall have continued for a period of thirty (30)
days:  (1) an order for relief in any proceeding under Title 11 of the United
States Code, or an order adjudicating Tenant to be bankrupt or insolvent; (2) an
order appointing a receiver, trustee or assignee of Tenant's property in
bankruptcy or any other proceeding; or (3) an order directing the winding up or
liquidation of Tenant; or

              (f)  The filing of a petition to commence against Tenant an
involuntary proceeding under Title 11 of the United States Code, and Tenant
shall fail to cause such petition to be dismissed within thirty (30) days
thereafter.

         18.2 REMEDIES.  Upon any Event of Default, Landlord shall have the 
following remedies, in addition to all other rights and remedies provided by 
law or equity:

              (a) Landlord, as described in California Civil Code Section 
1951.4, shall be entitled to keep this Lease in full force and effect 
for so long as Landlord does not terminate Tenant's right
to possession (whether or not Tenant shall have abandoned the premises) and
Landlord may enforce all of its rights and remedies under this Lease, including
the right to recover rent and other sums as they become due under this Lease,
plus interest at the lesser of fifteen percent (15%) per annum or the highest
rate then allowed by law, from the due date of each installment of rent or other
sum until paid; or

              (b) Landlord may terminate the Tenant's right to possession 
by giving Tenant written notice of termination.  On the giving of the notice,
this Lease and all of Tenant's

                                       30



<PAGE>

rights in the premises shall terminate.  Any termination under this paragraph 
shall not release Tenant from the payment of any sum then due Landlord or 
from any claim for damages or rent previously accrued or then accruing 
against Tenant.

    In the event this Lease is terminated pursuant to this Paragraph 
18.2(b), Landlord may recover from Tenant:

                   (1)   the worth at the time of award of the unpaid rent 
which had been earned at the time of termination; plus

                   (2)   the worth at the time of award of the amount by 
which the unpaid rent which would have been earned after termination until 
the time of award exceeds the amount of such rental loss for the same period 
that Tenant proves could have been reasonably avoided; plus

                   (3)   the worth at the time of award of the amount by 
which the unpaid rent for the balance of the term after the time of award 
exceeds the amount of such rental loss for the same period that Tenant proves 
could be reasonably avoided; plus

                   (4)   any other amount necessary to compensate Landlord 
for all the detriment proximately caused by Tenant's failure to perform 
Tenant's obligations under this Lease, or which in the ordinary course of 
things would be likely to result therefrom, including without limitation, the 
following:  (i) expenses for cleaning, repairing or restoring the premises; 
(ii) real estate leasing commissions, advertising costs and other expenses of 
reletting the premises; (iii) costs incurred as owner of the premises 
including without limitation taxes, insurance premiums, utilities and 
building security; (iv) expenses in retaking possession of the premises; (v) 
reasonable attorneys' fees and court costs; and (vi) any unamortized lease 
commission paid in connection with this Lease.

    The "worth at the time of award" of the amounts referred to in 
subparagraphs (1) and (2) of this Paragraph 18.2(b) shall be computed by 
allowing interest at the lower of fifteen percent (15%) per annum, or the 
maximum rate then permitted by law.  The "worth at the time of award" of the 
amount referred to in subparagraph (3) of this paragraph shall be computed by 
discounting such amount at the discount rate of the Federal Reserve Board of 
San Francisco at the time of award plus one percent (1%).  The term "time of 
award" as used in subparagraphs (1), (2), and (3) shall mean the date of 
entry of a judgment or award against Tenant in an action or proceeding 
arising out of Tenant's breach of this Lease.  The term "rent" as used in 
this Paragraph shall include all sums required to be paid by Tenant to 
Landlord pursuant to the terms of this Lease.

              (c)  This Lease may be terminated by a judgment specifically 
providing for termination, or by Landlord's delivery to Tenant of written 
notice specifically terminating this Lease.  In no event shall any one or 
more of the following actions by Landlord, in the absence of a written 
election by Landlord to terminate this Lease, constitute a termination of 
this Lease or a waiver of Landlord's right to recover damages under this 
Paragraph 18:

                   (1)   appointment of a receiver in order to protect 
Landlord's interest hereunder;

                   (2)   consent to any subletting of the premises or 
assignment of this Lease by Tenant, whether pursuant to provisions hereof 
concerning subletting and assignment or otherwise; or

                                       31

<PAGE>


                   (3)   any other action by Landlord or Landlord's agents 
intended to mitigate the adverse effects of any breach of this Lease by 
Tenant, including without limitation any action taken to maintain and 
preserve the premises, or any action taken to relet the premises or any 
portion thereof for the account of Tenant and in the name of Tenant.

         18.3  NO RELIEF FROM FORFEITURE AFTER DEFAULT.  Tenant waives all 
rights of redemption or relief from forfeiture under California Code of Civil 
Procedure Sections 1174 and 1179, and under any other present or future law, 
in the event Tenant is evicted or Landlord otherwise lawfully takes 
possession of the premises by reason of any event of Default.

         18.4  LANDLORD'S RIGHT TO PERFORM TENANT'S OBLIGATIONS.  If Tenant 
at any time shall fail to make any payment or perform any other act required 
to be made or performed by Tenant under this Lease, then Landlord may, but 
shall not be obligated to, make such payment or perform such other act to the 
extent Landlord may deem desirable, and may, in connection therewith, pay any 
and all expenses incidental thereto and employ counsel.  No such action by 
Landlord shall be deemed a waiver by Landlord of any rights or remedies 
Landlord may have as a result of such failure by Tenant, or a release of 
Tenant from performance of such obligation.  All sums so paid by Landlord, 
including without limitation all penalties, interest and costs in connection 
therewith, shall be due and payable by Tenant to Landlord on the day 
immediately following any such payment by Landlord.  Landlord shall have the 
same rights and remedies for the nonpayment of any such sums as Landlord may 
be entitled to in the case of default by Tenant in the payment of rent.

         18.5  INTEREST ON PAST DUE OBLIGATIONS.  Any amount due to Landlord 
hereunder not paid when due shall bear interest at the lower of fifteen 
percent (15%) per annum, or the highest rate then allowed by law, from the 
date due until paid in full.  Payment of such interest shall not excuse or 
cure any default by Tenant under this Lease.

         18.6  ADDITIONAL RENT. All sums payable by Tenant to Landlord or to 
third parties under this Lease in addition to such sums payable pursuant to 
Paragraph 3 hereof shall be payable as additional sums of rent.  For purposes 
of any unlawful detainer action by Landlord against Tenant pursuant to 
California Code of Civil Procedure Sections 1161-1174, or any similar or 
successor statutes, Landlord shall be entitled to recover as rent not only 
such sums specified in Paragraph 3 as may then be overdue, but also all such 
additional sums of rent as may then be overdue.

         18.7  REMEDIES NOT EXCLUSIVE.  No remedy or election hereunder shall 
be deemed exclusive but shall, wherever possible, be cumulative with all 
other remedies herein provided or permitted at law or in equity.

    19.  DEFAULT BY LANDLORD.

         19.1  CURE PERIOD. Landlord shall not be deemed to be in default in 
the performance of any obligation required to be performed by it hereunder 
unless and until it has failed to perform such obligation within the period 
of time specifically provided herein, or if no period of time has been 
provided, then within thirty (30) days after receipt of written notice by 
Tenant to Landlord specifying wherein Landlord has failed to perform such 
obligation; provided, however, that if the nature of Landlord's obligation is 
such that more than thirty (30) days are reasonably required for its 
performance, then Landlord shall not be deemed to be in default if it shall 
commence such performance within such thirty (30) day period and thereafter 
diligently prosecute the same to completion.

                                      32

<PAGE>

         19.2  MORTGAGEE PROTECTION.  In the event of any default on the part 
of Landlord, Tenant will give notice by registered or certified mail to any 
beneficiary of a  deed of trust or mortgagee of a mortgage encumbering the 
premises whose address shall have been furnished to Tenant, and before Tenant 
shall have any right to terminate this Lease Tenant shall grant such 
beneficiary or mortgagee a reasonable period within which to cure the 
default, including a reasonable period to obtain possession of the premises 
by power of sale or judicial foreclosure, if such action is necessary to 
effect a cure.

    20.   ADVERTISEMENTS AND SIGNS. Tenant, at its cost, may place or permit 
to be placed on the exterior of the Building any reasonable signage desired 
by Tenant or its subtenants, provided such signs comply with all applicable 
laws, regulations and ordinances.  Upon termination of this Lease, Tenant 
shall remove any sign which it has placed in the Project or on the premises 
or the Building, and shall repair any damage caused by the installation or 
removal of such sign.

    21.   ENTRY BY LANDLORD.  Landlord and its agents shall be entitled to 
enter into and upon the premises at all reasonable times, upon reasonable 
notice (except in the case of an emergency, in which event no notice shall be 
required), for the following purposes:

              (a)    to inspect or make repairs, alterations or additions to 
all or any portion of the premises which Landlord may deem appropriate (i) to 
comply with any laws, ordinances, rules, regulations, or policies of any 
governmental authority or Landlord's insurance carrier(s), or (ii) to prevent 
waste or deterioration of the Project, or (iii) to promote the general 
welfare and safety of occupants of the Project, or (iv) to enhance the value 
of the Project, or (v) to perform construction work elsewhere in the Building 
adjacent to, above, or below the premises, including the erection and 
maintenance of such scaffolding, canopies, fences and props as may be 
required, provided that Landlord shall use due diligence not to unreasonably 
interfere with Tenant's use of the premises in connection with the above; or

              (b)    to post notices of non-responsibility for alterations, 
additions, or repairs; or

              (c)    to place upon the premises any ordinary "for sale" signs 
and to show the premises to prospective purchasers or lenders; and, during 
the ninety (90) day period prior to the expiration of this Lease, or upon any 
Event of Default, to place upon the premises any usual or ordinary "for 
lease" signs and exhibit the premises to prospective tenants at reasonable 
hours.

    Landlord's rights of entry as set forth in this Paragraph 21 shall be 
subject to the reasonable security regulations of Tenant, and to the 
requirement that Landlord shall use reasonable efforts to minimize 
interference with Tenant's business activities on the premises.  The 
preceding sentence shall not require the use of overtime labor or the conduct 
of any work or other activities of Landlord during Tenant's non-business 
hours.

    22.   SUBORDINATION, ATTORNMENT AND NON-DISTURBANCE.

          22.1  SUBORDINATION. Tenant agrees that this Lease may, at the 
option of Landlord, be subject and subordinate to any mortgage, deed of 
trust, or other  instrument of security now of record or which is recorded 
after the date of this Lease affecting the Project or any portion thereof, 
including the premises, and such subordination is hereby made effective 
without any further act of Tenant; provided that, no such subordination shall 
be effective unless

                                      33

<PAGE>

Landlord first obtains from a lender a written non-disturbance agreement 
reasonably acceptable to Tenant that provides in essence that as long as 
Tenant performs its obligations under this Lease, no foreclosure of, deed 
given in lieu of foreclosure of, or sale under, the encumbrance, and no steps 
or procedures taken under the  encumbrance, shall affect Tenant's rights 
under this Lease.  Tenant shall execute and return to Landlord the written 
agreement and any other documents required by the lender to accomplish the 
purposes of this paragraph, within fifteen (15) days after delivery thereof 
to Tenant, and the failure of Tenant to execute and return any such 
instruments shall constitute a default hereunder.

          22.2  ATTORNMENT.  Tenant shall attorn to any third party purchasing 
or otherwise acquiring the premises at any sale or other proceeding, or 
pursuant to the exercise of any rights, powers or remedies under any 
mortgages or deeds of trust or ground leases now or hereafter encumbering all 
or any part of the premises, as if such third party had been named as 
Landlord under this Lease.  Tenant shall execute a new lease with such new 
Landlord on the same terms of this Lease if so required by such new Landlord.

          22.3  NON-DISTURBANCE.  Landlord shall use due diligence and 
reasonable best efforts to obtain from any lender holding a security interest 
in the Project as of the date of this Lease a non-disturbance agreement for 
the benefit of Tenant on terms reasonably acceptable to Tenant.  

    23.   ESTOPPEL CERTIFICATES AND FINANCIAL STATEMENTS.  Tenant shall within 
fifteen (15) days following request by Landlord:  (a) execute and deliver to 
Landlord any documents, including estoppel certificates, in the form 
presented to Tenant by Landlord (1) certifying that this Lease has not been 
modified and is in full force and effect or, if modified, stating the nature 
of such modification and certifying that this Lease, as so modified, is in 
full force and effect, (2) stating the date to which the rent and other 
charges are paid in advance, if at all, (3) acknowledging that there are not, 
to Tenant's knowledge, any uncured defaults on the part of Landlord 
hereunder, or if there are uncured defaults on the part of Landlord, stating 
the nature of such uncured defaults, and (4) evidencing the status of this 
Lease as may be required either by a lender making a loan to Landlord to be 
secured by a deed of trust or mortgage encumbering the premises or a 
purchaser of the premises from Landlord; and (b) deliver to Landlord the 
current financial statements of Tenant with an opinion of a certified public 
accountant, if available at no additional cost to Tenant, including a balance 
sheet and profit and loss statement for the then current fiscal year, and the 
two (2) immediately prior fiscal years (if available) at no additional cost 
to Tenant, all prepared in accordance with generally accepted accounting 
principles consistently applied.  Tenant's failure to deliver any such 
documents, including an estoppel certificate, or any such financial 
statements within fifteen (15) days following such request shall be an Event 
of Default under this Lease.

    24.   NOTICES.  Any notice, approval, request, demand, or consent 
(collectively "notice") required or desired to be given under this Lease 
shall be in writing and shall be personally delivered or delivered by 
commercial courier (with signed receipt) or United States mail, registered or 
certified, postage prepaid, and addressed to the party to be notified at the 
last address given by that party to the other party under the provisions of 
this paragraph.  At the date of execution of this Lease, the addresses of 
Landlord and Tenant are as set forth above in the preamble to this Lease.  
Either party may change its address by notice to the other party.  Any notice 
delivered by United States mail pursuant to this paragraph shall be deemed to 
have been delivered three (3) days after the posted date of mailing.

    25.   WAIVER.  The waiver by either party of any breach of any term, 
covenant, or condition herein contained shall not be deemed to be a waiver of 
such term, covenant or

                                       34

<PAGE>

condition or any subsequent breach of the same or any other term, covenant or 
condition herein contained.  The subsequent acceptance of rent hereunder by 
Landlord shall not be deemed to be a waiver of any preceding breach by Tenant 
of any term, covenant or condition of this Lease, other than the failure of 
Tenant to pay the particular rental so accepted, regardless of Landlord's 
knowledge of such preceding breach at the time of acceptance of such rent.  
No term, covenant or condition shall be deemed to have been waived by either 
party unless such waiver is in writing and signed by the party making such 
waiver.

    26.   NO ACCORD AND SATISFACTION.  No payment by Tenant, or receipt by 
Landlord, of an amount which is less than the full amount of rent and all 
other sums payable by Tenant hereunder at such time shall be deemed to be 
other than on account of (a) the earliest of such other sums due and payable, 
and thereafter (b) to the earliest rent due and payable hereunder. No 
endorsement or statement on any check or any letter accompanying any payment 
of rent or such other sums shall be deemed an accord and satisfaction, and 
Landlord may accept any such check or payment without prejudice to Landlord's 
right to receive payment of the balance of such rent and/or the other sums, 
or Landlord's right to pursue any remedies to which Landlord may be entitled 
to recover such balance.

    27.   ATTORNEY'S FEES.  If any action or proceeding at law or in equity, 
or an arbitration proceeding (collectively an "action"), shall be brought to 
recover any rent under this Lease, or for or on account of any breach of or 
to enforce or interpret any of the terms, covenants, or conditions of this 
Lease, or for the recovery of possession of the premises, the prevailing 
party shall be entitled to recover from the other party as a part of such 
action, or in a separate action brought for that purpose, its reasonable 
attorney's fees and costs and expenses (including expert witness fees) 
incurred in connection with the prosecution or defense of such action.  
"Prevailing party" within the meaning of this paragraph shall include, 
without limitation, a party who brings an action against the other after the 
other is in breach or default, if such action is dismissed upon the other's 
payment of the sums allegedly due or upon the other's performance of the 
covenants allegedly breached, or if the party commencing such action or 
proceeding obtains substantially the relief sought by it in such action, 
whether or not such action proceeds to a final judgment or determination.

    28.   SURRENDER.  Tenant shall, upon expiration or sooner termination of 
this Lease, surrender the premises to Landlord in the same condition as 
existed upon completion of the Tenant Improvements (reasonable wear and tear 
and damage due to causes beyond the reasonable control of Tenant excepted) 
with all HVAC equipment in operating order and in good repair.  Tenant shall 
at such time also surrender to Landlord such alterations (as defined in 
Paragraph 9) as Landlord does not require Tenant to remove (or which Tenant 
has the right to remove) in accordance with Paragraph 9.6 above.  Tenant, on 
or before the expiration or sooner termination of this Lease, shall remove 
all of its personal property and trade fixtures from the premises, and all 
property not so removed shall be deemed abandoned by Tenant.  Tenant shall be 
liable to Landlord for costs of removal of any such abandoned trade fixtures 
or equipment of Tenant, or of any alterations Tenant fails to remove if so 
required by Landlord.  If the premises are not so surrendered at the 
expiration or sooner termination of this Lease, Tenant shall indemnify 
Landlord against loss or liability resulting from delay by Tenant in so 
surrendering the premises, including without limitation, any claims made by 
any succeeding tenant founded on such delay, losses to Landlord due to lost 
opportunities to lease to succeeding tenants, and reasonable attorneys' fees 
and costs.  All keys to the premises or any part thereof shall be surrendered 
to Landlord upon expiration or sooner termination of the Lease term.

    29.   HOLDING OVER.  This Lease shall terminate without further notice at 
the expiration of the Lease term.  Any holding over by Tenant after 
expiration shall not constitute a renewal or 

                                      35

<PAGE>

extension of the Lease term or give Tenant any rights in or to the premises 
unless otherwise expressly provided in this Lease.  Any holding over after 
expiration of the Lease term with the express written consent of Landlord 
shall be construed to be a tenancy from month to month, at one hundred 
twenty-five percent (125%) of the monthly Base Rent for the last month of the 
Lease term, and shall otherwise be on the terms and conditions herein 
specified insofar as applicable, unless otherwise mutually agreed in writing 
by the parties.

    30.   TRANSFER OF PREMISES BY LANDLORD.  The term "Landlord" as used in 
this Lease, so far as the covenants or obligations on the part of Landlord 
are concerned, shall be limited to mean and include only the owner at the 
time in question of the fee title to the premises.  In the event of any 
transfer of such fee title, the Landlord herein named (and in case of any 
subsequent transfer or conveyance, the then grantor) shall after the date of 
such transfer or conveyance be automatically freed and relieved of all 
liability with respect to performance of any covenants or obligations on the 
part of Landlord contained in this Lease thereafter to be performed; 
provided, that any funds in the hands of Landlord or the then grantor at the 
time of such transfer in which Tenant has an interest, shall be turned over 
to the grantee.  The covenants and obligations contained in this Lease on the 
part of Landlord shall, subject to the foregoing, be binding upon each 
Landlord hereunder only during this or its respective period of ownership.

    31.   RULES AND REGULATIONS OF BUILDING.

          31.1     The sash doors, sashes, windows, glass doors, lights, and 
skylights that reflect or admit light into the halls or other places of the 
Building shall not be covered or obstructed.  The toilets and urinals shall 
not be used for any purpose other than those for which they were constructed, 
and no rubbish, newspapers or other substances of any kind shall be thrown 
into them.  The expense of any breakage, stoppage or damage resulting from a 
violation of this rule shall be borne by Tenant.

          31.2     Landlord acknowledges that Tenant intends to install a new 
security system for the premises in connection with Tenant's construction of 
the Tenant Improvements, and that Landlord shall have the right to reasonably 
approve such new system pursuant to the provisions of Paragraph 34 below.  
Following the installation of such new security system, no additional lock or 
locks shall be placed by Tenant on any exterior door in the Building unless 
written consent of Landlord shall have first been obtained.  All keys shall 
be surrendered to Landlord upon termination of the tenancy.

          31.3     Tenant and its guests and employees shall not bring into 
or keep within the Building any animal (with the exception of guide dogs for 
the blind) or motorcycle or other motor vehicle.  Such prohibition shall not 
apply to Tenant's use of loading docks and similar improvements which 
customarily involve motor vehicles.

          31.4     Any window covering installed by Tenant must be of such 
uniform shape, color, material and make as may first be approved by Landlord.

          31.5     Except for authorized maintenance personnel, and persons 
engaged in the construction of the Tenant Improvements, neither Tenant nor 
its employees or invitees shall go upon the roof.

          31.6     Landlord shall have the right to prohibit any advertising 
by Tenant which, in Landlord's reasonable opinion, tends to impair the 
reputation of the Building or the Project, and upon written notice from 
Landlord, Tenant shall refrain from or discontinue such advertising.

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<PAGE>

    32.   GENERAL PROVISIONS.

          32.1  ENTIRE AGREEMENT. This instrument including the Exhibits 
attached hereto contains all of the agreements and conditions made between 
the parties hereto and may not be modified orally or in any manner other than 
by an agreement in writing signed by all of the parties hereto or their 
respective successors in interest.  Any executed copy of this Lease shall be 
deemed an original for all purposes.

          32.2  TIME.  Time is of the essence with respect to the performance 
of each and every provision of this Lease in which time of performance is a 
factor.  All references to days contained in this Lease shall be deemed to 
mean calendar days, unless otherwise specifically stated.

          32.3  CAPTIONS.  The captions and headings of the numbered 
paragraphs of this Lease are inserted solely for the convenience of the 
parties hereto, and are not a part of this Lease and shall have no effect 
upon the construction or interpretation of any part hereof.

          32.4  CALIFORNIA LAW. This Lease shall be construed and interpreted 
in accordance with the laws of the State of California.  The language in all 
parts of this Lease shall in all cases be construed as a whole according to 
its fair meaning and not strictly for or against either Landlord or Tenant, 
and without regard to which party prepared this Lease.

          32.5  GENDER; SINGULAR AND PLURAL.  When required by the context of 
this Lease, the neuter includes the masculine, the feminine, a partnership, a 
corporation, or a joint venture, and the singular shall include the plural.

          32.6  PARTIAL INVALIDITY. If any provision of this Lease is held by 
a court of competent jurisdiction to be invalid, void, or unenforceable, the 
remainder of the provisions hereof shall nonetheless continue in full force 
and effect and shall in no way be affected, impaired, or invalidated thereby.

          32.7  NO WARRANTIES.  Any agreements, warranties or representations 
not expressly contained herein shall not bind either Landlord or Tenant, and 
Landlord and Tenant expressly waive all claims for damages by reason of any 
statement,  representation, warranty, promise or agreement, if any, not 
expressly contained in this Lease.

          32.8  JOINT AND SEVERAL LIABILITY.  If Tenant is more than one 
person or entity, each such person or entity shall be jointly and severally 
liable for the obligations of Tenant hereunder.

          32.9  SUCCESSORS AND ASSIGNS.  The covenants and conditions herein 
contained, subject to the provisions as to assignment, shall inure to the 
benefit of and bind the heirs, executors, administrators, assigns, and any 
other person or entity succeeding lawfully, and pursuant to the provisions of 
this Lease, to the rights or obligations of the respective parties hereto.

          32.10 RULES AND REGULATIONS.  Landlord may from time to time 
promulgate reasonable rules and regulations in addition to those set forth in 
Paragraph 31 above for the use, safety, care and cleanliness of the premises, 
and the preservation of good order thereon.  Such rules and regulations shall 
be binding upon Tenant upon delivery of a copy thereof to Tenant,

                                      37

<PAGE>

and Tenant shall abide by all such rules and regulations, provided such rules 
do not unreasonably interfere with Tenant's use of the premises.  If there is 
a conflict between such rules and regulations and any of the provisions of 
this Lease, the provisions of this Lease shall prevail.

          32.11 AUTHORITY.  The individuals signing this Lease hereby 
represent and warrant that they have all necessary power and authority to 
execute and deliver this Lease on behalf of Landlord and Tenant, respectively.

          32.12 MEMORANDUM OF LEASE. Landlord and Tenant agree to  record a 
short form memorandum hereof to give notice of this Lease and the Option 
Agreement.

          32.13 MERGER.  The voluntary or other surrender of this Lease, or a 
mutual cancellation thereof, shall not work an automatic merger, but shall, 
at the sole option of Landlord, either terminate all or any existing 
subleases or subtenancies, or operate as an assignment to Landlord of any or 
all of such subleases or subtenancies.

          32.14 FORCE MAJEURE. Any prevention of or delay in the performance 
by a party hereto of its obligations under this Lease caused by inclement 
weather, labor disputes (including strikes and lockouts), inability to obtain 
materials or reasonable substitutes therefor, governmental restrictions, 
regulations, controls, action or inaction,  civil commotion, fire or other 
causes beyond the reasonable control of the party obligated to perform 
(except financial inability), shall excuse the performance by such party of 
its obligations hereunder (except the obligation of Tenant to pay rent and 
other sums hereunder) for a period of one day for each such day of delay.

          32.15 REAL ESTATE BROKERS.  Except for CB Commercial Real Estate 
Group, Inc., representing Tenant, and Cornish & Carey Commercial, 
representing Landlord, whose commissions or fees shall be paid by Landlord in 
accordance with the provisions of  separate commission agreements, each party 
represents to the other that it has not had any dealings with any real estate 
broker, finder, or other person entitled to any commission, with respect to 
this Lease, and each party shall indemnify and hold harmless the other party 
from all damages, expenses, and liabilities resulting from any claims that 
may be asserted against the indemnified party by any broker, finder, or other 
person entitled to any commission with whom the indemnifying party has or 
purportedly has dealt.

    33.   OPTION(S) TO EXTEND.

          33.1  OPTIONS.  Subject to the remaining provisions of this 
Paragraph 33, Tenant shall have three (3) option(s) (each an "Option") to 
extend the term of this Lease, with each Option respecting the time period 
(each an "Extended Term") set forth below:

         First Option                  Five (5) years
         Second Option            Five (5) years
         Third Option                  Five (5) years


Tenant shall exercise an Option, if at all, by giving Landlord written notice 
of Tenant's intention to do so at least one hundred eighty (180) days prior 
to the expiration of the original term hereof or the then current Extended 
Term, as the case may be.  Notwithstanding the foregoing, Tenant shall not 
have the right to exercise an Option if (a) Tenant has not exercised all 
prior available Options to extend the term of this Lease set forth above, or 
(b) Tenant is in material default under

                                      38
<PAGE>

this Lease at the time of the purported Option exercise.  Each Extended Term 
shall be upon all of the terms and conditions hereof, including, without 
limitation, the size of the premises in effect at the expiration of the 
initial term, except that the monthly Base Rent for such Extended Term shall 
be determined in accordance with Paragraph 33.2.  Upon commencement of each 
Extended Term, all references herein to the "term" or "Term" of this Lease 
shall be deemed to include such Extended Term.  

         33.2 EXTENDED TERM RENT.  Within thirty (30) days after Landlord's
receipt of Tenant's notice of exercise of an Option, Landlord shall deliver to
Tenant a proposal setting forth the monthly Base Rent for the upcoming Extended
Term.  Landlord's proposal shall be based upon the fair market rental for the
premises in the deemed condition described in the next paragraph below.  If
Tenant within ten (10) business days after receipt of such proposal agrees to
such proposal, the amount of monthly Base Rent set forth in such proposal shall
be binding on Landlord and Tenant.  Should Tenant object in writing to
Landlord's proposal within ten (10) business days after receipt thereof, or fail
to respond within such period (which failure shall be deemed an objection), then
during the ten (10) business day period following Tenant's objection to
Landlord's proposal, Landlord and Tenant shall negotiate in good faith for the
purpose of reaching an agreement regarding the amount of the monthly Base Rent
during the upcoming Extended Term.  In the event the parties fail to agree in a
written instrument signed by both parties upon the amount of the monthly Base
Rent for the upcoming Extended Term within such ten (10) business day period,
the monthly Base Rent for the upcoming Extended Term shall be determined by
appraisal in the manner hereafter set forth; provided, however, that in no event
shall the monthly Base Rent for the upcoming Extended Term be less than the
monthly Base Rent payable hereunder for the last full month of the term of this
Lease (including any then current Extended Term) immediately preceding
commencement of the upcoming Extended Term.  For purposes of the preceding
sentence, the amount of monthly Base Rent for the last month of the Lease term
shall not be reduced to reflect any abatement of rent which may then be in
effect.  

    In the event it becomes necessary under this Paragraph 33.2 to determine
the fair market monthly Base Rent of the premises by appraisal, Landlord and
Tenant each shall appoint an experienced real estate appraiser who shall be a
member of the American Institute of Real Estate Appraisers ("AIREA"), and such
appraisers shall each determine the fair market monthly Base Rent for the
premises in accordance with the provisions below.  Notwithstanding the actual
physical condition of the premises at such time, such appraisers shall be
instructed to value the premises as a research and development "shell" space in
good condition ready for installation of tenant improvements.  Landlord and
Tenant agree that such deemed condition shall include a completed weather tight
exterior, with all exterior glass and doors installed, and with all typical
office building operating systems (e.g., electrical, plumbing and HVAC)
installed to central supply locations in the premises, without any distribution
improvements for such operating systems.  Landlord and Tenant intend that such
valuation shall be similar to that for a research and development facility of
similar proportions, in the condition described above, located on the San
Francisco Peninsula.  Landlord and Tenant acknowledge that the purposes of
utilizing the deemed condition described above is to exclude from the
determination of the fair market monthly Base Rent for the premises the value of
specialized tenant improvements installed by Tenant at its cost, but to
compensate Landlord for the value of the premises as a completed shell in good
condition with the improvements described above.  The appraisers shall, within
twenty (20) business days after their appointment, complete their appraisals and
submit their appraisal reports to Landlord and Tenant.  If the fair market
monthly Base Rent of the premises established in the two (2) appraisals varies
by five percent (5%) or more of the higher rental, said appraisers, within ten
(10) days after submission of the last appraisal, shall appoint a third
appraiser who shall be a member of the AIREA.  Such third appraiser shall,
within twenty (20) business days

                                      39

<PAGE>


after his appointment, determine by appraisal the fair market monthly Base Rent
of the premises, taking into account the same factors referred to above, and
submit his appraisal report to Landlord and Tenant.  The fair market monthly
Base Rent determined by the third appraiser for the premises shall be
controlling, unless it is less than that set forth in the lower appraisal
previously obtained, in which case the rental set forth in said lower
appraisal shall be controlling, or unless it is greater than that set forth
in the higher appraisal previously obtained, in which case the rental set
forth in said higher appraisal shall be controlling.  If either Landlord or
Tenant fails to appoint an appraiser, or if an appraiser appointed by either of
them fails, after his appointment, to submit his appraisal within the required
period in accordance with the foregoing, the appraisal submitted by the
appraiser properly appointed and timely submitting his appraisal shall be
controlling.  If the two appraisers appointed by Landlord and Tenant are unable
to agree upon a third appraiser within the required period in accordance with
the foregoing, application shall be made within twenty (20) days thereafter by
either Landlord or Tenant to the AIREA, which shall appoint a member of said
institute willing to serve as appraiser.  The cost of all appraisals under this
subparagraph shall be borne equally by Landlord and Tenant.

    34.    PERFORMANCE OF LANDLORD'S WORK; CONSTRUCTION OF TENANT IMPROVEMENTS.

         34.1 DEFINITIONS.

              (a)  The term "Landlord's Work" shall mean those obligations that
Landlord is obligated to perform in the Building in accordance with Paragraph
34.2(f) below.  Landlord's Work shall include:  (i)  demolition of existing
interior improvements in the initial Phase I premises, (ii) removal and/or
abatement of any Hazardous Materials (including asbestos containing materials)
located in the interior of the premises or on the roof thereof, and (iii)
removal of all heating and air conditioning equipment on the roof of the
premises, excepting that equipment which is designated to remain in that certain
report entitled Inhale Belmont Survey prepared by Helwig Mechanical dated
August 27, 1996.

              (b)  The term "Tenant Improvements" shall mean those improvements
that Tenant is obligated to construct in the Building pursuant to plans and
specifications developed therefor in accordance with Paragraph 34.2(a).

              (c)  The term "Tenant Improvement Costs" shall mean all sums
(1) paid to contractors for labor and materials furnished in connection with
construction of the Tenant Improvements pursuant to Paragraph 34.2 below; (2)
all costs, expenses, payments, fees, and charges whatsoever paid or incurred by
Tenant to or at the direction of any city, county, or other governmental
authority or agency which are required to be paid by Tenant in order to obtain
all necessary governmental permits, licenses, inspections and approvals relating
to the construction of the Tenant Improvements and the use and occupancy of the
premises, including without limitation all in lieu fees and utility fees;
(3) engineering and architectural fees for services required in connection with
the design and construction of the Tenant Improvements; and (4) premiums, if
any, for course of construction insurance and for payment and completion bonds
relating only to construction of the Tenant Improvements. 

              (d)  The term "Tenant's Improvement Allowance" shall mean the
maximum amount Landlord is required to spend toward the payment of Tenant
Improvement Costs, which amount is Five Million Dollars ($5,000,000).  The
Tenant's Improvement Allowance shall be funded by Landlord from the proceeds of
the Tenant Improvement Loan.  

              (e)  The term "substantially complete" shall mean all
improvements required by the Approved Plans (as defined in Paragraph 34.2(a)
below) have been installed,


                                      40

<PAGE>



subject to any required repair and replacement items set forth on the
"punchlist" prepared by Landlord and approved by Tenant pursuant to
Paragraph 34.3 below.  

              (f)  The term "Landlord Owned Improvements" shall mean a portion
of the Tenant Improvements with a fair market value of Five Million Dollars
($5,000,000) at the time the Tenant Improvements are substantially complete,
which improvements shall be owned by Landlord for the purposes of this Lease,
subject to the provisions of Paragraph 34.2(g) below.  

         34.2 PROCEDURE AND TIME SCHEDULES..

              (a)  APPROVAL OF PLANS.  Within one hundred twenty (120) days
after execution of this Lease by both parties hereto, Tenant shall prepare and
deliver to Landlord for its approval preliminary plans and specifications for
the Tenant Improvements.  Landlord's approval shall not be unreasonably withheld
and Landlord shall grant or withhold such approval within ten (10) days
following Landlord's receipt of such preliminary plans and specifications. 
Landlord's failure to respond with such time period shall be deemed approval of
such preliminary plans and specifications.  The preliminary plans and
specifications shall be accompanied by a reasonably detailed written estimate
from Tenant's contractor(s) indicating the estimated cost of construction of the
Tenant Improvements based upon best available information.  Tenant acknowledges
and agrees that Tenant has advised Landlord that the anticipated cost of the
Tenant Improvements is approximately Fifteen Million Dollars ($15,000,000), and
that construction of Tenant Improvements in the Building of such scope is a
material consideration for Landlord's execution of this Lease.  Therefore,
Tenant agrees it shall be reasonable for Landlord to withhold its consent to
such plans and specifications if the scope of the Tenant Improvements is less
than that anticipated by the parties at the time of execution of this Lease,
provided, however, that Tenant shall have the right to construct the full scope
of Tenant Improvements in phases, the timing and scope of which shall be
determine by Tenant.  The estimated cost of the Tenant Improvements for the
purposes of this Paragraph 34.2(a) shall not include the cost of the equipment, 
fixtures and other personal property which Tenant intends to install in the
premises, but shall include those items which comprise the Tenant Improvement
Costs as set forth in Paragraph 34.1(c) above.  Within sixty (60) days after
Landlord's approval, Tenant shall prepare final plans, specifications and
working drawings for the Tenant Improvements that are consistent with and are
logical evolutions of the preliminary plans and specifications approved by
Landlord.  As soon as the final plans, specifications and working drawings are
completed, Tenant shall deliver the same to Landlord for its approval, which
shall not be unreasonably withheld and which shall be granted or withheld by
Landlord within ten (10) days of Landlord's receipt of the final plans,
specifications and working drawings.  Landlord's failure to respond within such
time period shall be deemed approval of such final plans, specifications and
working drawings.  In all events, the parties shall use their best efforts to
reach agreement so that such plans may be submitted for governmental approval as
soon as reasonably practicable.  Landlord and Tenant shall indicate their
approval thereof by initialing and dating the same and a copy of the final
Tenant Improvement plans shall be attached hereto as a supplement to Exhibit "A"
and shall become a part hereof.  Tenant shall submit such final plans,
specifications and working drawings to all appropriate governmental agencies for
approval.  Tenant will notify Landlord of any changes required by any
governmental agencies, and all such changes shall be deemed acceptable to
Landlord unless the exterior, structural portions or operating systems of the
Building are substantially affected by such changes, in which event such changes
shall be subject to Landlord's reasonable approval, which approval shall be
granted or withheld with ten (10) days of Landlord's receipt of such changes. 
Landlord's failure to respond within such period shall be deemed approval of
such changes.  The final plans, specifications and


                                       41

<PAGE>


working drawings as approved, and all change orders specifically permitted
pursuant to Paragraph 34.2(c) below, shall be referred to herein as the
"Approved Plans."

              (b)  CONTRACTORS.  The Tenant Improvements shall be constructed
by Tenant and its general contractor.  All parties shall use their best efforts
to complete the preparation and approval of the Approved Plans so that
construction contracts may be executed to insure completion prior to the Rent
Commencement Date.

              (c)  CHANGES TO APPROVED PLANS FOR TENANT IMPROVEMENTS. 
Following final approval by Landlord and Tenant of the Approved Plans, Tenant
shall have the right to modify the Approved Plans subject to the condition that
any modification applicable to the exterior, the structural components or the
mechanical, electrical, plumbing or utility systems of the Building (to the
extent such modifications to systems affect the use or condition of other
portions of the Building outside the initial premises) shall be subject to
Landlord's prior written approval, such approval not to be unreasonably withheld
or conditioned.  Landlord shall advise Tenant of its approval or disapproval of
such modifications within seven (7) days of receipt thereof.  Landlord's failure
to respond within such period shall be deemed approval of such modifications.

              (d)  COMMENCEMENT AND COMPLETION OF THE TENANT IMPROVEMENTS. As
soon as (1) the Approved Plans have been developed as provided above, and (2)
all necessary governmental approvals have been obtained, then Tenant shall
thereafter commence construction of such improvements and shall diligently
prosecute such construction to completion (subject to Tenant's right to complete
such improvements in phases as described in Paragraph 34.2 (a) above), using due
diligence so that the Tenant Improvements may be substantially completed by the
estimated Rent Commencement Date.  Such improvements shall be constructed by
Tenant substantially in accordance with the Approved Plans, and in compliance
with all applicable regulations, ordinances, building codes, and statutes of
lawful governmental authority.

              (e)  PAYMENT OF COST OF TENANT IMPROVEMENTS.  Landlord shall pay
a portion of the Tenant Improvement Costs up to an amount equal to Tenant's
Improvement Allowance.  Tenant shall pay the entire amount of the Tenant
Improvement Costs in excess of the Tenant's Improvement Allowance.  As indicated
above, the Tenant's Improvement Allowance shall be funded by the Tenant
Improvement Loan.  Landlord shall not be obligated to disburse to Tenant any
portion of the proceeds of the Tenant Improvement Loan until Landlord has
received and approved reasonably detailed supporting documentation evidencing
Tenant's expenditure of Five Million Dollars ($5,000,000) or more toward the
payment of the Tenant Improvement Costs.  Landlord's approval of such evidence
shall not be unreasonably withheld and shall be granted or withheld within ten
(10) days of Landlord's receipt of such documentation.  Landlord's failure to
respond within such period shall be deemed approval of such documentation. 
Landlord acknowledges and agrees that, due to Tenant's agreement to pay all
costs which arise in connection with the Tenant Improvement Loan, Landlord shall
not unreasonably withhold or condition its consent to any disbursement, escrow
or similar funding mechanisms requested by Tenant with respect to the Tenant's
Improvement Allowance, so long as Landlord is afforded the opportunity to review
reasonably detailed documentary evidence confirming that the proceeds of the
Tenant Improvement Loan shall be utilized to pay Tenant Improvement Costs and
for no other purpose.  Landlord and Tenant acknowledge and agree that such
disbursement procedures shall be determined by Tenant, subject to Landlord's
reasonable approval, based upon, among other factors, the timing of the
availability of the Tenant Improvement Loan proceeds and the requirements of the
lender under such loan.  Without modifying the foregoing, Landlord agrees that,
if the proceeds of the Tenant Improvement Loan are available during the period
of construction of the Tenant Improvements, Landlord shall,


                                    42


<PAGE>


unless otherwise agreed to by the parties in accordance with the above,
make progress payments within fifteen (15) business days of receipt of
invoices and reasonable supporting documentation from Tenant or Tenant's
contractor showing the amount then payable by Landlord with respect to the
Tenant Improvements. Notwithstanding any provisions of this Lease to the
contrary, Landlord's maximum required contribution toward the payment of
Tenant Improvement Costs shall be Five Million Dollars ($5,000,000), and
Landlord shall have no obligation to pay any amount over such maximum
contribution.  Landlord shall use due diligence and reasonable best
efforts to obtain the Tenant Improvement Loan in order to fund the Tenant's
Improvement Allowance as provided above.  If, despite the exercise of such due
diligence and reasonable best efforts, Landlord is unable to secure
the Tenant Improvement Loan by the date which is one (1) year from the Rent
Commencement Date, or if Tenant elects not to proceed with the Tenant
Improvement Loan in accordance with the provisions of Paragraph 3.1(b) above,
then Tenant shall pay all Tenant Improvement Costs, no Tenant Improvement Base
Rent shall be included in the Base Rent pursuant to the provisions of Paragraph
3.1(b) above and the Base Rent credit provisions of Paragraph 3.2(b) above shall
apply.

              (f)  LANDLORD'S WORK.  Landlord shall use due diligence to
complete Landlord's Work in accordance with all applicable laws, regulations and
ordinances on or before December 1, 1996.  Landlord shall perform Landlord's
Work at Landlord's sole cost.  In the event Landlord has not completed
Landlord's Work by January 1, 1997, Tenant shall have the right, upon delivery
of written notice to Landlord, to complete the Landlord's Work and to pay all
reasonable costs incurred by Tenant in connection with such completion.  In the
event Tenant exercises its right to complete Landlord's Work in accordance with
the preceding sentence, Tenant shall have the right to credit all reasonable
costs incurred by Tenant in connection therewith against Base Rent next due and
payable under this Lease.  Notwithstanding the date for Landlord's performance
of Landlord's Work set forth above, Landlord shall not be obligated to remove
Hazardous Materials from the Phase II, Phase III or Phase IV spaces until
Landlord receives Tenant's written exercise of Tenant's option to expand into
each such space.

              (g)  OWNERSHIP OF TENANT IMPROVEMENTS.  On the conditions that
Landlord obtains the Tenant Improvement Loan and pays the Tenant's Improvement
Allowance in accordance with the provisions of this Lease, Landlord shall be the
owner of that portion of the Tenant Improvements which is the Landlord Owned
Improvements.  Landlord shall be entitled to depreciate the Landlord Owned
Improvements during the period of Landlord's ownership thereof.  In the event
Tenant desires to prepay the Tenant Improvement Loan as set forth in Paragraph
3.1(b) above, or upon the full repayment of the Tenant Improvement Loan in
accordance with its terms, Landlord shall at such time sell the Landlord Owned
Improvements to Tenant for an amount equal to the balance of principal and
interest then outstanding under the Tenant Improvement Loan, plus all costs and
expenses, including prepayment premiums, which Landlord will incur in connection
with such prepayment (or in the case of full repayment, the purchase price shall
be equal to the final payment made by Tenant under the Tenant Improvement Loan).
Following such sale, Tenant shall be the sole owner of the Tenant Improvements
during the Term or any Extended Term of this Lease.

         34.3 DELIVERY OF POSSESSION.  When the Tenant Improvements are
substantially completed, Landlord and Tenant shall together walk through and
inspect the premises and Tenant Improvements so completed (which inspection
shall include the testing of any utility facilities, lighting, HVAC equipment,
and other service equipment affecting the premises) using their best efforts to
discover all incomplete or defective construction.  After such inspection has
been completed, a list of "punchlist" items applicable to the exterior,
structural aspects and the mechanical, electrical, plumbing and utility systems
of the Building shall be prepared by Landlord which the parties agree are to be
corrected by Tenant.  Tenant shall use due diligence to



                                    43


<PAGE>


complete and/or repair such "punchlist" items within thirty (30) days.
Landlord acknowledges that the purpose of such punchlist is to finalize
construction of exterior portions of the Tenant Improvements and other
components of the Tenant Improvements which affect the structure of the
Building or Landlord's use or the condition of the balance of the Building
outside of the initial premises, and that Landlord shall not be in control of,
or have the right to direct Tenant with respect to, completion of the Tenant
Improvements which are exclusively within or affect only the premises.  

    IN WITNESS WHEREOF, Landlord and Tenant have executed this Lease as of the
date first above specified.  Delivery of this Lease to Landlord, duly executed
by Tenant, constitutes an offer by Tenant to lease the premises as herein set
forth, and under no circumstances shall such delivery be deemed to create an
option or reservation to lease the premises for the benefit of Tenant.  This
Lease shall only become effective and binding upon execution of this Lease by
Landlord and delivery of a signed copy to Tenant.


                             LANDLORD:

                             TMT Associates, LLC, a California limited
                             liability company

Date: 10/2/96                By: /s/ Kiet Nguyen
      ------------------         -----------------------------
                                  Kiet Nguyen, Member

                             and

Date: 10/2/96                By: /s/ Thomas Peirona
      ------------------         -----------------------------
                                  Thomas Peirona, Member


                             TENANT:

                             Inhale Therapeutic Systems,
                             a California corporation

Date: 10/2/96                By: Robert B. Chess
      ------------------         -----------------------------

                             Its: President
                                  ----------------------------



                                    44

<PAGE>


                                 EXHIBIT C
                                           
                                           
                        HAZARDOUS MATERIAL REPORTS
                                           



1.  Phase I Environmental Assessment Report prepared by Phase One, Inc., dated
    July, 1993.

2.  Phase II Site Investigation Results prepared by Geomatrix Consultants,
    Inc., dated November, 1994.

3.  Final Phase II Site Investigation Report prepared by Geomatrix Consultants,
    Inc., dated November, 1995.  


                                    

                                    1




<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE BALANCE
SHEET AND INCOME STATEMENT ON PAGES 3 AND 4 AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1996
<PERIOD-END>                               SEP-30-1996
<CASH>                                           8,631
<SECURITIES>                                    22,409
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                33,143
<PP&E>                                           3,488
<DEPRECIATION>                                       0
<TOTAL-ASSETS>                                  36,833
<CURRENT-LIABILITIES>                            3,346
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                                0
                                          0
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<TOTAL-LIABILITY-AND-EQUITY>                    36,833
<SALES>                                              0
<TOTAL-REVENUES>                                 4,722
<CGS>                                                0
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<OTHER-EXPENSES>                                     0
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<INTEREST-EXPENSE>                                  47
<INCOME-PRETAX>                                (6,639)
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