OPTICAL SENSORS INC
DEF 14A, 1997-04-04
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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<PAGE>
 
                           SCHEDULE 14A INFORMATION

                  PROXY STATEMENT PURSUANT TO SECTION 14(a) 
                    OF THE SECURITIES EXCHANGE ACT OF 1934 
        
                Filed by the Registrant [X]
                Filed by a Party other than the Registrant [_] 

Check the appropriate box:

[ ]  Preliminary Proxy Statement        
[ ]  Confidential, for Use of the Commission Only (as permitted by 
     Rule 14a-6(e)(2))
[X]  Definitive Proxy Statement 
[ ]  Definitive Additional Materials 
[ ]  Soliciting Material Pursuant to 240.14a-11(c) or 240.14a-12

                         Optical Sensors Incorporated
           ---------------------------------------------------------
               (Name of Registrant as Specified in its Charter)


   -------------------------------------------------------------------------
   (Name of Person(s) Filing Proxy Statement, if Other than the Registrant)

   
Payment of Filing Fee (Check the appropriate box):

[X]  No fee required.
[ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

     (1) Title of each class of securities to which transaction applies:

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     (2) Aggregate number of securities to which transaction applies:

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     (3) Per unit price or other underlying value of transaction computed
         pursuant to Exchange Act Rule 0-11 (Set forth the amount on which
         the filing fee is calculated and state how it was determined):

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     (4) Proposed maximum aggregate value of transaction:

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     (5) Total fee paid:

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[ ]  Fee paid previously with preliminary materials.
[ ]  Check box if any part of the fee is offset as provided by Exchange
     Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee
     was paid previously. Identify the previous filing by registration statement
     number, or the Form or Schedule and the date of its filing.
     
     (1) Amount Previously Paid:
 
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     (2) Form, Schedule or Registration Statement No.:

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     (4) Date Filed:

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<PAGE>
 
                         OPTICAL SENSORS INCORPORATED
                      7615 GOLDEN TRIANGLE DRIVE, SUITE A
                         MINNEAPOLIS, MINNESOTA 55344
 
TO THE STOCKHOLDERS OF OPTICAL SENSORS INCORPORATED:
 
  You are cordially invited to attend our Annual Meeting of Stockholders to be
held on May 13, 1997, at 3:30 p.m., local time, at the Marquette Hotel, 710
Marquette Avenue, Minneapolis, Minnesota.
 
  The formal Notice of Meeting, Proxy Statement and form of proxy are
enclosed.
 
  Whether or not you plan to attend the meeting, please date, sign and return
the enclosed proxy in the envelope provided as soon as possible so that your
vote will be recorded.
 
                                          Very truly yours,
 
                                          LOGO
 
                                          Sam B. Humphries
                                          President and Chief Executive
                                          Officer
 
April 4, 1997
 
                         PLEASE SIGN, DATE AND RETURN
                          THE ENCLOSED PROXY PROMPTLY
                        TO SAVE THE COMPANY THE EXPENSE
                          OF ADDITIONAL SOLICITATION.
<PAGE>
 
                         OPTICAL SENSORS INCORPORATED
                      7615 GOLDEN TRIANGLE DRIVE, SUITE A
                         MINNEAPOLIS, MINNESOTA 55344
 
                               ----------------
 
                   NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                            TO BE HELD MAY 13, 1997
 
                               ----------------
 
TO THE STOCKHOLDERS OF OPTICAL SENSORS INCORPORATED:
 
  Notice is hereby given that the Annual Meeting of Stockholders of Optical
Sensors Incorporated, a Delaware corporation (the "Company"), will be held on
Tuesday, May 13, 1997, at 3:30 p.m., local time, at the Marquette Hotel, 710
Marquette Avenue, Minneapolis, Minnesota, for the following purposes:
 
  1. To elect six (6) persons to serve as directors until the next annual
     meeting of stockholders or until their respective successors shall be
     elected and qualified.
 
  2. To consider and act upon a proposal to approve the Company's Employee
     Stock Purchase Plan.
 
  3. To ratify the appointment of Ernst & Young LLP, certified public
     accountants, as independent auditors for the Company for the fiscal year
     ending December 31, 1997.
 
  4. To consider and act upon such other matters as may properly come before
     the meeting or any adjournment thereof.
 
  Only stockholders of record at the close of business on March 20, 1997 will
be entitled to notice of, and to vote at, the meeting and any adjournments
thereof.
 
                                          By Order of the Board of Directors,
 
                                          LOGO
 
                                          Wesley G. Peterson
                                          Secretary
 
April 4, 1997
Minneapolis, Minnesota
 
   YOU ARE CORDIALLY INVITED TO ATTEND THE ANNUAL MEETING. NO ADMISSION
 TICKET OR OTHER CREDENTIALS WILL BE NECESSARY. IF YOU DO NOT PLAN TO ATTEND
 THE MEETING, PLEASE BE SURE YOU ARE REPRESENTED AT THE MEETING BY MARKING,
 SIGNING, DATING AND MAILING YOUR PROXY IN THE REPLY ENVELOPE PROVIDED.
 
<PAGE>
 
                         OPTICAL SENSORS INCORPORATED
                      7615 GOLDEN TRIANGLE DRIVE, SUITE A
                         MINNEAPOLIS, MINNESOTA 55344
 
                               ----------------
 
                                PROXY STATEMENT
                                      FOR
                        ANNUAL MEETING OF STOCKHOLDERS
 
                                 MAY 13, 1997
 
                               ----------------
 
                                 INTRODUCTION
 
  The Annual Meeting of Stockholders of Optical Sensors Incorporated (the
"Company") will be held on Tuesday, May 13, 1997, at 3:30 p.m., local time, at
the Marquette Hotel, 710 Marquette Avenue, Minneapolis, Minnesota, or at any
adjournment or adjournments thereof (the "Annual Meeting"), for the purposes
set forth in the Notice of Meeting.
 
  A proxy card is enclosed for your use. You are solicited on behalf of the
Board of Directors to SIGN AND RETURN THE PROXY CARD IN THE ACCOMPANYING
ENVELOPE. No postage is required if mailed within the United States. The cost
of soliciting proxies, including the preparation, assembly and mailing of
proxies and soliciting material, as well as the cost of forwarding such
material to the beneficial owners of the Company's common stock, $.01 par
value (the "Common Stock") will be borne by the Company. Directors, officers
and regular employees of the Company may, without compensation other than
their regular compensation, solicit proxies by telephone, telegraph or
personal conversation. The Company may reimburse brokerage firms and others
for expenses in forwarding proxy materials to the beneficial owners of the
Common Stock.
 
  Any stockholder giving a proxy may revoke it at any time prior to its use at
the Annual Meeting either by giving written notice of such revocation to the
Secretary of the Company, by filing a duly executed proxy bearing a later date
with the Secretary of the Company, or by appearing at the Annual Meeting and
filing written notice of revocation with the Secretary of the Company prior to
use of the proxy. Proxies will be voted as specified by stockholders. Proxies
that are signed by stockholders but that lack any such specification will be
voted in favor of the proposals set forth in the Notice of Meeting and in
favor of the election as directors of the nominees for directors listed in
this Proxy Statement.
 
  THE BOARD RECOMMENDS THAT THE STOCKHOLDERS VOTE FOR THE APPROVAL OF THE
PROPOSALS SET FORTH IN THE NOTICE OF MEETING.
 
  The Company expects that this proxy material will first be mailed to
stockholders on or about April 4, 1997.
 
                               VOTING OF SHARES
 
  Only holders of the Common Stock of record at the close of business on March
20, 1997 will be entitled to vote at the Annual Meeting. On March 20, 1997,
the Company had 8,349,279 outstanding shares of Common Stock, each such share
entitling the holder thereof to one vote on each matter to be voted on at the
Annual Meeting.
 
  The presence at the Annual Meeting, in person or by proxy, of the holders of
a majority of the outstanding shares of Common Stock entitled to vote at the
Annual Meeting (4,174,640 shares) will
<PAGE>
 
constitute a quorum for the transaction of business at the Annual Meeting. In
general, shares of Common Stock represented by a properly signed and returned
proxy card will be counted as shares present and entitled to vote at the
Annual Meeting for purposes of determining a quorum, without regard to whether
the card reflects abstentions (or is left blank) or reflects a "broker non-
vote" on a matter (i.e., a card returned by a broker on behalf of its
beneficial owner customer that is not voted on a particular matter because
voting instructions have not been received and the broker has no discretionary
authority to vote).
 
  Holders of shares of Common Stock are not entitled to cumulate voting
rights.
 
  The election of a nominee for director requires the approval of a plurality
of the shares present and entitled to vote in person or by proxy and the
approval of the other proposals described in this Proxy Statement requires the
approval of a majority of the shares present and entitled to vote in person or
by proxy on that matter (and at least a majority of the minimum number of
votes necessary for a quorum to transact business at the Annual Meeting).
Shares represented by a proxy card including any broker non-votes on a matter
will be treated as shares not entitled to vote on that matter, and thus will
not be counted in determining whether that matter has been approved. Shares
represented by a proxy card voted as abstaining on any of the proposals will
be treated as shares present and entitled to vote that were not cast in favor
of a particular matter, and thus will be counted as votes against that matter.
 
                             ELECTION OF DIRECTORS
 
                                  PROPOSAL 1
 
NOMINATION
 
  The Bylaws of the Company provide that the number of directors must be at
least one or such other number as shall be fixed from time to time by
resolution of the Board of Directors. The Board of Directors of the Company
(the "Board") has set its size at six and has nominated the six individuals
named below to serve as directors of the Company until the next annual meeting
of stockholders or until their respective successors have been elected and
qualified. All of the nominees are current members of the Board.
 
  Assuming a quorum is represented at the Annual Meeting, either in person or
by proxy, the election of each director requires the affirmative vote of a
plurality of the shares of Common Stock represented in person or by proxy at
the Annual Meeting. The Board recommends a vote FOR the election of each of
the nominees listed below. In absence of other instructions, the proxies will
be voted FOR the election of each of the nominees named below. If prior to the
Annual Meeting the Board should learn that any nominee will be unable to serve
by reason of death, incapacity or other unexpected occurrence, the proxies
that otherwise would have been voted for such nominee will be voted for such
substitute nominee as selected by the Board. Alternatively, the proxies, at
the Board's discretion, may be voted for such fewer number of nominees as
results from such death, incapacity or other unexpected occurrence. The Board
has no reason to believe that any of the nominees will be unable to serve.
 
                                       2
<PAGE>
 
INFORMATION ABOUT NOMINEES
 
  The following table sets forth certain information as of February 1, 1997,
which has been furnished to the Company by each of the persons who has been
nominated by the Board to serve as directors for the ensuing year.
 
<TABLE>
<CAPTION>
                                                                               DIRECTOR
NAME OF NOMINEE           AGE               PRINCIPAL OCCUPATION                SINCE
- ---------------           ---               --------------------               --------
<S>                       <C> <C>                                              <C>
Sam B. Humphries........   54 President and Chief Executive Officer of the       1991
                               Company
Promod Haque, Ph.D. (1).   48 Vice President and General Partner of Norwest      1992
                               Venture Capital
Peter H. McNerney (1)...   46 Executive Vice President of Coral Group, Inc.      1993
John M. Nehra (2).......   48 General Partner of New Enterprise Associates VI,   1992
                               L.P. and Managing General Partner of Catalyst
                               Ventures
Demetre M. Nicoloff,       63 Cardiac Surgeon and Senior Partner of Cardiac      1989
 M.D....................       Surgical Associates
Gary A. Peterson (2)....   45 President of Peterson-Spencer-Fansler Company      1990
</TABLE>
- --------
(1) Member of the Audit Committee
(2) Member of the Compensation Committee
 
OTHER INFORMATION ABOUT NOMINEES
 
  SAM B. HUMPHRIES has been the President, Chief Executive Officer and a
Director of the Company since October 1991. From January 1988 to October 1991,
he served as President and Chief Executive Officer of American Medical
Systems, a medical device manufacturer which is a subsidiary of Pfizer, Inc.
Mr. Humphries also served as a member of the Board of Directors of the
Hospital Products Group at Pfizer, Inc. Mr. Humphries is a Director of
Universal Hospital Services, Inc.
 
  PROMOD HAQUE, PH.D. has served as a Director of the Company since April
1992. Dr. Haque was initially elected to the Board in connection with the
purchase by Norwest Equity Partners IV of stock of the Company as required by
the purchase agreement under which such shares of stock were issued. This
requirement has expired. Since 1989, Dr. Haque has been employed by Norwest
Venture Capital, a venture capital firm, and currently serves as its Vice
President and General Partner. Prior to joining Norwest, Dr. Haque had over 18
years experience in management, sales, product development and marketing with
various companies including Siemens Medical Inc., Thorn-EMI, Emergent
Corporation and Dimensional Medicine, Inc. Dr. Haque currently serves as a
Director of Connect, Inc., Raster Graphics, Inc., Forte Software, Inc., Prism
Solutions, Inc., Transaction Systems Architects, Inc., Tivoli Systems, Inc.
and several privately held companies.
 
  PETER H. MCNERNEY has been a Director of the Company since June 1993. Mr.
McNerney was initially elected to the Board in connection with the purchase by
Coral Partners II of stock of the Company as required by the purchase
agreement under which such shares of stock were issued. This requirement has
expired. Since July 1992, Mr. McNerney has been a General Partner of the
General Partner of Coral Partners II. Mr. McNerney is the Executive Vice
President of Coral Group, Inc., a manager of venture capital partnerships.
From 1989 through June 1992, Mr. McNerney was the Managing Partner and a
founder of The Kensington Group, a provider of management services to health
care companies. Mr. McNerney currently serves as a Director of Aksys, Ltd.,
Biomira, Inc. and Cerus Corporation.
 
                                       3
<PAGE>
 
  JOHN M. NEHRA has been a Director of the Company since April 1992. Mr. Nehra
was initially elected to the Board in connection with the purchase by Catalyst
Ventures Limited Partnership and New Enterprise Associates V Limited
Partnership of stock of the Company as required by the purchase agreement
under which such shares of stock were issued. This requirement has expired.
Since December 1993, Mr. Nehra has been a general partner of New Enterprise
Associates VI, L.P., a venture capital firm, and since 1989, Mr. Nehra has
been the Managing General Partner of Catalyst Ventures Limited Partnership, a
venture capital firm. From 1983 to 1989, Mr. Nehra was a Managing Director of
Alex. Brown & Sons Incorporated, an investment banking firm, and was
responsible for its Capital Markets Group, including health care corporate
finance. Mr. Nehra is also a Director of VIVRA Incorporated, Summit Medical
Systems, Inc. and Iridex Corporation.
 
  DEMETRE NICOLOFF, M.D. has been a Director of the Company since July 1989.
Dr. Nicoloff has been a cardiac surgeon for more than 15 years, and is
presently a Senior Partner of Cardiac Surgical Associates with practices at
the Minneapolis Heart Institute and the St. Paul Heart and Lung Institute. Dr.
Nicoloff is a member of the Board of Directors of Possis Medical, Inc. and
Applied Biometrics Inc.
 
  GARY A. PETERSON has been a Director of the Company since June 1990. Mr.
Peterson has been the President of Peterson-Spencer-Fansler Company, a capital
sourcing and operational consulting company since 1991. Mr. Peterson is also a
General Partner of PSF Advisors, the General Partner of PSF Health Care Fund
L.P., a venture capital limited partnership, and President and Chief Executive
Officer of BATON Development, Inc., a virtual incubator for medical products.
He was also President of Peterson-Spencer-Fansler Investments, Inc., a
registered broker-dealer and a registered investment advisor. From 1986
through 1994, Mr. Peterson served as President of Genesis Venture Development,
Inc., a venture capital fund management company. Mr. Peterson was a founder of
Angiomedics Incorporated and served in the capacities of Chief Operating
Officer and Executive Vice President from its inception in 1983 to 1986 at
which time Angiomedics was acquired by Pfizer, Inc. Mr. Peterson continues to
be a director of numerous medical product and health care service companies.
 
INFORMATION ABOUT THE BOARD AND ITS COMMITTEES
 
  The Board of Directors met six times during 1996. All of the Directors
attended 75% or more of the meetings of the Board and all such committees on
which they served during 1996.
 
  The Board has established an Audit Committee and a Compensation Committee.
The Audit Committee provides assistance to the Board in satisfying its
fiduciary responsibilities relating to accounting, auditing, operating and
reporting practices of the Company, and reviews the annual financial
statements of the Company, the selection and work of the Company's independent
auditors and the adequacy of internal controls for compliance with corporate
policies and directives. The Audit Committee consists of Dr. Haque and Mr.
McNerney, and it met one time during fiscal 1996.
 
  The Compensation Committee makes recommendations to the Board of Directors
concerning the compensation of the Company's directors, executive officers and
key managers, and acts on such other matters relating to their compensation as
it deems appropriate. In addition, the Compensation Committee administers the
Company's stock option plans, pursuant to which incentive stock options and
non-statutory stock options may be granted to eligible key employees,
officers, directors and consultants of the Company. It is also intended that
the Compensation Committee will administer the Company's Employee Stock
Purchase Plan. The Compensation Committee consists of Mr. Nehra and Mr.
Peterson, and it met one time during fiscal 1996. See "Executive Compensation
and Other Benefits--Compensation Committee Report on Executive Compensation."
 
                                       4
<PAGE>
 
DIRECTOR COMPENSATION
 
  Directors of the Company receive no cash compensation for their services as
members of the Board of Directors, although their out-of-pocket expenses
incurred on behalf of the Company are reimbursed. Prior to October 1995, the
Company's 1993 Stock Option Plan provided for the automatic grant to each
director who is not an employee of the Company an option to purchase 888 shares
of Common Stock on each anniversary of their initial election to the Board,
which became exercisable one year after the date of the grant. On October 3,
1995, this provision in the 1993 Stock Option Plan was terminated and all of
the non-employee directors of the Company were granted an option to purchase
15,555 shares of Common Stock at a price of $2.70 per share. These options
become exercisable, on a cumulative basis, with respect to 25% of the shares
covered by the option, on each of the first four anniversary dates of the
grant.
 
                     PRINCIPAL STOCKHOLDERS AND BENEFICIAL
                            OWNERSHIP OF MANAGEMENT
 
  The following table sets forth information regarding the beneficial ownership
of the Common Stock of the Company as of March 12, 1997, unless otherwise
noted, (a) by each stockholder who is known by the Company to own beneficially
more than 5% of the outstanding Common Stock; (b) by each director; (c) by each
executive officer named in the Summary Compensation Table; and (d) by all
executive officers and directors of the Company as a group.
 
<TABLE>
<CAPTION>
                                                       SHARES OF COMMON STOCK
                                                       BENEFICIALLY OWNED(1)
                                                       ---------------------------
                                                                     PERCENT OF
NAME                                                     AMOUNT       CLASS(2)
- ----                                                   ------------- -------------
<S>                                                    <C>           <C>
Norwest Venture Capital(3)...........................        863,367       10.3%
New Enterprise Associates V, Limited Partnership,
 Catalyst Ventures, Limited Partnership and Chemicals
 and Materials Enterprise Associates, Limited
 Partnership(4)......................................        486,216        5.8%
Trustees of the General Electric Pension Trust(5)....        476,190        5.7%
Coral Partners II, a limited partnership(6)..........        444,859        5.3%
Sam B. Humphries(7)..................................        176,154        2.1%
Promod Haque, Ph.D.(8)...............................        870,142       10.4%
Peter H. McNerney(9).................................        453,058        5.4%
John M. Nehra(10)....................................         73,785       *
Demetre M. Nicoloff, M.D.(11)........................         61,341       *
Gary A. Peterson(12).................................         92,941        1.1%
Paulita M. LaPlante(13)..............................         50,975       *
Byron (Buzz) Moran...................................         46,888       *
Wesley G. Peterson(14)...............................         50,717       *
All directors and executive officers as a group (9
 persons)(15)........................................      1,876,001       22.0%
</TABLE>
- --------
   * Less than 1% of the outstanding shares.
(1) Except as otherwise indicated in the footnotes to this table, the persons
    named in the table have sole voting and investment power with respect to
    all shares of Common Stock. Shares of Common Stock subject to options or
    warrants currently exercisable or exercisable within 60 days are deemed
    outstanding for computing the percentage of the person or group holding
    such options but are not deemed outstanding for computing the percentage of
    any other person or group.
(2) Based on 8,349,279 shares of Common Stock outstanding as of March 12, 1997.
(3) Includes 366,833 shares held of record by Norwest Equity Partners IV and
    453,225 shares held of record by Norwest Equity Partners V. Also includes
    32,564 and 10,744 shares issuable upon
 
                                       5
<PAGE>
 
    exercise of outstanding warrants held by Norwest Equity Partners IV and
    Norwest Equity Partners V, respectively. Itasca Partners is the general
    partner of Norwest Equity Partners IV and may be deemed to be the
    beneficial owner of shares held by Norwest Equity Partners IV. Itasca
    Partners V is the general partner of Norwest Equity Partners V and may be
    deemed to be the beneficial owner of shares held by Norwest Equity
    Partners V. Daniel J. Haggerty, by virtue of his affiliation with Norwest
    Equity Partners IV and Norwest Equity Partners V, may be deemed to be the
    beneficial owner of shares held by Norwest Equity Partners IV and Norwest
    Equity Partners V; however he disclaims beneficial ownership of such
    shares, except to the extent of his pecuniary interest therein. John E.
    Lindahl and George J. Still, by virtue of their affiliation with Norwest
    Equity Partners V, each may be deemed to be the beneficial owner of shares
    held by Norwest Equity Partners V; however they disclaim beneficial
    ownership of such shares, except to the extent of their pecuniary interest
    therein. The address of Norwest Venture Capital and the other named
    individuals is 2800 Piper Tower, 222 South Ninth Street, Minneapolis,
    Minnesota 55402. Promod Haque, Ph.D., a director of the Company, is a
    general partner of Itasca Partners and Itasca Partners V and is an officer
    of Norwest Venture Capital Management, Inc. Does not include shares held
    of record by Dr. Haque. See note (8) below.
(4) Based on a Schedule 13G dated February 10, 1997. Catalyst Ventures,
    Limited Partnership ("Catalyst") is the record owner of 31,365 shares of
    Common Stock and holds warrants to purchase an aggregate of 33,625 shares;
    New Enterprise Associates IV, Limited Partnership ("NEA IV"), which is a
    general partner of Catalyst, is the record owner of 106 shares; New
    Enterprise Associates V, Limited Partnership ("NEA V") is the record owner
    of 281,924 shares and holds warrants to purchase an aggregate of 40,551
    shares; Chemicals and Materials Partners, Limited Partnership ("CMEA") is
    the record owner of 97,018 shares and holds a warrant to purchase 1,627
    shares. As a general partner of Catalyst and the holder of 106 shares, NEA
    IV may be deemed to own beneficially shares owned of record by Catalyst
    and NEA IV. As the sole general partner of NEA IV, which is the general
    partner of Catalyst and the holder of shares owned by NEA IV, NEA Partners
    IV, Limited Partnership ("NEA Partners IV") may be deemed to own
    beneficially shares held of record by Catalyst and NEA IV. As the sole
    general partner of NEA V, NEA Partners V, Limited Partnership ("NEA
    Partners V") may be deemed to own beneficially shares held of record by
    NEA V. As a general partner of CMEA, NEA Chemicals and Materials Partners,
    Limited Partnership ("CMEA Partners") may be deemed to own beneficially
    the shares held of record by CMEA. By virtue of their relationship as
    affiliated limited partnerships, certain of whose general partners share
    some of the same individual general partners, each of Catalyst, NEA IV,
    NEA V and CMEA and their general partners, NEA Partners IV, the sole
    general partner of NEA IV, NEA Partners V, the sole general partner of NEA
    V, and CMEA Partners, a general partner of CMEA, share voting and
    investment power with respect to and may be deemed to own beneficially all
    of the shares held of record by Catalyst, NEA IV, NEA V and CMEA, for a
    total of 486,216 shares. John Nehra, a director of the Company, is a
    general partner of Catalyst. Does not include shares held of record by Mr.
    Nehra. The address of the foregoing entities is 1119 St. Paul Street,
    Baltimore, Maryland 21202. See note (10) below.
(5) Based on a Schedule 13G dated February 14, 1997. General Electric
    Investment Corporation ("GEIC") is the investment advisor to the Trustees
    of the General Electric Pension Trust ("GEPT") and may be deemed a
    beneficial owner of such shares. GEPT and GEIC share voting and investment
    power with respect to such shares. The address of GEPT and GEIC is 3003
    Summer Street, Stamford, Connecticut 06904-7900.
(6) Includes 4,034 shares issuable upon exercise of outstanding warrants held
    by Coral Partners II, a limited partnership ("Coral Partners II") and
    6,220 shares issuable upon exercise of options held by Coral Group Inc.
    ("Coral"). Coral Management Partners II, Limited Partnership ("CMP II"),
    is the general partner of Coral Partners II. Coral is the management
    company of CMP II. Mr. McNerney is a general partner of CMP II and a
    shareholder and officer of Coral. Mr. McNerney may be deemed to share
    beneficial ownership with respect to such shares; however, he
 
                                       6
<PAGE>
 
    disclaims beneficial ownership except to the extent of his pecuniary
    interest therein. Does not include any shares held of record by Mr.
    McNerney. The address of Coral Partners II is 60 South 6th Street, Suite
    3510, Minneapolis, Minnesota 55402. See note (9) below.
(7) Includes 227 shares issuable upon exercise of outstanding warrants held by
    Mr. Humphries. Mr. Humphries' address is 7615 Golden Triangle Drive, Suite
    A, Minneapolis, Minnesota 55344.
(8) Includes 6,775 shares issuable upon exercise of outstanding options held
    by Dr. Haque. Also includes all shares beneficially owned by Norwest
    Equity Partners IV and Norwest Equity Partners V, as to which shares Dr.
    Haque disclaims beneficial ownership except to the extent of any pecuniary
    interest therein. Dr. Haque's business address is Norwest Venture Capital,
    245 Litton Avenue, Suite 250, Palo Alto, California 94301. See note (3)
    above.
(9) Includes all shares beneficially owned by Coral Partners II, as to which
    Mr. McNerney disclaims any beneficial ownership except to the extent of
    any pecuniary interest therein. Mr. McNerney has the same business address
    as Coral Partners II. See note (6) above.
(10) Includes 6,775 shares of Common Stock issuable upon exercise of
     outstanding options held by Mr. Nehra. Also includes all shares
     beneficially owned by Catalyst, of which Mr. Nehra is a general partner
     and as to which Mr. Nehra disclaims any beneficial ownership except to
     the extent of any pecuniary interest therein. Mr. Nehra has the same
     business address as Catalyst. See note (4) above.
(11) Includes 8,195 shares issuable upon exercise of outstanding stock options
     and warrants held by Dr. Nicoloff.
(12) Includes 12,765 shares issuable upon exercise of outstanding options and
     warrants held by Mr. Peterson. Also includes 68,796 shares held of record
     by PSF Health Care Fund L.P. ("PSF"), 555 shares issuable upon exercise
     of options held by PSF, as to which Mr. Peterson disclaims any beneficial
     ownership except to the extent of any pecuniary interest therein. PSF
     Advisors is the general partner of PSF, and Mr. Peterson is a general
     partner of PSF Advisors.
(13) Includes 48,889 shares issuable upon exercise of outstanding options held
     by Ms. LaPlante.
(14) Includes 11,689 shares issuable upon exercise of outstanding options held
     by Mr. Peterson.
(15) Includes 183,054 shares issuable upon exercise of outstanding options and
     warrants held by officers and directors or their affiliates. Also
     includes all shares beneficially owned by Norwest Equity Partners IV,
     Norwest Equity Partners V, Catalyst, Coral Partners II, Coral and PSF.
     See notes (3), (4), (6) and (12) above.
 
                                       7
<PAGE>
 
                   EXECUTIVE COMPENSATION AND OTHER BENEFITS
 
SUMMARY OF CASH AND CERTAIN OTHER COMPENSATION
 
  The following table provides summary information concerning cash and non-
cash compensation paid to or earned by the Company's Chief Executive Officer
and the executive officers of the Company, all of whom received or earned cash
and non-cash salary and bonus of more than $100,000 for the fiscal year ended
December 31, 1996 (the "Named Executive Officers").
 
                          SUMMARY COMPENSATION TABLE
 
<TABLE>
<CAPTION>
                                                                             LONG-TERM
                                              ANNUAL COMPENSATION           COMPENSATION
                                    ---------------------------------------  SECURITIES    ALL OTHER
                                                             OTHER ANNUAL    UNDERLYING   COMPENSATION
NAME AND PRINCIPAL POSITION         YEAR SALARY($) BONUS($) COMPENSATION($)  OPTIONS(#)      ($)(1)
- ---------------------------         ---- --------- -------- --------------- ------------  ------------
<S>                                 <C>  <C>       <C>      <C>             <C>           <C>
Sam B. Humphries                    1996 $175,717  $46,126      $6,000(2)      27,222        $2,365
President and Chief Executive Of-
 ficer                              1995  172,992   60,000       6,000(2)     272,222         2,110
                                    1994  172,992        0       6,000(2)           0         1,800
Paulita M. LaPlante                 1996  114,316   27,000           0          8,889             0
Vice President of Worldwide Sales,  1995   94,630   28,000           0         88,888             0
Marketing and Business Development  1994   80,400        0           0          2,500(3)          0
Byron (Buzz) Moran                  1996  130,000   25,000      47,122(4)      11,722             0
Vice President of Research and      1995  130,000   25,000      40,927(4)     117,222             0
Development and Operations          1994   41,000        0      11,537(4)      48,915(3)          0
Wesley G. Peterson                  1996   97,000   24,000           0          6,044             0
Chief Financial Officer, Vice
 President                          1995   85,854   26,000           0         60,444             0
of Finance and Administration       1994   80,900        0           0          2,222(3)          0
</TABLE>
- --------
(1) Consists of life insurance premiums paid by the Company on behalf of Mr.
    Humphries.
(2) Consists of a car allowance of $500 per month.
(3) Such options were canceled in August 1995.
(4) Consists of amounts reimbursed by the Company for relocation and temporary
    living expenses.
 
OPTION GRANTS AND EXERCISES
 
  The following tables summarize option grants and exercises during the year
ended December 31, 1996 to or by the Named Executive Officers and the
potential realizable value of the options held by such persons at December 31,
1996.
 
                       OPTION GRANTS IN LAST FISCAL YEAR
 
<TABLE>
<CAPTION>
                                                                              POTENTIAL
                                                                          REALIZABLE VALUE
                                                                          AT ASSUMED ANNUAL
                                                                           RATES OF STOCK
                                                                                PRICE
                                                                          APPRECIATION FOR
                                      INDIVIDUAL GRANTS (1)                OPTION TERM(2)
                         ------------------------------------------------ -----------------
                          NUMBER OF
                         SECURITIES  PERCENT OF TOTAL EXERCISE
                         UNDERLYING  OPTIONS GRANTED  OR BASE
                           OPTIONS     TO EMPLOYEES    PRICE   EXPIRATION
NAME                     GRANTED (#)  IN FISCAL YEAR   ($/SH)     DATE       5%      10%
- ----                     ----------- ---------------- -------- ---------- -------- --------
<S>                      <C>         <C>              <C>      <C>        <C>      <C>
Sam B. Humphries........   27,222         18.0%        $6.00    9/8/2006  $102,719 $260,309
Paulita M. LaPlante.....    8,889          5.9%         6.00    9/8/2006    33,541   85,001
Byron (Buzz) Moran......   11,722          7.7%         6.00    9/8/2006    44,231  112,091
Wesley G. Peterson......    6,044          4.0%         6.00    9/8/2006    22,806   57,795
</TABLE>
 
                                       8
<PAGE>
 
- --------
(1) All of the options granted to executives were granted under the Company's
    1993 Stock Option Plan. The foregoing options become exercisable at the
    rate of 25% of the number of shares covered by such option on each of the
    first four anniversary dates of the grant of such option, so long as the
    executive remains employed by the Company or one of its subsidiaries. To
    the extent not already exercisable, options under the plan become
    immediately exercisable in full upon certain changes in control of the
    Company and remain exercisable for the remainder of their term. See
    "Executive Compensation and Other Benefits--Change in Control
    Arrangements."
(2) These amounts represent certain assumed rates of appreciation only. Actual
    gains, if any, on stock option exercises are dependent upon the future
    performance of the Company's Common Stock, overall market conditions and
    the executive's continued employment with the Company. The amounts
    represented in this table might not necessarily be achieved.
 
                        AGGREGATED OPTION EXERCISES IN
              LAST FISCAL YEAR AND FISCAL YEAR-END OPTION VALUES
 
<TABLE>
<CAPTION>
                                                       NUMBER OF SECURITIES
                                                      UNDERLYING UNEXERCISED   VALUE OF UNEXERCISED IN-
                                                            OPTIONS AT           THE-MONEY OPTIONS AT
                             SHARES                      DECEMBER 31, 1996       DECEMBER 31, 1996(1)
                           ACQUIRED ON    VALUE      ------------------------- -------------------------
NAME                     EXERCISE (#)(2) REALIZED    EXERCISABLE UNEXERCISABLE EXERCISABLE UNEXERCISABLE
- ----                     --------------- --------    ----------- ------------- ----------- -------------
<S>                      <C>             <C>         <C>         <C>           <C>         <C>
Sam B. Humphries........          0      $      0           0       27,222      $      0     $ 54,444
Paulita M. LaPlante.....          0             0      48,889       48,889       347,111      301,778
Byron (Buzz) Moran......     23,444       131,286(3)        0       82,055             0      522,808
Wesley G. Peterson......          0             0      11,689       33,245        82,992      205,215
</TABLE>
- --------
(1) Value based on the difference between the fair market value of the Common
    Stock on December 31, 1996 ($8.00) and the exercise price of the options.
(2) The exercise price may be paid in cash, pursuant to a cashless exercise
    procedure under which the executive provides irrevocable instructions to a
    brokerage firm to sell the purchased shares and to remit to the Company,
    out of the sale proceeds, an amount equal to the exercise price plus all
    applicable withholding taxes or, in the Compensation Committee's
    discretion, by delivery of a promissory note or shares of Common Stock
    valued at the fair market value on the date of exercise.
(3) Value based on the difference between the fair market value of the Common
    Stock on the date of exercise ($6.50) and the exercise price of the
    options ($.90).
 
EMPLOYMENT AGREEMENT
 
  The Company entered into an Employment Agreement with Mr. Humphries in
October 1991. The agreement had an initial term through November 1992, and
provides for automatic renewal for additional one-year periods unless either
party gives notice of termination to the other not less than 60 days before
the expiration of the then current term. Mr. Humphries has a current base
salary of $185,000 per year, which may be increased by the Board of Directors,
and is entitled to receive an annual incentive bonus at the discretion of the
Board of Directors. Mr. Humphries also receives an automobile allowance of
$500 per month. The agreement requires Mr. Humphries to assign to the Company
patents and other proprietary rights related to the Company's business and to
keep the Company's proprietary information confidential. Mr. Humphries is also
prohibited from competing with the Company for a period of one year following
the termination of his employment with the Company.
 
  In connection with the employment agreement, the Company granted Mr.
Humphries stock options to purchase an aggregate of 121,162 shares of Common
Stock at a price of $9.00 per share, which would have vested at various times
through October 1, 1996. On August 2, 1995, the Board of Directors granted Mr.
Humphries a Non-Statutory Option to purchase 272,222 shares of Common
 
                                       9
<PAGE>
 
Stock at an exercise price of $0.90 per share expiring ten years after the
grant date, and canceled Mr. Humphries' prior options. This option was granted
as part of a grant of options to all employees of the Company at the same
exercise price. On September 1, 1995, Mr. Humphries exercised this option and
paid for the shares by executing a non-recourse promissory note in the amount
of $245,000 in favor of the Company, which is secured by a pledge of the shares
acquired. A total of 122,499 shares are subject to forfeiture should Mr.
Humphries' employment with the Company terminate prior to August 2, 1999. The
fair market value of shares subject to the pledge must be at least 200% of the
principal amount of the note outstanding from time to time. The note bears
interest at the rate of 5.91% per year, which is payable, annually. The note
becomes due on August 1, 1998.
 
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
 
  John M. Nehra and Gary A. Peterson served as members of the Company's
Compensation Committee during 1996. Mr. Nehra is the Managing General Partner
of Catalyst Ventures Limited Partnership, and Mr. Peterson is a General Partner
of PSF Advisors, the General Partner of PSF Health Care Fund L.P., each of
which is an investor in the Company. See "Principal Stockholders and Beneficial
Ownership of Management." No other relationships existed during 1996 with
respect to Mr. Nehra or Mr. Peterson that would be required to be disclosed
under the rules of the Securities Act of 1933, as amended (the "Securities
Act").
 
COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION
 
  The Compensation Committee of the Board of Directors currently consists of
John M. Nehra and Gary A. Peterson. The Compensation Committee makes
recommendations to the Board of Directors concerning the compensation of the
Company's directors, executive officers and key managers, and acts on such
other matters relating to their compensation as it deems appropriate. In
addition, the Compensation Committee administers the Company's stock option
plans, pursuant to which incentive stock options and non-statutory stock
options may be granted to eligible key employees, officers, directors and
consultants of the Company. It is also intended that the Compensation Committee
will administer the Company's Employee Stock Purchase Plan.
 
  COMPENSATION PHILOSOPHY AND OBJECTIVES. The philosophy underlying the
decisions and recommendations of the Compensation Committee is to recognize and
reward results and achievement at the Company and individual level by linking
compensation to such achievement. Consistent with this philosophy, the
Compensation Committee has set the following objectives for the Company's
executive compensation program:
 
  . Motivate officers to achieve desired Company performance goals by
    rewarding such achievements.
 
  . Provide a program of compensation that is competitive with comparable
    companies to enable the Company to attract and retain key executive
    talent.
 
  . Align the interests of the Company's executives with the interests of the
    Company's stockholders by linking compensation to the Company's
    performance and by providing the Company's executives with long-term
    opportunities for stock ownership.
 
  In determining its recommendations as to the compensation of the Company's
executives, the Compensation Committee considers factors such as Company
performance, both in isolation and in comparison to companies of comparable
development, complexity and size; the individual performance of each executive
officer; historical compensation levels at the Company; the overall competitive
environment for executives and the level of compensation necessary to attract
and retain the level of key executive talent desired by the Company. The
Compensation Committee places primary emphasis on Company performance rather
than individual performance as measured against goals approved by the
Compensation Committee. In analyzing these factors, the Compensation Committee
may from time
 
                                       10
<PAGE>
 
to time review competitive compensation data gathered in comparative surveys or
collected by independent consultants.
 
  EXECUTIVE COMPENSATION PROGRAM COMPONENTS. The Company's executive
compensation program consists of base salary, annual cash performance bonuses,
and long-term incentive opportunities under the Company's stock option plans.
Each element of the compensation program is discussed in greater detail below.
 
    Base Salary. The Compensation Committee's recommendations regarding the
  base salary of each executive officer of the Company, including the
  compensation of Mr. Humphries as Chief Executive Officer, are based on a
  number of factors, including the executive officer's experience and
  qualifications, the potential impact of the individual on the Company's
  performance, the level of skill and responsibility required by the
  individual's position and the other factors described above. Base salaries
  are determined for each year prior to the beginning of the year. In
  general, the Compensation Committee seeks to set executive officer base
  salaries at moderately to aggressively competitive levels in relation to
  the companies with which the Company competes for executives. Effective
  October 1, 1996, Mr. Humphries' base salary was increased from $173,000 to
  $185,000. In addition, base salaries for some of the Company's other
  executive officers were increased in 1996 from 1995 levels. All of these
  increases were based upon a review of the foregoing factors, particularly
  the performance of the individual officers and their base salaries relative
  to salaries being paid by other companies of similar size and development
  for officers with similar responsibilities.
 
    Annual Management Performance Bonuses. The Company's annual management
  performance bonus program is designed to provide a direct financial
  incentive to the Company's executive officers, including the Chief
  Executive Officer, for the achievement of specific Company performance
  goals. At the beginning of each year, the Compensation Committee
  establishes a maximum annual bonus, as a percentage of base salary, that
  the Chief Executive Officer and the other executive officers of the Company
  are eligible to receive and the goals against which performance will be
  measured in determining annual bonuses after the conclusion of the year.
  The amount of the annual performance bonus to be paid is based on a
  recommendation from the Compensation Committee to the full Board of
  Directors after the conclusion of the year. For 1996, the Compensation
  Committee approved financial and non-financial goals for the management
  performance bonus program. The non-financial goals for 1996 primarily
  related to completing various sales and marketing initiatives, completing
  certain product development activities, filing regulatory submissions for
  new products and establishing marketing relationships. These goals were
  established to motivate the executive officers to achieve milestones that
  would impact the Company's long-term value. Although the Company did not
  meet the financial goal with respect to revenues, the Company met or
  exceeded all of the other financial goals and all of the non-financial
  goals (except for the timing of product launch) established by the
  Compensation Committee at the beginning of 1996. In addition, the Company
  achieved a number of significant milestones that had not been part of the
  bonus plan. The Compensation Committee concluded that the Company's failure
  to generate significant revenues was largely beyond the control of the
  Company's officers, primarily due to a series of delays in the commercial
  release by the Company's development partner of a new software program.
  Based on the foregoing factors, the Compensation Committee recommended to
  the Board that 1996 bonuses for the Company's executive officers, including
  the Chief Executive Officer, be paid at less than the maximum level
  approved at the beginning of the year, and the Board approved the
  committee's recommendation.
 
    Long-Term Incentive Compensation. The Compensation Committee makes long-
  term incentive compensation available to the Company's executive officers,
  as well as all other
 
                                       11
<PAGE>
 
  employees of the Company, through the grant of stock options. The purpose
  of stock option grants is to advance the interests of the Company and its
  stockholders by enabling the Company to attract and retain persons of
  ability to perform services for the Company, including persons performing
  services to the Company as executive officers. By granting stock options to
  executive officers and other employees, the Compensation Committee seeks to
  align the long- term interests of these individuals with those of the
  Company's stockholders by creating a strong and direct nexus between
  compensation and stockholder return and to enable executive officers and
  key managers to develop and maintain a significant ownership position in
  the Company. The Compensation Committee determines the number of options
  and the terms and conditions of such options based on certain factors,
  including the past performance of the executive officer, the executive
  officer's potential impact on the achievement of the Company's objectives,
  past grants or awards of stock-based compensation and on comparative
  compensation data regarding option grants by Company's within the medical
  device industry as well as within a broader group of companies of
  comparable size and complexity. Additionally, options may be granted to an
  executive officer as an incentive at the time the executive officer joins
  the Company. All options granted by the Compensation Committee have an
  exercise price equal to 100% of the fair market value of the Common Stock
  on the date of grant. In general, options vest at the rate of 25% of the
  shares covered by the option each year over a period of four years and
  remain exercisable for a period of 10 years from the date of grant,
  provided the individual continues to be employed by the Company. In 1996,
  the Compensation Committee granted options to all executive officers of the
  Company and key managers of the Company covering a number of shares equal
  to 10% of the aggregate number of shares subject to options previously
  granted to these individuals. The primary purpose of the 1996 stock option
  grants was to recognize the outstanding individual contributions being made
  by these individuals during a year in which the Company's revenue
  objectives could not be met and in recognition of the fact that annual cash
  bonuses were likely to be reduced as a result.
 
  SECTION 162(M). Section 162(m) of the Internal Revenue Code of 1986, as
amended (the "Code"), limits the deductibility of certain compensation paid to
the chief executive officer and each of the four other most highly compensated
executives of a publicly held corporation to $1,000,000. In 1996, the Company
did not pay "compensation" within the meaning of Section 162(m) to such
executive officers in excess of $1,000,000, and does not believe it will do so
in the near future. Therefore, the Company does not have a policy at this time
regarding qualifying compensation paid to its executive officers for
deductibility under Section 162(m), but will formulate such a policy if
compensation levels ever approach $1,000,000.
 
                                          Compensation Committee
 
                                          John M. Nehra
                                          Gary A. Peterson
 
COMPARATIVE STOCK PERFORMANCE
 
  The graph below compares, for the period from February 14, 1996, the date of
the Company's initial public offering, to December 31, 1996, the total
cumulative shareholder return on the Company's Common Stock to the total
cumulative return on the Standard & Poor's 500 Stock Index and a peer- group
selected in good faith by the Company consisting of the following companies:
Datascope Corporation; Diametrics Medical, Inc.; i-Stat Corporation; Marquette
Medical Systems, Inc.; Nellcor Puritan Bennet Incorporated; Protocol Systems,
Inc.; and Spacelabs Medical, Inc. The peer group consists of public companies
in the Company's industry that market arterial blood gas measurement systems or
critical care patient bedside monitoring systems, and the peer-group companies
were
 
                                       12
<PAGE>
 
selected on that basis. The graph assumes a $100 investment in the Company's
Common Stock, the Standard & Poor's 500 Stock Index and the peer-group on
February 14, 1996 and the reinvestment of all dividends.

<TABLE> 
<CAPTION> 
- -----------------------------------------------------------------------------
                                      February 14, 1996     December 31, 1996
- -----------------------------------------------------------------------------
<S>                                   <C>                   <C>  
Optical Sensors Incorporated                 $100               $ 62.00
- -----------------------------------------------------------------------------
Standard & Poor's 500 Stock Index            $100               $115.00
- -----------------------------------------------------------------------------
Corporate Peer Group                         $100               $ 80.00
- -----------------------------------------------------------------------------
</TABLE> 

CHANGE IN CONTROL ARRANGEMENTS
 
  Under the Company's 1993 Stock Option Plan, as amended (the "1993 Plan"),
upon the occurrence of a "change in control" all outstanding options granted
under the 1993 Plan will become and remain exercisable in full during their
remaining terms regardless of whether the plan participants thereafter remain
employees of the Company or a subsidiary. The acceleration of the
exercisability of options under the 1993 Plan may be limited, however, if the
acceleration would be subject to an excise tax imposed upon "excess parachute
payments." Under the 1993 Plan, a "change in control" has occurred in the
event of (a) the sale, lease, exchange or other transfer of all or
substantially all of the assets of the Company (in one transaction or in a
series of related transactions) to a corporation that is not controlled by the
Company; (b) the approval by the shareholders of the Company of any plan or
proposal for the liquidation or dissolution of the Company; (c) a change in
control of the Company of a nature that would be required to be reported
pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934, as
amended (the "Exchange Act"), whether or not the Company is then subject to
such reporting requirement; (d) any person becomes the "beneficial owner,"
directly or indirectly, of 50% or more of the combined voting power of the
Company's outstanding securities ordinarily having the right to vote at
elections of directors; or (e) individuals who constitute the board of
directors of the Company on the effective date of the 1993 Plan cease for any
reason to constitute at least a majority thereof, provided that any person
becoming a director subsequent to the effective date of the 1993
 
                                      13
<PAGE>
 
Plan whose election, or nomination for election by the Company's shareholders,
was approved by a vote of at least a majority of the directors comprising the
board of directors of the Company on the effective date of the 1993 Plan
(either by a specific vote or by approval of the proxy statement of the Company
in which such person is named as a nominee for director, without objection to
such nomination) shall be considered as though such person were a member of the
board of directors of the Company on the effective date of the 1993 Plan. In
addition, the Compensation Committee, with the consent of any affected
participant, may determine that some or all of the participants holding
outstanding options will receive cash in an amount equal to the excess of the
fair market value of such shares immediately before the effective date of the
change in control over the exercise price per share of the options. In
addition, certain forfeiture restrictions that apply to certain shares of
Common Stock currently held by Mr. Humphries would expire upon a change in
control as described above if Mr. Humphries employment with the Company was
terminated following such change in control.
 
                              CERTAIN TRANSACTIONS
 
  The Company has entered into an employment agreement and a related stock
option agreement covering 272,222 shares of Common Stock with Sam B. Humphries,
its Chief Executive Officer. On September 1, 1995, Mr. Humphries exercised this
option and paid for the shares by executing a non- recourse promissory note in
the amount of $245,000 in favor of the Company, which is secured by a pledge of
the shares acquired. The fair market value of shares subject to the pledge must
be at least 200% of the principal amount of the note outstanding from time to
time. The note bears interest at the rate of 5.91% per year, which is payable
annually. The note becomes due on August 1, 1998. See "Executive Compensation
and Other Benefits--Employment Agreement."
 
                               PROPOSAL TO ADOPT
                          EMPLOYEE STOCK PURCHASE PLAN
 
                                   PROPOSAL 2
 
  On December 3, 1996, the Board of Directors of the Company adopted the
Employee Stock Purchase Plan (the "Purchase Plan"), subject to approval by the
stockholders at the Annual Meeting. The Purchase Plan provides for the purchase
of Common Stock by eligible employees of the Company and its subsidiaries
through payroll deductions. Under the Purchase Plan, the Company conducts a
series of continuous offerings (each, an "Offering") of its Common Stock, each
continuing for three months except for the initial offering period (the
"Offering Period") and each beginning on February 1, May 1, August 1 and
November 1 of each year, as the case may be (the "Offering Date"), and ending
on the following April 30, July 31, October 31 and January 31 (the "Termination
Date"), respectively. The first Offering under the Purchase Plan has an
Offering Date of January 1, 1997 and a Termination Date of April 30, 1997. On
each Offering Date, each eligible participating employee (the "Participant") in
the Purchase Plan will be granted, by operation of the Purchase Plan, an option
(a "Purchase Plan Option") to purchase as many full shares of Common Stock as
can be purchased with payroll deductions authorized by the Participant and
credited to the Participant's account during that Offering.
 
  The purpose of the Purchase Plan is to advance the interests of the Company
and its stockholders by providing employees of the Company and its subsidiaries
with an opportunity to acquire an ownership interest in the Company through the
purchase of shares of Common Stock of the Company on favorable terms through
payroll deductions.
 
 
                                       14
<PAGE>
 
  The major features of the Purchase Plan are summarized below, which summary
is qualified in its entirety by reference to the actual text of the Purchase
Plan, a copy of which may be obtained from the Company.
 
SUMMARY OF THE PURCHASE PLAN
 
  General. Any employee of the Company or any subsidiary, including any
officer, whose customary employment is for more than 20 hours per week and who
is employed by the Company or a subsidiary on December 3, 1996 or if hired
after such date has been continuously employed for at least one month prior to
the Offering Date of the relevant Offering, will be eligible to participate in
that Offering. The maximum number of shares of Common Stock reserved for sale
under the Purchase Plan is 200,000 shares.
 
  The number and type of shares of Common Stock subject to outstanding Purchase
Plan Options and the exercise price of outstanding Purchase Plan Options will
be appropriately adjusted in the event such Purchase Plan Options are exercised
after any Common Stock dividend, split-up, recapitalization, merger,
consolidation, combination or exchange of Common Stock or the like. If the
total number of shares that would otherwise be subject to Purchase Plan Options
granted on an Offering Date exceeds the number of shares then available under
the Purchase Plan (after deduction of all shares for which Purchase Plan
Options have been exercised or are then outstanding), the Company will make a
pro rata allocation of the shares remaining available for Purchase Plan Option
grants in as uniform and equitable a manner as is practicable. If this occurs,
the Company will give written notice of such reduction of the number of shares
subject to the Purchase Plan Option to each affected Participant and will
return any excess funds accumulated in each Participant's account as soon as
practicable after the Termination Date of such Offering.
 
  The Purchase Plan is currently administered by the Compensation Committee
(the "Committee") of the Board. Members of the Committee are appointed from
time to time by the Board, serve at the pleasure of the Board, and may resign
at any time upon written notice to the Board. The Committee has the authority
to make, administer and interpret such rules and regulations as it deems
necessary to administer the Purchase Plan.
 
  Participation. An eligible employee may become a Participant in the Purchase
Plan by completing a subscription agreement authorizing payroll deductions on
the form provided by the Company and filing it with the Company's Human
Resources Department not less than 15 days before the Offering Date of the
first Offering in which the Participant wishes to participate. Payroll
deductions for a Participant will begin with the first payroll following the
applicable Offering Date and will continue until the termination date of the
Purchase Plan, subject to termination by the Participant at any time, as
described below under the heading "Withdrawal and Termination of Employment."
An otherwise eligible employee will not be granted a Purchase Plan Option under
the Purchase Plan if: (i) immediately after the grant, the Participant would
own shares of Common Stock and/or hold outstanding options to purchase shares
of Common Stock possessing 5% or more of the total combined voting power or
value of all classes of shares of the Company or of any subsidiary; or (ii) the
rate at which the employee has elected to have payroll deductions withheld
under such Purchase Plan Option would permit the Participant to purchase shares
of Common Stock to accrue at a rate exceeding $25,000 of the fair market value
of such shares (determined as of the Offering Date) for each calendar year in
which such Purchase Plan Option is outstanding at any time. As of March 1,
1997, approximately 71 persons were eligible to participate in the Purchase
Plan.
 
  Payroll Deductions. By completing and filing a participation form, a
Participant elects to have payroll deductions made from the Participant's total
compensation on each payday during the Offering Period at a rate equal to a
whole percentage from 1% to 10% of the total compensation that he or she
 
                                       15
<PAGE>
 
would have received on the payday; provided, however, that no Participant's
payroll deductions may be less than $10.00 per pay period. No increases or
decreases in the amount of payroll deductions for a Participant may be made
during an Offering. A Participant may increase or decrease the rate of the
Participant's payroll deductions under the Purchase Plan to a whole percentage
from 1% to 10% for subsequent Offerings by completing an amended participation
form at least 15 days prior to the Offering Date for which the increase or
decrease is to become effective. A Participant may discontinue participation
in the Purchase Plan at any time as described below under the heading
"Withdrawal and Termination of Employment."
 
  The funds accumulated through a Participant's payroll deductions under the
Purchase Plan are credited to an account established under the Purchase Plan
for the Participant. These funds are held by the Company as part of its
general assets, usable for any corporate purpose, and the Company is not
obligated to keep these funds separate from its other corporate funds.
Participants will not receive any interest from the Company for the funds
accumulated from their payroll deductions under the Purchase Plan and may not
make any separate cash payment or contribution to such account.
 
  Purchase of Shares. On each Offering Date, each Participant is granted, by
operation of the Purchase Plan, a Purchase Plan Option to purchase as many
shares of the Company's Common Stock that he or she will be able to purchase
with the payroll deductions credited to the Participant's account during the
Offering Period. Unless a Participant gives written notice as specified in the
Purchase Plan or withdraws from the Purchase Plan, the Participant's Purchase
Plan Option for the purchase of shares will be exercised automatically on the
Termination Date for the purchase of the number of shares of Common Stock that
the accumulated payroll deductions in the Participant's account on the
Termination Date will purchase at the applicable price, determined in the
manner described below. Any cash remaining in a Participant's account under
the Purchase Plan after a purchase by the Participant of shares at the
termination of each Offering Period which is insufficient to purchase a full
share of Common Stock will be deemed to have purchased a fractional share of
Common Stock as of the Termination Date, with such fractional share calculated
to the third decimal point. Notwithstanding the foregoing, in no event may the
number of shares purchased by any Participant during an Offering exceed 1,500
shares of Common Stock.
 
  The per share purchase price of the shares offered in a given Offering will
be the lesser of 85% of the fair market value of one share of the Common Stock
of the Company on the Offering Date or the Termination Date. Fair market value
of the Common Stock purchased is the closing sale price of the Common Stock,
rounded up to the next highest full cent, as reported by the Nasdaq National
Market on the applicable date or, if no shares were traded on such day, as of
the next preceding day on which there was such a trade.
 
  The shares purchased in the Offering will be held by Norwest Bank Minnesota,
N.A. ("Norwest"), the transfer agent and registrar for the Common Stock, for
the benefit of the Participants in accordance with their respective interests,
and the Company will cause Norwest to deliver to each Participant, as soon as
practicable after each Termination Date, a statement of such Participant's
account, showing the number of shares purchased in the Offering and the total
number of shares held for the Participant's account. All shares purchased by a
Participant in an Offering and in any subsequent Offerings will accumulate for
the benefit of the Participant until the Participant's withdrawal or
termination. A Participant may request that a certificate representing the
number of whole shares of Common Stock purchased under the Purchase Plan be
issued by making a written request to Norwest.
 
  No Participant will have any interest in any shares of Common Stock subject
to a Purchase Plan Option under the Purchase Plan until the Purchase Plan
Option has been exercised, at which point the interest will be strictly that
of a purchaser of the shares of Common Stock purchased upon such
 
                                      16
<PAGE>
 
exercise, pending the credit of such shares of Common Stock to the
Participant's account, as described above.
 
  Non-Transferability of Purchase Plan Options. Neither payroll deductions
credited to a Participant's account nor any rights with regard to the exercise
of a Purchase Plan Option or to receive shares of Common Stock under the
Purchase Plan may be assigned, transferred, pledged or otherwise disposed of
in any way (other than by will, the laws of descent and distribution, or by
designation of a beneficiary as provided in the Purchase Plan). Any such
attempt at assignment, transfer, pledge or other disposition will have no
effect, except that the Company may treat such act as an election to withdraw
funds, in which case the provisions described below under the heading
"Withdrawal and Termination of Employment" will apply.
 
  Withdrawal and Termination of Employment. A Participant may terminate
participation in the Purchase Plan and withdraw all, but not less than all, of
the payroll deductions credited to the Participant's account under the
Purchase Plan at any time prior to the Termination Date of an Offering, by
giving written notice to the Company. The notice must state the Participant's
desire to terminate involvement in the Purchase Plan, specify a termination
date and request the withdrawal of all of the Participant's payroll deductions
held under the Purchase Plan. All of the Participant's payroll deductions
credited to the Participant's account will be paid to such Participant as soon
as practicable after the termination date specified in the notice (or, if no
date is specified, as soon as practicable after receipt of the notice of
termination and withdrawal), and the Purchase Plan Option for the current
Offering Period will automatically be canceled, and no further payroll
deductions for the purchase of shares of Common Stock will be made during the
Offering Period or for any subsequent Offering Period unless a new
participation form is filed. A Participant's withdrawal from an Offering will
not have any effect upon the Participant's eligibility to participate in a
succeeding Offering or in any similar plan which the Company may adopt.
 
  Upon termination of a Participant's employment prior to the last day of an
Offering Period for any reason, including retirement or death, the payroll
deductions credited to such Participant's account will be returned as soon as
practicable after such termination to such Participant or, in the case of the
Participant's death, to the person or persons entitled to such funds in
accordance with the provisions described above under the section "Non-
Transferability of Purchase Plan Options," and the Participant's Purchase Plan
Option will be automatically canceled. A transfer of employment between the
Company and a subsidiary or between subsidiaries and absences or leaves
approved by the Company are not considered terminations under the Purchase
Plan.
 
  Upon withdrawal and termination of a Participant's participation in the
Purchase Plan or termination of employment, the Participant will be entitled
to receive, at the Participant's option, (i) cash equal to the Fair Market
Value of all full shares of Common Stock and any fractional share deemed
purchased and then held for the benefit of the Participant; or (ii) a
certificate representing the number of full shares of Common Stock held for
the benefit of the Participant plus cash in an amount equal to the Fair Market
Value of any remaining fractional shares deemed to have been purchased. For
purposes of withdrawal from the Purchase Plan or termination of employment,
"Fair Market Value" means the prevailing market price of the Common Stock as
reported by the Nasdaq National Market on the first day on which shares of
Common Stock are traded following the day on which Norwest receives notice
from a Participant of an event of withdrawal or termination. If a Participant
elects to receive cash, such Participant will be required to pay Norwest's
customary commission and sale transaction fees related to the sale of shares
owned by such Participant.
 
FEDERAL INCOME TAX CONSEQUENCES
 
  The following general description of federal income tax consequences is
based upon current statutes, regulations and interpretations. This description
is not intended to address specific tax
 
                                      17
<PAGE>
 
consequences applicable to an individual participant who receives a Purchase
Plan Option and does not address special rules that may be applicable to
directors and officers of the Company.
 
  The Purchase Plan is intended to qualify as an "employee stock purchase
plan" under Section 423 of the Internal Revenue Code of 1986, as amended (the
"Code"). If the Purchase Plan so qualifies, the amount withheld from a
Participant's compensation under the Purchase Plan will constitute ordinary
income for federal income tax purposes in the year in which such amounts would
otherwise have been paid to the Participant. However, a Participant will
generally not recognize any income for federal income tax purposes either on
the grant of a Purchase Plan Option or upon the issuance of any shares of
Common Stock under the Purchase Plan.
 
  The federal income tax consequences incurred upon disposition of shares of
Common Stock acquired under the Purchase Plan depend upon how long a
Participant holds the shares. If a Participant disposes of shares acquired
under the Purchase Plan (other than a transfer by reason of death) within a
period of two years from the Offering Date of the Offering in which the shares
were acquired, an amount equal to the difference between the purchase price
and the fair market value of the shares on the last day of the Offering Period
will be treated as ordinary income for federal income tax purposes in the
taxable year in which the disposition takes place. Such amount may be subject
to wage withholding. The difference between the amount realized upon such
disposition of the shares and their fair market value on the last day of the
Offering Period will constitute long-term capital gain or loss if the
disposition occurs more than one year after the last day of the Offering
Period and short-term capital gain or loss if the disposition occurs one year
or less after the last day of the Offering Period.
 
  If a Participant disposes of any shares acquired under the Purchase Plan
more than two years after the Offering Date of the Offering in which such
shares were acquired (or if no disposition has occurred by the time of
Participant's death) an amount equal to the lesser of (a) the excess of the
fair market value of the shares at the time of disposition (or death) over the
purchase price, or (b) the excess of the fair market value of the shares on
the Offering Date of the Offering in which the shares were acquired over the
purchase price will be recognized as ordinary income and may be subject to
wage withholding. With respect to a disposition of such shares, any remaining
gain on such disposition will be taxed as long-term capital gain. With respect
to a transfer of such shares upon death, any remaining gain or loss will not
be recognized. However, a subsequent sale or exchange of such shares by a
Participant's estate or the person receiving such shares by reason of the
Participant's death may result in capital gain or loss.
 
  No income tax deduction ordinarily is allowed to the Company with respect to
the grant of any Purchase Plan Option, the issuance of any shares of Common
Stock under the Purchase Plan or the disposition of any shares acquired under
the Purchase Plan and held for two years. However, if a Participant disposes
of shares purchased under the Purchase Plan within two years after the
Offering Date of the Offering in which the shares were acquired, the Company
will receive an income tax deduction in the year of such disposition in an
amount equal to the amount constituting ordinary income to the Participant,
provided that the Company complies with the applicable wage withholding
requirements.
 
BOARD OF DIRECTORS RECOMMENDATION
 
  The Board of Directors recommends that the stockholders vote FOR approval of
the Employee Stock Purchase Plan. The affirmative vote of the holders of a
majority of the shares of Common Stock present and entitled to vote in person
or by proxy on this matter at the Annual Meeting, and at least a majority of
the minimum number of votes necessary for a quorum, is necessary for approval.
Unless a contrary choice is specified, proxies solicited by the Board of
Directors will be voted FOR approval of the Employee Stock Purchase Plan.
 
                                      18
<PAGE>
 
                         RATIFICATION OF SELECTION OF
                             INDEPENDENT AUDITORS
 
                                  PROPOSAL 3
 
  The Board of Directors has appointed Ernst & Young LLP, independent
certified public accountants, as auditors of the Company for the year ending
December 31, 1997. Such firm has acted as independent auditors of the Company
since the fiscal year ended December 31, 1989. Although it is not required to
do so, the Board wishes to submit the selection of Ernst & Young LLP to the
stockholders for ratification. If the stockholders do not ratify the
appointment of Ernst & Young LLP, another firm of independent auditors will be
considered by the Board of Directors. Representatives of Ernst & Young LLP
will be present at the Annual Meeting, will have an opportunity to make a
statement if they so desire and will be available to respond to appropriate
questions.
 
BOARD OF DIRECTORS RECOMMENDATION
 
  The Board of Directors recommends a vote FOR ratification of the appointment
of Ernst & Young LLP as auditors of the Company for the year ending December
31, 1997. The affirmative vote of the holders of a majority of shares of
Common Stock of the Company present in person or by proxy at the Annual
Meeting, assuming a quorum is present, is necessary for approval. Unless a
contrary choice is specified, proxies solicited by the Board of Directors will
be voted FOR the ratification of Ernst & Young LLP.
 
            SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE
 
  Section 16(a) of the Securities Exchange Act of 1934, as amended, requires
the Company's directors and executive officers and all persons who
beneficially own more than 10% of the outstanding shares of the Company's
Common Stock to file with the Securities and Exchange Commission initial
reports of ownership and reports of changes in ownership of the Company's
Common Stock. Executive officers, directors and greater than 10% beneficial
owners are also required to furnish the Company with copies of all Section
16(a) forms they file. To the Company's knowledge, based upon a review of the
copies of such reports furnished to the Company during the year ended December
31, 1996 and written representations by such persons, none of the directors,
officers and beneficial owners of greater than 10% of the Company's Common
Stock failed to file on a timely basis the forms required by Section 16 of the
Exchange Act, except as follows: Gary A. Peterson failed to timely file a Form
4 with respect to the purchase by PSF Health Care Fund L.P. of 20,000 shares
of Common Stock in August 1996.
 
                 STOCKHOLDER PROPOSALS FOR 1998 ANNUAL MEETING
 
  Proposals of stockholders intended to be presented in the proxy materials
relating to the next Annual Meeting must be received by the Company at its
principal executive offices by December 4, 1997.
 
                                 OTHER MATTERS
 
  The management of the Company does not intend to present other items of
business and knows of no items of business that are likely to be brought
before the Annual Meeting except those described in this Proxy Statement.
However, if any other matters should properly come before the Annual Meeting,
the persons named in the enclosed proxy will have discretionary authority to
vote such proxy in accordance with the best judgment on such matters.
 
                                      19
<PAGE>
 
                                 MISCELLANEOUS
 
  THE COMPANY WILL FURNISH WITHOUT CHARGE A COPY OF ITS ANNUAL REPORT ON FORM
10-K (EXCLUSIVE OF EXHIBITS) FOR THE FISCAL YEAR ENDED DECEMBER 31, 1996 TO
EACH PERSON WHO WAS A STOCKHOLDER OF THE COMPANY AS OF MARCH 20, 1997, UPON
RECEIPT FROM ANY SUCH PERSON OF A WRITTEN REQUEST FOR SUCH AN ANNUAL REPORT.
SUCH REQUEST SHOULD BE SENT TO: OPTICAL SENSORS INCORPORATED, 7615 GOLDEN
TRIANGLE DRIVE, SUITE A, MINNEAPOLIS, MINNESOTA 55344; ATTN: STOCKHOLDER
INFORMATION.
 
                                          BY ORDER OF THE BOARD OF DIRECTORS
 
                                          LOGO
                                          Sam B. Humphries
                                          President and Chief Executive
                                          Officer
 
April 4, 1997
Minneapolis, Minnesota
 
                                      20
<PAGE>
 
                          OPTICAL SENSORS INCORPORATED
                          EMPLOYEE STOCK PURCHASE PLAN
                         (As Adopted December 3, 1996)

1.  Purpose.  The purpose of this Employee Stock Purchase Plan (the "Plan") is
to advance the interests of Optical Sensors Incorporated (the "Company") and its
shareholders by providing Employees of the Company and its Designated
Subsidiaries (as defined in Section 2(e) below) with an opportunity to acquire
an ownership interest in the Company through the purchase of Common Stock of the
Company on favorable terms through payroll deductions.  It is the intention of
the Company that the Plan qualify as an "employee stock purchase plan" under
Section 423 of the Internal Revenue Code of 1986, as amended (the "Code").
Accordingly, provisions of the Plan shall be construed so as to extend and limit
participation in a manner consistent with the requirements of Section 423 of the
Code.

2.  Definitions.

    (a)  "Board" means the Board of Directors of the Company.

    (b)  "Common Stock" means the common stock, par value $.01 per share, of the
    Company, or the number and kind of shares of stock or other securities into
    which such common stock may be changed in accordance with Section 13 of the
    Plan.

    (c)  "Committee" means the entity administering the Plan, as provided in
    Section 3 below.

    (d) "Compensation" means all earnings and commissions that are included in
    regular compensation, excluding bonuses (except to the extent that the
    inclusion of any such item is specifically directed by the Committee),
    determined in a manner consistent with the requirements of Section 423 of
    the Code, as provided in Section 1 above.

    (e)  "Designated Subsidiary" means a Subsidiary that has been designated by
    the Board from time to time, in its sole discretion, as eligible to
    participate in the Plan.

    (f)  "Employee" means any person, including an officer, who is employed by
    the Company or one of its Designated Subsidiaries, exclusive of any
    such person whose customary employment with the Company or a Designated
    Subsidiary is for 20 hours or less per week.

    (g)  "Exchange Act" means the Securities Exchange Act of 1934, as amended.

    (h)  "Fair Market Value" means, with respect to the Common Stock, as of any
    date:

         (i)   if the Common Stock is listed or admitted to unlisted trading
         privileges on any national securities exchange or is not so listed or
         admitted but transactions in the Common Stock are reported on the
         Nasdaq National Market, the closing sale price of the Common Stock on
         such exchange or by the Nasdaq National Market as of such date, rounded
         up to the next highest full cent (or, if no shares were traded on such
         day, as of the next preceding day on which there was such a trade); or

         (ii)  if the Common Stock is not so listed or admitted to unlisted
         trading privileges or reported on the Nasdaq National Market System,
         and bid and asked prices therefor in the over-the-counter market are
         reported by the Nasdaq SmallCap System or the National

                                       1
<PAGE>
 
         Quotation Bureau, Inc. (or any comparable reporting service), the
         average of the closing bid and asked prices as of such date, rounded up
         to the next highest full cent (or, if no shares were traded on such
         day, as of the next preceding day on which there was such a trade), as
         so reported by the Nasdaq SmallCap System, or, if not so reported
         thereon, as reported by the National Quotation Bureau, Inc. (or such
         comparable reporting service); or

         (iii) if the Common Stock is not so listed or admitted to unlisted
         trading privileges, or reported on the Nasdaq National Market System,
         and such bid and asked prices are not so reported, such price as the
         Committee determines in its sole discretion, but in a manner acceptable
         under Section 423 of the Code. (i) "Offering" means any of the
         offerings to Participants of options to purchase Common Stock under the
         Plan, each continuing for three months, except for the initial Offering
         which shall continue for four months, as described in Section 5 below.

    (j)  "Offering Date" means the first day of the Offering Period under the
    Plan, as described in Section 5 below.

    (k)  "Offering Period" means the time period commencing on the Offering Date
    and ending on the Termination Date.

    (l)  "Option Price" is defined in Section 8 below.

    (m)  "Participant" means an eligible Employee who elects to participate in
    the Plan pursuant to Section 6 below.

    (n)  "Securities Act" means the Securities Act of 1933, as amended.

    (o)  "Subsidiary" means any subsidiary corporation of the Company within the
    meaning of Section 424(f) of the Code.

    (p)  "Termination Date" means the last day of the Offering Period under the
    Plan, as described in Section 5 below.

3.  Administration.  So long as the Company has a class of its equity securities
registered under Section 12 of the Exchange Act, the Plan will be administered
by either the Board or if the Board determines, in its sole discretion, by a
committee of the Board consisting solely of not less than two members of the
Board who are "non-employee directors" within the meaning of Rule 16b-3 under
the Exchange Act.  Members of such a committee shall be appointed from time to
time by the Board, shall serve at the pleasure of the Board, and may resign at
any time upon written notice to the Board.  A majority of the members of such a
committee shall constitute a quorum.  Such a committee shall act by majority
approval of the members and shall keep minutes of its meetings.  Action of such
a committee may be taken without a meeting if unanimous written consent is
given.  Copies of minutes of such a committee's meetings and of its actions by
written consent shall be kept with the corporate records of the Company.  As
used in this Plan, the term "Committee" will refer to such committee.  In
accordance with and subject to the provisions of the Plan, the Committee shall
have authority to make, administer and interpret such rules and regulations as
it deems necessary to administer the Plan, and any determination, decision or
action in connection with construction, interpretation, administration or
application of the Plan shall be final, conclusive and binding upon all
Participants and any and all persons claiming under or through any Participant.
No member of the 

                                       2
<PAGE>
 
Committee shall be liable for any action or determination made in good faith
with respect to the Plan or any option granted under the Plan.

4.  Eligibility.

    (a)  Any Employee who is employed by the Company or a Designated Subsidiary
    on the date that this Plan is approved by the Board and any Employee who
    becomes an employee after such date and has been employed by the Company or
    a Designated Subsidiary for at least one month prior to an Offering Date
    shall be eligible to participate in the Plan, beginning with the Offering
    commencing on such Offering Date, subject to the limitations imposed by
    Section 423(b) of the Code. With respect to a Designated Subsidiary that has
    been acquired by the Company, the period of employment of Employees of such
    Designated Subsidiary occurring prior to the time of such acquisition shall
    be included for purposes of determining whether an Employee has been
    employed for the requisite period of time under the Plan.
    
    (b)  Any provisions of the Plan to the contrary notwithstanding, no Employee
    shall be granted an option under the Plan if:

         (i)   immediately after the grant, such Employee (or any other person
         whose stock ownership would be attributed to such Employee pursuant to
         Section 424(d) of the Code) would own shares of Common Stock and/or
         hold outstanding options to purchase shares of Common Stock possessing
         five percent (5%) or more of the total combined voting power or value
         of all classes of shares of the Company or of any Subsidiary; or

         (ii)  the amount of payroll deductions that the Employee has elected to
         have withheld under such option (pursuant to Section 7 below) would
         permit the Employee to purchase shares of Common Stock under all
         "employee stock purchase plans" (within the meaning of Section 423 of
         the Code) of the Company and its Subsidiaries to accrue (i.e., become
         exercisable) at a rate that exceeds $25,000 of the Fair Market Value of
         such shares of Common Stock (determined at the time such option is
         granted) for each calendar year in which such option is outstanding at
         any time.

5.  Offerings.  Options to purchase shares of Common Stock shall be offered to
Participants under the Plan through a continuous series of Offerings, each
continuing for three months except for the initial Offering Period, and each of
which shall commence on February 1, May 1, August 1 and November 1 of each year,
as the case may be, except for the initial Offering Period (the "Offering
Date"), and shall terminate on April 30, July 31, October 31 and January 31 of
each year, as the case may be (the "Termination Date").  The first Offering
under the Plan shall have an Offering Date of January 1, 1997 and a Termination
Date of April 30, 1997.  Offerings under the Plan shall continue until either
(a) the Committee decides, in its sole discretion, that no further Offerings
shall be made because the Common Stock remaining available under the Plan is
insufficient to make an Offering to all eligible Employees, or (b) the Plan is
terminated in accordance with Section 17 below.

6.  Participation.

    (a)  An eligible Employee may become a Participant in the Plan by completing
    a subscription agreement authorizing payroll deductions on the form provided
    by the Company (the "Participation Form") and filing the Participation Form
    with the Company's Human Resources Department not 

                                       3
<PAGE>
 
    less than 15 days before the Offering Date of the first Offering in which
    the Participant wishes to participate.

    (b)  Except as provided in Section 7(a) below, payroll deductions for a
    Participant shall begin with the first payroll following the applicable
    Offering Date, and shall continue until the termination date of the Plan,
    subject to earlier termination by the Participant as provided in Section 11
    below or increases or decreases by the Participant in the amount of payroll
    deductions as provided in Section 7(c) below.

    (c)  A Participant may discontinue participation in the Plan at any time as
    provided in Section 11 below.

7.  Payroll Deductions.

    (a)  By completing and filing a Participation Form, a Participant shall 
    elect to have payroll deductions made from the Participant's total
    Compensation (in whole percentages from one percent (1%) to a maximum of ten
    percent (10%) of the Participant's total Compensation) on each payday during
    the time he or she is a Participant in the Plan in such amount as he or she
    shall designate on the Participation Form; provided, however, that no
    Participant's payroll deductions shall be less than $10.00 per pay period.

    (b)  All payroll deductions authorized by a Participant shall be credited to
    an account established under the Plan for the Participant. The monies
    represented by such account shall be held as part of the Company's general
    assets, usable for any corporate purpose, and the Company shall not be
    obligated to segregate such monies. A Participant may not make any separate
    cash payment or contribution to such account.

    (c)  No increases or decreases of the amount of payroll deductions for a
    Participant may be made during an Offering. A Participant may increase or
    decrease the amount of payroll deductions under the Plan for subsequent
    Offerings by completing an amended Participation Form and filing it with the
    Company's Human Resources Department not less than 15 days prior to the
    Offering Date as of which such increase or decrease is to be effective.

8.  Grant of Option.  On each Offering Date, each eligible Employee who is then
a Participant shall be granted (by operation of the Plan) an option to purchase
(at the Option Price) as many shares of Common Stock as the Participant will be
able to purchase with the payroll deductions credited to the Participant's
account during the Offering Period.  Notwithstanding the foregoing, in no event
may the number of shares purchased by any Employee during an Offering exceed
1,500 shares of Common Stock.  The option price per share of such shares (the
"Option Price") shall be the lesser of (a) eighty-five percent (85%) of the Fair
Market Value of one share of Common Stock on the Offering Date, or (b) eighty-
five (85%) of the Fair Market Value of one share of Common Stock on the
Termination Date.

9.  Exercise of Option.

    (a)  Unless a Participant gives written notice to the Company as provided in
    Section 9(d) below or withdraws from the Plan pursuant to Section 11 below,
    the Participant's option for the purchase of shares of Common Stock granted
    for an Offering will be exercised automatically at the Termination Date of
    such Offering for the purchase of the number of full shares of Common Stock

                                       4
<PAGE>
 
    that the accumulated payroll deductions in the Participant's account on such
    Termination Date will purchase at the applicable Option Price.

    (b)  A Participant may purchase one or more shares in connection with the
    automatic exercise of an option granted for any Offering. If the Committee
    elects to deliver a statement of account to Participants pursuant to Section
    10(a)(i)(A) below, that portion of any balance remaining in a Participant's
    payroll deduction account at the close of business on the Termination Date
    of any Offering that is less than the purchase price of one full share will
    be deemed to have purchased such number of fractional shares of Common Stock
    as would then be purchasable at the applicable Option Price, with such
    fractional shares calculated to the third (3rd) decimal place. If the
    Committee elects to deliver stock certificates to Participants pursuant to
    Section 10(a)(i)(B) below, that portion of any balance remaining in a
    Participant's payroll deduction account at the close of business on the
    Termination Date of any Offering that is less than the purchase price of one
    full share will be carried forward into the Participant's payroll deduction
    account for the following Offering; provided that in no event will the
    balance carried forward be equal to or greater than the purchase price of
    one share on the Termination Date of an Offering.

    (c)  No Participant (or any person claiming through such Participant) shall
    have any interest in any Common Stock subject to an option under the Plan
    until such option has been exercised, at which point such interest shall be
    limited to the interest of a purchaser of the Common Stock purchased upon
    such exercise pending the delivery or credit of such Common Stock in
    accordance with Section 10 below. During the Participant's lifetime, a
    Participant's option to purchase shares of Common Stock under the Plan is
    exercisable only by such Participant.

    (d)  By written notice to the Company prior to the Termination Date of any
    Offering, a Participant may elect, effective on such Termination Date, to:

         (i)   withdraw all of the accumulated payroll deductions in the
         Participant's account as of the Termination Date (which withdrawal may,
         but need not, also constitute a notice of termination and withdrawal
         pursuant to Section 11(a)); or

         (ii)  exercise the Participant's option for a specified number of 
         full shares not less than five that is less than the number of full
         shares of Common Stock that the accumulated payroll deductions in the
         Participant's account will purchase on the Termination Date of the
         Offering at the applicable Option Price, and withdraw the balance in
         the Participant's payroll deduction account.

10. Delivery.

    (a)  As promptly as practicable after the Termination Date of each 
         Offering, the Company will deliver to each Participant, as appropriate,
         the following:

         (i)   At the election of the Committee, either issue (A) in 
         certificated or uncertificated form to a third party the aggregate
         number of shares of Common Stock purchased in connection with an
         Offering (including an aggregate of all of the fractional shares deemed
         to have been purchased pursuant to Section 9(b) above) rounded to the
         nearest full share, which shares will be held by such third party for
         the benefit of the Participants in accordance with their respective
         interests, and to each Participant a statement summarizing the number
         of whole shares of Common Stock purchased and fractional shares deemed

                                       5
<PAGE>
 
         purchased upon exercise of the Participant's option granted for such
         Offering, or (B) a certificate representing the number of full shares
         of Common Stock purchased upon exercise of the Participant's option
         granted for such Offering, registered in the name of the Participant
         or, if the Participant so directs on the Participation Form, in the
         names of the Participant and his or her spouse.

         (ii)  If the Participant makes an election pursuant to Section 9(d)(i)
         above for the Offering, a check in an amount equal to the total of the
         payroll deductions credited to the Participant's account.

         (iii)  If Participant makes an election pursuant to Section 9(d)(ii) 
         above, a check in the amount of the balance of any payroll deductions
         credited to the Participant's account that were not used for the
         purchase of Common Stock. (iv) If the balance in the Participant's
         payroll deduction account exceeds the dollar amount necessary to
         purchase the maximum amount of shares that may be purchased in an
         Offering, a check in an amount equal to the excess balance.

    (b)  If the Company delivers a statement of account as provided in Section
    10(a)(i)(A) above, a Participant may at any time request that a certificate
    for the number of whole shares of Common Stock purchased by such Participant
    in an Offering or in any previous Offering (with respect to which such
    participant has not been issued a certificate) be issued and delivered to
    such Participant by making a written request to the Company. Such written
    request shall be made to the Company's Human Resources Department or, at the
    direction of the Company, to the transfer agent and registrar for the
    Company's Common Stock. In lieu of issuing certificates for fractional
    shares, Participants will receive a cash distribution representing any
    fractional shares, calculated in accordance with Section 11(a) below.

    (c)  If the Company delivers a statement of account as provided in Section
    10(a)(i)(A) above, all full shares purchased and fractional shares deemed to
    have been purchased by a Participant in an Offering and in any subsequent
    Offerings will accumulate for the benefit of the Participant until the
    Participant's withdrawal or termination pursuant to Section 11 below.

11. Withdrawal; Termination of Employment.

    (a)  A Participant may terminate participation in the Plan and withdraw 
    all, but not less than all, of the payroll deductions credited to the
    Participant's account under the Plan at any time prior to the Termination
    Date of an Offering, for such Offering, by giving written notice to the
    Company. Such notice shall state that the Participant wishes to terminate
    the Participant's involvement in the Plan, specify a termination date and
    request the withdrawal of all of the Participant's payroll deductions held
    under the Plan. All of the Participant's payroll deductions credited to the
    Participant's account will be paid to such participant as soon as
    practicable after the termination date specified in the notice of
    termination and withdrawal (or, if no such date is specified, as soon as
    practical after receipt of notice of termination and withdrawal), and the
    Participant's option for such Offering will be automatically canceled, and
    no further payroll deductions for the purchase of shares of Common Stock
    will be made for such Offering or for any subsequent Offering, except in
    accordance with a new Participation Form filed pursuant to Section 6 above.
    If the Committee elects to deliver a statement of account pursuant to
    Section 10(a)(i)(A) above, then on the withdrawal and termination of a
    Participant's participation in the Plan, the

                                       6
<PAGE>
 
    Participant will be entitled to receive, at the Participant's option, (i)
    cash equal to the Fair Market Value of all full shares of Common Stock and
    any fractional share deemed purchased pursuant to Section 9(b) then held for
    the benefit of the Participant; or (ii) a certificate representing the
    number of full shares of Common Stock held for the benefit of the
    Participant plus cash in an amount equal to the Fair Market Value of any
    remaining fractional shares deemed to have been purchased. In any event,
    Fair Market Value will be determined as set forth in Section 11(d) below,
    and such certificate will be delivered and such amounts paid as soon
    thereafter as practicable.

    (b)  Upon termination of a Participant's employment for any reason, 
    including retirement or death, the payroll deductions accumulated in the
    Participant's account will be returned to the Participant as soon as
    practicable after such termination or, in the case of death, to the person
    or persons entitled thereto under Section 14 below, and the Participant's
    option will be automatically canceled. If the Committee elects to deliver a
    statement of account pursuant to Section 10(a)(i)(A), then upon the
    termination of a Participant's employment for any reason, including
    retirement or death, the Participant, or, in the case of death, the
    Participant's Designated Beneficiary (if allowed by the Committee) or the
    executor or administrator of the Participant's estate will be entitled to
    receive, at their option, (i) cash equal to the Fair Market Value of all
    full shares of Common Stock and any fractional share deemed purchased
    pursuant to Section 9(b) then held for the benefit of the Participant; or
    (ii) a certificate representing the number of full shares of Common Stock
    held for the benefit of the Participant plus cash in an amount equal to the
    Fair Market Value of any remaining fractional share deemed to have been
    purchased. In any event, Fair Market Value will be determined as set forth
    in Section 11(d) below and such certificate will be delivered and such
    amounts paid as soon thereafter as practicable. For purposes of the Plan,
    the termination date of employment shall be the Participant's last date of
    actual employment and shall not include any period during which such
    Participant receives any severance payments. A transfer of employment
    between the Company and a Designated Subsidiary or between one Designated
    Subsidiary and another Designated Subsidiary, or absence or leave approved
    by the Company, shall not be deemed a termination of employment under this
    Section 11(b).

    (c)  A Participant's termination and withdrawal pursuant to Section 11(a) 
    above will not have any effect upon the Participant's eligibility to
    participate in a subsequent Offering by completing and filing a new
    Participation Form pursuant to Section 6 above or in any similar plan that
    may hereafter be adopted by the Company.

    (d)  For purposes of this Section 11 only, "Fair Market Value" means the
    prevailing market price of the Common Stock on any national securities
    exchange (if the Common Stock is listed on any such exchange) or as reported
    by the Nasdaq National Market, the Nasdaq SmallCap System or the National
    Quotation Bureau, Inc. (or any comparable reporting service), as the case
    may be, (if transactions or bid and asked prices are reported in the over-
    the-counter market are so reported) on the first day on which shares of
    Common Stock are traded following the day on which the Company, or if the
    Company so designates, the Company's agent, receives notice from a
    Participant of an event specified in Section 11(a) or 11(b) above.

12. Interest.  No interest shall accrue on a Participant's payroll deductions
under the Plan.

13. Stock Subject to the Plan.

    (a)  The maximum number of shares of Common Stock that shall be reserved for
    sale under the Plan shall be 200,000 shares, subject to adjustment upon
    changes in capitalization of the Company 

                                       7
<PAGE>
 
    as provided in Section 13(b) below. The shares to be sold to Participants
    under the Plan may be, at the election of the Company, either treasury
    shares or shares authorized but unissued. If the total number of shares of
    Common Stock that would otherwise be subject to options granted pursuant to
    Section 8 above on any Termination Date exceeds the number of shares then
    available under the Plan (after deduction of all shares for which options
    have been exercised or are then outstanding), the Company shall make a pro
    rata allocation of the shares of Common Stock remaining available for
    issuance in as uniform and equitable a manner as is practicable as
    determined in the Company's sole discretion. In such event, the Company
    shall give written notice of such reduction of the number of shares subject
    to the option to each Participant affected thereby and shall return any
    excess funds accumulated in each Participant's account as soon as
    practicable after the Termination Date of such Offering.

    (b)  If any option under the Plan is exercised after any Common Stock 
    dividend, split-up, recapitalization, merger, consolidation, combination or
    exchange of Common Stock or the like, occurring after the shareholders of
    the Company approve the Plan, the number of shares of Common Stock to which
    such option shall be applicable and the Option Price for such Common Stock
    shall be appropriately adjusted by the Company.

    (c)  In the event that Participants are deemed to have purchased fractional
    shares of Common Stock pursuant to Section 9(b) above, the aggregate of such
    fractional share interests at any given time will be applied to reduce the
    maximum number of shares of Common Stock remaining available for issuance
    under the Plan.

14. Designation of Beneficiary.

    (a)  In the discretion of the Committee, a Participant may file written
    designation of a beneficiary who is to receive shares of Common Stock and/or
    cash, if any, from the Participant's account under the Plan in the event of
    such Participant's death at a time when cash or shares of Common Stock are
    held for the Participant's account.

    (b)  Such designation of beneficiary may be changed by the Participant at 
    any time by written notice. In the event of the death of a Participant in
    the absence of a valid designation of a beneficiary who is living at the
    time of such Participant's death, the Company shall deliver such shares of
    Common Stock and/or cash to the executor or administrator of the estate of
    the Participant; or, if no such executor or administrator has been appointed
    (to the knowledge of the Company), the Company, in its discretion, may
    deliver such shares of Common Stock and/or cash to the spouse or to any one
    or more dependents or relatives of the Participant; or, if no spouse,
    dependent or relative is known to the Company, then to such other person as
    the Company may designate.

15. Transferability.  Neither payroll deductions credited to a Participant's
account nor any rights with regard to the exercise of an option or to receive
shares of Common Stock under the Plan may be assigned, transferred, pledged or
otherwise disposed of in any way (other than by will, the laws of descent and
distribution, or as provided in Section 14 above) by the Participant.  Any such
attempt at assignment, transfer, pledge or other disposition shall be without
effect, except that the Company may treat such act as an election to withdraw
funds in accordance with Section 11(a) above.

                                       8
<PAGE>
 
16. Share Transfer Restrictions.

    (a)  Shares of Common Stock shall not be issued under the Plan unless such
    issuance is either registered under the Securities Act and applicable state
    securities laws or is exempt from such registrations.

    (b)  Shares of Common Stock issued under the Plan may not be sold, assigned,
    transferred, pledged, encumbered, or otherwise disposed of (whether
    voluntarily or involuntarily) except pursuant to registration under the
    Securities Act and applicable state securities laws, or pursuant to
    exemptions from such registrations.

17. Amendment or Termination.  The Plan may be amended by the Board from time
to time to the extent that the Board deems necessary or appropriate in light of,
and consistent with, Section 423 of the Code; provided, however, that no such
amendment shall be effective, without approval of the shareholders of the
Company, if shareholder approval of the amendment is then required pursuant to
Rule 16b-3 under the Exchange Act or any successor rule or Section 423 of the
Code.  The Board also may terminate the Plan or the granting of options pursuant
to the Plan at any time; provided, however, that the Board shall not have the
right to modify, cancel, or amend any outstanding option granted pursuant to the
Plan before such termination unless each Participant consents in writing to such
modification, amendment or cancellation.

18. Notices.  All notices or other communications by a Participant to the
Company in connection with the Plan shall be deemed to have been duly given when
received in the Company' Human Resources Department or in such other department
or by such other person as may be designated by the Company for the receipt of
such notices or other communications, in the form and at the location specified
by the Company.

19. Effective Date of Plan.  The Plan shall be effective as of December 3,
1996, the date the Plan was adopted by the Board.  The Plan has been adopted by
the Board subject to shareholder approval, and prior to shareholder approval
shares of Common Stock may be issued under the Plan subject to such approval.

20. Miscellaneous.  The headings to Sections in the Plan have been included for
convenience of reference only.  Except as otherwise expressly indicated, all
references to Sections in the Plan shall be to Sections of the Plan.  The Plan
shall be interpreted and construed in accordance with the laws of the State of
Delaware.

                                       9
<PAGE>
 
                          Optical Sensors Incorporated
                          EMPLOYEE STOCK PURCHASE PLAN

        PAYROLL DEDUCTION AUTHORIZATION FORM AND SUBSCRIPTION AGREEMENT


______    Original Application
______    Change in Payroll Deduction Amount

1.  I, _______________________________ hereby elect to participate in the
    Optical Sensors Incorporated Employee Stock Purchase Plan (the "Plan") and
    subscribe to purchase shares of the Company's Common Stock (the "Shares") in
    accordance with this Agreement and the Plan.

2.  I hereby authorize payroll deductions, beginning ____________, 19__, from
    each paycheck in the amount of __% of my compensation (may not exceed ten
    percent (10%) of total compensation on each payday) in accordance with the
    Plan.

3.  I understand that said payroll deductions shall be accumulated for the
    purchase of shares in accordance with the Plan, and that shares will be
    purchased for me automatically at the end of each three-month Offering
    Period under the Plan (four months for the Offering Period beginning on
    January 1, 1997) unless I withdraw my accumulated payroll deductions,
    withdraw from the Plan, or both, by giving written notice to the Company
    prior to the end of the offering period, as provided in the Plan.

4.  Shares purchased for me under the Plan should be issued or held in an
    account in the name(s) of:


    ----------------------------------------------------------------------------
 
                                   (name(s))

 
    ----------------------------------------------------------------------------
                                   (address)
 
 
 
    ----------------------------------------------------------------------------
                            (social security number)
 

5.  I understand that if I dispose of any Shares received by me pursuant to the
Plan within two years after the first day of the Offering Period during which I
purchased such Shares, I may be treated for federal income tax purposes as
having received ordinary income at the time of such disposition in an amount
equal to the excess of the fair market value of the Shares at the time such
Shares were delivered to me over the option price paid for the Shares.  I hereby
agree to notify the Company in writing within 30 days after the date of any such
disposition.  However, if I dispose of such shares at any time after the
expiration of the two-year holding period, I understand that I will be treated
for federal income tax purposes as having received income only at the time of
such disposition, and that such income will be taxed as ordinary income only to
the extent of an amount equal to the lesser of (a) the excess of the fair market
value of the Shares at the time of such disposition over the amount paid for the
Shares under the option, or (b) the excess of the fair market value of the
Shares over the option price, measured as if the option had been exercised 
on the 
<PAGE>
 
first day of the offering period during which I purchased such shares.  The
remainder of the gain, if any, recognized on such disposition will be taxed at
capital gains rates.

6.  I have read the current prospectus for the Optical Sensors Incorporated
Employee Stock Purchase Plan.


Date:
       -----------------------      ------------------------------------------
                                              Signature of Employee         



CERTIFICATION OF TAX IDENTIFICATION NUMBER


- ------------------------------------------------------------------------------ 
Please indicate your Social Security or Tax Identification Number

I certify under penalties of perjury (1) that the number above is my correct
Social Security or Taxpayer Identification Number and (2) that I am not subject
to backup withholding either because I have not been notified by the IRS that I
am subject to backup withholding as a result of failure to report all interest
or dividends, or the IRS has notified me that I am no longer subject to backup
withholding.


Date:
       -----------------------      ------------------------------------------
                                              Signature of Employee         
<PAGE>

- --------------------------------------------------------------------------------

PROXY

                          OPTICAL SENSORS INCORPORATED
          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

  The undersigned hereby appoints Sam B. Humphries and Wesley G. Peterson, and
each of them, as Proxies, each with full power to appoint his substitute, and
hereby authorizes each of them to represent and to vote, as designated below,
all the shares of Common Stock of Optical Sensors Incorporated held of record
by the undersigned on March 20, 1997, at the Annual Meeting of Stockholders to
be held on May 13, 1997, or any adjournment, thereof.

1. ELECTION OF DIRECTORS.

 [_] FOR all nominees listed below [_] AGAINST all nominees listed below
 (except as marked to the contrary below)

      Sam B. Humphries      Peter H. McNerney    Demetre M. Nicoloff, M.D.
      Promod Haque, Ph.D.   John M. Nehra        Gary A. Peterson

(INSTRUCTION: TO VOTE AGAINST ANY INDIVIDUAL NOMINEE, STRIKE A LINE THROUGH THE
                                NOMINEE'S NAME.)
 
2. Proposal to consider and act upon a proposal to approve the Company's
 Employee Stock Purchase Plan.
 
                         [_] FOR[_] AGAINST[_] ABSTAIN
 
3. Proposal to ratify the Appointment of Ernst & Young LLP as Independent
Auditors for the Company for the fiscal year ending December 31, 1997.
 
                         [_] FOR[_] AGAINST[_] ABSTAIN
 
4. In their discretion, the Proxies are authorized to vote upon such other
business as may properly come before the meeting.

- --------------------------------------------------------------------------------
 
- --------------------------------------------------------------------------------

  THIS PROXY, WHEN PROPERLY EXECUTED, WILL BE VOTED IN THE MANNER DIRECTED
HEREIN BY THE UNDERSIGNED SHAREHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL
BE VOTED FOR PROPOSALS 2 AND 3 AND FOR ALL NOMINEES NAMED IN PROPOSAL 1 ABOVE.
Please sign exactly as name appears below. When shares are held by joint
tenants, both should sign. When signing as attorney, executor, administrator,
trustee or guardian, please give full title as such. If a corporation, please
sign in full corporate name by President or other authorized officer. If a
partnership, please sign in partnership name by authorized person.
 
                                           Dated: ____________, 1997
 
                                           ------------------------------------
                                                   Signature
 
                                           ------------------------------------
                                               Signature if held
                                                    jointly
 
 PLEASE MARK, SIGN, DATE AND RETURN THE PROXY CARD PROMPTLY USING THE ENCLOSED
      ENVELOPE, WHICH REQUIRES NO POSTAGE IF MAILED IN THE UNITED STATES.
 
- --------------------------------------------------------------------------------


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