APROGENEX INC
8-K, 1996-06-27
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, DC  20549





Form 8-K



Current Report Pursuant
to Section 13 or 15(d) of the
Securities Exchange Act of 1934



Date of report (Date of earliest event reported):  June 12, 1996



Aprogenex, Inc.
(Exact Name of Registrant as Specified in Its Charter)



Delaware
(State or Other Jurisdiction of Incorporation)

	1-12416	76-0269632
	(Commission File Number)	(I.R.S. Employer 
Identification No.)

	8000 El Rio Street, Houston, Texas	77054
	(Address of Principal Executive Offices)	(Zip Code)

(713) 748-5114
(Registrant's Telephone Number, Including Area Code)





Item 5.  Other Events
On June 12, 1996, Aprogenex, Inc. (the "Company") completed the 
sale of $2,005,000 of convertible notes (the "Notes") and warrants 
to acquire 130,323 shares of Common Stock, $.001 par value (the 
"1996 Warrants") in a private placement.  The following sections 
describe certain of the principal terms of the transaction and the 
securities.

Principal Terms of the Convertible Notes.  On June 12, 1996, the 
Company issued $2,005,000 principal amount of Notes due on May 29, 
1998.  
The Notes bear interest at the rate of 10% per annum, based on a 
365 day year, compounded quarterly.  Interest is payable at 
maturity or upon prepayment.  
The Notes are convertible into Common Stock at the option of the 
holder at any time after the earlier of (i) the approval for 
listing by the American Stock Exchange (the "AMEX") of the Common 
Stock issuable upon conversion of the Notes, or (ii) if the Common 
Stock of the Company ceases to be listed for trading on the AMEX, 
on the day of such de-listing.  However, the Notes may not be 
converted after the close of business on the fifth business day 
prior to either the scheduled maturity or any scheduled 
redemption.  
The Notes are convertible into Common Stock at a rate of one share 
of Common Sock for every $1.10 in principal and accrued interest 
(the "Conversion Price").  Accordingly, the Notes are initially 
convertible into a total of 1,822,727 shares of Common Stock, but 
such number of shares will increase as a result of interest on the 
Notes and may be further adjusted by changes in the Conversion 
Price as set forth herein.  All or part of the principal amount of 
the Notes may be converted at the election of the holder, but 
accrued interest applicable to the converted principal amount will 
also be converted into Common Stock.
On the twentieth business day prior to the maturity date of the 
Notes (the "Reset Date"), the Conversion Price will be adjusted to 
the average of the closing price of the Common Stock on the AMEX 
(or such other trading forum as may be applicable at that time) 
for the ten trading days prior to the Reset Date (the "Reset 
Conversion Price") if and only if such new Reset Conversion Price 
is lower than the then-current Conversion Price.  However, such 
price shall not be less than 50% of the then-Conversion Price.
The Notes contain provisions to protect the holders against 
dilution by adjusting the number of shares issuable upon 
conversion thereof.
The Company has the right to prepay principal and accrued interest 
upon twenty days notice to the holders of the Notes.  However, the 
holders have the right to convert the Notes  into Common Stock as 
set forth above prior to such redemption.
On or prior to August 11, 1996, the Company intends to file a 
Registration Statement on Form S-3 to register the resale of 
Common Stock issuable upon conversion of the Notes.  See 
"Registration of Additional Securities" herein.
The principal and accrued interest of the Note become immediately 
due and payable upon the insolvency of the Company, the commission 
of any act of bankruptcy by the Company, the execution by the 
Company of a general assignment for the benefit of creditors, the 
filing by or against the Company of any petition in bankruptcy or 
any petition for relief under the provisions of the federal 
bankruptcy act or any other state or federal law for the relief of 
debtors and the continuation of such petition without dismissal 
for a period of thirty (30) days or more, or the appointment of a 
receiver or trustee to take possession of the property or assets 
of the Company. 
Principal Terms of the 1996 Warrants.  Warrants to acquire 130,323 
shares of Common Stock were issued in conjunction with the Notes, 
or warrants for approximately 6,500 shares for every $100,000 of 
principal.
The 1996 Warrants entitle the holders thereof to purchase Common 
Stock at $1.10 per share and are exercisable at any time after the 
earlier of (i) the approval for listing by the American Stock 
Exchange (the "AMEX") of the Common Stock issuable upon exercise 
of the warrants, or (ii) if the Common Stock of the Company ceases 
to be listed for trading on the AMEX, on the day of such de-
listing, but such exercise must occur prior to the close of 
business on May 28, 1999.  The 1996 Warrants contain provisions to 
protect the holders thereof against dilution by adjusting the 
price at which the 1996 Warrants are exercisable and the number of 
shares issuable upon exercise thereof upon the occurrence of 
certain events.  Commencing September 10, 1996, the holders of the 
May Warrants will have "piggyback" registration rights to require 
the Company to include the Common Stock underlying such warrants 
in certain registration statements filed by the Company.

Purchases by Affiliates.  A substantial part of the Notes and 1996 
Warrants were purchased by existing stockholders and affiliates of 
the Company.  W.S. Farish and Company purchased $1,170,000 of 
Notes and 1996 Warrants to acquire 76,050 shares of Common Stock.  
W.S. Farish and Company was the beneficial owner of approximately 
9.3% of the outstanding Common Stock prior to the purchase.  This 
purchase will increase the beneficial ownership of W.S. Farish and 
Company to approximately 25.5% as of June 12, 1996.  Terry Ward is 
the Financial Vice President of W.S. Farish and Company, and is a 
director and Chairman of the Board of the Company.  Mr. Ward 
purchased $70,000 of Notes and 1996 Warrants to acquire 4,550 
shares of Common Stock.  Including the shares beneficially owned 
by W.S. Farish and Company, Mr. Ward beneficially owned 9.8% of 
the Common Stock of the Company prior to the purchase and 26.8% of 
the Common Stock after the purchase.  Mr. Ward disclaims such 
beneficial ownership of securities owned by W.S. Farish and 
Company.  Additionally, Mr. W.S. Farish  and members of his family 
acquired $150,000 of the Notes and 1996 Warrants to acquire 9,750 
shares of Common Stock.  Mr. Farish is a director and stockholder 
in W.S. Farish and Company.  Further information with respect to 
the security ownership of purchasers of Notes and 1996 Warrants 
may be available through any filings of these parties pursuant to 
the Securities and Exchange Act of 1934.

Net Proceeds From the Offering.  The net proceeds from the sale of 
the Notes and the 1996 warrants totaled approximately $1.8 million 
after deducting the estimated expenses and fees related to the 
offering.  The Company expects the proceeds from the sale to fund 
its normal operations through 1996.  See "Forward-Looking 
Statements" herein.
The Company has assigned a value of approximately $.50 per share 
of Common Stock to the 1996 Warrants, or a total of $65,000.  This 
valuation was based on review of the trading history of the Common 
Stock, the non-transferable provisions of the 1996 Warrants, and 
various other factors.  The value assigned to the 1996 Warrants 
will be treated as issue discount on the Notes and amortized as 
additional interest on the Notes.  Such amortization will increase 
the effective interest rate on the Notes to approximately 11.7%, 
assuming the Notes remain outstanding until maturity.

Press Release.  On June 13, 1996, Aprogenex, Inc. (the "Company") 
released a press release that included a description of the 
Company's private placement activities and cash resources.  The 
text of the release is attached as Exhibit 99.1 to this Form 8-K 
and is incorporated by reference.

Registration of Additional Securities.  On or prior to August 11, 
1996, the Company intends to file a Registration Statement on Form 
S-3 to register the resale of Common Stock issuable upon 
conversion of the Notes.  Certain holders of unregistered Common 
Stock or securities of the Company to acquire Common Stock issued 
by the Company prior to 1996 (collectively, the "Unregistered 
Securities") have the right to have the Unregistered Securities 
included in such Registration Statement.  The Company expects 
certain of these holders of Unregistered Securities, including 
certain affiliates of the Company, to exercise their right to 
register the resale of all or part of their Unregistered 
Securities.  The registration of such Unregistered Securities will 
reduce the restrictions on resale of such Common Stock, and such 
Common Stock could be sold during the time that the Registration 
Statement is effective.  The sale of such Unregistered Securities 
pursuant to the Registration Statement could have an adverse 
affect on the trading price of the Common Stock of the Company.

Adjustments to Preferred Stock and Other Warrants.  As a result of 
the sale of the Notes and the 1996 Warrants, there were changes in 
the exercise price and number of shares for which warrants were 
exercisable pursuant to the anti-dilution provisions of certain of 
the Company's outstanding warrants.  As a result of such 
adjustments, warrants for 110,941 shares exercisable at $7.39 per 
share increased to 144,586 shares exercisable at $5.67 per share, 
warrants for 12,093 shares exercisable at $9.54 per share 
increased to 15,951 shares exercisable at $7.24 per share, and 
warrants for 111,100 shares exercisable at $10.63 per share 
increased to 147,424 shares exercisable at $8.01 per share.
Additionally, as a result of the sale, the conversion rate of the 
Company's outstanding Series A Convertible Preferred Stock 
increased from 4.26 shares to 4.98 shares of Common Stock for 
every share of Series A Convertible Preferred Stock (or a decrease 
in the conversion price from $2.35 to $2.01 per share).  
Additionally, the Company's outstanding warrants to acquire 45,900 
shares of Series A Convertible Preferred Stock will benefit from 
the same increase in conversion rate.

Forward looking Statements.  The statements contained in this 
document regarding future cash uses and requirements, expected 
expenditure levels and other statements which are not historical 
facts are forward-looking statements that involve risks and 
uncertainties.  While various factors will influence the outcome 
of these forward-looking statements, the principal factors, among 
others, that will affect the uses of cash during 1996 included the 
progress or results of the Company's development activities, 
including any need for additional capital equipment, personnel or 
consultants or revisions to product development activities that 
may arise from interim results of such activities; competition in 
the marketplace, including the various factors that may affect 
sales of the Company's research products or the need to alter 
research plans or development activities to respond to competition 
or technological changes; collaborative relationships with others 
that may alter existing plans; retention of key personnel and the 
need to expend resources to replace such individuals; any 
litigation that may arise; and the need to expend resources on 
seeking additional financing.  
Additional factors to consider in assessing the risks and 
uncertainties of such forward-looking statements include, but are 
not limited to, those relating to: the Company's products being in 
the early stage of development; uncertainty of developing markets; 
the need for additional financing and limited access to capital 
funding; the Company's limited operating history; its accumulated 
deficit and anticipated losses; government regulation (including 
that the Company's products are subject to extensive regulation 
and required government approvals, that there is no assurance of 
regulatory approvals and that failure to obtain such approvals 
will have an adverse effect; uncertainty of the type of, timing or 
receipt of FDA approval; that the Company will be subject to 
numerous international regulations and that other regulations may 
adversely affect the Company); the Company's reliance on 
distributors and collaborative partners; license patents and trade 
secrets (including the uncertainty of domestic and international 
patent protection, the possibility of patent infringement claims 
against the Company, the Company's reliance on trade secrets and 
proprietary know-how and that there is no assurance of 
confidentiality); the potential adverse effects of technological 
change and competition; potential of limited third-party 
reimbursement; use of hazardous materials; possibility of product 
liability claims; dependence on key personnel; limited 
manufacturing and marketing experience; uncertainty relating to 
health care reform measures; and other factors detailed in the 
Company's Securities and Exchange Commission filings. 


Item 7.  Financial Statements and Exhibits
	(b.)  Exhibits

Exhibit				
Number	Document Description

4.1(a)	Convertible Note Subscription Agreement dated as of 
May 1, 1996 among Aprogenex, Inc. and the various 
purchasers.

4.1(b)	Form of Convertible Note dated as of June 12, 1996.

4.2	Warrant Agreement dated as of May 1, 1996 among 
Aprogenex, Inc. and the various warrantholders.

99.1	Press Release dated June 13, 1996.




SIGNATURES

	Pursuant to the requirements of the Securities Exchange Act 
of 1934, the registrant has duly caused this report to be signed 
on its behalf by the undersigned hereunto duly authorized.

	APROGENEX, INC.


DATE: June 25, 1996	BY:	  /s/ J. Donald Payne	
		J. Donald Payne
Vice President - Finance and 
Chief Financial Officer 

Exhibit Index


Exhibit				
Number	Document Description


4.1(a)	Convertible Note Subscription Agreement dated as of 
May 1, 1996 among Aprogenex, Inc. and the various 
purchasers.

4.1(b)	Form of Convertible Note dated as of June 12, 1996.

4.2	Warrant Agreement dated as of May 1, 1996 among 
Aprogenex, Inc. and the various warrantholders.

99.1	Press Release dated June 13, 1996.



 




Exhibit 4.1(a)

CONVERTIBLE NOTE SUBSCRIPTION AGREEMENT


THIS CONVERTIBLE NOTE SUBSCRIPTION AGREEMENT (the Agreement) is 
made as of May 1, 1996, by and among APROGENEX, INC., a Delaware 
corporation (the Company), and those persons set forth on 
Exhibit A (the Purchasers).

SECTION 1
Authorization and Sale of Convertible Note

1.1  Authorization.  The Company has authorized the sale and 
issuance of up to an aggregate of $5 million principal amount of 
10% convertible notes due 1998 (the Notes) and has reserved such 
number of shares (the Conversion Shares) of Common Stock par value 
$.001 per share of the Company (the Common Stock) as shall 
initially be required for issuance upon conversion of the Notes.  
The Company reserves the right in its sole discretion to reject 
any or all subscriptions, in whole or in part, for any reason,  
and to allocate any Notes among Purchasers.

1.2  Sale of Convertible Notes..  Subject to the terms and 
conditions hereof, the Company will issue and sell to the 
Purchasers and the Purchasers severally will buy from the Company: 
(a) the Notes in the respective principal amounts set forth 
opposite each Purchaser's name on Exhibit A at a purchase price 
set forth on Exhibit A; and (b) the number of warrants (the 
Warrants) in the respective amounts of Warrants set forth opposite 
each Purchaser's name on Exhibit A.  Each Warrant entitles the 
holder to purchase one share of Common Stock and shall be in the 
form attached to the warrant agreement (the Warrant Agreement) set 
forth on Exhibit B.   The Notes and the Warrants are together 
referred to herein as Securities. 

1.3  Payment into Escrow.  Upon execution of this Agreement, the 
Purchasers shall submit to the Company a check drawn on a bank 
acceptable to the Company payable to Chemical Bank, Escrow Agent 
F/B/O Aprogenex, Inc. in the amount of the applicable purchase 
price.  The Company shall promptly deliver to the Escrow Agent 
such funds which the Escrow Agent shall maintain in an interest 
bearing bank account pending the closing of the sale of the Notes 
hereunder (the Closing), pursuant to the terms of the form of 
Escrow Agreement set forth on Exhibit C hereto (the Escrow 
Agreement).

SECTION 2
Closing Date; Delivery

2.1  Closing Date..  The Closing shall take place at the offices 
of Baker & Botts, L.L.P., 599 Lexington Avenue, New York, New York 
10022 on May 15, 1996 or at such other times, dates and places 
upon which the Company and the Purchasers shall mutually agree 
(the date of the Closing is hereinafter referred to as the Closing 
Date).  In the event that the Company has not received cash 
subscriptions for at least an aggregate of $2 million principal 
amount of Notes by the Closing Date, the purchase price, with any 
interest earned on the purchase price, shall be returned to the 
Purchasers.  If the Company receives subscriptions for at least an 
aggregate of $2 million principal amount of Notes on or prior to 
the Closing Date, then the Closing will take place.  It is 
understood that affiliates of the Company may purchase Notes in 
the offering in an amount sufficient to achieve such minimum 
subscription.

2.2  Delivery.. At the Closing, the Company will deliver to the 
Escrow Agent certificates representing the Notes and the Warrants.  
The Escrow Agent shall thereupon disburse certificates to the 
Purchasers and shall disburse to the Company the aggregate 
purchase price in immediately available funds, all in accordance 
with the Escrow Agreement.  (The date of such disbursement is 
referred to herein as the Disbursement Date.)  The certificates 
for Notes shall be subject to a legend restricting transfer under 
the Securities Act of 1933, as amended (the Securities Act), and 
applicable state laws, and referring to restrictions on transfer 
herein, such legend to be substantially as follows:

THE SECURITIES EVIDENCED HEREBY HAVE BEEN ACQUIRED FOR 
INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE 
SECURITIES ACT OF 1933, AS AMENDED OR ANY STATE SECURITIES 
LAWS. NO SALE OR DISPOSITION MAY BE EFFECTED WITHOUT (i) 
EFFECTIVE REGISTRATION STATEMENTS RELATED THERETO, (ii) AN 
OPINION OF COUNSEL FOR THE INVESTOR, REASONABLY 
SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATIONS ARE NOT 
REQUIRED AND THAT ANY APPLICABLE  PROSPECTUS DELIVERY 
REQUIREMENTS ARE NOT APPLICABLE OR (iii) RECEIPT OF NO-
ACTION LETTERS FROM THE APPROPRIATE GOVERNMENTAL 
AUTHORITIES. THESE SECURITIES WERE OBTAINED FROM THE 
COMPANY UNDER AN AGREEMENT THAT INCLUDES ADDITIONAL 
RESTRICTIONS ON TRANSFER AND COPIES OF SUCH AGREEMENT MAY 
BE OBTAINED AT NO COST BY WRITTEN REQUEST MADE BY THE 
HOLDER OF RECORD OF THIS CERTIFICATE TO THE SECRETARY OF 
THE COMPANY AT THE PRINCIPAL EXECUTIVE OFFICES OF THE 
COMPANY.

The Notes may also include any legend required under the laws of 
any state or other jurisdiction. The certificates for Warrants and 
for the shares of Common Stock issuable upon exercise of the 
Warrants (the Warrant Shares)  will include such legend as is 
specified in the Warrant Agreement. The certificates representing 
the Conversion Shares will also include the aforementioned legends 
and any other appropriate legend.

SECTION 3
Representations and Warranties of the Company

Except as set forth on the Schedule of Exceptions attached hereto 
as Exhibit D, the Company hereby represents and warrants to the 
Purchasers as follows:

3.1  Organization.  The Company is a corporation duly organized 
and validly existing under the laws of the State of Delaware and 
is in good standing under such laws.  The Company has requisite 
corporate power and authority to own, lease and operate its 
properties and assets, and to carry on its business as presently 
conducted and as proposed to be conducted.  The Company is 
qualified to do business as a foreign corporation in each 
jurisdiction in which the ownership of its property or the nature 
of its business requires such qualification, except where failure 
to so qualify would not have a material adverse effect on the 
Company.  The Company has no subsidiaries.

3.2  Capitalization.  The authorized capital stock of the Company 
consists of 20,000,000 shares of Common Stock, $.001 par value per 
share, of which 5,200,598 shares were issued and outstanding as of 
March 31, 1996, and 11,200,000 shares of Preferred Stock, $.001 
par value per share, of which 880,000 shares have been designated 
as Series A Convertible Preferred Stock and of which 449,000 
shares were issued and outstanding as of March 31, 1996.  All such 
issued and outstanding shares of Common Stock have been duly 
authorized and validly issued and are fully paid and 
nonassessable.  As of March 31, 1996, the Company had 523,407 
shares of Common Stock reserved for issuance under its 1990 Stock 
Option Plan and options to purchase 355,529  shares of Common 
Stock thereunder have been granted and are outstanding.  As of 
March 31, 1996, the Company had 100,000 shares of Common Stock 
reserved for issuance under its Directors Stock Option Plan and 
options to purchase 51,200 shares of Common Stock thereunder have 
been granted and are outstanding.  The Company has outstanding, as 
of March 31, 1996, warrants to purchase 373,873 shares of Common 
Stock and warrants to purchase 45,900 shares of Series A 
Convertible Preferred Stock, which warrants will be subject to 
further adjustment for antidilution provisions. Except as provided 
in the materials delivered to the Purchasers by the Company 
pursuant to this Agreement, which materials include the Company's 
Annual Report on Form 10-KSB for the year ended December 31, 1995, 
the Company's Current Report on Form 8-K dated April 1, 1996 and 
the Additional Information dated May 1, 1996 (collectively the 
Offering Materials) or as described in this Agreement, there are 
no other options, warrants, conversion privileges or other 
contractual rights presently outstanding to purchase or otherwise 
acquire any authorized but unissued shares of the Company's 
capital stock or other securities other than the Securities.

3.3  Authorization.  The Company has all corporate right, power 
and authority to enter into this Agreement and to consummate the 
transactions contemplated hereby.  All corporate action on the 
part of the Company, its directors and stockholders necessary for 
the authorization, execution, delivery and performance of this 
Agreement by the Company, the authorization, sale, issuance and 
delivery of the Securities, the Conversion Shares and the Warrant 
Shares and the performance of the Company's obligations hereunder 
has been taken.  This Agreement has been duly executed and 
delivered by the Company and constitutes a legal, valid and 
binding obligation of the Company, enforceable against the Company 
in accordance with its terms, subject to laws of general 
application relating to bankruptcy, insolvency and the relief of 
debtors and rules of law governing specific performance, 
injunctive relief or other equitable remedies, and to limitations 
of public policy.  Upon the issuance and delivery of the Notes as 
contemplated by this Agreement, the Notes will be validly issued.  
Upon the approval of the Warrant Shares for listing on the AMEX 
and the issuance and delivery of the Warrant Shares upon exercise 
of the Warrants in accordance with the Warrant Agreement, the 
Warrant Shares will be validly issued, fully paid and 
nonassessable.   Upon the approval of the Conversation Shares for 
listing on the AMEX and the issuance and delivery of the 
Conversion Shares upon conversion of the Notes, the Conversion 
Shares will be validly issued, fully paid and nonassessable.  The 
issuance and sale of the Notes contemplated hereby, the Warrant 
Shares and the Conversion Shares will not give rise to any 
preemptive rights or rights of first refusal on behalf of any 
person.

3.4  No Conflict.  Subject to compliance with such filings as may 
be required to be made with the Securities and Exchange Commission 
(the SEC), any state or foreign securities regulatory authority, 
and the American Stock Exchange (AMEX), the execution and delivery 
of this Agreement does not, and the consummation of the 
transactions contemplated hereby will not result in any violation 
of, or default (with or without notice or lapse of time, or both), 
or give rise to a right of termination, cancellation or 
acceleration of any material obligation or to a loss of a material 
benefit, under, any provision of the Amended and Restated 
Certificate of Incorporation or Bylaws of the Company or any 
mortgage, indenture, lease or other agreement or instrument, 
license, judgment, order, decree, statute, law, ordinance, rule or 
regulation applicable to the Company, its properties or assets, 
the effect of which would have a material adverse effect on the 
Company, its financial condition, results of operation or 
prospects, or materially impair or restrict its power to perform 
its obligations as contemplated hereby. Notwithstanding any other 
provisions of this Agreement, the issuance of the Conversion 
Shares and the Warrant Shares will require the approval of the 
AMEX which approval the Company will seek to obtain promptly 
following the Closing.

3.5  Accuracy of Reports.  All reports currently required to be 
filed by the Company since the beginning of its most recent fiscal 
year under the Securities Exchange Act of 1934, as amended (the 
Exchange Act), copies of which the Company and the Purchaser 
acknowledge  have been furnished to the Purchaser, have been duly 
filed with the SEC, complied at the time of filing in all material 
respects with the requirements of their respective forms, and, 
except to the extent updated or superseded by the Offering 
Materials or any subsequently filed report, were complete and 
correct in all material respects as of the dates at which the 
information was furnished, and contained (as of such dates) no 
untrue statement of a material fact or omitted to state a material 
fact necessary in order to make the statements contained therein, 
in light of the circumstances under which they were made, not 
misleading.

3.6  Registration Rights.  Except as set forth in this Agreement 
and the Warrant Agreement, the Company is not under any obligation 
to register any of its presently outstanding securities or any of 
its securities which may hereafter be issued other than under the 
Amended and Restated Stockholders' Agreement among the Company and 
certain of its security holders dated as of June 8, 1993, as 
amended by Amendment No. 1 dated as of April 29, 1994, the 
Representative's Warrant Agreement between the Company and H. J. 
Meyers & Co., Inc. dated as of October 22, 1993 and under the 
Registration Rights Agreement dated April 21, 1994 between the 
Company and MediGene, Inc., the Warrant Agreement dated March 15, 
1995, the Common Stock Purchase Agreement dated as of March 15, 
1995 between the Company and the purchasers named therein, and the 
Premium Preferred Stock Purchase Agreements dated as of May 26, 
1995 among the Company and the purchasers named therein.  The 
Company currently has outstanding two registration statements that 
were filed in respect of certain of the aforementioned 
registration rights.  The Company expects to engage in various 
capital-raising efforts in the future that, if consummated, would 
require the granting of additional registration rights.

3.7  Governmental Consents, etc.  No consent, approval or 
authorization of or designation, declaration or filing with any 
governmental authority on the part of the Company is required in 
connection with the execution and delivery of this Agreement, the 
offer, sale or issuance of the Notes, or the consummation of any 
other transaction contemplated hereby, except such filings as may 
be required to be made with the SEC and the AMEX and with any 
state or foreign blue sky or securities regulatory authority.

3.8  Litigation.  There is no pending or, to the best of the 
Company's knowledge, threatened lawsuit, administrative 
proceeding, arbitration, labor dispute or governmental 
investigation (Litigation) to which the Company is a party or by 
which any material portion of its assets taken as a whole may be 
bound, and which Litigation if adversely determined would have a 
material adverse effect on the Company.

3.9  Investment Company.  The Company is not an investment company 
within the meaning of such term under the Investment Company Act 
of 1940 and the rules and regulations of the SEC thereunder.

3.10  Intellectual Property.  With respect to each of the 
Company's material patents and patent applications licensed, used 
or applied for by the Company in connection with the operation of 
the Company's business (collectively, the Intangibles), to the 
best of the Company's actual knowledge (i) the Company has all 
licenses or rights which it believes are necessary to use the 
Intangibles, (ii) the inventor(s) named in each of the patents and 
patent applications comprising the Intangibles are the only 
inventor(s) of the subject matter claimed in such Intangibles, 
(iii) no adverse claim of ownership has been asserted against the 
Company with respect to the subject matter claimed in the 
Intangibles and (iv) the Company has not infringed with respect to 
patents of others and the Company has not received notice of 
infringement with respect to patents of others.

3.11  Regulatory Filings.  The Company believes that it has the 
authority to conduct its operations as presently described in the 
Offering Materials; however, the Company has not received approval 
from the Food and Drug Administration or other regulatory 
authorities for, nor are any filings pending with such agencies 
for, any registrations, applications, licenses, requests for 
exemptions, permits and other regulatory authorizations.

3.12  Private Offering Materials; Disclosure.  No information set 
forth in the Offering Materials or otherwise provided by the 
Company to the Purchasers in connection with their purchase of the 
Notes contains any untrue statement of a material fact or omits to 
state a material fact necessary in order to make the statements 
contained therein, in light of the circumstances under which they 
were made, not misleading.

SECTION 4
Representations and Warranties of the Purchasers

The Purchasers each hereby severally represent and warrant to the 
Company as follows:

4.1  Purchase for Investment.  The Purchaser is acquiring the 
Notes and the Conversion Shares for investment for its own 
account, not as a nominee or agent, and not with a view to, or for 
resale in connection with, any distribution thereof.  The 
Purchaser acknowledges the Company's obligation to file a 
registration statement with respect to the Conversion Shares as 
set forth in Section 8 of this Agreement, the effectiveness of 
which registration statement may be required for the resale of the 
Conversion Shares.  Without limiting the generality of the first 
sentence of this Section, the Purchaser has not offered or sold 
any portion of the Notes and the Conversion Shares to be acquired 
by it and has no present intention of reselling or otherwise 
disposing of any portion of such Notes or Conversion Shares either 
currently or after the passage of a fixed or determinable period 
of time or upon the occurrence or nonoccurrence of any 
predetermined event or circumstance, and in particular the 
Purchaser has no current intention to resell the Conversion Shares 
under such registration statement nor would it have such intention 
if such registration statement were effective as of the date of 
purchase.  It understands that investment in the Notes is subject 
to a high degree of risk and that the Notes and the Conversion 
Shares have not been registered under the Securities Act, by 
reason of a specific exemption from the registration provisions of 
the Securities Act which depends upon, among other things, the 
bona fide nature of Purchaser's investment intent and the accuracy 
of the Purchaser's representations as expressed herein.  It 
acknowledges and understands that it must bear the economic risk 
of this investment for an indefinite period of time because the 
Notes and Conversion Shares must be held indefinitely until 
subsequently registered under the Securities Act and applicable 
state and other securities laws or unless an exemption from 
registration is available.  It understands that any transfer agent 
of the Company will be issued stop-transfer instructions with 
respect to the Conversion Shares unless such transfer is 
subsequently registered under the Securities Act and applicable 
state and other securities laws or unless an exemption from such 
registration is available.  The Purchaser has experience in 
analyzing and investing in entities like the Company, it can bear 
the economic risk of its investment, including the full loss of 
its investment, and by reason of its business or financial 
experience or the business or financial experience of its 
professional advisors has the capacity to evaluate the merits and 
risks of its investment and protect its own interest in connection 
with the purchase of the Notes from the Company at the Closing.  
The Purchaser is a resident of the state set forth opposite such 
Purchaser's name on Exhibit A.  The Purchaser represents that it 
does not have any contract, undertaking, agreement or arrangement 
with any person to sell, transfer or grant participation to such 
person or to any third person, with respect to any of the Notes or 
Conversion Shares.  If other than an individual, it also 
represents it has not been organized for the purpose of acquiring 
the Notes.  The Purchaser's purchase is not and will not be part 
of a plan or scheme to evade the registration requirements of the 
Securities Act or any other law or regulation.

4.2  Accredited Investor.  The Purchaser is an accredited investor 
as such term is defined in SEC Regulation D.  It has accurately 
completed the questionnaire attached hereto as Exhibit E.

4.3  Authority.  The Purchaser has all right, power and authority 
to enter into this Agreement and to consummate the transactions 
contemplated hereby.  This Agreement has been duly executed and 
delivered by the Purchaser and constitutes a legal, valid and 
binding obligation of the Purchaser, enforceable against the 
Purchaser in accordance with its terms, subject to laws of general 
application relating to bankruptcy, insolvency and the relief of 
debtors and rules of law governing specific performance, 
injunctive relief or other equitable remedies, and to limitations 
of public policy.  Subject to compliance with such filings as may 
be required to be made with the SEC, AMEX and National Association 
of Securities Dealers Inc. (NASD), the execution and delivery of 
this Agreement do not, and the consummation of the transactions 
contemplated hereby will not, conflict with or result in any 
violation of any obligation under any provision of the charter 
documents, partnership agreement or Bylaws, if any, of the 
Purchaser or any mortgage, indenture, lease or other agreement or 
instrument, license, judgment, order, decree, statute, law, 
ordinance, rule or regulation applicable to the Purchaser.

4.4  Government Consents, etc.  No consent, approval or 
authorization of or designation, declaration or filing with any 
governmental authority on the part of the Purchaser is required in 
connection with the valid execution and delivery of this 
Agreement, the purchase of the Notes, or the consummation of any 
other transaction contemplated hereby, except such filings as may 
be required to be made with the SEC, AMEX and NASD.

4.5  Investigation; No General Solicitation.  The Purchaser has 
received a copy of the Offering Materials.  The Purchaser has had 
a reasonable opportunity to ask questions relating to and 
otherwise discuss the terms and conditions of the offering and the 
other information set forth in the Offering Materials and the 
Company's business, management and financial affairs with the 
Company's management, customers and other parties, and the 
Purchaser has received satisfactory responses to the Purchaser's 
inquiries.  The Purchaser has relied solely upon the information 
provided by the Company in the Offering Materials in making the 
decision to invest in the Notes. To the extent necessary, the 
Purchaser has retained, at the expense of the Purchaser, and 
relied upon appropriate professional advice regarding the 
investment, tax and legal merits and consequences of this 
Agreement and the purchase of the Notes hereunder.  To the best of 
its knowledge, (i) the Purchaser was contacted regarding the sale 
of the Securities by the Company (or an authorized agent or 
representative thereof) with whom the Purchaser had a prior 
relationship and (ii) no securities were offered or sold to it by 
means of any form of general solicitation or general advertising, 
and in connection therewith the Purchaser:  did not (A) receive or 
review any advertisement, article, notice or other communication 
published in a newspaper or magazine or similar media or broadcast 
over television or radio whether closed circuit, or generally 
available; or (B) attend any seminar meeting or industry investor 
conference whose attendees were invited by any general 
solicitation or general advertising.

4.6  Short Selling.  The Purchaser has not, for the 60 days prior 
to the date hereof, directly or indirectly, through related 
parties, affiliates or otherwise (a) sold short or short against 
the box (as those terms are generally understood) any equity 
security of the Company; or (b) otherwise engaged in any 
transaction which involves hedging of its position in the 
securities of the Company, and it will not either (x)  until the 
date the Registration Statement (as defined herein) is declared 
effective by the SEC or (y) during the 30 days prior to the 
maturity of the Notes take any such actions in (a) or (b).

4.7  Qualification.  The Purchaser is qualified to purchase the 
Securities and Conversion Shares under the laws of the Purchaser'
s 
residence, and such purchase complies with such laws and any other 
laws applicable to the Purchaser.

4.8  Affiliate Status.  Except as otherwise disclosed in writing 
to the Company: (i) the Purchaser is not, and has not been within 
the 90 days prior to the Closing Date, an officer, director, 
employee, agent or affiliate of the Company, a broker/dealer of 
securities or, to the Purchaser's knowledge, any other purchaser 
of Notes from the Company pursuant to the Offering Materials; and 
(ii) the Purchaser is not a broker or dealer of securities, an 
employee, officer or director of the Company nor prior to the 
consummation of the transactions contemplated hereby, is the 
Purchaser the beneficial owner of 5% or more of the Common Stock 
of the Company.

SECTION 5
Conditions to Obligations of the Purchasers

5.1  Conditions to Obligations of the Purchasers.  The Purchasers' 
obligation to purchase the Notes at the Closing is, at the option 
of each Purchaser, which may waive any such conditions to the 
extent permitted by law, subject to the fulfillment on or prior to 
the Closing Date of the following conditions:

(a)  Representations and Warranties Correct.  The representations 
and warranties made by the Company in Section 3 hereof shall be 
true and correct in all material respects when made, and shall be 
true and correct in all material respects on the Closing Date with 
the same force and effect as if they had been made on and as of 
said date.

(b)  Covenants.  All covenants, agreements and conditions 
contained in this Agreement to be performed by the Company on or 
prior to such purchase shall have been performed or complied with 
in all material respects.

(c)  No Legal Order Pending.  There shall not then be in effect 
any legal or other order enjoining or restraining the transactions 
contemplated by this Agreement.

(d)  No Law Prohibiting or Restricting Such Sale.  There shall not 
be in effect any law, rule or regulation prohibiting or 
restricting such sale or requiring any consent or approval of any 
person which shall not have been obtained to issue the Shares 
(except as otherwise provided in this Agreement).

(e)  Minimum Subscriptions.  The Company shall have received 
executed Agreements from Purchasers, payments into escrow and any 
other necessary related materials to enable it to sell at least an 
aggregate of $2 million principal amount of Notes.


SECTION 6
Conditions to Obligations of Company

6.1  Conditions to Obligations of Company.  The Company's 
obligation to sell and issue the Shares at the Closing is, at the 
option of the Company, which may waive any such conditions to the 
extent permitted by law, subject to the fulfillment on or prior to 
the Closing Date of the following conditions:

(a)  Representations and Warranties Correct.  The representations 
and warranties made by the Purchasers in Section 4 hereof shall be 
true and correct in all material respects when made, and shall be 
true and correct in all material respects on the Closing Date with 
the same force and effect as if they had been made on and as of 
said date.

(b)  Covenants.  All covenants, agreements and conditions 
contained in this Agreement to be performed by the Purchasers on 
or prior to the Closing Date shall have been performed or complied 
with in all material respects.

(c)  No Legal Order Pending.  There shall not then be in effect 
any legal or other order enjoining or restraining the transactions 
contemplated by this Agreement.

(d)  No Law Prohibiting or Restricting Such Sale.  There shall not 
be in effect any law, rule or regulation prohibiting or 
restricting such sale or requiring any consent or approval of any 
person which shall not have been obtained to issue the Notes 
(except as otherwise provided in this Agreement).

(e)  Minimum Subscription.  The Company shall have received 
executed Agreements from Purchasers, payments into escrow and any 
necessary related materials to enable it to sell at least $2 
million aggregate principal amount of Notes.

SECTION 7
Definitions

7.1  Certain Definitions.  As used in this Agreement, the 
following terms shall have the following meanings:

(a)  Affiliate shall mean, with respect to any person, any other 
person controlling, controlled by or under direct or indirect 
common control with such person (for the purposes of this 
definition control, when used with respect to any specified 
person, shall mean the power to direct the management and policies 
of such person, directly or indirectly, whether through ownership 
of voting securities, by contract or otherwise; and the terms 
controlling and controlled shall have meanings correlative to the 
foregoing).

(b)  Business Day shall mean a day Monday through Friday on which 
banks are generally open for business in Texas.

(c)  Closing shall have the meaning ascribed to such term in 
Section 1.3.

(d)  Closing Date shall have the meaning ascribed to such term in 
Section 2.1.

(e)  Closing Price shall mean  the last sales price, regular way, 
on the day in question or, in case no such sale takes place on 
such day, the average of the closing bid and asked prices, regular 
way, on such day, in either case as reported in the principal 
transaction reporting system with respect to securities listed or 
admitted to trading on the AMEX, or, if such security is not 
listed or admitted to trading on the AMEX, on the principal 
national securities exchange on which such security is listed or 
admitted to trading, or, if such security is not listed or 
admitted to trading on any national securities exchange but sales 
price information is reported for such security, as reported by 
NASDAQ or such other self-regulatory organization or registered 
securities information processor (as such terms are used under the 
Securities Exchange Act of 1934, as amended) that then reports 
information concerning such security, or, if sales price 
information is not so reported, the average of the high bid and 
low asked prices in the over-the-counter market on such day, as 
reported by NASDAQ or such other entity, or, if on such day such 
security is not quoted by any such entity, the average of the 
closing bid and asked prices as furnished by a professional market 
maker making a market in such security selected by the Board of 
Directors of the Company.  If on such day no market maker is 
making a market in such security, the fair value of such security 
on such day as determined in good faith by the Board of Directors 
of the Company shall be used.

(f)  Company shall have the meaning ascribed to such term in the 
preamble hereto.

(g)  Conversion Shares shall have the meaning ascribed to such 
term in Section 1.1.

(h)  Escrow Agent shall mean Chemical Bank.

(i)  Fair Value shall have the meaning ascribed to such term in 
Section 10.7.

(j)  Highest Lawful Rate shall have the meaning ascribed to such 
term in Section 11.5.

(k)  Holders shall mean: (i) when used with respect to the Notes, 
the Purchasers and any Person holding any Note or Notes to whom 
such Note or Notes has been transferred in accordance with Section 
11.2 hereof and (ii) when used with respect to Registrable 
Securities, the Purchasers and any Person holding Registrable 
Securities to whom the rights under Section 8.1 have been 
transferred in accordance with Section 8.1(h) hereof.

(l)  Indemnified Party shall have the meaning ascribed to such 
term in Section 8.1(e).

(m) Indemnifying Party shall have the meaning ascribed to such 
term in Section 8.1(e).

(n)  Outstanding shall mean when used with respect to Notes, all 
Notes theretofore issued under this Agreement, except: (i) Notes 
theretofore canceled and delivered to the Company or delivered to 
the Company for cancellation; (ii) Notes for whom payment or 
redemption money in the necessary amount has been theretofore 
deposited with any paying agent for the Company in trust for the 
Holders of such Notes, provided that, if such Notes are to be 
redeemed, notice of such redemption has been duly given pursuant 
to this Agreement; and (iii) Notes in exchange for or in lieu of 
which other Notes have been issued pursuant to  this Agreement; 
provided, however, that in determining whether the Holders of the 
requisite principal amount of Notes Outstanding have given any 
request, demand, authorization, direction, notice, consent or 
waiver hereunder,  Notes owned by the Company shall be disregarded 
and deemed not to be Outstanding; provided, however, that 
notwithstanding the foregoing proviso, Notes owned by any 
Affiliate of the Company (other than a subsidiary) shall be deemed 
to be Outstanding for all purposes.

(o)  Person shall mean any person, individual, corporation, 
partnership, trust or other nongovernmental entity or any 
governmental agency, court, authority or other body (whether 
foreign, federal, state, local or otherwise).

(p)  The terms register, registered and registration refer to the 
registration effected by preparing and filing a registration 
statement in compliance with the Securities Act, and the 
declaration or ordering of the effectiveness of such registration 
statement.

(q)  Purchasers shall have the meaning ascribed to such term in 
the preamble hereto.

(r)  Redemption Date shall have the meaning ascribed to such term 
in Section 9.1.

(s)  Redemption Price shall have the meaning ascribed to such term 
in Section 9.1.

(t)  Registrable Securities shall mean (A) the Conversion Shares, 
and (B) any shares of Common Stock issued as (or issuable upon the 
conversion of any warrant, right or other security which is issued 
as) a dividend or other distribution with respect to or in 
replacement of the Conversion Shares; provided, however, that 
securities shall only be treated as Registrable Securities if and 
only for so long as they (i) have not been disposed or pursuant to 
a registration statement declared effective by the SEC, (ii) have 
not been sold in a transaction exempt from the registration and 
prospectus delivery requirements of the Securities Act so that all 
transfer restrictions and restrictive legends with respect thereto 
are removed upon the consummation of such sale, or (iii) are held 
by a Holder or a permitted transferee pursuant to Section 8.1(h).

(u)  Registration Expenses shall mean all expenses incurred by the 
Company in complying with Section 8.1(a) hereof, including, 
without limitation, all registration, qualification and filing 
fees, printing expenses, escrow fees, fees and expenses of counsel 
for the Company, blue sky fees and expenses (for a reasonable 
number of states) and the expense of any special audits incident 
to or required by any such registration (but excluding the fees of 
legal counsel for any Holder).

(v)  Registration Statement shall have the meaning ascribed to 
such term in Section 8.1(a).

(w)  Registration Period shall have the meaning ascribed to such 
term in Section 8.1(c).

(x)  Reset Date shall have the meaning ascribed to such term in 
Section 10.1.

(y)  Securities shall have the meaning ascribed to such term in 
Section 1.2.

(z)  Selling Expenses shall mean all underwriting discounts and 
selling commissions applicable to the sale of Registrable 
Securities and all fees and expenses of legal counsel for any 
Holder.

(aa)  Stated Maturity when used with respect to any Note means the 
date specified in such Note as the fixed date on which the 
principal of such Note is due and payable.

(bb)  Warrant Shares shall have the meaning ascribed to such term 
in Section 2.2.

SECTION 8
Covenants

8.1  Registration Rights.

(a)  Registration.  No later than 60 days after the Closing Date, 
the Company will file a registration statement (the Registration 
Statement) on Form S-3 with the SEC and use its reasonable best 
efforts to effect the registration, qualifications or compliances 
(including, without limitation, the execution of any required 
undertaking to file post-effective amendments, appropriate 
qualifications under applicable blue sky or other state securities 
laws and appropriate compliance with applicable securities laws, 
requirements or regulations) as may be so reasonably requested and 
as would permit or facilitate the sale and distribution of all 
Registrable Securities; provided, however that the Company shall 
not be obligated to take any action to effect any such 
registration, qualification or compliance pursuant to this Section 
8.1(a) in any particular jurisdiction in which the Company would 
be required to execute a general consent to service of process in 
effecting such registration, qualification or compliance unless 
the Company is already subject to service or is required to 
qualify in such jurisdiction, as the case may be, and except as 
may be required by the Securities Act.  Without limiting the 
generality of any other provision hereof, this Agreement does not 
grant any registration rights for the registration of the transfer 
of the Notes, the Warrants or the Warrant Shares (the registration 
of the Warrant Shares being covered in the Warrant Agreement).

(b)  Expenses of Registration.  All Registration Expenses incurred 
in connection with any registration, qualification or compliance 
pursuant to Section 8.1(a) shall be borne by the Company.  All 
Selling Expenses relating to the sale of securities registered by 
or on behalf of Holders shall be borne by such Holders who 
directly incurred said expenses, except to the extent that the 
Holders may make separate arrangements for the sharing of 
expenses.  

(c)  Registration Procedures.  In the case of the registration, 
qualification or compliance effected by the Company pursuant to 
this Agreement, the Company will, upon reasonable request, inform 
each Holder as to the status of such registration, qualification 
and compliance.  At its expense the Company will:

	(i)  use its reasonable best efforts to keep such 
registration, and any qualification or compliance under state 
securities laws which the Company determines to obtain, effective 
until at least the second anniversary of the Closing Date or until 
the Holders have completed the distribution described in the 
registration statement relating thereto, whichever first occurs.

	(ii)  furnish such number of prospectuses and other documents 
incident thereto as the Holders from time to time may reasonably 
request.  

Notwithstanding any of the foregoing at the Company's election, 
the Company may cease to keep such registration, qualification or 
compliance effective with respect to any Registrable Securities, 
and the registration rights of a Holder shall expire, at such time 
as the Holder may sell under Rule 144 under the Securities Act (or 
other exemption from registration acceptable to the Company) in a 
three-month period all Registrable Securities then held by such 
Holder.  The period of time during which the Company is required 
hereunder to keep the Registration Statement effective is referred 
to herein as the Registration Period.

(d)  Delay of Registration.  The Holders shall have no right to 
take any action to restrain, enjoin or otherwise delay any 
registration pursuant to Section 8.1(a) hereof as a result of any 
controversy that may arise with respect to the interpretation or 
implementation of this Agreement.


(e)  Indemnification.

	(i)  The Company will indemnify each Holder, each of its 
officers, directors, employees, partners, legal counsel and 
accountants, and each person controlling such Holder within the 
meaning of Section 15 of the Securities Act, with respect to which 
any registration, qualification or compliance has been effected 
pursuant to this Agreement, and each person who controls any 
underwriter within the meaning of Section 15 of the Securities 
Act, against all expenses, claims, losses, damages and liabilities 
(or action in respect thereof), including any of the foregoing 
incurred in settlement of any litigation, commenced or threatened, 
arising out of or based on any untrue statement (or alleged untrue 
statement) of a material fact contained in any registration 
statement, prospectus, offering circular or other document, or any 
amendment or supplement thereof, incident to any such 
registration, qualification or compliance, or based on any 
omission (or alleged omission) to state therein a material fact 
required to be stated therein or necessary to make the statements 
therein not misleading, and will reimburse each Holder, each of 
its officers, directors, employees, partners, legal counsel and 
accountants, and each person controlling such Holder, and each 
person who controls any such underwriter, for reasonable legal and 
any other expenses reasonably incurred in connection with 
investigating, preparing or defending any such claim, loss, 
damage, liability or action as incurred, provided that the Company 
will not be liable in any such case to the extent that any untrue 
statement or omission or allegation thereof is made in reliance 
upon and in conformity with written information furnished to the 
Company by an instrument duly executed by or on behalf of such 
Holder and stated to be specifically for use in preparation of 
such registration statement, prospectus, offering circular or 
other document; and provided that the Company will not be liable 
in any such case where the expense, claim, loss, damage or 
liability arises out of or is related to the failure of the Holder 
to comply with the covenants and agreements contained in this 
Agreement respecting sales of Registrable Securities; and, 
provided, further, that the indemnity with respect to any 
preliminary prospectus shall not apply to the extent that any such 
claim, loss, damage or liability results from the fact that a 
current copy of the prospectus was not sent or given to the person 
asserting any such claims, losses, damages or liabilities at or 
prior to the written confirmation of the sale of the Registrable 
Securities confirmed to such person if such current copy of the 
prospectus would have cured the defect giving rise to such claim, 
loss, damage or liability.

	(ii)  Each Holder will severally, if Registrable Securities 
held by such Holder are included in the securities as to which 
such registration, qualification or compliance is being effected, 
indemnify the Company, each of its directors, officers, employees, 
partners, legal counsel and accountants, each underwriter, if any, 
and each person who controls the Company or such underwriter 
within the meaning of Section 15 of the Securities Act, against 
all claims, losses, damages and liabilities (or actions in respect 
thereof), including any of the foregoing incurred in settlement of 
any litigation, commenced or threatened, arising out of or based 
on any untrue statement (or alleged untrue statement) of a 
material fact contained in any registration statement, prospectus, 
offering circular or other document, or any amendment or 
supplement thereof, incident to any such registration, 
qualification or compliance, or based on any omission (or alleged 
omission) to state therein a material fact required to be stated 
therein or necessary to make the statements therein not 
misleading, or any failure by a Holder to comply with the 
covenants or agreements contained in this Agreement respecting the 
Registrable Securities and will reimburse the Company, such 
directors, officers, employees, partners, legal counsel and 
accountants for reasonable legal and any other expenses reasonably 
incurred in connection with investigating, preparing or defending 
any such claim, loss, damage, liability or action as incurred, in 
each case to the extent, but only to the extent, that such untrue 
statement or omission or allegation thereof is made in reliance 
upon and in conformity with written information furnished to the 
Company by an instrument duly executed by or on behalf of the 
Holder and stated to be specifically for use in preparation of 
such registration statement, prospectus, offering circular or 
other document; provided that the indemnity with respect to any 
preliminary prospectus shall not apply to the extent that such 
claim, loss, damage or liability results from the fact that a 
current copy of the prospectus was not sent or given to the person 
asserting any such claim, loss, damage or liability at or prior to 
the written confirmation of the sale of the Registrable Securities 
confirmed to such person if such current copy of the prospectus 
would have cured the defect giving rise to such loss, claim, 
damage or liability.  Notwithstanding the foregoing, in no event 
shall a Holder be liable for any such claims, losses, damages or 
liabilities in excess of the proceeds received by such Holder in 
the offering, except in the event of fraud by such Holder.  

	(iii)  Each party entitled to indemnification under this 
Section 8.1(e) (the Indemnified Party) shall give notice to the 
party required to provide indemnification (the Indemnifying Party) 
promptly after such Indemnified Party has actual knowledge of any 
claim as to which indemnity may be sought, and shall permit the 
Indemnifying Party to assume the defense of any such claim or any 
litigation resulting therefrom, provided that counsel for the 
Indemnifying Party, who shall conduct the defense of such claim or 
litigation, shall be approved by the Indemnified Party (whose 
approval shall not unreasonably be withheld), and the Indemnified 
Party may participate in such defense at such party's expense, and 
provided further that the failure of any Indemnified Party to give 
notice as provided herein shall not relieve the Indemnifying Party 
of its obligations under this Agreement, unless such failure is 
prejudicial to the Indemnifying Party in defending such claim or 
litigation.  An Indemnifying Party shall not be liable for any 
settlement of an action or claim effected without its written 
consent (which consent will not be unreasonably withheld).

	(iv)  If the indemnification provided for in this Section 
8.1(e) is held by a court of competent jurisdiction to be 
unavailable to an Indemnified Party with respect to any loss, 
liability, claim, damage or expense referred to therein, then the 
Indemnifying Party, in lieu of indemnifying such Indemnified Party 
thereunder, shall contribute to the amount paid or payable by such 
Indemnified Party as a result of such loss, liability, claim, 
damage or expense in such proportion as is appropriate to reflect 
the relative fault of the Indemnifying Party on the one hand and 
of the Indemnified Party on the other in connection with the 
statements or omissions which resulted in such loss, liability, 
claim, damage or expense as well as any other relevant equitable 
considerations.  The relative fault of the Indemnifying Party and 
of the Indemnified Party shall be determined by reference to, 
among other things, whether the untrue or alleged untrue statement 
of a material fact or the omission to state a material fact 
relates to information supplied by the Indemnifying Party or by 
the Indemnified Party and the parties' relative intent, knowledge, 
access to information and opportunity to correct or prevent such 
statement or omission.

(f)  Covenants of Holders.

	(i)  Each Holder agrees that, upon receipt of any notice from 
the Company of the happening of any event requiring the 
preparation of a supplement or amendment to a prospectus relating 
to Registrable Securities so that, as thereafter delivered to the 
Holders, such prospectus will not contain an untrue statement of a 
material fact or omit to state any material fact required to be 
stated therein or necessary to make the statements therein not 
misleading, each Holder will forthwith discontinue disposition of 
Registrable Securities pursuant to the registration statement 
contemplated by Section 8.1(a) until its receipt of copies of the 
supplemented or amended prospectus from the Company and, if so 
directed by the Company, each Holder shall deliver to the Company 
all copies, other than permanent file copies then in such Holder's 
possession, of the prospectus covering such Registrable Securities 
current at the time of receipt of such notice.

	(ii)  Each Holder agrees to suspend, upon request of the 
Company, any disposition of Registrable Securities pursuant to the 
registration statement and prospectus contemplated by 
Section 8.1(a) during (A) any period not to exceed two 30-day 
periods within any one 12-month period the Company requires in 
connection with a primary underwritten offering of equity 
securities and (B) any period, not to exceed one 30-day period per 
circumstance or development, when the Company determines in good 
faith that offers and sales pursuant thereto should not be made by 
reason of the presence of material, undisclosed circumstances or 
developments with respect to which the disclosure that would be 
required in such a prospectus is premature, would have an adverse 
effect on the Company or is otherwise inadvisable.

	(iii)  Each Holder agrees to notify the Company, at any time 
when a prospectus relating to the registration statement 
contemplated by Section 8.1(a) is required to be delivered by it 
under the Securities Act, of the occurrence of any event relating 
to the Holder which requires the preparation of a supplement or 
amendment to such prospectus so that, as thereafter delivered to 
the purchasers of Registrable Securities, such prospectus will not 
contain an untrue statement of a material fact or omit to state 
any material fact required to be stated therein or necessary to 
make the statements therein not misleading relating to the Holder, 
and each Holder shall promptly make available to the Company the 
information to enable the Company to prepare any such supplement 
or amendment.  Each Holder also agrees that, upon delivery of any 
notice by it to the Company of the happening of any event of the 
kind described in the next preceding sentence of this subsection, 
the Holder will forthwith discontinue disposition of Registrable 
Securities pursuant to such registration statement until its 
receipt of the copies of the supplemental or amended prospectus 
contemplated by this subsection, which the Company shall promptly 
make available to each Holder and, if so directed by the Company, 
each Holder shall deliver to the Company all copies, other than 
permanent file copies then in such Holder's possession, of the 
prospectus covering such Registrable Securities current at the 
time of receipt of such notice.

	(iv)  Each Holder shall furnish to the Company such 
information regarding such Holder and the distribution proposed by 
such Holder as the Company may request in writing or as shall be 
required in connection with any registration, qualification or 
compliance referred to in this Section 8.1.

	(v)  Each Holder hereby covenants with the Company (1) not to 
make any sale of the Registrable Securities without effectively 
causing the prospectus delivery requirements under the Securities 
Act to be satisfied, and (2) if such Registrable Securities are to 
be sold by any method or in any transaction other than on the AMEX 
(or other national securities exchange), in the over-the-counter 
market, on the NASDAQ National Market, in privately negotiated 
transactions, or in a combination of such methods, to notify the 
Company at least five business days prior to the date on which the 
Holder first offers to sell any such Shares.

	(vi)  Each Holder acknowledges and agrees that the 
Registrable Securities sold pursuant to the registration statement 
described in this Section are not transferable on the books of the 
Company unless the stock certificate submitted to the transfer 
agent evidencing such Shares is accompanied by a certificate 
reasonably satisfactory to the Company to the effect that (A) the 
Registrable Securities have been sold in accordance with such 
registration statement and (B) the requirement of delivering a 
current prospectus has been satisfied.

	(vii)  Each Holder agrees that it will not effect any 
disposition of the Registrable Securities that would constitute a 
sale within the meaning of the Securities Act except as 
contemplated in the registration statement referred to in this 
Section 8.1.  Each Holder agrees not to take any action with 
respect to any distribution deemed to be made pursuant to such 
registration statement that constitutes a violation of 
Rule 10(b)-6 under the Exchange Act or any other applicable rule, 
regulation or law.

(g)  Rule 144 Reporting.  With a view to making available to the 
Holders the benefits of certain rules and regulations of the SEC 
which at any time permit the sale of the Registrable Securities to 
the public without registration, the Company agrees to use its 
reasonable best efforts to:

	(i)  make and keep public information available, as those 
terms are understood and defined in Rule 144 under the Securities 
Act, at all times;

	(ii)  file with the SEC in a timely manner all reports and 
other documents required of the Company under the Exchange Act; 
and 

	(iii)  so long as a Holder owns any unregistered Registrable 
Securities, furnish to such Holder upon any reasonable request a 
written statement by the Company as to its compliance with 
Rule 144 under the Securities Act, and of the Exchange Act, a copy 
of the most recent annual or quarterly report of the Company, and 
such other reports and documents of the Company as such Holder may 
reasonably request in availing itself of any rule or regulation of 
the SEC allowing a Holder to sell any such securities without 
registration.

(h)  Transfer of Registration Rights.  The rights to cause the 
Company to include Registrable Securities in a Registration 
Statement granted to the Holders by the Company under 
Section 8.1(a) may be assigned in full by a Holder to an Affiliate 
of such Holder; provided that: (i) such transfer may otherwise be 
effected in accordance with applicable securities laws; (ii) such 
Holder gives prior written notice to the Company; and (iii) such 
transferee agrees to comply with the terms and provisions of this 
Agreement, including, without limitation, the restrictions in 
Section 4.6 and such transfer is otherwise in compliance with this 
Agreement.  Except as specifically permitted by this 
paragraph (h), the rights of a Holder with respect to Registrable 
Securities as set out herein shall not be transferable to any 
other Person, and any attempted transfer shall cause all rights of 
such Holder therein to be forfeited.  

(i)  Waivers and Amendments.  With the written consent of the 
Company and the Holders holding at least a majority of the 
outstanding Registrable Securities, any provision of this 
Section 8.1 may be waived (either generally or in a particular 
instance, either retroactively or prospectively, and either for a 
specified period of time or indefinitely) or amended.  Upon the 
effectuation of each such waiver or amendment, the Company shall 
promptly give written notice thereof to the Holders, if any, who 
have not previously received notice thereof or consented thereto 
in writing.

8.2  Disposition.  The Purchaser has not and will not make any 
offer, sale or other transfer of the Notes or the Conversion 
Shares by any means which would not comply with applicable law or 
this Agreement or which would otherwise impose upon the Company 
any obligation to satisfy any public filing or registration 
requirement.  The Purchaser understands and agrees that any 
disposition of the Notes or the Conversion Shares in violation of 
this Agreement shall be null and void, and that no transfer of the 
Notes or the Conversion Shares shall be made by the Company or the 
transfer agent for the Notes or the Conversion Shares upon the 
Company's stock transfer books or records unless and until there 
has been compliance with the terms of this Agreement, the 
Securities Act, any applicable state and foreign securities law 
and any other laws.  It will not sell or transfer the Notes or the 
Conversion Shares unless

	(a)  (in the case of the Conversion Shares) there is then in 
effect a registration statement under the Securities Act covering 
such proposed disposition and such disposition is made in 
accordance with such Registration Statement; or

	(b) it shall have notified the Company of the proposed 
disposition and shall have furnished the Company with a detailed 
statement of the circumstances surrounding the proposed 
disposition, and unless waived by the Company it shall have 
furnished the Company with an opinion of counsel, reasonably 
satisfactory to the Company that such disposition is exempt from 
registration of such shares under the Securities Act or any 
applicable state, foreign or other securities laws.  

The Purchaser will not transfer the Conversion Shares or Notes 
(other than in the case of the Conversion Shares  pursuant to the 
Registration Statement contemplated by Section 8 hereof, or in a 
transaction that complies with Rule 144), unless the transferee 
makes the representations and warranties to the Company contained 
in this Agreement and agrees to be bound by the restrictions on 
transfer (including the registration provisions) contained herein 
to the same extent as if it were the original Purchaser.  Without 
limiting the generality of any provision contained herein, at any 
time it owns Notes or Conversion Shares the Purchaser and each 
transferee must and does agree that it and its respective 
Affiliates will comply with all provisions of Section 4.6.

8.3  AMEX Approval for Listing. The Company agrees to use its 
reasonable best efforts to obtain approval for listing of the 
Conversion Shares and the Warrant Shares on the AMEX as promptly 
as practicable.  

SECTION 9
Redemption of Notes

9.1  Right of Redemption.  The Notes may be redeemed at the 
election of the Company, as a whole or from time to time in part, 
any time on or after the issue date of the Notes at a price equal 
to 100% of the principal amount of the Notes to be redeemed (the 
Redemption Price), together with accrued and unpaid interest to 
the date fixed by the Company for such redemption (the Redemption 
Date).

9.2  Applicability of Section.  Redemption of Notes at the 
election of the Company, as permitted by any provision of this 
Agreement, shall be made in accordance with such provision and 
this Section 9.

9.3  Election to Redeem.  The election of the Company to redeem 
any Notes pursuant to Section 9.1 shall be evidenced by a 
resolution duly adopted by the board of directors of the Company. 

9.4  Selection by the Company of Notes to Be Redeemed.  If less 
than all the Notes are to be redeemed pursuant to Section 9.1, the 
particular Notes to be redeemed shall be selected by the Company 
from the Notes then Outstanding not previously called for 
redemption by the Company in its sole discretion in portions equal 
to $1,000 or any integral multiple thereof of the principal amount 
of Notes of a denomination larger than $1,000.

If any Note selected for partial redemption is converted in part 
before termination of the conversion right with respect to the 
portion of the Note so selected, the converted portion of such 
Note shall be deemed (so far as may be) to be the portion selected 
for redemption.  Notes which have been converted during a 
selection of Notes to be redeemed shall be deemed to be 
outstanding for the purpose of such selection.

For all purposes of this Agreement, unless the context otherwise 
requires, all provisions relating to the redemption of Notes shall 
relate, in the case of any Notes redeemed or to be redeemed only 
in part, to the portion of the principal amount of such Notes 
which has been or is to be redeemed.

9.5  Notice of Redemption.  Notice of redemption shall be given by 
the Company by first-class mail, postage prepaid, mailed not less 
than 20 nor more than 60 days prior to the Redemption Date, to 
each Holder of Notes to be redeemed, at the address specified in 
Section 12.5.

All notices of redemption shall state:  

(1)  the Redemption Date,

(2)  the Redemption Price, and the amount of accrued but unpaid 
interest as of the Redemption Date,

(3)  if less than all the Outstanding Notes are to be redeemed, 
the identification (and, in the case of partial redemption, the 
principal amounts) of the particular Notes to be redeemed),

(4)  that on the Redemption Date the Redemption Price will become 
due and payable upon each such Note to be redeemed and that 
interest thereof will cease to accrue on and after said date,

(5) the  conversion price, the date on which the right to convert 
the principal of the Notes to be redeemed will terminate and the 
place or places where such Notes may be surrendered for 
conversion, and

(6)  the place or places in New York City  where such Notes are to 
be surrendered for payment of the Redemption Price.

9.6  Notes Payable on Redemption Date.  Notice of redemption 
having been given as aforesaid, the Notes so to be redeemed shall, 
on the Redemption Date, become due and payable at the Redemption 
Price therein specified, and from and after such date (unless the 
Company shall default in the payment of the Redemption Price and 
accrued interest) such Notes shall cease to bear interest.  Upon 
surrender of any such Note for redemption in accordance with said 
notice, such Note shall be paid by the Company at the Redemption 
Price, together with accrued interest to the Redemption Date.

If any Note called for redemption shall not be so paid upon 
surrender thereof for redemption, the principal shall, until paid, 
bear interest from the Redemption Date at the rate borne by the 
Note.

9.7  Notes Redeemed in Part.  Any Note which is to be redeemed 
only in part shall be surrendered at the office of the Company's 
agent in New York City (with due endorsement by, or a written 
instrument of transfer in form satisfactory to the Company duly 
executed by the Holder thereof or his attorney duly authorized in 
writing), and the Company shall execute, authenticate and deliver 
to the Holder of such Note without service charge, a new Note or 
Notes, of any authorized denomination as requested by such Holder, 
in aggregate principal amount equal to and in exchange for the 
unredeemed portion of the principal of the Note so surrendered.

SECTION 10
Conversion of Notes

10.1  Right of Conversion.  The Holder of any Note or Notes shall 
have the right at any time after the occurrence of both (i) the 
Closing and (ii) the AMEX's approval of the listing of the 
Conversion Shares, up to the close of business on the fifth 
Business Day prior to the Stated Maturity of the Note, at the 
Holder's option, to convert, subject to the terms and provisions 
of this Section 10, the principal of any such Note or Notes (or 
any portion of the principal thereof which is $1,000 or an 
integral multiple of $1,000) and the related interest (as 
specified in Section 10.3)  into fully paid and nonassessable 
shares of Common Stock of the Company, at the conversion price and 
rate and upon the other terms set forth in this Section 10 (except 
that with respect to any Note or Notes or any such portion, which 
shall be called for redemption, such right shall terminate, except 
as provided in the last paragraph of Section 10.2 at the close of 
business on the fifth business day prior to the Redemption Date 
for such Note or Notes or portion).

The price at which shares of Common Stock shall be delivered upon 
conversion (herein called the conversion price) shall initially be 
at the conversion price set forth in the Note. The conversion 
price shall be adjusted in certain instances as provided in this 
paragraph and in Section 10.5 and all references to conversion 
price shall mean the conversion price as most recently adjusted.  
Subject to the adjustments pursuant to the provisions of Section 
10.5, the conversion price that is in effect immediately prior to 
the date that is the twentieth Business Day prior to the maturity 
date of the Notes (the Reset Date) shall be adjusted and reset 
effective as of such Reset Date so that the same shall equal the 
greater of (i) the average closing price of the Common Stock for 
the 10 consecutive trading days immediately preceding the Reset 
Date and (ii) 50% of the conversion price in effect on the trading 
day immediately prior to the Reset Date, provided, however, that 
such adjustment shall be made only if the conversion price as so 
adjusted would be lower than the conversion price that is in 
effect immediately prior to such adjustment.  The Company shall 
promptly give notice of such a reset of the conversion price in 
writing to the Holder of each Note, which notice shall specify the 
conversion price as so adjusted.    

In order to exercise the conversion privilege, the Holder of any 
Note to be converted shall surrender the Note or Notes, the 
principal and the related interest (as specified in Section 10.3) 
of which is so to be converted, to the Company at any time during 
usual business hours at the office of the conversion agent for the 
Company in New York City, accompanied by written notice in the 
form attached hereto as Exhibit F that the Holder elects to 
convert such Note or Notes or any portion thereof and specifying 
the name or names with address (which, if name and address is 
other than for the Holder, must also comply with any requirements 
for transfer contained in this Agreement) in which a certificate 
or certificates for Common Stock are to be issued and by a written 
instrument or instruments or transfer in form satisfactory to the 
Company, duly executed by the Holder or his attorney, duly 
authorized in writing and transfer tax stamps or funds therefor, 
if required pursuant to Section 10.9.  For convenience, the 
conversion of all or a portion, as the case may be, of the 
principal of any Note into the Common Stock of  the Company is 
hereafter sometimes referred to as the conversion of such Note.  
All Notes surrendered for conversion shall be forwarded by the 
conversion agent to the Company and shall be delivered to the 
Company for cancellation and canceled by it; and, subject to the 
next succeeding sentence, no Notes shall be issued in lieu 
thereof. In the case of any Note which is converted in part only, 
upon such conversion the Company shall execute, authenticate and 
cause its conversion agent to deliver to the Holder thereof, at 
the expense of the Company, a new Note or Notes of authorized 
denominations in an aggregate principal amount equal to the 
unconverted portion of the principal amount of such Note.

10.2  Issuance of Common Stock; Time of Conversion.  As promptly 
as practicable after the surrender, as herein provided, of any 
Note or Notes for conversion, the Company shall deliver or cause 
to be delivered at the office of the conversion agent for the 
Company in New York City to or upon the written order of the 
Holder of the Note or Notes so surrendered a certificate or 
certificates representing the number of fully paid and 
nonassessable shares of Common Stock of the Company into which 
such Note or Notes (or portion thereof) may be converted in 
accordance with the provisions of this Section 10. Subject to the 
following provisions of this paragraph and of Section 10.5, such 
conversion shall be deemed to have been made immediately prior to 
the close of business on the date that such Note or Notes shall 
have been surrendered in satisfactory form for conversion, so that 
the rights of the Holder as a Holder shall cease with respect to 
such Note or Notes (or the portion thereof being converted) at 
such time, and the Person or Persons entitled to receive the 
shares of Common Stock deliverable upon conversion of such Note or 
Notes shall be treated for all purposes as having become the 
record holder or holders of such shares of Common Stock at such 
time, and such conversion shall be at the conversion price in 
effect at such time; provided, however, that no such surrender on 
any date when the stock transfer books of the Company shall be 
closed shall be effective to constitute the Person or Persons 
entitled to receive the shares of Common Stock deliverable upon 
such conversion as the record holder or holders of such shares of 
Common Stock on such date, but such surrender shall be effective 
to constitute the Persons or Persons entitled to receive such 
shares of Common Stock as the record holder or holders thereof for 
all purposes immediately prior to the close of business on the 
next succeeding day on which such stock transfer books are open, 
and such conversion shall be deemed to have been made at, and 
shall be made at the conversion price in effect at, such time on 
such next succeeding day.

If the last day for the exercise of the conversion right shall not 
be a Business Day, then such conversion right may be exercised on 
the next succeeding Business Day.

10.3  No Conversion in Respect of Interest.  For any Note or 
portion of a Note that is converted, the accrued interest with 
respect to the principal amount of such Note must also be 
converted simultaneously with such conversion of principal.  No 
other payment or adjustment shall be made upon any conversion on 
account of any interest accrued on the Notes surrendered for 
conversion.  In the case of any Note that is converted, interest 
whose Stated Maturity is after the date of conversion of such Note 
shall not be payable.  

10.4  Reservation of Shares; Par Value of Common Stock.  There has 
been reserved, and the Company shall at all times keep reserved so 
long as the Notes remain Outstanding, out of its authorized Common 
Stock, such number of shares of Common Stock as shall be subject 
to issuance upon conversion of the Notes.  Every transfer agent 
for the Common Stock and other securities of the Company issuable 
upon the conversion of the Notes will be irrevocably authorized 
and directed at all times to reserve such number of authorized 
shares and other securities as shall be requisite for such 
purpose.  The Company will keep a copy of this Agreement on file 
with every transfer agent for the Common Stock and other 
securities of the Company issuable upon the conversion of the 
Notes.  The Company will supply every such transfer agent with 
duly executed stock and other certificates, as appropriate, for 
such purpose and will provide or otherwise make available any cash 
which may be payable as provided in Section 10.7 hereof.  On or 
before taking any action that would cause an adjustment pursuant 
to the terms of the Notes resulting in an increase in the number 
of shares of Common Stock deliverable upon such conversion above 
the number thereof previously authorized, reserved and available 
therefor, the Company shall take all such action so required for 
compliance with this Section.

Before taking any action which would cause an adjustment reducing 
the conversion price below the then par value per share of the 
shares of Common Stock issuable upon conversion of the Notes, the 
Company will take any corporate action which may, in the opinion 
of its counsel, be necessary in order that the Company may validly 
and legally issue fully paid and nonassessable shares of Common 
Stock at such conversion price as so adjusted.

10.5  Adjustments of Conversion Price.  The conversion price shall 
be subject to adjustment from time to time as follows:

	(a)  In case the Company shall (i) pay a dividend in Common 
Stock or make a distribution in Common Stock, (ii) subdivide its 
outstanding Common Stock, (iii) combine its outstanding Common 
Stock into a smaller number of shares of Common Stock or (iv) 
issue by reclassification of its Common Stock other securities of 
the Company, the conversion privilege and the conversion price in 
effect immediately prior thereto shall be adjusted so that the 
Holder of any Notes thereafter surrendered for conversion shall be 
entitled to receive the kind and number of shares or other 
securities of the Company which it would have owned or would have 
been entitled to receive immediately after the happening of any of 
the events described above had the Notes been converted 
immediately prior to the happening of such event or any record 
date with respect thereto. Any adjustment made pursuant to this 
Section 10.5(a) shall become effective immediately after the 
effective date of such event retroactive to the record date, if 
any, for such event.

	(b)  In case the Company shall issue rights, options, 
warrants or convertible securities to all or substantially all 
holders of its Common Stock, without any charge to such holders, 
entitling them to subscribe for or purchase Common Stock at a 
price per share which is lower at the record date mentioned below 
than the then Fair Value (as defined in Section 10.7), the 
conversion price shall be adjusted so that the same shall equal 
the price determined by multiplying the conversion price in effect 
immediately prior to the date of issuance of such rights, options, 
warrants or securities by a fraction, of which the numerator shall 
be the number of shares of Common Stock outstanding immediately 
prior to the issuance of such rights, options, warrants or 
convertible securities  plus the number of shares which the 
aggregate offering price of the total number of shares offered 
would purchase at such Fair Value, and of which the denominator 
shall be the number of shares of Common Stock outstanding 
immediately prior to the issuance of such rights, options, 
warrants or convertible securities plus the number of additional 
shares of Common Stock offered for subscription or purchase. Such 
adjustment shall be made whenever such rights, options, warrants 
or convertible securities are issued, and shall become effective 
immediately and retroactive to the record date for the 
determination of shareholders entitled to receive such rights, 
options, warrants or convertible securities.

	(c)  In case the Company shall distribute to all or 
substantially all holders of its Common Stock evidences of its 
indebtedness or assets (excluding cash dividends or distributions 
out of earnings) or rights, options, warrants or convertible 
securities containing the right to subscribe for or purchase 
Common Stock (excluding those referred to in Section 10.5(b) 
above), then in each case the conversion price shall be adjusted 
so that the same shall equal the price determined by multiplying 
the conversion price in effect immediately prior to such 
distribution by a fraction, of which the numerator shall be the 
then Fair Value per share of Common Stock on the record date for 
such distribution minus the then Fair Value of the portion of the 
assets or evidences of indebtedness so distributed or of such 
subscription rights, options, warrants or convertible securities 
applicable to one share of Common Stock, and of which the 
denominator shall be the then Fair Value per share of Common Stock 
on the record date for such distribution.  Such adjustment shall 
be made whenever any such distribution is made and shall become 
effective on the date of distribution retroactive to the record 
date for the determination of shareholders entitled to receive 
such distribution.

	(d)  No adjustment in the conversion price shall be required 
unless such adjustment would require an increase or decrease of at 
least three percent in such price; provided, however, that any 
adjustments which by reason of this Section 10.5(d) are not 
required to be made immediately shall be carried forward and taken 
into account in any subsequent adjustment.

	(e)  Whenever the conversion price  is adjusted as herein 
provided, the Company shall cause to be promptly mailed to the 
Holders of the Notes by first class mail, postage prepaid, notice 
of such adjustment and a certificate of the chief financial 
officer of the Company setting forth the adjusted conversion 
price, a brief statement of the facts requiring such adjustment 
and the computation by which such adjustment was made.

	(f)  For the purpose of this Section 10.5, the term Common 
Stock shall mean (i) the class of stock designated as the Common 
Stock of the Company at the date of this Agreement or (ii) any 
other class of stock resulting from successive change or 
reclassifications of such Common Stock consisting solely of 
changes in par value, or from par value to no par value, or from 
no par value to par value.  In the event that at any time, as a 
result of an adjustment made pursuant to this Section 10, the 
Holder of any Notes shall become entitled to convert such Notes 
into any securities of the Company other than Common Stock, (i) if 
the Holder of any Note's right to convert is on any other basis 
than that available to all holders of the Company's Common Stock, 
the Company shall obtain an opinion of an independent investment 
banking firm valuing such other securities and (ii) thereafter the 
number of such other securities so purchasable upon conversion of 
the Notes shall be subject to adjustment from time to time in a 
manner and on terms as nearly equivalent as practicable to the 
provisions with respect to the shares contained in this Section 
10.5.

	(g)  Upon the expiration of any rights, options, warrants or 
conversion privileges, if such shall not have been exercised, the 
conversion price, to the extent the Notes have not then been 
converted, shall, upon such expiration, be readjusted and shall 
thereafter be such as it would have been had it been originally 
adjusted (or had the original adjustment not been required, as the 
case may be) on the basis of (i) the fact that Common Stock, if 
any, actually issued or sold upon the exercise of such rights, 
options, warrants or conversion privileges, and (ii) the fact that 
such shares of Common Stock, if any, were issued or sold for the 
consideration actually received by the Company upon such exercise 
plus the consideration, if any, actually received by the Company 
for the issuance, sale or grant of all such rights, options, 
warrants or conversion privileges whether or not exercised; 
provided, however, that no such readjustment shall have the effect 
of increasing the conversion price by an amount in excess of the 
amount of the adjustment initially made in respect of the 
issuance, sale or grant of such rights, options, warrants or 
conversion privileges.

10.6  No Adjustment for Certain Matters.  During the term of the 
Notes or upon the conversion of the Notes, no adjustment shall be 
made (i) except as provided in Section 10.5 in respect of any 
dividends or distributions out of earnings or (ii) in respect of 
the consummation of any action described in Section 10.8(b).  
Without limiting the generality of the foregoing, the Company 
shall have no obligation to cause any purchaser or successor by 
merger, sale of assets or similar business combination to assume 
the obligations under this Agreement.

10.7  Fractional Interests; Fair Value.  The Company shall not be 
required to issue fractional shares on conversion of the Notes.  
If any fraction of a share would, except for the provisions of 
this Section 10.7, be issuable on the conversion of the Notes (or 
specified portion thereof), the Company shall pay an amount in 
cash equal to the then Fair Value of the Common Stock multiplied 
by such fraction.  As used herein, the term Fair Value of the 
Common Stock or other securities or other property shall mean the 
fair value as determined in good faith by the Company's Board of 
Directors, which determination shall be binding upon the Holders 
of the Notes; provided, however, that Fair Value of the Common 
Stock for any day shall mean the last sales price, regular way, on 
the day in question or, in case no such sale takes place on such 
day, the average of the closing bid and asked prices, regular way, 
on such day, in either case as reported in the principal 
transaction reporting system with respect to securities listed or 
admitted to trading on the AMEX, or, if such security is not 
listed or admitted to trading on the AMEX, on the principal 
national securities exchange on which such security is listed or 
admitted to trading, or, if such security is not listed or 
admitted to trading on any national securities exchange but sales 
price information is reported for such security, as reported by 
NASDAQ or such other self-regulatory organization or registered 
securities information processor (as such terms are used under the 
Securities Exchange Act of 1934, as amended) that then reports 
information concerning such security, or, if sales price 
information is not so reported, the average of the high bid and 
low asked prices in the over-the-counter market on such day, as 
reported by NASDAQ or such other entity, or, if on such day such 
security is not quoted by any such entity, the average of the 
closing bid and asked prices as furnished by a professional market 
maker making a market in such security selected by the Board of 
Directors of the Company.  If on such day no market maker is 
making a market in such security, the fair value of such security 
on such day as determined in good faith by the Board of Directors 
of the Company shall be used.

10.8  No Right as Stockholder; Notices to Noteholder.  Nothing 
contained in this Agreement or in the Note shall be construed as 
conferring upon the Holder of any Note or Notes any rights as a 
stockholder of the Company, including the right to vote, receive 
dividends, consent or receive notices as a stockholder in respect 
of any meeting of stockholders for the election of directors of 
the Company or any other matter.  If, however, at any time prior 
to the expiration of the Notes and prior to their conversion, any 
one or more of the following events shall occur:

	(a)  any action which would require  an adjustment pursuant 
to Section 10.5 (except Section 10.5(f)); or

	(b)  a dissolution, liquidation or winding up of the Company 
or a consolidation, merger or similar business combination or sale 
of its property, assets and business as an entirety or 
substantially as an entirety shall be proposed;

then the Company shall give notice in writing of such event to the 
Holder of any Note or Notes, as provided in Section 10.8 hereof, 
promptly prior to the date fixed as a record date or the date of 
closing the transfer books for the determination of the 
stockholders entitled to any relevant dividend, distribution, 
subscription rights or other rights, or for the determination of 
stockholders entitled to vote on such proposed dissolution, 
liquidation or winding up.  Such notice shall specify such record 
date or the date of closing the transfer books, as the case may 
be.  Failure to mail or receive such notice or any defect therein 
shall not affect the validity of any action taken with respect 
thereto.

10.9  Taxes and Charges.  The issuance of certificates for shares 
of Common Stock upon the conversion of Notes shall be made without 
charge to the converting Holder of Notes for such certificates or 
for any tax in respect of the issuance of such certificates or the 
securities represented thereby, and such certificates shall be 
issued in the respective names of, or in such names as may be 
directed by, the Holders of the Notes converted; provided, 
however, that the Company shall not be required to pay any tax 
which may be payable in respect of any transfer involved in the 
issuance and delivery of any such certificate in a name other than 
that of the Holder of the Note converted, and the Company shall 
not be required to issue or deliver such certificates unless or 
until the Person or Persons requesting the issuance thereof shall 
have paid to the Company the amount of such tax or shall have 
established to the satisfaction of the Company that such tax has 
been paid.

SECTION 11
Payments of Notes and Related Matters

11.1  Note Payments.  So long as the Purchaser holds any Note, the 
Company will make payments of principal of, interest on such Note, 
which comply with the terms of this Agreement in New York City, by 
wire transfer of immediately available funds for credit (not later 
than 12:00 noon, New York City time, on the date due) to such 
Purchaser's account or accounts in New York City as such Purchaser 
may designate in writing, notwithstanding any contrary provision 
herein or in any Note with respect to the place of payment.  Each 
Purchaser agrees that, before disposing of any Note, it will make 
a notation thereon (or on a schedule attached thereto) of all 
payments previously made thereon.  Notwithstanding any other 
provision of this Agreement, all payments of any obligation of the 
Company hereunder must be made by the Company in the State of New 
York.

11.2  Form, Registration,Transfer and Exchange of Notes; Lost 
Notes.  The Notes are issuable as registered notes without coupons 
in denominations of at least $100,000, except as may be necessary 
to effect any principal amount not evenly divisible by $100,000.  
The Company shall keep at its principal office a register (the 
Note Register) in which the Company shall provide for the 
registration of Notes and of transfers of Notes.  Upon surrender 
for registration of transfer of any Note at the principal office 
of the Company, the Company shall, at its expense, promptly 
execute and deliver one or more new Notes of like tenor and of a 
like aggregate principal amount, registered in the name of such 
transferee or transferees.  In the case that any Note is 
surrendered for transfer, the new Note issued to the transferee 
must include a legend relating to original issue discount to the 
extent required by applicable law.  At the option of the Holder of 
any Note, such Note may be exchanged for other Notes of like tenor 
and of any authorized denominations, of a like aggregate principal 
amount, upon surrender of the Note to be exchanged at the 
principal office of the Company.  Whenever any Notes are so 
surrendered for exchange, the Company shall, at its expense, 
execute and deliver the Notes which the Holder making the exchange 
is entitled to receive promptly after the request by the Holder of 
such Note.  Every Note surrendered for registration of transfer or 
exchange shall be duly endorsed, or be accompanied by a written 
instrument to transfer duly executed, by the Holder of such Note 
or such Holder's attorney duly authorized in writing together with 
any opinion or other documentation required under this Agreement.  
Any Note or Notes issued in exchange for any Note or upon transfer 
thereof shall carry the rights to unpaid interest and interest to 
accrue which were carried by the Note so exchanged or transferred, 
so that neither gain nor loss of interest shall result from any 
such transfer or exchange.  Upon receipt of written notice from 
the Holder of any Note of the loss, theft, destruction or 
mutilation of such Note and, in the case of any such loss, theft 
or destruction, upon receipt of either (in the sole discretion of 
the Company) such Holder's letter agreement in form acceptable to 
the Company or an insurance bond indemnifying the Company against 
loss in respect thereto, or in the case of any such mutilation 
upon surrender and cancellation of such Note, the Company will 
promptly make and deliver a new Note, of like tenor, in lieu of 
the lost, stolen, destroyed or mutilated Note.

11.3  Persons Deemed Owners.  Prior to due presentment for 
registration of transfer, the Company may treat the Person in 
whose name any Note is registered as the owner and Holder of such 
Note for the purpose of receiving payment of principal of and 
interest on such Note and for all other purposes whatsoever, 
whether or not such Note shall be overdue, and the Company shall 
not be affected by notice to the contrary.  

11.4  Payments Due on Non-Business Days.   Anything in this 
Agreement or the Notes to the contrary notwithstanding, any 
payment of principal of or interest on any Note that is due on a 
date other than a Business Day shall be made on the next 
succeeding Business Day.  If the date for any payment is extended 
to the next succeeding Business Day by reason of the preceding 
sentence, the period of such extension shall be included in the 
computation of the interest payable on such Business Day.

11.5  Limitation on Interest.  Regardless of any provision 
contained herein, or in any other document executed in connection 
herewith, the Holder of any Note or Notes shall never be entitled 
to receive, collect or apply, as interest hereon, any unearned 
interest or any amount in excess of the maximum non-usurious 
contract rate of interest allowed from time to time by applicable 
law (the Highest Lawful Rate), and in the event such Holder ever 
receives, collects or applies, as interest, any unearned interest 
or any such excess, such amount shall be deemed a partial 
prepayment of principal, and, if the principal hereof is paid in 
full, any remaining excess shall forthwith be refunded to the 
Company.  In determining whether or not the interest paid or 
payable, under any specific contingency, exceeds the Highest 
Lawful Rate, the Company and such Holder shall, to the maximum 
extent permitted by law, (a) characterize any non principal 
payment as an expense or fee rather than as interest, (b) exclude 
voluntary prepayment and the effects thereof and (c) amortize, 
prorate, allocate and spread, in equal parts, the total amount of 
interest throughout the entire contemplated term of the Note so 
that the interest rate is uniform throughout the entire term 
thereof.

SECTION 12
Miscellaneous

12.1  Termination of Agreement.  Prior to the Closing, the Company 
may terminate its obligation to perform or observe any of its 
covenants and agreements hereunder to any Purchaser if such 
Purchaser violates in a material respect any of the material 
covenants or agreements of the Purchaser under this Agreement, and 
a Purchaser may terminate its obligations to perform or observe 
any of its covenants and agreements hereunder if the Company 
violates or fails to perform in any material respect any of the 
material covenants or agreements of the Company under this 
Agreement to such Purchaser; provided, however, that neither the 
Company nor the Purchaser, as the case may be, may terminate any 
of its obligations under this Agreement pursuant to this sentence 
unless it shall have delivered written notice of such default to 
the other party and such default shall not have been cured within 
30 days after the delivery of such notice.

12.2  Governing Law.  THIS AGREEMENT SHALL BE GOVERNED IN ALL 
RESPECTS BY THE LAWS OF THE STATE OF NEW YORK AS APPLIED TO 
CONTRACTS ENTERED INTO SOLELY BETWEEN RESIDENTS OF, AND TO BE 
PERFORMED ENTIRELY WITHIN, SUCH STATE.

12.3  Survival; Reliance.  The representations and warranties in 
Sections 3 and 4 of this Agreement shall survive any investigation 
made by the Purchasers or the Company for a period of one year 
after the Closing Date in question.  Thereafter, such 
representations and warranties shall expire and be of no further 
force and effect, and no cause of action may be brought with 
respect to any breach thereof unless a written notice specifying 
the nature and the amount of the claims shall have been delivered 
by the Company or the Purchasers, as the case may be, with respect 
thereto, on or before one year after the Closing Date in question.  
Any representation or warranty contained herein may be relied upon 
by counsel to the Company in connection with any opinion delivered 
in connection with the transactions contemplated hereby.

12.4  Successors and Assigns.  This Agreement shall be binding 
upon and shall inure to the benefit of the parties hereto and 
their respective successors and assigns.  Except as otherwise 
provided in this Agreement, this Agreement may not be assigned by 
a party without the prior written consent of the other party 
except by operation of law, in which case the assignee shall be 
subject to all of the provisions of this Agreement.

12.5  Notices and Dates.  Any notice or other communication given 
under this Agreement shall be sufficient if in writing and shall 
be treated as effective or deemed to be given (unless a different 
time period is specified in another Section hereof)  (a) the date 
of receipt if delivered by hand, by messenger or by courier, or 
upon confirmation of receipt if transmitted by facsimile, to a 
party at its address set forth below (or at such other address as 
shall be designated for such purpose by such party in a written 
notice to the other party hereto) or (b) three days after the date 
when the same shall have been posted by registered mail, return 
receipt requested, in any post office in the United States of 
America, postage prepaid and addressed to the party at such 
address:

(i)  if to the Company:

	Aprogenex, Inc.
	8000 El Rio Street
	Houston, Texas  77054-1404
	Attn:  Chief Financial Officer
	(Facsimile) (713) 748-6012

(ii)  if to Purchasers, then to the addresses set forth at Exhibit 
A.

12.6  Specific Performance.  The parties hereto acknowledge and 
agree that irreparable damage would occur in the event any of the 
provisions of this Agreement were not performed in accordance with 
its specific terms or were otherwise breached and that such damage 
would not be compensable in money damages and that it would be 
extremely difficult or impracticable to measure the resultant 
damages.  It is accordingly agreed that any party hereto shall be 
entitled to an injunction or injunctions to prevent breaches of 
the provisions of this Agreement and to enforce specifically the 
terms and provisions hereof, in addition to any other remedy to 
which it may be entitled at law or in equity, and such party that 
is sued for breach of this Agreement expressly waives any defense 
that a remedy in damages would be adequate and expressly waives 
any requirement in an action for specific performance for the 
posting of a bond by the party bringing such action.

12.7  Further Assurances.  The parties hereto shall do and perform 
or cause to be done and performed all such further acts and things 
and shall execute and deliver all such other agreements, 
certificates, instruments or documents as any other party may 
reasonably request from time to time in order to carry out the 
intent and purposes of this Agreement and the consummation of the 
transactions contemplated hereby.

12.8  Counterparts.  This Agreement may be executed in any number 
of counterparts, each of which may be executed by fewer than all 
of the parties, each of which shall be enforceable against the 
parties actually executing such counterparts, and all of which 
together shall constitute one instrument.

12.9  Severability.  In the event that any provision of this 
Agreement becomes or is declared by a court of competent 
jurisdiction to be illegal, unenforceable or void, this Agreement 
shall continue in full force and effect without said provision; 
provided that no such severability shall be effective if it 
materially changes the economic impact of this Agreement on any 
party.

12.10  Captions.  Headings of the various sections of this 
Agreement have been inserted for convenience of reference only and 
shall not be relied upon in construing this Agreement.  Use of any 
gender herein to refer to any person shall be deemed to comprehend 
masculine, feminine and neuter unless the context clearly requires 
otherwise.

12.11  Public Statements.  The Purchasers severally agree not to 
issue any public statement with respect to the Purchasers' 
investment or proposed investment in the Company or the terms of 
any agreement or covenant between them and the Company without the 
Company's prior written consent, except such disclosures as may be 
required under applicable law or under any applicable order, rule 
or regulation.  Each Purchaser hereby agrees that the Company may 
disclose the name and address of such Purchaser, including, 
without limitation, such disclosure as may be required under 
applicable law or under any applicable order, rule or regulation.  

12.12  Brokers.

	(a)  Each Purchaser severally represents and warrants that it 
has not engaged, consented to or authorized any broker, finder or 
intermediary to act on its behalf, directly or indirectly, as a 
broker, finder or intermediary in connection with the transactions 
contemplated by this Agreement.  Each Purchaser hereby severally 
agrees to indemnify and hold harmless the Company from and against 
all fees, commissions or other payments owing to any such person 
or firm acting on behalf of such Purchaser hereunder.

	(b)  The Company represents and warrants that it has not 
engaged, consented to or authorized any broker, finder or 
intermediary to act on its behalf, directly or indirectly, as a 
broker, finder or intermediary in connection with the transactions 
contemplated by this Agreement. The Company agrees to indemnify 
and hold harmless the Purchasers from and against all fees, 
commissions or other payments owing by the Company to any person 
or firm acting on behalf of the Company hereunder.

12.13  Costs and Expenses.  Each party hereto shall pay its own 
costs and expenses incurred in connection herewith, including the 
fees of its counsel, auditors and other representatives, whether 
or not the transactions contemplated herein are consummated.

12.14  No Third-Party Rights.  Nothing in this Agreement shall 
create or be deemed to create any rights in any person or entity 
not a party to this Agreement except for such rights as may exist 
by virtue of any contract or other agreement existing on the date 
hereof.

12.15  Entire Agreement; Integration and Severability.  This 
Agreement, the Notes, the Warrant Agreement  and the other 
documents delivered pursuant hereto constitute the full and entire 
understanding and agreement between the parties with regard to the 
subject matter hereof and thereof and supersede all prior 
agreements and understandings among the parties relating to the 
subject matter hereof.  No party shall be liable or bound to any 
other party in any manner by any warranties, representations or 
covenants except as specifically set forth herein.  

ANY PROVISION OF THIS AGREEMENT WHICH IS PROHIBITED OR 
UNENFORCEABLE IN ANY JURISDICTION SHALL, AS TO SUCH JURISDICTION, 
BE INEFFECTIVE TO THE EXTENT OF SUCH PROHIBITION OR 
UNENFORCEABILITY WITHOUT INVALIDATING THE REMAINING PROVISIONS 
HEREOF, AND ANY SUCH PROHIBITION OR UNENFORCEABILITY IN ANY 
JURISDICTION SHALL NOT INVALIDATE OR RENDER UNENFORCEABLE SUCH 
PROVISION IN ANY OTHER JURISDICTION.

12.16  Consent to Amendments; Waiver of Past Defaults.  This 
Agreement and the Notes related hereto may be amended, and the 
Company may take any action herein prohibited, or omit to perform 
any act herein required to be performed by it, if the Company 
shall obtain the written consent to such amendment, action or 
omission to act of the Holder or Holders of at least 51% of the 
aggregate principal amount of the Notes then Outstanding at a 
record date set by the Company for such written consent, except 
that, without the written consent of the Holder or Holders of all 
Notes at the time Outstanding, no amendment to this Agreement 
shall (i) change the maturity of any Note, or (ii) change the 
principal of, or the rate or time of payment of interest on any 
Note.  The Holders of not less than 51% of the aggregate principal 
amount of the Notes then Outstanding may on behalf of the Holders 
of all the Notes waive any past default hereunder and its 
consequences, except a default (i) in the payment of the principal 
of or interest on any Note, or (ii) in respect of a covenant or 
provision hereof which under this Section 12.16 cannot be modified 
without the consent of the Holder of each Outstanding Note 
affected. Each Holder of any Note at the time or thereafter 
Outstanding shall be bound by any consent or waiver authorized by 
this Section 12.16, whether or not such Note shall have been 
marked to indicate such consent or waiver, but any Notes issued 
thereafter may bear a notation referring to any such consent or 
waiver.  No course of dealing between the Company and the Holder 
of any Note nor any delay in exercising any rights hereunder or 
under any Note shall operate as a waiver of any rights of any 
Holder of such Note.  Notwithstanding the foregoing provisions of 
this Section, waivers and amendments relating to Section 8.1  
hereof shall be determined by and in accordance with Section 
8.1(i).  As used herein and in the Notes, the term this Agreement 
and references thereto shall mean this Agreement as it may from 
time to time be amended or supplemented.


Signature Page

_______________________________________
Principal Amount of Notes Subscribed For

____________________________________________________
Names(s) Exactly as to Appear on Note Certificate

												
Signature						Signature (if purchasing 
jointly)

												
Name Typed or Printed					Name Typed or 
Printed

												
Residence Address					Residence Address

												
City, State and Zip Code					City, State and Zip 
Code

												
Telephone--Business					Telephone--Business

												
Telephone--Residence					Telephone--Residence

												
Tax Identification or Social Security No.			Tax 
Identification or Social Security No.

NASD Affiliation or Association, if any:						
	
	If None, check here:______

Name in which securities should be issued:					
		

Dated:			 	, 1996

	
This Convertible Note Subscription Agreement is agreed to and 
accepted as of _________ ____, 1996.
						APROGENEX, INC.


												
						By:  J. Donald Payne 
						Its:  Vice President 


CERTIFICATE OF SIGNATORY

(To be completed if Notes are being subscribed for by an entity)


I, _________________, am the _______________ of 
________________________ (the Entity).

I certify that I am empowered and duly authorized by the Entity to 
execute and carry out the terms of the Note Subscription Agreement 
and to purchase and hold the Notes, and certify further that the 
Note Subscription Agreement has been duly and validly executed on 
behalf of the Entity and constitutes a legal and binding 
obligation of the Entity.

IN WITNESS WHEREOF, I have set my hand this ____ day of 
______________, 1996.


	By:  					


EXHIBIT A

SCHEDULE OF PURCHASERS

NOT INCLUDED



EXHIBIT B

WARRANT AGREEMENT



See Exhibit 4.2 to this Form 8-K

EXHIBIT C

ESCROW AGREEMENT



Not included.

EXHIBIT D

SCHEDULE OF EXCEPTIONS

The exceptions set forth below are made to the representations and 
warranties of Aprogenex, Inc. (the Company) in Section 3 of the 
Convertible Note Subscription Agreement dated as of May 1, 1996 
(the Agreement).  Except as otherwise defined herein, all 
capitalized terms used herein shall have the meanings given them 
in the Agreement.  Section numbers used herein correspond to 
section numbers in the Agreement.  Exceptions set forth herein 
relate to the captioned section number and any other applicable 
sections of the Agreement. 


NONE

EXHIBIT E

INVESTOR QUESTIONNAIRE

NOT INCLUDED


EXHIBIT F

Aprogenex, Inc.
Irrevocable Notice of Conversion of Convertible Note


NOT INCLUDED





Exhibit 4.1(b)
[FORM OF NOTE]

THE SECURITIES EVIDENCED HEREBY HAVE BEEN ACQUIRED FOR INVESTMENT 
AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS 
AMENDED OR ANY STATE SECURITIES LAWS. NO SALE OR DISPOSITION MAY 
BE EFFECTED WITHOUT (i) EFFECTIVE REGISTRATION STATEMENTS RELATED 
THERETO, (ii) AN OPINION OF COUNSEL FOR THE INVESTOR, REASONABLY 
SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATIONS ARE NOT 
REQUIRED AND THAT ANY APPLICABLE  PROSPECTUS DELIVERY REQUIREMENTS 
ARE NOT APPLICABLE OR (iii) RECEIPT OF NO-ACTION LETTERS FROM THE 
APPROPRIATE GOVERNMENTAL AUTHORITIES. THESE SECURITIES WERE 
OBTAINED FROM THE COMPANY UNDER AN AGREEMENT THAT INCLUDES 
ADDITIONAL RESTRICTIONS ON TRANSFER AND COPIES OF SUCH AGREEMENT 
MAY BE OBTAINED AT NO COST BY WRITTEN REQUEST MADE BY THE HOLDER 
OF RECORD OF THIS CERTIFICATE TO THE SECRETARY OF THE COMPANY AT 
THE PRINCIPAL EXECUTIVE OFFICES OF THE COMPANY.

APROGENEX, INC.

CONVERTIBLE NOTE

HOUSTON, TEXAS	No. ____

________ ___, 1996	$____________

FOR VALUE RECEIVED, APROGENEX, INC., a Delaware corporation (the 
Company), hereby promises to pay to [Name of Payee], the principal 
sum of [Principal Amount of Note] together with interest on the 
unpaid balance of said principal sum from the date hereof at the 
rate per annum equal to the lesser of (i) 10% and (ii) the maximum 
non-usurious contract rate of interest allowed from time to time 
by applicable law (the Highest Lawful Rate), in each case, 
calculated on the basis of a year of 365 days, for the actual 
number of days elapsed.  Unless converted earlier as provided 
below, all principal and accrued interest on this Note shall be 
due and payable on May 29. 1998, 1998. No interest will be payable 
until maturity of the Note, but will accrue at the rate set forth 
above; the amount of such accrued interest shall compound 
quarterly on the 15th day of each February, May, August and 
November that this Note is outstanding and unpaid.  All payments 
will be made in New York City as specified in the Agreement (as 
defined below).  

This Note is one of a series of notes of similar tenor being 
issued at this time (the Notes) pursuant to a Convertible Note 
Subscription Agreement (the Agreement) among the Company and the 
purchasers named therein, to which Agreement and all agreements 
supplemental thereto reference is hereby made for a statement of 
certain of the respective rights thereunder of the Company and the 
holders of the Notes, and the terms upon which the Notes are, and 
are to be, issued.  This Note is entitled to the rights and 
subject to the limitations relating to Notes that are included in 
the Agreement.  This Note is an unsecured obligation of the 
Company.  
 
The Notes are redeemable upon the terms and conditions set forth 
in the Agreement. The Notes are redeemable at a price equal to 
100% of the principal amount of the Notes to be redeemed together 
with accrued and unpaid interest to the date fixed by the Company 
for such redemption.

The entire unpaid principal sum of this Note, together with 
accrued and unpaid interest thereon, shall become immediately due 
and payable upon the insolvency of the Company, the commission of 
any act of bankruptcy by the Company, the execution by the Company 
of a general assignment for the benefit of creditors, the filing 
by or against the Company of any petition in bankruptcy or any 
petition for relief under the provisions of the federal bankruptcy 
act or any other state or federal law for the relief of debtors 
and the continuation of such petition without dismissal for a 
period of thirty (30) days or more, or the appointment of a 
receiver or trustee to take possession of the property or assets 
of the Company. 

The Agreement permits, with certain exceptions as therein 
provided, the amendment thereof and the modification of the rights 
and obligations of the Company and the rights of the holders of 
the Notes under the Agreement at any time by the Company with the 
consent of the holders of 51% in aggregate principal amount of the 
Notes at the time outstanding, as defined in the Agreement.  The 
Agreement also contains provisions permitting the holders of 51% 
in aggregate principal amount of the Notes at the time Outstanding 
(as defined in the Agreement) on behalf of all the holders of all 
the Notes, by written consent to waive compliance by the Company 
with certain provisions of the Agreement and certain past defaults 
under the Agreement and their consequences. Any such consent or 
waiver by the holder of this Note shall be conclusive and binding 
upon such holder and upon all future holders of this Note and of 
any Note issued upon the transfer hereof or in exchange herefor or 
in lieu hereof whether or not notation of such consent and waiver 
is made upon this Note.

The holder of this Note may convert the principal of and related 
accrued and unpaid interest on this Note, subject to the terms and 
conditions of the Agreement, into shares of common stock of the 
Company, par value $.001 per share (Common Stock) at a conversion 
price that initially shall be $1.10 per share of Common Stock, 
which conversion price is subject to adjustment from time to time 
as provided in the Agreement.  If any fraction of a share of 
Common Stock  would otherwise be issuable on the conversion of any 
of the Notes, the Company instead shall pay an amount in  cash 
(computed to the nearest cent) equal to the then Fair Value (as 
defined in the Agreement) of a share of Common Stock  multiplied 
by such fraction.

Prior to due presentment for registration of transfer, the Company 
may treat the person in whose name this Note is registered as the 
owner and holder of this Note for the purpose of receiving payment 
of principal of and interest on this Note and for all other 
purposes whatsoever, whether or not this Note shall be overdue, 
and the Company shall not be affected by notice to the contrary. 

Regardless of any provision contained herein, or in any other 
document executed in connection herewith, the holder hereof shall 
never be entitled to receive, collect or apply, as interest 
hereon, any unearned interest or any amount in excess of the 
Highest Lawful Rate, and in the event the holder hereof ever 
receives, collects or applies, as interest, any unearned interest 
or any such excess, such amount shall be deemed a partial 
prepayment of principal, and, if the principal hereof is paid in 
full, any remaining excess shall forthwith be refunded to the 
Company.  In determining whether or not the interest paid or 
payable, under any specific contingency, exceeds the Highest 
Lawful Rate, the Company and the holder hereof shall, to the 
maximum extent permitted by law, (a) characterize any non 
principal payment as an expense or fee rather than as interest, 
(b) exclude voluntary prepayment and the effects thereof and 
(c) amortize, prorate, allocate and spread, in equal parts, the 
total amount of interest throughout the entire contemplated term 
of this Note so that the interest rate is uniform throughout the 
entire term hereof.

In the event of any successful action to collect this Note, the 
Company shall pay all costs and expenses of collection of the 
holder of this Note, including reasonable attorneys' fees.

The Company and all endorsers, guarantors and assignors, if any, 
of this Note severally waive notice of default, presentation or 
demand for payment and protest and notice of nonpayment or 
dishonor.

This Note was issued with original issue discount.  A holder 
should direct to the Company, Attn: Vice President - Finance, 8000 
El Rio Street, Houston, Texas 77054-4104, telephone number (713) 
748-5114, fax number (713) 748-6012, any questions regarding the 
issue price, the amount of the original issue discount, the issue 
date, or the yield to maturity with respect to the Note.

The provisions of this Note shall be governed by, and 
construed in accordance with, the laws of the State of New 
York, without reference to principles of conflicts of law, 
and applicable federal law.

IN WITNESS WHEREOF, the Company has caused this Note to be 
executed as of the date first hereinabove set forth.

	APROGENEX, INC.


	By: 					
		J. Donald Payne
		Vice President - Finance
	







Exhibit 4.2
WARRANT AGREEMENT


THIS WARRANT AGREEMENT (the Agreement), dated as of May 1, 1996, 
is made and entered into by and among Aprogenex, Inc., a Delaware 
corporation (the Company), and those persons set forth on Schedule 
1 hereto (the Warrantholders).  This Agreement is being executed 
in connection with the Convertible Note Subscription Agreement of 
even date herewith by and among the Company and the Warrantholders 
(the Purchase Agreement).  

The Company agrees to issue and sell, and the Warrantholder agrees 
to purchase, for an agreed value of $.10 per share, warrants, as 
hereinafter described (the Warrants), to purchase up to an 
aggregate of the number of shares set forth on Schedule 1 (the 
Shares), of the Company's Common Stock, par value $.001 per share 
(the Common Stock).  The purchase and sale of the Warrants shall 
occur contemporaneous with, and is subject to the closing of the 
Purchase Agreement.

In consideration of the foregoing and for the purpose of defining 
the terms and provisions of the Warrants and the respective rights 
and obligations thereunder, the Company and the Warrantholder, for 
value received, hereby agree as follows:

Section 1. Transferability and Form of Warrants.

1.1  Registration.  The Warrants shall be numbered and shall be 
registered on the books of the Company when issued.

1.2  Transfer.  The Warrant shall not be transferable.  Any 
attempted sale, assignment, pledge, hypothecation or other 
transfer shall be void and will not be recognized by the Company.

1.3  Limitations on Transfer of the Shares.  The Warrants 
shall not be transferrable and the Shares shall not be sold, 
assigned, transferred or pledged except upon the conditions 
specified in this Agreement.  The Warrantholder will cause any 
proposed purchaser, assignee, transferee or pledgee of the Shares 
or, except for dispositions that are pursuant to an effective 
registration statement under the Act (as defined herein) or 
dispositions pursuant to Rule 144, to agree to take and hold such 
securities subject to the provisions and upon the conditions 
specified in this Agreement.  The Warrants may be divided or 
combined, upon request to the Company by the Warrantholder, into a 
certificate or certificates representing the right to purchase the 
same aggregate number of Shares.  Unless the context indicates 
otherwise, the term Warrantholder shall include any transferee or 
transferees of the Shares that is required to be bound by the 
terms hereof, and the term Warrants shall include any and all 
warrants outstanding pursuant to this Agreement, including those 
evidenced by a certificate or certificates issued upon division, 
exchange or substitution pursuant to this Agreement.  The 
Warrantholder by his receipt of a Warrant Certificate, agrees to 
be bound by and comply with the terms of this Agreement.  The 
Warrantholder represents and agrees that the Warrant (and Shares 
if the Warrant is exercised) is purchased only for investment, for 
the Warrantholder's own account, and without any present intention 
to sell, or with a view to distribution of, the Warrant or Shares.

1.4  Form of Warrants.  The text of the Warrants and of the 
form of election to purchase Shares shall be substantially as set 
forth in Exhibit A attached hereto.  The number of Shares issuable 
upon exercise of the Warrants is subject to adjustment upon the 
occurrence of certain events, all as hereinafter provided.  The 
Warrant shall be executed on behalf of the Company by its 
President or by a Vice President, attested to by its Secretary or 
an Assistant Secretary.  A Warrant bearing the signature of an 
individual who was at any time the proper officer of the Company 
shall bind the Company, notwithstanding that such individual shall 
have ceased to hold such office prior to the delivery of such 
Warrant or did not hold such office on the date of this Agreement.

The Warrants shall be dated as of the date of signature thereof by 
the Company either upon initial issuance or upon division, 
exchange or substitution.

1.5  Legend on Warrants.  Each Warrant Certificate shall bear 
the following legend:

(a)	THE WARRANTS REPRESENTED BY THIS CERTIFICATE HAVE BEEN 
ACQUIRED FOR INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER 
THE SECURITIES ACT OF 1933, AS AMENDED, OR ANY STATE 
SECURITIES LAW.  SUCH WARRANTS ARE NOT TRANSFERRABLE AND 
ANY ATTEMPTED TRANSFER SHALL BE VOID AND NOT RECOGNIZED BY 
THE COMPANY. COPIES OF THE WARRANT AGREEMENT AND THE 
PURCHASE AGREEMENT COVERING THE PURCHASE OF THESE WARRANTS 
AND VARIOUS REQUIREMENTS, INCLUDING WITHOUT LIMITATION 
PROVISIONS PROHIBITING THEIR TRANSFER, MAY BE OBTAINED AT 
NO COST BY WRITTEN REQUEST MADE BY THE HOLDER OF RECORD OF 
THIS CERTIFICATE TO THE SECRETARY OF THE CORPORATION AT THE 
PRINCIPAL EXECUTIVE OFFICES OF THE CORPORATION.

(b)  any legend required by applicable state securities law.

Any certificate issued at any time in exchange or substitution for 
any certificate bearing such legends (except in the case of the 
Shares, a new certificate issued upon completion of a public 
distribution pursuant to a registration statement under the 
Securities Act of 1933, as amended (the Act), or upon completion 
of a sale under Rule 144 under the Act of the securities 
represented thereby) shall also bear the above legends unless, in 
the opinion of the Company's counsel, the securities represented 
thereby need no longer be subject to such restrictions.  The 
Warrantholder consents to the Company making a notation on its 
records and giving instructions to any registrar or transfer agent 
of the Warrants and the Common Stock in order to implement the 
restrictions on transfer established in this Agreement.

Section 2.  Exchange of Warrant Certificate.  Any Warrant 
certificate may be exchanged for another certificate or 
certificates entitling the Warrantholder to purchase a like 
aggregate number of Shares as the certificate or certificates 
surrendered then entitled such Warrantholder to purchase.  Any 
Warrantholder desiring to exchange a Warrant certificate shall 
make such request in writing delivered to the Company, and shall 
surrender, properly endorsed, with signatures guaranteed, the 
certificate evidencing the Warrant to be so exchanged.  Thereupon, 
the Company shall execute and deliver to the person entitled 
thereto a new Warrant certificate as so requested.

Section 3.  Term of Warrants; Exercise of Warrants.

(a)  Subject to the terms of this Agreement, the Warrantholder 
shall have the right, at any time and from time to time during the 
period commencing after both (i) the date of this Agreement and 
(ii) the American Stock Exchange's approval of the listing of the 
Shares, and ending at 5:00 p.m., Houston, Texas Time, on May 28, 
1999 (the Termination Date), to purchase from the Company up to 
the number of fully paid and nonassessable Shares to which the 
Warrantholder may at the time be entitled to purchase pursuant to 
this Agreement, upon surrender to the Company, at its principal 
office, of the certificate evidencing the Warrants to be 
exercised, together with the purchase form on the reverse thereof 
duly filled in and signed, with signatures guaranteed, and upon 
payment to the Company of the Warrant Price (as defined in and 
determined in accordance with the provisions of this section 3 and 
sections 7 and 8 hereof), for the number of Shares in respect of 
which such Warrants are then exercised, but in no event for less 
than 100 Shares for any Warrantholder (unless less than an 
aggregate of 100 Shares are then purchasable under all outstanding 
Warrants held by a Warrantholder).  Notwithstanding any other 
provisions of this Agreement, the issuance of the Shares will 
require the approval of the American Stock exchange which approval 
the Company will seek to obtain promptly after the closing of this 
Agreement.

(b)  Payment by each Warrantholder of the aggregate Warrant Price 
due from him shall be made in cash or by immediately available 
funds, check or any combination thereof.

(c)  Upon such surrender of the Warrants and payment of such 
Warrant Price as aforesaid, the Company shall issue and cause to 
be delivered to or upon the written order of the exercising 
Warrantholder and in such name or names as the exercising 
Warrantholder may designate (which in no way shall limit the 
transfer restrictions hereunder) a certificate or certificates for 
the number of full Shares so purchased upon the exercise of his 
Warrant, together with cash, as provided in Section 9 hereof, in 
respect of any fractional Shares otherwise issuable upon such 
surrender.  Such certificate or certificates shall be deemed to 
have been issued and any person so designated to be named therein 
shall be deemed to have become a holder of record of such 
securities as of the date of surrender of the Warrants and payment 
of the Warrant Price, as aforesaid, notwithstanding that the 
certificate or certificates representing such securities shall not 
actually have been delivered or that the stock transfer books of 
the Company shall then be closed.  The Warrants shall be 
exercisable, at the election of the Warrantholder, either in full 
or from time to time in part and, in the event that a certificate 
evidencing the Warrants is exercised in respect of less than all 
of the Shares specified therein at any time prior to the 
Termination Date, a new certificate evidencing the remaining 
portion of the Warrants held by the Warrantholder will be issued 
by the Company.

Section 4.  Payment of Taxes.  The Company will pay all 
documentary stamp taxes, if any, attributable to the initial 
issuance of the Warrants or the securities comprising the Shares; 
provided, however, the Company shall not be required to pay any 
tax which may be payable in respect of any secondary transfer of 
the securities comprising the Shares.

Section 5.  Mutilated or Missing Warrants.  In case the 
certificate or certificates evidencing the Warrants shall be 
mutilated, lost, stolen or destroyed, the Company shall, at the 
request of a Warrantholder, issue and deliver in exchange and 
substitution for and upon cancellation of the mutilated 
certificate or certificates, or in lieu of and substitution for 
the certificate or certificates lost, stolen or destroyed, a new 
Warrant certificate or certificates of like tenor and representing 
an equivalent right or interest, but only upon receipt of evidence 
satisfactory to the Company of such loss, theft or destruction of 
such Warrant and a bond of indemnity, if requested, also 
satisfactory in form and amount at the applicant's cost.  
Applicants for such substitute Warrants certificate shall also 
comply with such other reasonable regulations and pay such other 
reasonable charges as the Company may prescribe.

Section 6.  Reservation of Shares.  There has been reserved, 
and the Company shall at all times keep reserved so long as the 
Warrants remain outstanding, out of its authorized Common Stock, 
such number of shares of Common Stock as shall be subject to 
purchase under the Warrants. Every transfer agent for the Common 
Stock and other securities of the Company issuable upon the 
exercise of the Warrants will be irrevocably authorized and 
directed at all times to reserve such number of authorized shares 
and other securities as shall be requisite for such purpose.  The 
Company will keep a copy of this Agreement on file with every 
transfer agent for the Common Stock and other securities of the 
Company issuable upon the exercise of the Warrants.  The Company 
will supply every such transfer agent with duly executed stock and 
other certificates, as appropriate, for such purpose and will 
provide or otherwise make available any cash which may be payable 
as provided in Section 9 hereof.  On or before taking any action 
that would cause an adjustment pursuant to the terms of the 
Warrants resulting in an increase in the number of shares of 
Common Stock deliverable upon such conversion or exercise above 
the number thereof previously authorized, reserved and available 
therefor, the Company shall take all such action so required for 
compliance with this Section.

Section 7.  Warrant Price.  The price per Share at which Shares 
shall be purchasable upon the exercise of the Warrants (the 
Warrant Price) shall be as set forth in the Warrant, subject to 
further adjustment pursuant to Section 8 hereof.

Section 8.  Adjustment of Number of Shares.  The number and 
kind of securities purchasable upon the exercise of the Warrants 
and the Warrant Price shall be subject to adjustment from time to 
time upon the happening of certain events, as follows:

8.1  Adjustments.  The number of Shares purchasable upon the 
exercise of the Warrants shall be subject to adjustment as 
follows:

(a)  In case the Company shall (i) pay a dividend in Common Stock 
or make a distribution in Common Stock, (ii) subdivide its 
outstanding Common Stock, (iii) combine its outstanding Common 
Stock into a smaller number of shares of Common Stock or (iv) 
issue by reclassification of its Common Stock other securities of 
the Company, the number of Shares purchasable upon exercise of the 
Warrants immediately prior thereto shall be adjusted so that the 
Warrantholder shall be entitled to receive the kind and number of 
Shares or other securities of the Company which it would have 
owned or would have been entitled to receive immediately after the 
happening of any of the events described above had the Warrants 
been exercised immediately prior to the happening of such event or 
any record date with respect thereto.  Any adjustment made 
pursuant to this subsection 8.1(a) shall become effective 
immediately after the effective date of such event retroactive to 
the record date, if any, for such event.

(b)  In case the Company shall issue rights, options, warrants or 
convertible securities to all or substantially all holders of its 
Common Stock, without any charge to such holders, entitling them 
to subscribe for or purchase Common Stock at a price per share 
which is lower at the record date mentioned below than the then 
Fair Value (as defined in Section 9), the number of Shares 
thereafter purchasable upon the exercise of each Warrant shall be 
determined by multiplying the number of Shares theretofore 
purchasable upon exercise of the Warrant by a fraction, of which 
the numerator shall be the number of shares of Common Stock 
outstanding immediately prior to the issuance of such rights, 
options, warrants or convertible securities plus the number of 
additional shares of Common Stock offered for subscription or 
purchase, and of which the denominator shall be the number of 
shares of Common Stock outstanding immediately prior to the 
issuance of such rights, options, warrants or convertible 
securities plus the number of shares which the aggregate offering 
price of the total number of shares offered would purchase at such 
Fair Value.  Such adjustment shall be made whenever such rights, 
options, warrants or convertible securities are issued, and shall 
become effective immediately and retroactive to the record date 
for the determination of shareholders entitled to receive such 
rights, options, warrants or convertible securities.

(c)  In case the Company shall distribute to all or substantially 
all holders of its Common Stock evidences of its indebtedness or 
assets (excluding cash dividends or distributions out of earnings) 
or rights, options, warrants or convertible securities containing 
the right to subscribe for or purchase Common Stock (excluding 
those referred to in subsection 8.1(b) above), then in each case 
the number of Shares thereafter purchasable upon the exercise of 
the Warrants shall be determined by multiplying the number of 
Shares theretofore purchasable upon exercise of the Warrants by a 
fraction, of which the numerator shall be the then Fair Value per 
share of Common Stock on the record date for such distribution, 
and of which the denominator shall be such Fair Value on such date 
minus the then Fair Value of the portion of the assets or 
evidences of indebtedness so distributed or of such subscription 
rights, options, warrants or convertible securities applicable to 
one share.  Such adjustment shall be made whenever any such 
distribution is made and shall become effective on the date of 
distribution retroactive to the record date for the determination 
of shareholders entitled to receive such distribution.

(d)  No adjustment in the number of Shares purchasable pursuant to 
the Warrants shall be required unless such adjustment would 
require an increase or decrease of at least three percent in the 
number of Shares then purchasable upon the exercise of the 
Warrants or, if the Warrants are not then exercisable, the number 
of Shares purchasable upon the exercise of the Warrants on the 
first date thereafter that the Warrants become exercisable; 
provided, however, that any adjustments which by reason of this 
subsection 8.1(d) are not required to be made immediately shall be 
carried forward and taken into account in any subsequent 
adjustment.

(e)  Whenever the number of Shares purchasable upon the exercise 
of the Warrant is adjusted, as herein provided, the Warrant Price 
payable upon exercise of the Warrant shall be adjusted by 
multiplying such Warrant Price immediately prior to such 
adjustment by a fraction, of which the numerator shall be the 
number of Shares purchasable upon the exercise of the Warrant 
immediately prior to such adjustment, and of which the denominator 
shall be the number of Shares so purchasable immediately 
thereafter.

(f)  Whenever the number of Shares purchasable upon the exercise 
of the Warrants is adjusted as herein provided, the Company shall 
cause to be promptly mailed to the Warrantholder by first class 
mail, postage prepaid, notice of such adjustment and a certificate 
of the chief financial officer of the Company setting forth the 
number of Shares purchasable upon the exercise of the Warrants 
after such adjustment, a brief statement of the facts requiring 
such adjustment and the computation by which such adjustment was 
made.

(g)  For the purpose of this subsection 8.1, the term Common Stock 
shall mean (i) the class of stock designated as the Common Stock 
of the Company at the date of this Agreement or (ii) any other 
class of stock resulting from successive change or 
reclassifications of such Common Stock consisting solely of 
changes in par value, or from par value to no par value, or from 
no par value to par value.  In the event that at any time, as a 
result of an adjustment made pursuant to this Section 8, the 
Warrantholder shall become entitled to purchase any securities of 
the Company other than Common Stock, (i) if the Warrantholder's 
right to purchase is on any other basis than that available to all 
holders of the Company's Common Stock, the Company shall obtain an 
opinion of an independent investment banking firm valuing such 
other securities and (ii) thereafter the number of such other 
securities so purchasable upon exercise of the Warrants shall be 
subject to adjustment from time to time in a manner and on terms 
as nearly equivalent as practicable to the provisions with respect 
to the Shares contained in this Section 8.

(h)  Upon the expiration of any rights, options, warrants or 
conversion privileges, if such shall not have been exercised, the 
number of Shares purchasable upon exercise of Warrants, to the 
extent the Warrants have not then been exercised, shall, upon such 
expiration, be readjusted and shall thereafter be such as they 
would have been had they been originally adjusted (or had the 
original adjustment not been required, as the case may be) on the 
basis of (i) the fact that Common Stock, if any, actually issued 
or sold upon the exercise of such rights, options, warrants or 
conversion privileges, and (ii) the fact that such shares of 
Common Stock, if any, were issued or sold for the consideration 
actually received by the Company upon such exercise plus the 
consideration, if any, actually received by the Company for the 
issuance, sale or grant of all such rights, options, warrants or 
conversion privileges whether or not exercised; provided, however, 
that no such readjustment shall have the effect of decreasing the 
number of Shares purchasable upon exercise of the Warrants by an 
amount in excess of the amount of the adjustment initially made in 
respect of the issuance, sale or grant of such rights, options, 
warrants or conversion privileges.

8.2  No Adjustment for Certain Matters.  During the term of 
the Warrants or upon the exercise of the Warrants, no adjustment 
shall be made (i) except as provided in subsection 8.1 in respect 
of any dividends or distributions out of earnings or (ii) in 
respect of the consummation of any action described in Section 
10(b).  Without limiting the generality of the foregoing, the 
Company shall have no obligation to cause any purchaser or 
successor by merger, sale of assets or similar business 
combination to assume the obligations under this Agreement.

8.3  Par Value of Shares of Common Stock.  Before taking any 
action which would cause an adjustment effectively reducing the 
portion of the Warrant Price allocable to each Share below the  
then par value per share of the Common Stock issuable upon 
exercise of the Warrants, the Company will take any corporate 
action which may, in the opinion of its counsel, be necessary in 
order that the Company may validly and legally issue fully paid 
and nonassessable Common Stock upon exercise of the Warrants.

8.4  Independent Public Accountants.  The Company may retain 
a firm of independent public accountants of recognized national 
standing (which may be any such firm regularly employed by the 
Company)  to make any computation required under this Section 8, 
and a certificate signed by such firm shall be conclusive evidence 
of the correctness of any computation made under this Section 8.

8.5  Statement on Warrant Certificates.  Irrespective of any 
adjustments in the number of securities issuable upon exercise of 
Warrants, Warrant certificates theretofore or thereafter issued 
may continue to express the same number of securities as are 
stated in the similar Warrant certificates initially issuable 
pursuant to this Agreement.  However, the Company may, at any time 
in its sole discretion (which shall be conclusive), make any 
change in the form of Warrant certificate that it may deem 
appropriate and that does not affect the substance thereof;  and 
any Warrant certificate thereafter issued, whether upon 
registration of, or in exchange or substitution for, an 
outstanding Warrant certificate, may be in the form so changed.

Section 9.  Fractional Interests; Fair Value.  The Company 
shall not be required to issue fractional Shares on the exercise 
of the Warrants.  If any fraction of a Share would, except for the 
provisions of this Section 9, be issuable on the exercise of the 
Warrants (or specified portion thereof), the Company shall pay an 
amount in cash equal to the then Fair Value of the Common Stock 
multiplied by such fraction.  As used herein, the term Fair Value 
of the Common Stock or other Securities or other property shall 
mean the fair value as determined in good faith by the Company's 
Board of Directors, which determination shall be binding upon the 
Warrantholder; provided, however, that Fair Value of the Common 
Stock for any day shall mean the last sales price, regular way, on 
the day in question or, in case no such sale takes place on such 
day, the average of the closing bid and asked prices, regular way, 
on such day, in either case as reported in the principal 
transaction reporting system with respect to securities listed or 
admitted to trading on the American Stock Exchange, or, if such 
security is not listed or admitted to trading on the American 
Stock Exchange, on the principal national securities exchange on 
which such security is listed or admitted to trading, or, if such 
security is not listed or admitted to trading on any national 
securities exchange but sales price information is reported for 
such security, as reported by NASDAQ or such other self-regulatory 
organization or registered securities information processor (as 
such terms are used under the Securities Exchange Act of 1934, as 
amended) that then reports information concerning such security, 
or, if sales price information is not so reported, the average of 
the high bid and low asked prices in the over-the-counter market 
on such day, as reported by NASDAQ or such other entity, or, if on 
such day such security is not quoted by any such entity, the 
average of the closing bid and asked prices as furnished by a 
professional market maker making a market in such security 
selected by the Board of Directors of the Company.  If on such day 
no market maker is making a market in such security, the fair 
value of such security on such day as determined in good faith by 
the Board of Directors of the Company shall be used.

Section 10.  No Right as Stockholder; Notices to 
Warrantholder.  Nothing contained in this Agreement or in the 
Warrants shall be construed as conferring upon the Warrantholder 
any rights as a stockholder of the Company, including the right to 
vote, receive dividends, consent or receive notices as a 
stockholder in respect of any meeting of stockholders for the 
election of directors of the Company or any other matter.  If, 
however, at any time prior to the expiration of the Warrants and 
prior to their exercise, any one or more of the following events 
shall occur:

(a)  any action which would require  an adjustment pursuant to 
Section 8.1 (except subsections 8.1(e) and 8.1(g)); or

(b)  a dissolution, liquidation or winding up of the Company or a 
consolidation, merger or similar business combination or sale of 
its property, assets and business as an entirety or substantially 
as an entirety shall be proposed;

then the Company shall give notice in writing of such event to the 
Warrantholder, as provided in Section 10 hereof, promptly prior to 
the date fixed as a record date or the date of closing the 
transfer books for the determination of the stockholders entitled 
to any relevant dividend, distribution, subscription rights or 
other rights, or for the determination of stockholders entitled to 
vote on such proposed dissolution, liquidation or winding up.  
Such notice shall specify such record date or the date of closing 
the transfer books, as the case may be.  Failure to mail or 
receive such notice or any defect therein shall not affect the 
validity of any action taken with respect thereto.

Section 11.  Securities Laws; Restrictions on Transfer of 
Shares; Registration Rights.

11.1  Compliance with Securities Act.  

(a)  Initial and Continuing Compliance.  The Warrantholder 
agrees that this Warrant and the related Shares (each of the 
Warrant and the Shares being referred to herein as a Security and 
together, Securities) are being acquired for investment and that 
such Warrantholder will not purchase, offer, sell or otherwise 
dispose of any of the Securities except under circumstances which 
will not result in a violation of the Act.  In order to exercise 
this Warrant, the Warrantholder must be able to confirm and shall 
confirm in writing, by executing a certificate to be supplied by 
the Company, all of the representations and other covenants 
contained in this Agreement, including that the Securities so 
purchased are being acquired for investment and not with a view 
toward distribution or resale.  The Shares (unless registered 
under the Act) shall be stamped or imprinted with, in addition to 
any other appropriate or required legend, a legend in 
substantially the following form:

THE SECURITIES EVIDENCED HEREBY HAVE NOT BEEN REGISTERED 
UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR ANY STATE 
SECURITIES LAWS.  NO SALE OR DISPOSITION MAY BE EFFECTED 
WITHOUT (i) AN EFFECTIVE REGISTRATION STATEMENT RELATED 
THERETO, (ii) AN OPINION OF COUNSEL FOR THE HOLDER, 
REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH 
REGISTRATION IS NOT REQUIRED AND ANY PROSPECTUS DELIVERY 
REQUIREMENTS ARE NOT APPLICABLE, (iii) RECEIPT OF NO-ACTION 
LETTERS FROM THE APPROPRIATE GOVERNMENTAL AUTHORITIES. 
COPIES OF THE AGREEMENT COVERING THE PURCHASE OF THESE 
SECURITIES AND RESTRICTING THEIR TRANSFER MAY BE OBTAINED 
AT NO COST BY WRITTEN REQUEST MADE BY THE HOLDER OF RECORD 
OF THIS CERTIFICATE TO THE SECRETARY OF THE COMPANY AT THE 
PRINCIPAL EXECUTIVE OFFICES OF THE COMPANY.

In addition, the Warrantholder specifically represents to the 
Company both at the time of initial purchase of the Warrant and at 
those future times as specified herein:

(1)  The Warrantholder has experience in analyzing and investing 
in companies like the Company and is capable of evaluating the 
merits and risks of an investment in the Company and has the 
capacity to protect its own interests.  The Warrantholder is an 
Accredited Investor as that term is defined in Rule 501(a) 
promulgated under the Act.  The Warrantholder is aware of the 
Company's business affairs and financial condition, and has 
acquired information about the Company sufficient to reach an 
informed and knowledgeable decision to acquire the Securities.  
The Warrantholder is acquiring the Securities for its own account 
for investment purposes only not as a nominee or agent and not 
with a view to, or for the resale in connection with, any 
distribution thereof for purposes of the Act.  The Warrantholder 
is acquiring the Securities for investment for its own account, 
not as a nominee or agent, and not with a view to, or for resale 
in connection with, any distribution thereof. The Warrantholder 
acknowledges the Company's obligation to include the Shares in 
certain registration statements as set forth in the Warrant 
Agreement, the effectiveness of which registration statements may 
be required for the resale of the Shares.  Without limiting the 
generality of the preceding sentences of this Section, the 
Warrantholder has not offered or sold any portion of the 
Securities to be acquired by such Warrantholder and has no present 
intention of reselling or otherwise disposing of any portion of 
such Securities either currently or after the passage of a fixed 
or determinable period of time or upon the occurrence or 
nonoccurrence of any predetermined event or circumstance, and in 
particular the Warrantholder has no current intention to resell 
the Shares under such registration statements nor would it have 
such intention if such registration statements were effective as 
of the date of this representation.  The Warrantholder understands 
that investment in the Securities is subject to a high degree of 
risk.  The Warrantholder can bear the economic risk of its 
investment, including the full loss of its investment, and by 
reason of its business or financial experience or the business or 
financial experience of its professional advisors has the capacity 
to evaluate the merits and risks of its investment and protect its 
own interest in connection with the purchase of the Securities.  
The Warrantholder represents that it does not have any contract, 
undertaking, agreement or arrangement with any person to sell, 
transfer or grant participation to such person or to any third 
person, with respect to any of the Securities and will make no 
attempt to transfer the Warrants.  If other than an individual, 
the Warrantholder also represents it has not been organized for 
the purpose of acquiring the Securities.  The Warrantholder's 
purchase is not and will not be part of a plan or scheme to evade 
the registration requirements of the Act.

(2)  The Warrantholder understands that the Securities have not 
been and except as provided in this Agreement with respect to the 
Shares will not be registered under the Act or any applicable 
state securities law in reliance upon a specific exemption 
therefrom, which exemption depends upon, among other things, the 
bona fide nature of the Warrantholder's investment intent as 
expressed herein and the accuracy of the Warrantholder's 
representations as expressed herein and the Warrantholder will 
furnish the Company with such additional information as is 
reasonably requested by the Company in connection with such 
exemption.  

(3)  The Warrantholder further understands that the Securities 
must be held indefinitely unless subsequently registered under the 
Act and any applicable state securities laws, or unless exemptions 
from registration are otherwise available.  Moreover, the 
Warrantholder understands that the Company is under no obligation 
to and does not expect to register the Securities except as 
provided for in this Agreement with respect to the Shares.

(4)  The Warrantholder is aware of the provisions of Rule 144, 
promulgated under the Act, which, in substance, permit limited 
public resale of restricted securities acquired, directly or 
indirectly, from the issuer thereof (or from an affiliate of such 
issuer), in a nonpublic offering subject to the satisfaction of 
certain conditions, if applicable, including, among other things: 
The availability of certain public information about the Company, 
the resale occurring not less than two years after the party has 
purchased and paid for the Securities to be sold; the sale being 
made through a broker in an unsolicited broker's transaction or in 
transactions directly with a market maker (as said term is defined 
under the Securities Exchange Act of 1934, as amended) and the 
amount of securities being sold during any three-month period not 
exceeding the specified limitations stated therein.

(5)  The Warrantholder further understands that it may not 
transfer the Warrants and that at the time it wishes to sell the 
Shares, it is possible that there will be no public market upon 
which to make such a sale, and that, even if such a public market 
then exists, the Company may not be satisfying the current public 
information requirements of Rule 144, and that, in such event, the 
Warrantholder may be precluded from selling the Shares under Rule 
144 even if the two-year minimum holding period had been 
satisfied.

(6)  The Warrantholder further understands that in the event all 
of the requirements of Rule 144 are not satisfied, registration 
under the Act, compliance with registration exemption will be 
required; and that, notwithstanding the fact that Rule 144 is not 
exclusive, the Staff of the SEC has expressed its opinion that 
persons proposing to sell private placement securities other than 
in a registered offering and otherwise than pursuant to Rule 144 
will have a substantial burden of proof in establishing that an 
exemption from registration is available for such offers or sales, 
and that such persons and their respective brokers who participate 
in such actions do so at their own risk.

(7)  To the Warrantholder's knowledge, the Warrantholder has 
received the Company's most recent Form 10-KSB, proxy statement 
and all Forms 10-QSB and Forms 8-K since the end of the Company's 
most recently completed fiscal year.  The Warrantholder has had a 
reasonable opportunity to ask questions relating to and otherwise 
discuss the terms and conditions of the offering and the other 
information set forth in the materials received from the Company 
and the Company's business, management and financial affairs with 
the Company's management, customers and other parties, and the 
Warrantholder has received satisfactory responses to the 
Warrantholder's inquiries.  Unless the Warrantholder has otherwise 
notified the Company in writing, the Warrantholder is not, and has 
not been within the ninety (90) days prior to the closing date of 
the purchase of the Securities, a broker or dealer of securities 
or an officer, director, employee, agent or affiliate of the 
Company or, to the Warrantholder's knowledge, any other purchaser 
of Securities from the Company.  Unless the Warrantholder has 
otherwise notified the Company in writing, the Warrantholder is 
not an employee, officer or director of the Company nor prior to 
the consummation of the actions contemplated hereby, is the 
Warrantholder the beneficial owner of 5% or more of the Common 
Stock of the Company.  To the best of its knowledge, (i) the 
Warrantholder was contacted regarding the sale of the Securities 
by a person or entity with whom the Warrantholder had a prior 
relationship and (ii) no securities were offered or sold to it by 
means of any form of general solicitation or general advertising, 
and in connection therewith the Warrantholder:  did not (A) 
receive or review any advertisement, article, notice or other 
communication published in a newspaper or magazine or similar 
media or broadcast over television or radio whether closed 
circuit, or generally available; or (B) attend any seminar meeting 
or industry investor conference whose attendees were invited by 
any general solicitation or general advertising.

(b)  Disposition of Shares.  With respect to any offer, sale or 
other disposition of any Shares that is not registered under the 
Act, the Warrantholder hereof agrees to give written notice to the 
Company prior thereto, describing briefly the manner thereof, 
together with a written opinion of such Warrantholder's counsel, 
if reasonably requested by the Company, to the effect that such 
offer, sale or other disposition may be effected without 
registration or qualification (under the Act as then in effect or 
any federal or state law then in effect) of such Securities and 
indicating whether or not under the Act, certificates for the 
Shares in question to be sold or otherwise disposed of require any 
restrictive legend as to applicable restrictions on 
transferability in order to ensure compliance with such law.  Such 
opinion must be satisfactory to the Company in its reasonable 
judgment and shall state that it may be relied upon by counsel to 
the Company, and any stock exchange or transfer agent.  Promptly 
upon receiving such written notice and satisfactory opinion, if so 
requested, the Company shall notify such Warrantholder that such 
Warrantholder may sell or otherwise dispose of such Shares all in 
accordance with the terms of the notice delivered to the Company.  
If a determination has been made pursuant to this subsection (b) 
that the opinion of counsel for the Warrantholder is not 
satisfactory to the Company, the Company shall so notify the 
Warrantholder promptly after such determination has been made and 
shall specify in detail the legal analysis supporting any such 
conclusion.  Each certificate representing the Shares thus 
transferred (except a transfer registered under the Act or a 
transfer of Shares pursuant to Rule 144) shall bear a legend as to 
the applicable restrictions on transferability in order to ensure 
compliance with such laws, unless in the aforesaid opinion of 
counsel for the Warrantholder, such legend is not required in 
order to ensure compliance with such laws.  The Company may issue 
stop transfer instructions to its transfer agent in connection 
with such restrictions.

(c)  Transferees Bound.  Prior to any transfer of the Shares 
(except a transfer registered under the Act or a transfer of 
Shares pursuant to Rule 144), the proposed transferee shall agree 
in writing with the Company to be bound by the terms of this 
Agreement (whether or not the Warrant has been exercised or 
otherwise outstanding) as if an original signatory hereto and the 
proposed transferee must be able to and must make representations 
as set forth in this Section 11.1.

(d)  As the Warrants are not transferrable, the Warrantholder is 
not entitled to any registration rights with respect to the 
transfer thereof.

Section 11.2  Certain Definitions.  As used in this Section 
11, the following terms shall have the following meanings:

Affiliate shall mean, with respect to any person, any other 
person controlling, controlled by or under direct or indirect 
common control with such person (for the purposes of this 
definition control, when used with respect to any specified 
person, shall mean the power to direct the management and policies 
of such person, directly or indirectly, whether through ownership 
of voting securities, by contract or otherwise; and the terms 
controlling and controlled shall have meanings correlative to the 
foregoing).

Business Day shall mean a day Monday through Friday on which 
banks are generally open for business in the State of Texas.

Holders shall mean the Warrantholders, and any person holding 
Registrable Securities to whom the registration rights under this 
Section 11 have been transferred in accordance with the terms 
hereof.

Person shall mean any person, individual, corporation, 
partnership, trust or other nongovernmental entity or any 
governmental agency, court, authority or other body (whether 
foreign, federal, state, local or otherwise).

Prior Holders shall mean the parties granted registration rights 
under the Stockholders' Agreement.

The terms register, registered and registration refer to the 
registration effected by preparing and filing a registration 
statement in compliance with the Act, and the declaration or 
ordering of the effectiveness of such registration statement.

Registrable Securities shall mean (A) the Shares, and (B) any 
shares of Common Stock issued as (or issuable upon the conversion 
of any warrant, right or other security which is issued as) a 
dividend or other distribution with respect to or in replacement 
of the Shares; provided, however, that securities shall only be 
treated as Registrable Securities if and only for so long as they 
(I) have not been disposed or pursuant to a registration statement 
declared effective by the SEC, (II) have not been sold in a 
transaction exempt from the registration and prospectus delivery 
requirements of the Act so that all transfer restrictions and 
restrictive legends with respect thereto are removed upon the 
consummation of such sale, (III) are held by a Holder or a 
permitted transferee pursuant to the terms hereof or (IV) held by 
a Holder as to which the registration rights of such Holder have 
not expired pursuant to Section 11.4(c).

Registration Expenses shall mean all expenses incurred by the 
Company in complying with Section 11.3 hereof, including, without 
limitation, all registration, qualification and filing fees, 
printing expenses, escrow fees, fees and expenses of counsel for 
the Company, blue sky fees and expenses (for a reasonable number 
of states) and the expense of any special audits incident to or 
required by any such registration (but excluding the fees of legal 
counsel for any Holder).

SEC shall mean the Securities and Exchange Commission or any other 
federal agency at the time administering the Act.

Selling Expenses shall mean all underwriting discounts and 
selling commissions applicable to the sale of Registrable 
Securities and all fees and expenses of legal counsel for any 
Holder.

Stockholders' Agreement shall mean the Amended and Restated 
Stockholders' Agreement among the Company and the parties thereto 
dated as of June 8, 1993, as amended as of April 29, 1994, and as 
it may be further amended from time to time, pursuant to which 
agreement, among other things, the Company granted registration 
rights to certain investors in the Company.

11.3  Piggy-Back Registration Rights.

(a)  Registration Rights.  Following the time of the exercise 
of a Warrant, the Holder of a Warrant Share thereby purchased 
shall be entitled to the piggy-back registration rights granted 
hereby.  These rights will commence 90 days after the Disbursement 
Date (as defined in the Purchase Agreement). If the Company shall 
determine to register any of its securities, either for its own 
account or the account of a security holder or holders, other than 
(i) a registration relating solely to employee benefit plans, or 
(ii) a registration relating solely to an SEC Rule 145 
transaction, the Company will:

(i)  promptly give to each Holder written notice thereof; and

(ii)  include in such registration (and any related qualification 
under blue sky laws or other compliance), all the Registrable 
Securities specified in a written request or requests, made within 
10 days after receipt of such written notice from the Company, by 
any Holder.

Such notification will be kept confidential by the Holder.  If the 
Holder desires to include in any such registration statement all 
or any part of the Registrable Securities held by him, the Holders 
shall, within ten (10) days after receipt of the above-described 
notice from the Company, so notify the Company in writing.  Such 
notice shall state the intended method of disposition of the 
Registrable Securities by such Holder.

(b)  Underwriting.  If the registration of which the Company 
gives notice is for a registered public offering involving an 
underwriting, the Company shall so advise the Holders as a part of 
the written notice given pursuant to Section 11.3(a)(i). In such 
event the right of any Holder to registration pursuant to Section 
11.3 shall be conditioned upon such Holder's participation in such 
underwriting, and the inclusion of Registrable Securities in the 
underwriting shall be limited to the extent provided herein.  All 
Holders proposing to distribute their securities through such 
underwriting shall (together with the Company and the other 
holders distributing their securities through such underwriting) 
enter into an underwriting agreement in customary form with the 
managing underwriter selected for such underwriting by the 
Company.  Notwithstanding any other provision of this Section 11, 
if the managing underwriter determines that marketing factors 
require a limitation of the number of shares to be underwritten, 
the underwriter may limit the Registrable Securities to be 
included in such registration.  In the event of a limitation (or 
elimination) on the number of shares to be included in a 
registration, then the Company shall so advise all Holders and the 
number of shares of Registrable Securities that may be included in 
the registration and underwriting shall be allocated among all 
Holders and all other persons holding registration rights in 
proportion, as nearly as practicable, to the respective number of 
shares of Common Stock held by the Holders and held by such other 
persons plus the number of shares of Common Stock into which other 
securities held by Holder and held by such other persons are 
convertible or exercisable, which are entitled to registration 
rights.  The parties hereto recognize that the ability of the 
underwriter to similarly limit the securities of the Prior Holders 
is limited to a reduction of not less than 25% of the number of 
shares to be registered in a registration initiated by the 
Company.  The Prior Holders shall have priority in order to first 
reach such 25% threshold.  To facilitate the allocation of shares 
in accordance with the above provisions, the Company may round the 
number of shares allocated to any Holder to the nearest 100 
shares.  If any Holder disapproves of the terms of any such 
underwriting, he may elect to withdraw therefrom by written notice 
to the Company and the managing underwriter.  Any securities 
excluded or withdrawn from such underwriting shall be withdrawn 
from such registration, and shall not be transferred in a public 
distribution prior to 120 days after the effective date of the 
registration statement relating thereto, or such other shorter 
period of time as the underwriters may require.  In the event of a 
registration initiated by the Prior Holders, the rights of the 
Holders are limited to that portion of such registration as 
remains after inclusion of all securities requested by such Prior 
Holders to be included in such registration.  

(c)  Representatives Warrants.  Notwithstanding anything to 
the contrary contained herein, the Holders shall have no rights to 
register any Registrable Securities pursuant to a registration 
initiated by the holders of the Representative's Warrants issued 
under the Representative's Warrant Agreement dated as of 
October 22, 1993 between the Company and H. J. Meyers & Co., Inc.

11.4  Registration Matters.

(a)  Right to Terminate Registration.  The Company or any 
other Person initiating registration shall have the right to 
terminate, suspend or withdraw any registration initiated by it 
under this Section 11 prior to or after the effectiveness of such 
registration whether or not any Holder has elected to include 
securities in such registration.  

(b)  Expenses of Registration.  All Registration Expenses 
incurred in connection with any registration, qualification or 
compliance pursuant to Section 11 shall be borne by the Company.  
All Selling Expenses relating to the sale of securities registered 
by or on behalf of Holders shall be borne by such Holders who 
directly incurred said expenses, except to the extent that the 
Holders may make separate arrangements for the sharing of 
expenses.

(c)  Registration Procedures.  In the case of the 
registration, qualification or compliance effected by the Company 
pursuant to this Agreement, the Company will, upon reasonable 
request, inform each Holder as to the status of such registration, 
qualification and compliance.  Subject to Section 11.4(a) above, 
at its expense the Company will:

(i)  use its reasonable best efforts to keep such registration, 
and any qualification or compliance under state securities laws 
which the Company determines to obtain, effective until at least 
the 90 days after the effective date of the registration or until 
the Holders have completed the distribution described in the 
registration statement relating thereto, whichever first occurs; 
and

(ii)  furnish such number of prospectuses and other documents 
incident thereto as the Holders from time to time may reasonably 
request.

Notwithstanding anything to the contrary contained herein, at the 
Company's election the Company may cease to keep such 
registration, qualification or compliance effective with respect 
to any Registrable Securities, and the registration rights of a 
Holder shall expire, at such time as the Holder may sell under 
Rule 144 under the Act (or other exemption from registration 
acceptable to the Company) in a three-month period all Registrable 
Securities then held by such Holder.  The period of time during 
which the Company is required hereunder to keep the Registration 
Statement effective is referred to herein as the Registration 
Period.

(d)  Delay of Registration.  The Holders shall have no right to 
take any action to restrain, enjoin or otherwise delay any 
registration pursuant to Section 11 hereof as a result of any 
controversy that may arise with respect to the interpretation or 
implementation of this Agreement.

(e)  Indemnification.

(i)  The Company will indemnify each Holder, each of its officers, 
directors, employees, partners, legal counsel and accountants, and 
each person controlling such Holder within the meaning of Section 
15 of the Act, with respect to which any registration, 
qualification or compliance has been effected pursuant to this 
Agreement, and each person who controls any underwriter within the 
meaning of Section 15 of the Act, against all expenses, claims, 
losses, damages and liabilities (or action in respect thereof), 
including any of the foregoing incurred in settlement of any 
litigation, commenced or threatened, arising out of or based on 
any untrue statement (or alleged untrue statement) of a material 
fact contained in any registration statement, prospectus, offering 
circular or other document, or any amendment or supplement 
thereof, incident to any such registration, qualification or 
compliance, or based on any omission (or alleged omission) to 
state therein a material fact required to be stated therein or 
necessary to make the statements therein not misleading, and will 
reimburse each Holder, each of its officers, directors, employees, 
partners, legal counsel and accountants, and each person 
controlling such Holder, and each person who controls any such 
underwriter, for reasonable legal and any other expenses 
reasonably incurred in connection with investigating, preparing or 
defending any such claim, loss, damage, liability or action as 
incurred, provided that the Company will not be liable in any such 
case to the extent that any untrue statement or omission or 
allegation thereof is made in reliance upon and in conformity with 
written information furnished to the Company by an instrument duly 
executed by or on behalf of such Holder and stated to be 
specifically for use in preparation of such registration 
statement, prospectus, offering circular or other document; and 
provided that the Company will not be liable in any such case 
where the expense, claim, loss, damage or liability arises out of 
or is related to the failure of the Holder to comply with the 
covenants and agreements contained in this Agreement respecting 
sales of Registrable Securities; and, provided, further, that the 
indemnity with respect to any preliminary prospectus shall not 
apply to the extent that any such claim, loss, damage or liability 
results from the fact that a current copy of the prospectus was 
not sent or given to the person asserting any such claims, losses, 
damages or liabilities at or prior to the written confirmation of 
the sale of the Registrable Securities confirmed to such person if 
such current copy of the prospectus would have cured the defect 
giving rise to such claim, loss, damage or liability.

(ii)  Each Holder will severally, if Registrable Securities held 
by such Holder are included in the securities as to which such 
registration, qualification or compliance is being effected, 
indemnify the Company, each of its directors, officers, employees, 
partners, legal counsel and accountants, each underwriter, if any, 
and each person who controls the Company or such underwriter 
within the meaning of Section 15 of the Act, against all claims, 
losses, damages and liabilities (or actions in respect thereof), 
including any of the foregoing incurred in settlement of any 
litigation, commenced or threatened, arising out of or based on 
any untrue statement (or alleged untrue statement) of a material 
fact contained in any registration statement, prospectus, offering 
circular or other document, or any amendment or supplement 
thereof, incident to any such registration, qualification or 
compliance, or based on any omission (or alleged omission) to 
state therein a material fact required to be stated therein or 
necessary to make the statements therein not misleading, or any 
failure by a Holder to comply with the covenants or agreements 
contained in this Agreement respecting the Registrable Securities 
and will reimburse the Company, such directors, officers, 
employees, partners, legal counsel and accountants for reasonable 
legal and any other expenses reasonably incurred in connection 
with investigating, preparing or defending any such claim, loss, 
damage, liability or action as incurred, in each case to the 
extent, but only to the extent, that such untrue statement or 
omission or allegation thereof is made in reliance upon and in 
conformity with written information furnished to the Company by an 
instrument duly executed by or on behalf of the Holder and stated 
to be specifically for use in preparation of such registration 
statement, prospectus, offering circular or other document; 
provided that the indemnity with respect to any preliminary 
prospectus shall not apply to the extent that such claim, loss, 
damage or liability results from the fact that a current copy of 
the prospectus was not sent or given to the person asserting any 
such claim, loss, damage or liability at or prior to the written 
confirmation of the sale of the Registrable Securities confirmed 
to such person if such current copy of the prospectus would have 
cured the defect giving rise to such loss, claim, damage or 
liability.  Notwithstanding the foregoing, in no event shall a 
Holder be liable for any such claims, losses, damages or 
liabilities in excess of the proceeds received by such Holder in 
the offering, except in the event of fraud by such Holder.  
(iii)  Each party entitled to indemnification under this 
subsection 11.4(e) (the Indemnified Party) shall give notice to 
the party required to provide indemnification (the Indemnifying 
Party) promptly after such Indemnified Party has actual knowledge 
of any claim as to which indemnity may be sought, and shall permit 
the Indemnifying Party to assume the defense of any such claim or 
any litigation resulting therefrom, provided that counsel for the 
Indemnifying Party, which shall conduct the defense of such claim 
or litigation, shall be approved by the Indemnified Party (whose 
approval shall not unreasonably be withheld), and the Indemnified 
Party may participate in such defense at such party's expense, and 
provided further that the failure of any Indemnified Party to give 
notice as provided herein shall not relieve the Indemnifying Party 
of its obligations under this Agreement, unless such failure is 
prejudicial to the Indemnifying Party in defending such claim or 
litigation.  An Indemnifying Party shall not be liable for any 
settlement of an action or claim effected without its written 
consent (which consent will not be unreasonably withheld).

(iv)  If the indemnification provided for in this subsection 
11.4(e) is held by a court of competent jurisdiction to be 
unavailable to an Indemnified Party with respect to any loss, 
liability, claim, damage or expense referred to therein, then the 
Indemnifying Party, in lieu of indemnifying such Indemnified Party 
thereunder, shall contribute to the amount paid or payable by such 
Indemnified Party as a result of such loss, liability, claim, 
damage or expense (i) in such proportion as is appropriate to 
reflect the relative benefits received by the Company on the one 
hand and all Holders offering shares in the offering (the Selling 
Shareholders) on the other from the offering of the Company 
securities, or (ii) if the allocation provided by clause (i) above 
is not permitted by applicable law, in such proportion as is 
appropriate to reflect not only the relative benefits referred to 
in clause (i) above but also the relative fault of the Company on 
the one hand and the Selling Shareholders on the other in 
connection with the statements or omissions which resulted in such 
losses, claims, damages or liabilities, as well as any other 
relevant equitable considerations.  The relative benefits received 
by the Company on the one hand, and the Selling Shareholders on 
the other shall be the net proceeds from the offering (before 
deducting expenses) received by the Company on the one hand and 
the Selling Shareholders on the other.  The relative fault of the 
Company on the one hand and the Selling Shareholders on the other 
shall be determined by reference to, among other things, whether 
the untrue or alleged untrue statement of material fact or the 
omission or alleged omission to state a material fact relates to 
information supplied by the Company on the one hand and/or the 
Selling Shareholders and the parties' relevant intent, knowledge, 
access to information and opportunity to correct or prevent such 
statement or omission.  The Company and the Selling Shareholders 
agree that it would not be just and equitable if contribution 
pursuant to this subsection 11.4(e) were based solely upon the 
number of entities from whom contribution was requested or by any 
other method of allocation which does not take account of the 
equitable considerations referred to above in this subsection 
11.4(e).

(f)  Covenants of Holders.

(i)  Each Holder agrees that, upon receipt of any notice from the 
Company of the happening of any event requiring the preparation of 
a supplement or amendment to a prospectus relating to Registrable 
Securities so that, as thereafter delivered to the Holders, such 
prospectus will not contain an untrue statement of a material fact 
or omit to state any material fact required to be stated therein 
or necessary to make the statements therein not misleading, each 
Holder will forthwith discontinue disposition of Registrable 
Securities pursuant to the registration statement contemplated by 
subsection 11.3 until its receipt of copies of the supplemented or 
amended prospectus from the Company and, if so directed by the 
Company, each Holder shall deliver to the Company all copies, 
other than permanent file copies then in such Holder's possession, 
of the prospectus covering such Registrable Securities current at 
the time of receipt of such notice.

(ii)  Each Holder agrees to suspend, upon request of the Company, 
any disposition of Registrable Securities pursuant to the 
registration statement and prospectus contemplated by 
subsection 11.3 during (A) any period not to exceed two 30-day 
periods within any one 12-month period the Company requires in 
connection with a primary underwritten offering of equity 
securities and (B) any period, not to exceed one 30-day period per 
circumstance or development, when the Company determines in good 
faith that offers and sales pursuant thereto should not be made by 
reason of the presence of material, undisclosed circumstances or 
developments with respect to which the disclosure that would be 
required in such a prospectus is premature, would have an adverse 
effect on the Company or is otherwise inadvisable.

(iii)  Each Holder agrees to notify the Company, at any time when 
a prospectus relating to the registration statement contemplated 
by subsection 11.3 is required to be delivered by it under the 
Act, of the occurrence of any event relating to the Holder which 
requires the preparation of a supplement or amendment to such 
prospectus so that, as thereafter delivered to the purchasers of 
Registrable Securities, such prospectus will not contain an untrue 
statement of a material fact or omit to state any material fact 
required to be stated therein or necessary to make the statements 
therein not misleading relating to the Holder, and each Holder 
shall promptly make available to the Company the information to 
enable the Company to prepare any such supplement or amendment. 
Each Holder also agrees that, upon delivery of any notice by it to 
the Company of the happening of any event of the kind described in 
the next preceding sentence of this subsection, the Holder will 
forthwith discontinue disposition of Registrable Securities 
pursuant to such registration statement until its receipt of the 
copies of the supplemental or amended prospectus contemplated by 
this subsection, which the Company shall promptly make available 
to each Holder and, if so directed by the Company, each Holder 
shall deliver to the Company all copies, other than permanent file 
copies then in such Holder's possession, of the prospectus 
covering such Registrable Securities current at the time of 
receipt of such notice.

(iv)  Each Holder shall furnish to the Company such information 
regarding such Holder and the distribution proposed by such Holder 
as the Company may request in writing or as shall be required in 
connection with any registration, qualification or compliance 
referred to in this Section 11.

(v)  Each Holder hereby covenants with the Company (1) not to make 
any sale of the Shares without effectively causing the prospectus 
delivery requirements under the Act to be satisfied, and (2) if 
such Shares are to be sold by any method or in any transaction 
other than on the AMEX (or other national securities exchange), in 
the over-the-counter market, on the NASDAQ National Market, in 
privately negotiated transactions, or in a combination of such 
methods, to notify the Company at least five business days prior 
to the date on which the Holder first offers to sell any such 
Shares.

(vi)  Each Holder acknowledges and agrees that the Registrable 
Securities sold pursuant to the registration statement described 
in this Section are not transferable on the books of the Company 
unless the stock certificate submitted to the transfer agent 
evidencing such Shares is accompanied by a certificate reasonably 
satisfactory to the Company to the effect that (A) the Registrable 
Securities have been sold in accordance with such registration 
statement and (B) the requirement of delivering a current 
prospectus has been satisfied.

(vii)  During the time a registration statement contemplated by 
Section 11.3 is effective, each Holder agrees that it will not 
effect any disposition of the Registrable Securities that would 
constitute a sale within the meaning of the Act except pursuant to 
such registration statement. Each Holder agrees not to take any 
action with respect to any distribution deemed to be made pursuant 
to such registration statement, that constitutes a violation of 
Rule 10(b)-6 under the Exchange Act or any other applicable rule, 
regulation or law.

(g)  Rule 144 Reporting.  With a view to making available to 
the Holders the benefits of certain rules and regulations of the 
SEC which at any time permit the sale of the Registrable 
Securities to the public without registration, the Company agrees 
to use its reasonable best efforts to:

(i)  make and keep public information available, as those terms 
are understood and defined in Rule 144 under the Act, at all 
times;

(ii)  file with the SEC in a timely manner all reports and other 
documents required of the Company under the Exchange Act; and 

(iii)  so long as a Holder owns any unregistered Registrable 
Securities, furnish to such Holder upon any reasonable request a 
written statement by the Company as to its compliance with 
Rule 144 under the Act, and of the Exchange Act, a copy of the 
most recent annual or quarterly report of the Company, and such 
other reports and documents of the Company as such Holder may 
reasonably request in availing itself of any rule or regulation of 
the SEC allowing a Holder to sell any such securities without 
registration.

(h)  Transfer of Registration Rights.  The rights to cause 
the Company to include Registrable Securities in a Registration 
Statement granted to the Holders by the Company under Section 11.3 
may be assigned in full by a Holder to an Affiliate of such 
Holder; provided, that: (i) such transfer may otherwise be 
effected in accordance with applicable securities laws; (ii) such 
Holder gives prior written notice to the Company; and (iii) such 
transferee agrees to comply with the terms and provisions of this 
Agreement and such transfer is otherwise in compliance with this 
Agreement.  Except as specifically permitted by this 
paragraph (h), the rights of a Holder with respect to Registrable 
Securities as set out herein shall not be transferable to any 
other Person, and any attempted transfer shall cause all rights of 
such Holder therein to be forfeited.  

(i)  Waivers and Amendments.  With the written consent of the 
Company and the Holders holding at least a majority of the then 
outstanding Registrable Securities, any provision of Section 11.3 
and 11.4 may be waived (either generally or in a particular 
instance, either retroactively or prospectively and either for a 
specified period of time or indefinitely) or amended.  Upon the 
effectuation of each such waiver or amendment, the Company shall 
promptly give written notice thereof to the Holders, if any, who 
have not previously received notice thereof or consented thereto 
in writing.

Section 12.  Notices.  Any notice pursuant to this Agreement by 
the Company or by a Warrantholder or a holder of Shares shall be 
in writing and shall be deemed to have been duly given if 
delivered or mailed by certified mail, return receipt requested:

(a)  If to the Warrantholder or a holder of Shares addressed to it 
at the address set forth in Schedule 1.

(b)  If to the Company addressed to it at 8000 El Rio Street, 
Houston, Texas 77054, Attention:  Vice President-Finance.

Each party may from time to time change the address to which 
notices to it are to be delivered or mailed hereunder by notice in 
accordance herewith to the other party.

Section 13.  Successors.  All the covenants and provisions of 
this Agreement by or for the benefit of the Company, the 
Warrantholder or the holders of Shares shall bind and inure to the 
benefit of their respective successors and assigns hereunder.

Section 14.  Applicable Law.  This Agreement shall be 
deemed to be a contract made under the laws of the State 
of New York and for all purposes shall be construed in 
accordance with the laws of said State.

Section 15.  Benefits of this Agreement.  Nothing in this 
Agreement shall be construed to give to any person or corporation 
other than the Company, the Warrantholder and the holders of 
Shares any legal or equitable right, remedy or claim under this 
Agreement.  This Agreement shall be for the sole and exclusive 
benefit of the Company, the Warrantholder and the holders of 
Shares. 

Section 16.  Counterparts.  This Agreement may be executed in 
any number of counterparts each of which shall be deemed an 
original, but all of which shall constitute one and the same 
instrument.

Section 17.  Amendment.  Except as expressly provided herein, 
neither this Agreement nor any term hereof may be amended, waived, 
discharged or terminated other than by a written instrument signed 
by the party against whom enforcement of any such amendment, 
waiver, discharge or termination is sought; provided, however, 
that any provisions hereof may be amended, waived, discharged or 
terminated upon the written consent of the Company and the then 
current Warrantholders having the right to acquire by virtue of 
holding the Warrants at least 50% of the Shares which are then 
issuable upon exercise of the then outstanding Warrants.

IN WITNESS WHEREOF, the parties have caused this Agreement to be 
duly executed, all as of the day and year first above written.

	APROGENEX, INC.



	By: 					
	Name:  J. Donald Payne
	Title:  Vice President - Finance



	WARRANTHOLDER:



	By: 					
	Name:  					
	Title:  					

Exhibit A

THE WARRANTS REPRESENTED BY THIS CERTIFICATE HAVE BEEN ACQUIRED 
FOR INVESTMENT AND HAVE NOT BEEN REGISTERED UNDER THE SECURITIES 
ACT OF 1933, AS AMENDED, OR ANY STATE SECURITIES LAW.  SUCH 
WARRANTS ARE NOT TRANSFERRABLE AND ANY ATTEMPTED TRANSFER SHALL BE 
VOID AND NOT RECOGNIZED BY THE COMPANY. COPIES OF THE WARRANT 
AGREEMENT AND THE PURCHASE AGREEMENT COVERING THE PURCHASE OF 
THESE WARRANTS AND VARIOUS REQUIREMENTS, INCLUDING WITHOUT 
LIMITATION PROVISIONS PROHIBITING THEIR TRANSFER, MAY BE OBTAINED 
AT NO COST BY WRITTEN REQUEST MADE BY THE HOLDER OF RECORD OF THIS 
CERTIFICATE TO THE SECRETARY OF THE CORPORATION AT THE PRINCIPAL 
EXECUTIVE OFFICES OF THE CORPORATION.

	Warrant Certificate 
No. WC-__

WARRANTS TO PURCHASE ______________ SHARES OF COMMON STOCK

APROGENEX, INC.

INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE

This certifies that, for value received, ___________, the 
registered holder hereof (the Warrantholder), is entitled to 
purchase from APROGENEX, INC. (the Company), at any time during 
the period commencing after both (i) the date hereof and (ii) the 
American Stock Exchange's approval of the listing of the Shares 
(as defined herein), and ending at 5:00 p.m., Houston, Texas Time, 
on May 28, 1999 at a purchase price per share of [$____], the 
number of shares of Common Stock of the Company set forth above 
(the Shares).  The number of shares of Common Stock of the Company 
purchasable upon exercise of each Warrant evidenced hereby shall 
be subject to adjustment from time to time as set forth in the 
Warrant Agreement.

The Warrants evidenced hereby may be exercised in whole or in part 
by presentation of this Warrant Certificate with the Purchase Form 
attached hereto duly executed (with a signature guarantee as 
provided thereon) and simultaneous payment of the Warrant Price at 
the principal office of the Company.  Payment of such price shall 
be made in immediately available funds.

The Warrants evidenced hereby represent the right to purchase an 
aggregate of up to [__________] Shares and are issued under and in 
accordance with a Warrant Agreement, dated as of May 1, 1996 (the 
Warrant Agreement), between the Company and certain Warrantholders 
(which Warrant Agreement initially provides for Warrants to 
purchase up to [_________] shares) and are subject to the terms 
and provisions contained in the Warrant Agreement, to all of which 
the Warrantholder by acceptance hereof consents.

Upon any partial exercise of the Warrants evidenced hereby, there 
shall be signed and issued to the Warrantholder a new Warrant 
Certificate in respect of the Shares as to which the Warrants 
evidenced hereby shall not have been exercised.  These Warrants 
may be exchanged at the office of the Company by surrender of this 
Warrant Certificate properly endorsed for one or more new Warrants 
of the same aggregate number of Shares as here evidenced by the 
Warrant or Warrants exchanged.  No fractional shares of Common 
Stock will be issued upon the exercise of rights to purchase 
hereunder, but the Company shall pay the cash value of any 
fraction upon the exercise of one or more Warrants.  These 
Warrants are not transferrable and any attempted transfer shall be 
void.

This Warrant Certificate does not entitle any Warrantholder to any 
of the rights of a stockholder of the Company.

	APROGENEX, INC.


	By: 						
		David Leech
		President and Chief Executive 
Officer
	Dated:  __________ ___, 1996
ATTEST:


By:							
	J. Donald Payne
	Secretary

APROGENEX, INC.
PURCHASE FORM

APROGENEX, INC.
8000 El Rio Street
Houston, Texas  77054

The undersigned hereby irrevocably elects to exercise the right of 
purchase represented by the within Warrant Certificate for, and to 
purchase thereunder, ______+__ shares of Common Stock (the Shares) 
provided for therein, and requests that certificates for the 
Shares be issued in the name of:

										
(Please Print or Type Name, Address and Social Security Number)

										

										

and, if said number of Shares shall not be all the Shares 
purchasable hereunder, that a new Warrant Certificate for the 
balance of the Shares purchasable under the within Warrant 
Certificate be registered in the name of the undersigned 
Warrantholder or his Assignee as below indicated and delivered to 
the address stated below.  The undersigned has also submitted to 
the Company a certificate in which it has made the representations 
and covenants required in Section 11 of the Warrant Agreement.

Dated:  				

Name of Warrantholder
or Assignee:  					
		(Please Print)

Address:  					

						

Signature:  					

Note:  The above signature must correspond with the name as 
written upon the face of this Warrant Certificate in every 
particular, without alteration or enlargement or any change 
whatever, unless these Warrants have been assigned.

Signature Guaranteed:  						

(Signature must be guaranteed by a bank or trust company having an 
office or correspondent in the United States or by a member firm 
of a registered securities exchange or the National Association of 
Securities Dealers, Inc.)


SCHEDULE 1

SCHEDULE OF WARRANTHOLDERS

NOT INCLUDED






Exhibit 99.1

Contact:	Company:
	J. Donald Payne
	Vice President - Finance
	Aprogenex, Inc.
	713/748-5114


APROGENEX CLOSES OFFERING OF SECURITIES

	HOUSTON, TX, JUNE 13, 1996 -- Aprogenex, Inc. (AMEX: APG) 
today announced that it has closed an offering of convertible 
notes and warrants with gross proceeds of approximately $2 
million.  The Company stated that the funds available from the 
offering should fund the Company's normal operating activities 
through the end of 1996.  The terms of the offering were not 
disclosed.

	The securities offered were not registered under the 
Securities Act of 1933, as amended, and may not be offered or sold 
in the United States absent registration or an applicable 
exemption from registration requirements.  


________________________________________________________________
The statements in this news release that are not historical facts 
are forward-looking statements and are subject to a wide range of 
risks and uncertainties, including but not limited to risks and 
uncertainties relating to product development activities; new or 
developing markets; limited marketing experience; need for 
additional financing; government regulation; licenses, patents and 
trade secrets; potential adverse effects of technological change 
and competition; dependence on key personnel; possibility of 
product liability claims; and other factors detailed in the 
Company's Securities and Exchange Commission filings.

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