SUGEN INC
10-Q, 1997-11-14
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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================================================================================

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                          -----------------------------

                                    FORM 10-Q
(Mark one)

   X     Quarterly  report  pursuant  to Section  13 or 15(d) of the  Securities
- -------  Exchange Act of 1934.  For the  quarterly  period ended  September  30,
         1997.
         or

- -------  Transition  report  pursuant to Section 13 or 15(d) of the Securities
         Exchange Act of 1934. For the transition period from 
         ___________ to ___________.


                             Commission File Number:
                                     0-24814
                          -----------------------------


                                   SUGEN, Inc.
             (Exact name of registrant as specified in its charter)

              Delaware                                   13-3629196
   (State or other jurisdiction of                    (I.R.S. Employer
   incorporation or organization)                     Identification No.)


               351 Galveston Drive, Redwood City, California 94063
                    (address of principal executive offices)

                                 (650) 306-7700
              (Registrant's telephone number, including area code)


                          -----------------------------



Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required to file such reports),  and (2) has been subject to filing requirements
for the past 90 days. Yes   X    No
                          -----     -----


Indicate the number of shares  outstanding  of each of the  issuer's  classes of
common stock, as of the latest  practicable  date.  Common Stock $.01 par value;
13,258,523 shares outstanding at October 31, 1997.


================================================================================


<PAGE>

<TABLE>

                                                      SUGEN, Inc.

                                                         INDEX
<CAPTION>

                                                                                                PAGE NO.
                                                                                                --------
<S>                                                                                             <C>
PART I.  FINANCIAL INFORMATION

Item 1.           Financial Statements and Notes

                  Condensed Balance Sheets - September 30, 1997
                  and December 31, 1996                                                          3

                  Statements of Operations - for the three and nine
                  months ended September 30, 1997 and 1996                                       4

                  Condensed Statements of Cash Flows - for the nine
                  months ended September 30, 1997 and 1996                                       5

                  Notes to Financial Statements                                                  6

Item 2.           Management's Discussion and Analysis of Financial
                  Condition and Results of Operations                                            8


PART II. OTHER INFORMATION

Item 2.           Sales of Unregistered Securities                                              13

Item 5.           Other Information                                                             13

Item 6.           Exhibits and Reports on Form 8-K                                              14


Signatures                                                                                      15


Exhibit Index                                                                                   16

</TABLE>

                                       2

<PAGE>
<TABLE>

                                                          PART I. FINANCIAL INFORMATION

Item 1.   FINANCIAL STATEMENTS AND NOTES

                                                                   SUGEN, Inc.

                                                            CONDENSED BALANCE SHEETS
                                                                 (In thousands)
<CAPTION>


                                                                                               September 30,            December 31,
                                                                                                   1997                     1996
                                                                                                 ---------               ---------
<S>                                                                                               <C>                     <C>      
ASSETS                                                                                            (unaudited)
Current assets:
        Cash and cash equivalents                                                                 $  25,533               $  24,852
        Short-term investments                                                                       26,521                  31,482
        Accounts receivable                                                                              96                     264
        Prepaid expenses and other current assets                                                       564                     468
                                                                                                  ---------               ---------
              Total current assets                                                                   52,714                  57,066

Property and equipment, net                                                                           3,885                   4,095
Other assets                                                                                          3,548                     775
                                                                                                  ---------               ---------
                                                                                                  $  60,147               $  61,936
                                                                                                  =========               =========

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
        Accounts payable                                                                          $   1,889               $     852
        Accrued liabilities                                                                           7,986                   7,406
        Deferred contract revenue                                                                       625                     375
        Capital lease obligations - current portion                                                   2,067                   1,835
                                                                                                  ---------               ---------
              Total current liabilities                                                              12,567                  10,468

Long-term liabilities:
        Capital lease obligations - non-current portion                                               3,061                   2,938
        Senior custom convertible notes                                                              17,500                    --
                                                                                                  ---------               ---------
              Total long-term liabilities                                                            20,561                   2,938

Stockholders' equity:
        Common stock                                                                                111,049                 108,120
        Deferred compensation                                                                          (826)                   (710)
        Note receivable from stockholder                                                               (883)                   (883)
        Accumulated deficit                                                                         (82,321)                (57,997)
                                                                                                  ---------               ---------
              Total stockholders' equity                                                             27,019                  48,530
                                                                                                  ---------               ---------
                                                                                                  $  60,147               $  61,936
                                                                                                  =========               =========



<FN>


                                                       See accompanying notes.
</FN>
</TABLE>

                                                                  3


<PAGE>

<TABLE>
                                                                    SUGEN, Inc.

                                                              STATEMENTS OF OPERATIONS
                                                      (In thousands, except per share amounts)
                                                                    (unaudited)

<CAPTION>

                                                                      Three Months Ended                     Nine Months Ended
                                                                         September 30,                         September 30,
                                                                  ------------------------------------------------------------------
                                                                    1997               1996              1997                1996
                                                                  --------           --------           --------           --------
<S>                                                               <C>                <C>                <C>                <C>     
Contract revenue (includes amounts from
   related party)                                                 $  1,336           $  2,430           $  4,307           $ 10,338

Costs and expenses:
   Research and development                                          8,728              7,047             25,304             21,379
   General and administrative                                        1,660              1,104              4,650              4,071
                                                                  --------           --------           --------           --------
      Total costs and expenses                                      10,388              8,151             29,954             25,450
                                                                  --------           --------           --------           --------

Operating loss                                                      (9,052)            (5,721)           (25,647)           (15,112)

Other income and expenses:
   Interest income                                                     576                450              1,879              1,738
   Interest expense                                                   (249)              (167)              (593)              (521)
                                                                  --------           --------           --------           --------
      Other income, net                                                327                283              1,286              1,217
                                                                  ========           ========           ========           ========
Net loss                                                          $ (8,725)          $ (5,438)          $(24,361)          $(13,895)
                                                                  ========           ========           ========           ========


Net loss per share                                                $  (0.66)          $  (0.51)          $  (1.86)          $  (1.32)
                                                                  ========           ========           ========           ========

Shares used in computing net loss
  per share                                                         13,137             10,592             13,079             10,521
                                                                  ========           ========           ========           ========

<FN>

                                                      See accompanying notes.
</FN>
</TABLE>
                                                                 4

<PAGE>
<TABLE>

                                                                   SUGEN, Inc.

                                                        CONDENSED STATEMENTS OF CASH FLOWS
                                                 Increase (decrease) in cash and cash equivalents
                                                                  (In thousands)
                                                                   (unaudited)
<CAPTION>

                                                                                                            Nine Months Ended
                                                                                                              September 30,
                                                                                                     -------------------------------
                                                                                                       1997                  1996
                                                                                                     --------              --------
<S>                                                                                                  <C>                   <C>      
Cash flows from operating activities
Net loss                                                                                             $(24,361)             $(13,895)
Adjustments to reconcile net loss to net cash used in
      operating activities:
      Depreciation and amortization                                                                     2,271                 1,673
      Deferred revenue                                                                                    250                (6,558)
      Changes in operating assets and liabilities:
        Prepaid expenses and other current assets                                                          72                   194
        Other assets                                                                                   (1,339)                 (928)
        Accounts payable                                                                                1,037                   400
        Accrued liabilities                                                                               580                 2,346
                                                                                                     --------              --------
Net cash used in operating activities                                                                 (21,490)              (16,768)
                                                                                                     --------              --------

Cash flows from investing activities
Sales/maturities (purchases) of short-term investments, net                                             4,998                15,755
Purchases of property and equipment, net                                                               (1,800)               (1,074)
                                                                                                     --------              --------
Net cash provided by investing activities                                                               3,198                14,681
                                                                                                     --------              --------

Cash flows from financing activities
Proceeds from issuance of common stock, net                                                             1,118                   657
Repurchase of common stock                                                                                --                 (2,698)
Proceeds from issuance of senior custom convertible notes                                              17,500                  --
Proceeds from issuance of warrant                                                                         --                    200
Proceeds from lease financing of property and equipment                                                 1,895                   995
Payments under capital lease obligations                                                               (1,540)               (1,044)
                                                                                                     --------              --------
Net cash provided by (used in) financing activities                                                    18,973                (1,890)
                                                                                                     --------              --------

Net increase (decrease) in cash and cash equivalents                                                      681                (3,977)
Cash and cash equivalents at beginning of period                                                       24,852                 8,226
                                                                                                     --------              --------
Cash and cash equivalents at end of period                                                           $ 25,533              $  4,249
                                                                                                     ========              ========

<FN>
                                                      See accompanying notes.
</FN>
</TABLE>
                                                                 5

<PAGE>



                                   SUGEN, Inc.

                          NOTES TO FINANCIAL STATEMENTS

                                   (Unaudited)


1.       Summary of Significant Accounting Policies

         Basis of Presentation

         The financial information at September 30, 1997 and for the nine months
         ended  September  30,  1997  and 1996 is  unaudited  but  includes  all
         adjustments  (consisting  only of normal recurring  adjustments)  which
         SUGEN,   Inc.  (the  "Company")   considers   necessary  for  the  fair
         presentation  of the financial  position at such date and the operating
         results and cash flows for those periods.  The  accompanying  condensed
         financial  statements  should be read in conjunction with the financial
         statements  and notes  thereto  for the year ended  December  31,  1996
         included  in the  Company's  Form 10-K.  The  results of the  Company's
         operations for any interim period are not necessarily indicative of the
         results of the Company's operations for a full fiscal year.

         Change in Method of Computing Earnings Per Share

         In February  1997,  the  Financial  Accounting  Standards  Board issued
         Statement of Financial Accounting Standards No. 128, Earnings Per Share
         ("SFAS 128").  Effective December 31, 1997, the Company will adopt SFAS
         128. In accordance with the Statement,  the Company will be required to
         change the method  currently  used to  compute  earnings  per share and
         restate all prior periods. The impact of SFAS 128 on the calculation of
         basic and dilutive  earnings per share is expected to have no impact on
         the net loss per share to be presented at year end.


2.       Accrued Liabilities

         The components of accrued liabilities consist of the following:

                                                    September 30,   December 31,
                                                        1997            1996
                                                      ------------  ------------
                                                              (In thousands)

          Accrued research & development services      $3,827            $3,724
          Accrued compensation                            923               883
          Accrued professional fees                       747               524
          Other                                         2,489             2,275
                                                       ------            ------
                                                       $7,986            $7,406
                                                       ======            ======
                                                                   
                                        6


<PAGE>



3.       Senior Custom Convertible Notes

         In September  1997,  the Company  completed  the sale of $17.5  million
         principal  amount of 5% Senior Custom  Convertible  Notes due 2000 (the
         "Notes").  The Notes were sold at par, mature on September 12, 2000 and
         bear  interest at a rate of 5% per annum  (payable  in Common  Stock or
         cash, at the  Company's  option).  Beginning on December 11, 1997,  the
         Notes may be converted,  together with accrued and unpaid  interest and
         subject  to  certain  limitations,  into  shares of  Common  Stock at a
         conversion price equal to the average of the two lowest trade prices of
         the Common Stock during the 20 trading days  immediately  preceding the
         date of conversion  (the  "Conversion  Price").  Beginning  January 19,
         1998, the Conversion  Price may not exceed 115% of the average  closing
         bid price of the  Common  Stock  for the 20  trading  days  immediately
         preceding such date. In connection with the issuance of the Notes,  the
         Company  issued  warrants to  purchase  up to 332,500  shares of Common
         Stock at an  exercise  price of $16.74  per  share.  Cash and  non-cash
         issuance  costs  (including  the fair  value of the  warrants)  totaled
         approximately $2.6 million and are recorded as deferred costs (included
         in Other Assets in the  accompanying  Balance  Sheet at  September  30,
         1997)  to be  amortized  to  expense  over the  term of the  Notes.  No
         purchaser of the Notes will be allowed to convert Notes and/or warrants
         which  would  result in such  person  owning more than 4.9% of the then
         outstanding Common Stock.

         Upon the occurrence of certain  events,  at the election of the holders
         of the Notes,  the  Company  may be required to redeem in cash all or a
         portion of the Notes at redemption prices which are at a premium to the
         face value of the Notes.  If the Notes are not  converted  into  Common
         Stock upon maturity in September  2000, the Notes will be exchanged for
         13.75%  five-year  debentures.  Pursuant to the terms of the Notes,  in
         addition  to  other  covenants,  the  Company  has  agreed  to  certain
         limitations on the incurrence of additional indebtedness.











                                        7


<PAGE>


                                   SUGEN, Inc.

Item 2.         MANAGEMENT'S DISCUSSION AND ANALYSIS
                OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

         In addition to historical  information  contained herein, the following
discussion contains words such as "intends," "believes," "anticipates," "plans,"
"expects" and similar expressions which are intended to identify forward-looking
statements  within the meaning of Section 27A of the  Securities Act of 1933 and
Section  21E of the  Securities  Exchange  Act of 1934 which are  subject to the
"safe harbor"  created by those  sections.  The Company's  actual  results could
differ  significantly  from  the  results  discussed  in  these  forward-looking
statements.  Factors that could cause or contribute to such differences  include
the factors  discussed  below as well as the factors  discussed in the Company's
October 24, 1997 Form S-3 and Form 10-K for the year ended  December  31,  1996.
Readers  are  cautioned  not to place undue  reliance  on these  forward-looking
statements,  which speak only as of the date hereof.  The Company  undertakes no
obligation  to release  the  results of any  revision  to these  forward-looking
statements which may be made to reflect events or circumstances  occurring after
the date hereof or to reflect the occurrence of unanticipated events.

Overview

         SUGEN was founded in July 1991 to  discover  and develop new classes of
small  molecule  drugs  which  target  specific  cellular  signal   transduction
pathways.  These  signalling  pathways  are involved in a variety of chronic and
acute  pathological  diseases,  including  cancer  and  diabetes  as  well as in
dermatologic,  ophthalmic,  neurologic and immune disorders.  The Company's most
advanced  product  candidate  is SU101,  a PDGF TK  signalling  antagonist.  The
Company is in the process of completing the data analysis on a Phase II clinical
trial  for use of SU101 as a  treatment  for  refractory  malignant  glioma  and
currently  expects to initiate a Phase III clinical trial in this  indication in
late 1997,  subject to FDA review of the planned trial design.  A Phase II study
of SU101 in  combination  with BCNU, the  chemotherapy  drug that is part of the
standard  treatment  regimen  in newly  diagnosed  brain  cancer  patients,  was
initiated  recently,  and the Company  currently  expects to initiate a Phase II
clinical  trial of SU101 in  hormone  refractory  prostate  cancer by the end of
1997.  To  date,  over  140  patients  have  been  treated  with  SU101 in seven
Company-sponsored  clinical  trials  including  patients  with  brain,  ovarian,
prostate and non-small  cell lung cancers.  The Company is also  conducting  its
initial Phase I clinical trial for its second cancer product candidate,  SU5416,
a Flk-1/KDR TK  antagonist  which  inhibits  angiogenesis  (the process by which
blood  vessels are  formed).  In addition,  the Company is  conducting a Phase I
clinical trial for SU5271, an EGF TK antagonist, for the treatment of psoriasis.
Through  September  30,  1997,  all of the  Company's  revenue  has been  earned
pursuant  to  collaborations  with  Zeneca  Limited   ("Zeneca"),   ASTA  Medica
Aktiengesellschaft ("ASTA Medica"), Vision Pharmaceuticals L.P., an affiliate of
Allergan,  Inc. and  Allergan,  Inc.  (collectively  "Allergan")  and Amgen Inc.
("Amgen"). SUGEN intends to pursue its drug discovery programs independently and
in collaboration with established pharmaceutical companies.

         The  financial  results for the nine months  ended  September  30, 1997
reflect planned increases in operating expenses necessary for advancing multiple
product  candidates  through the development  process.  The Company has not been
profitable  since  inception  and  expects to incur  substantial  losses for the
foreseeable  future,  primarily due to the expansion of preclinical and clinical
development  activities  as  more  of its  proprietary  cancer-related  programs
progress  toward and into the  clinic.  The  Company  expects  that  losses will
fluctuate from quarter to quarter and that such fluctuations may be substantial.
As of September 30, 1997, the Company's accumulated deficit was $82.3 million.



                                        8

<PAGE>



         In September  1997,  the Company  completed  the sale of $17.5  million
principal amount of 5% Senior Custom Convertible Notes (the "Notes").  The Notes
were sold at par, mature on September 12, 2000 and bear interest at a rate of 5%
per annum (payable in Common Stock or cash at the Company's  option).  Beginning
on December  11, 1997,  the Notes may be  converted,  together  with accrued and
unpaid interest and subject to certain limitations,  into shares of Common Stock
at a conversion price equal to the average of the two lowest trade prices of the
Common  Stock  during  the 20 trading  days  immediately  preceding  the date of
conversion (the "Conversion Price").  Beginning January 19, 1998, the Conversion
Price may not exceed 115% of the average  closing bid price of the Common  Stock
for the 20 trading days immediately  preceding such date. In connection with the
issuance  of the Notes,  the Company  issued  warrants to purchase up to 332,500
shares of  Common  Stock at an  exercise  price of $16.74  per  share.  Cash and
non-cash  issuance  costs  (including  the fair value of the  warrants)  totaled
approximately $2.6 million and are recorded as deferred expenses to be amortized
to expense over the term of the Notes. No purchaser of the Notes will be allowed
to convert Notes and/or  warrants  which would result in such person owning more
than 4.9% of the then outstanding Common Stock.

         Upon the occurrence of certain  events,  at the election of the holders
of the Notes,  the Company may be required to redeem in cash all or a portion of
the Notes at  redemption  prices which are at a premium to the face value of the
Notes.  If the Notes are not  converted  into  Common  Stock  upon  maturity  in
September  2000,  the Notes will be exchanged for 13.75%  five-year  debentures.
Pursuant to the terms of the Notes, in addition to other convenants, the Company
has agreed to certain limitations on the incurrence of additional indebtedness.

Recent Developments

         In November 1997, the Company sold 2,000,000 shares of its Common Stock
in an underwritten public offering at a price of $16.00 per share,  resulting in
net proceeds of  approximately  $29.7 million.  As part of the offering,  Zeneca
purchased  456,000 shares of Common Stock. In addition,  the Company has granted
the  underwriters  an option to purchase an additional  300,000 shares of Common
Stock to cover over-allotments, if any.

Results of Operations

         The  Company's  revenues for the three and nine months ended  September
30, 1997 were $1.3 million and $4.3 million, respectively. These results compare
to revenues of $2.4  million and $10.3  million for the same  periods last year.
Revenues  for the  three and nine  months  ended  September  30,  1997  included
contract  revenue  from the  Allergan  and Zeneca  collaborations  and  contract
services  revenue  earned  under  the ASTA  Medica  collaboration  for  services
rendered by ASTA Medica pursuant to the collaboration  but on  non-collaboration
programs.  In 1996,  revenues  included  contract  revenues earned from existing
collaborations,  set-up fees associated with the ASTA Medica  collaboration  and
wind-down fees in connection  with the  termination  of the Amgen  collaboration
agreement. The Company recognizes revenue from set-up fees and wind-down fees as
the related  activities  are  performed,  which is generally over a twelve-month
period or less.  Through  December 31, 1996,  the set-up and wind-down fees from
the  ASTA  Medica  and  Amgen  collaborations,   respectively,  had  been  fully
recognized  as revenue.  Going  forward,  the  Company  will not  recognize  any
additional revenue under the Amgen  collaboration and will recognize  additional
revenue  under  the ASTA  Medica  collaboration  only  upon the  achievement  of
specified  milestones and for services  rendered by ASTA Medica  pursuant to the
collaboration  but on  non-collaboration  programs.  As a result,  1997 contract
revenue  will  continue  to be lower  than  1996 in the  absence  of  additional
collaboration  agreements  entered into during the current year.  The Company is
actively pursuing additional collaborations, but no assurance can be given as to
the ability of the Company to enter such collaborations on a timely basis, or at
all.



                                       9

<PAGE>



         Research and development  expenses  increased to $8.7 million and $25.3
million for the three and nine months ended  September  30, 1997,  respectively,
from $7.0 million and $21.4 million for the same periods last year. The increase
during 1997 was primarily due to higher personnel  related costs associated with
the expansion of the Company's research and development  programs.  In addition,
the  progression  of clinical  trials,  including  expanded Phase I and Phase II
clinical  trials of the Company's  lead  anti-cancer  compound,  SU101,  and the
initiation  of  clinical  trials for SU5271  and  SU5416  contributed  to higher
expenses during 1997.  Further,  the continued  advancement of multiple programs
through preclinical  development,  including costs associated with the Company's
June 1997 IND filing with the Food and Drug  Administration  ("FDA") for SU5416,
an angiogenesis inhibitor, and for SU101 in combination with BCNU, led to higher
expenses in the first nine months of 1997. The Company expects that its research
and development expenses will continue to grow in future years due to the hiring
of personnel,  additional  preclinical studies, the progression of SU101, SU5416
and other clinical  trials,  the initiation of new clinical trials on additional
drug   candidates,   requirements   under  the  Company's   anticipated   future
collaborations and the expansion of the Company's facilities.

         General and administrative expenses for the three and nine months ended
September 30, 1997 were $1.7 million and $4.7 million,  respectively,  from $1.1
million and $4.1  million for the same periods  last year.  The increase  during
1997 was primarily due to added headcount and higher  consulting  expenses.  The
Company  expects that its general and  administrative  expenses will continue to
increase  in future  periods  in order to support  the  Company's  research  and
development efforts.

         Interest  income for the three and nine months ended September 30, 1997
were $576,000 and $1.9 million, respectively. The Company earned slightly higher
interest income during 1997, despite the decline in interest rates from the same
period last year,  due to higher  investment  balances  arising  primarily  from
issuances of Common Stock.  Interest expense for the three and nine months ended
September  30, 1997 was  $249,000  and  $593,000,  respectively.  The  Company's
interest  expense was higher for the first nine months of 1997 than for the same
period last year,  as the third quarter  interest  expense  included  additional
interest expense related to the Notes. The Company expects that interest expense
will continue to increase in future  periods due to the continued use of capital
lease financing for equipment and facility  improvements and higher debt expense
in connection with the issuance of the Notes.

Liquidity and Capital Resources

         The Company had cash, cash  equivalents  and short-term  investments of
approximately  $52.1 million at September 30, 1997,  compared with approximately
$56.3 million at December 31, 1996. The decrease in cash and investments  during
the nine months ended September 30, 1997 was primarily due to operating  losses,
partially  offset  by the net  cash  proceeds  of  approximately  $16.3  million
received in connection with the issuance of the Notes.

         Through  September  30,  1997,  the  Company's   principal  sources  of
financing have been its initial and follow-on  public offerings of Common Stock,
placements of the Company's Preferred and Common Stock and convertible notes and
funds  received  under the  Company's  corporate  collaborations.  The Company's
current  principal  sources  of  liquidity  are  its  research  and  development
collaborations with ASTA Medica, Zeneca and Allergan, its cash, cash equivalents
and short-term investments and capital lease financing.

         The Company has entered into license and  research  agreements  whereby
the Company funds research projects performed by others or in-licenses compounds
from third  parties.  Some of the  agreements  may  require  the Company to make
milestone and royalty payments.  Under these programs,  commitments for external
research funding are approximately $2.8 million and $1.9 million in 1997 and


                                       10

<PAGE>



1998,  respectively.  Most of these commitments are cancelable within a three to
nine month  period and limit the amounts  payable by the  Company for  sponsored
research under the programs after notice of cancellation by the Company.

         From time to time,  the  Company  evaluates  potential  investments  in
complementary  businesses,  products or technologies.  Currently, the Company is
considering modest investments in such complementary businesses.

         Net  additions of equipment  and  leasehold  improvements  for the nine
months ended  September  30, 1997 and 1996 were $1.8  million and $1.1  million,
respectively,  which  included  $1.9  million  and  $995,000,  respectively,  of
equipment and leasehold improvements financed through the Company's master lease
agreements.  Capital additions during the first nine months of 1997 included the
initial phases of a limited facility  expansion and the continued  investment in
enhancing  the Company's  laboratory  capabilities.  In March 1997,  the Company
secured an  additional  capital lease line in the amount of $3.5 million for the
purchase of equipment and  facilities  improvements.  At September 30, 1997, the
Company  had $2.3  million  available  under this line.  In November  1997,  the
Company  entered into a commitment  for an additional  capital lease line in the
amount  of  $5.0  million  for  the  purchase  of   equipment   and   facilities
improvements. The Company intends to fund future capital expenditure principally
through lease  financing or other debt  arrangements,  although  there can be no
assurance that such financing will be available.

         The Company expects that its capital additions and equipment  purchases
for 1997 will be higher than that of the prior year primarily due to anticipated
facility  improvements  to its  laboratory  and office space.  In June 1997, the
Company entered into a build-to-suit  facility lease agreement.  Construction of
the new facility is targeted for  completion  during the fourth quarter of 1998,
which coincides with the expiration of the Company's  current  facility  leases.
Although the Company has not expended  significant  amounts to date, the Company
expects to invest in facility  improvements  and incur move related costs during
1998 as it approaches building completion.  Accordingly, it is expected that the
Company's  capital lease obligations and related interest expense as well as its
depreciation expense will increase in future periods.

         The Company estimates that its existing capital, after giving effect to
the net  proceeds of its  November  1997 Common Stock  offering,  together  with
facility and equipment financing,  expected revenues from current collaborations
and net  income  from  investment  activities,  will be  sufficient  to fund its
planned  operations  into  2000.  However,  there can be no  assurance  that the
underlying assumed levels of revenue and expense will prove accurate. Whether or
not these  assumptions  prove to be  accurate,  the  Company  will need to raise
substantial  additional  capital to fund its operations.  The Company intends to
seek such  additional  funding  through  collaborative  arrangements,  public or
private equity or debt financing and capital lease transactions;  however, there
can be no assurance  that  additional  financing will be available on acceptable
terms or at all. If additional  funds are raised by issuing  equity  securities,
further  dilution to  stockholders  may result.  In addition,  in the event that
additional funds are obtained through  arrangements with collaborative  partners
or other  partners,  such  arrangements  may require  the Company to  relinquish
rights to certain of its technologies,  product  candidates or products that the
Company would  otherwise seek to develop or  commercialize  itself.  If adequate
funds are not available,  the Company may be required to delay, reduce the scope
of or eliminate one or more of its research or development programs, which could
have a material adverse effect on the Company.

         The Company is at an early stage of  development  and must be evaluated
in light of the  uncertainties  and  complications  present  in a  biotechnology
company.  The  Company has been in  existence  only since 1991 and to date three
drug candidates (SU101, SU5271 and SU5416) have entered clinical



                                       11

<PAGE>



trials.  To  achieve  profitable   operations,   the  Company,   alone  or  with
collaborative  partners, must successfully develop,  manufacture,  introduce and
market its proposed products. There can be no assurance that the Company will be
able to  discover  any  additional  lead  compounds  or develop  any  commercial
products.  The time  necessary  to achieve  market  success  for any  individual
product is long and uncertain.  Products,  if any,  resulting from the Company's
research and development programs are not expected to be commercially  available
for a number of years, even if they are developed  successfully and proven to be
safe and effective.  Before  obtaining  regulatory  clearance for the commercial
sale of any of its products  under  development,  the Company  must  demonstrate
through  preclinical  studies and clinical trials that the potential  product is
safe and efficacious for use in humans for each target  indication.  The failure
to adequately  demonstrate  the safety and efficacy of a product under  clinical
development could delay or prevent regulatory clearance of the potential product
and could have a material adverse effect on the Company. In addition, several of
the  Company's  currently  proposed  products  are  subject to  development  and
licensing arrangements with the Company's collaborators.  Therefore, the Company
is dependent on the research and development efforts of these collaborators with
respect to some of its proposed  products  and is entitled  only to a portion of
the revenues,  if any, realized from the commercial sale of any of the potential
products covered by the  collaborations in many  jurisdictions.  The Company has
experienced  significant  operating  losses  since its  inception.  The  Company
expects  to incur  significant  operating  losses at least for the next  several
years and expects  cumulative  losses to increase as the Company's  research and
development  efforts,  including  preclinical  studies and clinical trials,  are
expanded.  All of the Company's  revenues to date have been received pursuant to
the Company's  collaborations  or interest income from cash, cash equivalent and
short term investments.  Should the Company or its collaborators fail to perform
in accordance with the terms of any of their agreements,  any consequent loss of
revenue  under  the  agreements  could  have a  material  adverse  effect on the
Company's results of operations. The foregoing risks reflect the Company's early
stage of  development  and the nature of the  Company's  industry and  potential
products.  Also inherent at the Company's  stage of  development  are a range of
additional risks, including manufacturing  uncertainties,  the Company's lack of
sales  and  marketing   capabilities,   competition,   uncertainties   regarding
protection  of  patents  and  proprietary  rights,   government  regulation  and
uncertainties regarding pharmaceutical pricing and reimbursement.









                                       12

<PAGE>



                           PART II. OTHER INFORMATION


Item 2.       SALES OF UNREGISTERED SECURITIES

         On September 12, 1997,  the Company  completed the sale of  $17,500,000
principal amount of 5% Senior Custom  Convertible  Notes due 2000 (the "Notes").
The  following  summary of certain  terms of the Notes does not  purport to be a
complete  description of the terms of the Notes and is qualified in its entirety
by  reference to the Note  Purchase  Agreement  and the form of Note,  which are
incorporated  by reference  herein and copies of which are filed as Exhibits 4.1
and 4.2 to the Company's  Form 8-K filed on September  18, 1997.  The Notes were
sold at par,  mature on September 12, 2000 and bear interest at a rate of 5% per
annum  (payable  in cash or, at the  election of the  Company,  shares of Common
Stock  valued at the fair  market  value of the Common  Stock at the time of the
interest  payment).  Beginning on December 11, 1997, the Notes may be converted,
together  with accrued and unpaid  interest and subject to certain  limitations,
into shares of Common  Stock at a  conversion  price equal to the average of the
two lowest trade  prices of the Common Stock as reported on the Nasdaq  National
Market during the 20 trading days immediately preceding the conversion date (the
"Conversion  Price").  Beginning  on January  19,  1998 (the  "Fixed  Conversion
Date"),  the  Conversion  Price may not exceed 115% of the  average  closing bid
price of the Common  Stock for the 20 trading  days  immediately  preceding  the
Fixed Conversion Date.

         No purchaser of the Notes will be allowed to convert  Notes or exercise
Warrants or  Placement  Fee  Warrants  (as defined  below),  or any  combination
thereof, if such conversion or exercise would result in such person beneficially
owning more than 4.9% of the then  outstanding  Common Stock. If at any time the
number of shares  issuable  upon  conversion  of the Notes exceeds the number of
shares of Common  Stock  available  for  issuance in  connection  with the Notes
without obtaining the approval of the Company's  stockholders in accordance with
Nasdaq requirements, then, at the Investors' option, the Company may be required
to redeem from the Investors in cash (at  redemption  prices ranging from 112.5%
to 120%  depending on the date of redemption) a sufficient  principal  amount of
Notes so that the remaining  Notes are fully  convertible.  The Company may also
redeem the Notes in connection  with an acquisition of the Company at redemption
prices ranging from 125% to 130%.  Upon the occurrence  and  continuation  of an
event of default, the Company will be required to redeem the Notes at redemption
prices ranging from 115% to 122.5%.

         If the Notes are not  converted  into Common  Stock,  upon  maturity in
September  2000,  the Notes will be exchanged for 13.75%  five-year  debentures.
Pursuant to the terms of the Notes, in addition to other covenants,  the Company
has agreed to certain limitations on the incurrence of additional  indebtedness.
In connection  with the issuance of the Notes,  the Company  issued  warrants to
purchase up to 262,500 shares of Common Stock at an exercise price of $16.74 per
share (the "Warrants").

          Diaz & Altschul  Capital,  LLC of New York City was placement agent in
the  transaction.  In  consideration  for its services as placement  agent,  the
Company  paid Diaz & Altschul  Capital,  LLC a fee of $875,000 and issued to its
designee,  Diaz & Altschul  Group,  LLC,  warrants to acquire  70,000  shares of
Common  Stock at an  exercise  price of $16.74  per share  (the  "Placement  Fee
Warrants").

         The  offering  of the Notes was made in  reliance  on Section  4(2) and
Regulation  D  promulgated  under the  Securities  Act of 1933,  as amended (the
"Act"),  based on the fact that the offer and sale of the Notes was made without
general  solicitation or advertising to accredited  investors (as defined in the
Act),  each of which made  representations  that such investor was acquiring the
Notes and  Warrants  for its own account for  investment  purposes and agreed to
transfer restrictions and other conditions set forth in the Act.



Item 5.       OTHER INFORMATION

          Anthony B. Evnin, Ph.D. resigned from the Company's Board of Directors
effective  October 1, 1997. This resignation  reflects the normal  transition of
venture capital representatives off the board of directors of companies in which
a venture fund's  investment  stake has been reduced as a result of distributing
venture fund shares.





                                       13

<PAGE>



Item 5.       OTHER INFORMATION (Continued)

          Christine E.  Gray-Smith has indicated her intention to resign as Vice
President,  Finance and Assistant  Secretary  effective November 30, 1997. It is
anticipated  that Ms.  Gray-Smith  will  continue  as an employee of the Company
until January 1998.

         The Company's Board of Directors has appointed Mr. Stephen  Evans-Freke
as Acting Chief  Financial  Officer pending the appointment of a permanent Chief
Financial  Officer.  Ms.  Susan  Kanaya has been  appointed  to the  position of
Treasurer and Chief Accounting Officer,  and Ms. Marta Moreno has been appointed
Assistant Controller.

<TABLE>

Item 6.       EXHIBITS AND REPORTS ON FORM 8-K

(a)      Exhibits
<CAPTION>

     Exhibit Number                      Description
     --------------                      -----------
<S>                      <C>
         3.1             Restated Certificate of Incorporation (2)
         3.2(ii)         Bylaws of the Registrant (1)
         3.3             Certificate of Designation of Series A Junior Participating Preferred Stock of
                         the Registrant (3)
         4.1             Form of Note Purchase Agreement, dated as of September 8, 1997, by and  between the
                         Company and the investors named therein (4)
         4.2             Form of 5% Senior Custom Convertible Note due 2000 (4)
         4.3             Form of Common Stock Purchase Warrant (4)
         27              Financial Data Schedule
<FN>
- ----------------
       (1)          Incorporated  by reference to  identically  numbered  exhibits filed in response to Item 16
                      "Exhibits" of the Company's  Registration  Statement on Form S-1, as amended (File Number
                      33-77074), which became effective October 4, 1994.
       (2)          Incorporated  by reference to  identically  numbered  exhibits filed in response to Item 14
                      "Exhibits"  of the Company's  Annual Report of Form 10-K for the year ended  December 31,
                      1994.
       (3)          Filed as an exhibit to the Form 8-K Current  Report  dated July 26,  1995 and  incorporated
                      herein by reference.
       (4)          Filed as an  exhibit  to the  Form  8-K  Current  Report  dated  September  12,  1997,  and
                      incorporated herein by reference.
</FN>
</TABLE>

 (b)     Reports on Form 8-K

         SUGEN,  Inc. filed a Current  Report on Form 8-K,  dated  September 12,
         1997,  in  connection  with the  private  placement  of  $17.5  million
         aggregate  principal amount of its 5% Senior Custom  Convertible  Notes
         due 2000.

         Additionally,  the  Company  filed a  Current  Report on Form 8-K dated
         October 27, 1997,  in  connection  with the proposed  follow-on  public
         offering of Common Stock by the Company.



                                       14

<PAGE>



                                   SUGEN, Inc.

                                   SIGNATURES


Date:     November 13, 1997                SUGEN, Inc.




By:    /s/ Stephen Evans-Freke             By:   /s/ Christine E. Gray-Smith
        -------------------------------          ---------------------------
       Stephen Evans-Freke                       Christine E. Gray-Smith
       Chairman and                              Vice President, Finance
       Chief Executive Officer                   (Principal Financial Officer)












                                       15

<PAGE>

<TABLE>

                                                      SUGEN, Inc.

                                                     EXHIBIT INDEX

<CAPTION>

     Exhibit Number                      Description
     --------------                      -----------
<S>                      <C>
         3.1             Restated Certificate of Incorporation (2)
         3.2(ii)         Bylaws of the Registrant (1)
         3.3             Certificate of Designation of Series A Junior Participating Preferred Stock of the
                         Registrant (3)
         4.1             Form of Note Purchase Agreement, dated as of September 8, 1997, by and between
                         the Company and the investors named therein (4)
         4.2             Form of 5% Senior Custom Convertible Note due 2000 (4)
         4.3             Form of Common Stock Purchase Warrant (4)
         27              Financial Data Schedule
<FN>
- ----------
       (1)          Incorporated  by reference to  identically  numbered  exhibits filed in response to Item 16
                      "Exhibits" of the Company's  Registration  Statement on Form S-1, as amended (File Number
                      33-77074), which became effective October 4, 1994.
       (2)          Incorporated  by reference to  identically  numbered  exhibits filed in response to Item 14
                      "Exhibits"  of the Company's  Annual Report of Form 10-K for the year ended  December 31,
                      1994.
       (3)          Filed as an exhibit to the Form 8-K Current  Report  dated July 26,  1995 and  incorporated
                      herein by reference.
       (4)          Filed as an  exhibit  to the  Form  8-K  Current  Report  dated  September  12,  1997,  and
                      incorporated herein by reference.

</FN>
</TABLE>

                                                           16


<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     The Company's Form 10-Q for the nine months ended September 30, 1997.
</LEGEND>
       
<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                              DEC-31-1997
<PERIOD-START>                                 JAN-01-1997
<PERIOD-END>                                   SEP-30-1997
<CASH>                                          25,533
<SECURITIES>                                    26,521
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                52,714
<PP&E>                                          10,184
<DEPRECIATION>                                   6,299
<TOTAL-ASSETS>                                  60,147
<CURRENT-LIABILITIES>                           12,567
<BONDS>                                         20,561
<COMMON>                                       111,049
                                0
                                          0
<OTHER-SE>                                     (84,030)
<TOTAL-LIABILITY-AND-EQUITY>                    60,147
<SALES>                                              0
<TOTAL-REVENUES>                                 4,307
<CGS>                                                0
<TOTAL-COSTS>                                        0
<OTHER-EXPENSES>                                25,304
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                 593
<INCOME-PRETAX>                                (24,361)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                            (24,361)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   (24,361)
<EPS-PRIMARY>                                    (1.86)
<EPS-DILUTED>                                    (1.86)
        


</TABLE>


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