OXIGENE INC
SC 13D/A, 1996-07-24
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                  SCHEDULE 13D

                                 (Rule 13d-101)

Information  to be included in  statements  filed  pursuant to Rule 13d-1(a) and
amendments thereto filed pursuant to Rule 13d-2(a).

                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                                (Amendment No. 2)

                                  Oxigene, Inc
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
- --------------------------------------------------------------------------------
                       (Title of Class of Securities)

                                    691828107
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

       Oxigene, Inc, 110 E.59th Street, New York, NY 10022, United States
                              Phone # 212 421 0001
- --------------------------------------------------------------------------------
(Name, Address, Telephone No of Person Authorised to Receive Notices & 
                                Communications)

                                  17 July 1996
- --------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b) (3) or (4), check the following box [ ].

Check the following box if a fee is being paid with this statement [ ]. (A fee
is not required only if the reporting person: (1) has a previous statement on
file reporting beneficial ownership of more than five percent of the class of
securities described in Item 1; and (2) has filed no amendment subsequent
thereto reporting beneficial ownership of less than five percent of such class.
See Rule 13d-7).



<PAGE>


CUSIP No.                                                          691828107
- --------------------------------------------------------------------------------

1)    Names of Reporting Persons/S. S. or I.R.S. Identification Nos. of Above 
      Persons 

      Morgan Grenfell Asset Management Limite, [parent holding company] on
      behalf of subsidiary companies: Morgan Grenfell International Funds
      Management Limited.

- --------------------------------------------------------------------------------
2)    Check the Appropriate Row if a Member of a Group
      (a) See 1) above
      (b) n/a
- --------------------------------------------------------------------------------
3)    SEC Use Only _________________________________________________________
- --------------------------------------------------------------------------------
4)    Source of Funds              OO - Discretionary Funds under Management
- --------------------------------------------------------------------------------
5)    Check if Disclosure of Legal Proceedings is Required Pursuant to 
      Item 2(d) or 2(e) n/a
- --------------------------------------------------------------------------------
6)    Place of Organisation                                          England
- --------------------------------------------------------------------------------
      Number of                     (7) Sole Voting Power            676,600
      Shares Bene-                                                 
      ficially Owned by             (8) Shared Voting Power              n/a
      Each                                                        
      Reporting                     (9) Sole Dispositive Power       698,000
      Person With                                                   
                                    (10) Shared Dispositive Power        n/a
- --------------------------------------------------------------------------------
11)   Aggregate Amount Beneficially Owned by Each Reporting Person

      Morgan Grenfell International Funds Management Limited
      [ineligible institution]                                       698,000
                                                                   
      Aggregated holding                                             698,000
- --------------------------------------------------------------------------------
12)   Check if the Aggregate Amount in Row (11) Excludes Certain Shares  n/a
- --------------------------------------------------------------------------------
13)   Percent of Class Represented by Amount in Row (11)       
      Morgan Grenfell International Funds Management Limited           10.01
      Aggregated                                                       10.01
- --------------------------------------------------------------------------------
14)   Type of Reporting Person                                   HC [of IAs]
- --------------------------------------------------------------------------------


<PAGE>

                                    SIGNATURE

After  reasonable  inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.


                                                                    17 July 1996
                                      -----------------------------------------
                                                                          (Date)

                                                                 /s/ L B Hacking
                                      -----------------------------------------
                                                                     (Signature)

                                                 L B Hacking, Compliance Officer
                                      -----------------------------------------
                                                                (Name and Title)

The original statement shall be signed by each person on whose behalf the
statement is filed or his authorised representative. If the statement is signed
on behalf of a person by his authorised representative (other than an executive
officer or general partner of this filing person), evidence of the
representative's authority to sign on behalf of such person shall be filed with
the statement; provided, however, that a power of attorney for this purpose
which is already on file with the Commission may be incorporated by reference.
The name and any title of each person who signs the statement shall be typed or
printed beneath his signature.


            Attention: Intentional misstatements or omissions of fact
          constitute Federal criminal violations (see 18 U.S.C. 1001).




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