SUGEN INC
10-Q, 1997-05-14
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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================================================================================

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549
                          -----------------------------

                                    FORM 10-Q
(Mark one)

   X       Quarterly  report  pursuant  to Section 13 or 15(d) of the Securities
- -------    Exchange Act of 1934.  For the quarterly period ended March 31, 1997.
           or
           Transition  report  pursuant to Section 13 or 15(d) of the Securities
- -------    Exchange Act of 1934. For the transition  period from  ___________ to
           ___________.


                             Commission File Number:
                                     0-24814
                          -----------------------------


                                   SUGEN, Inc.
             (Exact name of registrant as specified in its charter)

                 Delaware                                    13-3629196
       (State or other jurisdiction of                    (I.R.S. Employer
       incorporation or organization)                     Identification No.)


               351 Galveston Drive, Redwood City, California 94063
                    (address of principal executive offices)

                                 (415) 306-7700
              (Registrant's telephone number, including area code)


                          -----------------------------



Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required to file such reports),  and (2) has been subject to filing requirements
for the past 90 days. Yes [X] No [ ]


Indicate the number of shares  outstanding  of each of the  issuer's  classes of
common stock, as of the latest  practicable  date.  Common Stock $.01 par value;
13,070,643 shares outstanding at April 30, 1997.


================================================================================

<PAGE>


                                   SUGEN, Inc.

                                      INDEX

                                                                        PAGE NO.
PART I.  FINANCIAL INFORMATION                                          --------

Item 1.           Financial Statements and Notes

                  Condensed Balance Sheets - March 31, 1997
                  and December 31, 1996                                     3

                  Statements of Operations - for the three months
                  ended March 31, 1997 and 1996                             4

                  Condensed Statements of Cash Flows - for the three
                  months ended March 31, 1997 and 1996                      5

                  Notes to Financial Statements                             6

Item 2.           Management's Discussion and Analysis of Financial
                  Condition and Results of Operations                       7


PART II. OTHER INFORMATION


Item 6.           Exhibits and Reports on Form 8-K                         10


Signatures                                                                 11


Exhibit Index                                                              12



                                        2


<PAGE>



                         PART I. FINANCIAL INFORMATION

Item 1.   FINANCIAL STATEMENTS AND NOTES

<TABLE>
                                  SUGEN, Inc.

                            CONDENSED BALANCE SHEETS
                                 (In thousands)
<CAPTION>


                                                        March 31,               December 31,
                                                          1997                       1996
                                                      --------------           --------------
ASSETS                                                 (unaudited)
Current assets:
<S>                                                   <C>                      <C>          
        Cash and cash equivalents                     $       13,395           $      24,852
        Short-term investments                                36,345                  31,482
        Accounts receivable                                      242                     264
        Prepaid expenses and other current assets                809                     468
                                                      --------------           -------------
                Total current assets                          50,791                  57,066
                                                                        
Property and equipment, net                                    4,322                   4,095
Other assets                                                     802                     775
                                                      --------------           -------------
                                                      $       55,915           $      61,936
                                                      ==============           =============
LIABILITIES AND STOCKHOLDERS' EQUITY 
Current liabilities:   
        Accounts payable                               $       2,138           $         852
        Accrued liabilities                                    6,602                   7,406
        Deferred contract revenue                                370                     375
        Capital lease obligations - current portion            2,044                   1,835
                                                      --------------           -------------
                Total current liabilities                     11,154                  10,468

Capital lease obligations - non-current portion                3,311                   2,938
 
Stockholders' equity: 
        Common stock                                         108,471                 108,120 
        Deferred compensation                                   (635)                   (710)
        Note receivable from stockholder                        (883)                   (883)
        Accumulated deficit                                  (65,503)                (57,997)
                                                      --------------           -------------
                Total stockholders' equity                    41,450                  48,530
                                                      --------------           -------------
                                                      $       55,915           $      61,936
                                                      ==============           =============

<FN>
                            See accompanying notes.
</FN>
</TABLE>
                                                                        
                                       3


<PAGE>




                                  SUGEN, Inc.
 
                            STATEMENTS OF OPERATIONS
                    (In thousands, except per share amounts)
                                   (unaudited)


                                                          Three Months Ended
                                                               March 31,  
                                                        -----------------------
                                                          1997           1996
                                                        --------       --------
Contract revenue (includes amounts from
   related party)                                       $  1,487       $  3,479

Costs and expenses
        Research and development                           8,006          6,615
        General and administrative                         1,478          1,380
                                                        --------       --------
           Total costs and expenses                        9,484          7,995
                                                        --------       --------

Operating loss                                            (7,997)        (4,516)

Other income and expenses:
        Interest income                                      693            690
        Interest expense                                    (170)          (180)
                                                        --------       --------
           Other income, net                                 523            510
                                                        --------       --------
Net loss                                                $ (7,474)      $ (4,006)
                                                        ========       ========

Net loss per share                                      $  (0.57)      $  (0.38)
                                                        ========       ========

Shares used in computing net loss
  per share                                               13,022         10,473
                                                        ========       ========

                            See accompanying notes.

                                        4




<PAGE>

<TABLE>
                                  SUGEN, Inc.
                                                                        
                       CONDENSED STATEMENTS OF CASH FLOWS
                Increase (decrease) in cash and cash equivalents
                                 (In thousands)
                                  (unaudited)
<CAPTION>

                                                                    Three Months Ended
                                                                        March 31,
                                                            --------------------------------
                                                                 1997               1996
                                                            -----------          -----------
Cash flows from operating activities
<S>                                                         <C>                  <C>         
Net loss                                                    $    (7,474)         $    (4,006)
Adjustments to reconcile net loss to net cash used in
        operating activities:         
        Depreciation and amortization                               739                  506
        Deferred revenue                                             (5)              (1,290)
        Changes in operating assets and liabilities:     
          Prepaid expenses and other current assets                (319)                (149)
          Other assets                                              (27)                (203)
          Accounts payable                                        1,286                  530
          Accrued liabilities                                      (804)                 869
                                                            -----------          -----------
Net cash used in operating activities                            (6,604)              (3,743)
                                                            -----------          -----------

Cash flows from investing activities
Sales/maturities (purchases) of short-term investments, net      (4,895)               4,556
Purchases of property and equipment                                (891)                (435)
                                                            -----------          -----------
Net cash provided by (used in) investing activities              (5,786)               4,121
                                                            -----------          -----------

Cash flows from financing activities
Proceeds from issuance of common stock, net                         351                   78
Repurchase of common stock                                           -                (2,698)
Proceeds from issuance of warrant                                    -                   200
Proceeds from lease financing of property and equipment           1,069                  332
Payments under capital lease obligations                           (487)                (323)
                                                            -----------          -----------
Net cash provided by (used in) financing activities                 933               (2,411)
                                                            -----------          -----------

Net decrease in cash and cash equivalents                       (11,457)              (2,033)
Cash and cash equivalents at beginning of period                 24,852                8,226
                                                            -----------          -----------
Cash and cash equivalents at end of period                  $    13,395          $     6,193
                                                            ===========          ===========


<FN>
                            See accompanying notes.
</FN>
</TABLE>

                                       5


<PAGE>



                                   SUGEN, Inc.

                          NOTES TO FINANCIAL STATEMENTS

                                   (Unaudited)


1.       Summary of Significant Accounting Policies

         Basis of Presentation

         The  financial  information  at March 31, 1997 and for the three months
         ended March 31, 1997 and 1996 is unaudited but includes all adjustments
         (consisting only of normal  recurring  adjustments)  which SUGEN,  Inc.
         (the "Company")  considers  necessary for the fair  presentation of the
         financial  position  at such date and the  operating  results  and cash
         flows  for  those  periods.   The  accompanying   condensed   financial
         statements should be read in conjunction with the financial  statements
         and notes thereto for the year ended  December 31, 1996 included in the
         Company's  Form 10-K.  The results of the Company's  operations for any
         interim  period are not  necessarily  indicative  of the results of the
         Company's operations for a full fiscal year.

         Change in Method of Computing Earnings Per Share

         In February  1997,  the  Financial  Accounting  Standards  Board (FASB)
         issued Statement of Financial  Accounting  Standards No. 128,  Earnings
         Per  Share.  Effective  December  31,  1997,  the  Company  will  adopt
         Statement of Financial  Accounting  Standards  No. 128,  "Earnings  Per
         Share." In accordance with the Statement, the Company would be required
         to change the method  currently used to compute  earnings per share and
         restate  all  prior  periods.  The  impact  of  Statement  128  on  the
         calculation  of basic and  dilutive  earnings  per share is expected to
         have no impact on the net loss per share to be presented at year end.


2.       Accrued Liabilities

         The components of accrued liabilities consist of the following:

                                                  March 31,        December 31,
                                                    1997               1996
                                                  --------           --------
                                                         (In thousands)

      Accrued research & development services     $  3,328           $  3,724
      Accrued compensation                             652                883
      Accrued professional fees                        735                524
      Other                                          1,887              2,275
                                                  --------           --------
                                                  $  6,602           $  7,406
                                                  ========           ========


                                        6



<PAGE>



                                   SUGEN, Inc.

Item 2.         MANAGEMENT'S DISCUSSION AND ANALYSIS
                OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS


     In addition to  historical  information  contained  herein,  the  following
discussion   contains   forward-looking   statements   that  involve  risks  and
uncertainties.  The Company's actual results could differ significantly from the
results discussed in the forward-looking statements. Factors that could cause or
contribute to such  differences  include the factors  discussed below as well as
the factors discussed in the Company's Form 10-K for the year ended December 31,
1996.  The  Company  undertakes  no  obligation  to release  the  results of any
revision to these forward-looking statements which may be made to reflect events
or circumstances occurring after the date hereof or to reflect the occurrence of
unanticipated events.


Overview

         SUGEN was founded in July 1991 to discover and develop  small  molecule
drugs that target specific cellular signal transduction pathways. These pathways
have been  implicated  in  diseases  such as cancer and  diabetes  as well as in
dermatologic,  immunologic,  cardiovascular  and neurologic  disorders.  Through
March 31,  1997,  all of the  Company's  revenue  has been  earned  pursuant  to
collaborations  with Zeneca Limited ("Zeneca"),  ASTA Medica  Aktiengesellschaft
("ASTA Medica"), Vision Pharmaceuticals L.P., an affiliate of Allergan, Inc. and
Allergan, Inc. (collectively  "Allergan") and Amgen Inc. ("Amgen").  The Company
intends to pursue its drug discovery programs independently and in collaboration
with established pharmaceutical companies.

         The  Company has not been  profitable  since  inception  and expects to
incur  substantial  losses  for the  foreseeable  future,  primarily  due to the
expansion of  preclinical  and clinical  development  activities  as more of its
proprietary  cancer-related  programs  progress toward and into the clinic.  The
Company expects that losses will fluctuate from quarter to quarter and that such
fluctuations may be substantial. As of March 31, 1997, the Company's accumulated
deficit was $65.5 million.


Results of Operations

         The  Company's  revenues  for the three months ended March 31, 1997 and
1996 were $1.5 million and $3.5  million,  respectively.  Revenues for the three
months  ended March 31, 1997  included  contract  revenue  from the Allergan and
Zeneca collaborations and contract services revenue earned under the ASTA Medica
collaboration  for  non-collaboration  work. 1996 revenues  included set-up fees
associated with the ASTA Medica  collaboration  and wind-down fees in connection
with  the  termination  of  the  Amgen  collaboration   agreement.  The  Company
recognizes revenue from set-up fees and wind-down fees as the related activities
are performed,  which is generally over a twelve-month  period or less.  Through
December 31, 1996,  the set-up and wind-down fees from the ASTA Medica and Amgen
collaborations,  respectively,  had been  fully  recognized  as  revenue.  Going
forward,  the Company will not recognize any additional  revenue under the Amgen
collaboration  and will  recognize  additional  revenue  under  the ASTA  Medica
collaboration only upon the achievement of specified milestones and for contract
services provided by ASTA Medica for  non-collaboration  work. As a result, 1997
contract  revenue will continue to be lower in 1996 in the absence of additional
collaboration  agreements  during the year.  The  Company is  actively  pursuing
additional  collaborations,  but no assurance  can be given as to the ability of
the Company to enter such collaborations on a timely basis or at all.

         Research and development  expenses for the three months ended March 31,
1997 and 1996 were $8.0  million and $6.6  million,  respectively.  The increase
during 1997 was primarily due to higher personnel  related costs associated with
the  expansion  of the  Company's  research  and  development  programs  and the
progression of clinical activities, including expanded Phase I


                                        7

<PAGE>

and Phase II studies of the Company's lead anti-cancer compound,  SU101, and the
initiation  of clinical  studies  under the  Company's  Psoriasis  program.  The
continued  advancement  of several  earlier stage programs  through  preclinical
development also contributed to higher expenses in 1997.

         General and  administrative  expenses  for the three months ended March
31, 1997 and 1996 were $1.5 million and $1.4 million,  respectively. The Company
expects that its general and  administrative  expenses will continue to increase
in order to support the Company's research and development efforts.

         Interest income for the three months ended March 31, 1997 and 1996 were
$693,000 and $690,000, respectively. The Company earned slightly higher interest
income,  despite the  decline in interest  rates from the same period last year,
due to higher  investment  balances  arising  primarily  from  issuances  of the
Company's  capital stock.  Interest expense for the three months ended March 31,
1997 and 1996 were $170,000 and $180,000, respectively. The decrease in interest
expense was primarily due to the scheduled  termination of some of the Company's
leases.  The Company  expects  that  interest  expense  will  increase in future
periods due to the continued  use of capital  lease  financing for equipment and
facility improvements.


Liquidity and Capital Resources

         The Company had cash, cash  equivalents  and short-term  investments of
approximately  $49.7 million at March 31, 1997 compared with approximately $56.3
million at December 31, 1996.  The decrease in cash and  investments  during the
three  months  ended  March 31, 1997 was  primarily  due to the net loss for the
quarter.

         Through March 31, 1997,  the Company's  principal  sources of financing
have been its initial and follow-on public offerings of Common Stock, placements
of the  Company's  Preferred  and  Common  Stock  and funds  received  under the
Company's corporate  collaborations.  The Company's current principal sources of
liquidity  are its research  and  development  collaborations  with ASTA Medica,
Zeneca and Allergan,  its cash, cash equivalents and short-term  investments and
capital  lease  financing.  In March  1997,  the Company  secured an  additional
capital  lease line in the amount of $3.5  million for the purchase of equipment
and  facilities  improvements.  At March 31,  1997,  the  Company had a combined
availability of $3.1 million under this new line and its preceding lease line.

         The Company has entered into license and  research  agreements  whereby
the Company funds research projects performed by others or in-licenses compounds
from third  parties.  Some of the  agreements  may  require  the Company to make
milestone and royalty payments.  Under these programs,  commitments for external
research  funding  are  approximately  $2.3  million in 1997.  A number of these
agreements expire in late 1997. However,  the Company anticipates renewing these
agreements which may increase future  commitments of the Company.  Most of these
commitments  are  cancelable  within a three to six month  period  and limit the
amounts  payable by the Company for sponsored  research under the programs after
notice of cancellation by the Company.

         From time to time,  the  Company  evaluates  potential  investments  in
complementary  businesses,  products or technologies.  Currently, the Company is
considering modest investments in such complementary businesses during 1997. The
Company  has no other  present  undertakings,  commitments  or  agreements  with
respect to investments in other businesses.

         Net  additions of equipment and  leasehold  improvements  for the three
months ended March 31, 1997 and 1996 were $891,000 and  $435,000,  respectively.
Capital  additions  during the first quarter of 1997 included the initial phases
of a limited  facility  expansion and the continued  investment in enhancing the
Company's laboratory capabilities. The Company expects that its


                                        8

<PAGE>

capital  additions for 1997 will be higher than that of the prior year primarily
due to anticipated facility improvements to its laboratory and office space. The
Company intends to fund future capital  expenditures  principally  through lease
financing  or other debt  arrangements.  Accordingly,  it is  expected  that the
Company's  capital lease obligations and related interest expense as well as its
depreciation expense will increase in future periods.

         The Company  estimates that its existing  capital  resources,  together
with facility and  equipment  financing,  anticipated  revenues from its current
collaborations and net income from investment activities,  will be sufficient to
fund its planned operations through 1998. The Company anticipates that the funds
from future collaborations will extend this time period.  However,  there can be
no  assurance  that the  Company  will  enter into any such  collaborations.  In
addition,  there  can be no  assurance  that the  underlying  assumed  levels of
revenue and expense will prove accurate.  Whether or not these assumptions prove
to be accurate, the Company will need to raise substantial additional capital to
fund its operations. The Company intends to seek such additional funding through
collaborative  arrangements,  public or private  equity or debt  financings  and
capital lease transactions;  however,  there can be no assurance that additional
financing will be available on acceptable  terms or at all. If additional  funds
are raised by issuing equity  securities,  further  dilution to stockholders may
result.  In addition,  in the event that additional  funds are obtained  through
arrangements  with  collaborative  partners,  such  arrangements may require the
Company to relinquish rights to certain of its technologies,  product candidates
or products that the Company would  otherwise  seek to develop or  commercialize
itself.  If  adequate  funds are not  available,  the Company may be required to
delay,  reduce  the  scope  of or  eliminate  one or  more  of its  research  or
development programs, which could have a material adverse effect on the Company.

         The Company is at an early stage of  development  and must be evaluated
in light of the  uncertainties  and  complications  present  in a  biotechnology
company.  The Company has been in existence only since 1991 and to date two drug
candidates  (SU101 and SU5271) have entered human clinical  testing.  To achieve
profitable  operations  on a  continuing  basis,  the  Company,  alone  or  with
collaborative  partners, must successfully develop,  manufacture,  introduce and
market its proposed  products.  Products,  if any,  resulting from the Company's
research and development programs are not expected to be commercially  available
for several years, even if they are developed successfully and proven to be safe
and effective.  Before obtaining regulatory clearance for the commercial sale of
any of its products  under  development,  the Company must  demonstrate  through
preclinical  studies and clinical trials that the potential  product is safe and
efficacious  for use in  humans  for each  target  indication.  The  failure  to
adequately  demonstrate  the safety and  efficacy  of a product  under  clinical
development could delay or prevent regulatory clearance of the potential product
and could have a material  adverse effect on the Company.  In addition,  many of
the  Company's  currently  proposed  products  are  subject to  development  and
licensing arrangements with the Company's collaborators.  Therefore, the Company
is dependent on the research and development efforts of these collaborators with
respect to some of its proposed  products  and is entitled  only to a portion of
the revenues,  if any, realized from the commercial sale of any of the potential
products covered by the  collaborations in many  jurisdictions.  The Company has
experienced  significant  operating  losses  since its  inception.  The  Company
expects  to incur  significant  operating  losses at least for the next  several
years and expects  cumulative  losses to increase as the Company's  research and
development efforts,  including  preclinical and clinical testing, are expanded.
All of the  Company's  revenues  to date  have  been  received  pursuant  to the
Company's  collaborations.  Should  the  Company  or its  collaborators  fail to
perform in accordance with the terms of any of their agreements,  any consequent
loss of revenue under the agreements could have a material adverse effect on the
Company's results of operations. The foregoing risks reflect the Company's early
stage of  development  and the nature of the  Company's  industry and  potential
products.  Also inherent at the Company's  stage of  development  are a range of
additional risks, including manufacturing  uncertainties,  the Company's lack of
sales  and  marketing   capabilities,   competition,   uncertainties   regarding
protection  of  patents  and  proprietary  rights,   government  regulation  and
uncertainties regarding pharmaceutical pricing and reimbursement.

                                        9

<PAGE>

                           PART II. OTHER INFORMATION



Item 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         None.

Item 6.  EXHIBITS AND REPORTS ON FORM 8-K

(a)      Exhibits

Exhibit Number                      Description
- --------------                     -------------
  3.1              Restated Certificate of Incorporation (2)
  3.2(ii)          Bylaws of the Registrant (1)
  3.3              Certificate of  Designation of Series A Junior  Participating
                   Preferred Stock of the Registrant (3)
  10.61+           Master Lease  Agreement,  dated March 28,  1997,  between the
                   Registrant and Transamerica Business Credit Corporation.
  10.62+           Lease  Financing  Commitment  Letter,  dated March 20,  1997,
                   between  the  Registrant  and  Transamerica  Business  Credit
                   Corporation.
  27               Financial Data Schedule


- --------------
   +            The Registrant has requested  confidential  treatment with 
                  respect to portions of this Exhibit.
  (1)           Incorporated by reference to identically  numbered  exhibits 
                  filed in response to Item 16 "Exhibits" of the  Company's  
                  Registration  Statement on Form S-1, as amended (File Number
                  33-77074), which became effective October 4, 1994.
  (2)           Incorporated by reference to identically  numbered  exhibits 
                  filed in response to Item 14 "Exhibits"  of the Company's 
                  Annual Report of Form 10-K for the year ended December 31,
                  1994.
  (3)           Filed as an  exhibit  to the Form 8-K  Current Report dated 
                  July 26,  1995 and incorporated herein by reference.


(b)      Reports on Form 8-K

         No reports on Form 8-K were filed  during the  quarter  ended March 31,
         1997.

                                       10



<PAGE>



                                   SUGEN, Inc.

                                   SIGNATURES


Date:   May 9, 1997                           SUGEN, Inc.




By:    /s/ Stephen Evans-Freke                By:   /s/ Christine E. Gray-Smith
       ----------------------------                 ---------------------------
       Stephen Evans-Freke                          Christine E. Gray-Smith
       Chairman and                                 Vice President, Finance
       Chief Executive Officer                      (Principal Financial and
                                                      Accounting Officer)


                                       11


<PAGE>

                                   SUGEN, Inc.

                                  EXHIBIT INDEX



Exhibit Number                      Description
- --------------                     -------------
  3.1              Restated Certificate of Incorporation (2)
  3.2(ii)          Bylaws of the Registrant (1)
  3.3              Certificate of  Designation of Series A Junior  Participating
                   Preferred Stock of the Registrant (3)
  10.61+           Master Lease  Agreement,  dated March 28,  1997,  between the
                   Registrant and Transamerica Business Credit Corporation.
  10.62+           Lease  Financing  Commitment  Letter,  dated March 20,  1997,
                   between  the  Registrant  and  Transamerica  Business  Credit
                   Corporation.
  27               Financial Data Schedule


- --------------
   +            The Registrant has requested  confidential  treatment with 
                  respect to portions of this Exhibit.
  (1)           Incorporated by reference to identically  numbered  exhibits 
                  filed in response to Item 16 "Exhibits" of the  Company's  
                  Registration  Statement on Form S-1, as amended (File Number
                  33-77074), which became effective October 4, 1994.
  (2)           Incorporated by reference to identically  numbered  exhibits 
                  filed in response to Item 14 "Exhibits"  of the Company's 
                  Annual Report of Form 10-K for the year ended December 31,
                  1994.
  (3)           Filed as an  exhibit  to the Form 8-K  Current Report dated 
                  July 26,  1995 and incorporated herein by reference.



                                       12





                                        *** TEXT OMITTED AND FILED SEPARATELY
                                            CONFIDENTIAL TREATMENT REQUESTED
                                            UNDER 17 C.F.R. SS.SS. 200.80(B)(4),
                                            200.83 AND 240.24B-2


                             MASTER LEASE AGREEMENT

Lessor:  TRANSAMERICA BUSINESS CREDIT CORPORATION
         Riverway II
         West Office Tower
         9399 West Higgins Road
         Rosemont, Illinois  60018

Lessee:  SUGEN, INC.
         351 Galveston Drive
         Redwood City, California 94063-4720

The lessor  pursuant to this Master Lease  Agreement  ("Agreement")  dated as of
March 28, 1997, is Transamerica  Business  Credit  Corporation  ("Lessor").  All
equipment,  software (Software),  items designated as tenant improvements on the
applicable schedule (Tenant  Improvements)  together with all present and future
additions, parts, accessories, attachments, substitutions, repairs, improvements
and  replacements  thereof  or  thereto,  which are the  subject  of a Lease (as
defined in the next sentence) shall be referred to as "Equipment."  Simultaneous
with the execution and delivery of this Agreement, the parties are entering into
one or more Lease Schedules (each, a "Schedule")  which refer to and incorporate
by reference this Agreement, each of which constitutes a lease (each, a "Lease")
for the Equipment specified therein. Additional details pertaining to each Lease
are  specified  in the  applicable  Schedule.  Each  Schedule  that the  parties
hereafter enter into shall constitute a Lease. Lessor has no obligation to enter
into any additional leases with, or extend any future financing to, Lessee other
than stated in Paragraph 1 below.


                 LEASE.  Subject to and upon all of the terms and conditions of
this Agreement and each Schedule,  Lessor hereby agrees to lease to Lessee up to
$3,500,000 in Equipment,  including up to [...***...] in Tenant Improvements and
up to  [...***...] in Software and Lessee hereby agrees to lease from Lessor the
Equipment for the Term (as defined in Paragraph 2 below) thereof.


<PAGE>


                  TERM. Each Lease shall be effective and the term of each Lease
("Term")  shall  commence on the  commencement  date specified in the applicable
Schedule which date shall not be prior to delivery,  acceptance and funding and,
unless sooner terminated (as hereinafter  provided),  shall expire at the end of
the term specified in such Schedule;  provided, however, that obligations due to
be  performed  by Lessee  during  the Term shall  continue  until they have been
performed  in full.  Schedules  will only be executed  after the delivery of the
Equipment to Lessee or upon  completion of deliveries of items of such Equipment
with aggregate cost of not less than [...***...].

                  RENT.  Lessee  shall  pay as  rent to  Lessor,  for use of the
Equipment  during the Term or Renewal Term (as defined in Paragraph  8),  rental
payments equal to the sum of all rental payments including,  without limitation,
security deposits, advance rents and interim rents payable in the amounts and on
the dates specified in the applicable  Schedule  ("Rent").  If any Rent or other
amount  payable by Lessee is not paid  within ten days after the day on which it
becomes payable, Lessee will pay on demand, as a late charge, an amount equal to
[...***...] or other amount but only to the extent  permitted by applicable law.
All  payments  provided  for herein  shall be  payable to Lessor at its  address
specified above, or at any other place designated by Lessor.  Lessees commitment
fee paid  pursuant to the  Commitment  Letter  dated March 20, 1997 (as amended,
supplemented or otherwise modified from time to time, the (Commitment  Letter)),
shall be applied  towards the second months rent (after  deductions for expenses
under paragraph 23) under the initial  Schedules and each monthly rental payment
thereafter until fully applied.

                  LEASE NOT CANCELABLE;  LESSEE'S OBLIGATIONS ABSOLUTE. No Lease
may be canceled or terminated  except as expressly  provided herein.  So long as
Lessor  has not  wrongfully  interfered  with  Lessees  quiet  enjoyment  of the
Equipment,  Lessee's  obligation  to pay all Rent due or to become due hereunder
shall be  absolute  and  unconditional  and shall not be  subject  to any delay,
reduction,   set-off,  defense,   counterclaim  or  recoupment  for  any  reason
whatsoever, including any failure of the Equipment or any representations by the
manufacturer or the vendor thereof.  If the Equipment is unsatisfactory  for any
reason,  Lessee  shall

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make any claim solely against the  manufacturer or the vendor thereof and shall,
nevertheless, pay Lessor all Rent payable hereunder.

                  SELECTION AND USE OF EQUIPMENT. Lessee agrees that it shall be
responsible for the selection,  use of, and results obtained from, the Equipment
and any other associated equipment or services.

                  WARRANTIES.   LESSOR  MAKES  NO  REPRESENTATION  OR  WARRANTY,
EXPRESS OR IMPLIED, AS TO ANY MATTER WHATSOEVER,  INCLUDING, WITHOUT LIMITATION,
THE DESIGN OR CONDITION OF THE  EQUIPMENT OR ITS  MERCHANTABILITY,  SUITABILITY,
QUALITY OR FITNESS  FOR A  PARTICULAR  PURPOSE,  AND HEREBY  DISCLAIMS  ANY SUCH
WARRANTY.  LESSEE  SPECIFICALLY WAIVES ALL RIGHTS TO MAKE A CLAIM AGAINST LESSOR
FOR BREACH OF ANY WARRANTY  WHATSOEVER.  ONCE ACCEPTED BY LESSEE,  LESSEE LEASES
THE  EQUIPMENT  "AS IS." IN NO EVENT SHALL  LESSOR HAVE ANY  LIABILITY  FOR, NOR
SHALL LESSEE HAVE ANY REMEDY  AGAINST LESSOR FOR, ANY  LIABILITY,  CLAIM,  LOSS,
DAMAGE  OR  EXPENSE  CAUSED  DIRECTLY  OR  INDIRECTLY  BY THE  EQUIPMENT  OR ANY
DEFICIENCY OR DEFECT THEREOF OR THE OPERATION,  MAINTENANCE OR REPAIR THEREOF OR
ANY CONSEQUENTIAL  DAMAGES AS THAT TERM IS USED IN SECTION 2-719(3) OF THE MODEL
UNIFORM COMMERCIAL CODE, AS AMENDED FROM TIME TO TIME ("UCC").  Lessor grants to
Lessee,  for the sole purpose of prosecuting a claim or receiving benefits under
the  warranty,  the  benefits of any and all  warranties  made  available by the
manufacturer or the vendor of the Equipment to the extent assignable.

                  DELIVERY.  Lessor hereby appoints Lessee as Lessor's agent for
the sole and limited  purpose of accepting  delivery of the Equipment  from each
vendor thereof.  Lessee shall pay any and all delivery and installation charges.
Lessor  shall not be liable to Lessee for any delay in, or failure of,  delivery
of the Equipment.

                  RENEWAL.  So long as no Event of Default or event which,  with
the giving of notice, the passage of time, or both, would constitute an Event of
Default,  shall have  occurred and be  continuing,  or the Lessee shall not have
exercised  its  purchase  option under  Paragraph 9 hereof,  Lessee may elect to
renew upon 60 days prior  written  notice to Lessor  each Lease on the terms and
conditions  of this  Agreement or as set forth in the

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applicable Schedule (the Renewal Term); provided, however, that if Lessee elects
to renew,  obligations due to be performed by the Lessee during the Renewal Term
shall  continue  until they have been  performed  in full.  The  monthly  rental
payments for the Renewal Term shall be as set forth in the applicable Schedule.

                  PURCHASE  OPTION.  So long as no  Event  of  Default  or event
which, with the giving of notice, the passage of time, or both, would constitute
an Event of Default, shall have occurred and be continuing,  Lessee may purchase
all, but not less than all, the Equipment covered by the applicable Lease on the
date  specified  therefor in the  applicable  Schedule  ("Purchase  Date").  The
purchase price for such Equipment shall be set forth in the applicable Schedule.
So long as no Event of Default or event  which,  with the giving of notice,  the
passage of time,  or both,  would  constitute  an Event of  Default,  shall have
occurred and be continuing,  Lessee may purchase all, but not less than all, the
Equipment  covered by the  applicable  Schedule  by the last date of the Renewal
Term (the "Alternative Purchase Date") at a purchase price equal to [...***...].
On the Purchase Date or the  Alternative  Purchase Date, as the case may be, for
any Equipment,  Lessee shall pay to Lessor the purchase price, together with all
sales and other taxes  applicable to the transfer of the Equipment and any other
amount payable and arising hereunder,  in immediately available funds, whereupon
Lessor  shall  transfer  to Lessee,  without  recourse  or warranty of any kind,
express or implied,  all of Lessor's  right,  title and  interest in and to such
Equipment  on an "As Is, Where Is" basis and file UCC-3  termination  statements
upon reasonable request by Lessee.

                  OWNERSHIP;  INSPECTION;  MARKING; FINANCING STATEMENTS. Lessee
shall affix to the  Equipment,  other than the Tenant  Improvements,  any labels
supplied by Lessor indicating ownership of such Equipment.  The Equipment is and
shall be the sole  property  of Lessor.  Lessee  shall  have no right,  title or
interest   therein,   except  as  lessee  under  a  Lease.   Other  than  Tenant
Improvements,  the  Equipment  is and shall at all times be and remain  personal
property  and shall not become a fixture.  Lessee  shall  obtain and record such
instruments  and take such steps as may be  necessary to prevent any person from
acquiring any rights in the Equipment, other than in the Tenant Improvements, by
reason of the  Equipment  being  claimed  or deemed  to be real  property.  Upon
request by 

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<PAGE>

Lessor,  Lessee shall obtain and deliver to Lessor valid and effective  waivers,
in recordable form, by the owners, landlords and mortgagees of the real property
upon which the  Equipment  is located or  certificates  of Lessee that it is the
owner of such real  property or that such real  property  is neither  leased nor
mortgaged. Lessee shall make the Equipment and its maintenance records available
for inspection by Lessor at reasonable times and upon reasonable notice.  Lessee
shall execute and deliver to Lessor for filing any UCC  financing  statements or
similar documents Lessor may reasonably request.

                  EQUIPMENT  USE.  Lessee  agrees  that  the  Equipment  will be
operated by competent,  qualified personnel in connection with Lessee's business
for the purpose for which the  Equipment  was  designed and in  accordance  with
applicable operating  instructions,  laws and government  regulations,  and that
Lessee  shall use all  reasonable  precautions  to prevent loss or damage to the
Equipment  from fire and other  hazards.  Lessee  shall  procure and maintain in
effect all orders,  licenses,  certificates,  permits,  approvals  and  consents
required by federal,  state or local laws or by any governmental body, agency or
authority in connection  with the delivery,  installation,  use and operation of
the Equipment.

                  MAINTENANCE.  Lessee, at its sole cost and expense, shall keep
the  Equipment in a suitable  environment  as  specified  by the  manufacturer's
guidelines or the  equivalent  and meet all  recertification  requirements,  and
shall  maintain  the  Equipment  in its original  condition  and working  order,
ordinary wear and tear  excepted.  At the reasonable  request of Lessor,  Lessee
shall furnish all proof of maintenance.

                  ALTERATION;  MODIFICATIONS;  PARTS. Lessee may alter or modify
the Equipment  only with the prior  written  consent of Lessor.  Any  alteration
shall be removed and the Equipment restored to its normal,  unaltered  condition
at Lessee's  expense  (without  damaging  the  Equipment's  originally  intended
function  or its value)  prior to its return to Lessor.  Any part  installed  in
connection  with warranty or  maintenance  service or which cannot be removed in
accordance with the preceding sentence shall be the property of Lessor.

                  RETURN OF EQUIPMENT.  Except for Equipment that has suffered a
Casualty  Loss (as  defined in  Paragraph  15 below) and is not  required  to be
repaired  pursuant  to  Paragraph  15 below or  Equipment  purchased  by  Lessee
pursuant to Paragraph 9 above,  upon  expiration of the Renewal Term of a Lease,
or upon demand by Lessor  pursuant to Paragraph 22 below,  Lessee shall  contact
Lessor for shipping  instructions and, at

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*Confidental Treatment Requested

<PAGE>

Lessee's own risk,  immediately  return the  Equipment,  freight  prepaid,  to a
location in the continental  United States  specified by Lessor.  At the time of
such return to Lessor, the Equipment shall (i) be in the operating order, repair
and  condition as required by or specified  in the original  specifications  and
warranties  of each  manufacturer  and vendor  thereof,  ordinary  wear and tear
excepted, and meet all recertification requirements and (ii) be capable of being
promptly assembled and operated by a third party purchaser or third party lessee
without  further  repair,  replacement,  alterations  or  improvements,  and  in
accordance and compliance with any and all statutes, laws, ordinances, rules and
regulations of any governmental  authority or any political  subdivision thereof
applicable  to the use and  operation  of the  Equipment.  Except  as  otherwise
provided under Paragraph 9 hereof, at least thirty days before the expiration of
the Renewal  Term,  Lessee shall give Lessor  notice of its intent to return the
Equipment at the end of such Renewal Term. During the thirty-day period prior to
the end of the Renewal Term,  Lessor and its  prospective  purchasers or lessees
shall have,  upon not less than two  business  days' prior  notice to Lessee and
during normal  business  hours, or at any time and without prior notice upon the
occurrence and  continuance  of an Event of Default,  the right of access to the
premises on which the Equipment is located to inspect the Equipment,  and Lessee
shall  cooperate  in  all  other  respects  with  Lessor's  remarketing  of  the
Equipment.  The provisions of this Paragraph 14 are of the essence of the Lease,
and upon application to any court of equity having jurisdiction in the premises,
Lessor  shall  be  entitled  to  a  decree  against  Lessee  requiring  specific
performance of the covenants of Lessee set forth in this Paragraph 14. If Lessee
fails to return the Equipment  when  required,  the terms and  conditions of the
Lease shall  continue to be  applicable  and Lessee  shall  continue to pay Rent
until the Equipment is received by Lessor.

                  CASUALTY INSURANCE;  LOSS OR DAMAGE.  Lessee will maintain, at
its own  expense,  liability  and  property  damage  insurance  relating  to the
Equipment, insuring against such risks as are customarily insured against on the
type of equipment  leased  hereunder by businesses in which Lessee is engaged in
such amounts, in such form, and with insurers satisfactory to Lessor;  provided,
however,  that the amount of insurance  against damage or loss shall not be less
than the greater of (a) the [...***...] of the Equipment and (b) the [...***...]
of  the  Equipment  specified  in  the  applicable  Schedule  [...***...].  Each
liability   insurance   policy  shall

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*Confidental Treatment Requested


<PAGE>

provide coverage  (including,  without limitation,  personal injury coverage) of
not less than  [...***...]  for each  occurrence,  and shall  name  Lessor as an
additional  insured;  and each property  damage policy shall name Lessor as sole
loss payee and all policies shall contain a clause requiring the insurer to give
Lessor at least thirty days prior written  notice of any alteration in the terms
or cancellation of the policy.  Lessee shall furnish an insurance certificate or
other evidence satisfactory to Lessor that the required insurance coverage is in
effect; provided,  however, Lessor shall have no duty to ascertain the existence
of or to examine the insurance  certificates or policies to advise Lessee if the
insurance  coverage does not comply with the requirements of this Paragraph.  If
Lessee fails to insure the  Equipment  as required,  Lessor shall have the right
but not the obligation to obtain such  insurance,  and the cost of the insurance
shall be for the  account  of Lessee  due as part of the next due  Rent.  Lessee
consents to Lessor's release,  upon its failure to obtain appropriate  insurance
coverage,  of any and all information necessary to obtain insurance with respect
to the Equipment or Lessor's interest therein.

         Until the  Equipment  is returned to and received by Lessor as provided
in Paragraph 14 above, Lessee shall bear the entire risk of theft or destruction
of, or damage to, the Equipment including, without limitation, any condemnation,
seizure or requisition of title or use ("Casualty Loss"). No Casualty Loss shall
relieve Lessee from its obligations to pay Rent except as provided in clause (b)
below.  When any Casualty Loss occurs,  Lessee shall  immediately  notify Lessor
and, at the option of Lessor,  shall  promptly (a) place such  Equipment in good
repair and working order;  or (b) pay Lessor an amount equal to the  [...***...]
of such  Equipment  and all other  amounts  (excluding  Rent)  payable by Lessee
hereunder, together with a late charge on such amounts at a rate per annum equal
to the [...***...]  hereunder (as reasonably determined by Lessor) from the date
of the  Casualty  Loss  through the date of payment of such  amounts,  whereupon
Lessor  shall  transfer to Lessee,  without  recourse  or  warranty  (express or
implied),  all of Lessor's interest,  if any, in and to such Equipment on an "AS
IS, WHERE IS" basis.  The proceeds of any insurance  payable with respect to the
Equipment  shall be applied,  at the option of Lessee if no Event of Default has
occurred  and is  continuing  (and  otherwise  at the option of Lessor),  either
towards  (i)  repair  of the  Equipment  or  (ii)  payment  of  any of  Lessee's
obligations    hereunder.    Lessee   hereby   appoints   Lessor   as   Lessee's
attorney-in-fact  to make claim

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<PAGE>

for, receive payment of, and execute and endorse all documents, checks or drafts
issued with respect to any Casualty Loss under any insurance  policy relating to
the Equipment.

                  TAXES.  Lessee  shall pay when  due,  and  indemnify  and hold
Lessor harmless from, all sales, use, excise and other taxes,  charges, and fees
(including,  without  limitation,  income,  franchise,  business and occupation,
gross receipts, licensing,  registration,  titling, personal property, stamp and
interest equalization taxes, levies, imposts, duties, charges or withholdings of
any  nature),  and if  resulting  from an act or omission of Lessee,  any fines,
penalties  or  interest  thereon,  imposed or levied by any  governmental  body,
agency or tax authority upon or in connection with the Equipment,  its purchase,
ownership,  delivery, leasing, possession, use or relocation of the Equipment or
otherwise in connection with the transactions  contemplated by each Lease or the
Rent  thereunder,  excluding  taxes on or  measured by the net income of Lessor.
Upon  request,  Lessee will  provide  proof of  payment.  Unless  Lessor  elects
otherwise,  Lessor will pay all property taxes on the Equipment for which Lessee
shall reimburse Lessor promptly upon request and proof of payment.  Lessee shall
timely  prepare and file all reports and returns  which are  required to be made
with respect to any  obligation of Lessee under this Paragraph 16. Lessee shall,
to the extent permitted by law, cause all billings of such fees, taxes,  levies,
imposts,  duties,  withholdings and governmental charges to be made to Lessor in
care of Lessee. Upon request, Lessee will provide Lessor with copies of all such
billings.  Lessee shall have the option to contest taxes  diligently and in good
faith as long as Lessee maintains  adequate  reserves for such taxes measured in
accordance with General Accepted Accounting Principles.

                  LESSOR'S  PAYMENT.  If Lessee fails to perform its obligations
under  Paragraph 15 or 16 above,  or  Paragraph 23 below,  Lessor shall have the
right  to  substitute  performance,  in which  case,  Lessee  shall  immediately
reimburse Lessor therefor.

                  GENERAL  INDEMNITY.  Each  Lease  is a net  lease.  Therefore,
Lessee shall indemnify Lessor and its successors and assigns  against,  and hold
Lessor  and its  successors  and  assigns  harmless  from,  any and all  claims,
actions,  damages,   obligations,   liabilities  and  all  costs  and  expenses,
including, without limitation,  reasonable legal fees, incurred by

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Lessor or its  successors  and  assigns  arising  out of each  Lease  including,
without  limitation,  the  purchase,  ownership,  delivery,  lease,  possession,
maintenance,  condition, use or return of the Equipment, or arising by operation
of law, except that Lessee shall not be liable for any claims, actions, damages,
obligations and costs and expenses  determined by a non-appealable,  final order
of a court of  competent  jurisdiction  have  occurred  as a result of the gross
negligence or willful misconduct of Lessor or its successors and assigns. Lessee
agrees that upon written notice by Lessor of the assertion of any claim, action,
damage,  obligation,  liability or lien, Lessee shall assume full responsibility
for the defense  thereof,  provided  that  Lessor's  failure to give such notice
shall not limit or otherwise  affect its rights  hereunder  except to the extent
Lessee incurs a loss as a direct result of such failure. Any payment pursuant to
this Paragraph (except for any payment of Rent) shall be of such amount as shall
be necessary so that,  after payment of any taxes required to be paid thereon by
Lessor,  including taxes on or measured by the net income of Lessor, the balance
will equal the amount due  hereunder.  The  provisions  of this  Paragraph  with
regard to  matters  arising  during a Lease  shall  survive  the  expiration  or
termination of such Lease.

                  ASSIGNMENT  BY LESSEE.  Lessee  shall not,  without  the prior
written consent of Lessor, (a) assign, transfer,  pledge or otherwise dispose of
any Lease or  Equipment,  or any  interest  therein;  (b)  sublease  or lend any
Equipment or permit it to be used by anyone other than Lessee and its  employees
agents, representatives, contractors and other authorized persons, provided that
Lessee shall  indemnify and hold Lessor and its successors and assigns  harmless
from any liability  arising  under,  or in  connection  with such persons use or
operation  of the  Equipment;  or (c)  move  any  Equipment  from  the  location
specified  for it in the  applicable  Schedule,  except  that  Lessee  may  move
Equipment to another  location within the United States provided that Lessee has
delivered  to Lessor (A) prior  written  notice  thereof  and (B) duly  executed
financing  statements  and other  agreements  and  instruments  (all in form and
substance  satisfactory  to Lessor)  necessary or, in the opinion of the Lessor,
desirable  to  protect  Lessor's  interest  in such  Equipment.  Notwithstanding
anything to the contrary in the immediately preceding sentence,  Lessee may keep
any Equipment  consisting of motor  vehicles or rolling stock at any location in
the United States.

                  ASSIGNMENT BY LESSOR.  Lessor may assign its interest or grant
a security interest in any Lease and the Equipment  individually or together, in
whole or in part. If Lessee is given written notice of any such  assignment,  it
shall immediately make all payments of Rent and other


<PAGE>

amounts hereunder  directly to such assignee.  Each such assignee shall have all
of the rights of Lessor under each Lease assigned to it. Lessee shall not assert
against any such assignee any set-off,  defense or counterclaim  that Lessee may
have against  Lessor or any other  person.  Notwithstanding  any  assignment  by
Lessor,  Lessor shall not be relieved of its obligations under any Lease, but in
no event shall Lessor be liable for any act or omission of its assignee.

                  DEFAULT;  NO WAIVER.  Lessee or any guarantor of any or all of
the obligations of Lessee hereunder  (together with Lessee, the "Lease Parties")
shall be in default under each Lease upon the occurrence of any of the following
events (each, an "Event of Default"): (a) Lessee fails to pay within ten days of
when due any amount  required to be paid by Lessee under or in  connection  with
any Lease; (b) any of the Lease Parties fails to perform in any material respect
any other  provision  under or in  connection  with a Lease or  violates  in any
material  respect any of the covenants or agreements of such Lease Parties under
or in  connection  with a  Lease;  (c)  any  representation  made  or  financial
information  delivered  or  furnished  by any of the Lease  Parties  under or in
connection  with a Lease shall  prove to have been  inaccurate  in any  material
respect when made;  (d) any of the Lease  Parties  makes an  assignment  for the
benefit of  creditors,  whether  voluntary  or  involuntary,  or consents to the
appointment of a trustee or receiver, or if either shall be appointed for any of
the Lease Parties or for a substantial  part of its property without its consent
and, in the case of any such  involuntary  proceeding,  such proceeding  remains
undismissed or unstayed for forty-five days following the commencement  thereof;
(e) any petition or  proceeding  is filed by or against any of the Lease Parties
under any Federal or State  bankruptcy or insolvency code or similar law and, in
the case of any such  involuntary  petition  or  proceeding,  such  petition  or
proceeding  remains  undismissed or unstayed for  forty-five  days following the
filing or  commencement  thereof,  or any of the Lease  Parties takes any action
authorizing any such petition or proceeding;  (f) any of the Lease Parties fails
to pay when due any indebtedness for borrowed money or under  conditional  sales
or  installment  sales  contracts or similar  agreements,  leases or obligations
evidenced by bonds, debentures, notes or other similar agreements or instruments
to any creditor  (including  Lessor under any other agreement) after any and all
applicable  cure  periods  therefor  shall have  elapsed if the amount  involved
exceeds [...***...] in the aggregate; (g) any judgment shall be rendered against
any of the Lease  Parties  which shall remain unpaid or unstayed for a period of
sixty days; (h) any of the Lease Parties shall dissolve,  liquidate,  wind up or
cease its business, sell or otherwise dispose of all or substantially all of its
assets; (i) any of the Lease Parties shall amend or modify its name, unless


<PAGE>

such Lease  Party  delivers  to Lessor  thirty  days prior to any such  proposed
amendment or modification  written notice of such amendment or modification  and
within  ten  days  before  such  amendment  or  modification  delivers  executed
financing statements (in form and substance satisfactory to the Lessor) provided
that Lessee shall have 10 business  days after notice to cure any default  under
this paragraph (i); (j) any of the Lease Parties shall merge or consolidate with
any other entity or make any material change in its capital  structure,  in each
case without  Lessor's prior written  consent,  which shall not be  unreasonably
withheld;  (k) any of the Lease  Parties  shall suffer any loss or suspension of
any material  license,  permit or other right or asset which loss has a material
adverse effect on Lessees ability to perform hereunder, or fail generally to pay
its debts as they  mature,  or call a meeting for purposes of  compromising  its
debts;  or (l) any of the Lease Parties shall deny or disaffirm its  obligations
hereunder or under any of the documents delivered in connection herewith.

                  REMEDIES.  Upon the occurrence and continuation of an Event of
Default for ten days after notice for a payment  Event of Default and for thirty
days after notice for all other Events of Default,  Lessor shall have the right,
in its sole discretion,  to exercise any one or more of the following  remedies:
(a)  terminate  each Lease;  (b) declare any and all Rent and other amounts then
due and any and all Rent and other  amounts  to  become  due  under  each  Lease
(collectively,  the "Lease  Obligations")  immediately due and payable; (c) take
possession of any or all items of Equipment,  wherever located,  without demand,
notice,  court order or other process of law, and without liability for entry to
Lessee's premises, for damage to Lessee's property or otherwise; (d) demand that
Lessee  immediately  return any or all  Equipment to Lessor in  accordance  with
Paragraph 14 above,  and, for each day that Lessee shall fail to return any item
of  Equipment,  Lessor may demand an amount  equal to the Rent  payable for such
Equipment in accordance  with Paragraph 14 above;  (e) lease,  sell or otherwise
dispose of the Equipment in a commercially  reasonable  manner,  with or without
notice and on public or private bid; (f) recover the following  amounts from the
Lessee (as damages,  including  reimbursement of costs and expenses,  liquidated
for all  purposes  and not as a penalty):  (i) all costs and  expenses of Lessor
reimbursable  to  it  hereunder,  including,  without  limitation,  expenses  of
disposition  of the  Equipment,  reasonable  legal  fees and all  other  amounts
specified  in

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Paragraph  23 below;  (ii) an  amount  equal to the sum of (A) any  accrued  and
unpaid Rent through the later of (1) the date of the  applicable  default or (2)
the date that Lessor has obtained possession of the Equipment or such other date
as Lessee has made an effective  tender of possession of the Equipment to Lessor
(the "Default Date") and (B) if Lessor resells or re-lets the Equipment, Rent at
the periodic rate provided for in each Lease for the  additional  period that it
takes Lessor to resell or re-let all of the  Equipment;  (iii) the present value
of all future  Rent  reserved in the Leases and  contracted  to be paid over the
unexpired  Term of the Leases  discounted  at  [...***...]  simple  interest per
annum;  (iv) the present value of the reversionary  value of the Equipment as of
the  expiration  of the  Term  of the  applicable  Lease  as  set  forth  on the
applicable  Schedule  discounted at  [...***...]  simple  interest;  and (v) any
indebtedness for Lessee's indemnity under Paragraph 18 above, plus a late charge
at the rate specified in Paragraph 3 above,  less the amount received by Lessor,
if any, upon sale or re-let of the  Equipment;  and (g) exercise any other right
or remedy to  recover  damages  or  enforce  the terms of the  Leases.  Upon the
occurrence  and  continuance  of an Event of Default or an event  which with the
giving of notice or the passage of time,  or both,  would  result in an Event of
Default,  Lessor shall have the right, whether or not Lessor has made any demand
or the obligations of Lessee hereunder have matured, to appropriate and apply to
the payment of the  obligations  of Lessee  hereunder all security  deposits and
other deposits (general or special, time or demand, provisional or final) now or
hereafter held by and other  indebtedness  or property now or hereafter owing by
Lessor to Lessee.  Lessor may pursue any other  rights or remedies  available at
law or in equity,  including,  without  limitation,  rights or remedies  seeking
damages,  specific  performance and injunctive  relief. Any failure of Lessor to
require strict  performance by Lessee,  or any waiver by Lessor of any provision
hereunder or under any  Schedule,  shall not be construed as a consent or waiver
of any other  breach of the same or of any other  provision.  Any  amendment  or
waiver of any provision hereof or under any Schedule or consent to any departure
by Lessee 1herefrom or therefrom shall be in writing and signed by Lessor.

         No right or  remedy  is  exclusive  of any  other  provided  herein  or
permitted by law or equity. All such rights and remedies shall be cumulative and
may be enforced concurrently or individually from time to time.

- -------------------------
*Confidental Treatment Requested

<PAGE>

                  LESSOR'S  EXPENSE.  Lessee  shall pay Lessor on demand all its
reasonable  expenses  which  shall not exceed  [...***...]  without  the written
consent of Lessee  (including  reasonable  legal fees and expenses)  incurred in
connection  with the  preparation,  execution and delivery of this Agreement and
any  other  agreement  and  transaction  contemplated  hereby  and all costs and
expenses in protecting and enforcing Lessor's rights and interests in each Lease
and  the  Equipment,   including,  without  limitation,  legal,  collection  and
remarketing  fees and  expenses  incurred  by Lessor  in  enforcing  the  terms,
conditions or provisions of each Lease or, upon the occurrence and  continuation
of an Event of Default.

                  LESSEE'S  WAIVERS.  To the extent permitted by applicable law,
Lessee hereby waives any and all rights and remedies  conferred upon a lessee by
Sections 2A-508 through 2A-522 of the UCC; provided,  however, that Lessee shall
have the right to recover  damages  from  Lessor for any breach by Lessor of its
obligations  under this  Agreement.  To the extent  permitted by applicable law,
Lessee also hereby  waives any rights now or  hereafter  conferred by statute or
otherwise which may require Lessor to sell, lease or otherwise use any Equipment
in  mitigation  of Lessor's  damages as set forth in Paragraph 22 above or which
may otherwise limit or modify any of Lessor's rights or remedies under Paragraph
22,  except  that  Lessee  shall have the right to  require  Lessor to convey to
Lessee,  without  representation,  warranty or recourse,  all of Lessors rights,
title and interest in and to the Equipment  upon Lessors  receipt,  following an
event of default  and the  exercise  of the  Lessors  remedies,  of the  amounts
specified  in  Paragraph  22(f).  Any  action by Lessee  against  Lessor for any
default by Lessor under any Lease shall be  commenced  within one year after any
such cause of action accrues.

                  NOTICES; ADMINISTRATION.  Except as otherwise provided herein,
all  notices,  approvals,  consents,   correspondence  or  other  communications
required or desired to be given hereunder shall be given in writing and shall be
delivered by overnight  courier,  hand delivery or certified or registered mail,
postage prepaid, if to Lessor, then to Technology Finance Division, 76 Batterson
Park Road, Farmington,  Connecticut 06032, Attention:  Assistant Vice President,
Lease  Administration,  with a copy to Lessor at Riverway II, West Office Tower,
9399 West Higgins Road, Rosemont,  Illinois 60018, Attention:  Legal

- -------------------------
*Confidental Treatment Requested

<PAGE>

Department,  if to Lessee,  then to Sugen,  Inc., 351 Galveston  Drive,  Redwood
City,  California  94063-4720,  Attention:  Vice President Finance or such other
address as shall be designated by Lessee or Lessor to the other party.  All such
notices and correspondence shall be effective when received.

                  REPRESENTATIONS. Lessee represents and warrants to Lessor that
(a) Lessee is duly  organized,  validly  existing and in good standing under the
laws  of the  State  of its  incorporation;  (b)  the  execution,  delivery  and
performance by Lessee of this Agreement are within  Lessee's  powers,  have been
duly authorized by all necessary action,  and do not and will not contravene (i)
Lessee's  organizational  documents or (ii) any law or  contractual  restriction
binding on or affecting Lessee; (c) no authorization or approval or other action
by, and no notice to or filing with,  any  governmental  authority or regulatory
body is required for the due  execution,  delivery and  performance by Lessee of
this  Agreement;  (d) each  Lease  constitutes  the  legal,  valid  and  binding
obligations of Lessee  enforceable  against Lessee in accordance  with its terms
except as may be limited by bankruptcy, reorganization, receivership, insolvency
or other laws affecting the enforcement of creditors  rights  generally;  (e) to
the  knowledge of Lessee the cost of each item of Equipment  does not exceed the
fair and usual price for such type of equipment  purchased in like  quantity and
reflects all discounts,  rebates,  and allowances for the Equipment  (including,
without limitation,  discounts for advertising, prompt payment, testing or other
services) given to the Lessee by the manufacturer, supplier or any other person;
and (f) all information  supplied by Lessee to Lessor in connection  herewith is
correct and does not omit any  material  statement  necessary to insure that the
information supplied is not misleading.

                  FURTHER  ASSURANCES.  Lessee, upon the request of Lessor, will
execute, acknowledge, record or file, as the case may be, such further documents
and do such further acts as may be reasonably necessary,  desirable or proper to
carry  out more  effectively  the  purposes  of this  Agreement.  Lessee  hereby
appoints Lessor as its limited  attorney-in-fact  to execute on behalf of Lessee
and  authorizes  Lessor to file without  Lessee's  signature  any UCC  financing
statements and amendments Lessor deems advisable.

- -------------------------
*Confidental Treatment Requested

<PAGE>

                  FINANCIAL  STATEMENTS.  Lessee shall deliver to Lessor: (a) as
soon as available, but not later than 120 days after the end of each fiscal year
of Lessee and its consolidated  subsidiaries,  the  consolidated  balance sheet,
income statement and statements of cash flows and shareholders equity for Lessee
and its consolidated  subsidiaries  (the "Financial  Statements") for such year,
reported  on by  independent  certified  public  accountants  without an adverse
qualification;  and (b) as soon as  available,  but not later than 60 days after
the end of each of the first three fiscal  quarters in any fiscal year of Lessee
and its  consolidated  subsidiaries,  the Financial  Statements  for such fiscal
quarter,  as filed with the SEC.  Lessee shall also deliver to Lessor as soon as
available copies of all press releases and other similar  communications  issued
by Lessee and upon request of Lessor.

                  CONSENT TO  JURISDICTION.  Lessee  irrevocably  submits to the
jurisdiction  of any Illinois state or federal court sitting in Illinois for any
action  or  proceeding  arising  out of or  relating  to this  Agreement  or the
transactions  contemplated hereby, and Lessee irrevocably agrees that all claims
in respect of any such action or proceeding  may be heard and determined in such
Illinois state or federal court.

                  WAIVER OF JURY TRIAL.  LESSEE AND LESSOR IRREVOCABLY WAIVE ALL
RIGHT TO TRIAL BY JURY IN ANY ACTION,  PROCEEDING OR COUNTERCLAIM ARISING OUT OF
OR RELATING TO THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY.

                  FINANCE  LEASE.  Lessee and Lessor  agree that each Lease is a
"Finance Lease" as defined by Section 2A-103(g) of the UCC. Lessee  acknowledges
that Lessee has reviewed and approved each written  Supply  Contract (as defined
by UCC 2A-103(y))  covering Equipment purchased from each "Supplier" (as defined
by UCC 2A-103(x)) thereof.

                  NO AGENCY.  Lessee  acknowledges  and agrees that  neither the
manufacturer or supplier, nor any salesman, representative or other agent of the
manufacturer or supplier, is an agent of Lessor. No salesman,  representative or
agent of the  manufacturer  or supplier is authorized to waive or alter any term
or condition of this Agreement or any Schedule and no  representation  as to the
Equipment or any other matter by the  manufacturer  or supplier shall in any way
affect Lessee's duty to pay Rent and perform its other  obligations as set forth
in this Agreement or any Schedule.

                  SPECIAL TAX INDEMNIFICATION.  Lessee acknowledges that

<PAGE>

Lessor,  in  determining  the Rent due  hereunder,  has assumed that certain tax
benefits as are provided to an owner of property under the Internal Revenue Code
of 1986, as amended (the "Code"), and under applicable state tax law, including,
without  limitation,  depreciation  deductions under Section 168(b) of the Code,
and deductions  under Section 163 of the Code in an amount at least equal to the
amount of interest  paid or accrued by Lessor with  respect to any  indebtedness
incurred by Lessor in financing its purchase of the Equipment,  are available to
Lessor as a result of the lease of the Equipment.  In the event Lessor is unable
to obtain such tax benefits as a result of an act or omission of Lessee of which
Lessee has prior  written  notice and  opportunity  of comply,  is  required  to
include in income any amount  other than the Rent or is  required  to  recognize
income  in  respect  of the  Rent  earlier  than  anticipated  pursuant  to this
Agreement, Lessee shall pay Lessor additional rent ("Additional Rent") in a lump
sum in an amount  needed to provide  Lessor  with the same  after-tax  yield and
after-tax  cash flow as would have been  realized  by Lessor had Lessor (i) been
able to obtain such tax benefits, and (ii) not been required to recognize income
in respect of the Rent earlier than anticipated pursuant to this Agreement.  The
Additional Rent shall be computed by Lessor,  which computation shall be binding
on Lessee absent good faith contest by Lessee.  The Additional Rent shall be due
immediately  upon  written  notice by Lessor to Lessee of Lessor's  inability to
obtain tax  benefits,  the inclusion of any amount in income other than the Rent
or the  recognition  of income in respect of the Rent earlier  than  anticipated
pursuant to this  Agreement.  The  provisions of this Paragraph 33 shall survive
the termination of this Agreement.

                  GOVERNING LAW;  SEVERABILITY.  EACH LEASE SHALL BE GOVERNED BY
THE LAWS OF THE STATE OF ILLINOIS  WITHOUT  GIVING EFFECT TO THE CONFLICT OF LAW
PRINCIPLES   THEREOF.   IF  ANY  PROVISION  SHALL  BE  HELD  TO  BE  INVALID  OR
UNENFORCEABLE, THE VALIDITY AND ENFORCEABILITY OF THE REMAINING PROVISIONS SHALL
NOT IN ANY WAY BE AFFECTED OR IMPAIRED.

         LESSEE  ACKNOWLEDGES  THAT  LESSEE  HAS  READ  THIS  AGREEMENT  AND THE
SCHEDULES  HERETO,  UNDERSTANDS  THEM, AND AGREES TO BE BOUND BY THEIR TERMS AND
CONDITIONS.  FURTHER,  LESSEE  AND  LESSOR  AGREE  THAT THIS  AGREEMENT  AND THE
SCHEDULES  DELIVERED AND SIGNED BY LESSEE AND LESSOR IN CONNECTION HEREWITH FROM
TIME TO TIME AND THE  COMMITMENT  LETTER DATED MARCH 20, 1997, AS EXECUTED MARCH
25, 1997, ARE THE COMPLETE AND EXCLUSIVE  STATEMENT OF THE AGREEMENT BETWEEN THE
PARTIES, SUPERSEDING ALL PROPOSALS OR PRIOR AGREEMENTS, ORAL OR WRITTEN, AND ALL


<PAGE>

OTHER COMMUNICATIONS BETWE9EN THE PARTIES RELATING TO THE SUBJECT MATTER HEREOF.

         IN WITNESS  WHEREOF,  the parties  hereto have  executed or caused this
Agreement to be duly executed by their duly authorized  officers as of this ____
day of ______________, 1997.


SUGEN, INC.                           TRANSAMERICA BUSINESS CREDIT CORPORATION

By:                                   By:
   -----------------------------         -----------------------------
Name:                                 Name:
     ---------------------------           ---------------------------
Title:                                Title:
      --------------------------            --------------------------

Federal Identification
Number 13-3629196

<PAGE>


                        Schedule for Tenant Improvements

                       SCHEDULE TO MASTER LEASE AGREEMENT

                             Dated as of __________

                                 Schedule No. __

Lessor Name & Mailing Address                    Lessee Name & Mailing Address
Transamerica Business Credit Corporation                 Sugen, Inc.
Riverway II                                      351 Galveston Drive
West Office Tower                                Redwood City, California 
9399 West Higgins Road                           94063-4720
Rosemont, Illinois  60018

Equipment Location (if different than Lessee's address above):


This Schedule covers the following described equipment ("Equipment").

         See Exhibit II attached hereto and made a part hereof.

The  Equipment is hereby leased  pursuant to the  provisions of the Master Lease
Agreement between the undersigned  Lessee and Lessor dated as of __________ (the
"Master  Lease"),  the  terms of which  are  incorporated  herein  by  reference
thereto,  plus the following  additional  terms,  provisions and  modifications.
Lessor reserves the right to adjust the monthly  payments in accordance with the
Commitment  Letter dated  _____________,  between the Lessor and Lessee,  if the
Lessor  has not  received  this  Schedule  executed  by the Lessee  within  ____
business days from the date set forth above.

         1.  Term (Number of Months)
         2.  Equipment Cost
         3.  Commencement Date
         4.  a.      Rate Factor (months)
             a.      Rate Factor (month)
         5.  Total Rents
         6.  Advance Rents (months)
         7.  Monthly rental payments for months ____


<PAGE>

             (including  monthly  sales/use  tax)  will  be  in  the  amount  of
             $________  and  the  second  such  rental  payment  will  be due on
             ______________ and subsequent rental payments will be due on ______
             each  month  thereafter.   Monthly  rental  payment  for  month  __
             (including sales/use tax) will be in the amount of $__________

         1.  Security Deposit

         2.  In addition  to the monthly rental  payments  provided  for herein,
             Lessee  shall  pay to  Lessor,  as  interim  rent,  payable  on the
             commencement date specified above, an amount equal to 1/30th of the
             monthly rental payment (including monthly sales/use tax) multiplied
             by the  number of days from and  including  the  commencement  date
             through the end of the same calendar month.

Renewal Terms:

Lessee shall give Lessor ____ days prior written notice if it does not intend to
make the __ Monthly Rent described in __. In the event Lessee fails to give such
notice and Lessee does not make the ____ payment and provided  that the Lessee's
Real Estate  Lease Term  exceeds the Tenant  Improvement  Term,  the lease shall
automatically  renew for a term of _____ months with Monthly Rental equal to __%
of Equipment Cost payable  monthly in advance.  At the expiration of the renewal
period, Lessee may purchase all (but not less than all) the Equipment for $____,
plus sales and other taxes.

Tenant Improvements Termination Provisions:

If Lessee elects to vacate its present operating facilities (which is defined as
any facility in which Lessor's  Tenant  Improvements  reside),  then Lessor will
release its ownership in all its Tenant  Improvements that cannot be removed and
used and Lessee shall pay a higher  monthly  rental factor on the remaining term
of such Tenant  Improvements by ___% (or from ___% of Tenant  Improvements  Cost
monthly to ___% of Tenant Improvements Cost).

<PAGE>

Except as expressly provided or modified hereby, all the terms and provisions of
the Master Lease Agreement shall remain in full force and effect.

In the event this Lease is not  renewed  pursuant  to the terms  hereof,  Lessee
shall make the __th Monthly  Rental  Payment on the Purchase Date of __________.
On the  Purchase  Date,  Lessee  shall  purchase all (but not less than all) the
Equipment for $_____, plus applicable sales and other taxes.

The Stipulated  Loss Value of any items of Equipment shall be an amount equal to
the present value of all future Rent  discounted at a rate of __% per annum plus
the Reversionary Value.

The Reversionary Value of any item of Equipment shall be $____.

In witness whereof, this Schedule is hereby executed and agreed to this ____ day
of ________________, 1997.


TRANSAMERICA BUSINESS CREDIT                SUGEN, INC.
CORPORATION                                 (Lessee)
(Lessor)

By:                                         By:
   ------------------------------              -------------------------------
Title:                                      Title:
      ---------------------------                  ---------------------------

<PAGE>



       Schedule for Laboratory, Computer and Office Equipment and Software

                       SCHEDULE TO MASTER LEASE AGREEMENT

                             Dated as of __________

                                 Schedule No. __

Lessor Name & Mailing Address                   Lessee Name & Mailing Address
Transamerica Business Credit Corporation               Sugen, Inc.
Riverway II                                     351 Galveston Drive
West Office Tower                               Redwood City, California
9399 West Higgins Road                          94063-4720
Rosemont, Illinois  60018

Equipment Location (if different than Lessee's address above):


This Schedule covers the following described equipment ("Equipment").

         See Exhibit II and Rider I attached hereto and made a part hereof.

The  Equipment is hereby leased  pursuant to the  provisions of the Master Lease
Agreement between the undersigned  Lessee and Lessor dated as of __________ (the
"Master  Lease"),  the  terms of which  are  incorporated  herein  by  reference
thereto,  plus the following  additional  terms,  provisions and  modifications.
Lessor reserves the right to adjust the monthly  payments in accordance with the
Commitment  Letter dated  _____________,  between the Lessor and Lessee,  if the
Lessor  has not  received  this  Schedule  executed  by the Lessee  within  ____
business days from the date set forth above.

         I.   Term (Number of Months)
         II.  Equipment Cost
         III. Commencement Date
         IV.  a.      Rate Factor (months __ through __)
              a)      Rate Factor (month __)
         V.   Total Rents
         VI.  Advance Rents (months __ and __)

<PAGE>

         VII. Monthly  rental  payments  for  months __  through  __  (including
              monthly  sales/use tax) will be in the amount of $________ and the
              second such rental  payment will be due on and  subsequent  rental
              payments  will be due on the  same day of each  month  thereafter.
              Monthly rental payment for month __ (including sales/use tax) will
              be in the amount of $__________

         I.   Security Deposit

         II.  In addition to the monthly rental  payments  provided  for herein,
              Lessee  shall pay to  Lessor,  as  interim  rent,  payable  on the
              commencement  date specified  above,  an amount equal to 1/30th of
              the monthly  rental  payment  (including  monthly  sales/use  tax)
              multiplied   by  the  number  of  days  from  and   including  the
              commencement  date  through  the end of the same  calendar  month;
              provided,   however,   no  interim   rent  shall  be  due  if  the
              Commencement  Date is on or after the last three (3) business days
              of a month.

Renewal Terms:

Lessee shall give Lessor ____ days prior written notice if it does not intend to
make the __ monthly rental payment described in __. In the event Lessee fails to
give such notice and Lessee  does not make the __ monthly  rental  payment,  the
lease shall  automatically  renew for a term of _____ months with _____  monthly
rental  payments equal to __% of Equipment Cost payable  monthly in advance plus
an  additional  payment  equal  to __% of  Equipment  Cost due at the end of the
Renewal Term,  plus  applicable  sales and other taxes. At the expiration of the
Renewal Term,  Lessee may purchase all (but not less than all) the Equipment for
$____, plus sales and other taxes.

Except as expressly provided or modified hereby, all the terms and provisions of
the Master Lease Agreement shall remain in full force and effect.

In the event this Lease is not  renewed  pursuant  to the terms  hereof,  Lessee
shall make the __ Monthly Rental Payment on the Purchase Date of 


<PAGE>

__________.  On the Purchase Date,  Lessee shall purchase all (but not less than
all) the Equipment for $_____, plus applicable sales and other taxes.

The Stipulated  Loss Value of any items of Equipment shall be an amount equal to
the present value of all future Rent  discounted at a rate of __% per annum plus
the Reversionary Value.

The Reversionary Value of any item of Equipment shall be $____.

In witness whereof, this Schedule is hereby executed and agreed to this ____ day
of ________________, 1997.


TRANSAMERICA BUSINESS CREDIT                SUGEN, INC.
CORPORATION                                 (Lessee)
(Lessor)

By:                                         By:
   ------------------------------              -------------------------------
Title:                                      Title:
      ---------------------------                  ---------------------------




                                         ***TEXT OMITTED AND FILED SEPARATELY
                                            CONFIDENTIAL TREATMENT REQUESTED
                                            UNDER 17 C.F.R. SS. 200.80(B)(4),
                                            200.83 AND 240.24B-2

GERALD A. MICHAUD
Senior Vice President

Transamerica Business
Credit Corporation
Technology Finance Division
76 Batterson Park Road
Farmington, CT  06032-2571
Telephone 860 677-6466
Fax 860 677-6766

March 20, 1997


Ms. Christine Gray-Smith
Vice President Finance
Sugen, Inc.
515 Galveston Drive
Redwood City, CA  94063-4720

Dear Christine:

Transamerica   Business  Credit   Corporation  -  Technology   Finance  Division
("Lessor") is pleased to offer to lease the Equipment  described below to Sugen,
Inc. ("Lessee"). This Commitment supersedes all prior correspondence, proposals,
and oral or other communications relating to leasing arrangements between Lessee
and Lessor. The outline of this offer is as follows:

Lessee:                    Sugen, Inc.

Lessor:                    Transamerica Business Credit Corporation - Technology
                           Finance  Division and/or its  affiliates,  successors
                           and assigns.

Guarantors:                    None.

Equipment:                 1.  Laboratory,  Computer  and Office  Equipment  and
                               software  as will  be  further  described  in the
                               lease  documentation.  All  equipment  subject to
                               approval  of  Lessor  prior  to  funding, 

<PAGE>


                               which approval will not be unreasonably withheld.

                            A. Tenant  Improvements as will be further described
                               in the lease documentation.


                            B. The  Equipment  and  Tenant   Improvements  shall
                               include   sale-leaseback  items  purchased  after
                               December 1, 1996.

Equipment Cost:                Not to  exceed  $3,500,000  (Tenant  Improvements
                               limited to  [...***...]  and Software  limited to
                               [...***...].

Equipment Location:            Redwood  City,   California  or  other  locations
                               acceptable to Lessor,  which acceptance shall not
                               be unreasonably withheld.

Anticipated Delivery:          December 1, 1996 through June 30, 1998.

Termination of
Commitment:                    This  commitment  will  terminate  if  the  first
                               delivery of Equipment is not completed and funded
                               on or before May 31, 1997.  The final delivery of
                               Equipment shall not be later than June 30, 1998.

Lease Term Commencement:       Upon  delivery  acceptance  and  funding  of  the
                               Equipment or upon each  completion  of deliveries
                               of items of Equipment  with aggregate cost of not
                               less than [...***...],  but in no event shall any
                               Equipment be delivered later than June 30, 1998.

Term:
(Equipment and Software)       From each Lease Term Commencement until 49 months
                               from the first day of the month next following or
                               on the same date as the Lease  Term  Commencement
                               if that date is the first date of the month.

Term:
(Tenant Improvements)          From each Lease Term Commencement until 37 months
                               from the first day of the month next following or
                               on the same date as the Lease  Term  Commencement
                               if that date is the first date of the month.

Lease Repayment Terms:


<PAGE>

(Equipment and Software)       Monthly  Rent for  months 1  through  48 equal to
                               [...***...] of Equipment Cost payable  monthly in
                               advance,  plus applicable  sales and other taxes.
                               Monthly Rent for month 49 equal to [...***...] of
                               Equipment  Cost.  The first and 48th months' rent
                               shall be  payable  in  advance.  Lessee may elect
                               Automatic  Renewal provision of the lease in lieu
                               of  making  the  49th  monthly  rent  payment  as
                               described above upon giving 60 days prior written
                               notice to  Lessor.  As of the date of each  Lease
                               Term  Commencement,  the  Monthly  Rent  Payments
                               shall be fixed for the term.

Lease Repayment Terms:
(Tenant Improvements)          Monthly  Rent for  months 1  through  36 equal to
                               [...***...]  of  Tenant   Improvements  Cost  and
                               Equipment Cost payable  monthly in advance,  plus
                               applicable  sales and other  taxes.  Monthly Rent
                               for month 37 equal to  [...***...]  of  Equipment
                               Cost.  The first and 36th  months'  rent shall be
                               payable in  advance.  Lessee may elect  Automatic
                               Renewal  provision of the lease in lieu of making
                               the 37th month's rent payment as described  above
                               upon  giving  60 days  prior  written  notice  to
                               Lessor.  As  of  the  date  of  each  Lease  Term
                               Commencement,  the Monthly Rent Payments shall be
                               fixed for the term.

                               The Lessor  reserves  the right to  increase  the
                               Monthly  Rent  Payments  as of the  date  of each
                               Lease  Term  Commencement   commensurate  to  the
                               [...***...]  of the interest rates of [...***...]
                               (in the case of Equipment)  and  [...***...]  (in
                               the case of Tenant  Improvements  Cost)  from the
                               week  ending  March  5,  1997   ([...***...]  and
                               [...***...],  respectively) to the week preceding
                               the  date of each  Lease  Term  Commencement,  as
                               published in the Wall Street Journal.

- -------------------------
*Confidental Treatment Requested

<PAGE>

Interim Rent  Payments:        In the event that the Lease Term  Commencement is
                               not on the first day of the month,  Interim  Rent
                               Payments   shall  accrue  from  each  Lease  Term
                               Commencement  until the next following  first day
                               of a month  and  shall be  payable  at the end of
                               that  month.   Interim  Rent  Payments  shall  be
                               calculated   at  the  daily   equivalent  of  the
                               currently  adjusted Monthly Payment.  Lessee will
                               not be charged  Interim Rent on any Schedule that
                               has a  Commencement  Date that starts on or after
                               the last 3 business days of a month.

Purchase Option:
(Equipment and Software)       Lessee shall have the option to purchase all (but
                               not less than all) the  Equipment or any schedule
                               at the  expiration  of the term of the  Lease for
                               [...***...],  plus  applicable  sales  and  other
                               taxes.

Automatic Renewal:
(Equipment and Software)       In the  event  Lessee  does not elect to make the
                               49th  monthly  rent  as  described  in the  Lease
                               Repayment   Terms   above,    the   lease   shall
                               automatically  renew for a term of twelve months.
                               The Monthly Rental will equal  [...***...] of the
                               original   Equipment  Cost  payable   monthly  in
                               advance plus [...***...]  equal to [...***...] of
                               the Equipment  Cost,  after which time the Lessee
                               may purchase the Equipment for  [...***...]  plus
                               sales and other  applicable  taxes due at the end
                               of the Renewal Term.

Purchase Option or
Automatic Renewal:
(Tenant Improvements)          Lessee shall have the option to purchase all (but
                               not less than all) of the Tenant  Improvements at
                               the end of the lease  term for  [...***...]  plus
                               applicable  sales and other taxes.  If the Lessee
                               renews  its  existing  Real  Estate  Lease  for a
                               period that exceeds the Tenant Improvements Lease
                               Term,  then  Lessee may  automatically  renew the
                               lease in 

- -------------------------
*Confidental Treatment Requested

<PAGE>

                               lieu of making the 37th  monthly  rent payment as
                               described in the Lease Repayment Terms above, the
                               lease  shall  automatically  renew  for a term of
                               twelve  months  with  Monthly   Rental  equal  to
                               [...***...]  of the original  Tenant  Improvement
                               costs  payable  monthly in  advance,  after which
                               time the  Lessee  may  purchase  all but not less
                               than   all  of  the   Tenant   Improvements   for
                               [...***...] plus sales and other applicable taxes
                               due at the end of the Renewal Term.

Documentation:                 The  documentation  relating to this  transaction
                               shall implement the  transaction  contemplated by
                               this  commitment  letter to the  satisfaction  of
                               Lessor and its counsel, shall be fully acceptable
                               to Lessor and Lessee and their counsel, and shall
                               contain  conditions  precedent,  representations,
                               warranties  and  covenants  by  Lessee  and shall
                               provide for events of defaults and remedies,  all
                               as reasonably required by Lessor for transactions
                               of this type.  The  documentation  shall include,
                               but not be limited  to, the terms and  conditions
                               described in this commitment letter.

Insurance:                     Prior to any  delivery of  Equipment,  the Lessee
                               shall   furnish  a   certificate   of   insurance
                               acceptable  to the  Lessor in amount,  type,  and
                               term  covering the Equipment  including  primary,
                               all risk,  physical  damage,  property damage and
                               bodily  injury  with  appropriate  loss payee and
                               additional  insured  endorsements in favor of the
                               Lessor.

Taxes:                         Sales  or  use  taxes   would  be  added  to  the
                               Equipment Cost or collected on the gross rentals,
                               as appropriate.

Representations and
Additional Covenants:          There shall be no actual or  threatened  conflict
                               with, or violation of, any regulatory statute,

- -------------------------
*Confidental Treatment Requested

<PAGE>

                               standard  or rule  relating  to the  Lessee,  its
                               present or future operations, or the Collateral.

                               All  information  supplied by the Lessee shall be
                               materially   correct   and  shall  not  omit  any
                               statement   necessary  to  make  the  information
                               supplied  not be  misleading.  There  shall be no
                               material  breach  of  the   representations   and
                               warranties  of  the  Lessee  in  the  Lease.  The
                               representations  shall include that the Equipment
                               Cost  of  each  item of the  Equipment  does  not
                               exceed the fair and usual  price for such type of
                               Equipment  purchase in like quantity purchased of
                               such item and reflects all discounts, rebates and
                               allowances  for the Equipment  given to Lessee by
                               the  manufacturer,  supplier or any other  person
                               including,  without  limitation,   discounts  for
                               advertising,  prompt  payment,  testing  or other
                               services.

Conditions Precedent to
Each Lease Term
Commencement:                  1. No material  adverse  change in the  financial
                                  condition,   operation  or  prospects  of  the
                                  Lessee prior to funding.  The Lessor  reserves
                                  its right to rescind any unused portion of its
                                  commitment in the event of a material  adverse
                                  change in the  financial or business  standing
                                  of the Lessee.

                               1. Completion  of  the  documentation  and  final
                                  terms of the proposed  financing  satisfactory
                                  to Lessor and Lessor's counsel, and Lessee and
                                  Lessee's counsel.

                               2. Results of all due diligence,  including lien,
                                  judgment and tax  searches  and other  matters
                                  Lessor may request  shall be  satisfactory  to
                                  Lessor and Lessor's counsel.

                               3. Receipt  by  Lessor  of  duly  executed  Lease
                                  documentation    in   form    and    substance
                                  satisfactory to Lessor and its counsel.

- -------------------------
*Confidental Treatment Requested

<PAGE>

                               4. Lessor  shall  receive  title  and a valid and
                                  perfected  first  priority  lien and  security
                                  interest  in  the   Equipment  and  all  other
                                  Equipment  acquired  through  the  use of this
                                  Commitment,  and Lessor  shall  have  received
                                  satisfactory  evidence that there are no liens
                                  on any Equipment except as expressly permitted
                                  herein.

Tenant Improvements
Termination Provision:         If  the  Lessee  elects  to  vacate  its  present
                               operating  facility  (which  is  defined  as  any
                               facility in which  Lessor's  Tenant  Improvements
                               reside),   then  the  Lessor  will   release  its
                               ownership   position   in  all   of  its   Tenant
                               Improvements.  In return, the Lessee will provide
                               compensation  to the  Lessor  for the  release of
                               Tenant Improvements in the form of an increase to
                               the monthly rental factor on the remaining rental
                               of Tenant  Improvements  which  cannot be removed
                               and used by [...***...]  (or from  [...***...] to
                               [...***...] of Tenant Improvements Cost monthly).
                               The release  will be subject to the Lessee  being
                               in  substantial  compliance  with all other terms
                               and conditions of the lease.

Fees and Expenses:             The Lessee shall be responsible  for the Lessor's
                               reasonable  expenses  not to  exceed  [...***...]
                               without Lessee's written consent (including legal
                               expenses) in connection with the transaction.

Law:                           This letter and the  proposed  Lease are intended
                               to be governed  by and  construed  in  accordance
                               with Illinois law without  regard to its conflict
                               of law provisions.

Indemnity:                     Lessee  agrees to indemnify  and to hold harmless
                               Lessor, and its officers, directors and employees
                               against  all  claims,  damages,  liabilities  and
                               expenses  which may be  incurred  by or  asserted

- -------------------------
*Confidental Treatment Requested

<PAGE>

                               against  any such  person in  connection  without
                               arising out of this  letter and the  transactions
                               contemplated hereby, other than claims,  damages,
                               liability,   and  expense   resulting  from  such
                               person's gross negligence or willful misconduct.

Confidentiality:               This  letter  is   delivered   to  you  with  the
                               understanding  that neither it nor its  substance
                               shall be  disclosed  publicly or privately to any
                               third   person   except   those   who  are  in  a
                               confidential  relationship  to you  (such as your
                               legal counsel and accountants), or where the same
                               is  required  by law and then  only on the  basis
                               that   it  not  be   further   disclosed,   which
                               conditions  the Lessee and its agents agree to be
                               bound by upon acceptance of this letter.

                               Without limiting the generality of the foregoing,
                               none of such persons shall use or refer to Lessor
                               or to any affiliate name in any disclosures  made
                               in  connection  with  any  of  the   transactions
                               without Lessor's prior written consent.

Conditions of
Acceptance:                    This  Commitment  Letter  is  intended  to  be  a
                               summary  of the most  important  elements  of the
                               agreement  to enter  into a  leasing  transaction
                               with   Lessee,   and   it  is   subject   to  all
                               requirements  and  conditions  contained in Lease
                               documentation  proposed  by Lessor or its counsel
                               in the  course of  closing  the  lease  described
                               herein.  Not every provision that imposes duties,
                               obligations, burdens, or limitations on Lessee is
                               contained  herein,  but shall be contained in the
                               final Lease documentation  satisfactory to Lessor
                               and its counsel.

                               EACH  OF  THE  PARTIES  HERETO   IRREVOCABLY  AND
                               UNCONDITIONALLY WAIVES ALL RIGHT TO TRIAL BY JURY
                               IN ANY SUIT,  ACTION,  PROCEEDING OR COUNTERCLAIM
                               ARISING  OUT OF OR RELATED TO

- -------------------------
*Confidental Treatment Requested

<PAGE>

                               THIS LETTER OR THE TRANSACTION  DESCRIBED IN THIS
                               LETTER.

Commitment Fee:                A  Commitment  Fee  equal to  [...***...]  of the
                               total  Equipment  Cost  and  Tenant  Improvements
                               [...***...]   shall  be  due  the   Lessor   upon
                               acceptance of this  Commitment.  The  [...***...]
                               application  Fee  previously  paid by  Lessee  to
                               Lessor  shall be applied to the  Commitment  Fee.
                               The  Commitment  Fee shall then be applied to the
                               cost and expenses incurred by Lessor  [...***...]
                               in  connection  with  the  transaction,  and  the
                               remainder  shall be applied to the second month's
                               rent due  under the  Lease or  subsequent  months
                               until fully utilized. Upon request by Lessee, the
                               Commitment Fee shall be refunded to Lessee if the
                               Lease  Agreement  is not  executed  by March  31,
                               1997.

Commitment Expiration:         This  Commitment  shall expire on March 25, 1997,
                               unless prior thereto  either  extended in writing
                               by the Lessor or accepted  as  provided  below by
                               the Lessee.


- -------------------------
*Confidental Treatment Requested

<PAGE>


Should  you have any  questions,  please  call me.  If you wish to  accept  this
Commitment,  please so indicate by signing and returning the enclosed  duplicate
copy of this letter to me by March 25, 1997.

                                           Yours truly,

                                           TRANSAMERICA BUSINESS CREDIT 
                                           CORPORATION - TECHNOLOGY
                                           FINANCE DIVISION


                                           By:  /s/ Gerald A. Michaud
                                                ------------------------
                                                 Gerald A. Michaud
                                                 Senior Vice President -
                                                 Marketing

Accepted this 25th day of March, 1997

SUGEN, INC.


By:    Christine Gray-Smith
       -----------------------
       Typed or Printed Name


Title: Vice President, Finance
       -----------------------


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     THE SCHEDULE  CONTAINS  SUMMARY  FINANCIAL  INFORMATION  EXTRACTED FROM THE
     COMPANY'S FORM 10-Q FOR THE MONTHS ENDED MARCH 31, 1997 AND IS QUALIFIED IN
     ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER>                                  1,000
       
<S>                             <C>
<PERIOD-TYPE>                  3-MOS
<FISCAL-YEAR-END>                             Dec-31-1997
<PERIOD-START>                                Jan-01-1997
<PERIOD-END>                                  Mar-31-1997
<CASH>                                        13,395
<SECURITIES>                                  36,345
<RECEIVABLES>                                    242
<ALLOWANCES>                                       0
<INVENTORY>                                        0
<CURRENT-ASSETS>                              50,791
<PP&E>                                         9,275
<DEPRECIATION>                                 4,953
<TOTAL-ASSETS>                                55,915
<CURRENT-LIABILITIES>                         11,154
<BONDS>                                        3,311
<COMMON>                                     108,471
                              0
                                        0
<OTHER-SE>                                   (67,021)
<TOTAL-LIABILITY-AND-EQUITY>                  55,915
<SALES>                                            0
<TOTAL-REVENUES>                               1,487
<CGS>                                              0
<TOTAL-COSTS>                                      0
<OTHER-EXPENSES>                               8,006
<LOSS-PROVISION>                                   0
<INTEREST-EXPENSE>                               170
<INCOME-PRETAX>                               (7,474)
<INCOME-TAX>                                       0
<INCOME-CONTINUING>                           (7,474)
<DISCONTINUED>                                     0
<EXTRAORDINARY>                                    0
<CHANGES>                                          0
<NET-INCOME>                                  (7,474)
<EPS-PRIMARY>                                   (.57)
<EPS-DILUTED>                                   (.57)
        


</TABLE>


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